Details of the Drug

General Information of Drug (ID: DM4RK6P)

Drug Name
AR-12
Synonyms
2-Amino-N-(4-(5-(phenanthren-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)acetamide; OSU-03012; 742112-33-0; OSU 03012; OSU03012; PDK1 inhibitor AR-12; OSU-03012 (AR-12); UNII-EX3O2Q61UV; 2-amino-N-(4-(5-(phenanthren-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)acetamide; AR 12; EX3O2Q61UV; CHEMBL1650595; 2-amino-N-[4-[5-phenanthren-2-yl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]acetamide; 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide; PubChem22592; MLS006010170; SCHEMBL570472; GTPL8005; C26H19F3N4O; EX-A253; DTXSID50225206; CHEBI:131196; MolPort-009-019-120
Indication
Disease Entry ICD 11 Status REF
Lymphoma 2A80-2A86 Phase 1 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 460.4
Logarithm of the Partition Coefficient (xlogp) 5.2
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C26H19F3N4O
IUPAC Name
2-amino-N-[4-[5-phenanthren-2-yl-3-(trifluoromethyl)pyrazol-1-yl]phenyl]acetamide
Canonical SMILES
C1=CC=C2C(=C1)C=CC3=C2C=CC(=C3)C4=CC(=NN4C5=CC=C(C=C5)NC(=O)CN)C(F)(F)F
InChI
InChI=1S/C26H19F3N4O/c27-26(28,29)24-14-23(33(32-24)20-10-8-19(9-11-20)31-25(34)15-30)18-7-12-22-17(13-18)6-5-16-3-1-2-4-21(16)22/h1-14H,15,30H2,(H,31,34)
InChIKey
YULUCECVQOCQFQ-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
10027278
ChEBI ID
CHEBI:131196
CAS Number
742112-33-0
TTD ID
D0C9JJ
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Phosphoinositide dependent protein kinase-1 (PDPK1) TT9QBI6 PDPK1_HUMAN Modulator [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
3-phosphoinositide-dependent protein kinase 1 (PDPK1) OTT09ZVP PDPK1_HUMAN Drug Response [3]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Drug Response [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 3.1874 4.7327 2.8439 12.5634
ES1 GDSC1 -1.3573 3.1955 -1.6482 62.4676
SJSA-1 GDSC1 -0.6759 1.317 -0.6863 58.2276
EW-16 GDSC1 -0.2806 4.3978 -0.786 52.5764
ES4 GDSC1 0.5698 3.3764 0.4065 43.4909
SK-ES-1 GDSC1 0.7149 4.1936 0.3602 42.4224
ES6 GDSC1 0.9018 2.6312 0.8716 38.8984
EW-1 GDSC1 0.9199 3.6546 0.7262 39.4632
EW-13 GDSC1 0.934 3.2715 0.821 38.9221
MHH-ES-1 GDSC1 1.0283 3.1431 0.9443 37.6183
HOS GDSC1 1.0601 2.6617 1.0347 36.9
