Details of the Drug

General Information of Drug (ID: DM471WY)

Drug Name

PTC-725

Synonyms

HCV IRES inhibitors, PTC Therapeutics/Schering-Plough; HCV Internal Ribosome Entry Site inhibitors, PTC Therapeutics/Schering-Plough; HCV replicon RNA replication inhibitors, PTC Therapeutics/Schering-Plough; Hepatitis C virus therapy (oral), PTC Therapeutics/Schering-Plough

Indication

Disease Entry	ICD 11	Status	REF
Hepatitis C virus infection	1E51.1	Investigative	[1]

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C23H18F4N6O2S
Canonical SMILES: CCC1=CC2=C(C=C1F)C(=C(N2C3=NC=CC=N3)C4=NC=C(C=C4)S(=O)(=O)NC(C)C(F)(F)F)C#N
InChI: InChI=1S/C23H18F4N6O2S/c1-3-14-9-20-16(10-18(14)24)17(11-28)21(33(20)22-29-7-4-8-30-22)19-6-5-15(12-31-19)36(34,35)32-13(2)23(25,26)27/h4-10,12-13,32H,3H2,1-2H3/t13-/m0/s1
InChIKey: OBULGMCFXOTNNK-ZDUSSCGKSA-N

Cross-matching ID

PubChem CID: 66731056
ChEBI ID: CHEMBL3120505
TTD ID: D01JPJ

References

1	The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.