Details of the Drug

General Information of Drug (ID: DM4A1KJ)

Drug Name
UNC0638
Synonyms
UNC0638; 1255580-76-7; UNC-0638; UNC 0638; UNII-26A103L2FO; 2-Cyclohexyl-N-(1-isopropylpiperidin-4-yl)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazolin-4-amine; CHEMBL1231795; 26A103L2FO; 2-Cyclohexyl-6-methoxy-N-[1-(1-methylethyl)-4-piperidinyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine; 1255517-77-1; 2-cyclohexyl-6-methoxy-N-[1-(propan-2-yl)piperidin-4-yl]-7-[3-(pyrrolidin-1-yl)propoxy]quinazolin-4-amine; 2-Cyclohexyl-N-(1-isopropyl-4-piperidinyl)-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]-4-quinazolinamine
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 2 Molecular Weight (mw) 509.7
Logarithm of the Partition Coefficient (xlogp) 6.3
Rotatable Bond Count (rotbonds) 10
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C30H47N5O2
IUPAC Name
2-cyclohexyl-6-methoxy-N-(1-propan-2-ylpiperidin-4-yl)-7-(3-pyrrolidin-1-ylpropoxy)quinazolin-4-amine
Canonical SMILES
CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)C5CCCCC5
InChI
InChI=1S/C30H47N5O2/c1-22(2)35-17-12-24(13-18-35)31-30-25-20-27(36-3)28(37-19-9-16-34-14-7-8-15-34)21-26(25)32-29(33-30)23-10-5-4-6-11-23/h20-24H,4-19H2,1-3H3,(H,31,32,33)
InChIKey
QOECJCJVIMVJGX-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
46224516
ChEBI ID
CHEBI:95074
CAS Number
1255580-76-7
TTD ID
D0GK7A

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Euchromatic histone-lysine N-methyltransferase 1 (EHMT1) TTOFXD7 EHMT1_HUMAN Inhibitor [2]
Histone-lysine N-methyltransferase EHMT2 (EHMT2) TTS6RZT EHMT2_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Interferon alpha-2 (IFNA2) OT4GII73 IFNA2_HUMAN Protein Interaction/Cellular Processes [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 3.7504 4.7742 3.7195 12.2426
Hs 888.T CTRP2 0.4935 1.8308 0.4929 30.3207
ES5 GDSC1 1.2641 3.8998 1.1853 45.3172
EW-7 GDSC1; GDSC2 2.1436 3.3831 2.1396 24.5301
Hs 822.T CTRP2 2.3146 2.8978 2.3146 18.1862
EW-18 GDSC1; GDSC2 2.3764 3.8341 2.3609 22.7791
CHSA0108 GDSC1 2.5411 4.7681 2.4184 31.5756
ES1 GDSC1; GDSC2 2.5714 4.2319 2.5327 21.366
MHH-ES-1 GDSC1; GDSC2; CTRP2 2.5758 3.9742 2.559 18.0182
EW-3 GDSC1; GDSC2 2.5949 3.9962 2.5774 21.1017
NOS-1 [Human HNSCC] GDSC1; GDSC2 2.6511 4.027 2.6337 20.6678
EW-1 GDSC1; GDSC2 2.6748 3.8185 2.6684 20.4423
ES7 GDSC1; GDSC2 2.7473 4.6043 2.6706 20.1606
EW-11 GDSC1; GDSC2 2.8478 4.4392 2.8017 19.2635
EW-13 GDSC1; GDSC2 2.8549 5.0593 2.6965 19.6634
ES8 GDSC1; GDSC2 2.9172 4.3889 2.8812 18.6886
ES6 GDSC1; GDSC2 2.9237 4.6425 2.8539 18.7729
EW-16 GDSC1; GDSC2 2.9317 4.7365 2.8467 18.7723
EW-22 GDSC1; GDSC2 3.259 4.3733 3.1475 9.3751
SK-ES-1 GDSC1; GDSC2; CTRP2 3.2597 4.4776 3.2334 13.5765
SJSA-1 GDSC1; GDSC2; CTRP2 3.3972 4.6433 3.3603 12.7128
ES4 GDSC1; GDSC2 3.4046 4.7969 3.346 15.0198
HuO-3N1 GDSC1; GDSC2 3.7056 4.7472 3.6752 12.5861
U2OS GDSC1; GDSC2; CTRP2; CTRP1 3.7547 6.4674 3.2042 12.251
CHSA8926 GDSC1; GDSC2 3.8566 5.2114 3.7515 11.7249
SK-PN-DW GDSC1; GDSC2 3.9128 5.012 3.8563 11.0924
CADO-ES1 GDSC1; GDSC2 4.1205 5.7048 3.8893 10.2295
CAL-78 GDSC1; GDSC2; CTRP2 4.1276 5.7001 3.8987 8.6206
TC-71 GDSC1; GDSC2 4.1536 5.7208 3.9193 9.9887
CHSA0011 GDSC1 4.2187 5.2811 4.1288 12.7805
EW-24 GDSC1; GDSC2 4.2579 5.7837 4.0085 9.2543
SK-N-MC CTRP2 4.3147 6.6189 3.0058 4.4077
SaOS-2 GDSC1; GDSC2; CTRP2 4.3422 5.1431 4.2957 6.5653
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 4.6829 6.8815 3.9616 6.9554
MG-63 GDSC1; GDSC2; CTRP2 4.8179 6.3668 4.3369 5.1334
H-EMC-SS GDSC1; GDSC2 5.0157 6.7816 4.3234 5.5899
SW1353 CTRP2 5.0362 9.5178 2.1166 7.0648
NY GDSC1; GDSC2 5.4107 7.3713 4.3702 4.4368
HuO9 GDSC1; GDSC2 5.9863 9.0698 3.9687 5.2404
A-673 GDSC1; GDSC2; CTRP2 6.7977 13.3211 2.4756 9.1599
HOS GDSC1; GDSC2; CTRP2 7.1908 9.0023 4.7088 0.5318
CAL-72 GDSC1; GDSC2 7.6955 9.1736 4.8458 0.1501
TC71 CTRP2 9.9655 23.2449 -0.3539 13.3036
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 218 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 1.7104 3.0755 1.6839 17.0098
MEC1 CTRP2 2.8667 4.8906 2.4742 10.231
JM1 GDSC1; CTRP2 1.0438 3.4444 1.0011 28.1251
HuT 78 CTRP2 0.5998 9.9437 -1.6649 35.8784
MY-M12 GDSC1 0.8437 4.9832 0.5229 54.6908
DoHH2 CTRP2 0.8685 3.042 0.7949 23.1718
CESS GDSC1; GDSC2 0.8967 3.0211 0.877 34.2072
SU-DHL-5 GDSC1; GDSC2; CTRP1 0.9772 1.8483 0.9772 33.5113
Hs 611.T CTRP2 0.9982 1.9332 0.9976 21.9846
Ki-JK CTRP2 1.0325 3.4216 0.9088 22.191
DND-41 GDSC1; GDSC2 1.0912 2.7714 1.0851 32.6554
Karpas-45 GDSC1; GDSC2 1.1286 1.9966 1.1286 32.3436
NALM-6 GDSC1; GDSC2; CTRP2 1.2153 3.6245 1.1647 27.0294
RPMI-8402 GDSC1; GDSC2; CTRP2 1.2525 3.6485 1.2015 26.7875
ST486 GDSC1 1.274 2.9222 1.2673 45.003
GA-10 GDSC1; GDSC2; CTRP2 1.3858 3.6079 1.2805 20.9281
OCI-Ly19 GDSC1; CTRP2 1.4783 4.0645 1.3917 25.4299
MOLP-8 GDSC1; GDSC2 1.514 3.4295 1.4921 29.4555
Peer CTRP2 1.5821 3.5697 1.4753 18.2189
EoL-1 GDSC1; GDSC2; CTRP2 1.591 2.9543 1.5879 24.4148
HH [Human lymphoma] GDSC1; GDSC2 1.6116 3.7244 1.5718 28.7724
JSC-1 GDSC1; GDSC2 1.6433 2.9938 1.6402 28.3851
MOTN-1 CTRP2 1.645 3.4654 1.618 22.7379
P30/OHK GDSC1; GDSC2 1.6532 3.0858 1.6485 28.3155
MHH-CALL-4 CTRP2 1.6665 2.5245 1.6649 17.2329
LC4-1 GDSC1; GDSC2 1.6684 3.9408 1.6097 28.4086
TALL-1 [Human adult T-ALL] CTRP2 1.6694 3.233 1.6233 17.373
ALL-SIL GDSC1; GDSC2; CTRP2 1.6772 3.1666 1.671 23.8614
KMS-21-BM CTRP2 1.7331 4.1302 1.5062 17.6022
KO52 CTRP2 1.7435 3.3698 1.6836 16.8963
CCRF-CEM GDSC1; GDSC2 1.7864 3.0451 1.784 27.2788
DB GDSC1; GDSC2; CTRP2 1.7887 3.7846 1.7523 23.2319
NCO2 CTRP2 1.7894 3.6783 1.6782 16.7608
SUP-T11 CTRP2 1.8063 3.136 1.779 16.3303
OCI-Ly10 CTRP2; CTRP1 1.8132 4.8397 1.5741 22.4307
PF-382 GDSC1; GDSC2; CTRP2 1.8278 3.4312 1.8157 22.8955
DEL GDSC1; GDSC2; CTRP2 1.8525 3.2025 1.8481 22.7087
BE-13 GDSC1; GDSC2 1.8912 3.2279 1.8869 26.4782
ALL-PO GDSC1; GDSC2 1.9162 3.7665 1.8872 26.381
697 GDSC1; GDSC2; CTRP2 1.9168 3.3793 1.9089 22.2994
Kasumi-1 GDSC1; CTRP2 1.9387 4.2261 1.7466 17.3833
SUP-B15 GDSC1; GDSC2; CTRP2 1.9518 4.0492 1.8974 22.2251
CML-T1 GDSC1; GDSC2; CTRP2 1.9592 4.0098 1.8215 17.0364
MHH-PREB-1 GDSC1; GDSC2 1.9689 3.2217 1.9657 25.8744
SU-DHL-6 GDSC1; GDSC2; CTRP2 1.9824 3.5163 1.9708 21.8828
EB2 GDSC1; GDSC2 1.9908 4.1148 1.9311 25.9265
SUP-T1 GDSC1; GDSC2; CTRP2 2.0064 3.5967 1.9917 21.736
GR-ST GDSC1; GDSC2 2.0188 4.208 1.9489 25.7512
Karpas-299 GDSC1; GDSC2; CTRP2 2.0496 3.0089 2.0491 21.4068
RS4;11 GDSC1; GDSC2; CTRP2 2.0636 3.755 2.0416 21.3859
KMS-12-BM GDSC1; GDSC2; CTRP2 2.111 4.1216 2.0578 21.1801
HC-1 GDSC1; GDSC2 2.1114 3.841 2.0852 24.8649
Sc-1 GDSC1 2.1226 4.0732 2.0755 35.7987
CRO-AP2 GDSC1 2.1521 4.1924 1.988 28.1722
OCI-AML-3 GDSC1; GDSC2; CTRP2; CTRP1 2.1691 4.1497 2.1161 20.799
NB4 GDSC1; CTRP2 2.1693 3.4076 2.1651 20.6356
SUP-M2 GDSC1; GDSC2; CTRP2 2.1947 2.9635 2.1947 20.4558
MEG-01 GDSC1; GDSC2 2.2046 3.7314 2.1891 24.1041
A3/Kawakami GDSC1; GDSC2; CTRP2 2.214 3.5488 2.2067 20.3536
MOLM-13 GDSC1; GDSC2; CTRP2 2.2405 4.506 2.1415 20.4877
EB1 CTRP2 2.2493 4.6104 1.9177 14.3506
Reh GDSC1; GDSC2; CTRP2 2.2522 3.8682 2.2299 20.153
SIG-M5 GDSC1; CTRP2 2.2762 4.1969 2.2242 20.0952
MM1.S GDSC2; CTRP2 2.2971 3.9346 2.1731 13.1993
SEM CTRP2 2.3497 3.2808 2.3483 17.9571
OCI-AML-2 GDSC1; GDSC2; CTRP2 2.36 3.9014 2.3397 19.4417
Karpas-620 GDSC1; GDSC2; CTRP2 2.3668 3.9297 2.3448 19.4026
RPMI-6666 GDSC1; GDSC2; CTRP2 2.3713 4.3777 2.3018 19.5323
KE-37 GDSC1; GDSC2; CTRP2 2.3913 3.4464 2.3891 19.177
VAL GDSC1; GDSC2 2.3937 4.0424 2.364 22.7014
Ku812 GDSC1; GDSC2; CTRP2 2.3973 4.0886 2.3636 19.2422
P12-Ichikawa GDSC1; GDSC2; CTRP2 2.4006 3.6411 2.3942 19.1301
P3HR-1 CTRP2 2.4008 3.7649 1.4802 2.3831
MOLT-13 GDSC1; GDSC2; CTRP2 2.4115 4.95 2.239 19.623
MOLT-4 GDSC1; GDSC2 2.4239 3.7193 2.4153 22.3862
SR GDSC1; GDSC2; CTRP2 2.437 3.2393 2.4367 18.8718
RPMI-8866 GDSC1; GDSC2 2.4688 4.0229 2.4441 22.1024
P32/ISH GDSC1; GDSC2 2.4724 3.697 2.4657 22.0045
PL21 CTRP2; CTRP1 2.4778 3.6859 2.4679 17.2121
KMS-26 CTRP2 2.5004 3.8726 2.4795 17.0187
CA46 GDSC1; GDSC2; CTRP2 2.5053 4.2649 2.4591 18.5775
NKM-1 GDSC1; GDSC2 2.5077 3.8353 2.4964 21.7502
ARH-77 GDSC1; GDSC2 2.5111 3.8701 2.4981 21.7305
KMS-20 CTRP2 2.5267 3.135 2.5267 16.7733
RL GDSC1; CTRP2 2.5282 9.7394 0.5025 25.4346
M-07e CTRP2 2.5309 3.1287 2.5308 16.7458
KMS-11 GDSC1; CTRP2; CTRP1 2.5457 4.4314 2.4807 18.3767
L-540 GDSC1; GDSC2; CTRP2 2.5791 6.4335 1.9654 20.1141