EW-18 GDSC1 1.0993 3.8357 0.8777 37.4484
SK-PN-DW GDSC1 1.1919 3.5408 1.0475 35.9307
NOS-1 [Human HNSCC] GDSC1 1.2716 2.7653 1.2474 34.2538
A-673 GDSC1 1.7718 4.4773 1.423 30.0452
U2OS GDSC1 1.7988 6.1609 0.7927 33.2888
G-292 clone A141B1 GDSC1 2.1627 4.2841 1.9107 24.6232
ES5 GDSC1 2.2016 3.7237 2.1053 23.1014
EW-7 GDSC1 2.2812 3.3828 2.2497 21.6847
SaOS-2 GDSC1 2.378 3.9793 2.2354 21.2082
ES8 GDSC1 2.7905 8.0514 0.8952 27.5437
NY GDSC1 2.9045 3.907 2.8285 14.1888
MG-63 GDSC1 3.112 4.5158 2.8536 12.877
ES7 GDSC1 3.3037 6.3398 2.209 16.7791
EW-24 GDSC1 3.3644 3.8181 3.3462 8.0614
EW-11 GDSC1 3.3959 9.3783 0.7922 25.3966
TC-71 GDSC1 3.3981 4.1129 3.3091 8.1177
H-EMC-SS GDSC1 3.543 5.533 2.8258 11.0576
CAL-72 GDSC1 3.557 4.9922 3.0994 8.8883
HuO-3N1 GDSC1 3.6067 4.4878 3.3823 6.512
CHSA0108 GDSC1 3.6653 4.8684 3.2629 7.1505
CAL-78 GDSC1 3.7726 4.7888 3.4031 5.6013
EW-3 GDSC1 3.9839 8.4939 1.7396 17.3659
HuO9 GDSC1 4.3827 5.9177 3.3383 3.9848
CHSA8926 GDSC1 6.6763 8.392 3.4462 0.312
CHSA0011 GDSC1 6.8182 8.8823 3.3257 0.5705
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 146 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 1.2759 3.1022 1.2155 34.4174
NALM-6 GDSC1 -0.6286 2.0259 -0.6799 57.2819
NB4 GDSC1 -0.5844 3.1034 -0.7899 56.0516
Karpas-231 GDSC1 -0.3055 0.9665 -0.3061 53.8102
WIL2 NS GDSC1 -0.1877 2.6733 -0.2882 52.1377
SU-DHL-5 GDSC1 -0.1609 1.8826 -0.1819 51.9575
P30/OHK GDSC1 -0.1392 2.6233 -0.2293 51.6006
KE-37 GDSC1 -0.088 3.2907 -0.2897 50.9483
MOLT-4 GDSC1 -0.0098 1.5337 -0.0145 50.122
CCRF-CEM GDSC1 0.0414 3.7505 -0.2546 49.5708
BL-41 GDSC1 0.1221 2.986 -0.0046 48.6097
P12-Ichikawa GDSC1 0.1452 3.6233 -0.1103 48.4535
SIG-M5 GDSC1 0.156 1.5856 0.1525 48.0584
KCL-22 GDSC1 0.1955 3.4613 -0.0182 47.8671
DND-41 GDSC1 0.2061 3.9977 -0.1398 47.887
GR-ST GDSC1 0.2885 3.0212 0.1686 46.6747
PF-382 GDSC1 0.3536 3.1443 0.2173 45.9475
QIMR-WIL GDSC1 0.3736 3.2278 0.2233 45.7459
Reh GDSC1 0.4578 2.7275 0.3929 44.5183
HEL GDSC1 0.4854 3.1273 0.3626 44.363
SU-DHL-8 GDSC1 0.4898 3.4092 0.3129 44.4634
SU-DHL-1 GDSC1 0.6741 2.9209 0.5979 41.9268
RPMI-8402 GDSC1 0.7399 3.4543 0.5749 41.4879
697 GDSC1 0.7407 2.855 0.6777 41.0543
CTV-1 GDSC1 0.7998 3.6173 0.6041 40.8968
EoL-1 GDSC1 0.8007 3.1133 0.7045 40.4692
