Details of the Drug

General Information of Drug (ID: DM26AMU)

Drug Name
AGK2
Synonyms AGK-2; AGK 2
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 434.3
Logarithm of the Partition Coefficient (xlogp) 5.9
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C23H13Cl2N3O2
IUPAC Name
(E)-2-cyano-3-[5-(2,5-dichlorophenyl)furan-2-yl]-N-quinolin-5-ylprop-2-enamide
Canonical SMILES
C1=CC2=C(C=CC=N2)C(=C1)NC(=O)/C(=C/C3=CC=C(O3)C4=C(C=CC(=C4)Cl)Cl)/C#N
InChI
InChI=1S/C23H13Cl2N3O2/c24-15-6-8-19(25)18(12-15)22-9-7-16(30-22)11-14(13-26)23(29)28-21-5-1-4-20-17(21)3-2-10-27-20/h1-12H,(H,28,29)/b14-11+
InChIKey
SVENPFFEMUOOGK-SDNWHVSQSA-N
Cross-matching ID
PubChem CID
2130404
ChEBI ID
CHEBI:94578
CAS Number
304896-28-4
TTD ID
D0E3NT

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
NAD-dependent deacetylase sirtuin-2 (SIRT2) TTLKF5M SIR2_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 4.4447 7.1582 1.0615 1.6029
SK-PN-DW GDSC2 2.1935 4.0316 1.1406 4.9037
CHSA8926 GDSC2 2.5221 5.4219 0.7023 6.813
EW-24 GDSC2 2.5936 5.1285 0.8986 5.4242
U-CH2 GDSC2 2.5958 14.4596 -3.7405 27.4828
EW-18 GDSC2 2.6288 8.4896 -0.7369 15.0848
TC-71 GDSC2 2.6439 6.7126 0.1564 9.8689
HuO9 GDSC2 2.7735 11.6408 -2.1919 21.6402
EW-7 GDSC2 2.8183 6.9225 0.183 9.2744
ES8 GDSC2 2.8382 8.6962 -0.6778 14.207
EW-12 GDSC2 2.9272 10.3306 -1.4201 17.7956
EW-22 GDSC2 3.0383 5.4312 1.0532 3.5621
CAL-72 GDSC2 3.041 5.3824 1.0776 3.4165
EW-11 GDSC2 3.1228 7.5326 0.1044 9.0243
EW-1 GDSC2 3.2292 10.4861 -1.2673 16.2766
ES5 GDSC2 3.3551 10.5692 -1.2144 15.7033
NOS-1 [Human HNSCC] GDSC2 3.3891 12.7256 -2.2537 20.3042
EW-3 GDSC2 3.5288 12.5384 -2.0557 19.1403
CHSA0011 GDSC2 3.561 7.9401 0.2084 7.4652
ES7 GDSC2 3.6624 6.1672 1.0844 2.3923
CHSA0108 GDSC2 3.8814 16.357 -3.6772 24.1656
CADO-ES1 GDSC2 3.9265 5.9739 1.2969 1.114
ES1 GDSC2 3.9838 6.3098 1.1879 1.5172
ES6 GDSC2 4.0559 8.9047 0.0736 7.2597
U2OS GDSC2; CTRP1 4.1359 6.5591 3.4479 10.1334
EW-13 GDSC2 4.3271 6.5801 1.2376 1.0122
H-EMC-SS GDSC2 4.3799 12.2484 -1.302 13.7903
SaOS-2 GDSC2; CTRP2 4.5009 7.5611 3.3086 8.4173
EW-16 GDSC2 4.5311 10.4437 -0.3451 8.6418
A-673 GDSC2; CTRP2 4.6472 6.0236 4.1942 4.4223
Hs 888.T CTRP2 4.7202 5.7893 4.3764 3.5034
NY GDSC2 4.8329 16.8033 -3.1941 20.5238
HuO-3N1 GDSC2 4.8481 18.0787 -3.807 22.4696
SK-ES-1 GDSC2; CTRP2 4.9519 6.8363 4.0702 4.2771
ES4 GDSC2 5.6738 17.7621 -3.0693 18.4127
Hs 822.T CTRP2 6.5824 11.1445 3.1613 5.3878
TC71 CTRP2 6.6079 7.6532 4.7058 0.1163
SK-N-MC CTRP2 6.6505 7.8181 4.6633 0.1683
HOS GDSC2; CTRP2 7.1897 8.4875 4.6272 0.1028
SW1353 CTRP2 7.1985 8.283 4.6992 0.0416
SJSA-1 GDSC2; CTRP2 7.3604 8.9445 4.5303 0.1896
CAL-78 GDSC2; CTRP2 7.3819 9.6526 4.2756 0.6821
G-292 clone A141B1 GDSC2; CTRP2 7.7371 9.9169 4.3244 0.424
MHH-ES-1 GDSC2; CTRP2 8.1649 18.0319 0.9312 13.038
MG-63 GDSC2; CTRP2 10.6915 19.9971 1.5845 6.387
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 215 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 6.9628 8.0464 4.6975 0.0665
JK1 CTRP2 8.0053 10.4951 4.2182 0.5723
JM1 GDSC2; CTRP2 7.5644 9.0703 4.5607 0.1141
KHM-1B CTRP2 0.5267 45.7566 -19.1892 47.6294
LC4-1 GDSC2 1.1171 4.6907 -0.1371 16.2757
GR-ST GDSC2 1.8605 15.6207 -4.9269 32.3753
MV4-11 GDSC2 2.1317 6.6286 -0.2055 13.4386
Jiyoye GDSC2 2.1323 12.5233 -3.1518 26.9328
EB2 GDSC2 2.3346 5.0903 0.7241 7.1527
TUR GDSC2 2.4146 8.281 -0.802 16.0284
ML-2 GDSC2 2.4768 11.2992 -2.2585 22.7227
BONNA-12 GDSC2 2.4972 6.5945 0.1028 10.574
MEG-01 GDSC2 2.5291 9.1558 -1.1471 17.5209
NK-92MI GDSC2 2.53 5.1714 0.8314 5.9913
MHH-CALL-2 GDSC2 2.6463 6.3486 0.338 8.7553
SUP-B8 GDSC2 2.6601 9.6307 -1.2802 17.8282
Farage GDSC2 2.6667 4.3356 1.3301 2.6496
SUP-T1 GDSC2 2.6873 5.7689 0.6531 6.7183
MY-M12 GDSC2 2.7263 5.1166 0.9976 4.5196
RC-K8 GDSC2 2.7336 10.9298 -1.8692 20.3784
BC-3 GDSC2 2.7379 4.5894 1.2565 2.9446
OCI-AML-2 GDSC2 2.8125 8.2176 -0.4604 13.0629
KE-37 GDSC2 2.8339 5.7351 0.7734 5.6468
DG-75 GDSC2 2.8539 5.8293 0.7418 5.7948
U-698-M GDSC2 2.8587 6.3 0.5168 7.1532
P12-Ichikawa GDSC2 2.9852 6.7353 0.3946 7.6046
ME1 GDSC2 2.9991 4.7166 1.3563 1.9276
Karpas-45 GDSC2 3.0171 5.6421 0.9408 4.2604
PL-21 GDSC2 3.0223 7.9628 -0.1783 10.9191
VAL GDSC2 3.0235 12.0376 -2.1934 20.9859
BC-1 GDSC2 3.0408 7.8854 -0.1268 10.5753
Loucy GDSC2 3.0411 5.2823 1.124 3.1499
SCC-3 GDSC2 3.0474 4.7827 1.3542 1.8658
MOLT-13 GDSC2 3.0503 5.7288 0.9214 4.3095
WSU-NHL GDSC2 3.0663 9.9867 -1.1433 16.0706
IM-9 GDSC2 3.0972 10.9046 -1.5742 18.083
KG-1 GDSC2 3.1124 8.0863 -0.1733 10.674
KMOE-2 GDSC2 3.1156 6.7829 0.4623 6.9088
WIL2 NS GDSC2 3.1372 9.4986 -0.8489 14.3677
HAL-01 GDSC2 3.1421 8.9774 -0.5887 12.95
MLMA GDSC2 3.1498 11.1769 -1.669 18.3857
ATN-1 GDSC2 3.1603 6.4062 0.6727 5.5607
BALL-1 GDSC2 3.2105 5.0568 1.3235 1.7922
MN-60 GDSC2 3.2171 5.4508 1.1524 2.6924
JURL-MK1 GDSC2; CTRP2 3.2577 5.6228 2.9108 13.1513
BE-13 GDSC2 3.2618 6.1852 0.8422 4.3687
KOPN-8 GDSC2 3.3004 6.3985 0.767 4.7321
L-1236 GDSC2 3.3626 14.2469 -3.0283 23.2784
CTB-1 GDSC2 3.3709 6.6191 0.7085 4.9382
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 3.4167 6.5543 2.7105 13.4833
TK [Human B-cell lymphoma] GDSC2 3.4753 5.0374 1.4639 0.8439
CCRF-CEM GDSC2 3.478 7.7631 0.2376 7.4666
QIMR-WIL GDSC2 3.4882 11.5109 -1.5794 17.1288
MOLM-13 GDSC2 3.5198 8.3258 -0.0035 8.7729
MOLT-4 GDSC2 3.5727 6.0223 1.0989 2.4422
P32/ISH GDSC2 3.5953 4.8933 1.571 0.3855
ARH-77 GDSC2 3.6076 8.8582 -0.1994 9.6989
EoL-1 GDSC2; CTRP2 3.6097 6.3813 2.9847 11.8954
KMS-11 GDSC2; CTRP2; CTRP1 3.6551 5.5046 3.3856 10.3116
Karpas-231 GDSC2 3.6653 5.0442 1.5433 0.4285
NOMO-1 GDSC2; CTRP2; CTRP1 3.6669 11.0174 0.8527 20.1691
JSC-1 GDSC2 3.6738 6.8292 0.7966 3.9061
Reh GDSC2 3.6895 5.1636 1.5084 0.522
OCI-AML-3 GDSC2; CTRP2; CTRP1 3.7245 10.9133 0.9568 19.6551
VL51 GDSC2 3.7553 9.7668 -0.5357 11.2362
HH [Human lymphoma] GDSC2 3.8002 6.4114 1.0523 2.3694
SU-DHL-16 GDSC2 3.8431 5.0456 1.6113 0.1861
Ramos.2G6.4C10 GDSC2 3.8884 5.5709 1.4374 0.6261
RPMI-8866 GDSC2 3.9551 11.9115 -1.436 15.3595
LP-1 GDSC2; CTRP2; CTRP1 3.9743 6.7971 3.1771 10.2765
ROS-50 GDSC2 4.0005 7.0098 0.9003 2.8663
OCI-Ly7 GDSC2 4.0263 5.3372 1.5766 0.1972
NKM-1 GDSC2 4.0791 17.1293 -3.9096 24.4198
KMS-28BM CTRP2 4.1991 7.3447 3.1314 9.8358
ALL-PO GDSC2 4.2125 7.2649 0.9025 2.5789
CRO-AP2 GDSC2 4.2339 15.7682 -3.1226 21.5689
MHH-PREB-1 GDSC2 4.2494 6.2271 1.3399 0.7132
Hs 445 GDSC2 4.2544 5.7804 1.5052 0.2661
P30/OHK GDSC2 4.2647 5.8846 1.4721 0.3351
OPM-2 GDSC2; CTRP2 4.34 6.2162 3.8025 6.7603
KMS-34 CTRP2 4.4005 8.6579 2.6765 11.2621
H9 GDSC2 4.4099 6.2576 1.3935 0.4674
CTV-1 GDSC2 4.4175 6.124 1.4446 0.3393
MJ CTRP2 4.4377 24.0245 -4.9559 32.4552
HC-1 GDSC2 4.4846 6.1558 1.4584 0.2857
CESS GDSC2 4.517 6.2331 1.4432 0.3063
BV-173 GDSC2 4.5234 6.2779 1.4298 0.3329
YT GDSC2 4.5519 5.9062 1.5679 0.0977
KY821 GDSC2 4.5668 14.1271 -2.0805 16.8744
Karpas-1106P GDSC2 4.5869 6.2805 1.4524 0.2652
CML-T1 GDSC2; CTRP2 4.6201 8.2062 3.0973 9.0404
HD-MY-Z CTRP2 4.6295 5.9553 4.2095 4.4018
697 GDSC2 4.6876 6.1164 1.544 0.1038
AML-193 CTRP2 4.7473 6.5017 4.0554 4.7686
Daudi GDSC2; CTRP2 4.9025 6.3144 4.2875 3.4663
KMS-12-BM GDSC2; CTRP2 4.9234 10.3708 2.2797 11.8159
AMO1 CTRP2; CTRP1 4.9701 10.4553 2.2863 12.5908
SET-2 CTRP2 5.0139 7.5253 3.7784 5.3803
Karpas-620 GDSC2; CTRP2 5.0474 6.648 4.2451 3.354
GA-10 GDSC2; CTRP2 5.072 6.2444 4.4673 2.373
Pfeiffer CTRP2 5.1035 6.4783 4.3761 2.6972
SUP-M2 GDSC2; CTRP2 5.2036 7.3027 4.0451 3.9032
MOLP-2 CTRP2 5.27 6.9578 4.2686 2.8505
KMS-18 CTRP2 5.3916 7.6588 4.0141 3.7051
EM-2 GDSC2; CTRP2 5.4172 7.3931 4.1644 3.0388
Mono-Mac-1 CTRP2 5.4585 10.0339 2.8858 8.2968
ALL-SIL GDSC2; CTRP2 5.4982 7.2576 4.2894 2.3973
PL21 CTRP1 5.576 15.7328 0.1465 30.3256
CA46 GDSC2; CTRP2 5.6387 8.8506 3.611 4.9703
A3/Kawakami GDSC2; CTRP2 5.6531 9.8739 3.1162 6.9995