MLMA GDSC1; GDSC2 2.5848 3.5205 2.5834 21.117
WIL2 NS GDSC1; GDSC2 2.5905 3.4802 2.5895 21.0715
L-363 GDSC1; GDSC2; CTRP2 2.5917 4.3422 2.5416 18.0255
ML-2 GDSC1; GDSC2 2.6174 3.7514 2.612 20.8809
SU-DHL-8 GDSC1; GDSC2; CTRP2 2.6385 4.1795 2.6086 17.6515
BC-1 GDSC1; GDSC2 2.6577 4.8514 2.528 21.0657
TUR GDSC1; GDSC2 2.6676 3.3723 2.6674 20.474
KOPN-8 GDSC1; GDSC2 2.7064 4.692 2.6115 20.5491
KMOE-2 GDSC1; GDSC2 2.7116 3.7852 2.7069 20.1517
NOMO-1 GDSC1; GDSC2; CTRP2; CTRP1 2.7192 3.737 2.7159 17.0358
ROS-50 GDSC1 2.7227 4.3858 2.6754 29.1452
CTB-1 GDSC1 2.7268 3.6443 2.7252 28.8435
KMS-27 CTRP2 2.7377 5.0129 2.5355 16.0738
BL-41 GDSC1; GDSC2 2.7405 3.8346 2.7349 19.9325
MOLT-16 GDSC1; GDSC2; CTRP2 2.7456 3.835 2.7402 16.87
Karpas-1106P GDSC1; GDSC2 2.7514 5.0087 2.3813 14.811
A4/Fukuda GDSC1; GDSC2; CTRP2 2.7515 3.5705 2.7507 16.8164
KCL-22 GDSC1; GDSC2; CTRP2 2.7531 7.9429 1.5361 21.2202
JVM-3 GDSC1; GDSC2; CTRP2 2.7575 4.153 2.7355 16.8469
AML-193 CTRP2 2.7651 3.3095 2.765 15.1853
KMS-28BM CTRP2 2.7652 4.8579 2.3796 10.9189
BC-3 GDSC1 2.7681 3.4452 2.7679 31.9244
Daudi GDSC1; GDSC2; CTRP2 2.7789 4.032 2.7659 16.6772
VL51 GDSC1; GDSC2 2.782 3.5841 2.7813 19.5934
Kasumi-2 CTRP2 2.8094 3.6946 2.8063 14.9003
ATN-1 GDSC1; GDSC2 2.8103 4.9626 2.67 19.9326
Loucy GDSC1; GDSC2 2.8391 5.6602 2.513 20.4846
KHM-1B CTRP2 2.8399 3.8607 2.4602 3.3858
SUP-HD1 GDSC1; GDSC2; CTRP2 2.8605 4.7639 2.7649 16.4218
JURL-MK1 GDSC1; GDSC2; CTRP2 2.8643 4.1055 2.85 16.1229
OPM-2 GDSC1; GDSC2; CTRP2 2.8737 4.5815 2.8097 16.2279
Farage GDSC1 2.8775 4.2857 2.8498 27.3159
BV-173 GDSC1; GDSC2; CTRP2 2.8849 4.9966 2.7436 16.4203
NCI-H929 GDSC1; GDSC2 2.9135 5.0308 2.5463 13.4509
HPB-ALL CTRP2 2.9558 4.4142 2.75 8.8415
MOLM-16 GDSC1; CTRP2; CTRP1 2.9575 4.9571 2.7926 14.5597
Jurkat GDSC1; GDSC2; CTRP2 2.9608 5.0969 2.571 11.0263
SU-DHL-1 GDSC1; CTRP2 2.9715 3.5584 2.9715 15.3746
IM-9 GDSC1; GDSC2 2.9763 3.8621 2.9487 11.3635
HuNS1 CTRP2 2.9787 6.0213 2.0913 11.5437
LP-1 GDSC1; CTRP2; CTRP1 2.9968 4.2017 2.9812 15.2608
THP-1 GDSC1; CTRP2; CTRP1 3.0066 3.9221 3.0034 15.1554
Mino CTRP2 3.0143 6.3798 2.3615 15.9274
WSU-NHL GDSC1 3.0182 3.9184 3.0153 25.6133
CTV-1 GDSC1; GDSC2 3.0682 4.2136 3.0546 17.4359
OCI-AML-5 GDSC1; GDSC2; CTRP2 3.0755 4.2465 3.06 14.7456
NU-DUL-1 GDSC1; CTRP2; CTRP1 3.0949 4.0876 3.0884 14.5886
OCI-Ly7 GDSC1 3.1059 4.1862 3.0293 15.6976
MV4-11 GDSC1; GDSC2; CTRP2 3.1123 5.3779 2.895 15.2016
EJM GDSC1; GDSC2; CTRP2; CTRP1 3.1327 4.3265 3.1138 14.3826
Ramos.2G6.4C10 GDSC1; GDSC2 3.142 4.9493 3.0333 17.2469
U266B1 GDSC1; GDSC2; CTRP2 3.1685 4.0467 3.1649 14.0978
MOLM-6 CTRP2 3.1708 5.0303 2.1608 4.0693
SK-MM-2 GDSC1; GDSC2; CTRP2 3.1918 4.3165 3.1761 13.9854
Mono-Mac-6 GDSC1; GDSC2; CTRP2 3.1986 4.5019 3.1664 13.9959
MOLT-3 CTRP2 3.2059 4.4403 3.0103 7.0291
JJN-3 GDSC1; GDSC2; CTRP2 3.2111 4.1851 3.2036 13.832
HT GDSC1; CTRP2 3.2247 4.0495 3.2219 13.7279
L-1236 GDSC1; GDSC2 3.2292 4.4951 3.1995 16.2571
RCH-ACV GDSC1; CTRP2 3.2304 4.9602 2.9113 8.8688
Pfeiffer CTRP2 3.2482 4.7232 2.9442 7.1752
PL-21 GDSC1 3.2495 4.567 3.2128 23.2336
MHH-CALL-2 GDSC1; GDSC2 3.2524 4.1945 3.1869 9.2231
KYO-1 CTRP2 3.2542 5.3349 2.6821 8.2679
RPMI-8226 GDSC1; GDSC2; CTRP2; CTRP1 3.2742 4.5269 3.2436 13.4961
Karpas-231 GDSC1; GDSC2 3.2889 3.9941 3.2642 8.7393
SU-DHL-4 GDSC1; CTRP2; CTRP1 3.2893 4.491 3.2633 13.3819
SU-DHL-16 GDSC1 3.3141 4.1136 3.3112 22.3254
BL-70 CTRP2; CTRP1 3.318 6.2946 2.7215 13.7883
Jiyoye GDSC1; GDSC2 3.3584 4.7376 3.3057 15.3522
HL-60 GDSC1; GDSC2; CTRP2 3.3703 5.162 3.2335 13.2324
SU-DHL-10 GDSC1; GDSC2; CTRP2 3.3718 4.3792 3.359 12.7982
EHEB GDSC1; CTRP2 3.3778 4.4303 3.26 7.0454
NU-DHL-1 CTRP2 3.3861 4.2363 3.3756 11.0829
KE-97 CTRP2 3.3907 6.3829 2.7559 13.3753
U-698-M GDSC1; GDSC2 3.3911 5.0446 3.2835 15.3221
Mono-Mac-1 CTRP2 3.4053 8.2588 1.4092 13.4721
L-428 GDSC1; GDSC2; CTRP2 3.4133 5.5287 3.1791 13.297
GDM-1 GDSC1; GDSC2; CTRP2; CTRP1 3.4189 5.6115 3.1594 13.3517
SET-2 CTRP2 3.4234 5.3385 3.1871 11.6394
QIMR-WIL GDSC1 3.4269 4.621 3.3946 21.2384
Hs 445 GDSC1; GDSC2 3.4532 4.4675 3.4373 14.4755
AMO1 GDSC1; GDSC2; CTRP2; CTRP1 3.4574 4.2165 3.4543 12.2062
WSU-DLCL2 GDSC1; GDSC2; CTRP2; CTRP1 3.476 4.0671 3.4755 12.0763
Namalwa GDSC1; GDSC2; CTRP2 3.4768 4.4105 3.4658 12.1056
BALL-1 GDSC1; GDSC2 3.4829 5.1227 3.3656 14.6549
EM-2 GDSC1; GDSC2; CTRP2 3.4886 4.1185 3.4876 11.9954
HDLM-2 GDSC1; GDSC2; CTRP2 3.5141 4.7322 3.4731 11.9621
KY821 GDSC1; GDSC2 3.515 4.7553 3.4708 14.1107
YT GDSC1; GDSC2 3.5177 4.9458 3.4414 14.2188
Karpas-422 GDSC1; GDSC2; CTRP2 3.5653 7.3212 2.6425 14.9071
TK [Human B-cell lymphoma] GDSC1; GDSC2 3.5756 4.6901 3.5442 13.5925
ME1 CTRP2 3.5901 6.5273 2.9015 12.2745
Ri-1 CTRP2 3.6 6.3378 2.5341 8.0483
HAL-01 GDSC1; GDSC2 3.6142 4.8057 3.5696 13.347
SCC-3 GDSC1; GDSC2 3.6146 4.1926 3.6138 13.172
Raji GDSC1; GDSC2; CTRP2 3.6149 6.2033 3.1614 12.791
MOLP-2 CTRP2 3.6817 4.6172 3.6484 9.1915
HEL GDSC1; CTRP2 3.6873 4.4981 3.6786 10.721
K-562 GDSC1; GDSC2; CTRP2 3.6887 5.3222 3.5395 11.1959
P31/FUJ GDSC1; GDSC2; CTRP2 3.7066 4.1162 3.7065 10.5665
F-36P CTRP2 3.753 5.4298 3.5137 9.4627
MN-60 GDSC1; GDSC2 3.7779 5.1879 3.6715 12.3366
DG-75 GDSC1; GDSC2 3.866 5.2823 3.7436 11.724
U-937 CTRP2; CTRP1 3.8839 5.119 3.7596 8.2567
KMS-34 CTRP2 3.8971 4.9352 3.4961 3.0753
SUP-B8 GDSC1 3.9538 5.4085 3.448 8.3526
SKM-1 GDSC1; CTRP2; CTRP1 4 5.1666 3.8721 7.4987
LAMA-84 GDSC1; GDSC2; CTRP2 4.0548 6.0224 3.7002 9.5625
TF-1 CTRP2 4.1111 6.5851 2.8583 5.4699
MC116 GDSC1; CTRP2 4.2015 4.5612 4.2012 7.3298
OCI-Ly3 CTRP2 4.3768 7.9172 2.4081 6.9624
H9 GDSC1; GDSC2 4.4094 9.5692 2.3969 16.3072
JVM-2 GDSC1; GDSC2; CTRP2 4.417 5.4092 4.3092 6.2929
ME1 GDSC1; GDSC2 4.4294 6.2523 3.9979 8.7622
RC-K8 GDSC1; GDSC2 4.433 5.3609 4.3409 7.2308
OCI-M1 GDSC1; GDSC2; CTRP2 4.4382 5.0342 4.4181 5.8477
KG-1 GDSC1; GDSC2 4.4773 5.6063 4.3094 7.2148
Granta-519 GDSC1; GDSC2; CTRP2 4.5067 5.5424 4.3636 5.8358
MHH-CALL-3 CTRP2 4.9558 8.142 3.4212 6.9953
CMK GDSC1; CTRP2 5.1109 8.1968 2.9961 4.4353
HEL 92.1.7 CTRP2 5.1604 9.0318 2.4423 5.4433
KMS-18 CTRP2 5.8953 10.8387 2.0735 5.9098
KMM-1 CTRP2 6.0518 11.7365 1.7501 7.0303
Toledo CTRP2 6.0756 8.0902 3.4009 0.7066
Ci-1 CTRP2 6.1167 7.3347 4.6215 0.4983
JeKo-1 GDSC1; CTRP2 6.3976 10.7943 3.2041 5.477
REC-1 CTRP2 7.218 9.4023 3.3773 0.2971
HD-MY-Z CTRP2 7.9768 15.9928 0.9791 7.4927
KM-H2 GDSC1; GDSC2; CTRP2 8.5021 16.2617 2.2208 7.7541
⏷ Show the Full List of 218 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 3.3471 5.1239 2.8716 7.2053
TE15 CTRP2 6.8544 9.5513 4.0606 1.6852
OE21 GDSC1; GDSC2; CTRP2 3.0327 4.5409 2.9855 15.1315
KYSE-450 GDSC1; GDSC2; CTRP2 3.0383 4.1195 3.0289 14.9687
KYSE-180 GDSC1; GDSC2; CTRP2 3.0667 7.5976 2.0092 18.6249
OE33 GDSC1; GDSC2; CTRP2 3.1254 4.5782 3.0794 14.5209
KYSE-270 GDSC1; GDSC2 3.8699 4.7798 3.8457 11.2944
KYSE-510 GDSC1; CTRP2 4.0582 5.3406 3.9376 8.681
KYSE-520 GDSC1; GDSC2; CTRP2 4.1829 5.4566 4.0397 7.9478
KYSE-410 GDSC1; GDSC2; CTRP2 4.3018 5.7934 4.0519 7.5651
KYSE-70 GDSC1; GDSC2; CTRP2 4.3067 5.3323 4.2111 6.9693
T.T GDSC1; GDSC2 4.3067 5.7199 4.0845 8.7609
TE-14 CTRP2 4.4612 6.0203 4.0136 5.6076
TE-15 GDSC1; GDSC2 4.7925 6.3613 4.3147 6.2289
TE-10 GDSC1; CTRP2 4.9627 7.6251 3.8588 6.7557
TE-4 GDSC1; GDSC2; CTRP2 4.9776 9.04 3.1687 9.5577
COLO 680N GDSC1; GDSC2; CTRP2 5.2154 6.7937 4.4955 3.6178
KYSE-150 GDSC1; GDSC2; CTRP2 5.287 8.4332 3.7371 6.6069
TE-1 GDSC1; GDSC2; CTRP2 5.4105 7.8197 4.146 4.6879
KYSE-30 CTRP2 6.0259 7.743 4.3987 1.3048
TE-5 GDSC1; GDSC2; CTRP2 6.0813 9.318 3.9159 4.5119
TE-8 GDSC1; GDSC2 6.2899 9.4098 4.0176 4.4818
TE-11 GDSC1; CTRP2 6.7688 8.4509 4.7355 0.7045
EC-GI-10 GDSC1; GDSC2; CTRP2 7.0967 8.9003 4.707 0.5848
OE19 GDSC1; GDSC2; CTRP2 7.2305 12.9705 2.9475 6.6946
TE-9 GDSC1; GDSC2; CTRP2 7.4858 11.575 3.7616 3.3108
TE-6 GDSC1; GDSC2; CTRP2 7.9301 9.7946 4.7143 0.251
KYSE-140 GDSC1; GDSC2; CTRP2 8.7834 13.2832 3.7217 2.2665
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 7.7543 21.9688 -2.0123 17.8039
MZ-PC-1 GDSC1 2.2112 4.2568 2.1475 34.9054
PaTu 8988s CTRP2 2.8658 9.1299 0.4876 18.6465
Panc 03.27 GDSC1; GDSC2; CTRP2 2.8954 3.8476 2.8922 15.8826
PSN1 GDSC1; GDSC2; CTRP2 2.8957 8.8753 1.266 21.8299
KP-1N GDSC1; GDSC2 2.9673 4.3986 2.822 11.9623
QGP-1 GDSC1 3.1381 5.5463 2.8738 25.7973
SNU-213 CTRP2 3.1809 4.8982 2.8005 7.9673
HuP-T4 GDSC1; GDSC2; CTRP2 3.1982 5.5547 2.9367 14.799
SUIT-2 GDSC1; GDSC2; CTRP2 3.5146 5.0002 3.4272 12.117