MHH-PREB-1 GDSC1 0.8086 3.1361 0.7093 40.3872
H9 GDSC1 0.8189 3.5966 0.6297 40.6448
OCI-AML-2 GDSC1 0.9082 2.8517 0.8561 38.9349
SUP-T1 GDSC1 0.9162 4.1757 0.585 40.0702
CESS GDSC1 0.9163 4.1236 0.6001 40.011
NU-DUL-1 GDSC1 0.9738 3.1342 0.8871 38.3034
MY-M12 GDSC1 1.0174 4.3347 0.6478 39.0652
SU-DHL-6 GDSC1 1.0455 4.0005 0.7756 38.3123
MV4-11 GDSC1 1.1288 3.0386 1.0671 36.2531
DEL GDSC1 1.1989 3.3569 1.0916 35.6409
HL-60 GDSC1 1.2611 3.1035 1.1994 34.6093
Daudi GDSC1 1.2613 3.8001 1.0633 35.3724
Ramos.2G6.4C10 GDSC1 1.325 4.06 1.064 34.9397
A3/Kawakami GDSC1 1.3253 3.8133 1.1298 34.5804
Namalwa GDSC1 1.3333 3.4748 1.2144 34.0483
NOMO-1 GDSC1 1.3341 3.6918 1.1687 34.3045
MN-60 GDSC1 1.3564 3.9991 1.1152 34.4536
SR GDSC1 1.3733 2.439 1.3691 32.86
KOPN-8 GDSC1 1.3765 2.8532 1.3499 32.9586
U-698-M GDSC1 1.4478 4.6058 1.0286 34.3117
HC-1 GDSC1 1.4653 5.2873 0.8002 35.3161
BC-1 GDSC1 1.4796 3.6854 1.3285 32.4312
MEG-01 GDSC1 1.5034 3.5069 1.3924 31.8951
TK [Human B-cell lymphoma] GDSC1 1.5064 4.2871 1.1951 33.0323
Karpas-422 GDSC1 1.5099 3.579 1.3848 31.9004
ALL-SIL GDSC1 1.5571 3.4031 1.47 31.0803
DB GDSC1 1.564 3.4925 1.4609 31.0934
Granta-519 GDSC1 1.5694 3.6854 1.4262 31.2736
P32/ISH GDSC1 1.5704 3.8742 1.3818 31.5375
MOLM-13 GDSC1 1.5757 5.6993 0.7537 34.8266
OCI-Ly19 GDSC1 1.5907 3.9711 1.3785 31.4301
HAL-01 GDSC1 1.5917 4.5027 1.2191 32.3538
A4/Fukuda GDSC1 1.5922 4.4246 1.2451 32.2032
VAL GDSC1 1.6551 5.7696 0.8083 34.0817
ML-2 GDSC1 1.6703 4.0028 1.4568 30.4596
Karpas-45 GDSC1 1.7005 3.646 1.5776 29.521
WSU-NHL GDSC1 1.702 3.0999 1.6685 28.9363
Sc-1 GDSC1 1.7247 5.6123 0.9461 32.9849
ALL-PO GDSC1 1.7422 4.9573 1.2214 31.4072
AMO1 GDSC1 1.7479 4.8047 1.2835 31.0177
VL51 GDSC1 1.7491 5.4918 1.0208 32.4544
SUP-M2 GDSC1 1.8022 3.9573 1.613 28.6794
Karpas-620 GDSC1 1.8245 3.2549 1.78 27.4761
JSC-1 GDSC1 1.8436 3.4109 1.7774 27.3761
Farage GDSC1 1.8546 5.7446 1.0277 31.7872
Mono-Mac-6 GDSC1 1.8576 8.3825 -0.1591 36.6498
SU-DHL-16 GDSC1 1.8907 3.5245 1.8082 26.8928
Ku812 GDSC1 1.9657 3.9582 1.7912 26.5555
HH [Human lymphoma] GDSC1 1.9735 4.2557 1.7136 27.0159
IM-9 GDSC1 1.9978 3.7582 1.8759 25.8127
SU-DHL-4 GDSC1 2.0399 3.0471 2.0273 24.5809
L-363 GDSC1 2.0513 5.2111 1.4531 28.2184
PL-21 GDSC1 2.1036 5.2085 1.5095 27.572
