Details of the Drug

General Information of Drug (ID: DM32FKD)

Drug Name
PF-228
Synonyms
869288-64-2; PF-573228; PF 573228; PF573228; PF-228; CHEMBL514554; 3,4-Dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone; 6-((4-((3-(Methylsulfonyl)benzyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-3,4-dihydroquinolin-2(1H)-one; 6-(4-(3-(methylsulfonyl)benzylamino)-5-(trifluoromethyl)pyrimidin-2-ylamino)-3,4-dihydroquinolin-2(1H)-one; 6-[4-(3-Methanesulfonyl-benzylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]-3,4-dihydro-1H-quinolin-2-one
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 491.5
Logarithm of the Partition Coefficient (xlogp) 3.2
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 10
Chemical Identifiers
Formula
C22H20F3N5O3S
IUPAC Name
6-[[4-[(3-methylsulfonylphenyl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-3,4-dihydro-1H-quinolin-2-one
Canonical SMILES
CS(=O)(=O)C1=CC=CC(=C1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)CC4
InChI
InChI=1S/C22H20F3N5O3S/c1-34(32,33)16-4-2-3-13(9-16)11-26-20-17(22(23,24)25)12-27-21(30-20)28-15-6-7-18-14(10-15)5-8-19(31)29-18/h2-4,6-7,9-10,12H,5,8,11H2,1H3,(H,29,31)(H2,26,27,28,30)
InChIKey
HESLKTSGTIBHJU-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
11612883
ChEBI ID
CHEBI:91446
CAS Number
869288-64-2
TTD ID
D02QAZ
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cyclin-dependent kinase 1 (CDK1) TTH6V3D CDK1_HUMAN Inhibitor [1]
Cyclin-dependent kinase 2 (CDK2) TT7HF4W CDK2_HUMAN Inhibitor [1]
Cyclin-dependent kinase 7 (CDK7) TTQYF7G CDK7_HUMAN Inhibitor [1]
Focal adhesion kinase 1 (FAK) TTON5IT FAK1_HUMAN Inhibitor [1]
Glycogen synthase kinase-3 beta (GSK-3B) TTRSMW9 GSK3B_HUMAN Inhibitor [1]
Inhibitor of nuclear factor kappa-B kinase beta (IKKB) TTJ3E9X IKKB_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Focal adhesion kinase 1 (PTK2) OT3Q1JDY FAK1_HUMAN Post-Translational Modifications [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Glycogen synthase kinase-3 beta (GSK-3B) DTT GSK3B 1.26E-01 -0.23 -0.77
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 145 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 2.3141 4.3758 2.2795 24.9679
JK1 CTRP2 2.5245 4.8328 2.4533 23.6912
JM1 CTRP2 2.6643 4.7971 2.6064 22.7143
MV4-11 CTRP2 -4.5203 0.2803 -4.5548 68.7107
MOLM-13 CTRP2 -2.4968 -0.6991 -2.4969 56.9011
EoL-1 CTRP2 0.5297 2.1198 0.5289 36.7423
SEM CTRP2 0.5588 2.9864 0.5435 36.5954
NALM-6 CTRP2 0.5793 2.1369 0.5787 36.4114
KMS-26 CTRP2 0.634 2.0815 0.6337 36.0459
Peer CTRP2 0.8637 2.2881 0.8633 34.516
NCI-H929 CTRP2 0.9952 3.3868 0.9744 33.7072
AML-193 CTRP2 1.0394 3.7892 0.9943 33.4926
Pfeiffer CTRP2 1.0395 3.1813 1.0281 33.3814
KMS-11 CTRP2 1.0974 3.9343 1.0426 33.1388
EM-2 CTRP2 1.2997 2.8586 1.298 31.6155
OCI-AML-3 CTRP2 1.4199 2.0634 1.4199 30.8093
F-36P CTRP2 1.6344 5.12 1.4489 30.0026
Mino CTRP2 1.6844 2.2163 1.6844 29.047
Ri-1 CTRP2 1.6994 5.0932 1.5243 29.5362
697 CTRP2 1.8248 2.7826 1.8247 28.1118
ST486 CTRP2 1.8268 2.6696 1.8267 28.0986
KE-97 CTRP2 1.8299 4.4612 1.761 28.3096
SU-DHL-6 CTRP2 1.8355 4.7642 1.7268 28.4071
WSU-DLCL2 CTRP2 1.8394 3.6775 1.8284 28.051
RS4;11 CTRP2 1.8553 3.0344 1.8549 27.9098
OPM-2 CTRP2 1.8562 2.7585 1.8562 27.9025
NU-DUL-1 CTRP2 1.8724 3.9851 1.8476 27.8776
KMS-34 CTRP2 1.9132 3.0441 1.9128 27.5238
SUP-M2 CTRP2 1.9179 2.9787 1.9177 27.492
OCI-AML-2 CTRP2 1.9422 3.2843 1.9407 27.3344
OCI-Ly19 CTRP2 1.9514 4.1647 1.9174 27.3821
RPMI-8402 CTRP2 1.9773 3.3528 1.9755 27.1016
OCI-AML-5 CTRP2 1.9967 2.9873 1.9966 26.9665
PF-382 CTRP2 2.0715 4.4972 2.0127 26.6662
MOLM-16 CTRP2 2.1016 3.7729 2.0931 26.2957
MHH-CALL-4 CTRP2 2.1198 10.6164 0.0117 32.6886
Kasumi-1 CTRP2 2.1304 3.647 2.1257 26.0911
PL21 CTRP2 2.1509 4.1691 2.1248 26.0265
SIG-M5 CTRP2 2.1542 2.9612 2.1542 25.9173
SKM-1 CTRP2 2.1624 3.0894 2.1623 25.8629
Mono-Mac-1 CTRP2 2.1674 9.618 0.4951 31.2477
P31/FUJ CTRP2 2.1902 3.6924 2.1853 25.6936
SET-2 CTRP2 2.2078 4.1042 2.1878 25.6269
KMS-21-BM CTRP2 2.2187 4.0621 2.2014 25.5452
MOLT-3 CTRP2 2.2397 3.5672 2.2374 25.3551
NB4 CTRP2 2.2425 3.2201 2.2423 25.3296
NU-DHL-1 CTRP2 2.246 5.117 2.1105 25.7669
GA-10 CTRP2 2.2473 3.4159 2.2464 25.2998
NOMO-1 CTRP2 2.3369 6.85 1.7527 26.7281
RCH-ACV CTRP2 2.3515 5.5775 2.1315 25.3586
U-937 CTRP2 2.3807 3.8765 2.3745 24.4287
THP-1 CTRP2 2.3816 4.5074 2.3387 24.5464
HuT 78 CTRP2 2.3943 4.5161 2.3512 24.4627
TF-1 CTRP2 2.3983 4.043 2.3869 24.3287
SUP-HD1 CTRP2 2.4365 4.0654 2.4252 24.0743
MOLT-16 CTRP2 2.4374 3.0505 2.4374 24.0305
L-540 CTRP2 2.4424 4.4737 2.4055 24.1211
Daudi CTRP2 2.4501 4.6581 2.3954 24.1306
P12-Ichikawa CTRP2 2.4522 3.0841 2.4522 23.9316
BV-173 CTRP2 2.4682 5.0101 2.3676 24.1673
L-363 CTRP2 2.4722 3.9366 2.466 23.8191
A3/Kawakami CTRP2 2.5002 3.7216 2.4984 23.6179
KE-37 CTRP2 2.5059 3.3182 2.5059 23.5741
Jurkat CTRP2 2.5144 4.3993 2.4869 23.6096
SU-DHL-8 CTRP2 2.5268 4.9159 2.4445 23.7139