BxPC-3 GDSC1; GDSC2; CTRP2 3.5519 4.677 3.5206 11.6819
YAPC GDSC1; GDSC2; CTRP2 3.6121 5.1829 3.492 11.5936
PaTu 8902 GDSC1; GDSC2; CTRP2; CTRP1 3.7947 4.2851 3.7942 9.9917
CFPAC-1 GDSC1; GDSC2; CTRP2 4.1028 4.875 4.0815 8.0453
SNU-410 CTRP2 4.2048 5.9094 3.2724 3.4245
SU.86.86 GDSC1; GDSC2; CTRP2 4.2499 5.5461 4.0839 7.5931
HuP-T3 GDSC1; GDSC2; CTRP2 4.3386 5.6134 4.1571 7.072
DAN-G GDSC1; GDSC2; CTRP2 4.3596 5.1034 4.3222 6.4204
Panc 08.13 GDSC1; GDSC2; CTRP2 4.4358 6.0357 4.0971 7.0319
Panc 10.05 GDSC1; GDSC2 4.4585 8.0646 3.1781 12.529
KP-3 GDSC1; GDSC2; CTRP2 4.5044 6.0355 4.1688 6.5761
TCC-Pan2 CTRP2 4.5459 6.8899 3.0475 3.8045
AsPC-1 GDSC1; GDSC2; CTRP2 4.5459 6.517 3.9979 7.138
PaTu 8988t GDSC1; GDSC2; CTRP2 4.7427 6.0054 4.4277 4.9584
Capan-1 GDSC1; GDSC2; CTRP2 4.9458 5.9314 4.6662 3.5149
HPAF-II GDSC1; CTRP2 5.104 6.6324 4.4772 3.9225
KP-4 GDSC1; GDSC2; CTRP2 5.1126 5.8586 4.864 2.3279
Panc 04.03 GDSC1; GDSC2; CTRP2 5.1473 6.5497 4.5571 3.5039
HPAC GDSC1; GDSC2; CTRP2 5.2824 7.1256 4.387 3.9342
KP-2 GDSC1; GDSC2; CTRP2 5.319 7.4219 4.2695 4.349
PL4 GDSC1; GDSC2 5.3229 7.3633 4.3021 4.9608
Hs 766T GDSC1; GDSC2; CTRP2 5.5197 6.9985 4.6422 2.452
PK-59 CTRP2 5.6083 9.6105 2.4672 4.6689
Capan-2 GDSC1; GDSC2; CTRP2 5.6685 6.9992 4.7517 1.7723
Panc 05.04 CTRP2 5.7957 10.3112 2.2581 5.2798
PK-45H CTRP2 6.5541 8.6441 3.3932 0.4882
L3.3 CTRP2 6.9719 11.2562 3.3601 4.1074
MIA PaCa-2 GDSC1; GDSC2; CTRP2 7.3119 9.1319 4.7111 0.4694
Panc 02.03 GDSC1; GDSC2; CTRP2 7.4322 14.0216 2.5803 7.8262
SW1990 GDSC1; GDSC2; CTRP2 7.5406 9.7021 4.5898 0.6416
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 75 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 1.5628 2.5763 1.559 17.9785
Hs 940.T GDSC1; CTRP2 0.7415 1.9099 0.7413 29.9619
Hs 934.T CTRP2 1.5604 2.0587 1.5604 23.2107
IGR-39 CTRP2 1.5667 3.4641 1.5364 23.2707
Hs 936.T CTRP2 1.8488 2.398 1.8488 15.9298
Hs 852.T CTRP2; CTRP1 1.9755 3.8893 1.9263 20.6881
SK-MEL-30 GDSC1; CTRP2 1.9853 2.6579 1.9853 21.8256
MZ-MEL-7 GDSC1 2.2201 3.0557 2.2199 34.466
SK-MEL-3 GDSC1; CTRP2 2.295 2.9112 2.295 19.7996
Hs 688(A).T CTRP2 2.4833 2.9583 2.4833 17.0623
M14 GDSC1; GDSC2 2.4968 3.2125 2.4967 21.7907
Mel JuSo GDSC1; GDSC2; CTRP2 2.5287 3.5915 2.5257 18.2808
IGR-1 GDSC1; GDSC2; CTRP2 2.6738 3.4723 2.6733 17.3239
WM35 GDSC1; GDSC2 2.6865 3.5005 2.6859 20.3296
WM278 GDSC1; GDSC2 2.7478 4.0019 2.7354 19.9027
IPC-298 GDSC1; CTRP2 2.7724 3.2899 2.7724 16.6768
WM1552C GDSC1; GDSC2 2.7812 3.4059 2.7811 19.5974
HMV-II GDSC1; GDSC2 2.7969 3.5517 2.7965 19.4774
SH-4 GDSC1; GDSC2 2.8268 3.4937 2.8267 19.2456
UACC-257 GDSC1; GDSC2; CTRP2 3.1577 3.8811 3.1568 14.1594
IGR-37 GDSC1; GDSC2; CTRP2 3.1634 4.1591 3.1557 14.1449
WM115 GDSC1; GDSC2; CTRP2 3.2136 3.6979 3.2136 13.7908
RVH-421 GDSC1; CTRP2 3.2225 4.558 3.1853 13.8562
MDA-MB-435S CTRP2 3.2793 4.29 3.1429 6.2721
RPMI-7951 GDSC1; GDSC2; CTRP2 3.4044 4.3727 3.3932 12.5799
Hs 895.T CTRP2 3.4602 3.9919 3.4264 4.5881
Hs 839.T CTRP2 3.5336 4.7973 3.456 10.3324
COLO 792 GDSC1; GDSC2; CTRP2 3.5579 7.8649 2.3914 15.9004
Mel Ho GDSC1; CTRP2 3.6455 4.14 3.6453 10.9666
G-361 GDSC1; GDSC2; CTRP2 3.6548 4.3187 3.6524 10.9129
G-mel GDSC1 3.6727 6.0218 3.2921 20.6143
LB373-MEL-D GDSC1 3.682 4.2122 3.6815 18.2242
COLO 829 GDSC1; GDSC2; CTRP2 3.7279 4.9478 3.6683 10.6271
COLO 741 CTRP2 3.7301 4.8167 3.3945 3.9358
MMAc-SF GDSC1 3.7392 4.2559 3.7386 17.589
WM983B CTRP2 3.7555 11.6617 0.6085 20.7686
IST-MEL1 GDSC1; GDSC2 3.8356 5.0821 3.7585 11.7716
COLO 679 GDSC1; GDSC2 3.8607 5.3522 3.7188 11.8464
CP50-MEL-B GDSC1 3.8904 4.4192 3.8892 15.9123
WM1799 CTRP2 3.8934 4.4961 3.7052 2.1632
MeWo GDSC1; GDSC2; CTRP2 4.031 4.8907 4.0031 8.5369
LOX-IMVI GDSC1; GDSC2; CTRP2 4.0874 5.0402 4.0398 8.2354
HT-144 GDSC1; GDSC2; CTRP2 4.0882 4.8451 4.0695 8.1319
COLO 783 GDSC1 4.1057 4.925 4.0781 13.6698
SK-MEL-2 GDSC1; GDSC2; CTRP2 4.1333 10.5509 1.661 17.3708
A2058 GDSC1; GDSC2; CTRP2 4.1391 5.4278 4.0007 8.2163
A-375 GDSC1; GDSC2; CTRP2; CTRP1 4.1574 5.4397 4.017 8.1044
A101D GDSC1; GDSC2; CTRP2 4.1625 4.7162 4.1575 7.6007
GAK GDSC1; GDSC2 4.2204 4.9576 4.1962 8.5911
SK-MEL-28 GDSC1; CTRP2; CTRP1 4.2219 4.3165 4.2219 7.1952
Hs 938.T GDSC1 4.3104 5.0604 4.2769 11.4301
WM793 GDSC1; GDSC2; CTRP2 4.34 5.0821 4.305 6.5403
MZ-MEL-2 GDSC1 4.3862 5.3193 4.3014 10.8913
SK-MEL-24 GDSC1; GDSC2; CTRP2 4.4344 5.1704 4.3901 5.9551
VMRC-MELG GDSC1 4.4945 5.2607 4.4349 9.5388
A-431 GDSC1 4.5141 6.0034 4.1925 10.9725
451Lu GDSC1 4.5755 5.392 4.4871 8.814
COLO 800 GDSC1; CTRP2 4.6878 6.5242 4.1355 6.2475
SK-MEL-1 GDSC1; GDSC2; CTRP2; CTRP1 4.7166 6.5964 4.1297 6.2018
LB2518-MEL GDSC1 4.8408 5.2675 4.8106 5.5201
SK-MEL-5 GDSC1; CTRP2; CTRP1 4.88 6.4212 4.3713 4.8498
SK-MEL-31 GDSC1; CTRP2 4.9255 6.6266 4.1521 3.9864
A-388 GDSC1 4.961 6.5145 4.4034 7.7035
CHL-1 GDSC1; GDSC2 5.0698 6.051 4.7307 3.4952
Hs 944.T CTRP2 5.5579 10.0083 2.2446 5.6813
WM266-4 CTRP2 5.5959 6.9564 3.6317 0.3696
K029AX CTRP2 5.7603 7.4541 3.5103 0.593
WT2-iPS GDSC1; GDSC2; CTRP2 6.2928 8.0027 4.6781 1.2851
UACC-62 GDSC1; GDSC2; CTRP2 6.6727 9.6064 4.1734 2.7086
CP66-MEL GDSC1 6.786 8.9717 4.5244 2.2834
CJM [Human melanoma] CTRP2 7.1744 8.6815 4.5538 0.2002
HMCB CTRP2 7.8591 16.1633 0.8284 8.2001
WM88 CTRP2 7.8716 12.7695 3.2059 3.6763
DJM-1 GDSC1 7.9762 9.774 4.739 0.3914
EquiPSC Line K2 GDSC1 5.0338 6.824 4.319 8.0165
⏷ Show the Full List of 75 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-26 GDSC1; GDSC2 2.5918 3.7228 2.5867 21.0777
OACP4 C GDSC1; GDSC2 3.3613 5.0939 3.2399 15.6084
KYAE-1 GDSC1; GDSC2 3.4119 4.7907 3.3548 14.9573
OACM5.1 C GDSC1; GDSC2 3.7732 5.5513 3.564 12.8043
SK-GT-4 GDSC1; GDSC2 3.904 5.0498 3.8394 11.1932
FLO-1 GDSC1; GDSC2 4.2304 5.3967 4.1095 8.9118
KYSE-220 GDSC1; GDSC2 4.5183 5.7831 4.2867 7.1808
ESO-51 GDSC1; GDSC2 4.5235 5.9185 4.2376 7.3839
KYSE-50 GDSC1; GDSC2 5.2355 6.3836 4.7174 3.141
TE-12 GDSC1 5.4167 7.7912 4.1653 7.8058
HCE-4 GDSC1 6.5079 9.3979 4.1672 4.9722
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 3.603 5.2597 3.4627 11.7241
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NH-6 CTRP2 1.5998 2.202 1.5997 17.7019
GI-ME-N GDSC1; GDSC2 2.0297 3.6289 2.014 25.4541
CHP-134 GDSC1; GDSC2 2.1394 3.0824 2.1389 24.549
CHP-126 GDSC1; CTRP2 2.1696 4.0262 2.13 20.7513
Kelly GDSC1; GDSC2; CTRP2 2.1881 3.5021 2.1818 20.5197
KP-N-YS GDSC1 2.337 4.4338 2.2569 37.7608
IMR-5 GDSC1; GDSC2 2.524 3.9335 2.5079 21.6431
SK-N-AS GDSC1; GDSC2; CTRP2 2.6766 4.1777 2.6487 17.396
NB(TU)1 GDSC1; GDSC2 2.9723 4.7807 2.8827 18.4778
GOTO GDSC1; GDSC2 2.9791 5.4172 2.7384 19.0483
SiMa GDSC1; GDSC2 3.1394 4.2181 3.128 16.8779
MHH-NB-11 GDSC1; CTRP2 3.1989 4.4153 3.1755 13.9644
KP-N-SI9s CTRP2 3.2898 5.2079 2.7757 7.7706
IMR-32 CTRP2 3.343 20.2968 -4.6456 31.766
SJNB-17 GDSC1 3.5355 5.2772 3.3844 23.3155
NB1 GDSC1; GDSC2; CTRP2 3.584 5.5134 3.3697 12.1119
LA-N-6 GDSC1 3.7316 5.4444 3.5514 18.7286
KP-N-YN GDSC1; GDSC2; CTRP2 4.293 6.6805 3.669 9.0601
CHP-212 GDSC1; GDSC2; CTRP2 4.4019 7.264 3.5076 9.4353
TGW GDSC1; GDSC2 4.465 5.2799 4.3979 6.88
SJNB-13 GDSC1; GDSC2 4.4716 5.403 4.3706 6.971
NH-12 GDSC1; GDSC2 4.4982 5.6423 4.3188 7.1046
SJNB-6 GDSC1 4.5627 5.4119 4.4672 8.999
SJNB-12 GDSC1; GDSC2 4.5745 5.6637 4.3928 6.5293
SJNB-7 GDSC1; GDSC2 4.5862 5.4003 4.4963 6.0423
SJNB-5 GDSC1 4.7489 5.4089 4.6708 6.8289
SK-N-MC-IXC GDSC1 4.7954 5.2029 4.7749 5.9673
SK-N-BE(2) CTRP2 4.7999 6.0735 4.3142 3.5763
SJNB-10 GDSC1; GDSC2 4.8312 5.5554 4.7085 4.3022
SK-N-SH GDSC1; GDSC2; CTRP2 4.9103 8.8203 3.2188 9.4898
NB69 GDSC1; GDSC2 5.0246 7.4255 4.0131 7.0662
SK-N-BE(2)-M17 GDSC1; GDSC2 5.262 6.4298 4.7173 3.0793
SK-N-DZ GDSC1; GDSC2; CTRP2 5.2836 7.5055 4.198 4.7118
SK-N-FI GDSC1; GDSC2; CTRP2 6.9323 8.9891 4.5928 1.0083
SJNB-14 GDSC1; GDSC2 7.5915 9.3511 4.7436 0.3528
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 2.9465 4.3353 2.9024 14.1259
HuCC-T1 GDSC1; GDSC2; CTRP2 3.7302 4.4476 3.7253 10.4277
SNU-478 CTRP2 3.7864 4.8167 3.7263 8.5876
SNU-869 CTRP2 4.0702 6.7746 3.2761 9.5545
SNU-1196 CTRP2 6.1667 8.2848 4.2364 1.7446
SNU-308 CTRP2 6.1861 7.7472 3.5767 0.257
HuH-28 CTRP2 6.3609 11.0641 3.0486 6.1562
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 89 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-468 GDSC1; GDSC2; CTRP2 1.6822 2.5809 1.6821 23.8085
COLO 824 GDSC1; GDSC2 2.6581 4.408 2.6038 20.759
Evsa-T GDSC1; GDSC2 2.7563 3.4005 2.7562 19.7891