KMS-12-BM GDSC1 2.1214 4.7646 1.7 26.2531
RS4;11 GDSC1 2.1279 4.5563 1.7819 25.678
DoHH2 GDSC1 2.1625 4.8517 1.7115 25.9466
MOLP-8 GDSC1 2.1786 3.2739 2.1535 22.9264
CTB-1 GDSC1 2.1855 5.2507 1.5789 26.6758
SUP-B15 GDSC1 2.1912 3.5503 2.1281 23.0145
RPMI-6666 GDSC1 2.1983 3.618 2.1233 23.0026
YT GDSC1 2.2313 3.3577 2.1998 22.3088
NK-92MI GDSC1 2.2823 3.3985 2.2489 21.6835
JJN-3 GDSC1 2.2831 3.3139 2.2596 21.61
Jiyoye GDSC1 2.2986 5.0723 1.7704 24.8047
BC-3 GDSC1 2.3049 4.2864 2.0647 22.7793
EB2 GDSC1 2.3101 4.4335 2.0215 23.044
CA46 GDSC1 2.3154 3.4019 2.2836 21.2595
LAMA-84 GDSC1 2.333 4.9929 1.8384 24.1612
Karpas-299 GDSC1 2.3372 3.2966 2.3182 20.905
RPMI-8866 GDSC1 2.368 4.4641 2.0737 22.3657
ST486 GDSC1 2.3692 3.1726 2.3608 20.4379
BE-13 GDSC1 2.3864 4.7287 1.9976 22.7871
MC116 GDSC1 2.4133 5.057 1.8978 23.3254
LC4-1 GDSC1 2.4658 4.8533 2.0344 22.1041
K-562 GDSC1 2.4922 5.1463 1.9443 22.5874
BALL-1 GDSC1 2.5166 6.2379 1.4903 25.467
Raji GDSC1 2.5177 4.7598 2.1261 21.1883
EHEB GDSC1 2.5308 3.1681 2.5272 18.3877
DG-75 GDSC1 2.5641 3.3294 2.5529 18.0193
ME1 GDSC1 2.566 3.3663 2.5521 18.0128
SK-MM-2 GDSC1 2.5819 7.2013 1.105 27.4221
SCC-3 GDSC1 2.6229 3.2313 2.6191 17.2376
OCI-M1 GDSC1 2.63 5.5583 1.9108 22.1044
LP-1 GDSC1 2.635 3.3621 2.6245 17.1287
JURL-MK1 GDSC1 2.6598 4.4749 2.3849 18.6097
RPMI-8226 GDSC1 2.6662 5.8419 1.8208 22.5399
L-428 GDSC1 2.685 5.0945 2.1676 20.018
GDM-1 GDSC1 2.7212 7.1008 1.2876 25.6819
ARH-77 GDSC1 2.7344 4.5695 2.4301 17.8908
TUR GDSC1 2.7372 4.9668 2.2756 18.9789
L-540 GDSC1 2.7694 5.9556 1.8726 21.6708
HDLM-2 GDSC1 2.8658 4.042 2.7505 14.9368
KMOE-2 GDSC1 2.8687 4.3991 2.6372 15.7075
RL GDSC1 2.9637 3.624 2.9452 13.0708
MLMA GDSC1 3.0541 5.4884 2.3715 16.7131
OCI-AML-5 GDSC1 3.0683 5.6791 2.2975 17.193
OCI-AML-3 GDSC1 3.0751 4.472 2.8316 13.228
HT GDSC1 3.1771 7.0311 1.7539 20.5749
WSU-DLCL2 GDSC1 3.1848 3.7859 3.1583 10.3595
KG-1 GDSC1 3.1883 5.5724 2.4656 15.3835
KM-H2 GDSC1 3.1996 4.2541 3.046 11.0414
MOLT-16 GDSC1 3.2264 7.0213 1.8045 20.0102
SUP-HD1 GDSC1 3.2318 4.9812 2.7807 12.8147
U266B1 GDSC1 3.2413 4.3407 3.0592 10.7244
KY821 GDSC1 3.2511 4.2663 3.0971 10.4034
EM-2 GDSC1 3.2616 4.4129 3.0531 10.6619
Hs 445 GDSC1 3.2709 4.8725 2.869 11.9672
Loucy GDSC1 3.3254 4.2321 3.1896 9.3507