Kasumi-2 CTRP2 2.5356 4.9699 2.446 23.6802
HL-60 CTRP2 2.5835 4.6723 2.5349 23.2209
MOLT-13 CTRP2 2.5879 4.3456 2.5669 23.098
M-07e CTRP2 2.5885 6.1955 2.2305 24.2714
JJN-3 CTRP2 2.6063 3.6401 2.6056 22.9075
KMS-20 CTRP2 2.6085 3.7886 2.6067 22.8964
DEL CTRP2 2.6327 3.3371 2.6327 22.7294
MM1.S CTRP2 2.6414 4.0881 2.6339 22.6961
DND-41 CTRP2 2.6944 4.8708 2.6293 22.5388
SU-DHL-10 CTRP2 2.7011 3.4146 2.7011 22.2733
Ki-JK CTRP2 2.7294 4.5566 2.6991 22.187
KMS-12-BM CTRP2 2.7322 4.2237 2.722 22.1004
MC116 CTRP2 2.7427 3.2186 2.7427 21.9961
KCL-22 CTRP2 2.7451 4.4964 2.7201 22.0644
BL-70 CTRP2 2.7645 4.1538 2.7575 21.8748
Ci-1 CTRP2 2.8001 5.4198 2.6527 22.12
KO52 CTRP2 2.8578 4.8303 2.8076 21.3991
Namalwa CTRP2 2.8684 4.8862 2.8123 21.3486
RPMI-8226 CTRP2 2.905 4.6783 2.8727 21.0237
TALL-1 [Human adult T-ALL] CTRP2 2.9195 6.3509 2.5458 22.1324
SUP-T1 CTRP2 2.9857 5.6797 2.7984 21.0248
HEL CTRP2 2.9937 4.8447 2.9498 20.4724
SU-DHL-4 CTRP2 3 5.6734 2.8154 20.9201
Karpas-299 CTRP2 3.0483 5.2219 2.9569 20.2718
KMS-18 CTRP2 3.1065 5.6817 2.9295 20.1843
MOLM-6 CTRP2 3.1387 5.855 2.923 20.1074
KMS-27 CTRP2 3.1435 5.1098 3.0761 19.555
HT CTRP2 3.1827 4.6229 3.1663 19.12
DB CTRP2 3.2588 5.4548 3.1427 18.9558
EB1 CTRP2 3.2666 5.4494 3.1522 18.8979
CA46 CTRP2 3.2977 5.0277 3.251 18.4565
EHEB CTRP2 3.3428 6.1117 3.0775 18.928
U266B1 CTRP2 3.348 6.0491 3.1004 18.8294
MOTN-1 CTRP2 3.3485 5.857 3.1513 18.6455
KMS-28BM CTRP2 3.3663 5.8758 3.166 18.5381
MOLP-8 CTRP2 3.3749 5.4407 3.2709 18.1408
Hs 611.T CTRP2 3.3857 5.389 3.2919 18.0332
JeKo-1 CTRP2 3.4227 5.2073 3.3607 17.6764
AMO1 CTRP2 3.4479 4.9874 3.4143 17.4115
LP-1 CTRP2 3.4598 4.9629 3.4292 17.3219
KM-H2 CTRP2 3.4639 5.3703 3.3795 17.4796
CML-T1 CTRP2 3.4741 5.732 3.3181 17.6629
HH [Human lymphoma] CTRP2 3.5034 5.9608 3.2937 17.6596
HPB-ALL CTRP2 3.5348 5.3517 3.4589 16.9782
Karpas-422 CTRP2 3.5542 5.5132 3.4512 16.9427
SR CTRP2 3.5703 5.5057 3.47 16.8262
HDLM-2 CTRP2 3.611 6.0248 3.3941 16.9697
SU-DHL-1 CTRP2 3.6531 5.2155 3.6055 16.0922
RPMI-6666 CTRP2 3.6737 5.2958 3.6165 15.9883
SUP-T11 CTRP2 3.7267 5.9988 3.5274 16.1365
JURL-MK1 CTRP2 3.7739 5.4887 3.6932 15.4022
EJM CTRP2 3.8278 6.0813 3.6152 15.5122
LAMA-84 CTRP2 3.8434 5.6991 3.7271 15.0641
SUP-B15 CTRP2 3.8698 5.713 3.7528 14.8906
Ku812 CTRP2 3.8725 5.9446 3.7006 15.068
HEL 92.1.7 CTRP2 3.9693 6.7549 3.5526 15.3259
JVM-2 CTRP2 4.0114 6.1005 3.8101 14.25
KYO-1 CTRP2 4.0378 6.1303 3.8305 14.0963
MOLP-2 CTRP2 4.0506 5.783 3.9339 13.6862
CMK CTRP2 4.1187 6.5109 3.7992 13.9711
Mono-Mac-6 CTRP2 4.2483 17.7259 -1.3532 30.2601
OCI-Ly3 CTRP2 4.4028 6.6651 4.0519 12.2045
HD-MY-Z CTRP2 4.4031 7.3573 3.7796 13.2495
RL CTRP2 4.5114 6.7719 4.1287 11.6058
Granta-519 CTRP2 4.718 8.016 3.8138 12.2945
MHH-CALL-3 CTRP2 4.743 10.6308 2.5932 17.1237
K-562 CTRP2 4.8451 7.5539 4.151 10.6231
L-428 CTRP2 4.9335 7.3296 4.3407 9.6408
ME1 CTRP2 4.9886 8.8305 3.6968 12.1101
GDM-1 CTRP2 5.4511 8.5519 4.2674 8.6991
OCI-Ly10 CTRP2 5.7286 8.1163 4.7348 6.1462
JVM-3 CTRP2 5.7891 10.7912 3.455 11.364
KHM-1B CTRP2 5.8662 6.7399 5.5389 2.4956
P3HR-1 CTRP2 6.7203 12.5877 3.3176 10.1717
Toledo CTRP2 7.1296 20.1426 -0.122 21.3768
Reh CTRP2 7.7499 9.984 5.2488 1.1605
Raji CTRP2 7.7669 9.3745 5.5033 0.4422
Karpas-620 CTRP2 7.7839 9.0168 5.643 0.1647
KMM-1 CTRP2 8.527 10.7426 5.3033 0.5497
REC-1 CTRP2 9.0578 11.0326 5.4058 0.2059
⏷ Show the Full List of 145 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 2.9368 4.8807 2.8855 20.8767
TE15 CTRP2 3.4172 7.8363 2.5466 20.686
TE-6 CTRP2 1.2518 7.1041 0.2049 30.7656
TE-11 CTRP2 3.0993 5.0103 3.0423 19.8137
OE21 CTRP2 3.1514 5.3868 3.0394 19.6568
KYSE-180 CTRP2 3.286 4.8307 3.2587 18.4687
TE-4 CTRP2 3.3655 14.2811 -0.475 30.3972
TE-9 CTRP2 3.4884 5.3514 3.4091 17.2988
TE-5 CTRP2 3.6792 6.6813 3.265 17.2403
KYSE-70 CTRP2 3.8589 6.9988 3.3445 16.4258
KYSE-410 CTRP2 3.8718 10.1829 1.9703 21.62
TE-14 CTRP2 4.0737 6.9068 3.6091 14.8149
KYSE-140 CTRP2 4.1938 6.8596 3.7555 13.9198
TE-10 CTRP2 4.2183 6.818 3.7973 13.692
KYSE-150 CTRP2 4.4853 9.2873 2.9925 16.1618
KYSE-30 CTRP2 5.039 9.9273 3.2124 13.9705
COLO 680N CTRP2 5.0796 8.7734 3.8111 11.4291
EC-GI-10 CTRP2 5.1645 7.3815 4.5513 8.2101
TE-1 CTRP2 5.7654 9.5227 4.0676 8.8617
OE33 CTRP2 5.8844 9.6316 4.1157 8.4192
KYSE-510 CTRP2 6.469 13.0417 2.8929 12.3356
KYSE-520 CTRP2 6.8213 11.9983 3.6875 8.4855
KYSE-450 CTRP2 6.9614 9.7624 4.8829 3.3699
OE19 CTRP2 7.0874 9.6341 5.0265 2.6347
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 4.5247 8.8905 3.2174 15.1678
Hs 766T CTRP2 2.5368 10.8529 0.3297 30.5981
SU.86.86 CTRP2 2.68 13.2442 -0.6368 32.6083
Panc 08.13 CTRP2 2.7527 5.0993 2.659 22.2487
BxPC-3 CTRP2 3.1967 5.2069 3.1187 19.2371
PaTu 8988s CTRP2 3.2485 9.4005 1.7028 24.2409
KP-4 CTRP2 3.5949 6.9071 3.0943 18.1217
TCC-Pan2 CTRP2 3.7993 7.9657 2.8938 18.3151
MIA PaCa-2 CTRP2 3.8276 5.9803 3.6423 15.4148
HPAC CTRP2 3.9519 6.1042 3.7442 14.669
PK-59 CTRP2 3.9523 6.4467 3.6399 15.05