CAL-148 GDSC1; GDSC2; CTRP2 2.8091 4.3332 2.773 16.5565
HCC1500 GDSC1; GDSC2; CTRP2 2.8439 4.2612 2.8168 16.2988
KPL-1 CTRP2 2.8852 4.1023 2.8632 14.459
BT-474 GDSC1; GDSC2; CTRP2 3.0765 4.0176 3.072 14.7027
BT-549 GDSC1; GDSC2; CTRP2 3.1844 4.3311 3.1673 14.0382
HCC70 GDSC1; GDSC2 3.2 4.4586 3.1725 16.474
HCC1599 GDSC1 3.2431 4.0885 3.2397 26.0069
HCC202 GDSC1; CTRP2 3.2557 4.6666 3.2062 13.6808
HCC1395 GDSC1; GDSC2; CTRP2 3.2593 4.5373 3.2267 13.6003
MDA-MB-453 GDSC1; GDSC2; CTRP2 3.3343 4.3441 3.3223 13.0413
HCC1569 GDSC1 3.3966 6.298 2.892 24.393
MCF-7 GDSC1; GDSC2; CTRP2; CTRP1 3.4102 5.3633 3.2242 13.145
ZR-75-1 CTRP2 3.4181 5.437 2.7973 7.3377
DU4475 GDSC1; GDSC2 3.5069 4.4213 3.4964 14.0399
T-47D GDSC1; GDSC2; CTRP2 3.5416 4.4145 3.5327 11.6748
HCC1806 GDSC1; GDSC2; CTRP2 3.7383 4.2667 3.7376 10.3612
OCUB-M GDSC1 3.7484 4.5885 3.7361 17.5528
HCC2218 GDSC1; CTRP2 3.9816 5.0116 3.9307 8.9385
HCC1937 GDSC1; GDSC2; CTRP2 3.9876 9.31 2.1301 15.8908
EFM-19 GDSC1; GDSC2 4.0015 5.3756 3.8659 10.7358
HCC1143 GDSC1; GDSC2; CTRP2 4.0047 6.2652 3.0747 6.1865
YMB-1-E GDSC1 4.0072 5.154 3.9293 16.939
AU565 GDSC1; GDSC2 4.0648 5.4638 3.9087 10.3351
ZR-75-30 GDSC1; GDSC2; CTRP2 4.1438 5.3609 4.0254 8.1142
HCC1428 GDSC1; GDSC2; CTRP2 4.1456 5.3773 4.0226 8.1188
HCC1419 GDSC1; GDSC2; CTRP2 4.2241 5.5834 4.0434 7.8152
BT-483 GDSC1; GDSC2 4.2705 4.9983 4.2439 8.2145
HCC38 GDSC1; GDSC2; CTRP2 4.3443 5.4525 4.2167 6.8387
EFM-192A GDSC1; GDSC2 4.4906 6.2369 4.0676 8.2579
CAL-85-1 GDSC1; GDSC2; CTRP2 4.5477 7.6606 3.458 9.2973
HCC1187 GDSC1; GDSC2 4.6282 6.0832 4.2762 6.8865
MFM-223 GDSC1; GDSC2 4.6645 5.315 4.6064 5.306
HCC1954 GDSC1; GDSC2; CTRP2 4.7477 6.5339 4.1896 5.889
CAL-120 GDSC1; GDSC2 4.7875 6.1464 4.4095 5.7992
MRK-nu-1 GDSC1; GDSC2 4.8059 7.3861 3.8335 8.485
HCC2157 GDSC1 4.8594 6.6178 4.2573 9.0991
MDA-MB-231 GDSC1; GDSC2; CTRP2 4.8688 7.2689 3.9491 6.5872
UACC-893 GDSC1 4.8798 6.9913 4.0952 10.1363
MDA-MB-330 GDSC1 4.9256 6.3998 4.4253 7.6893
MDA-MB-436 GDSC1; GDSC2 4.966 5.7577 4.7654 3.6253
UACC-812 GDSC1; GDSC2 5.0766 7.8788 3.8337 7.8095
HDQ-P1 GDSC1; GDSC2 5.0997 7.8918 3.8474 7.6876
CAMA-1 GDSC1; GDSC2; CTRP2 5.155 6.1797 4.7471 2.7088
MDA-MB-415 GDSC1; GDSC2 5.3097 6.9186 4.5134 3.962
MDA-MB-157 GDSC1; GDSC2; CTRP2 5.3796 6.6862 4.6872 2.5121
JIMT-1 GDSC1; GDSC2; CTRP2 5.5163 7.5812 4.3499 3.658
MDA-MB-361 GDSC1; GDSC2; CTRP2 5.5667 7.2262 4.5653 2.6885
MDA-MB-175-VII GDSC1; GDSC2 5.9515 7.5405 4.6831 1.9512
CAL-51 GDSC1; GDSC2; CTRP2 6.8559 8.6904 4.6793 0.807
Hs 578T GDSC1; GDSC2 7.012 9.0171 4.6205 1.026
HMC-1-8 CTRP2 7.0553 8.4997 4.5735 0.2008
BT-20 GDSC1; GDSC2; CTRP2 7.7996 12.6095 3.4773 3.9977
BT 286 CTRP2 1.4983 6.6045 0.6592 26.5596
BT 330 CTRP2 2.3976 3.5171 2.392 17.6519
BT 504 CTRP2 2.9247 4.697 2.8158 14.4967
BT 271 CTRP2 2.9309 4.8041 2.7987 14.5379
BT 440 CTRP2 3.1574 4.3302 3.1271 12.6737
BT147 CTRP2 3.1675 19.9446 -4.0224 33.516
BT 131 CTRP2 3.1757 3.9034 3.1733 12.4576
BT 444 CTRP2 3.246 4.1297 3.2369 12.0115
BT 333 CTRP2 3.2795 4.137 3.2711 11.7864
BT 239 CTRP2 3.3985 4.145 3.3932 10.9827
BT 428 CTRP2 3.4484 4.322 3.4343 10.6802
BT 422 CTRP2 3.4957 4.4032 3.4767 10.3815
BT 232 CTRP2 3.5041 4.1496 3.501 10.272
BT 245 CTRP2 3.5329 4.3067 3.5234 10.1016
BT 498 CTRP2 3.557 4.2269 3.5524 9.9246
BT 340 CTRP2 3.6288 4.4787 3.6094 9.4963
BT 228 CTRP2 3.7138 4.4894 3.6979 8.9184
BT 248 CTRP2 3.7415 4.8684 3.6664 8.9392
BT 172 CTRP2 3.7774 4.4274 3.7693 8.4681
BT 482 CTRP2 3.7774 4.2889 3.7754 8.4479
BT 416 CTRP2 3.9001 16.8912 -1.8577 27.6942
BT 216 CTRP2 3.9729 6.663 3.2306 9.98
BT 359 CTRP2 4.1098 5.2324 3.9676 6.7329
BT 231 CTRP2 4.148 5.3131 3.9815 6.5697
BT 159 CTRP2 4.4745 5.415 4.2929 4.4653
BT 328 CTRP2 4.5708 6.0383 4.1132 4.9357
BT 139 CTRP2 4.7838 5.3566 4.64 2.2801
BT 145 CTRP2 5.424 6.997 3.538 0.7322
BT164 CTRP2 5.7293 6.9954 3.6716 0.2307
BT 112 CTRP2 5.891 7.1925 3.663 0.196
BT 187 CTRP2 6.0434 8.4848 4.0684 2.5273
BT 179 CTRP2 6.1046 7.2438 3.7228 0.0746
BT 224 CTRP2 6.9477 8.4098 3.6217 0.0639
BT 320 CTRP2 7.8254 25.9992 -3.2152 23.6405
⏷ Show the Full List of 89 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 4.6292 7.5041 3.4535 7.534
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GOS-3 CTRP2 0.8782 2.579 0.8711 27.7793
AM-38 GDSC1; GDSC2; CTRP2 1.5468 4.0178 1.4711 24.9452
GMS-10 CTRP2 1.6242 6.184 0.6356 21.4051
Hs 683 GDSC1; CTRP2 1.7001 2.0834 1.7001 23.6911
42-MG-BA GDSC1; GDSC2; CTRP2 2.3429 3.0288 2.3429 19.4862
SF539 GDSC1; GDSC2; CTRP2 2.431 2.9701 2.431 18.9103
KNS-60 CTRP2 2.4919 3.1322 2.4895 11.3624
KNS-81 CTRP2 2.562 2.9999 2.5618 10.8557
KINGS-1 GDSC1; GDSC2 2.617 3.6637 2.6137 20.8759
GaMG GDSC1; GDSC2; CTRP2; CTRP1 2.6485 3.0628 2.6485 17.4873
CAS-1 GDSC1; GDSC2; CTRP2 2.6947 3.5108 2.6941 17.1874
KG-1-C CTRP2 2.7004 3.1141 2.7004 15.6163
SNU-466 CTRP2 2.7653 3.2467 2.7653 15.1838
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 2.8279 4.3794 2.7877 19.3938
KNS-81-FD GDSC1 2.9024 4.0234 2.8936 26.9325
GI-1 GDSC1; GDSC2 2.9599 3.8896 2.9567 18.2308
D-336MG GDSC1 2.9699 4.2289 2.9513 26.2373
SF268 GDSC1; GDSC2; CTRP2 3.0141 4.1492 3.0024 15.1344
NMC-G1 GDSC1 3.2439 4.4005 3.224 23.2011
MOG-G-CCM GDSC1; GDSC2 3.3755 4.3621 3.3639 15.0582
ONS-76 GDSC1; GDSC2; CTRP2 3.3815 4.1198 3.3794 12.6997
M059K CTRP2 3.4033 8.6638 1.2067 14.3526
KALS-1 GDSC1; GDSC2; CTRP2 3.4036 4.6815 3.3622 12.6859
8-MG-BA GDSC1; GDSC2; CTRP2 3.426 9.7417 1.385 20.0605
Daoy GDSC1; GDSC2; CTRP2 3.4667 4.3261 3.4599 12.1576
MOG-G-UVW GDSC1; GDSC2 3.5297 4.7006 3.494 13.9639
SNU-201 CTRP2 3.58 4.2061 3.5766 9.7673
SNU-626 CTRP2 3.6071 4.1332 3.6059 9.5795
SNU-489 CTRP2 3.61 4.0887 3.6094 9.5581
LN-229 GDSC1; GDSC2; CTRP2; CTRP1 3.6207 4.021 3.6206 11.1283
SNB-75 GDSC1; CTRP2 3.6276 4.8061 3.5839 11.2289
A-172 GDSC1; GDSC2; CTRP2 3.6413 4.2208 3.6404 10.9965
D-423MG GDSC1 3.7977 4.6389 3.7836 17.0149
U-118MG GDSC1; GDSC2; CTRP2 3.7987 4.6417 3.7845 10.0105
DK-MG GDSC1; GDSC2; CTRP2 3.8203 4.9896 3.7605 10.0235
SF295 GDSC1; CTRP2 3.8422 4.6002 3.8328 9.7101
D-247MG GDSC1 3.8544 5.9935 3.4974 18.4653
U-251MG GDSC1; GDSC2; CTRP2 3.9373 4.751 3.9201 9.114
CCF-STTG1 CTRP2 3.9582 5.2468 3.3968 3.378
YKG-1 GDSC1; CTRP2 3.9602 5.3242 3.8352 9.3367
LN-405 GDSC1; GDSC2 4.0383 4.6958 4.0302 9.9325
PFSK-1 GDSC1 4.045 5.7 3.8095 15.5979
KNS-42 GDSC1; CTRP2 4.0899 4.8415 4.0717 8.1192
DBTRG-05MG GDSC1; GDSC2; CTRP2 4.2403 5.2712 4.1549 7.3671
H4 GDSC1; GDSC2 4.257 5.0607 4.2193 8.3631
GB-1 GDSC1; GDSC2; CTRP2 4.3015 6.6874 3.6744 9.0179
M059J GDSC1; GDSC2 4.335 5.1883 4.2782 7.8393
YH-13 GDSC1; GDSC2; CTRP2 4.3583 5.0287 4.3334 6.3866
SNU-1105 CTRP2 4.3736 14.7906 -1.0276 20.7808
D-566MG GDSC1 4.3763 5.3944 4.2692 11.1363
U-87MG ATCC GDSC1; GDSC2; CTRP2 4.3786 5.0001 4.3591 6.2354
D-392MG GDSC1; GDSC2 4.4253 5.6465 4.2389 7.6945
LNZTA3WT4 GDSC1; GDSC2 4.5487 5.3149 4.48 6.242
SF126 GDSC1; CTRP2 4.6404 5.4844 4.5282 4.8514
SW1783 GDSC1; GDSC2; CTRP2 4.6573 6.3265 4.1966 6.0792
LN-18 GDSC1; GDSC2; CTRP2 4.6785 5.0116 4.6742 4.2228
Onda 10 GDSC1 4.6989 5.9809 4.3936 8.8381
Onda 11 GDSC1 4.7228 5.9164 4.4462 8.3868
D-502MG GDSC1 4.7893 5.7555 4.5838 7.1917
SK-MG-1 GDSC1; GDSC2 5.0623 6.9444 4.2853 5.6565
SW1088 GDSC1; GDSC2; CTRP2 5.1301 7.1777 4.2297 4.8851
D-542MG GDSC1 5.552 7.7214 4.3081 6.3997
TM-31 CTRP2 5.7318 11.7276 2.257 10.3974
SNU-738 CTRP2 5.9239 8.1114 4.1673 2.2945
D-263MG GDSC1; GDSC2 6.4107 9.4412 4.0837 3.9823
Becker GDSC1; GDSC2; CTRP2 7.2243 9.6754 4.4517 1.2183
D283 Med GDSC1; GDSC2; CTRP2 7.346 8.7103 4.8797 0.153
T98G GDSC1; GDSC2; CTRP2 10.5431 19.0626 2.1602 5.7365
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1; GDSC2 1.5153 2.9826 1.5108 29.378
TGBC1TKB GDSC1; GDSC2 4.9145 5.4862 4.8237 3.5232
TGBC24TKB GDSC1; GDSC2 5.0995 6.4802 4.5484 4.2927
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 GDSC1; GDSC2; CTRP2 2.7644 3.7335 2.7617 16.7383
EN GDSC1; GDSC2; CTRP2 3.3847 4.417 3.3697 12.7211
KLE GDSC1; GDSC2; CTRP2; CTRP1 4.0358 5.7068 3.7971 9.2546
RL95-2 GDSC1; GDSC2; CTRP2 4.5356 5.5128 4.4049 5.6022
JHUEM-2 CTRP2; CTRP1 4.6284 5.2262 4.5348 3.2034
JHUEM-1 CTRP2 4.7168 7.0288 3.1025 3.2809
HEC-1-A CTRP2 4.7428 5.5626 4.5051 2.9253
HEC-6 CTRP2 4.9054 7.6054 2.9546 3.6265
JHUEM-3 CTRP2 4.9587 8.0562 2.7739 4.3248
EFE-184 CTRP2 5.1084 6.305 4.4667 2.3076
HEC-151 CTRP2; CTRP1 5.1888 6.511 4.4381 2.367
HEC-50B CTRP2 5.2046 6.9479 1.5128 0.1257
MFE-296 GDSC1; GDSC2; CTRP2 5.2141 6.5111 4.6352 3.0453