SUP-T11 CTRP2 5.6668 8.1765 3.9619 3.4802
HuT 78 CTRP2 5.8529 7.9492 4.1979 2.2669
MOLT-3 CTRP2 6.0723 8.6117 4.0273 2.6505
U266B1 GDSC2; CTRP2 6.0889 8.2224 4.2184 1.8985
DEL GDSC2; CTRP2 6.0901 9.7826 3.48 4.8099
L-540 GDSC2; CTRP2 6.1067 10.6069 3.0911 6.3679
KO52 CTRP2 6.1797 8.1399 4.3091 1.4678
SU-DHL-1 GDSC2; CTRP2 6.2066 11.7058 2.6256 8.1055
Namalwa GDSC2; CTRP2 6.2293 9.2956 3.8066 3.311
Peer CTRP2 6.2529 9.6112 3.6726 3.808
BL-41 GDSC2; CTRP2 6.2635 13.0336 2.0147 10.4612
U-937 CTRP2; CTRP1 6.3081 8.1134 4.4041 1.0813
Kasumi-2 CTRP2 6.3093 9.086 3.9553 2.6351
HL-60 GDSC2; CTRP2 6.3205 7.7386 4.5538 0.5576
EJM GDSC2; CTRP2; CTRP1 6.3207 8.2832 4.3372 1.2954
JVM-2 GDSC2; CTRP2 6.34 9.2974 3.8762 3.3464
SKM-1 GDSC2; CTRP2; CTRP1 6.3806 8.3424 4.3438 1.2185
CMK CTRP2 6.3863 7.5879 4.6423 0.3005
NB4 GDSC2; CTRP2 6.4078 9.8917 3.641 3.7278
SIG-M5 GDSC2; CTRP2 6.4358 7.2881 4.7702 0.0706
BL-70 CTRP2; CTRP1 6.459 7.6062 4.6794 0.2301
NU-DHL-1 CTRP2 6.4926 9.2958 3.97 2.3686
OCI-AML-5 GDSC2; CTRP2 6.4929 8.2907 4.4104 0.8572
KMS-20 CTRP2 6.5247 11.1617 3.1141 5.6563
L-428 GDSC2; CTRP2 6.5387 16.5686 0.4753 15.7002
KMS-26 CTRP2 6.5432 7.7047 4.6627 0.2009
MOLT-16 GDSC2; CTRP2 6.5529 15.3669 1.08 13.5375
THP-1 GDSC2; CTRP2; CTRP1 6.5651 17.2396 0.1737 16.7284
WSU-DLCL2 GDSC2; CTRP2; CTRP1 6.581 8.0834 4.549 0.4666
MC116 GDSC2; CTRP2; CTRP1 6.6016 7.7202 4.6938 0.1713
OCI-Ly3 CTRP2 6.6458 8.0697 4.5684 0.3502
JJN-3 GDSC2; CTRP2 6.6481 13.6863 1.9761 9.9927
SU-DHL-10 GDSC2; CTRP2 6.6699 7.6895 4.7158 0.0982
RL GDSC2; CTRP2 6.6809 8.9024 4.2481 1.2177
Raji GDSC2; CTRP2 6.6895 7.9729 4.6223 0.2261
Ku812 GDSC2; CTRP2; CTRP1 6.6922 13.2395 2.237 10.2703
DoHH2 GDSC2; CTRP2 6.7005 8.0805 4.587 0.2893
KE-97 CTRP2; CTRP1 6.7156 8 4.6368 0.257
L-363 GDSC2; CTRP2 6.7227 8.2689 4.5249 0.413
SR GDSC2; CTRP2 6.7505 8.2316 4.5509 0.3439
RCH-ACV GDSC2; CTRP2 6.7725 12.9147 2.4398 7.9817
HEL GDSC2; CTRP2 6.779 8.0842 4.6168 0.2398
HEL 92.1.7 CTRP2 6.7903 8.0197 4.6444 0.161
M-07e CTRP2 6.8259 8.8825 4.3283 0.8665
OCI-M1 GDSC2; CTRP2 6.8443 7.9871 4.6758 0.1071
JeKo-1 GDSC2; CTRP2 6.8548 8.4693 4.5044 0.3999
SU-DHL-5 GDSC2; CTRP1 6.8749 7.9866 4.7013 0.1058
ME1 CTRP2 6.9122 9.5897 4.0748 1.5873
Mino CTRP2 6.9302 7.9842 4.7072 0.0621
A4/Fukuda GDSC2; CTRP2 6.9347 8.6013 4.4879 0.4017
KCL-22 GDSC2; CTRP2 6.9413 21.4371 -1.6297 23.3464
HT GDSC2; CTRP2; CTRP1 6.9454 8.1383 4.6742 0.1102
Toledo CTRP2 6.9483 8.7778 4.426 0.5368
HPB-ALL CTRP2 6.9612 10.5199 3.691 2.8819
MOLM-6 CTRP2 6.9637 11.5705 3.2086 4.6988
NCI-H929 GDSC2; CTRP2 6.9995 8.4192 4.581 0.2039
HDLM-2 GDSC2; CTRP2 7.0525 13.0321 2.5747 7.0502
F-36P CTRP2 7.0559 10.535 3.7389 2.6098
KMS-27 CTRP2 7.0636 8.64 4.5259 0.2782
SU-DHL-6 GDSC2; CTRP2 7.0763 8.5667 4.5575 0.2363
SK-MM-2 GDSC2; CTRP2 7.0995 8.6037 4.5531 0.2212
TF-1 CTRP2 7.1145 8.1955 4.6997 0.0484
MM1.S GDSC2; CTRP2 7.1834 8.9097 4.4744 0.3332
SUP-HD1 GDSC2; CTRP2 7.2028 10.7724 3.7163 2.5427
SU-DHL-8 GDSC2; CTRP2 7.2232 8.4654 4.6466 0.0846
RPMI-6666 GDSC2; CTRP2 7.2233 8.6519 4.5824 0.1492
SU-DHL-4 GDSC2; CTRP2; CTRP1 7.2315 15.0947 1.716 10.8246
KM-H2 GDSC2; CTRP2 7.2584 9.0813 4.4411 0.4275
Karpas-422 GDSC2; CTRP2 7.2707 8.6212 4.6102 0.108
Jurkat GDSC2; CTRP2 7.273 8.8427 4.5336 0.2374
MOLP-8 GDSC2; CTRP2 7.2749 8.6717 4.5943 0.1249
OCI-Ly19 GDSC2; CTRP2 7.2846 9.1175 4.4382 0.3666
DB GDSC2; CTRP2 7.2911 8.8896 4.5237 0.216
MOTN-1 CTRP2 7.2924 8.95 4.5026 0.249
K-562 GDSC2; CTRP2 7.3444 8.6352 4.6313 0.0773
NALM-6 GDSC2; CTRP2 7.3461 8.8192 4.569 0.1637
MHH-CALL-4 GDSC2; CTRP2 7.3633 9.1677 4.4512 0.3381
SUP-B15 GDSC2; CTRP2 7.3729 8.8853 4.5557 0.1531
NCO2 CTRP2 7.4323 11.1216 3.6894 2.4167
LAMA-84 GDSC2; CTRP2 7.4453 9.3786 4.4062 0.4278
Kasumi-1 GDSC2; CTRP2 7.4529 9.0497 4.5275 0.173
RPMI-8402 GDSC2; CTRP2 7.453 13.7182 2.513 6.7482
Ki-JK CTRP2 7.4636 9.5558 4.3476 0.4812
ST486 GDSC2; CTRP2 7.526 9.0373 4.5584 0.1226
Ri-1 CTRP2 7.55 9.7241 4.32 0.5401
MOLM-16 GDSC2; CTRP2; CTRP1 7.5959 9.4988 4.4358 0.3214
DND-41 GDSC2; CTRP2 7.6535 9.5773 4.4155 0.289
RPMI-8226 GDSC2; CTRP2; CTRP1 7.7036 9.3192 4.5392 0.1324
P3HR-1 CTRP2; CTRP1 7.7848 9.3641 4.5526 0.1142
RS4;11 GDSC2; CTRP2 7.8338 9.8787 4.3763 0.3021
Granta-519 GDSC2; CTRP2 7.8679 9.5297 4.5112 0.1191
KMM-1 CTRP2 7.8948 10.1091 4.3165 0.3855
Hs 611.T CTRP2 7.95 9.5645 4.5281 0.093
EHEB CTRP2 7.9948 9.6824 4.5038 0.1087
JVM-3 GDSC2; CTRP2 8.0022 9.644 4.5194 0.1086
MHH-CALL-3 CTRP2 8.104 10.0688 4.4101 0.1914
KYO-1 CTRP2 8.4266 18.4635 0.9011 11.3294
Mono-Mac-6 GDSC2; CTRP2 8.4917 11.22 4.1456 0.5354
NU-DUL-1 GDSC2; CTRP2; CTRP1 8.5168 24.2274 -1.8186 19.3977
REC-1 CTRP2 9.5022 19.9648 0.8913 9.9677
GDM-1 GDSC2; CTRP2; CTRP1 9.7294 18.2387 1.8342 6.5918
Karpas-299 GDSC2; CTRP2 9.8716 20.2806 0.9746 9.2514
PF-382 GDSC2; CTRP2 10.5139 23.961 -0.3368 12.573
P31/FUJ GDSC2; CTRP2 11.198 29.4397 -2.4845 17.3928
OCI-Ly10 CTRP2; CTRP1 11.566 26.4487 -0.8218 12.7671
⏷ Show the Full List of 215 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 7.4392 9.177 4.4773 0.2491
TE15 CTRP2 7.9329 10.0044 4.3692 0.2867
KYSE-270 GDSC2 3.4774 7.8911 0.1761 7.8257
TE-8 GDSC2 3.57 8.4864 -0.0465 8.9119
T.T GDSC2 3.7159 5.6929 1.3119 1.2502
TE-5 GDSC2; CTRP2 4.253 6.8601 3.4149 8.5471
TE-15 GDSC2 4.552 7.951 0.7858 2.7232
TE-6 GDSC2; CTRP2 4.6409 8.5529 2.9435 9.6384
KYSE-410 GDSC2; CTRP2; CTRP1 5.4744 9.2013 3.323 6.5255
COLO 680N GDSC2; CTRP2 6.1816 11.596 2.6613 8.0008
KYSE-450 GDSC2; CTRP2; CTRP1 6.7 8.5295 4.4256 0.7229
KYSE-510 GDSC2; CTRP2 7.0608 8.7454 4.4858 0.3555
OE19 GDSC2; CTRP2 7.0914 8.4024 4.6212 0.1266
KYSE-140 GDSC2; CTRP2; CTRP1 7.1125 9.1761 4.3566 0.7674
TE-4 GDSC2; CTRP2 7.1834 9.4253 4.2763 0.788
TE-9 GDSC2; CTRP2 7.2129 8.5575 4.6114 0.1162
OE33 GDSC2; CTRP2 7.2369 8.7783 4.5429 0.2008
TE-11 GDSC2; CTRP2 7.3767 9.0044 4.5152 0.2074
OE21 GDSC2; CTRP2 7.3875 11.7911 3.3659 3.6095
TE-1 GDSC2; CTRP2 7.5262 9.1051 4.535 0.1491
KYSE-150 GDSC2; CTRP2 7.5522 13.9455 2.47 6.7829
TE-14 CTRP2 7.5676 9.3486 4.4647 0.235
KYSE-180 GDSC2; CTRP2 7.61 9.1826 4.5384 0.1506
KYSE-30 CTRP2 7.8438 13.0816 3.0495 4.2676
TE-10 GDSC2; CTRP2 7.8749 9.9248 4.3755 0.2921
KYSE-70 GDSC2; CTRP2 8.1191 9.6962 4.5419 0.0655
KYSE-520 GDSC2; CTRP2 8.1854 10.3802 4.3307 0.2808
EC-GI-10 GDSC2; CTRP2 8.6973 17.9583 1.3189 9.5199
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 7.8466 9.2517 4.5972 0.0529
PL4 GDSC2 2.8694 11.1327 -1.8636 19.9894
KP-4 GDSC2 2.9879 5.2204 1.1197 3.2707
KP-1N GDSC2 3.4938 5.6095 1.2356 1.8573
MZ-PC-1 GDSC2 3.7175 6.6469 0.9037 3.2561
SNU-410 CTRP2 4.3987 6.8525 3.5586 7.6144
MIA PaCa-2 GDSC2; CTRP2 4.5046 5.6605 4.2202 4.6699
QGP-1 GDSC2; CTRP2; CTRP1 4.9341 7.5017 3.732 5.8173
PaTu 8988s CTRP2 5.0729 6.2826 4.4489 2.4485
PSN1 GDSC2; CTRP2 6.1477 12.3944 2.2435 9.7423
SU.86.86 GDSC2; CTRP2 6.3774 9.3575 3.8717 2.8723
SNU-213 CTRP2 6.4259 8.112 4.4516 0.7819
PaTu 8988t GDSC2; CTRP2 6.6178 8.4922 4.3882 0.8344
YAPC GDSC2; CTRP2 6.6847 7.8808 4.6538 0.174
Panc 03.27 GDSC2; CTRP2; CTRP1 6.7952 8.4625 4.4954 0.488
Capan-1 GDSC2; CTRP2 6.9102 8.4651 4.529 0.3261
PaTu 8902 GDSC2; CTRP2; CTRP1 6.9419 8.1796 4.6586 0.1302
L3.3 CTRP2 7.1338 8.4 4.6373 0.1009
KP-3 GDSC2; CTRP2; CTRP1 7.1895 11.7263 3.2892 4.8216
HPAC GDSC2; CTRP2; CTRP1 7.1906 8.9461 4.4778 0.3568
Panc 05.04 CTRP2 7.2462 8.9127 4.4981 0.2699
DAN-G GDSC2; CTRP2 7.3536 8.6911 4.6156 0.0903
PK-59 CTRP2 7.3877 9.2747 4.4215 0.362
HPAF-II GDSC2; CTRP2 7.4256 14.9867 1.8904 10.4355
HuP-T3 GDSC2; CTRP2 7.4389 9.172 4.479 0.2465
CFPAC-1 GDSC2; CTRP2; CTRP1 7.4482 13.6964 2.5321 6.7497
Panc 02.03 GDSC2; CTRP2 7.4721 9.3309 4.4344 0.3108
Panc 10.05 GDSC2; CTRP2; CTRP1 7.5432 9.3223 4.479 0.245
SW1990 GDSC2; CTRP2 7.5888 13.683 2.6167 6.1786