KP-3 CTRP2 4.0882 8.3742 3.0149 17.0776
QGP-1 CTRP2 4.095 7.6829 3.3213 15.8633
SNU-213 CTRP2 4.257 10.4275 2.2297 19.6861
Capan-1 CTRP2 4.2971 7.7901 3.4853 14.6838
HuP-T4 CTRP2 4.4748 6.4035 4.2215 11.361
Panc 05.04 CTRP2 4.4797 5.6198 4.4311 10.5899
L3.3 CTRP2 4.5285 5.3183 4.5181 10.1338
YAPC CTRP2 4.5659 6.4381 4.3085 10.7717
Capan-2 CTRP2 4.5923 7.7461 3.8079 12.6388
PSN1 CTRP2 4.6966 7.5647 3.9946 11.6282
Panc 03.27 CTRP2 4.7518 7.1954 4.2114 10.6281
SW1990 CTRP2 4.9915 8.7918 3.7181 12.0163
KP-2 CTRP2 5.079 8.1565 4.1055 10.2265
Panc 10.05 CTRP2 5.0913 8.6415 3.8858 11.0958
PK-45H CTRP2 5.1655 11.2351 2.6846 15.8056
HuP-T3 CTRP2 5.3441 7.3176 4.7595 6.9242
SNU-410 CTRP2 5.347 20.1414 -1.5934 28.4187
DAN-G CTRP2 5.4361 6.2573 5.3123 4.4987
Panc 04.03 CTRP2 5.6427 7.8684 4.7792 6.1477
AsPC-1 CTRP2 5.6643 9.0736 4.2024 8.5081
PaTu 8988t CTRP2 5.8948 9.4784 4.2012 8.0398
Panc 02.03 CTRP2 6.1052 8.1817 5.026 4.165
CFPAC-1 CTRP2 6.7487 9.259 4.9795 3.2857
PaTu 8902 CTRP2 6.9128 9.916 4.7759 3.8707
SUIT-2 CTRP2 6.9456 10.669 4.4333 5.2171
HPAF-II CTRP2 8.2222 13.587 3.8968 5.5732
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 5.0063 7.303 4.4269 9.1102
Hs 852.T CTRP2 2.6636 8.3308 1.5512 26.4371
LOX-IMVI CTRP2 2.8918 5.158 2.799 21.319
G-361 CTRP2 3.3153 4.8088 3.2912 18.2624
WM983B CTRP2 3.4054 7.5109 2.6639 20.2783
WM88 CTRP2 3.7606 6.8288 3.3011 16.87
A-375 CTRP2 3.7899 5.7831 3.6501 15.5035
RPMI-7951 CTRP2 3.8431 5.5481 3.7571 14.9599
CJM [Human melanoma] CTRP2 3.9953 6.2718 3.7422 14.5459
Mel JuSo CTRP2 4.0211 7.3583 3.3773 15.8477
HMCB CTRP2 4.4723 7.3088 3.8723 12.7021
IPC-298 CTRP2 4.5113 7.6797 3.7541 13.0624
WM266-4 CTRP2 4.6182 7.5456 3.9225 12.1179
Hs 944.T CTRP2 4.6357 9.4151 3.0779 15.4558
WT2-iPS CTRP2 4.6362 6.6008 4.3264 10.5025
Mel Ho CTRP2 4.7125 6.4217 4.4728 9.733
WM1799 CTRP2 4.7209 6.5287 4.4438 9.8177
WM793 CTRP2 4.7233 6.7716 4.3548 10.1494
IGR-37 CTRP2 4.726 6.8232 4.3374 10.2087
Hs 936.T CTRP2 4.7471 7.2305 4.1916 10.7183
SK-MEL-1 CTRP2 4.7639 6.6306 4.4523 9.6637
UACC-62 CTRP2 4.7871 6.742 4.4343 9.6673
UACC-257 CTRP2 4.8591 8.6284 3.6682 12.5352
COLO 792 CTRP2 4.8785 8.4441 3.7741 12.0584
MeWo CTRP2 4.8983 7.2742 4.329 9.7787
IGR-1 CTRP2 4.9801 6.9528 4.5518 8.6859
HT-144 CTRP2 4.9805 7.0472 4.5122 8.84
SK-MEL-30 CTRP2 4.9865 8.5063 3.8497 11.4911
MDA-MB-435S CTRP2 5.1047 9.6867 3.391 13.0938
RVH-421 CTRP2 5.1213 8.229 4.1121 10.0986
COLO 800 CTRP2 5.1803 7.1395 4.6768 7.6675
Hs 294T CTRP2 5.1915 8.2253 4.1814 9.6487
SK-MEL-3 CTRP2 5.2524 7.4043 4.6284 7.6805
WM115 CTRP2 5.2732 6.2375 5.1431 5.6034
SK-MEL-5 CTRP2 5.2868 6.229 5.1607 5.4978
SK-MEL-24 CTRP2 5.5359 8.7039 4.2703 8.4999
COLO 829 CTRP2 5.638 6.3049 5.5101 3.1781
SK-MEL-2 CTRP2 5.8677 6.7268 5.5467 2.4603
Hs 895.T CTRP2 6.0355 14.8655 1.6265 17.9542
IGR-39 CTRP2 6.1573 9.34 4.4898 6.3196
A2058 CTRP2 6.2268 8.3648 5.0325 3.9139
SK-MEL-31 CTRP2 6.8546 10.6205 4.3914 5.5308
SK-MEL-28 CTRP2 6.9202 11.7814 3.869 7.5751
Hs 940.T CTRP2 6.9317 13.1936 3.1797 10.3622
K029AX CTRP2 7.1471 10.8881 4.4685 4.773
A101D CTRP2 7.262 9.8328 5.0431 2.3577
Hs 688(A).T CTRP2 7.8831 18.3926 1.3276 15.6208
Hs 934.T CTRP2 8.6371 41.0831 -9.3639 33.8502
Hs 839.T CTRP2 9.4233 18.5944 2.3126 9.9
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MHH-NB-11 CTRP2 1.3437 3.8545 1.307 31.439
CHP-212 CTRP2 1.6725 3.3766 1.667 29.1443
Kelly CTRP2 2.6524 3.2311 2.6524 22.598
KP-N-SI9s CTRP2 2.691 6.4856 2.2554 23.8698
NB1 CTRP2 2.7702 4.3749 2.7539 21.8676
NH-6 CTRP2 3.0623 7.1404 2.4364 22.1081
CHP-126 CTRP2 3.0995 5.6635 2.9259 20.2188
SK-N-FI CTRP2 3.1506 6.1692 2.8514 20.3284
SK-N-SH CTRP2 3.5799 6.346 3.2668 17.5262
SK-N-DZ CTRP2 3.9869 6.6162 3.6204 15.0213
SK-N-BE(2) CTRP2 4.355 8.3915 3.2779 15.3527
SK-N-AS CTRP2 4.4366 7.6205 3.7027 13.4614
KP-N-YN CTRP2 8.0978 9.9184 5.436 0.4447
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 3.3237 5.0627 3.2743 18.2928
SNU-478 CTRP2 3.4107 6.5228 3.0266 18.9103
HuH-28 CTRP2 4.2734 9.9029 2.495 18.6338
HuCC-T1 CTRP2 4.882 6.7194 4.544 8.9828
SNU-308 CTRP2 4.925 8.5652 3.7621 11.995
SNU-1196 CTRP2 5.4535 8.6437 4.2246 8.8712
SNU-869 CTRP2 6.0929 8.5507 4.8314 5.0056
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TC71 CTRP2 1.6452 2.8185 1.6449 29.309
SK-ES-1 CTRP2 2.0708 4.4443 2.0176 26.6519
SK-N-MC CTRP2 2.4705 3.2964 2.4704 23.8102
A-673 CTRP2 2.596 4.5569 2.5593 23.0973
G-292 clone A141B1 CTRP2 2.6667 4.5041 2.6378 22.5998
MHH-ES-1 CTRP2 2.7606 5.3028 2.6325 22.3154
CAL-78 CTRP2 2.9359 7.2243 2.2698 23.0873
CADO-ES1 CTRP2 3.0137 4.1629 3.0106 20.2013
SaOS-2 CTRP2 3.1059 5.6852 2.928 20.1913
SJSA-1 CTRP2 3.3395 8.3381 2.2575 21.9815
HOS CTRP2 4.9592 7.7479 4.178 10.226
SW1353 CTRP2 5.4206 13.3998 1.8348 18.4803
MG-63 CTRP2 7.1314 16.6832 1.6015 15.9745
Hs 888.T CTRP2 7.3412 17.6934 1.2622 16.7631
Hs 822.T CTRP2 7.7786 15.6631 2.5926 11.2612