MFE-280 GDSC1; GDSC2 5.3456 9.1027 3.4512 9.0442
HEC-108 CTRP2; CTRP1 5.7673 10.3392 2.9833 7.4345
MFE-319 GDSC1; GDSC2; CTRP2 5.7903 7.0453 4.8123 1.3634
JHUEM-7 CTRP2 6.2181 7.9075 3.5308 0.3322
HEC-265 CTRP2 6.3202 7.3167 4.7166 0.1761
HEC-251 CTRP2 6.4872 12.021 1.8977 5.8194
HEC-59 CTRP2; CTRP1 6.5709 9.6018 3.8896 2.6468
AN3-CA GDSC1; GDSC2; CTRP2 7.3093 9.4875 4.5702 0.8195
HEC-1-B CTRP2 8.5773 19.8744 -0.4513 11.787
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 4.0958 5.1216 3.9901 6.7817
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMRC-2 CTRP2 1.5088 7.5871 -0.0979 24.5757
NCC010 GDSC1 2.5163 4.2927 2.3593 23.5945
KMRC-3 CTRP2 2.6123 3.2961 2.6121 16.2035
786-O GDSC1; GDSC2; CTRP2 2.774 3.7548 2.771 16.6764
BFTC-909 GDSC1; GDSC2; CTRP2 2.8535 3.983 2.8451 16.1743
TUHR10TKB CTRP2 3.1789 4.7115 2.3263 3.2524
RXF 393L GDSC1 3.2561 4.3601 3.2399 23.0443
TUHR4TKB CTRP2 3.5329 4.2246 3.5278 10.0868
UO-31 GDSC1; CTRP2 3.7037 4.3347 3.7016 10.592
769-P GDSC1; GDSC2; CTRP2 3.8028 4.5852 3.793 9.9692
OS-RC-2 GDSC1; GDSC2; CTRP2 4.1085 4.8627 4.0891 8.0015
Caki-2 CTRP2 4.2182 10.0322 1.2233 12.5034
RCC10RGB GDSC1; GDSC2; CTRP2; CTRP1 4.2442 4.9641 4.2207 7.128
A-704 GDSC1; GDSC2 4.3405 9.1327 1.932 12.483
KTCTL-21 GDSC1 4.3769 6.206 3.9637 13.0773
KTCTL-1M GDSC1 4.5497 5.6294 4.3789 9.6115
ACHN GDSC1; GDSC2; CTRP2 4.5713 5.3377 4.4984 5.161
LB1047-RCC GDSC1 4.6956 6.3531 4.2227 9.9916
KTCTL-195 GDSC1; GDSC2 4.706 5.5618 4.5718 5.3129
BB65-RCC GDSC1 4.861 5.5499 4.7424 5.8426
NCC021 GDSC1 4.8958 10.71 2.265 21.7133
KTCTL-140 GDSC1 4.9132 5.7833 4.7002 5.8818
KTCTL-26A GDSC1 5.0163 5.8117 4.7917 4.8339
KMRC-1 GDSC1; GDSC2; CTRP2 5.0553 6.3558 4.5688 3.6532
SNU-1272 CTRP2 5.1997 6.8027 4.291 2.8794
VMRC-RCZ GDSC1; GDSC2; CTRP2 5.2323 7.4283 4.1932 4.8311
SW156 GDSC1 5.7137 8.3188 4.1362 7.129
VMRC-RCW GDSC1; CTRP2 5.8373 9.4684 3.661 5.9373
A-498 GDSC1; GDSC2; CTRP2 5.998 8.7468 4.135 3.7563
SW13 GDSC1; GDSC2 6.5055 9.1106 4.2996 2.8689
Caki-1 GDSC1; CTRP2 6.7881 12.7719 2.7369 8.1523
LB2241-RCC GDSC1 6.9121 9.0814 4.5436 1.9976
TK-10 GDSC1; GDSC2 7.0278 11.2753 3.6185 5.1552
KMRC-20 GDSC1; GDSC2; CTRP2 7.1585 8.944 4.7173 0.5276
SN12C GDSC1; GDSC2 7.3335 9.5415 4.5597 0.9821
KTCTL-13 GDSC1 7.4918 9.9127 4.4839 1.5985
CAL-54 GDSC1; GDSC2; CTRP2 7.5293 12.8993 3.1769 5.4269
LB996-RCC GDSC1; GDSC2 7.7543 9.9834 4.5736 0.6811
HA7-RCC GDSC1 7.845 9.9992 4.6057 0.8007
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 61 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CL-34 CTRP1 2.3105 4.5567 2.1801 39.9973
OUMS-23 CTRP2 3.0038 4.8654 2.8636 14.081
HT115 GDSC1; CTRP2; CTRP1 3.0374 3.7135 3.0371 14.9446
COLO201 CTRP2 3.3889 5.3683 2.8007 7.3992
RKO GDSC1; GDSC2; CTRP2; CTRP1 3.3925 5.0564 3.2823 12.9943
COLO205 GDSC1; GDSC2; CTRP2 3.4221 4.3464 3.413 12.4568
HT-29 GDSC1; GDSC2; CTRP2; CTRP1 3.4228 5.2524 3.268 12.9524
CL-40 CTRP1 3.4615 4.2268 3.4544 22.8707
SNU-175 GDSC1; GDSC2; CTRP1 3.4776 6.1824 3.0227 16.1395
LS411N GDSC1; GDSC2; CTRP2 3.4942 5.4981 3.2765 12.7098
KM12 GDSC1; GDSC2; CTRP2; CTRP1 3.5627 6.3746 3.0388 13.3946
LS513 GDSC1; GDSC2; CTRP2 3.5839 4.85 3.5301 11.5489
NCI-H747 GDSC1; GDSC2; CTRP2 3.5906 5.1237 3.4827 11.6916
SNU-C2B GDSC1; GDSC2 3.6249 5.2047 3.5006 13.5895
HCC2998 GDSC1; GDSC2 3.658 4.5779 3.6426 12.8939
SNU-1033 CTRP2 3.6784 5.4765 3.4167 10.0416
MDST8 GDSC1; GDSC2; CTRP2; CTRP1 3.6814 4.3705 3.678 10.7422
NCI-H716 GDSC1; GDSC2; CTRP2 3.7294 4.6534 3.7107 10.4788
SNU-C2A CTRP2 3.8146 8.5953 0.1219 6.6672
COLO 678 GDSC1; GDSC2; CTRP2; CTRP1 3.8516 5.2309 3.7413 9.9943
LS1034 GDSC1; GDSC2; CTRP2 3.8782 5.3779 3.7307 9.9523
T84 GDSC1; GDSC2; CTRP2 3.9723 5.4719 3.8055 9.4068
SW48 GDSC1; GDSC2; CTRP2 3.9865 6.4287 3.463 10.6473
SK-CO-1 GDSC1; GDSC2; CTRP2 4.1033 5.6722 3.4569 4.2876
SNU-81 GDSC1; CTRP1 4.132 5.3871 4.005 13.9659
SNU-1040 GDSC1; CTRP1 4.3105 5.2845 4.2281 11.7173
CCK-81 GDSC1; GDSC2; CTRP2 4.3385 5.8526 4.0684 7.4023
SW626 GDSC1; GDSC2 4.3547 5.9646 4.0411 8.7979
COLO 320HSR GDSC1; GDSC2 4.3915 6.0261 4.0547 8.6213
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2; CTRP1 4.607 5.3264 4.5405 4.905
HCT 15 GDSC1; GDSC2; CTRP2 4.6109 6.985 3.8429 7.6002
NCI-H508 GDSC1; CTRP2; CTRP1 4.6933 8.5169 3.0165 9.3062
GP5d GDSC1; GDSC2 4.7968 6.1024 4.4389 5.6355
SNU-61 GDSC1; GDSC2; CTRP2; CTRP1 4.82 6.615 4.2209 5.594
HT-55 GDSC1; GDSC2; CTRP2; CTRP1 4.8759 6.2891 4.4302 4.6232
SNU-C1 GDSC1; GDSC2; CTRP2 4.8869 7.8891 3.6599 7.7305
SNU-C4 CTRP2; CTRP1 4.916 10.9322 2.0023 13.0342
SNU-C5 GDSC1; GDSC2; CTRP2; CTRP1 5.0295 7.0772 4.1901 5.2567
SW1417 GDSC1; GDSC2; CTRP2 5.0814 7.7313 3.9114 6.294
SW837 GDSC1; GDSC2 5.0823 6.3481 4.5976 4.0994
CW-2 GDSC1; GDSC2; CTRP2; CTRP1 5.0826 6.4818 4.5322 3.7431
SW948 GDSC1; GDSC2; CTRP2; CTRP1 5.099 6.3502 4.6119 3.3819
LS180 GDSC1; GDSC2; CTRP2; CTRP1 5.2437 6.9293 4.4522 3.7405
LoVo GDSC1; GDSC2; CTRP2; CTRP1 5.2706 8.0493 3.9153 5.9033
SNU-407 GDSC1; GDSC2; CTRP2 5.2935 8.1197 3.8993 5.9254
HCT 116 GDSC1; GDSC2; CTRP2; CTRP1 5.3084 7.6257 4.1588 4.8261
DLD-1 CTRP2 5.415 6.4515 3.7466 0.1954
CaR-1 GDSC1; GDSC2 5.4244 6.6923 4.7202 2.7072
C2BBe1 GDSC1; GDSC2; CTRP2 5.6485 9.2919 3.6021 6.5015
COLO 320 CTRP2; CTRP1 5.8763 8.3449 4.0371 2.9469
LS123 GDSC1; GDSC2; CTRP2; CTRP1 6.2276 9.0434 4.1511 3.3612
SW1116 GDSC1; GDSC2 6.3645 9.962 3.8028 5.36
GP2d CTRP2 6.4313 7.769 3.659 0.0912
HCC-56 CTRP2 6.644 7.9117 4.6267 0.233
DiFi GDSC1; GDSC2 6.6942 9.0597 3.5178 0.9423
HCT 8 CTRP2; CTRP1 6.71 7.8327 4.6947 0.1317
SW620 GDSC1; GDSC2; CTRP2; CTRP1 6.8641 8.6219 4.7112 0.7109
SW480 CTRP1 7.0036 9.1013 4.3368 1.6709
SNU-503 CTRP2 7.1961 9.1668 4.3829 0.5194
SW1463 GDSC1; GDSC2 7.3421 9.3797 4.6281 0.7672
CL-11 GDSC1; GDSC2; CTRP2 7.9316 9.7686 4.7242 0.236
⏷ Show the Full List of 61 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 2.7323 3.9845 2.7203 20.0203
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-6 CTRP2 1.0643 2.6708 1.058 26.5371
HLF CTRP2 2.0828 3.8246 2.0459 19.855
SNU-182 CTRP2 2.1159 4.0725 2.0518 19.7275
Hep-G2 CTRP2; CTRP1 2.4584 3.2018 2.4581 17.3092
SNU-423 GDSC1; GDSC2; CTRP2 2.5984 3.4928 2.5973 17.8188
SNU-475 GDSC1; CTRP2 2.8324 3.763 2.8301 16.292
SNU-387 GDSC1; CTRP2 2.9833 4.3357 2.9563 15.3866
SNU-761 CTRP2 3.3492 8.7574 -0.2765 9.4535
SNU-398 GDSC1; GDSC2; CTRP2; CTRP1 3.5767 4.6101 3.5542 11.4905
JHH-1 GDSC1; GDSC2; CTRP2 3.5926 5.1778 3.472 11.7229
JHH-6 GDSC1; GDSC2; CTRP2; CTRP1 3.8448 4.4768 3.8415 9.6731
HLE GDSC1; GDSC2 4.1384 5.1687 4.0687 9.4076
Huh-7 GDSC1; GDSC2 4.2471 5.1376 4.1936 8.5035
JHH-5 CTRP2 4.4774 8.7122 2.0915 8.1814
SK-HEP-1 GDSC1; GDSC2; CTRP2 4.4873 4.9584 4.4787 5.4877
JHH-7 GDSC1; GDSC2 4.7298 5.4155 4.6479 4.9035
Li-7 CTRP2 4.7522 7.0904 3.0974 3.2474
SNU-878 CTRP2 5.1557 7.4837 3.9162 4.5317
SNU-449 GDSC1; GDSC2; CTRP2; CTRP1 5.2818 6.1201 4.8889 1.8644
JHH-2 GDSC1; GDSC2; CTRP2 5.3851 7.2712 4.3995 3.689
Hep 3B2.1-7 GDSC1; CTRP2 5.6391 9.1124 3.6841 6.1814
SNU-886 CTRP2 6.4205 8.1506 3.5216 0.2822
HuH-1 GDSC1; GDSC2; CTRP2 7.144 8.6275 4.8316 0.2875
Hep-G2/C3A GDSC1; GDSC2 7.5079 8.9826 4.8439 0.1956
PLC/PRF/5 CTRP2 7.5301 14.2088 2.3313 7.3401
JHH-4 GDSC1; GDSC2; CTRP2 7.7884 11.8189 3.8257 2.7786
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 223 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCLC-21H CTRP1 -0.2273 0.5063 -0.2273 75.4886
IST-SL1 GDSC1 1.5185 2.4178 1.5184 42.261
NCI-H810 GDSC1; GDSC2; CTRP2 1.5973 2.6809 1.5968 24.3654
COR-L51 CTRP1 1.8376 5.5594 1.395 46.9163
NCI-H1435 GDSC1; CTRP2; CTRP1 1.9499 2.7502 1.9498 22.0575
Lu-139 GDSC1; GDSC2 2.028 3.1133 2.0267 25.4114
NCI-H211 GDSC1; GDSC2; CTRP2 2.1232 3.5413 2.1141 20.9534
NCI-H748 GDSC1 2.1438 5.1712 1.8935 40.8489
COR-L303 GDSC1 2.2227 3.4471 2.2184 38.7666
NCI-H64 GDSC1; GDSC2 2.293 3.5179 2.2881 23.3812
NCI-H1105 GDSC1; CTRP2; CTRP1 2.3568 4.1692 2.2967 18.1879
NCI-H1666 GDSC1; GDSC2; CTRP2 2.3817 4.4124 2.308 19.4783
SBC-1 GDSC1 2.4051 3.9991 2.3795 32.5511
Lu-135 GDSC1; GDSC2 2.4364 3.8513 2.422 22.3123
NCI-H2731 GDSC1; GDSC2 2.5112 4.4112 2.4466 21.9332
NCI-H1688 GDSC1; GDSC2 2.5233 3.4201 2.5224 21.5894
COR-L95 GDSC1; GDSC2; CTRP2 2.633 4.382 2.5804 17.7637
CPC-N GDSC1; GDSC2 2.6373 4.6295 2.548 21.0595
NCI-H1436 GDSC1 2.6512 6.1661 2.1399 32.4046
Ms-1 GDSC1; GDSC2 2.6535 3.865 2.6448 20.6153
DMS 114 GDSC1; GDSC2; CTRP2 2.69 3.4923 2.6894 17.2178