Panc 04.03 GDSC2; CTRP2 7.6037 10.4826 4.0465 1.1575
Capan-2 GDSC2; CTRP2; CTRP1 7.6361 11.5311 3.6342 2.4772
TCC-Pan2 CTRP2 7.6845 9.3703 4.5004 0.1612
Hs 766T GDSC2; CTRP2 7.7128 9.333 4.5234 0.13
KP-2 GDSC2; CTRP2 7.7992 13.8677 2.6626 5.7472
PK-45H CTRP2 7.8262 9.8668 4.3777 0.302
Panc 08.13 GDSC2; CTRP2 7.9097 9.5213 4.5286 0.0973
HuP-T4 GDSC2; CTRP2; CTRP1 8.3051 12.8876 3.4042 2.6538
SUIT-2 GDSC2; CTRP2; CTRP1 8.3442 16.1743 1.9423 7.804
BxPC-3 GDSC2; CTRP2 8.417 26.0193 -2.7823 21.8081
AsPC-1 GDSC2; CTRP2 8.6069 15.3434 2.4736 5.5125
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 75 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 7.9186 10.2077 4.2898 0.4264
G-mel GDSC2 2.2996 4.0141 1.2304 4.068
A-431 GDSC2 2.4669 5.1525 0.7939 6.3792
CP66-MEL GDSC2 2.7266 5.3891 0.8662 5.3195
COLO 783 GDSC2 2.7632 4.8997 1.1262 3.6669
CP50-MEL-B GDSC2 2.7697 5.4871 0.8488 5.3298
COLO 679 GDSC2 2.8228 6.4596 0.4132 7.8681
MMAc-SF GDSC2 2.8484 5.5253 0.8845 4.9421
GAK GDSC2 2.9635 9.692 -1.0755 15.9903
VMRC-MELG GDSC2 3.0246 20.8698 -6.5953 32.7795
Hs 938.T GDSC2 3.05 6.1678 0.7128 5.5489
WT2-iPS GDSC2 3.2228 7.563 0.1599 8.4704
A-388 GDSC2 3.243 10.8804 -1.4516 17.1349
MZ-MEL-2 GDSC2 3.3046 7.8614 0.0724 8.8022
M14 GDSC2 3.3348 8.8865 -0.4042 11.4643
DJM-1 GDSC2 3.5197 11.6432 -1.6211 17.2448
451Lu GDSC2 3.5419 12.0867 -1.8231 18.1022
LB373-MEL-D GDSC2 3.6412 5.1942 1.4763 0.6635
WM1552C GDSC2 3.6846 5.9104 1.2061 1.7646
WM35 GDSC2 3.7866 9.9016 -0.5792 11.4024
SH-4 GDSC2 3.809 6.1194 1.181 1.7376
COLO 741 CTRP1 4.0752 5.246 3.9289 15.1679
MZ-MEL-7 GDSC2 4.2458 5.6855 1.5353 0.2101
Hs 688(A).T CTRP2 4.3017 5.7822 3.9585 6.235
WM278 GDSC2 4.3872 6.9607 1.1143 1.4389
LB2518-MEL GDSC2 4.415 5.7358 1.578 0.1076
HMV-II GDSC2 4.4895 9.292 0.1605 6.0183
IST-MEL1 GDSC2 4.6804 7.0372 1.2133 0.8499
RPMI-7951 GDSC2; CTRP2 4.7099 5.6084 4.4512 3.2245
WM115 GDSC2; CTRP2 4.9393 5.5319 4.7084 1.6292
UACC-257 GDSC2; CTRP2 5.0486 8.6522 3.244 7.5586
WM266-4 CTRP2 5.1745 6.2927 4.5251 1.9441
HT-144 GDSC2; CTRP2 5.2336 8.4769 3.4832 6.2058
UACC-62 GDSC2; CTRP2 5.4653 7.2122 4.2881 2.4528
WM983B CTRP2 5.5005 7.9331 3.9603 3.7485
CHL-1 GDSC2 5.5937 18.7814 -3.6172 20.3928
SK-MEL-28 GDSC2; CTRP2; CTRP1 5.5973 9.5917 3.224 6.725
RVH-421 GDSC2; CTRP2 5.6126 9.1278 3.4548 5.6615
A-375 GDSC2; CTRP2; CTRP1 5.6979 10.6898 2.7566 8.4884
SK-MEL-1 GDSC2; CTRP2; CTRP1 5.7381 7.6454 4.2784 2.1758
CJM [Human melanoma] CTRP2 6.1204 10.8986 2.9584 6.888
Hs 839.T CTRP2 6.3827 7.5259 4.6643 0.2551
A2058 GDSC2; CTRP2 6.387 7.24 4.7693 0.0802
IPC-298 GDSC2; CTRP2 6.5915 8.0276 4.5614 0.3902
SK-MEL-2 GDSC2; CTRP2 6.6499 7.5047 4.7716 0.0415
A101D GDSC2; CTRP2 6.6877 8.3476 4.479 0.5414
MeWo GDSC2; CTRP2 6.8 11.777 3.0048 5.7084
Hs 940.T GDSC2; CTRP2 6.9057 9.7669 3.9945 1.8623
K029AX CTRP2 6.9073 8.2153 4.6189 0.1698
IGR-37 GDSC2; CTRP2 6.9191 8.1614 4.6423 0.1343
HMCB CTRP2 6.9251 8.1748 4.6398 0.1364
Mel Ho GDSC2; CTRP2 6.9518 8.4162 4.5636 0.2848
SK-MEL-5 GDSC2; CTRP2; CTRP1 6.9959 8.4234 4.5923 0.2139
IGR-39 CTRP2 7.0189 8.4288 4.585 0.1927
SK-MEL-30 GDSC2; CTRP2 7.0341 8.3149 4.6308 0.1259
SK-MEL-3 GDSC2; CTRP2 7.0509 13.6156 2.2938 8.1479
WM1799 CTRP2 7.062 8.1885 4.6841 0.0661
MDA-MB-435S CTRP2 7.1218 8.4033 4.6319 0.1087
Mel JuSo GDSC2; CTRP2 7.1542 8.6001 4.5751 0.1741
WM88 CTRP2 7.1645 8.8409 4.4922 0.3063
WM793 GDSC2; CTRP2 7.1818 8.7776 4.5221 0.2485
Hs 895.T CTRP2 7.2582 8.772 4.5531 0.181
Hs 944.T CTRP2; CTRP1 7.2804 11.2691 3.5515 3.1143
COLO 800 GDSC2; CTRP2 7.3016 13.9752 2.2911 7.8041
SK-MEL-31 GDSC2; CTRP2 7.3447 8.5435 4.6622 0.0532
Hs 936.T CTRP2; CTRP1 7.3933 8.1787 4.8109 0.0035
Hs 294T CTRP2 7.4312 8.6276 4.6636 0.045
G-361 GDSC2; CTRP2; CTRP1 7.4563 8.9156 4.5896 0.118
COLO 792 GDSC2; CTRP2 7.4845 9.2428 4.471 0.2468
LOX-IMVI GDSC2; CTRP2 7.5018 9.0826 4.534 0.155
SK-MEL-24 GDSC2; CTRP2 7.6745 9.4359 4.4738 0.1971
Hs 852.T CTRP2; CTRP1 7.8702 9.1622 4.6488 0.0327
COLO 829 GDSC2; CTRP2 7.9167 9.7959 4.4368 0.1949
IGR-1 GDSC2; CTRP2 10.5215 23.493 -0.1128 11.9006
EquiPSC Line K2 GDSC2 4.2782 15.3146 -2.8673 20.5699
⏷ Show the Full List of 75 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FLO-1 GDSC2 2.9089 9.8014 -1.1716 16.6206
OACM5.1 C GDSC2 3.1943 7.9247 -0.0357 9.6828
KYSE-220 GDSC2 3.5214 6.1523 1.0128 2.9717
TE-12 GDSC2 3.5832 12.641 -2.0656 19.0498
HCE-4 GDSC2 3.7212 8.0087 0.2804 6.7336
KYAE-1 GDSC2 3.8229 5.7142 1.3531 0.9813
OACP4 C GDSC2 4.0696 8.5184 0.2616 6.1915
ESO-26 GDSC2 4.175 6.2061 1.3163 0.8427
KYSE-50 GDSC2 4.1912 5.9522 1.4189 0.5062
SK-GT-4 GDSC2 4.3922 8.7889 0.3311 5.2661
ESO-51 GDSC2 4.4851 6.5422 1.3187 0.6386
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2; CTRP2 5.5142 9.3993 3.245 6.7023
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LA-N-6 GDSC2 2.3954 5.2986 0.6675 7.3493
SK-N-MC-IXC GDSC2 2.5996 4.4006 1.2552 3.2311
NB(TU)1 GDSC2 2.7214 6.2751 0.4298 8.0085
TGW GDSC2 2.823 5.0366 1.1006 3.6986
SJNB-6 GDSC2 2.8641 4.4599 1.3937 1.936
SJNB-13 GDSC2 2.9732 7.6325 -0.0521 10.3003
SJNB-17 GDSC2 2.9735 12.9873 -2.7049 23.1056
MHH-NB-11 GDSC2 3.2502 5.3443 1.219 2.281
KP-N-YS GDSC2 3.2823 6.3854 0.7616 4.7977
IMR-5 GDSC2 3.3939 7.4193 0.3455 7.0112
SiMa GDSC2 3.446 6.7675 0.6866 4.9242
SJNB-10 GDSC2 3.4921 12.2283 -1.9301 18.6919
KP-N-RT-BM-1 GDSC2 3.5879 6.354 0.9606 3.1496
SJNB-14 GDSC2 3.6742 5.3375 1.4349 0.7896
SJNB-5 GDSC2 3.9104 11.5174 -1.2759 14.6951
NH-12 GDSC2 3.9729 6.3081 1.1833 1.5484
SJNB-12 GDSC2 4.05 7.6478 0.6462 4.1219
CHP-134 GDSC2 4.1231 5.6542 1.5006 0.3246
SK-N-BE(2)-M17 GDSC2 4.3007 6.3576 1.3119 0.7718
GI-ME-N GDSC2 4.3386 15.1604 -2.7476 19.9986
GOTO GDSC2 4.4443 6.4457 1.338 0.6042
NB69 GDSC2 4.8279 6.7985 1.3594 0.3765
SJNB-7 GDSC2 5.3009 18.2353 -3.5583 20.7767
SK-N-DZ GDSC2; CTRP2 5.4975 7.1763 4.3283 2.2397
SK-N-BE(2) CTRP2 6.3417 11.3607 2.8912 6.8204
IMR-32 CTRP2 6.5049 7.9003 4.5731 0.4043
KP-N-YN CTRP2 6.691 13.2881 2.2011 9.0451
CHP-126 GDSC2; CTRP2 6.7038 9.2968 4.0899 1.7236
CHP-212 GDSC2; CTRP2 6.7301 12.2629 2.725 6.9135
NB1 CTRP2 6.9768 8.2317 4.6389 0.127
SK-N-FI GDSC2; CTRP2 6.9778 8.4232 4.5712 0.226
NH-6 CTRP2 7.0154 8.6393 4.5069 0.3307
SK-N-AS GDSC2; CTRP2 7.0405 8.5288 4.5573 0.2309
SK-N-SH GDSC2; CTRP2 7.4416 9.3766 4.4055 0.3736
KP-N-SI9s CTRP2 7.557 9.0113 4.5782 0.0979
Kelly GDSC2; CTRP2 9.9298 20.9633 0.6944 10.0958
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2; CTRP2 6.9963 8.7195 4.4689 0.4166
SNU-478 CTRP2 7.0648 9.5235 4.1804 1.1346
SNU-1196 CTRP2 7.1965 12.3115 3.0095 5.1725
HuH-28 CTRP2 7.2955 8.4838 4.6653 0.0557
SNU-1079 CTRP2 7.3126 9.334 4.3684 0.4998
SNU-869 CTRP2 7.3481 9.172 4.4435 0.3345
SNU-308 CTRP2 7.4068 9.5602 4.322 0.5613
SNU-245 CTRP2 8.1913 25.7834 -2.8336 22.2584
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 578Bst CTRP2 2.575 4.9354 2.3784 17.1361
Evsa-T GDSC2 2.7729 7.6368 -0.203 11.6831
HCC1599 GDSC2 2.8158 7.4535 -0.0803 10.8536
MRK-nu-1 GDSC2 2.8287 5.8318 0.723 5.9648
BT-483 GDSC2 2.9371 5.7587 0.8326 5.0671
MDA-MB-436 GDSC2 3.0107 7.6516 -0.0342 10.1049
OCUB-M GDSC2 3.2167 5.0184 1.3436 1.6816
YMB-1-E GDSC2 3.4943 5.7214 1.1876 2.0966
UACC-893 GDSC2 3.5292 10.9292 -1.2631 15.5213
HCC70 GDSC2 3.5898 8.1921 0.1076 7.9871
MDA-MB-175-VII GDSC2 3.6827 7.3891 0.5453 5.2972
EFM-19 GDSC2 3.987 7.4187 0.7127 3.864
COLO 824 GDSC2 4.1401 6.7783 1.0707 1.8733
HCC1187 GDSC2 4.1539 10.316 -0.529 10.3551
UACC-812 GDSC2 4.2205 12.282 -1.4287 14.7337
MFM-223 GDSC2 4.347 11.7171 -1.0691 12.728
MDA-MB-157 GDSC2; CTRP2 4.3935 15.1463 -0.5587 23.1499
CAL-120 GDSC2; CTRP2 4.8737 5.8047 4.514 2.5821
DU4475 GDSC2; CTRP2 5.115 8.1713 3.5394 6.191
KPL-1 CTRP2 5.1296 6.8546 4.2093 3.3492
MDA-MB-453 GDSC2; CTRP2 5.4783 9.2491 3.2918 6.5692
MDA-MB-330 GDSC2 6.283 23.8834 -5.6102 24.5251