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 72 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 CTRP2 2.2486 3.6501 2.2453 25.2993
MDA-MB-157 CTRP2 2.8727 5.2434 2.7642 21.5006
HMC-1-8 CTRP2 2.9056 4.3886 2.8928 20.9537
AU565 CTRP2 2.9581 5.2246 2.8595 20.8976
CAL-51 CTRP2 3.0133 6.8838 2.4744 22.1122
SK-BR-3 CTRP2 3.5091 5.9342 3.3069 17.5948
MDA-MB-453 CTRP2 3.8673 7.4356 3.1837 17.0149
CAL-148 CTRP2 3.9071 6.6221 3.532 15.5829
ZR-75-1 CTRP2 3.9165 6.537 3.5712 15.4094
MDA-MB-468 CTRP2 4.6037 6.1503 4.442 10.1677
CAL-85-1 CTRP2 4.6433 6.8189 4.2512 10.7691
BT-549 CTRP2 4.8133 10.5378 2.7042 16.5245
HDQ-P1 CTRP2 4.8605 8.279 3.834 11.8593
BT-20 CTRP2 4.9321 6.1539 4.799 7.8801
HCC38 CTRP2 4.9897 9.8972 3.1813 14.2092
HCC2218 CTRP2 5.1523 7.6851 4.3989 8.8558
EFM-192A CTRP2 5.2138 7.1165 4.7211 7.405
MDA-MB-231 CTRP2 5.2308 10.241 3.2347 13.4505
HCC1500 CTRP2 5.5819 6.6763 5.2919 4.1858
MDA-MB-415 CTRP2 5.695 7.1992 5.155 4.4723
MDA-MB-361 CTRP2 5.7579 20.8872 -1.6171 27.6505
HCC202 CTRP2 5.9274 9.5731 4.1816 8.0574
HCC1395 CTRP2 5.9914 10.6529 3.6959 9.9622
HCC1419 CTRP2 6.0381 9.3353 4.3936 6.9505
BT-474 CTRP2 6.1413 9.177 4.5581 6.0625
CAL-120 CTRP2 6.1705 7.9581 5.1905 3.353
MCF-7 CTRP2 6.3315 11.5086 3.5477 9.9298
ZR-75-30 CTRP2 6.3811 9.4239 4.6264 5.3411
HCC1428 CTRP2 6.3946 9.6975 4.5009 5.8422
HCC1937 CTRP2 6.7192 9.3867 4.8968 3.6668
JIMT-1 CTRP2 6.7306 10.8679 4.1779 6.6138
CAMA-1 CTRP2 7.0384 13.7947 2.9632 11.0428
T-47D CTRP2 7.0919 15.1669 2.324 13.4216
KPL-1 CTRP2 7.1111 15.563 2.1423 14.0659
HCC1143 CTRP2 7.5509 11.5256 4.4346 4.3498
Hs 578Bst CTRP2 7.6825 11.3405 4.6051 3.5222
HCC1954 CTRP2 7.8474 10.4539 5.099 1.5633
HCC1806 CTRP2 8.3653 15.5498 3.0591 8.6042
BT 416 CTRP2 1.8941 5.0412 1.7442 28.1575
BT 239 CTRP2 1.9548 4.9944 1.8179 27.7091
BT 440 CTRP2 2.7792 6.7347 2.2712 23.5468
BT 145 CTRP2 3.4762 6.3061 3.166 18.2044
BT164 CTRP2 3.5327 5.5675 3.4173 17.1296
BT 286 CTRP2 3.7491 7.3802 3.0804 17.7379
BT 482 CTRP2 3.9945 6.6877 3.6036 15.0621
BT 271 CTRP2 4.0647 8.5276 2.9227 17.4988
BT 228 CTRP2 4.1132 7.1606 3.5537 14.9154
BT 504 CTRP2 4.1492 7.2286 3.5649 14.773
BT 172 CTRP2 4.1866 7.8754 3.3344 15.5677
BT 231 CTRP2 4.2572 6.98 3.7774 13.6582
BT 245 CTRP2 4.4473 7.175 3.9013 12.6569
BT147 CTRP2 4.67 8.8207 3.3928 14.1074
BT 139 CTRP2 4.7658 6.5332 4.4905 9.5134
BT 330 CTRP2 4.9799 8.2217 3.978 10.9842
BT 248 CTRP2 5.0588 9.5458 3.4171 13.0911
BT 112 CTRP2 5.213 9.1318 3.7629 11.3209
BT 428 CTRP2 5.3124 7.2445 4.762 6.9926
BT 333 CTRP2 5.3246 7.9717 4.4305 8.3137
BT 131 CTRP2 5.3889 7.138 4.8873 6.2971
BT 159 CTRP2 5.5033 8.3375 4.4207 7.9466
BT 328 CTRP2 5.6555 9.5293 3.9681 9.5052
BT 498 CTRP2 5.7583 6.5682 5.5178 2.8355
BT 232 CTRP2 5.872 9.8149 4.0137 8.8714
BT 187 CTRP2 5.8976 9.1278 4.3787 7.2894
BT 179 CTRP2 6.0422 10.4951 3.8173 9.3574
BT 359 CTRP2 6.1633 9.1732 4.5779 5.9382
BT 340 CTRP2 6.1681 8.5277 4.9043 4.559
BT 444 CTRP2 6.2404 9.6109 4.4217 6.4511
BT 422 CTRP2 6.2683 7.4793 5.5039 1.8746
BT 216 CTRP2 6.2845 9.8466 4.3394 6.7155
BT 320 CTRP2 7.198 13.0815 3.4348 8.8908
BT 224 CTRP2 7.9934 12.5604 4.2321 4.5713
⏷ Show the Full List of 72 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 3.982 5.4575 3.9224 13.9428
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KNS-60 CTRP2 2.2824 6.3492 1.8517 26.5526
D283 Med CTRP2 2.368 4.018 2.3568 24.5302
SF268 CTRP2 2.6824 8.19 1.6278 26.1186
SF539 CTRP2 2.9387 6.9852 2.3584 22.7559
42-MG-BA CTRP2 3.7073 10.1273 1.8337 22.5421
LN-18 CTRP2 3.9668 5.9069 3.813 14.3758
SNU-466 CTRP2 4.1943 5.5815 4.1302 12.5445
SNU-489 CTRP2 4.3407 6.0676 4.1787 11.9177
M059K CTRP2 4.4731 7.8238 3.6516 13.5671
SF126 CTRP2 4.5122 10.0932 2.6348 17.5077
ONS-76 CTRP2 4.5504 7.6801 3.7941 12.8024
SNU-738 CTRP2 4.6639 7.4684 4.0032 11.6795
YH-13 CTRP2 4.7714 7.482 4.1077 10.9853
GB-1 CTRP2 4.7784 9.867 2.9973 15.4402
AM-38 CTRP2 4.8043 6.9664 4.3622 9.8981
CAS-1 CTRP2 4.8237 10.1873 2.8846 15.785
SNB-75 CTRP2 5.0128 11.2384 2.5445 16.6962
SF295 CTRP2 5.3689 7.4083 4.7414 6.9372
Daoy CTRP2 5.5013 10.0754 3.5602 11.5265
DK-MG CTRP2 5.5911 10.6037 3.3768 12.0937
Hs 683 CTRP2 5.6176 7.7919 4.7937 6.1434
8-MG-BA CTRP2 5.6932 9.3179 4.1065 8.8483
CCF-STTG1 CTRP2 5.9122 11.9818 2.9648 13.1177
SW1088 CTRP2 5.9406 11.0849 3.4371 11.1344
SNU-201 CTRP2 5.952 10.5589 3.7097 9.9819
TM-31 CTRP2 6.0005 9.9124 4.0737 8.3658
Becker CTRP2 6.0875 10.7269 3.7389 9.5965
U-118MG CTRP2 6.0985 7.6439 5.2893 3.0712
SNU-626 CTRP2 6.1451 8.1791 5.0598 3.9484
GaMG CTRP2 6.1581 11.7725 3.2746 11.3791
YKG-1 CTRP2 6.1884 10.6968 3.8371 8.9953
KALS-1 CTRP2 6.2225 13.0326 2.6975 13.575
GOS-3 CTRP2 6.239 11.2115 3.6212 9.7981
SW1783 CTRP2 6.2849 11.2472 3.6406 9.6318
LN-229 CTRP2 6.3405 13.1896 2.7155 13.279
DBTRG-05MG CTRP2 6.445 14.3388 2.2261 14.9672
GMS-10 CTRP2 6.5416 11.9816 3.4793 9.8287
SNU-1105 CTRP2 6.6243 7.9336 5.5283 1.2723
KNS-42 CTRP2 6.6245 9.5596 4.7437 4.4444
