Details of the Drug

General Information of Drug (ID: DM3IPSX)

Drug Name
ATLCAR.CD30.CCR4 cells
Indication
Disease Entry ICD 11 Status REF
Immune System disease 4A01-4B41 Phase 1 [1]
Immunoproliferative disorder 2B32 Phase 1 [1]
Lymphatic disease BD9Z Phase 1 [1]
Lymphoma 2A80-2A86 Phase 1 [1]
Neoplasm 2A00-2F9Z Phase 1 [1]
Drug Type
CAR T Cell Therapy
Cross-matching ID
TTD ID
D0U5AQ
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
C-C chemokine receptor type 4 (CCR4) TT7HQD0 CCR4_HUMAN CAR-T-Cell-Therapy(Dual specific) [1]
Lymphocyte activation antigen CD30 (TNFRSF8) TT2GM5R TNR8_HUMAN CAR-T-Cell-Therapy(Dual specific) [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Immune System disease
ICD Disease Classification 4A01-4B41
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
C-C chemokine receptor type 4 (CCR4) DTT CCR4 2.33E-02 3.98E-03 0.03
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT03602157) Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and NHL