NCI-H446 GDSC1; GDSC2; CTRP2 2.7632 3.9859 2.7521 16.7738
NCI-H520 GDSC1; GDSC2; CTRP2 2.7993 4.2931 2.7668 16.6083
NCI-H187 GDSC1 2.7997 4.6038 2.727 28.4342
LC-2/ad GDSC1 2.8057 3.696 2.8041 27.9668
SK-MES-1 GDSC1; GDSC2; CTRP2 2.8293 4.124 2.8124 16.3604
NCI-H1963 GDSC1; GDSC2; CTRP1 2.8491 5.5714 2.5513 20.2884
NCI-H2087 GDSC1; GDSC2; CTRP2 2.8588 4.7217 2.7707 16.4074
LCLC-97TM1 GDSC1; GDSC2; CTRP2 2.8624 4.2972 2.8329 16.186
NCI-H1341 GDSC1; GDSC2; CTRP2 2.9068 4.62 2.687 10.7278
COR-L321 GDSC1 2.9232 4.1041 2.911 26.7204
COR-L311 GDSC2 2.9367 14.6766 -3.3509 27.2354
DV-90 CTRP2 2.9561 5.7782 2.1807 11.2192
SW1271 GDSC1; GDSC2; CTRP2 2.9698 4.9768 2.8403 15.824
COLO 668 GDSC1; GDSC2; CTRP2; CTRP1 3.007 4.3964 2.9753 15.2474
COR-L279 GDSC1; GDSC2; CTRP2 3.0112 5.5604 2.4328 11.4475
NCI-H1734 GDSC1; CTRP2 3.0149 4.046 3.0081 15.1129
EBC-1 GDSC1; GDSC2; CTRP2 3.0416 4.8978 2.935 15.2758
HOP-62 GDSC1; GDSC2; CTRP2 3.0566 4.1408 3.0467 14.8504
NCI-H889 CTRP2 3.1214 4.5011 2.8971 7.7431
NCI-H1836 GDSC1; CTRP1 3.1235 4.3307 3.1037 24.5379
COR-L88 GDSC1; GDSC2; CTRP2 3.1559 4.6772 3.0978 14.3626
NCI-H292 GDSC1; CTRP2 3.2061 4.7756 3.1358 14.0753
NCI-H290 GDSC1 3.2064 4.1735 3.1416 14.3636
EPLC-272H GDSC1; GDSC2; CTRP2 3.2086 4.5187 3.1752 13.9345
NCI-H2795 GDSC1; GDSC2 3.2245 4.2895 3.2119 16.2265
NCI-H2810 GDSC1 3.2388 4.5153 3.082 14.585
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2 3.2598 4.5805 3.2221 13.614
HCC1833 CTRP2; CTRP1 3.2677 5.0642 3.1027 12.4986
DMS 454 CTRP2 3.2788 4.782 3.1824 12.0951
NCI-H146 GDSC1 3.2861 4.1598 3.2313 13.3023
HCC33 GDSC1 3.3066 4.3804 3.291 25.2901
NCI-H1184 CTRP2 3.3106 5.2049 3.1061 12.2726
NCI-H196 GDSC1; GDSC2; CTRP2 3.316 4.0501 3.3144 13.1264
NCI-H1693 GDSC1; GDSC2; CTRP2 3.3165 4.898 3.2328 13.3997
PC-14 GDSC1; GDSC2; CTRP2 3.3244 4.3947 3.3085 13.1189
NCI-H835 GDSC1; GDSC2 3.334 4.4227 3.2146 8.7855
Lu-134-A GDSC1 3.3684 4.8038 3.3058 22.0614
LB647-SCLC GDSC1 3.3691 4.6304 3.3321 21.9071
CAL-12T GDSC1; CTRP2; CTRP1 3.3929 4.9346 3.3085 12.9025
LK-2 GDSC1; GDSC2 3.4226 4.6033 3.3921 14.7687
COR-L32 GDSC1 3.4412 4.571 3.2828 12.075
NCI-H2106 CTRP2 3.4645 4.6807 3.1877 5.5395
VMRC-LCD GDSC1; GDSC2; CTRP2 3.4818 5.6759 2.8609 8.3851
NCI-H226 GDSC1; GDSC2; CTRP2 3.4878 4.3511 3.4805 12.0216
NCI-H2029 GDSC1; CTRP2 3.5078 5.0365 3.4121 12.1904
EMC-BAC-1 GDSC1 3.521 5.4539 3.3189 21.1947
LXF 289 GDSC1; GDSC2; CTRP2; CTRP1 3.5736 4.5649 3.5553 11.4965
NCI-H2081 GDSC1; CTRP2; CTRP1 3.5752 4.6134 3.5523 11.5015
NCI-H2227 GDSC1 3.5869 4.4428 3.5779 19.3286
NCI-H2347 GDSC1; GDSC2 3.5895 8.3759 2.1879 19.5257
UMC-11 GDSC1; GDSC2 3.5988 4.9284 3.5324 13.5536
SK-LU-1 GDSC1; CTRP2; CTRP1 3.6166 4.4332 3.6091 11.1793
NCI-H510A GDSC1 3.6289 4.9303 3.5646 21.5757
NCI-H727 GDSC1; GDSC2; CTRP2 3.6402 4.8077 3.5971 11.1445
NCI-H661 GDSC1; GDSC2; CTRP2 3.6407 4.563 3.6257 11.0466
COLO 699 CTRP2; CTRP1 3.6556 4.2846 3.6513 9.3543
BEN GDSC1; CTRP2 3.674 4.7172 3.6453 10.8746
HCC78 GDSC1; GDSC2; CTRP2 3.6765 4.7445 3.6447 10.8688
RERF-LC-Sq1 GDSC1; GDSC2 3.6788 5.8495 3.3613 13.9962
NCI-H1915 GDSC1; GDSC2; CTRP2; CTRP1 3.6994 5.3253 3.5503 11.1252
COR-L105 GDSC1; GDSC2; CTRP2 3.7159 5.9819 3.3533 11.7951
DMS 273 GDSC1; GDSC2; CTRP2 3.7367 4.3889 3.7339 10.3783
HCC15 GDSC1; GDSC2; CTRP2; CTRP1 3.7436 5.006 3.6743 10.5574
SBC-3 GDSC1; GDSC2 3.755 5.6947 3.4973 13.1516
NCI-H1694 GDSC1; GDSC2; CTRP2; CTRP1 3.7569 5.3267 3.6127 10.7328
Lu-99A GDSC1; GDSC2 3.784 5.0235 3.7146 12.1379
Sq-1 CTRP2; CTRP1 3.785 5.3919 3.5653 9.2646
COR-L23 GDSC1; GDSC2; CTRP1 3.7986 4.5152 3.7926 11.7728
LC-1/sq GDSC1; GDSC2 3.8007 4.8852 3.7574 11.9043
NCI-H2591 GDSC1; GDSC2 3.8193 4.7219 3.7987 11.6703
NCI-H526 GDSC1; GDSC2; CTRP2 3.845 4.8555 3.8093 9.7798
NCI-H2595 GDSC1; GDSC2 3.8503 5.7567 3.5792 12.4773
HCC44 GDSC1; GDSC2; CTRP2 3.8683 7.2329 2.9905 12.7843
NCI-H2461 GDSC1; GDSC2 3.869 5.439 3.7028 11.8846
NCI-H647 GDSC1; CTRP2 3.9025 5.4416 3.7386 9.8522
HCC1359 CTRP1 3.9088 4.5105 3.9007 16.4879
NCI-H3122 GDSC1; GDSC2 3.9363 5.6627 3.7047 11.6463
NCI-H847 GDSC1; GDSC2 3.9406 5.1309 3.862 10.9681
NCI-H1975 GDSC1; GDSC2 3.9427 4.9246 3.9037 10.7916
LK2 CTRP2 3.9722 4.4258 3.8147 1.4849
NCI-H2804 GDSC1 3.9837 5.0788 3.92 15.2344
NCI-H82 GDSC1; GDSC2 3.991 6.2144 3.5562 12.1212
NCI-H1437 GDSC1 4.0153 5.8794 3.7126 16.3478
NCI-H2369 GDSC1; GDSC2 4.0157 4.6065 4.0115 10.0912
NCI-H2722 GDSC1; GDSC2 4.0226 5.2031 3.9345 10.3757
HCC2935 CTRP2; CTRP1 4.0234 5.0933 3.9193 7.2568
Lu-165 GDSC1; GDSC2 4.0378 4.6553 4.032 9.9268
RERF-LC-KJ GDSC1; GDSC2; CTRP1 4.041 5.0787 3.9821 10.1138
NCI-H524 GDSC1; GDSC2 4.0442 5.1813 3.9632 10.1796
NCI-H1944 GDSC1; GDSC2; CTRP2 4.0452 5.2152 3.9562 8.6544
NCI-H2196 GDSC1; CTRP2 4.05 6.0609 3.68 9.6515
NCI-H596 GDSC1; GDSC2; CTRP1 4.0513 4.9253 4.0199 9.9241
NCI-H1563 GDSC1; GDSC2; CTRP2 4.0719 5.6161 3.8674 8.894
NCI-H2228 GDSC1; GDSC2; CTRP2 4.0753 5.5286 3.8998 8.7664
NCI-H1299 GDSC1; GDSC2; CTRP2 4.1007 4.96 4.0677 8.0986
NCI-H1876 GDSC1; GDSC2; CTRP1 4.1476 4.9858 4.114 9.1902
HCC366 GDSC1; CTRP2 4.1542 5.0703 3.8002 2.6682
EMC-BAC-2 GDSC1; GDSC2 4.2008 5.1436 4.142 8.8818
NCI-H522 GDSC1; GDSC2; CTRP2 4.2222 5.7713 3.9748 8.0733
NCI-H2110 GDSC1; CTRP2; CTRP1 4.2514 6.6238 3.6521 9.2314
SHP-77 GDSC1; GDSC2; CTRP2 4.2587 5.0396 4.2246 7.069
NCI-H1092 GDSC1; GDSC2; CTRP2 4.2617 6.6543 3.649 9.2174
LUDLU-1 CTRP2 4.2703 5.6161 3.9959 6.1725
NCI-H2869 GDSC1 4.2732 5.8982 3.9811 13.4343
A-549 GDSC1; GDSC2; CTRP2 4.2853 6.0851 3.9188 8.1124
LCLC-103H GDSC1; GDSC2; CTRP2 4.2892 5.0791 4.2507 6.8847
DMS 79 GDSC1 4.2909 5.6995 4.075 12.7561
LOU-NH91 GDSC1; GDSC2; CTRP2 4.2991 5.2485 4.2249 6.9436
NCI-H358 GDSC1; GDSC2; CTRP2 4.3198 5.3832 4.211 6.9308
NCI-H322M GDSC1; GDSC2 4.3698 5.4338 4.2503 7.8329
NCI-H69 GDSC1; GDSC2; CTRP2 4.4039 10.9949 1.6883 16.6694
T3M-10 CTRP2; CTRP1 4.4373 5.0761 4.3758 4.3524
SBC-5 GDSC1; GDSC2; CTRP2 4.4422 5.3272 4.3604 6.0356
HCC4006 CTRP1 4.4428 5.5874 4.1938 10.7901
NCI-H3255 GDSC1; CTRP1 4.4682 5.18 4.4248 9.7346
NCI-H2171 GDSC1; CTRP2 4.4692 6.3795 3.9826 7.389
NCI-H2141 GDSC1; GDSC2; CTRP2; CTRP1 4.5295 6.9995 3.7569 8.1362
HCC1195 CTRP2; CTRP1 4.5305 5.1095 4.4677 3.738
HCC95 CTRP2 4.537 5.9523 4.1203 4.989
NCI-H1755 GDSC1; GDSC2; CTRP2; CTRP1 4.5383 5.3643 4.4548 5.4139
HOP-92 GDSC1; GDSC2; CTRP2 4.5465 6.4647 4.0223 7.0401
NCI-H2135 GDSC1 4.5763 5.7965 4.3429 9.7169
HCC1171 CTRP2 4.5877 9.632 2.3596 12.1717
NCI-H2085 GDSC1; GDSC2; CTRP2 4.5891 5.9637 4.2873 5.8984
NCI-H2023 GDSC1; GDSC2; CTRP2; CTRP1 4.5909 6.1766 4.1968 6.2445
NCI-H841 GDSC1; GDSC2; CTRP2; CTRP1 4.6056 5.2929 4.5479 4.8833
NCI-H1581 GDSC1; GDSC2; CTRP2 4.609 5.3601 4.5332 4.925
NCI-H1792 GDSC1; GDSC2; CTRP2 4.6117 7.9223 3.391 9.4248
NCI-H2122 GDSC1; GDSC2; CTRP2; CTRP1 4.6149 6.185 4.2176 6.1025
NCI-H2073 CTRP1 4.6356 5.109 4.5823 6.4507
NCI-H1355 GDSC1; GDSC2; CTRP2 4.6678 6.9591 3.91 7.198
NCI-H2030 GDSC1; CTRP2; CTRP1 4.6752 5.2185 4.6414 4.3449
NCI-H650 GDSC1; GDSC2; CTRP2 4.6904 5.8646 4.4348 5.066
NCI-H2803 GDSC1 4.7015 6.0637 4.3598 9.05
NCI-H2009 GDSC1; GDSC2; CTRP2; CTRP1 4.72 6.1844 4.3244 5.4206
NCI-H1648 GDSC1; GDSC2 4.7223 5.8811 4.4609 5.7566
NCI-H1568 GDSC1; GDSC2; CTRP2 4.7285 8.5507 3.1898 9.99
ChaGo-K-1 GDSC1; CTRP2 4.7368 5.975 4.4351 4.9447
MOR/CPR CTRP2 4.7553 5.6037 4.4982 2.9225
Calu-6 GDSC1; GDSC2; CTRP2 4.7561 5.8218 4.5213 4.5611
IA-LM GDSC1; GDSC2; CTRP2 4.7677 5.3811 4.6999 3.8607
NCI-H1770 GDSC1 4.7678 5.3045 4.7219 6.4237
NCI-H23 GDSC1; GDSC2; CTRP2 4.7805 10.0677 2.484 12.746
NCI-H838 GDSC1; CTRP2 4.8125 5.9263 4.5341 4.3664
NCI-H1623 GDSC1; GDSC2; CTRP2 4.8259 5.5 4.7233 3.6079
HCC1438 CTRP2 4.8386 5.4817 4.6371 2.1555
NCI-H2373 GDSC1; GDSC2 4.8685 5.4766 4.7776 3.8766
SW1573 GDSC1; GDSC2 4.8913 6.1957 4.4893 5.1292
NCI-H1838 GDSC1; GDSC2; CTRP2 4.9309 7.26 4.0105 6.2021
NCI-H345 GDSC1 4.9369 6.2354 4.5148 7.0335
RERF-LC-Ad1 CTRP2 4.9398 16.7805 -1.5635 21.3275
RERF-LC-MS GDSC1; CTRP2 4.981 5.9945 4.6717 3.4082
NCI-H1304 GDSC1 5.0111 6.1781 4.6136 6.066
NCI-H1869 GDSC1; CTRP2 5.0308 6.1252 4.6578 3.3475
NCI-H441 GDSC1; GDSC2; CTRP2; CTRP1 5.0408 6.3129 4.5763 3.6549
NCI-H2818 GDSC1; GDSC2 5.054 6.1899 4.6485 3.9295
NCI-H1793 GDSC1; GDSC2; CTRP2 5.0585 6.9194 4.2942 4.7686
A-427 GDSC1 5.0892 8.0156 3.7765 11.5864
Lu-99 CTRP2 5.0985 7.0359 3.3463 1.731
NCI-H2444 GDSC1; CTRP2 5.113 5.7484 4.9168 2.1151
NCI-H1930 CTRP1 5.1818 6.9369 4.2202 7.0637