HCC1569 GDSC2; CTRP2 6.3273 10.0968 3.4908 4.4289
MDA-MB-361 GDSC2; CTRP2 6.4587 12.3072 2.5135 9.3696
Hs 578T GDSC2; CTRP2 6.6222 12.3495 2.6085 7.5349
CAMA-1 GDSC2; CTRP2 6.6962 8.33 4.4897 0.51
HMC-1-8 CTRP2 6.8099 7.8556 4.7087 0.0887
BT-474 GDSC2; CTRP2 6.8336 8.1291 4.6217 0.1844
CAL-85-1 GDSC2; CTRP2 6.8604 15.8311 1.0795 13.0337
MDA-MB-468 GDSC2; CTRP2 6.9051 11.3529 3.2732 4.5233
HCC2218 GDSC2; CTRP2 7.136 8.9924 4.4239 0.4546
HCC1500 GDSC2; CTRP2 7.1751 8.8246 4.5024 0.2845
CAL-148 GDSC2; CTRP2 7.1756 8.5641 4.5956 0.142
MCF-7 GDSC2; CTRP2; CTRP1 7.2161 14.9953 1.7534 10.0485
ZR-75-30 GDSC2; CTRP2 7.2617 11.6829 3.3405 3.8426
HCC202 CTRP2 7.2818 10.2298 3.9934 1.5451
HDQ-P1 GDSC2; CTRP2 7.2978 9.0667 4.4622 0.3169
MDA-MB-231 GDSC2; CTRP2 7.2992 9.1208 4.4429 0.3525
SK-BR-3 CTRP2 7.3126 9.0919 4.4589 0.3182
HCC1419 GDSC2; CTRP2 7.3865 15.5744 1.5804 10.3782
EFM-192A GDSC2; CTRP2 7.4335 9.322 4.4223 0.3448
ZR-75-1 CTRP2 7.4962 8.7228 4.654 0.0457
HCC1428 GDSC2; CTRP2 7.5021 14.3369 2.2521 7.6792
HCC1954 GDSC2; CTRP2 7.5058 9.3442 4.4427 0.3307
CAL-51 GDSC2; CTRP2 7.5789 9.009 4.5867 0.0874
HCC38 GDSC2; CTRP2 7.5828 9.3964 4.4534 0.2482
HCC1395 GDSC2; CTRP2 7.6396 13.2155 2.8658 5.1776
AU565 GDSC2; CTRP2 7.6992 9.8558 4.3318 0.4233
HCC1143 GDSC2; CTRP2 7.7037 9.9446 4.3006 0.4832
HCC1806 GDSC2; CTRP2 7.8816 9.2549 4.6078 0.0511
BT-20 GDSC2; CTRP2 8.3422 14.889 2.5233 5.6275
MDA-MB-415 GDSC2; CTRP2 9.7102 18.7787 1.5659 7.4609
T-47D GDSC2; CTRP2 10.3505 19.4492 1.6357 6.5565
BT-549 GDSC2; CTRP2 11.3945 25.9555 -0.7118 12.61
JIMT-1 GDSC2; CTRP2 11.6376 22.9679 0.7979 7.9219
HCC1937 GDSC2; CTRP2 12.6591 31.297 -2.4082 15.5226
BT147 CTRP2 3.6704 5.5552 3.3799 10.2032
BT 428 CTRP2 3.7569 5.0178 3.6465 8.9628
BT 498 CTRP2 3.8953 5.1891 3.7481 8.1765
BT 444 CTRP2 3.9025 4.8187 3.8518 7.7814
BT 271 CTRP2 4.9693 7.2804 3.8632 5.1116
BT 286 CTRP2 4.9956 7.3203 3.8655 5.0504
BT 216 CTRP2 5.0685 11.9568 1.6083 14.2249
BT 131 CTRP2 5.108 6.5982 4.3198 2.9252
BT 422 CTRP2 5.1572 8.8502 3.2346 7.3907
BT 416 CTRP2 5.4466 8.813 3.4839 5.8225
BT 172 CTRP2 5.4819 7.6625 4.0797 3.2847
BT 482 CTRP2 5.4991 7.6011 4.1223 3.0814
BT 359 CTRP2 6.1907 21.726 -2.3614 24.4211
BT164 CTRP2 6.4988 8.0664 4.5049 0.5817
BT 112 CTRP2 6.5381 7.9562 4.5659 0.4052
BT 139 CTRP2 6.5736 15.8301 0.8669 14.272
BT 245 CTRP2 6.594 9.3097 4.0228 2.0675
BT 504 CTRP2 6.609 8.9461 4.1915 1.4653
BT 159 CTRP2 6.6531 9.3964 4.0178 2.0251
BT 179 CTRP2 6.6981 7.9235 4.6436 0.1868
BT 232 CTRP2 6.7378 10.5384 3.5477 3.6747
BT 330 CTRP2 6.7548 13.1717 2.3028 8.5481
BT 440 CTRP2 6.7707 8.2881 4.5379 0.3631
BT 328 CTRP2 6.8484 14.7512 1.6 11.123
BT 320 CTRP2 6.8512 7.9875 4.6781 0.1031
BT 224 CTRP2 7.0505 8.1709 4.686 0.0658
BT 239 CTRP2 7.1484 14.7145 1.8307 9.7884
BT 231 CTRP2 7.186 10.0286 4.0296 1.5068
BT 145 CTRP2 7.2679 8.7922 4.5496 0.1838
BT 187 CTRP2 7.7652 13.2313 2.9348 4.775
BT 248 CTRP2 8.3082 22.3349 -1.0548 17.6197
BT 333 CTRP2 8.9957 17.8127 1.5758 8.2494
BT 340 CTRP2 11.8137 28.3847 -1.5819 14.4531
BT 228 CTRP2 11.991 25.7229 -0.2395 10.6219
⏷ Show the Full List of 90 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 6.733 8.0322 4.6178 0.2203
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
M059J GDSC2 2.686 5.5585 0.755 6.0943
GI-1 GDSC2 3.0421 7.8403 -0.1038 10.4376
D-542MG GDSC2 3.1396 6.5423 0.594 6.0709
AM-38 GDSC2 3.1669 5.4531 1.1217 2.9446
D-423MG GDSC2 3.2022 8.5007 -0.311 11.2506
D-336MG GDSC2 3.239 6.4597 0.6989 5.2483
H4 GDSC2 3.3021 10.664 -1.3005 16.2585
D-566MG GDSC2 3.32 5.5504 1.1668 2.454
KINGS-1 GDSC2 3.3479 10.1268 -1.0021 14.6484
Onda 11 GDSC2 3.3894 9.3043 -0.5689 12.2481
D-247MG GDSC2 3.4107 5.7622 1.1238 2.5467
KNS-81-FD GDSC2 3.4173 11.1476 -1.4531 16.7093
SK-MG-1 GDSC2 3.4594 8.2875 -0.0263 9.0345
D-263MG GDSC2 3.7615 5.2029 1.5233 0.4344
KS-1 [Human Krukenberg tumour] GDSC2 3.7753 8.6524 0.0115 8.1552
D-502MG GDSC2 3.834 6.0714 1.2134 1.5616
LN-405 GDSC2 3.9271 12.2174 -1.6053 16.2112
D-245MG GDSC2 3.9809 8.9203 0.0186 7.7089
CAS-1 GDSC2; CTRP2 4.0842 13.3448 0.0692 21.859
Onda 10 GDSC2 4.1933 14.1654 -2.3658 18.8575
LNZTA3WT4 GDSC2 4.1962 6.7182 1.1227 1.5852
SF268 GDSC2; CTRP2 4.3826 8.0334 2.968 10.0932
MOG-G-UVW GDSC2 4.6015 6.6351 1.3311 0.5425
GB-1 GDSC2; CTRP2 4.6852 5.9042 4.2878 4.5565
KALS-1 GDSC2; CTRP2 4.7386 7.6415 3.483 7.1781
LN-229 GDSC2; CTRP2; CTRP1 4.857 6.0186 4.4019 3.1747
MOG-G-CCM GDSC2 4.9076 7.1175 1.2753 0.5454
Hs 683 GDSC2; CTRP2 5.0972 6.7853 4.2175 3.3752
SW1088 GDSC2; CTRP2 5.1711 7.5737 3.8837 4.6395
U-251MG GDSC2; CTRP2 5.2059 8.1214 3.6383 5.6055
SF539 GDSC2; CTRP2 5.4009 7.6867 4.0073 3.7176
ONS-76 GDSC2; CTRP2 5.508 8.2234 3.8228 4.3065
KNS-60 CTRP2 5.5824 7.469 4.2459 2.4493
Daoy GDSC2; CTRP2 5.6313 10.8585 2.6108 10.4984
D-392MG GDSC2 5.9491 17.601 -2.8055 16.9525
SF126 GDSC2; CTRP2 6.1367 8.052 4.3238 1.6834
CCF-STTG1 CTRP2 6.2192 7.7074 4.5177 0.7333
SNU-489 CTRP2 6.2665 8.8268 4.0486 2.3319
KNS-81 CTRP2 6.3068 7.211 4.7497 0.1246
SNU-626 CTRP2 6.5008 8.2055 4.4494 0.736
SNU-466 CTRP2 6.6172 8.2009 4.5053 0.5132
GMS-10 CTRP2 6.6204 7.8885 4.6258 0.2428
SNU-1105 CTRP2 6.6603 7.6401 4.7294 0.0782
LN-18 GDSC2; CTRP2 6.6963 7.6888 4.7255 0.0767
M059K CTRP2 6.7195 7.9871 4.6289 0.2052
SNU-738 CTRP2 6.8004 8.6841 4.3966 0.6928
U-118MG GDSC2; CTRP2 6.9219 8.3096 4.5907 0.2099
TM-31 CTRP2 6.9445 8.1256 4.664 0.103
NMC-G1 GDSC2; CTRP2 6.9516 8.6062 4.4931 0.3836
DBTRG-05MG GDSC2; CTRP2 6.9632 8.5927 4.503 0.3583
YKG-1 GDSC2; CTRP2 7.0456 8.2858 4.6451 0.107
KNS-42 GDSC2; CTRP2 7.0483 8.4029 4.6052 0.1562
DK-MG GDSC2; CTRP2 7.4034 8.8854 4.5667 0.134
YH-13 GDSC2; CTRP2 7.4311 8.6418 4.6589 0.0479
D283 Med GDSC2; CTRP2 7.4478 8.6777 4.6526 0.0506
8-MG-BA GDSC2; CTRP2 7.4839 9.076 4.5297 0.1638
GaMG GDSC2; CTRP2; CTRP1 7.6027 8.7788 4.6856 0.0306
SNB-75 GDSC2; CTRP2 7.6139 11.6496 3.5575 2.699
U-87MG ATCC GDSC2; CTRP2 7.6163 8.708 4.6986 0.0186
SW1783 GDSC2; CTRP2 7.6508 12.257 3.3089 3.5362
GOS-3 CTRP2 7.8272 9.1631 4.6198 0.0415
Becker GDSC2; CTRP2 7.8413 9.3926 4.5483 0.0887
SF295 GDSC2; CTRP2; CTRP1 9.784 19.2364 1.4137 7.9499
KG-1-C CTRP2 10.2564 28.6246 -2.7354 19.1569
SNU-201 CTRP2 10.6858 29.2875 -2.7588 18.6608
42-MG-BA GDSC2; CTRP2 12.5676 33.1728 -3.3526 17.7315
T98G GDSC2; CTRP2 12.6719 24.8646 0.5371 7.7166
A-172 GDSC2; CTRP2 13.0416 29.212 -1.2039 12.1465
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC2 2.8178 6.7172 0.2834 8.6688
ETK-1 GDSC2 3.91 15.066 -3.0176 21.9382
TGBC1TKB GDSC2 4.3212 13.3226 -1.8629 16.4781
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-151 CTRP2; CTRP1 4.377 6.4147 3.7535 6.9559
MFE-280 GDSC2 4.4184 6.7072 1.2281 0.9782
JHUEM-1 CTRP2 5.285 7.4365 4.0425 3.7693
HEC-265 CTRP2; CTRP1 5.8432 6.9288 4.6683 0.7076
EFE-184 CTRP2 5.9302 8.6253 3.9275 3.2352
JHUEM-2 CTRP2; CTRP1 6.7371 8.8715 4.3028 1.2234
MFE-319 GDSC2; CTRP2; CTRP1 6.7817 9.9839 3.8408 2.5941
HEC-108 CTRP2; CTRP1 6.7962 7.9512 4.685 0.1459
HEC-251 CTRP2; CTRP1 6.9871 8.3666 4.6093 0.2191
HEC-59 CTRP2; CTRP1 7.0256 9.4634 4.1994 1.3403
HEC-1-A CTRP2 7.0552 11.808 3.1555 4.7887
MFE-296 GDSC2; CTRP2 7.2069 11.6485 3.3232 3.9697
RL95-2 GDSC2; CTRP2 7.2783 8.8571 4.5305 0.2091
HEC-6 CTRP2; CTRP1 7.3121 8.4294 4.7034 0.0463
EN GDSC2; CTRP2 7.3845 8.5673 4.6678 0.0461
AN3-CA GDSC2; CTRP2 7.3962 8.7735 4.6026 0.0969
JHUEM-7 CTRP2 7.4164 9.0304 4.5209 0.19
ESS-1 GDSC2; CTRP2 7.4465 8.6482 4.662 0.0448
HEC-1-B CTRP2 7.4498 9.5651 4.3383 0.5067
KLE GDSC2; CTRP2; CTRP1 7.5063 9.5054 4.3979 0.3977
HEC-50B CTRP2 7.6225 9.5385 4.4176 0.3155
JHUEM-3 CTRP2 7.7697 9.7367 4.4028 0.2775
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 6.1561 7.4568 4.6039 0.6633
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-704 GDSC2 2.822 5.6895 0.7872 5.5892