A-172 CTRP2 6.8241 13.3297 3.0294 11.1508
U-251MG CTRP2 7.2525 17.325 1.3766 16.5337
U-87MG ATCC CTRP2 7.3982 9.0489 5.4641 0.7643
KG-1-C CTRP2 7.9336 16.759 2.1684 12.5929
NMC-G1 CTRP2 7.9556 10.3673 5.1913 1.1812
T98G CTRP2 8.0089 15.1299 3.0164 9.2845
KNS-81 CTRP2 10.4883 28.762 -1.8576 20.4569
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2 0.1681 3.9715 0.0557 39.4706
JHUEM-7 CTRP2 1.9814 5.0496 1.8369 27.5585
AN3-CA CTRP2 2.2414 4.6702 2.1727 25.5684
HEC-151 CTRP2 3.2101 4.5439 3.1988 18.9206
RL95-2 CTRP2 3.2108 7.583 2.4286 21.7086
MFE-296 CTRP2 3.6572 8.7509 2.4078 20.5533
HEC-265 CTRP2 3.6999 5.7237 3.5656 16.0829
JHUEM-1 CTRP2 3.7482 5.4707 3.6686 15.5695
HEC-1-A CTRP2 4.2615 8.9536 2.9273 16.9763
HEC-6 CTRP2 4.4893 6.4828 4.2101 11.3617
ESS-1 CTRP2 4.7692 7.2086 4.2239 10.5329
HEC-251 CTRP2 4.8127 7.9158 3.9545 11.4919
HEC-59 CTRP2 4.8402 6.616 4.5394 9.1171
HEC-108 CTRP2 4.9142 7.212 4.3725 9.565
EN CTRP2 4.9595 5.971 4.8796 7.5054
KLE CTRP2 5.0279 7.1823 4.5023 8.7544
MFE-319 CTRP2 5.4791 6.5232 5.2532 4.6072
HEC-50B CTRP2 5.5153 10.5989 3.3124 12.5178
EFE-184 CTRP2 6.802 12.5219 3.4133 9.64
HEC-1-B CTRP2 7.2819 14.0356 3.0274 10.3804
Ishikawa (Heraklio) 02 ER- CTRP2 8.7948 25.7953 -1.643 22.4311
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-54 CTRP2 3.6181 6.2171 3.3474 17.1175
UO-31 CTRP2 3.9523 8.9073 2.6382 18.8953
TUHR4TKB CTRP2 4.0545 6.2236 3.8212 14.0798
TUHR10TKB CTRP2 4.13 6.0213 3.9614 13.3428
KMRC-2 CTRP2 4.4276 7.9558 3.5468 14.0999
VMRC-RCW CTRP2 4.6918 6.8352 4.2964 10.461
SNU-1272 CTRP2 4.7536 8.5979 3.5795 13.1503
BFTC-909 CTRP2 4.8976 7.736 4.1218 10.6065
786-O CTRP2 4.9452 7.7045 4.1839 10.2374
KMRC-1 CTRP2 5.2163 6.2171 5.0883 5.9732
VMRC-RCZ CTRP2 5.4756 8.4189 4.3552 8.28
RCC10RGB CTRP2 6.0791 8.4693 4.8607 4.909
OS-RC-2 CTRP2 6.1205 14.1234 2.0682 16.1846
KMRC-20 CTRP2 6.4252 10.1003 4.3244 6.5264
A-498 CTRP2 6.4737 9.2884 4.7648 4.6047
ACHN CTRP2 7.2719 11.0636 4.4694 4.5915
Caki-2 CTRP2 7.6082 11.0184 4.7083 3.2179
769-P CTRP2 7.811 13.6695 3.5848 7.3524
Caki-1 CTRP2 9.4224 17.6831 2.7417 8.3682
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H716 CTRP2 -0.0996 2.6469 -0.1178 40.9861
SW48 CTRP2 0.6124 2.7303 0.6056 36.211
KM12 CTRP2 0.8406 8.2303 -0.3521 37.81
COLO205 CTRP2 2.3883 4.0244 2.3774 24.3938
SW948 CTRP2 2.4629 4.8009 2.3918 24.1011
SW620 CTRP2 2.6555 5.7469 2.4228 23.3822
GP2d CTRP2 2.7097 7.1218 2.0629 24.5036
SNU-81 CTRP2 2.8034 6.3472 2.4203 22.9367
LS513 CTRP2 2.8145 4.0111 2.8117 21.5274
SNU-C1 CTRP2 2.9094 4.9533 2.8475 21.0954
COLO201 CTRP2 3.0884 4.977 3.0349 19.8742
CCK-81 CTRP2 3.1595 5.5247 3.0212 19.6951
COLO 320 CTRP2 3.1688 5.8997 2.9445 19.9383
HT115 CTRP2 3.4615 6.4705 3.0987 18.4951
CL-11 CTRP2 3.5671 10.4567 1.5419 23.9408
NCI-H747 CTRP2 3.5684 9.0808 2.1709 21.6778
SK-CO-1 CTRP2 3.661 5.5184 3.5657 16.205
LoVo CTRP2 3.7746 6.1715 3.5314 15.9766
MDST8 CTRP2 3.8351 4.7032 3.8321 14.7287
SNU-407 CTRP2 3.8443 6.0461 3.6429 15.3618
NCI-H508 CTRP2 3.8731 6.2376 3.6193 15.3606
OUMS-23 CTRP2 4.01 4.7808 4.0078 13.5608
HT-55 CTRP2 4.0293 6.2692 3.78 14.3058
SNU-C5 CTRP2 4.0302 6.2587 3.7842 14.2877
LS180 CTRP2 4.1824 7.1564 3.6287 14.436
HCT 116 CTRP2 4.4118 17.8523 -1.2698 29.7118
LS123 CTRP2 4.4538 6.1215 4.2869 11.1834
SNU-61 CTRP2 4.4815 6.332 4.2524 11.2271
T84 CTRP2 4.637 6.704 4.2887 10.6433
LS411N CTRP2 4.6456 7.0015 4.1808 11.0336
COLO 678 CTRP2 4.6569 8.9191 3.3337 14.3772
SNU-503 CTRP2 4.7307 8.5619 3.5738 13.229
SW1417 CTRP2 4.9029 7.9807 4.0146 11.0246
HCT 15 CTRP2 4.9058 6.5724 4.6262 8.6025
LS1034 CTRP2 4.9653 7.377 4.3521 9.5135
RKO CTRP2 5.0514 12.7262 1.8437 19.2549
C2BBe1 CTRP2 5.0989 9.6491 3.4041 13.0534
HCC-56 CTRP2 5.4759 6.9331 5.0683 5.3506
HCT 8 CTRP2 5.4768 14.5542 1.3077 20.2113
DLD-1 CTRP2 5.4836 7.8829 4.6243 7.1476
SNU-C4 CTRP2 5.5468 6.1166 5.48 3.5519
RCM-1 [Human ESC] CTRP2 6.8757 10.6243 4.4048 5.4423
SNU-C2A CTRP2 7.1 10.6412 4.5551 4.4916
CW-2 CTRP2 7.3653 10.8922 4.6132 3.8927
HT-29 CTRP2 12.4308 36.2347 -4.1164 22.4668
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-886 CTRP2 2.5708 5.6899 2.3442 27.6294
SNU-761 CTRP2 2.6077 19.2388 -4.1733 36.2421
Li-7 CTRP2 3.1488 6.3467 2.7969 20.5311
Hep 3B2.1-7 CTRP2 3.3916 9.92 1.614 24.1607
SNU-182 CTRP2 3.6587 5.7274 3.52 16.373
JHH-5 CTRP2 3.8242 6.7962 3.3813 16.3861
HuH-6 CTRP2 4.0058 6.4516 3.6964 14.6833
Hep-G2 CTRP2 4.4695 8.5159 3.3362 14.8311
SNU-398 CTRP2 4.494 11.4303 1.9709 20.0762
JHH-1 CTRP2 4.6778 6.1216 4.5313 9.6196
SNU-423 CTRP2 4.8363 8.4339 3.7376 12.3086
SNU-475 CTRP2 5.2647 8.6842 4.0293 10.1046
SK-HEP-1 CTRP2 5.4364 6.1856 5.3375 4.4038
JHH-4 CTRP2 5.4559 8.6992 4.1995 8.9705
HuH-1 CTRP2 5.4891 8.6664 4.246 8.7037
HLF CTRP2 5.6181 8.3177 4.5355 7.216
SNU-449 CTRP2 5.6539 7.6597 4.892 5.6545
PLC/PRF/5 CTRP2 5.9268 7.2811 5.3254 3.257
SNU-387 CTRP2 6.0066 13.4752 2.2975 15.5477
JHH-2 CTRP2 6.2403 12.8475 2.8047 13.1172
JHH-6 CTRP2 6.4242 7.7768 5.4707 1.7696