NCI-H1781 GDSC1; GDSC2; CTRP1 5.2531 6.2216 4.8135 2.6325
HCC2279 CTRP2 5.2829 15.8998 -0.1859 20.1857
NCI-H2126 CTRP2 5.2842 8.6281 2.7203 4.0643
NCI-H2405 GDSC1; GDSC2; CTRP2 5.3171 7.2073 4.3752 3.9164
NCI-H2172 GDSC1; CTRP2; CTRP1 5.3813 7.6926 4.1857 4.5779
NCI-H2342 GDSC1; GDSC2; CTRP2; CTRP1 5.4059 7.8841 4.1102 4.8441
NCI-H2170 GDSC1; GDSC2; CTRP2 5.441 6.9995 4.5802 2.8428
NCI-H1048 GDSC1; GDSC2 5.487 6.7444 4.7431 2.4687
Calu-3 GDSC1; GDSC2; CTRP2 5.5291 8.3954 3.9543 5.2638
NCI-H2066 GDSC1; GDSC2 5.615 8.1992 3.3256 2.8256
NCI-H460 GDSC1; CTRP2; CTRP1 5.6195 7.4028 4.5179 2.7951
NCI-H1650 GDSC1; GDSC2; CTRP2 5.6592 9.4718 3.5209 6.8165
Lu-65 GDSC1; GDSC2; CTRP2 5.7861 8.1852 4.2563 3.5926
LC-1/sq-SF CTRP2 5.9397 7.1783 3.6863 0.1473
NCI-H1573 GDSC1; GDSC2; CTRP2 5.9578 8.5593 4.1977 3.5646
NCI-H1703 GDSC1; GDSC2; CTRP2 6.0842 10.7496 3.2142 7.3495
HCC827 GDSC1; GDSC2; CTRP2; CTRP1 6.2246 9.2912 4.0299 3.8451
RERF-LC-A1 CTRP2 6.2928 9.9478 3.5388 4.285
NCI-H720 GDSC1; GDSC2 6.2957 8.3158 4.5377 2.1108
NCI-H2291 GDSC1; CTRP2 6.3197 11.869 2.8381 8.4821
RERF-LC-Ad2 CTRP2 6.3363 7.8203 3.6073 0.1691
Calu-1 CTRP2 6.3919 7.7659 4.5757 0.4569
NCI-H1155 GDSC1; GDSC2; CTRP2 6.4317 8.4921 4.5383 1.6387
NCI-H1993 GDSC1; GDSC2 6.517 12.0685 2.8854 9.3673
HCC2108 CTRP2; CTRP1 6.5559 8.7813 4.2475 1.3849
NCI-H2286 CTRP2; CTRP1 6.6047 8.3658 4.4471 0.7241
NCI-H1339 CTRP2 6.9978 10.7734 3.5977 3.1849
DMS 53 GDSC1; GDSC2 7.0333 9.2141 4.5492 1.256
NCI-H1373 CTRP2 7.1131 12.7709 2.7393 6.3258
IST-SL2 GDSC1 7.1239 11.5445 3.5536 7.5508
KNS-62 GDSC1; GDSC2; CTRP2 7.1329 9.0942 4.3837 0.5471
NCI-H209 GDSC1; GDSC2 7.1951 15.8214 1.5397 13.9352
NCI-H1651 GDSC1; GDSC2; CTRP2 7.2494 9.2326 4.6445 0.6595
NCI-H513 GDSC1; GDSC2 7.3242 14.8269 2.117 11.3231
HCC1588 CTRP2 7.7301 17.7605 0.7617 12.8078
EKVX GDSC1; CTRP2 7.7917 9.748 4.6774 0.3527
PaCa-3 GDSC1; GDSC2 7.9116 13.8435 2.9773 6.6897
NCI-H1395 CTRP2 8.0735 10.5825 4.2133 0.518
ABC-1 GDSC1 8.0748 9.8923 4.7339 0.3238
NCI-H322 CTRP2 8.1665 14.36 2.6597 5.33
Hs 888.Lu CTRP2 8.2384 14.991 2.4137 6.1458
⏷ Show the Full List of 223 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 2.45 4.502 2.3676 22.476
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 2.2215 3.7067 2.201 18.8752
Yamato-SS CTRP2 2.7159 3.207 2.7159 15.5125
TE 441.T CTRP2 0.4463 1.3968 0.4463 30.6329
TE 617.T CTRP2 1.3837 2.238 1.383 19.2418
Hs 729.T CTRP2 1.4593 1.9713 1.4593 18.7013
Rh18 GDSC1; CTRP2 1.7406 2.4095 1.7406 22.0102
Tm87-16 CTRP2 2.5344 3.0903 2.5344 16.7217
BT-12 CTRP2 2.6187 2.9331 2.6187 16.16
Rh41 GDSC1; GDSC2; CTRP2 2.6834 3.536 2.6826 17.2618
BT-16 CTRP2 2.861 3.9367 2.8498 14.5836
TTC-709 CTRP2 2.9445 5.1408 2.7257 14.7584
STS-0421 GDSC1 2.9949 4.5753 2.7974 17.9061
G-402 GDSC1; GDSC2; CTRP2 3.0004 5.2819 2.7993 15.8751
EW-8 GDSC1; GDSC2 3.2868 4.6081 3.2474 15.8514
A-204 GDSC1; GDSC2; CTRP2 3.4669 4.9234 3.3907 12.3904
SW982 GDSC1; GDSC2; CTRP2 3.8129 4.7805 3.7851 9.9633
Rh30 GDSC1; GDSC2 3.9768 5.2902 3.8624 10.8372
GCT GDSC1; GDSC2; CTRP2 4.2782 5.0504 4.2439 6.9421
RKN GDSC1; GDSC2; CTRP2; CTRP1 4.3271 4.8473 4.3201 6.5305
KYM-1 GDSC1; GDSC2; CTRP2 4.3792 5.11 4.3423 6.2908
G-401 GDSC1; GDSC2; CTRP2 4.428 5.9764 4.1134 6.9901
Hs 633.T GDSC1; GDSC2 4.6109 5.2527 4.5637 5.6735
RD GDSC1; GDSC2; CTRP2 4.6277 5.855 4.3732 5.4672
SW872 GDSC1; GDSC2 4.7868 5.4426 4.701 4.4819
MFH-ino GDSC1; GDSC2 4.9303 5.7862 4.7164 3.9573
VA-ES-BJ GDSC1; GDSC2 5.2626 6.1624 4.8513 2.4265
SW684 GDSC1; GDSC2 6.0282 7.5065 4.7471 1.5575
SK-LMS-1 GDSC1; GDSC2; CTRP2 6.1497 9.9619 3.6504 5.4782
MES-SA GDSC1; GDSC2; CTRP2 6.6445 7.9017 4.8977 0.3536
HT-1080 GDSC1; GDSC2; CTRP2; CTRP1 7.0316 10.7986 3.8433 3.5211
SK-UT-1 GDSC1; GDSC2; CTRP2 7.8891 9.7973 4.6976 0.2882
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 2.4327 3.0424 2.4327 17.3994
P-STS CTRP2 5.053 8.3657 2.6898 4.5412
H-STS CTRP2 5.5344 6.4346 3.7975 0.0841
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 2.504 3.9576 2.4761 17.0185
COV434 CTRP2; CTRP1 1.5935 2.7085 1.5924 23.0681
ES-2 GDSC1; GDSC2 2.4616 3.3725 2.4607 22.0653
COV644 CTRP2; CTRP1 2.4793 3.9328 2.453 17.2574
JHOS-4 CTRP1 2.8127 3.7803 2.8073 32.1249
OVCAR-8 GDSC1; GDSC2; CTRP2; CTRP1 3.2002 4.1547 3.1936 13.9004
Caov-3 GDSC1; CTRP2; CTRP1 3.7616 4.2917 3.7608 10.2092
A2780 GDSC1; GDSC2; CTRP2; CTRP1 3.7895 4.9026 3.7426 10.1809
COV318 CTRP1 3.7932 4.3891 3.7881 18.1164
SNU-8 CTRP2 3.8481 4.9245 3.7696 8.2418
OVISE GDSC1; GDSC2; CTRP2 3.9315 4.6069 3.9249 9.1166
OVK18 GDSC1; CTRP2; CTRP1 3.9494 4.7292 3.9348 9.0264
TYK-nu GDSC1; GDSC2; CTRP2; CTRP1 3.9908 4.9541 3.9506 8.8415
COV362 CTRP2; CTRP1 3.9934 6.0995 3.5087 8.9065
OVCAR-4 GDSC1; GDSC2; CTRP2; CTRP1 4.0145 7.1417 3.1794 11.678
RMG-I GDSC1; GDSC2; CTRP2; CTRP1 4.0152 5.2834 3.9062 8.9208
OAW28 GDSC1; GDSC2; CTRP2 4.1016 5.1877 4.0243 8.2452
OV7 CTRP2; CTRP1 4.1138 5.2826 3.9587 6.8439
OVCAR-5 GDSC1; GDSC2; CTRP2 4.1308 5.0944 4.0763 7.9752
RMUG-S CTRP1 4.2021 5.6969 3.8963 14.6662
DOV13 GDSC1; GDSC2; CTRP2 4.2793 5.5196 4.1246 7.3606
SNU-119 CTRP2 4.2956 8.4436 2.6865 11.4513
OC 314 GDSC1; GDSC2; CTRP2 4.301 5.2421 4.2286 6.9249
OVMANA CTRP1 4.3546 4.9368 4.3198 10.3171
ONCO-DG-1 CTRP2 4.4448 5.9121 3.4531 2.1906
OVTOKO GDSC1; GDSC2; CTRP2 4.4794 5.2582 4.4191 5.7168
ES2 CTRP2 4.5556 5.7938 2.6433 0.2909
Kuramochi GDSC1; GDSC2; CTRP2 4.5796 5.9753 4.2725 5.9802
EFO-21 GDSC1; GDSC2; CTRP2 4.5808 6.1286 4.2076 6.2281
OV56 GDSC1; GDSC2; CTRP2 4.6036 5.3163 4.5396 4.9184
OV-90 GDSC1; GDSC2; CTRP2; CTRP1 4.6793 5.7054 4.4884 4.8915
OAW42 GDSC1; GDSC2; CTRP2; CTRP1 4.702 5.1154 4.6886 4.0997
SK-OV-3 GDSC1; GDSC2; CTRP2 4.91 5.7573 4.7083 3.4393
OVSAHO CTRP2 5.0459 7.1281 3.2723 2.0917
TOV-112D GDSC1; GDSC2; CTRP2 5.0579 6.0741 4.7082 3.082
JHOM-1 CTRP2; CTRP1 5.1528 6.4657 4.4321 2.4565
JHOS-2 GDSC1; CTRP2 5.2254 6.9117 4.4453 3.8051
FU-OV-1 GDSC1; GDSC2; CTRP2 5.4086 8.7113 3.6989 6.5357
OVKATE GDSC1; GDSC2; CTRP1 5.4348 11.4208 2.366 13.9624
MCAS CTRP2 5.5696 8.313 3.8245 4.1988
TOV-21G GDSC1; GDSC2; CTRP2 5.8407 7.8359 4.4666 2.6596
SNU-840 CTRP2; CTRP1 5.9062 10.61 2.9539 7.3254
EFO-27 GDSC1; CTRP2; CTRP1 5.9803 9.452 3.7766 5.233
IGROV-1 GDSC1; GDSC2; CTRP2; CTRP1 6.8036 10.7618 3.7155 4.2903
Caov-4 GDSC1; GDSC2 7.1701 10.0112 3.3561 1.1325
OVCAR-3 GDSC1; GDSC2 7.4792 9.1274 4.7811 0.3173
JHOC-5 CTRP2; CTRP1 8.6396 16.4028 2.0206 7.1609
HEY A8 CTRP2 8.7083 14.7844 2.7825 4.3212
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 6.1301 7.8225 3.5269 0.3735
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-Mes1 GDSC1; GDSC2; CTRP2 3.8333 5.0255 3.7676 9.9589
NCI-H28 GDSC1; GDSC2; CTRP2 3.9797 5.6469 3.757 9.5612
NCI-H2052 GDSC1; GDSC2; CTRP2 4.7343 9.7641 2.594 12.3995
NCI-H2452 GDSC1; GDSC2; CTRP2 5.6972 10.0348 3.2705 7.7771
MPP 89 GDSC1; GDSC2; CTRP2 6.1937 11.4926 2.9296 8.32
ACC-MESO-1 CTRP2 6.8436 8.3878 4.5306 0.3485
MSTO-211H GDSC1; GDSC2; CTRP2 6.881 12.5788 2.8963 7.3882
JL-1 CTRP2 10.2039 23.3448 -1.047 11.6386
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1; GDSC2; CTRP2 2.5726 5.3765 2.3064 18.8996
22Rv1 GDSC1; GDSC2; CTRP2 2.5768 4.6079 2.4865 18.259
LNCaP clone FGC GDSC1; GDSC2; CTRP2 2.7778 6.0347 2.3226 18.2426
PaCa-3 CTRP2; CTRP1 3.1338 4.1956 3.1162 12.872
PC-3 GDSC1; GDSC2 5.1168 6.8677 4.3721 5.102
DU145 GDSC1; GDSC2; CTRP2 5.5178 7.6521 4.3158 3.7958
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 5.6764 11.6976 2.2287 10.6101
A-253 GDSC1; GDSC2; CTRP2 5.8069 8.6729 4.0315 4.4742
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 4.0471 6.0902 3.6653 16.4997
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GSS CTRP2 1.7222 3.8053 1.5774 17.3655
ECC10 GDSC1; GDSC2; CTRP2 2.0661 3.2135 2.064 21.3038
OCUM-1 GDSC1; GDSC2; CTRP2 2.2799 4.0742 2.2414 20.0257
Hs 746.T GDSC1; GDSC2; CTRP2 2.3367 3.6857 2.3273 19.558
SNU-1 GDSC1; GDSC2; CTRP2 2.4368 4.1352 2.4006 18.9921
NUGC-4 GDSC1; GDSC2; CTRP2 2.9872 4.9626 2.8623 15.6945
NUGC-3 GDSC1; GDSC2; CTRP2 3.1354 4.5306 3.096 14.4335
SNU-719 CTRP2 3.1799 6.038 2.6726 14.2748
SK-GT-2 GDSC1; GDSC2 3.213 4.588 3.0299 10.089
SNU-620 CTRP2 3.328 7.2013 1.8598 11.6791
RERF-GC-1B GDSC1; GDSC2 3.3546 4.9493 3.264 15.5343
23132/87 GDSC1; GDSC2; CTRP2 3.5689 4.6543 3.5413 11.5587
GSU CTRP2 3.5749 3.8296 3.5749 9.7901
HGC-27 GDSC1; GDSC2; CTRP2 3.6275 4.8588 3.5755 11.2575
NCI-N87 GDSC1; CTRP2 3.6533 6.3849 3.1307 12.8021
IM95 GDSC1; GDSC2; CTRP2 3.7547 5.6742 3.5039 11.1303