BB65-RCC GDSC2 2.9265 5.2692 1.058 3.7467
KTCTL-13 GDSC2 3.0026 5.6548 0.9254 4.3802
SW13 GDSC2 3.0438 8.1138 -0.2366 11.2049
NCC021 GDSC2 3.0442 6.8957 0.3584 7.6892
UO-31 GDSC2 3.0561 6.0018 0.796 5.0405
KTCTL-1M GDSC2 3.1084 5.8269 0.9126 4.249
LB1047-RCC GDSC2 3.1568 8.8466 -0.5136 12.4989
LB2241-RCC GDSC2 3.2168 7.586 0.1446 8.5741
NCC010 GDSC2 3.2904 12.2232 -2.0801 19.8328
KTCTL-195 GDSC2 3.3672 6.1575 0.92 3.735
KTCTL-26A GDSC2 3.3937 7.6916 0.2152 7.7743
RXF 393L GDSC2 3.76 13.1297 -2.1749 19.083
SN12C GDSC2 3.9375 8.2666 0.2965 6.2357
TUHR14TKB CTRP2 3.9976 5.951 3.5708 18.3809
SW156 GDSC2 4.0313 6.2203 1.2467 1.2232
LB996-RCC GDSC2 4.0797 7.249 0.839 3.0693
KTCTL-21 GDSC2 4.211 16.0931 -3.2995 22.218
KTCTL-140 GDSC2 4.5174 6.5437 1.3312 0.5848
TK-10 GDSC2 4.7879 7.1976 1.1975 0.8337
BFTC-909 GDSC2; CTRP2 4.8384 5.7327 4.5164 2.6515
HA7-RCC GDSC2 5.0201 14.9424 -2.1601 16.2596
VMRC-RCZ GDSC2; CTRP2 5.0841 7.7027 3.7482 5.3722
TUHR10TKB CTRP2 6.392 14.8715 1.2037 13.354
TUHR4TKB CTRP2 6.8281 8.4326 4.5072 0.4055
A-498 GDSC2; CTRP2 6.8454 8.2868 4.569 0.272
RCC10RGB GDSC2; CTRP2; CTRP1 6.8636 11.8551 3.0216 5.6278
Caki-2 CTRP2 7.2433 8.4279 4.6661 0.0603
769-P GDSC2; CTRP2 7.3385 8.6952 4.6089 0.1141
KMRC-1 GDSC2; CTRP2 7.365 8.9003 4.5476 0.1651
KMRC-20 GDSC2; CTRP2 7.3975 17.2025 0.7973 13.189
VMRC-RCW GDSC2; CTRP2; CTRP1 7.5707 9.2768 4.5055 0.1995
OS-RC-2 GDSC2; CTRP2 7.717 9.3273 4.5269 0.1257
CAL-54 GDSC2; CTRP2 7.722 9.5435 4.4536 0.2142
786-O GDSC2; CTRP2 7.7459 9.8725 4.3443 0.3839
ACHN GDSC2; CTRP2 7.7521 9.1697 4.5924 0.0642
Caki-1 GDSC2; CTRP2 8.5001 15.2567 2.4498 5.7156
SNU-1272 CTRP2 8.6334 17.7519 1.3748 9.4059
KMRC-2 CTRP2 9.0735 15.0834 2.8517 3.7435
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 62 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-C5 GDSC2; CTRP2; CTRP1 2.6953 4.7881 2.548 16.2404
SNU-283 GDSC2 2.9923 7.5446 0.0049 9.9179
CaR-1 GDSC2 3.134 6.5976 0.5638 6.263
CW-2 GDSC2; CTRP2; CTRP1 3.1676 6.4945 2.4812 16.2038
SW1463 GDSC2 3.1764 6.6554 0.5646 6.1691
SW620 GDSC2; CTRP2; CTRP1 3.4716 5.2198 3.2802 11.2397
LS180 GDSC2; CTRP2; CTRP1 3.4894 4.9762 3.3679 12.5383
GP2d CTRP2; CTRP1 3.6804 7.6845 2.474 13.8354
HCC2998 GDSC2 3.7084 7.2615 0.6199 4.8301
SW48 GDSC2; CTRP2; CTRP1 3.7576 5.3708 3.5428 9.4277
SW626 GDSC2 3.7707 8.3471 0.153 7.3625
SNU-C4 CTRP2; CTRP1 3.8075 4.9011 3.7328 8.5866
SW480 CTRP1 3.8357 5.3181 3.6452 18.9288
SW837 GDSC2 3.9201 6.6362 1.0189 2.3797
RKO GDSC2; CTRP2; CTRP1 4.0117 5.9899 3.5746 8.5991
KM12 GDSC2; CTRP2; CTRP1 4.0254 5.1832 3.8948 7.3401
COLO 320HSR GDSC2 4.0852 6.4619 1.1743 1.4742
SK-CO-1 GDSC2; CTRP2; CTRP1 4.2106 6.312 3.6359 7.8416
GP5d GDSC2 4.3608 14.1797 -2.2521 18.0282
NCI-H508 GDSC2; CTRP2; CTRP1 4.4979 7.8201 3.1868 9.014
LS513 GDSC2; CTRP2; CTRP1 4.5065 10.6481 1.7916 14.7194
SW948 GDSC2; CTRP2; CTRP1 4.5066 9.0114 2.6054 11.4079
HT115 GDSC2; CTRP2; CTRP1 4.521 5.5904 4.2737 4.5064
DiFi GDSC2 4.5276 6.7593 1.2547 0.813
SNU-81 GDSC2; CTRP2; CTRP1 4.6673 6.8288 3.8296 6.8875
C2BBe1 GDSC2; CTRP2; CTRP1 4.8377 5.8995 4.4425 3.0491
SW1116 GDSC2; CTRP2 4.8569 7.2013 3.806 5.579
CL-11 GDSC2; CTRP2 4.9121 7.5513 3.6791 5.9995
LoVo GDSC2; CTRP2; CTRP1 5.0504 10.1004 2.5311 10.6091
SNU-C2B GDSC2 5.0815 13.3978 -1.3808 12.739
SNU-C2A CTRP2; CTRP1 5.1404 8.6158 3.3479 8.128
COLO 320 CTRP2; CTRP1 5.1636 8.9204 3.2147 7.5428
DLD-1 CTRP2; CTRP1 5.3819 6.4769 4.5977 1.3952
NCI-H747 GDSC2; CTRP2 5.5667 10.4373 2.7699 8.5855
LS1034 GDSC2; CTRP2 5.831 7.9474 4.1845 2.3484
SNU-175 GDSC2; CTRP1 5.9087 16.2722 0.1437 20.1237
HCC-56 CTRP2 6.0333 7.7432 4.4028 1.2823
LS411N GDSC2; CTRP2; CTRP1 6.057 7.3539 4.5977 0.6646
COLO205 GDSC2; CTRP2; CTRP1 6.1705 7.6498 4.5305 0.7864
OUMS-23 CTRP2 6.2774 7.6984 4.5498 0.5968
LS123 GDSC2; CTRP2; CTRP1 6.3723 11.3949 2.9075 6.7821
HCT 8 CTRP2; CTRP1 6.5394 7.8417 4.6241 0.3119
SNU-503 CTRP2 6.6292 9.2657 4.0624 1.8912
MDST8 GDSC2; CTRP2; CTRP1 6.7033 8.0908 4.5983 0.2999
T84 GDSC2; CTRP2 6.7683 10.6773 3.5022 3.8119
SNU-1040 CTRP1 6.8578 8.2776 4.5913 0.5535
SNU-61 GDSC2; CTRP2; CTRP1 6.9914 14.3192 1.9236 9.7367
HT-55 GDSC2; CTRP2; CTRP1 6.9928 12.4579 2.8204 6.2418
RCM-1 [Human ESC] GDSC2; CTRP2; CTRP1 7.0144 8.2616 4.6564 0.1186
HCT 116 GDSC2; CTRP2; CTRP1 7.124 12.4953 2.8887 6.6701
SW1417 GDSC2; CTRP2 7.1687 9.5365 4.2249 0.9362
NCI-H716 GDSC2; CTRP2 7.1839 9.022 4.4327 0.416
COLO201 CTRP2 7.2078 8.7191 4.553 0.1931
SW403 CTRP1 7.2309 9.7233 4.192 2.2226
HCT 15 GDSC2; CTRP2 7.3525 9.4705 4.3332 0.5607
CL-40 CTRP1 7.3744 12.1278 3.217 8.6975
SNU-C1 GDSC2; CTRP2 7.4313 8.9514 4.554 0.144
CCK-81 GDSC2; CTRP2 7.5705 9.5024 4.4104 0.3221
SNU-407 GDSC2; CTRP2 7.5707 9.4143 4.4424 0.2687
CL-34 CTRP1 8.2247 17.3463 1.311 17.7909
HT-29 GDSC2; CTRP2; CTRP1 8.3131 17.2689 1.4064 11.0578
COLO 678 GDSC2; CTRP2; CTRP1 9.4177 18.7135 1.4317 8.3074
⏷ Show the Full List of 62 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 3.398 6.246 0.898 3.8059
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-182 CTRP2 2.3817 4.1898 2.3194 20.7667
JHH-7 GDSC2 2.6317 5.1981 0.8919 5.3771
HLE GDSC2 2.8793 5.1488 1.0842 3.6845
Hep-G2/C3A GDSC2 3.061 5.2449 1.1534 2.9476
Huh-7 GDSC2 3.5142 7.9861 0.1554 7.8686
SNU-398 GDSC2; CTRP2; CTRP1 3.5879 6.0297 3.1136 12.3586
JHH-5 CTRP2 4.1246 7.1435 3.1559 9.9118
HuH-6 CTRP2 4.3382 9.1593 2.3724 12.6516
SNU-761 CTRP2 4.9113 9.061 2.9242 9.1675
Li-7 CTRP2 5.455 7.3111 4.2323 2.6979
Hep-G2 CTRP2; CTRP1 5.8772 7.2074 4.5656 0.9275
JHH-6 GDSC2; CTRP2; CTRP1 6.2801 7.2599 4.7356 0.1859
SNU-886 CTRP2 6.2819 8.2667 4.3102 1.3626
SNU-423 GDSC2; CTRP2 6.4205 9.1489 3.994 2.3601
SNU-878 CTRP2 6.5792 9.9448 3.7245 3.1913
HuH-1 GDSC2; CTRP2 6.7608 8.3496 4.5103 0.4289
JHH-1 GDSC2; CTRP2 6.9429 8.4937 4.5316 0.3088
JHH-4 GDSC2; CTRP2 7.0043 8.5735 4.5268 0.2965
SK-HEP-1 GDSC2; CTRP2 7.0072 8.0696 4.7051 0.0551
Hep 3B2.1-7 GDSC2; CTRP2 7.2173 8.7859 4.5327 0.2214
HLF CTRP2 7.3999 8.6606 4.642 0.0625
SNU-449 GDSC2; CTRP2; CTRP1 7.8699 9.8237 4.4239 0.2457
SNU-387 GDSC2; CTRP2 8.0135 16.5279 1.5487 9.6058
PLC/PRF/5 CTRP2 8.3512 16.7028 1.6868 8.6574
JHH-2 GDSC2; CTRP2 11.2654 24.7424 -0.2293 11.3825
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 224 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1048 GDSC2; CTRP1 1.8493 3.3634 1.8364 24.6935
DMS 273 GDSC2; CTRP2; CTRP1 2.1977 3.5372 2.1867 19.0799
NCI-H1836 GDSC2; CTRP1 2.5215 3.7046 2.5119 19.5194
NCI-H720 GDSC2 2.5558 4.9267 0.97 5.0714
NCI-H2171 GDSC2 2.5597 5.5941 0.6454 7.0736
NCI-H2135 GDSC2 2.5928 7.2471 -0.1473 11.8218
NCI-H82 GDSC2; CTRP1 2.7016 3.9486 2.6841 18.1672
Lu-134-A GDSC2 2.7522 5.5465 0.8077 5.6194
ABC-1 GDSC2 2.7901 7.2424 0.0046 10.4136
ChaGo-K-1 GDSC2; CTRP2; CTRP1 2.8373 4.8151 2.6964 15.2735
NCI-H847 GDSC2 2.8432 7.0045 0.161 9.3468
Ms-1 GDSC2 2.9347 9.1109 -0.8097 14.6727
NCI-H345 GDSC2 2.94 5.5992 0.9106 4.5939
Lu-135 GDSC2 3.0482 6.3507 0.624 6.0848
SCLC-21H CTRP1 3.1034 7.3265 2.0576 34.4886
NCI-H2369 GDSC2 3.1223 12.1657 -2.1805 20.678
NCI-H596 GDSC2; CTRP1 3.1322 4.7192 3.0383 15.1655
NCI-H211 GDSC2; CTRP2 3.1602 7.9872 1.8108 20.3475
NCI-H1770 GDSC2 3.1678 10.8112 -1.4742 17.4325
NCI-H250 GDSC2 3.1722 9.0935 -0.6235 13.0676
A-427 GDSC2 3.2771 6.7842 0.5701 5.9299
NCI-H1993 GDSC2 3.2952 5.5093 1.171 2.469
NCI-H2803 GDSC2 3.3005 9.0169 -0.4925 12.0364
NCI-H290 GDSC2 3.3133 12.5874 -2.243 20.4498
NCI-H2066 GDSC2 3.3565 10.8873 -1.37 16.4613
NCI-H510A GDSC2 3.357 5.2958 1.2984 1.7231
NCI-H1963 GDSC2; CTRP1 3.3642 4.9847 3.2292 13.5541
HARA [Human squamous cell lung carcinoma] GDSC2; CTRP2; CTRP1 3.3651 5.0378 3.2161 11.7936
NCI-H2227 GDSC2 3.3737 10.2113 -1.0247 14.7017
NCI-H522 GDSC2; CTRP2; CTRP1 3.3826 4.99 3.2478 11.6262
LK-2 GDSC2 3.4166 11.6053 -1.6793 17.763