OPM-2 GDSC1 3.35 4.2366 3.2144 9.0434
BV-173 GDSC1 3.3654 4.3972 3.1694 9.2843
EJM GDSC1 3.3752 4.2086 3.2516 8.6454
THP-1 GDSC1 3.3837 4.8963 2.9726 10.6516
RC-K8 GDSC1 3.4116 4.0093 3.3553 7.7253
JVM-3 GDSC1 3.4388 4.1408 3.3441 7.6506
ATN-1 GDSC1 3.4591 3.9709 3.4173 7.0342
P31/FUJ GDSC1 3.5196 3.8926 3.5006 6.1274
JVM-2 GDSC1 3.5277 5.9563 2.6049 12.8269
ROS-50 GDSC1 3.6917 4.6016 3.4152 5.8654
NKM-1 GDSC1 5.0552 13.3227 0.1862 22.4084
L-1236 GDSC1 5.8836 9.8212 2.4691 6.6258
⏷ Show the Full List of 146 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-50 GDSC1 -0.3157 1.6051 -0.3282 53.8647
TE-12 GDSC1 0.7272 3.2036 0.61 41.4504
HCE-4 GDSC1 1.1973 2.4008 1.1908 35.074
KYSE-220 GDSC1 2.4068 4.21 2.1998 21.286
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 2.5658 4.1397 2.3945 19.0612
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-MC-IXC GDSC1 -0.0841 3.9359 -0.4397 50.8386
SJNB-14 GDSC1 0.5738 2.5581 0.534 43.0075
KP-N-YS GDSC1 0.7591 7.4182 -0.8248 44.5315
SJNB-13 GDSC1 1.6361 3.3122 1.5702 29.9639
SJNB-6 GDSC1 1.7894 4.1089 1.557 29.1101
SiMa GDSC1 2.0522 5.8035 1.2086 29.6577
SJNB-7 GDSC1 2.1733 4.8395 1.7276 25.7799
NB(TU)1 GDSC1 2.1784 3.1577 2.1637 22.8627
IMR-5 GDSC1 2.323 7.4579 0.7315 30.6818
NH-12 GDSC1 2.3298 3.7537 2.2381 21.4706
CHP-126 GDSC1 2.4248 3.2133 2.416 19.7449
NB69 GDSC1 2.487 3.124 2.4839 18.9317
CHP-212 GDSC1 2.4959 3.1374 2.4925 18.8222
LA-N-6 GDSC1 2.5299 3.1449 2.527 18.3947
SK-N-SH GDSC1 2.6248 4.0966 2.4718 18.2001
TGW GDSC1 2.7108 5.0591 2.2094 19.588
SJNB-10 GDSC1 3.0418 4.7876 2.669 14.5768
SK-N-DZ GDSC1 3.0816 5.4065 2.4366 16.0996
Kelly GDSC1 3.1801 4.8441 2.7884 13.0096
SK-N-BE(2)-M17 GDSC1 3.2153 4.5034 2.9681 11.5158
GOTO GDSC1 3.2961 5.128 2.7788 12.5238
NB1 GDSC1 3.4072 3.8493 3.3871 7.5388
SJNB-5 GDSC1 3.4151 3.989 3.3647 7.6412
SK-N-AS GDSC1 3.429 4.6177 3.1432 9.1571
SJNB-12 GDSC1 3.4512 4.3423 3.2823 8.0246
SK-N-FI GDSC1 3.4978 4.0775 3.4289 6.7361
MHH-NB-11 GDSC1 3.5554 5.8023 2.706 11.9305
GI-ME-N GDSC1 3.619 5.2131 3.0526 8.9763
KP-N-YN GDSC1 4.4989 6.0981 3.332 3.7118
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 1.7222 3.3804 1.6518 28.9174
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-51 GDSC1 -1.885 -0.5127 -1.8851 73.3038