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 140 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2444 CTRP2 0.6476 35.3285 -13.9016 45.944
VMRC-LCD CTRP2 1.8079 4.4641 1.7373 28.4614
DV-90 CTRP2 1.9014 3.8346 1.8856 27.6541
COR-L47 CTRP2 2.0138 7.8775 1.0375 30.1122
NCI-H810 CTRP2 2.198 5.3795 2.0078 26.2754
NCI-H1341 CTRP2 2.2918 3.7149 2.2879 25.0134
NCI-H1581 CTRP2 2.3168 6.3901 1.8769 26.3576
COR-L279 CTRP2 2.32 4.7183 2.2503 25.0478
NCI-H211 CTRP2 2.3716 4.2915 2.3459 24.5549
HCC44 CTRP2 2.4289 5.595 2.2117 24.8339
HOP-62 CTRP2 2.4504 12.6977 -0.6051 33.1827
NCI-H524 CTRP2 2.4639 6.979 1.8469 26.0102
NCI-H1975 CTRP2 2.5247 4.0202 2.517 23.4743
HCC15 CTRP2 2.5891 5.8031 2.3366 23.8936
EPLC-272H CTRP2 2.6851 5.6282 2.483 23.0771
HCC95 CTRP2 2.7728 5.107 2.6794 22.1135
Lu-99 CTRP2 2.786 4.9419 2.7176 21.9398
HCC1588 CTRP2 2.86 4.5721 2.8342 21.3015
NCI-H1694 CTRP2 2.8633 4.0842 2.8597 21.205
DMS 53 CTRP2 2.943 6.8133 2.4225 22.5099
NCI-H1563 CTRP2 2.9526 5.9143 2.7049 21.4597
NCI-H2087 CTRP2 3.01 10.9612 0.7552 28.0127
NCI-H2081 CTRP2 3.0543 6.1429 2.7538 20.9731
HARA [Human squamous cell lung carcinoma] CTRP2 3.0624 6.0919 2.777 20.8646
LXF 289 CTRP2 3.078 5.2745 2.9801 20.0968
NCI-H1734 CTRP2 3.084 6.0531 2.8113 20.6756
HCC827 CTRP2 3.1482 6.2477 2.826 20.4275
DMS 114 CTRP2 3.1547 5.3086 3.0569 19.5852
MOR/CPR CTRP2 3.1841 4.3216 3.18 19.0694
NCI-H2405 CTRP2 3.185 8.0301 2.223 22.5416
A-549 CTRP2 3.2616 5.0157 3.2142 18.6996
LUDLU-1 CTRP2 3.2758 5.8042 3.085 19.1064
HCC2108 CTRP2 3.2918 5.8738 3.0852 19.0566
LCLC-97TM1 CTRP2 3.324 6.4847 2.9446 19.4689
NCI-H2009 CTRP2 3.4102 5.2436 3.3421 17.7808
NCI-H1944 CTRP2 3.4349 6.6361 3.0155 18.8804
NCI-H1435 CTRP2 3.4842 4.8893 3.4612 17.1336
SW1271 CTRP2 3.5044 23.3361 -4.7999 37.2598
NCI-H1573 CTRP2 3.5106 6.7766 3.0495 18.5328
NCI-H2122 CTRP2 3.5146 5.1198 3.4702 17.004
NCI-H358 CTRP2 3.5421 7.6372 2.7589 19.5368
NCI-H1184 CTRP2 3.5765 6.8274 3.103 18.1423
RERF-LC-A1 CTRP2 3.5806 7.0493 3.027 18.4154
COLO 668 CTRP2 3.6092 7.2563 2.9797 18.5127
NCI-H2110 CTRP2 3.6261 6.0425 3.4058 16.8816
NCI-H2106 CTRP2 3.6278 7.0788 3.0668 18.1309
HCC1438 CTRP2 3.6646 8.5184 2.5172 20.1188
NCI-H2030 CTRP2 3.6704 5.266 3.6171 15.9966
NCI-H1623 CTRP2 3.694 7.2162 3.0857 17.8722
NCI-H1155 CTRP2 3.7058 6.2951 3.4196 16.5912
NCI-H1838 CTRP2 3.7409 6.696 3.3266 16.8314
NCI-H446 CTRP2 3.7413 6.4524 3.4088 16.5251
NCI-H1703 CTRP2 3.7541 6.0043 3.5558 15.9507
EBC-1 CTRP2 3.7783 6.3246 3.4895 16.1186
NCI-H1568 CTRP2 3.7933 5.1411 3.7628 15.0998
HCC1195 CTRP2 3.8253 6.5455 3.4694 16.0542
DMS 454 CTRP2 3.8364 9.2151 2.3818 20.1775
RERF-LC-MS CTRP2 3.8478 6.0775 3.638 15.3688
LK2 CTRP2 3.8975 6.2129 3.6534 15.163
NCI-H838 CTRP2 3.8994 5.7069 3.7863 14.68
Sq-1 CTRP2 3.9041 7.2555 3.2942 16.4899
NCI-H1666 CTRP2 3.9177 8.5214 2.7756 18.4553
NCI-H23 CTRP2 4.0137 5.6021 3.9314 13.8107
NCI-H526 CTRP2 4.0241 5.5444 3.9532 13.7015
NCI-H727 CTRP2 4.0308 6.8731 3.5757 15.0631
NCI-H1339 CTRP2 4.114 6.3125 3.8589 13.7644
NCI-H647 CTRP2 4.1195 7.824 3.2869 15.9317
NCI-H292 CTRP2 4.1597 6.8318 3.7293 14.1159
COR-L95 CTRP2 4.1723 6.8246 3.7455 14.0187
Lu-65 CTRP2 4.1796 7.6616 3.4185 15.2578
SHP-77 CTRP2 4.2269 6.4999 3.9201 13.2059
SK-MES-1 CTRP2 4.2571 6.7727 3.8557 13.3607
NCI-H650 CTRP2 4.2623 7.8774 3.4116 15.065
NCI-H1755 CTRP2 4.2812 6.346 4.0301 12.6386
NCI-H841 CTRP2 4.3093 6.6486 3.9572 12.8289
NCI-H460 CTRP2 4.3659 8.1934 3.3781 14.9275
NCI-H1373 CTRP2 4.4093 6.6015 4.0819 12.0731
NCI-H2023 CTRP2 4.4162 8.0764 3.4815 14.3882
Calu-6 CTRP2 4.4299 6.4655 4.1518 11.7519
LOU-NH91 CTRP2 4.4344 9.0354 3.0607 16.0161
HCC2279 CTRP2 4.4583 5.4153 4.436 10.642
CAL-12T CTRP2 4.4593 13.5678 0.8919 23.8622
NCI-H2029 CTRP2 4.5104 8.3482 3.4539 14.2578
NCI-H1395 CTRP2 4.5265 8.8322 3.2464 15.0477
NCI-H1651 CTRP2 4.5456 8.3472 3.4896 14.0267
NCI-H2126 CTRP2 4.565 7.5595 3.8617 12.4973
NCI-H1105 CTRP2 4.5849 6.0768 4.4427 10.2219
NCI-H1792 CTRP2 4.5876 9.3214 3.0759 15.5798
NCI-H1092 CTRP2 4.5961 6.6083 4.2805 10.7901
NCI-H1299 CTRP2 4.6016 7.604 3.88 12.3292
HCC1833 CTRP2 4.6107 8.9191 3.2884 14.6722
NCI-H520 CTRP2 4.6436 8.3917 3.567 13.4714
DMS 273 CTRP2 4.6452 6.779 4.2687 10.6965
NCI-H1650 CTRP2 4.7225 6.6744 4.3914 10.0119
NCI-H2170 CTRP2 4.7308 7.3785 4.1111 11.0779
NCI-H322 CTRP2 4.7673 6.77 4.4022 9.8452
ChaGo-K-1 CTRP2 4.7825 7.1243 4.2736 10.3025
NCI-H522 CTRP2 4.7933 8.6189 3.6084 12.9367
RERF-LC-Ad2 CTRP2 4.84 9.8542 3.0617 15.0378
SBC-5 CTRP2 4.9571 5.8816 4.8979 7.4478
EKVX CTRP2 4.9588 11.3619 2.4344 17.2455
NCI-H2141 CTRP2 4.9614 6.7021 4.635 8.4134
NCI-H1915 CTRP2 5.0257 7.8134 4.214 9.9157
LCLC-103H CTRP2 5.0439 13.3669 1.5192 20.427
HCC366 CTRP2 5.0694 8.6358 3.8675 11.2219
NCI-H69 CTRP2 5.1723 10.0568 3.272 13.4281
HCC78 CTRP2 5.2113 10.2199 3.2273 13.5237
COR-L105 CTRP2 5.2813 8.787 3.9948 10.2092
NCI-H1869 CTRP2 5.3151 8.1822 4.3201 8.79