NCI-H2373 GDSC2 3.4288 8.3592 -0.082 9.4215
NCI-H1436 GDSC2 3.4334 6.2121 0.9347 3.5405
NCI-H1581 GDSC2; CTRP2 3.4464 7.0652 2.5172 14.1691
NCI-H358 GDSC2; CTRP2; CTRP1 3.4567 5.658 3.1167 11.8909
EMC-BAC-1 GDSC2 3.5026 10.9387 -1.2873 15.7038
NCI-H2818 GDSC2 3.5047 10.0979 -0.8737 13.6073
SBC-3 GDSC2 3.5078 13.4821 -2.538 21.1352
NCI-H1975 GDSC2; CTRP1 3.5241 7.4971 2.406 16.7063
NCI-H1299 GDSC2; CTRP2; CTRP1 3.53 4.8696 3.438 10.4936
NCI-H2804 GDSC2 3.5514 7.1795 0.5608 5.4507
HCC15 GDSC2; CTRP2; CTRP1 3.5562 5.9673 3.105 11.6562
NCI-H69 GDSC2; CTRP2 3.5598 7.8888 0.2321 6.1356
NCI-H2595 GDSC2 3.5669 10.5797 -1.0644 14.4415
COR-L303 GDSC2 3.5782 5.1144 1.4797 0.6983
NCI-H810 GDSC2; CTRP2; CTRP1 3.5939 5.4181 3.3494 10.624
COR-L311 GDSC2 3.5998 5.6895 1.2562 1.6279
NCI-H1688 GDSC2 3.6397 6.1543 1.0777 2.4575
COR-L32 GDSC2 3.6583 6.2418 1.0496 2.5759
NCI-H2795 GDSC2 3.6818 7.264 0.6026 4.9748
NCI-H2029 GDSC2; CTRP2; CTRP1 3.7269 6.4501 3.0819 11.2878
NCI-H64 GDSC2 3.7464 5.1078 1.5523 0.3605
IST-SL1 GDSC2 3.7558 7.3139 0.6246 4.722
Lu-139 GDSC2 3.7727 5.6762 1.3453 1.0565
SBC-1 GDSC2 3.8038 5.4686 1.4405 0.6727
NCI-H2347 GDSC2 3.8506 11.7934 -1.4532 15.6799
UMC-11 GDSC2 3.8547 6.4531 1.0631 2.2459
NCI-H2722 GDSC2 3.8799 11.4464 -1.263 14.7017
Lu-165 GDSC2 3.914 10.1881 -0.6296 11.395
LB647-SCLC GDSC2 3.9358 5.7327 1.3957 0.7355
NCI-H3255 GDSC2; CTRP1 3.9437 5.1446 3.8174 9.0755
NCI-H740 GDSC2 3.9439 9.2439 -0.1583 8.766
HCC1833 CTRP2; CTRP1 3.9465 5.9463 3.5249 10.3734
COR-L321 GDSC2 3.9637 5.8344 1.3685 0.8112
NCI-H2869 GDSC2 3.9708 6.6248 1.05 2.165
NCI-H3122 GDSC2 3.9728 6.924 0.9227 2.7906
CPC-N GDSC2 4.0371 6.179 1.2658 1.1411
COR-L51 CTRP1 4.0515 9.0721 2.1614 28.3199
NCI-H661 GDSC2; CTRP2; CTRP1 4.0663 7.8592 2.7648 12.5657
Lu-99A GDSC2 4.0787 6.9815 0.9539 2.4966
NCI-H2591 GDSC2 4.0862 9.64 -0.2527 9.001
HCC44 GDSC2; CTRP2; CTRP1 4.169 6.6788 3.4252 10.1448
NCI-H748 GDSC2 4.1733 6.4359 1.2257 1.1817
NCI-H835 GDSC2 4.1899 6.4533 1.2263 1.1653
NCI-H1155 GDSC2; CTRP2 4.204 6.6849 3.4499 8.5227
NCI-H2810 GDSC2 4.2125 6.8826 1.0631 1.8296
HCC1359 CTRP1 4.2207 5.5756 3.9651 13.987
Lu-99 CTRP2; CTRP1 4.2486 5.3408 4.0842 5.9851
NCI-H727 GDSC2; CTRP2; CTRP1 4.2716 5.8714 3.8945 6.6555
LC-2/ad GDSC2 4.275 6.5588 1.2229 1.1077
A-549 GDSC2; CTRP2; CTRP1 4.3406 11.1837 1.3791 16.6871
NCI-H1648 GDSC2 4.3481 17.0397 -3.664 23.0872
NCI-H1105 GDSC2; CTRP2; CTRP1 4.3643 6.7277 3.593 7.6404
EMC-BAC-2 GDSC2 4.3794 12.7838 -1.5608 15.0017
NCI-H2073 CTRP1 4.3866 5.9222 3.9898 12.8346
NCI-H1876 GDSC2; CTRP1 4.4228 6.5587 3.73 8.0079
COLO 668 GDSC2; CTRP2; CTRP1 4.4439 7.9175 3.0895 9.5365
COR-L23 GDSC2; CTRP1 4.4554 5.2212 4.3498 5.0696
NCI-H2342 GDSC2; CTRP2; CTRP1 4.4768 6.7955 3.668 7.0693
NCI-H2106 CTRP2 4.4952 13.6239 0.2888 20.2359
NCI-H2461 GDSC2 4.5302 12.5263 -1.333 13.6216
NCI-H1694 GDSC2; CTRP2; CTRP1 4.55 5.9644 4.1344 4.9896
PaCa-3 GDSC2 4.5836 7.4309 1.0164 1.6595
Calu-3 GDSC2; CTRP2; CTRP1 4.5894 7.7287 3.315 9.5521
LCLC-103H GDSC2; CTRP2; CTRP1 4.5928 6.5443 3.8993 5.8495
RERF-LC-Sq1 GDSC2 4.6145 11.3348 -0.7098 10.3801
NCI-H1650 GDSC2; CTRP2 4.6164 8.4083 2.9937 9.4809
LC-1/sq GDSC2 4.6315 9.7113 0.054 6.348
NCI-H647 GDSC2; CTRP2 4.6453 5.9206 4.2414 4.2338
NCI-H209 GDSC2 4.6509 7.0527 1.195 0.9298
HCC2935 CTRP2; CTRP1 4.6704 6.3458 4.0686 4.9737
NCI-H441 GDSC2; CTRP2; CTRP1 4.6706 6.9855 3.7555 6.2713
HCC1171 CTRP2 4.6795 9.4842 2.5135 13.0942
NCI-H1793 GDSC2; CTRP2; CTRP1 4.6847 7.062 3.7306 6.3438
NCI-H841 GDSC2; CTRP2; CTRP1 4.6912 7.8534 3.3446 7.9404
NCI-H322M GDSC2 4.7069 10.3844 -0.2086 7.6051
NCI-H2731 GDSC2 4.7139 7.7873 0.9334 1.8827
DMS 454 CTRP2 4.7291 7.2869 3.6507 6.4965
NCI-H520 GDSC2; CTRP2 4.747 7.6571 3.4826 7.1624
NCI-H1666 GDSC2; CTRP2; CTRP1 4.7491 11.4156 1.6189 14.8968
NCI-H2087 GDSC2; CTRP2 4.7666 10.4203 2.1216 12.7767
HCC78 GDSC2; CTRP2; CTRP1 4.7687 6.4524 4.1077 4.5915
HCC33 GDSC2; CTRP1 4.7711 6.8241 3.9263 6.1626
NCI-H2009 GDSC2; CTRP2; CTRP1 4.7749 7.0372 3.8241 5.7602
BEN GDSC2; CTRP2; CTRP1 4.809 8.0037 3.3734 7.5745
NCI-H146 GDSC2; CTRP2 4.9294 9.2861 2.827 9.5378
NCI-H2170 GDSC2; CTRP2 4.9305 6.5371 4.2011 3.7709
CAL-12T GDSC2; CTRP2; CTRP1 4.9499 11.8388 1.5777 16.7202
NCI-H1944 GDSC2; CTRP2; CTRP1 4.9825 7.3228 3.8627 5.1724
IST-SL2 GDSC2 5.0013 15.3713 -2.3798 17.1818
HCC4006 CTRP2; CTRP1 5.0105 6.6486 4.2233 3.6032
HCC2108 CTRP2; CTRP1 5.0244 9.3023 2.9084 10.5034
RERF-LC-A1 CTRP2 5.1185 6.9076 4.1738 4.0709
NCI-H1573 GDSC2; CTRP2; CTRP1 5.1784 7.8886 3.7424 5.3021
NCI-H446 GDSC2; CTRP2 5.2193 8.72 3.3502 6.79
SK-MES-1 GDSC2; CTRP2 5.2418 6.8418 4.3044 2.7497
SW1573 GDSC2; CTRP2 5.2737 7.8223 3.8416 4.9605
NCI-H1792 GDSC2; CTRP2; CTRP1 5.32 15.7509 -0.0711 19.8063
NCI-H1437 GDSC2; CTRP1 5.3682 8.9795 3.35 7.6118
NCI-H23 GDSC2; CTRP2; CTRP1 5.4609 7.7592 4.0274 3.6152
VMRC-LCD GDSC2; CTRP2; CTRP1 5.4869 7.3762 4.2347 2.7181
HCC366 GDSC2; CTRP2 5.5567 11.6085 2.1789 11.0263
COR-L47 CTRP2 5.5786 9.6873 3.1517 6.9792
NCI-H2405 GDSC2; CTRP2; CTRP1 5.6429 7.8124 4.1332 2.8951
LUDLU-1 CTRP2 5.6433 11.1756 2.4625 9.7163
NCI-H1915 GDSC2; CTRP2; CTRP1 5.6581 7.5522 4.2693 2.3227
NCI-H2444 GDSC2; CTRP2 5.6667 6.9457 4.5487 1.1447
HOP-62 GDSC2; CTRP2 5.6943 8.9196 3.6181 4.851
COR-L279 GDSC2; CTRP1 5.722 9.1567 3.5329 6.0399
NCI-H2110 GDSC2; CTRP2; CTRP1 5.8026 8.6131 3.857 3.7807
NCI-H650 GDSC2; CTRP2; CTRP1 5.8508 13.41 1.5235 13.1582
NCI-H1568 GDSC2; CTRP2; CTRP1 5.851 11.4201 2.5119 9.2292
NCI-H322 CTRP2 5.8534 8.6963 3.8408 3.6944
NCI-H513 GDSC2 5.8778 17.5916 -2.8489 17.2429
COR-L88 GDSC2; CTRP2; CTRP1 5.9935 10.6034 3.0217 6.9054
COR-L95 GDSC2; CTRP2 6.0358 7.8193 4.3702 1.3971
RERF-LC-Ad1 CTRP2 6.0861 7.3023 4.6201 0.5227
NCI-H460 GDSC2; CTRP2; CTRP1 6.1122 7.3514 4.626 0.5392
DV-90 CTRP2; CTRP1 6.1262 11.1967 2.8277 7.4868
EKVX GDSC2; CTRP2 6.1388 13.0699 1.9032 11.1091
NCI-H526 GDSC2; CTRP2 6.1772 9.3151 3.7633 3.5506
NCI-H1781 GDSC2; CTRP1 6.1926 8.8003 4.0274 2.9662
SBC-5 GDSC2; CTRP2 6.288 10.9864 3.0352 7.2779
MOR/CPR CTRP2 6.308 7.4552 4.6598 0.3427
Sq-1 CTRP2; CTRP1 6.4958 13.1929 2.1184 9.7468
DMS 53 GDSC2; CTRP2 6.5588 11.7757 2.842 6.6956
NCI-H1355 GDSC2; CTRP2; CTRP1 6.5603 10.2285 3.5926 3.7922
HCC827 GDSC2; CTRP2; CTRP1 6.6044 8.5358 4.3769 1.0733
NCI-H226 GDSC2; CTRP2 6.6287 8.1067 4.547 0.4062
LCLC-97TM1 GDSC2; CTRP2; CTRP1 6.6728 8.5586 4.4009 0.8109
NCI-H2122 GDSC2; CTRP2; CTRP1 6.6878 8.211 4.546 0.4205
NCI-H524 GDSC2; CTRP2 6.7115 12.8872 2.4105 8.1883
LC-1/sq-SF CTRP2; CTRP1 6.757 8.2424 4.5634 0.3509
Calu-1 CTRP2 6.7784 8.7504 4.3595 0.8088
LK2 CTRP2 6.7903 7.4647 4.8311 0.0069
PC-14 GDSC2; CTRP2 6.8343 10.9733 3.4057 4.101
Lu-65 GDSC2; CTRP2; CTRP1 6.8557 12.9964 2.4694 7.8136
NCI-H2081 GDSC2; CTRP2; CTRP1 6.8696 15.1167 1.4476 11.7299
NCI-H2196 GDSC2; CTRP2 6.8752 8.4315 4.5272 0.3431
NCI-H196 GDSC2; CTRP2 6.8909 8.3839 4.5513 0.2895
NCI-H2085 GDSC2; CTRP2 6.8913 8.9317 4.3393 0.8501
NCI-H889 CTRP2 6.9071 8.4209 4.5441 0.2975
DMS 114 GDSC2; CTRP2 6.9472 18.881 -0.3592 17.7222
NCI-H2023 GDSC2; CTRP2; CTRP1 6.9593 11.0451 3.4623 3.8031
NCI-H1734 GDSC2; CTRP2 6.9888 8.9169 4.3895 0.6052
NCI-H1184 CTRP2 7.0185 8.7744 4.4574 0.4323
NCI-H2172 GDSC2; CTRP2; CTRP1 7.0214 8.4694 4.5855 0.2178
NCI-H1341 GDSC2; CTRP2 7.0569 8.7019 4.5004 0.3282
EBC-1 GDSC2; CTRP2; CTRP1 7.0615 8.9443 4.4245 0.5259
HCC1195 CTRP2; CTRP1 7.0768 10.9313 3.5851 3.2104
Calu-6 GDSC2; CTRP2; CTRP1 7.0794 8.7815 4.4939 0.3665
DMS 79 GDSC2; CTRP2 7.0884 8.9828 4.4074 0.5919
HCC1588 CTRP2 7.1233 8.4615 4.6123 0.1521
NCI-H838 GDSC2; CTRP2 7.132 8.4028 4.6357 0.1029
NCI-H1092 GDSC2; CTRP2 7.145 8.7072 4.5333 0.2406
SK-LU-1 GDSC2; CTRP2; CTRP1 7.1974 9.37 4.3182 0.7164
NCI-H1930 CTRP1 7.2003 8.5737 4.6155 0.2857
HOP-92 GDSC2; CTRP2 7.2402 13.8353 2.3168 8.9183