SNU-216 CTRP2 3.8539 4.9171 3.7776 8.1957
MKN28 GDSC1; GDSC2 3.9011 6.0041 3.5434 12.4665
RF-48 GDSC1; GDSC2 3.9561 5.7591 3.6927 11.6316
TMK-1 GDSC1 4.2378 5.4386 4.105 12.8281
MKN74 CTRP2; CTRP1 4.2801 5.7129 3.9713 6.3316
AGS GDSC1; GDSC2; CTRP2; CTRP1 4.2867 5.834 4.0203 7.7248
SNU-601 CTRP2 4.3074 5.3004 4.1581 5.4483
HuG1-N CTRP2 4.341 10.6157 1.6528 15.5478
MKN1 GDSC1; GDSC2; CTRP2 4.3684 5.352 4.2729 6.5661
KATO III GDSC1; GDSC2; CTRP2 4.3998 6.3899 3.3521 4.1272
MKN7 GDSC1; CTRP2 4.5512 5.2659 4.4954 5.2317
KE-39 CTRP2 4.6696 7.1559 3.6621 6.5766
Fu97 GDSC1; GDSC2; CTRP2 4.8329 6.0884 4.4814 4.5223
MKN45 GDSC1; GDSC2; CTRP2 4.9823 6.1692 4.5902 3.7319
SNU-16 GDSC1; GDSC2; CTRP2 5.3476 8.2509 3.8788 5.9072
SCH GDSC1 5.3819 7.2371 4.4139 6.175
ECC12 CTRP2 5.7725 7.9198 4.1588 2.5294
TGBC11TKB GDSC1; GDSC2 5.9977 7.6938 4.6408 2.0739
SH-10-TC CTRP2 6.5315 7.8052 3.6814 0.0604
HSC-39 GDSC1; GDSC2 6.7058 10.6033 3.7264 5.1575
SNU-5 GDSC1; GDSC2; CTRP2 6.9796 9.9604 4.1951 2.2917
GCIY GDSC1; GDSC2 7.0259 8.8288 4.7033 0.7475
SNU-668 CTRP2 7.1086 14.887 0.9501 8.7373
LMSU CTRP2 7.635 9.1923 4.544 0.1205
SNU-685 CTRP2 6.0922 8.7552 3.1367 1.5094
SNU-1077 CTRP2 6.1568 9.557 2.8239 2.567
SNG-M GDSC1; GDSC2; CTRP2; CTRP1 6.9245 9.7254 4.2688 2.0875
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 1.4163 1.869 1.4163 19.0075
B-CPAP GDSC1; GDSC2; CTRP2 2.3392 3.2751 2.3384 19.5132
8305C GDSC1; GDSC2; CTRP2 2.5437 3.1483 2.5437 18.1731
8505C GDSC1; GDSC2; CTRP2 3.4349 4.5926 3.4064 12.4377
ML-1 [Human leukemia] GDSC1; CTRP2 3.9396 5.2898 3.822 9.445
K5 GDSC1; GDSC2 4.0435 4.769 4.03 9.9134
BHT-101 GDSC1; GDSC2; CTRP2 4.4453 5.1738 4.4012 5.8833
TT2609-C02 GDSC1; GDSC2; CTRP2 4.4497 7.0641 3.6485 8.759
IHH-4 GDSC1; GDSC2 4.9255 6.712 4.2741 6.0601
HTC-C3 GDSC1; GDSC2 5.0917 6.6338 4.4655 4.7124
CGTH-W-1 GDSC1; GDSC2; CTRP2 5.0985 6.1365 4.7162 2.9581
WRO GDSC1; GDSC2 5.1575 6.7133 4.4848 4.4567
FTC-238 CTRP2 5.2272 14.2254 -0.0658 15.7204
KMH-2 GDSC1 5.7325 7.99 4.3127 5.857
CAL-62 GDSC1; GDSC2 6.0867 9.6522 3.7564 6.0677
FTC-133 GDSC1; GDSC2; CTRP2 6.4235 8.3297 4.6066 1.405
ASH-3 GDSC1; GDSC2 6.9265 8.5365 4.7741 0.5997
TT GDSC1; GDSC2; CTRP2 7.8314 9.3374 4.8381 0.1138
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHU-029 GDSC1 2.503 4.3064 2.3411 23.7933
BHY GDSC1; CTRP2 2.6814 3.6177 2.6796 17.2782
JHU-011 GDSC1 2.7979 3.8218 2.7938 28.0676
PCI-04B GDSC1 2.9077 4.0074 2.8997 26.8696
CAL-27 GDSC1; GDSC2; CTRP2 2.9403 3.7074 2.9395 15.5814
SCC-25 GDSC1; CTRP2 3.1642 4.899 3.0677 14.4395
PCI-06A GDSC1 3.2288 4.9001 3.1375 23.7784
YD-8 CTRP2 3.3756 5.2048 2.8633 7.1642
NCI-H3118 GDSC1; GDSC2 3.463 6.0312 3.0633 16.0097
BICR 16 CTRP2 3.5482 4.6316 3.503 10.1218
SNU-899 CTRP2 3.7144 5.0357 3.2753 4.4959
YD-10B CTRP2 3.8209 6.7275 2.5392 7.5206
SCC-9 GDSC1; GDSC2; CTRP2; CTRP1 3.9073 5.0065 3.8514 9.4414
OSC-20 GDSC1; GDSC2 3.9257 5.3531 3.7896 11.3215
KOSC-2 GDSC1 3.9317 6.1825 3.5063 18.0469
PCI-38 GDSC1 4.0793 5.1648 4.0053 14.2337
SAT [Human HNSCC] GDSC1; GDSC2 4.0902 5.7545 3.8389 10.5495
SKN-3 GDSC1; GDSC2 4.1192 5.4925 3.9591 9.9338
BB30-HNC GDSC1 4.2205 5.268 4.1342 14.332
CAL-33 GDSC1; GDSC2; CTRP2 4.2337 7.0809 3.427 10.1608
HSC-3 GDSC1; GDSC2; CTRP2 4.2642 4.9284 4.2465 6.9776
UPCI-SCC-090 GDSC1; GDSC2 4.3235 6.0749 3.4468 4.611
SCC-15 GDSC1; GDSC2 4.3616 5.4158 4.2469 7.8759
HO-1-u-1 GDSC1; GDSC2 4.4313 5.4107 4.3244 7.3064
BICR 6 CTRP2 4.4485 11.2799 0.7875 13.8743
PE/CA-PJ41 (clone D2) CTRP2 4.4961 5.6107 4.2333 4.6402
SNU-1214 CTRP2 4.6183 8.9111 2.1025 7.8676
LB771-HNC GDSC1; GDSC2 4.629 6.5064 4.0855 7.7683
HO-1-N-1 GDSC1; GDSC2 4.6558 5.6472 4.486 5.8543
HSC-4 GDSC1; GDSC2; CTRP2 4.7441 7.3197 3.8084 7.4349
SNU-46 CTRP2 4.7823 7.419 2.9592 3.7998
SAS GDSC1; GDSC2 4.8086 6.32 4.3498 6.0184
OSC-19 GDSC1 5.1783 6.0663 4.8242 3.9807
PE/CA-PJ15 GDSC1; CTRP2 5.1941 11.3993 2.1761 13.1412
JHU-022 GDSC1; GDSC2 5.2107 7.4685 4.1546 5.9343
BICR 10 GDSC1; GDSC2 5.5758 7.1018 4.6337 2.8229
Ca9-22 GDSC1; GDSC2 5.5997 7.9815 4.216 4.7924
BICR 18 CTRP2 5.735 9.9922 3.1198 6.8467
BB49-HNC GDSC1 5.7919 7.6667 4.5144 4.3156
PE/CA-PJ49 CTRP2 5.8174 11.6985 1.6094 7.9722
SNU-1066 CTRP2 6.0274 7.6493 3.5496 0.3662
PE/CA-PJ34 (clone C12) CTRP2 6.0755 9.3425 3.6821 4.0151
BICR 31 GDSC1; CTRP2 6.1128 8.1414 4.5043 2.137
FaDu GDSC1; GDSC2; CTRP2 6.1964 8.3128 4.4773 2.1354
SCC-4 GDSC1; GDSC2; CTRP2 6.2355 8.1199 4.5911 1.6611
BICR 78 GDSC1; GDSC2 6.4999 9.7783 3.9824 4.3076
SNU-1076 CTRP2 6.5276 8.9365 4.1512 1.6795
HSC-2 GDSC1; GDSC2; CTRP2 6.6579 10.8092 3.596 4.9519
KON GDSC1 6.8796 9.0322 4.5477 2.0202
SNU-1041 CTRP2 6.9618 8.7508 3.5112 0.1673
BICR 56 CTRP2 6.9996 8.5941 4.5173 0.3162
Detroit 562 GDSC1; GDSC2; CTRP2 7.0095 10.1818 4.1127 2.5551
PCI-15A GDSC1 7.0202 9.0575 4.6078 1.5304
PCI-30 GDSC1; GDSC2 7.4967 9.5451 4.6315 0.6659
DOK GDSC1; GDSC2 7.5924 9.9242 4.5256 0.911
BICR 22 GDSC1; GDSC2; CTRP2 7.9608 9.2228 4.9209 0.0378
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-BLC1 CTRP2 2.7366 3.4927 2.7357 15.3778
5637 GDSC1; GDSC2; CTRP2 4.1422 6.4811 3.6026 9.7029
SW780 GDSC1; GDSC2 4.2944 5.3019 4.206 8.2828
647V GDSC1; GDSC2; CTRP2 4.3644 5.0153 4.3419 6.3383
TCCSUP GDSC1; GDSC2; CTRP2 4.3874 5.1176 4.3497 6.2398
RT-112 GDSC1; GDSC2; CTRP2 4.3982 5.3111 4.3168 6.3215
J82 GDSC1; GDSC2; CTRP2 4.42 5.4454 4.3014 6.3122
SCaBER CTRP2 4.4315 6.2259 3.2897 2.9319
RT-4 GDSC1; GDSC2; CTRP2 4.5053 9.0913 2.7199 12.3802
SW1710 GDSC1; GDSC2; CTRP2 4.5083 6.1199 4.1367 6.6897
BFTC-905 GDSC1; GDSC2; CTRP2 4.5446 5.947 4.2479 6.1668
CAL-29 GDSC1; GDSC2; CTRP2 4.5986 5.6841 4.4108 5.4039
BC-3C CTRP2 4.6959 5.3213 4.5643 2.8102
T24 GDSC1; CTRP2 4.8995 6.1311 4.5276 4.1776
JMSU-1 CTRP2 4.9631 7.8144 3.5911 6.2675
UM-UC-3 GDSC1; GDSC2; CTRP2 4.975 6.9127 4.2217 5.244
HT-1197 GDSC1; CTRP2 5.0435 9.0748 3.2087 9.2604
VM-CUB-1 CTRP2 5.3444 7.5205 3.2708 1.7456
639V GDSC1; GDSC2; CTRP2 5.7998 8.0716 4.3222 3.3039
UM-UC-1 CTRP2 6.2975 12.1507 2.4738 8.5741
KU-19-19 GDSC1; GDSC2; CTRP2 6.8583 8.8715 4.605 1.0273
HT-1376 GDSC1; GDSC2; CTRP2 6.9121 9.4284 4.3935 1.6682
KMBC-2 CTRP2 7.4548 9.3054 4.4369 0.3119
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TC-YIK GDSC1; GDSC2 2.0888 4.4839 1.8388 19.767
NEC8 GDSC1; GDSC2 2.6865 3.9028 2.6771 20.3638
NT2-D1 GDSC1; GDSC2 2.6888 3.5537 2.6879 20.3129
PA-1 GDSC1; GDSC2 2.7603 3.9543 2.7506 19.7957
KGN GDSC1; GDSC2 2.7931 4.0767 2.7779 19.5638
Ca Ski GDSC1; GDSC2 3.0881 5.017 2.9601 17.7414
SKN GDSC1; GDSC2 3.1621 4.3193 3.1449 16.7256
BPH-1 GDSC1; GDSC2 3.3876 4.8946 3.3104 15.226
HEY GDSC1; GDSC2 3.393 4.8982 3.3155 15.1851
SiSo GDSC1; GDSC2 3.4488 4.8341 3.3873 14.6903
OVMIU GDSC1; GDSC2 3.8812 6.7126 3.2328 13.9229
OVCA433 GDSC1 3.9161 4.5348 3.9123 15.6414
C-33 A GDSC1; GDSC2 4.0515 5.6857 3.8215 10.754
SW962 GDSC1 4.1986 5.3581 4.086 13.1403
CAL-39 GDSC1; GDSC2 4.2154 5.6567 4.0089 9.3935
JAR GDSC1 4.2514 6.4724 3.7189 15.2335
HT-3 GDSC1; GDSC2 4.2838 5.5226 4.1284 8.6477
MS751 GDSC1; GDSC2 4.3468 5.589 4.1745 8.2361
ACC-OV7 GDSC1 4.4048 5.4375 4.2872 10.8845
LB831-BLC GDSC1; GDSC2 4.7593 5.6819 4.5825 5.0926
OMC-1 [Human cervical carcinoma] GDSC1 4.856 5.7956 4.636 6.555
DSH1 GDSC1; GDSC2 4.8924 5.7086 4.7111 4.0964
NCC-IT GDSC1; GDSC2 4.9599 5.5048 4.8653 3.1918
SW954 GDSC1 5.0073 6.416 4.4948 7.7597
OV17R GDSC1 5.0551 6.4843 4.5057 6.6432
ME-180 GDSC1; GDSC2 5.0944 7.3299 4.1226 6.3654
DoTc2 4510 GDSC1; GDSC2 5.1116 6.3813 4.6081 3.9744
JHOS-3 GDSC1 5.138 6.8021 4.4235 6.9169
HEC-1 GDSC1; GDSC2 5.1626 6.5304 4.5802 3.9821
PEO1 GDSC1; GDSC2 5.2469 7.6191 4.1102 6.0664
UWB1.289 GDSC1 5.2746 8.258 3.8143 10.7018
HeLa GDSC1; GDSC2; CTRP2 5.3089 6.1812 4.8814 1.8429
OVCA420 GDSC1; GDSC2 5.4597 6.8346 4.6771 2.8435
SW756 GDSC1; GDSC2 5.9147 7.3325 4.7573 1.6711
SiHa GDSC1; GDSC2 6.0174 8.2737 4.3777 3.2537
C-4-I GDSC1; GDSC2 6.0749 7.8203 4.6306 2.0066
PWR-1E GDSC1; GDSC2 6.7211 8.5248 3.7311 0.3595
SKG-IIIa GDSC1; GDSC2 6.8322 8.5521 4.7245 0.8187
JEG-3 GDSC1 6.8449 8.9415 4.5684 1.9568
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7015).
2 A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nat Chem Biol. 2011 Jul 10;7(8):566-74.
3 Inhibition of euchromatic histone methyltransferase 1 and 2 sensitizes chronic myeloid leukemia cells to interferon treatment. PLoS One. 2014 Jul 31;9(7):e103915. doi: 10.1371/journal.pone.0103915. eCollection 2014.