NCI-H1355 CTRP2 5.3441 16.5218 0.2113 23.929
SK-LU-1 CTRP2 5.3898 10.3166 3.3409 12.6689
LC-1/sq-SF CTRP2 5.4891 7.1808 4.9662 5.7315
Calu-3 CTRP2 5.5286 7.7025 4.7541 6.5086
NCI-H2196 CTRP2 5.8215 10.1101 3.823 9.7699
KNS-62 CTRP2 5.8475 9.483 4.1584 8.3145
NCI-H2228 CTRP2 5.8727 13.5261 2.1595 16.3386
NCI-H441 CTRP2 5.9566 9.7474 4.1192 8.2613
NCI-H1693 CTRP2 5.9571 15.8626 1.0623 20.0335
NCI-H2085 CTRP2 6.0443 9.428 4.3525 7.1113
DMS 79 CTRP2 6.2122 8.8588 4.7745 5.0226
T3M-10 CTRP2 6.2626 7.9974 5.2432 2.9695
IA-LM CTRP2 6.2749 10.4978 4.0068 8.1254
BEN CTRP2 6.2942 7.7944 5.3679 2.3965
HCC4006 CTRP2 6.4243 8.8643 4.9372 3.9703
Calu-1 CTRP2 6.6047 14.7685 2.14 14.9898
NCI-H661 CTRP2 6.7223 13.9664 2.6331 12.8951
NCI-H196 CTRP2 6.7816 10.6199 4.3382 5.8671
HCC2935 CTRP2 6.783 14.3273 2.5012 13.2955
NCI-H2342 CTRP2 6.8462 15.2853 2.074 14.7908
NCI-H2291 CTRP2 7.0759 11.4915 4.1253 6.2758
COLO 699 CTRP2 7.1086 10.8775 4.447 4.9164
RERF-LC-Ad1 CTRP2 7.2226 8.0661 5.7695 0.1161
NCI-H226 CTRP2 7.2511 21.8998 -0.9015 23.2099
NCI-H889 CTRP2 7.2684 13.2548 3.4014 8.9114
HOP-92 CTRP2 7.3623 28.5865 -4.148 29.472
NCI-H2286 CTRP2 7.9591 10.228 5.2508 1.0009
HCC1171 CTRP2 8.1709 14.9916 3.195 8.3588
NCI-H1793 CTRP2 8.7694 18.7655 1.7868 12.6624
NCI-H2172 CTRP2 9.6682 17.2328 3.1042 6.765
Hs 888.Lu CTRP2 4.8403 10.8338 2.5847 16.9313
⏷ Show the Full List of 140 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 2.7692 4.9263 2.7017 22.0485
H-STS CTRP2 3.3019 5.6547 3.1481 18.8016
P-STS CTRP2 5.225 11.8695 2.4236 16.6949
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 3.1283 5.7084 2.947 20.0544
A2780 CTRP2 1.9477 4.1732 1.9128 27.41
COV434 CTRP2 2.3426 3.9098 2.3347 24.6881
OC 314 CTRP2 2.966 5.3322 2.8491 20.9085
TYK-nu CTRP2 3.2652 5.292 3.1787 18.8102
OVK18 CTRP2 3.5113 5.1667 3.4608 17.0469
IGROV-1 CTRP2 3.5543 9.8107 1.8271 22.9701
MCAS CTRP2 3.597 7.183 2.9947 18.4904
FU-OV-1 CTRP2 3.749 9.2 2.3006 20.7134
HEY A8 CTRP2 3.7575 6.7955 3.3096 16.8467
SNU-119 CTRP2 3.8138 7.5425 3.0841 17.5444
SNU-8 CTRP2 3.9672 5.7305 3.8549 14.2258
COV644 CTRP2 4.2232 5.9184 4.0898 12.5966
OVTOKO CTRP2 4.3333 7.003 3.8495 13.1705
JHOM-1 CTRP2 4.5752 7.7361 3.7948 12.7349
OVCAR-5 CTRP2 4.5887 9.729 2.8827 16.3472
Caov-3 CTRP2 4.8232 8.1913 3.838 11.9347
TOV-112D CTRP2 4.9104 6.799 4.5422 8.9116
EFO-27 CTRP2 4.9362 6.8293 4.5572 8.7833
RMG-I CTRP2 5.1359 9.0807 3.7156 11.6912
SNU-840 CTRP2 5.1861 7.4811 4.5272 8.2535
JHOC-5 CTRP2 5.1988 7.2319 4.6539 7.7123
JHOS-2 CTRP2 5.3376 8.4049 4.2334 9.0956
OAW28 CTRP2 5.3505 10.6633 3.1339 13.5993
OVCAR-4 CTRP2 5.4228 11.8651 2.6011 15.5758
SK-OV-3 CTRP2 5.4754 9.8271 3.6602 11.1681
OAW42 CTRP2 5.5696 8.1982 4.5501 7.2618
TOV-21G CTRP2 5.6403 8.621 4.4056 7.71
ONCO-DG-1 CTRP2 5.6521 8.035 4.7059 6.4323
OV-90 CTRP2 5.8369 8.3534 4.7127 6.0112
OV7 CTRP2 5.9554 8.9527 4.5154 6.6004
Kuramochi CTRP2 6.0283 11.5518 3.2773 11.6191
EFO-21 CTRP2 6.1925 9.7159 4.3306 6.9222
COV362 CTRP2 6.2106 10.0721 4.1673 7.573
OV56 CTRP2 6.234 8.0048 5.2174 3.127
OVCAR-8 CTRP2 6.4219 10.4098 4.1678 7.1865
DOV13 CTRP2 6.7806 12.9758 3.1715 10.6569
OVISE CTRP2 7.3672 11.6511 4.2522 5.3275
OVSAHO CTRP2 7.8482 18.4072 1.2944 15.7898
ES2 CTRP2 9.3778 16.6921 3.1756 6.8497
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 3.865 6.0565 3.6627 15.2274
Yamato-SS CTRP2 4.8009 9.5487 3.1722 14.684
A-204 CTRP2 2.0397 6.5114 1.5381 28.3928
Rh41 CTRP2 2.1712 3.7982 2.1633 25.8304
G-401 CTRP2 2.2405 4.7332 2.1638 25.6012
Tm87-16 CTRP2 2.3723 3.3591 2.372 24.4649
TE 441.T CTRP2 2.4399 3.8338 2.4356 24.0282
TTC-709 CTRP2 2.4991 4.5308 2.4599 23.7511
KYM-1 CTRP2 2.5654 3.7631 2.5636 23.1838
SW982 CTRP2 2.7738 3.5852 2.7737 21.7898
GCT CTRP2 3.3371 7.5798 2.5643 20.8446
TE 617.T CTRP2 3.4133 5.1905 3.3531 17.733
G-402 CTRP2 3.5063 5.3657 3.4259 17.1833
BT-16 CTRP2 3.7552 6.1217 3.5246 16.0603
BT-12 CTRP2 4.4665 6.0687 4.3157 11.0406
Rh18 CTRP2 4.8944 13.1024 1.5165 20.7734
RD CTRP2 4.9671 7.6911 4.212 10.0696
Hs 729.T CTRP2 4.978 8.7113 3.7437 11.9439
HT-1080 CTRP2 5.0894 6.3594 4.9019 7.0375
RKN CTRP2 5.2483 7.4888 4.5852 7.8657
SK-LMS-1 CTRP2 5.8421 9.571 4.1098 8.529
SK-UT-1 CTRP2 6.5321 11.3122 3.8051 8.5007
MES-SA CTRP2 7.3247 8.5164 5.6434 0.3258
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 7.7813 10.8405 4.8925 2.342
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2 3.0784 6.3937 2.7058 21.0742
NCI-H28 CTRP2 3.085 4.8126 3.0493 19.8363
NCI-H2452 CTRP2 3.8934 6.3762 3.5986 15.3759
MPP 89 CTRP2 4.7751 8.0707 3.8458 12.0226
IST-Mes1 CTRP2 4.8312 7.8119 4.0205 11.1801
JL-1 CTRP2 5.0491 9.5075 3.4267 13.0743
ACC-MESO-1 CTRP2 6.1686 9.7052 4.3165 7.0261
NCI-H2052 CTRP2 6.8336 12.5608 3.4182 9.5658
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP CTRP2 2.9067 5.3883 2.7744 21.3573
LNCaP clone FGC CTRP2 4.464 8.235 3.4586 14.357
DU145 CTRP2 5.1092 8.788 3.8322 11.2741
PaCa-3 CTRP2 6.4149 8.0634 5.3245 2.3813