NCI-H1435 GDSC2; CTRP2; CTRP1 7.245 8.7059 4.5857 0.1622
HCC1438 CTRP2 7.2487 13.215 2.6177 6.6157
KNS-62 GDSC2; CTRP2; CTRP1 7.3508 10.2165 4.047 1.3814
IA-LM GDSC2; CTRP2 7.3588 8.9116 4.5413 0.1748
T3M-10 CTRP2; CTRP1 7.3739 12.5056 3.0425 4.8971
EPLC-272H GDSC2; CTRP2; CTRP1 7.3789 14.8371 1.9421 9.0972
HCC95 CTRP2 7.4123 8.8721 4.5745 0.1236
RERF-LC-MS GDSC2; CTRP2 7.4259 8.8037 4.6028 0.0926
NCI-H1339 CTRP2 7.4262 8.8562 4.5849 0.1102
NCI-H2228 GDSC2; CTRP2 7.4462 15.1867 1.8084 9.4385
NCI-H1693 GDSC2; CTRP2 7.4767 14.1916 2.3044 7.5142
NCI-H2126 CTRP2; CTRP1 7.5129 8.7415 4.6678 0.0459
RERF-LC-KJ GDSC2; CTRP1 7.5334 10.1888 4.1456 1.1262
RERF-LC-Ad2 CTRP2 7.5654 9.6808 4.3426 0.4515
NCI-H2291 GDSC2; CTRP2 7.6062 9.2175 4.525 0.1463
SW1271 GDSC2; CTRP2 7.615 9.6427 4.3767 0.3681
NCI-H1395 CTRP2 7.6203 15.7165 1.6725 9.6982
NCI-H2141 GDSC2; CTRP2; CTRP1 7.6854 15.0387 2.0515 8.2576
NCI-H2286 CTRP2; CTRP1 7.7528 9.7789 4.3952 0.322
NCI-H1623 GDSC2; CTRP2 7.7928 9.7565 4.4045 0.2688
NCI-H1373 CTRP2; CTRP1 7.8096 9.5482 4.4983 0.1604
SHP-77 GDSC2; CTRP2; CTRP1 7.9096 15.081 2.1777 7.4889
NCI-H1755 GDSC2; CTRP2; CTRP1 7.9726 10.0587 4.379 0.287
HCC2279 CTRP2 8.0067 10.0242 4.3899 0.2756
NCI-H1869 GDSC2; CTRP2 8.0604 9.7967 4.488 0.1146
LXF 289 GDSC2; CTRP2; CTRP1 8.0703 9.9948 4.4378 0.1843
NCI-H1703 GDSC2; CTRP2 8.1354 9.8524 4.4953 0.0988
COLO 699 CTRP2; CTRP1 8.2131 15.5487 2.1517 8.238
NCI-H1563 GDSC2; CTRP2 9.7881 24.6715 -1.1526 15.8109
LOU-NH91 GDSC2; CTRP2 10.2252 20.9801 0.8685 9.1907
COR-L105 GDSC2; CTRP2 10.3309 21.76 0.5737 10.0116
NCI-H292 GDSC2; CTRP2 10.4776 21.8574 0.6186 9.7021
NCI-H2030 GDSC2; CTRP2; CTRP1 10.5091 19.7092 1.6225 7.3494
NCI-H1838 GDSC2; CTRP2 11.2914 32.3447 -3.8155 20.1801
NCI-H1651 GDSC2; CTRP2 13.1929 31.7751 -2.2943 14.6794
Hs 888.Lu CTRP2 7.2392 9.0875 4.4309 0.398
⏷ Show the Full List of 224 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 3.2946 9.7226 -0.8427 13.9477
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 5.9585 11.2936 2.645 8.4298
SYO-1 CTRP2 7.11 8.5412 4.5794 0.1784
P-STS CTRP2 7.2448 8.7346 4.5613 0.1727
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 6.0715 11.7642 2.4973 8.8444
OVKATE GDSC2; CTRP1 2.5977 4.1001 2.5612 19.0394
ES-2 GDSC2 2.8459 7.5534 -0.1071 10.9365
COV434 CTRP2; CTRP1 2.8837 4.2181 2.8508 14.5882
OVCAR-4 GDSC2; CTRP2; CTRP1 3.0796 4.5454 3.0142 13.3967
Caov-4 GDSC2 3.616 9.7145 -0.6075 11.9353
OVCAR-3 GDSC2 3.7291 10.9523 -1.1297 14.3911
TYK-nu GDSC2; CTRP2; CTRP1 3.949 5.956 3.5235 8.9664
COV644 CTRP2; CTRP1 4.2114 9.6845 2.0067 14.4948
IGROV-1 GDSC2; CTRP2; CTRP1 4.2804 6.2541 3.7323 7.2792
OV-90 GDSC2; CTRP2; CTRP1 4.5312 6.1481 4.0299 5.4592
OVK18 GDSC2; CTRP2; CTRP1 4.6451 11.398 1.5383 15.4263
COV362 CTRP2; CTRP1 4.6649 6.3665 4.0534 5.0488
SNU-119 CTRP2 4.681 11.528 1.495 17.6731
OVCAR-5 GDSC2; CTRP2 4.9432 7.5134 3.7246 5.746
ONCO-DG-1 CTRP2 4.9985 6.7324 4.1618 3.7992
A2780 GDSC2; CTRP2; CTRP1 5.1182 7.2759 3.9994 4.3362
TOV-112D GDSC2; CTRP2 5.3425 10.4575 2.5821 9.767
OAW42 GDSC2; CTRP2; CTRP1 5.9409 12.549 2.021 11.0534
ES2 CTRP2 5.9988 7.7523 4.3789 1.6252
EFO-27 GDSC2; CTRP2; CTRP1 6.1607 8.6903 4.0587 2.4904
Kuramochi GDSC2; CTRP2 6.4229 9.3463 3.9048 2.692
OV7 CTRP2; CTRP1 6.4447 8.082 4.4865 0.7178
OV56 GDSC2; CTRP2 6.6238 7.6549 4.7111 0.1062
COV318 CTRP1 6.6409 7.7781 4.6881 0.3398
DOV13 GDSC2; CTRP2 6.6764 12.2114 2.713 8.09
SNU-8 CTRP2 6.7128 7.8809 4.6645 0.1503
TOV-21G GDSC2; CTRP2 6.7776 8.1805 4.581 0.2728
OVISE GDSC2; CTRP2 6.8403 8.3972 4.5257 0.4157
SNU-840 CTRP2; CTRP1 6.9384 15.5116 1.3041 12.1529
OVSAHO CTRP2 6.9439 8.7128 4.4492 0.4842
OVMANA CTRP1 7.0103 8.709 4.4926 0.8511
OC 314 GDSC2; CTRP2 7.0644 11.3763 3.3616 3.9914
HEY A8 CTRP2; CTRP1 7.1154 8.5066 4.6078 0.1607
JHOC-5 CTRP2; CTRP1 7.1342 8.496 4.6185 0.1648
JHOM-1 CTRP2; CTRP1 7.2341 8.3598 4.7001 0.0485
FU-OV-1 GDSC2; CTRP2 7.269 9.0065 4.4729 0.3289
Caov-3 GDSC2; CTRP2; CTRP1 7.3022 9.1642 4.442 0.3861
JHOS-4 GDSC2; CTRP1 7.3302 9.118 4.4703 0.3719
JHOS-2 GDSC2; CTRP2 7.4107 8.9362 4.5517 0.1507
EFO-21 GDSC2; CTRP2; CTRP1 7.4775 8.9991 4.5684 0.1381
OVTOKO GDSC2; CTRP2 7.5939 9.4275 4.4465 0.256
RMG-I GDSC2; CTRP2; CTRP1 7.6593 17.8312 0.6887 13.2262
MCAS CTRP2 7.6869 9.2444 4.5446 0.1122
OAW28 GDSC2; CTRP2 7.7379 9.6324 4.428 0.2473
SK-OV-3 GDSC2; CTRP2; CTRP1 7.8944 9.5133 4.5404 0.1034
OVCAR-8 GDSC2; CTRP2; CTRP1 7.9387 9.4764 4.5681 0.0754
RMUG-S CTRP1 7.9752 15.4973 2.024 14.7488
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 6.6944 7.8129 4.6817 0.1301
Yamato-SS CTRP2 6.6958 8.0796 4.5854 0.2942
EW-8 GDSC2 2.8672 5.371 0.9709 4.3829
SW872 GDSC2 3.0298 6.9423 0.3256 7.9184
Hs 633.T GDSC2 3.2881 8.5003 -0.2492 10.6978
MFH-ino GDSC2 3.4658 5.5776 1.2345 1.899
SW684 GDSC2 3.4895 6.229 0.96 3.3083
Rh30 GDSC2 3.5858 6.1174 1.0644 2.6025
RKN GDSC2; CTRP2; CTRP1 3.9479 5.3405 3.7593 8.0687
TE 441.T GDSC2; CTRP2 4.1618 6.0477 3.6987 7.6281
VA-ES-BJ GDSC2 4.2313 6.3159 1.2983 0.8656
A-204 GDSC2; CTRP2 4.7594 8.1696 3.2384 8.1593
MES-SA GDSC2 4.8915 13.2966 -1.4583 13.4693
Hs 729.T CTRP2 4.9025 6.8139 4.0387 4.5094
GCT GDSC2; CTRP2 5.141 7.6538 3.8193 4.9663
STS-0421 GDSC2 5.3156 7.5526 1.2749 0.3862
HT-1080 GDSC2; CTRP2; CTRP1 5.7883 7.9305 4.176 2.5144
TE 617.T CTRP2 5.8179 10.3687 2.9962 7.2199
BT-12 CTRP2 6.2378 6.9606 4.8121 0.0574
SW982 GDSC2; CTRP2 6.324 8.6448 4.1656 1.8342
BT-16 CTRP2 7.1113 8.3532 4.6453 0.096
Rh18 CTRP2 7.1609 8.9455 4.452 0.3854
SK-LMS-1 GDSC2; CTRP2 7.177 10.01 4.0329 1.5034
Rh41 GDSC2; CTRP2 7.2019 8.9674 4.4605 0.3532
Tm87-16 CTRP2 7.2485 17.2331 0.675 13.8466
KYM-1 GDSC2; CTRP2 8.0876 15.3813 2.1385 7.3422
G-401 GDSC2; CTRP2; CTRP1 8.1023 16.2622 1.7453 8.8344
G-402 GDSC2; CTRP2 8.787 11.0785 4.3072 0.1894
SK-UT-1 GDSC2; CTRP2 9.0561 17.345 1.8288 7.2924
TTC-709 CTRP2 10.3993 23.1844 -0.0459 11.8458
RD GDSC2; CTRP2 12.4251 25.5352 0.1 9.2085
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 7.3136 17.1335 0.7708 13.4118
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC2; CTRP2; CTRP1 5.2241 9.9952 2.727 9.4651
MPP 89 GDSC2; CTRP2 6.9334 9.0084 4.3279 0.7985
NCI-H2052 GDSC2; CTRP2; CTRP1 7.1281 9.1754 4.3638 0.6845
JL-1 CTRP2 7.1485 8.2587 4.6903 0.0519
IST-Mes1 GDSC2; CTRP2 7.1901 8.8949 4.4826 0.3155
ACC-MESO-1 CTRP2 7.2739 8.4393 4.6728 0.0524
NCI-H2452 GDSC2; CTRP2 7.5038 15.231 1.8263 9.2892
MSTO-211H GDSC2; CTRP2; CTRP1 7.5351 9.444 4.4319 0.3483
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PC-3 GDSC2 3.3084 6.0853 0.9174 3.8526
NCI-H660 GDSC2; CTRP2 3.5981 5.3011 3.3892 10.3781
DU145 GDSC2; CTRP2 5.966 10.1914 3.1927 6.1718
PaCa-3 CTRP2; CTRP1 6.8551 8.0318 4.6784 0.1225
VCaP GDSC2; CTRP2 7.1925 8.6268 4.5799 0.159
LNCaP clone FGC GDSC2; CTRP2 7.7332 9.9139 4.324 0.4262
22Rv1 GDSC2; CTRP2 7.929 9.935 4.3924 0.2917
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 3.3716 8.8867 -0.3781 11.2325
YD-15 CTRP2 6.6955 14.2274 1.7457 10.8092
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 2.2805 10.848 -2.1925 23.0104
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-39 GDSC2 1.8494 10.03 -2.1412 24.0755
SCH GDSC2 2.5762 14.2652 -3.6593 27.2962
AGS GDSC2; CTRP2; CTRP1 2.8099 5.4811 2.4775 18.6298
TGBC11TKB GDSC2 2.9679 5.7504 0.8572 4.856
TMK-1 GDSC2 3.0492 5.3852 1.0814 3.3799
RF-48 GDSC2 3.3243 12.0873 -1.987 19.3522
GCIY GDSC2 3.4403 11.373 -1.5471 17.0955
MKN28 GDSC2 3.5052 9.4889 -0.5763 12.0191
OCUM-1 GDSC2 3.5883 6.3524 0.9616 3.1437
RERF-GC-1B GDSC2 3.6055 11.158 -1.3196 15.615
GSS CTRP2 3.9675 6.6441 3.2339 9.9804
SK-GT-2 GDSC2 4.012 8.494 0.2373 6.4305
MKN1 GDSC2; CTRP2 4.0936 6.7648 3.3038 9.3854
ECC10 GDSC2; CTRP2 4.1703 6.8708 3.3295 9.0941
SNU-16 GDSC2; CTRP2 4.2798 5.8033 3.9268 6.4177
Hs 746.T GDSC2; CTRP2 5.3342 6.9996 4.2966 2.6264