22Rv1 CTRP2 7.2853 12.618 3.7256 7.577
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 2.6011 5.5487 2.4094 23.5995
A-253 CTRP2 7.1703 9.2675 5.2463 1.7045
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 CTRP2 0.6472 2.6727 0.6419 35.9743
KATO III CTRP2 2.0688 8.2214 0.9643 30.1668
SNU-620 CTRP2 2.3979 4.7864 2.3245 24.5421
SNU-1 CTRP2 2.5069 5.262 2.3658 24.0496
ECC10 CTRP2 2.5543 4.6959 2.5014 23.4301
GSS CTRP2 2.5807 4.2411 2.5654 23.1267
23132/87 CTRP2 3.0034 5.7974 2.7897 21.0007
SNU-5 CTRP2 3.0185 4.8186 2.9787 20.2929
NUGC-4 CTRP2 3.2698 7.5203 2.5159 21.2161
HGC-27 CTRP2 3.3404 6.1578 3.0617 18.9924
SNU-719 CTRP2 3.3739 5.6721 3.2225 18.3137
SNU-668 CTRP2 3.869 8.4013 2.7785 18.5725
Fu97 CTRP2 4.0733 9.4931 2.4908 19.1514
GSU CTRP2 4.0877 5.0192 4.0794 13.0637
Hs 746.T CTRP2 4.1274 6.5963 3.7793 14.0201
IM95 CTRP2 4.1681 6.3949 3.8913 13.485
ECC12 CTRP2 4.2415 5.9901 4.0914 12.5347
AGS CTRP2 4.4429 7.8244 3.6205 13.7688
KE-39 CTRP2 4.4599 8.5498 3.311 14.9554
SNU-216 CTRP2 4.4904 7.5288 3.7979 12.9449
HuG1-N CTRP2 4.5019 6.9505 4.0492 11.9363
SH-10-TC CTRP2 4.6408 5.822 4.5671 9.605
NUGC-3 CTRP2 4.6502 5.9853 4.5386 9.6774
MKN74 CTRP2 4.8129 9.9907 2.9699 15.4692
LMSU CTRP2 4.9229 7.5532 4.2301 10.1086
MKN7 CTRP2 5.3808 11.7869 2.6029 15.6586
SNU-601 CTRP2 5.7476 8.9451 4.3399 7.7585
MKN1 CTRP2 7.443 13.9318 3.1968 9.4493
MKN45 CTRP2 9.4414 22.01 0.6848 15.2592
SNG-M CTRP2 3.7032 7.9138 2.8152 18.878
SNU-685 CTRP2 5.3558 9.3806 3.7726 10.9622
SNU-1077 CTRP2 5.9495 9.4435 4.2651 7.6631
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TT CTRP2 2.4434 4.6938 2.3843 24.1901
CGTH-W-1 CTRP2 2.6048 4.9194 2.5273 23.1779
SW579 CTRP2 3.2217 4.9039 3.1843 18.9314
8305C CTRP2 3.3001 5.1951 3.2313 18.5167
ML-1 [Human leukemia] CTRP2 3.5195 11.8564 0.8366 26.382
BHT-101 CTRP2 3.5698 7.1143 2.9912 18.5807
8505C CTRP2 3.8104 9.2393 2.3447 20.3861
B-CPAP CTRP2 3.9938 7.834 3.1521 16.7924
TT2609-C02 CTRP2 4.3145 7.3568 3.6869 13.8496
CAL-62 CTRP2 4.3934 6.6759 4.0379 12.2841
FTC-238 CTRP2 5.0385 7.678 4.2893 9.5799
FTC-133 CTRP2 6.1803 7.7215 5.3162 2.8084
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-10B CTRP2 -0.1569 3.3747 -0.2234 41.4934
SCC-4 CTRP2 2.5017 4.8929 2.4208 23.8762
SCC-25 CTRP2 3.1288 5.0283 3.0714 19.6186
SNU-1214 CTRP2 3.1623 7.917 2.2449 22.5252
CAL-33 CTRP2 3.3094 6.3255 2.9784 19.3887
BICR 18 CTRP2 3.4044 6.4652 3.0383 18.8864
PE/CA-PJ49 CTRP2 3.488 5.8606 3.3025 17.6755
BHY CTRP2 3.5632 5.377 3.4852 16.7962
SNU-899 CTRP2 3.7139 5.9641 3.5226 16.193
PE/CA-PJ34 (clone C12) CTRP2 3.7409 6.136 3.5049 16.1747
BICR 22 CTRP2 3.7666 5.5284 3.6781 15.4778
SNU-1076 CTRP2 3.8313 6.2703 3.5639 15.6881
BICR 31 CTRP2 4.1304 8.1355 3.1634 16.3856
YD-8 CTRP2 4.1897 7.1835 3.6258 14.4271
CAL-27 CTRP2 4.2994 7.6588 3.5441 14.4471
SNU-46 CTRP2 4.5003 7.4844 3.8271 12.804
HSC-2 CTRP2 4.708 8.1489 3.7429 12.6038
SCC-9 CTRP2 4.7891 9.4535 3.2068 14.5723
BICR 16 CTRP2 4.8221 21.8761 -2.9118 31.9886
BICR 56 CTRP2 4.8935 8.0356 3.9799 11.1881
HSC-4 CTRP2 5.1425 10.4265 3.0628 14.3443
BICR 6 CTRP2 5.1993 8.4731 4.0698 10.0885
PE/CA-PJ15 CTRP2 5.3243 7.8789 4.4747 8.1333
FaDu CTRP2 5.4327 9.4346 3.8159 10.6142
SNU-1066 CTRP2 5.4939 8.5285 4.3183 8.3925
SNU-1041 CTRP2 5.4961 11.6778 2.7587 14.7977
PE/CA-PJ41 (clone D2) CTRP2 6.1877 10.535 3.9174 8.6617
HSC-3 CTRP2 6.3222 7.6393 5.465 1.9489
Detroit 562 CTRP2 7.9698 17.2351 1.9613 13.283
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JMSU-1 CTRP2 1.4339 4.5943 1.3217 31.09
RT-112 CTRP2 2.1883 5.7091 1.9228 26.6007
253J CTRP2 2.8256 4.0915 2.8213 21.4582
5637 CTRP2 3.3076 7.7792 2.4539 21.3404
VM-CUB-1 CTRP2 3.9584 7.4307 3.2819 16.3871
KU-19-19 CTRP2 4.1054 7.5149 3.4022 15.521
SCaBER CTRP2 4.1302 6.9691 3.646 14.5153
BFTC-905 CTRP2 4.1415 5.4282 4.0977 12.8261
UM-UC-1 CTRP2 4.4917 7.7781 3.6909 13.3635
UM-UC-3 CTRP2 4.5633 7.1008 4.0537 11.7507
RT-4 CTRP2 4.5666 7.6194 3.8372 12.5895
647V CTRP2 4.661 7.2695 4.0856 11.3629
HT-1197 CTRP2 4.7055 5.395 4.6968 8.9489
SW1710 CTRP2 4.7679 10.3924 2.7325 16.5184
TCCSUP CTRP2 5.1033 10.5188 2.9815 14.7596
T24 CTRP2 5.1565 8.7086 3.9154 10.8223
253J-BV CTRP2 5.2952 7.2299 4.7516 7.0773
HT-1376 CTRP2 5.4899 10.7943 3.1929 13.0607
CAL-29 CTRP2 5.6085 8.3573 4.5072 7.3548
BC-3C CTRP2 5.6879 8.3772 4.5691 6.9255
U-BLC1 CTRP2 5.7206 9.5262 4.0268 9.1248
639V CTRP2 5.9168 9.9381 3.9902 8.8801
J82 CTRP2 6.3276 10.7206 3.938 8.3161
KMBC-2 CTRP2 9.0889 35.1461 -6.0536 29.6784
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 2.5168 4.3379 2.4937 23.5789

References

1 Cellular characterization of a novel focal adhesion kinase inhibitor. J Biol Chem. 2007 May 18;282(20):14845-52.
2 Aryl hydrocarbon receptor-dependent up-regulation of the heterodimeric amino acid transporter LAT1 (SLC7A5)/CD98hc (SLC3A2) by diesel exhaust particle extract in human bronchial epithelial cells. Toxicol Appl Pharmacol. 2016 Jan 1;290:74-85.