HGC-27 GDSC2; CTRP2 5.3579 7.9502 3.8437 4.4733
GSU CTRP2 5.8012 6.6906 4.7338 0.3867
MKN45 GDSC2; CTRP2 5.9034 6.8001 4.7374 0.3127
KATO III GDSC2; CTRP2 6.272 11.3119 2.8654 7.0311
ECC12 GDSC2; CTRP2 6.4925 7.9405 4.552 0.4626
SNU-620 CTRP2 6.5359 7.6748 4.6707 0.1891
SNU-5 GDSC2; CTRP2 7.1269 16.4597 0.9656 13.0178
SNU-668 CTRP2 7.2349 8.4322 4.6618 0.0646
23132/87 GDSC2; CTRP2 7.2781 8.7416 4.5712 0.1525
SH-10-TC CTRP2; CTRP1 7.2952 11.0207 3.6708 2.674
SNU-601 CTRP2 7.297 8.8213 4.5502 0.1763
NUGC-3 GDSC2; CTRP2 7.3105 8.8774 4.5354 0.194
SNU-719 CTRP2 7.345 9.0292 4.4943 0.2867
HuG1-N CTRP2 7.3761 9.3697 4.3814 0.4459
SNU-1 GDSC2; CTRP2 7.7205 12.8256 3.093 4.2438
Fu97 GDSC2; CTRP1 7.7751 9.3256 4.5623 0.1142
IM95 GDSC2; CTRP2 7.8044 14.0677 2.573 6.0761
MKN74 CTRP2; CTRP1 7.8528 9.9614 4.3679 0.3384
NUGC-4 GDSC2; CTRP2; CTRP1 8.1744 16.0542 1.8902 9.3415
MKN7 GDSC2; CTRP2; CTRP1 8.4298 15.9801 2.0865 7.1746
KE-39 CTRP2 8.5415 16.6165 1.8482 7.836
SNU-216 CTRP2 9.0441 21.0473 0.0808 13.1851
NCI-N87 GDSC2; CTRP2 10.2918 29.8442 -3.3013 20.3606
LMSU CTRP2 10.9888 19.747 1.8564 5.2529
SNU-685 CTRP2 6.8898 8.1275 4.6434 0.1392
SNU-1077 CTRP2 7.3077 9.075 4.4631 0.312
SNG-M GDSC2; CTRP2; CTRP1 7.8839 9.4949 4.5429 0.1024
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC2 2.4265 9.2428 -1.2724 18.4384
KMH-2 GDSC2 3.0468 9.0859 -0.7129 13.8655
HTC-C3 GDSC2 3.4871 12.2257 -1.9326 18.7151
ASH-3 GDSC2 3.4996 5.3997 1.3275 1.4108
CAL-62 GDSC2 3.7326 5.3627 1.4507 0.6877
K5 GDSC2 4.3327 6.3296 1.3358 0.6748
WRO GDSC2 4.3687 13.3423 -1.8389 16.2696
8505C GDSC2; CTRP2 4.6174 6.8021 3.7885 7.1137
SW579 CTRP2 5.5163 6.908 4.4705 1.6391
CGTH-W-1 GDSC2; CTRP2 6.8473 8.7336 4.3983 0.6606
FTC-133 GDSC2; CTRP2 6.9594 8.2624 4.6217 0.1534
TT GDSC2; CTRP2 7.0545 8.6094 4.5335 0.3087
B-CPAP GDSC2; CTRP2 7.0623 8.509 4.5728 0.2001
8305C GDSC2; CTRP2 7.1243 14.9645 1.6926 10.348
FTC-238 CTRP2 7.1922 8.2699 4.7013 0.0407
ML-1 [Human leukemia] GDSC2; CTRP2 7.4494 9.6519 4.3051 0.5803
BHT-101 GDSC2; CTRP2 7.6066 9.219 4.5246 0.1467
TT2609-C02 GDSC2; CTRP2 11.6614 22.3767 1.0735 7.0606
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHU-011 GDSC2 2.8631 9.0922 -0.855 15.1
HO-1-u-1 GDSC2 2.9184 7.3519 0.0456 9.8549
OSC-19 GDSC2 3.0576 10.0847 -1.1983 16.3697
SCC-15 GDSC2 3.0812 8.6792 -0.487 12.5354
UPCI-SCC-090 GDSC2 3.2469 9.6854 -0.8595 14.153
OSC-20 GDSC2 3.4236 7.4581 0.3467 6.9428
Ca9-22 GDSC2 3.4473 6.9824 0.5869 5.4967
DOK GDSC2 3.5403 12.5167 -2.0364 19.0304
SCC-25 GDSC2 3.5662 7.9127 0.2249 7.3593
BICR 78 GDSC2 3.5858 10.0768 -0.8052 13.0587
SAT [Human HNSCC] GDSC2 3.7212 9.6981 -0.5262 11.2596
JHU-029 GDSC2 3.7477 15.8048 -3.5055 23.9381
KOSC-2 GDSC2 3.8123 12.8228 -1.9853 18.1625
KON GDSC2 3.8406 13.3842 -2.2405 19.1623
SAS GDSC2 3.9122 18.7189 -4.8242 27.2469
HO-1-N-1 GDSC2 3.9892 5.9687 1.3274 0.9427
SKN-3 GDSC2 4.067 7.0223 0.9303 2.6277
PCI-06A GDSC2 4.0807 13.0587 -1.9058 17.2011
NCI-H3118 GDSC2 4.2483 8.9735 0.1612 6.4273
BICR 10 GDSC2 4.2965 6.1714 1.3801 0.5616
HSC-2 GDSC2; CTRP2; CTRP1 4.3391 7.0499 3.4144 8.4313
PCI-04B GDSC2 4.3564 6.9641 1.0986 1.5319
PCI-30 GDSC2 4.3707 11.3464 -0.8757 11.7112
BB30-HNC GDSC2 4.4364 18.7579 -4.4453 25.1545
LB771-HNC GDSC2 4.5253 7.5635 0.9345 2.0698
YD-8 CTRP2 4.5279 6.5525 3.8261 6.2136
PCI-15A GDSC2 4.5362 6.4537 1.3716 0.4663
HSC-4 GDSC2; CTRP2 4.9486 7.4234 3.7742 5.5268
FaDu GDSC2; CTRP2 5.1236 14.6996 0.2827 18.9664
JHU-022 GDSC2 5.7143 21.5458 -4.8769 23.765
SCC-4 GDSC2; CTRP2 5.7708 10.8917 2.7019 8.5121
PE/CA-PJ41 (clone D2) CTRP2 6.4367 11.9555 2.6692 7.5712
PE/CA-PJ49 CTRP2 6.8368 7.9049 4.7014 0.0801
BICR 6 CTRP2 6.8776 8.0935 4.6508 0.1319
BICR 18 CTRP2 6.881 9.0205 4.2983 0.916
CAL-27 GDSC2; CTRP2 6.9565 8.5186 4.5279 0.3112
SNU-1066 CTRP2 7.3009 12.954 2.7749 5.9414
BICR 16 CTRP2 7.3248 8.5004 4.6698 0.0499
HSC-3 GDSC2; CTRP2 7.3429 8.7259 4.6 0.1074
Detroit 562 GDSC2; CTRP2 7.3681 8.8385 4.5703 0.1363
PE/CA-PJ34 (clone C12) CTRP2 7.4481 10.3373 4.0313 1.3057
SNU-899 CTRP2 7.4488 8.609 4.6756 0.0368
BICR 22 GDSC2; CTRP2 7.49 8.937 4.5799 0.1058
CAL-33 GDSC2; CTRP2 7.5478 9.3289 4.4643 0.2407
SNU-46 CTRP2 7.7728 9.6735 4.4265 0.2409
SNU-1041 CTRP2 7.8885 10.0332 4.3417 0.3437
SNU-1214 CTRP2 7.9827 10.0361 4.3767 0.2628
YD-10B CTRP2 8.3223 17.732 1.1805 10.5014
SCC-9 GDSC2; CTRP2; CTRP1 8.4059 18.1792 1.0347 10.9575
PE/CA-PJ15 GDSC2; CTRP2 8.479 16.4995 1.8635 7.8582
BICR 56 CTRP2 8.9437 18.0275 1.4433 8.7751
BICR 31 GDSC2; CTRP2 11.0983 23.8896 0.0617 10.7126
BHY GDSC2; CTRP2 11.828 26.1551 -0.5361 11.6348
SNU-1076 CTRP2 14.9585 35.6576 -3.0011 14.4909
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW780 GDSC2 3.3685 5.6962 1.1293 2.5807
HT-1197 CTRP2 3.7283 6.5622 3.0281 11.4129
TCCSUP GDSC2; CTRP2 4.6325 7.134 3.6392 7.7909
HT-1376 GDSC2; CTRP2; CTRP1 4.7335 9.7307 2.4465 11.5905
U-BLC1 CTRP2 4.7877 13.9438 0.379 19.3176
639V GDSC2; CTRP2 5.3145 6.8879 4.3369 2.4912
CAL-29 GDSC2; CTRP2 5.867 7.5882 4.3751 1.5658
BFTC-905 GDSC2; CTRP2 6.0011 7.6946 4.4061 1.3037
BC-3C CTRP2 6.0574 10.6797 3.0199 6.7356
5637 GDSC2; CTRP2; CTRP1 6.4051 11.3602 2.9474 7.5647
253J-BV CTRP2 6.4813 7.8566 4.5798 0.4001
KU-19-19 GDSC2; CTRP2 6.6593 8.0574 4.5787 0.3224
VM-CUB-1 CTRP2 6.9305 13.1755 2.4231 7.8164
RT-112 GDSC2; CTRP2 6.9351 8.3024 4.5983 0.194
253J CTRP2 6.9651 8.251 4.6279 0.1437
UM-UC-1 CTRP2 7.2626 8.9991 4.4731 0.3088
647V GDSC2; CTRP2 7.2633 8.5358 4.6367 0.0828
JMSU-1 CTRP2 7.3156 8.6356 4.6211 0.0903
SW1710 GDSC2; CTRP2 7.5481 9.3244 4.466 0.238
UM-UC-3 GDSC2; CTRP2; CTRP1 8.109 13.8982 2.8481 4.7734
KMBC-2 CTRP2; CTRP1 8.2324 13.561 3.0705 3.8518
RT-4 GDSC2; CTRP2; CTRP1 8.8113 17.2609 1.7294 7.993
T24 GDSC2; CTRP2 9.1477 19.0115 1.1126 9.662
SCaBER CTRP2 12.2834 24.7959 0.3497 8.6254
J82 GDSC2; CTRP2 13.4915 28.9938 -0.8383 10.7437
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JAR GDSC2 2.1781 5.6651 0.3137 10.1435
JEG-3 GDSC2 2.5418 6.6177 0.1257 10.3179
C-33 A GDSC2 2.666 7.0913 -0.0142 10.8397
SW954 GDSC2 2.7308 4.7254 1.1876 3.3664
TC-YIK GDSC2 2.8501 9.6081 -1.1209 16.5187
C-4-I GDSC2 2.8817 8.2406 -0.4194 12.6534
OV17R GDSC2 2.9285 8.3024 -0.4148 12.5093
JHOS-3 GDSC2 3.0047 9.9947 -1.194 16.4842
SiSo GDSC2 3.1757 9.5673 -0.8541 14.2997
NEC8 GDSC2 3.1803 5.239 1.2263 2.3483
UWB1.289 GDSC2 3.1932 7.0386 0.3924 7.1578
HT-3 GDSC2 3.2088 6.4492 0.6841 5.3951
OVCA433 GDSC2 3.2613 6.6128 0.641 5.544
SKG-IIIa GDSC2 3.2974 6.4485 0.7417 4.8845
NT2-D1 GDSC2 3.4945 9.7716 -0.7217 12.828
OMC-1 [Human cervical carcinoma] GDSC2 3.5147 5.74 1.1904 2.0552
NCC-IT GDSC2 3.5261 8.9123 -0.2817 10.3412
OVCA420 GDSC2 3.5618 14.8815 -3.19 23.3474
KGN GDSC2 3.5754 8.5324 -0.0648 9.0051
HEY GDSC2 3.6309 8.1305 0.1641 7.5782
DoTc2 4510 GDSC2 3.6394 5.5788 1.3218 1.2849
CAL-39 GDSC2 3.6683 16.6787 -3.9996 25.6078
HEC-1 GDSC2 3.6911 5.4551 1.3961 0.9251
SKN GDSC2 3.7222 6.5756 0.938 3.0669
BPH-1 GDSC2 3.8189 10.5367 -0.864 12.8349
OVMIU GDSC2 3.8392 7.6919 0.5016 5.2639
SW962 GDSC2 3.8525 6.5677 1.0126 2.4988
SW756 GDSC2 3.8671 5.5281 1.4447 0.616
LB831-BLC GDSC2 3.8954 7.1035 0.8011 3.5329
DSH1 GDSC2 4.0107 5.975 1.3344 0.8998
Ca Ski GDSC2 4.3291 13.5066 -1.9467 16.8232
PA-1 GDSC2 4.3465 6.1063 1.4237 0.4182
PWR-1E GDSC2 4.3818 6.2761 1.3756 0.5296
ACC-OV7 GDSC2 4.4601 12.319 -1.2812 13.5216
ME-180 GDSC2 4.7843 14.87 -2.2882 17.2656
PEO1 GDSC2 5.0413 15.3926 -2.3624 17.0315
SiHa GDSC2 5.3985 16.8347 -2.8117 18.0259
MS751 GDSC2 5.7867 20.0838 -4.1135 21.5388
HeLa GDSC2; CTRP2 6.2814 7.3208 4.6995 0.2225
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 The Sir2 family of protein deacetylases. Annu Rev Biochem. 2004;73:417-35.
2 Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science. 2007 Jul 27;317(5837):516-9.