CAL-85-1 GDSC1 -0.3722 1.6066 -0.3861 54.5409
EFM-192A GDSC1 -0.286 2.7829 -0.4102 53.1869
MCF-7 GDSC1 0.046 1.5814 0.0411 49.4293
MDA-MB-231 GDSC1 1.496 3.5 1.3857 31.9826
DU4475 GDSC1 1.6197 3.805 1.4529 30.7965
EFM-19 GDSC1 1.7382 3.7694 1.5906 29.2086
OCUB-M GDSC1 1.9002 3.6749 1.7883 26.9643
ZR-75-30 GDSC1 2.0657 4.2779 1.8071 25.8679
MRK-nu-1 GDSC1 2.1553 3.3139 2.1244 23.2546
CAMA-1 GDSC1 2.176 6.8957 0.8481 30.8884
HCC1806 GDSC1 2.2381 3.5869 2.1722 22.4461
HCC202 GDSC1 2.3299 4.4069 2.052 22.7263
HCC1569 GDSC1 2.4349 3.7208 2.3593 20.0512
T-47D GDSC1 2.4534 3.422 2.4277 19.4952
AU565 GDSC1 2.4565 3.2372 2.4474 19.3505
COLO 824 GDSC1 2.4726 3.4763 2.4414 19.2911
HCC1937 GDSC1 2.4902 4.0003 2.3522 19.7774
HCC1395 GDSC1 2.5517 3.5468 2.5162 18.3299
HCC1500 GDSC1 2.5897 3.1365 2.588 17.6397
JIMT-1 GDSC1 2.6535 4.6841 2.3001 19.2415
HCC1954 GDSC1 2.8437 3.9876 2.7414 15.1244
HCC1599 GDSC1 2.9677 5.8363 2.1249 18.9282
BT-474 GDSC1 3.0274 5.3283 2.4177 16.4995
HDQ-P1 GDSC1 3.0664 4.1094 2.9493 12.4471
HCC38 GDSC1 3.1511 4.0258 3.0664 11.1691
MDA-MB-361 GDSC1 3.172 3.9906 3.0989 10.8297
MDA-MB-157 GDSC1 3.2336 4.2885 3.0703 10.6872
BT-549 GDSC1 3.2758 4.0166 3.2051 9.5175
CAL-148 GDSC1 3.3055 4.1713 3.1892 9.4618
HCC2218 GDSC1 3.3546 4.8057 2.984 10.704
MDA-MB-330 GDSC1 3.3747 4.1606 3.2678 8.5343
MDA-MB-453 GDSC1 3.3801 6.3553 2.2728 15.974
MDA-MB-468 GDSC1 3.3997 6.765 2.0901 17.2357
MDA-MB-415 GDSC1 3.4069 14.5825 -1.7933 34.5621
CAL-120 GDSC1 3.4585 4.1757 3.3532 7.4794
MFM-223 GDSC1 3.4865 3.9215 3.459 6.5968
HCC2157 GDSC1 3.4912 4.126 3.4058 6.9328
BT-20 GDSC1 3.4983 4.0332 3.443 6.6366
HCC1428 GDSC1 3.518 4.027 3.4663 6.3659
MDA-MB-436 GDSC1 3.5765 4.3577 3.4076 6.4733
HCC1419 GDSC1 3.5916 4.1337 3.5118 5.6441
Evsa-T GDSC1 3.6347 4.3714 3.4622 5.7818
HCC70 GDSC1 3.6815 4.4267 3.4856 5.3802
Hs 578T GDSC1 3.6864 5.3208 3.0629 8.6102
MDA-MB-175-VII GDSC1 3.9412 5.1243 3.3881 5.0434
UACC-893 GDSC1 4.0935 5.56 3.2965 5.2186
BT-483 GDSC1 4.2197 5.5429 3.4031 3.9696
HCC1187 GDSC1 5.5016 10.566 1.8685 11.6242
UACC-812 GDSC1 5.7355 8.6562 2.9097 3.9736
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GB-1 GDSC1 -0.5015 1.8688 -0.5343 55.959
8-MG-BA GDSC1 0.0613 2.3116 0.0184 49.2641
H4 GDSC1 0.1336 2.0894 0.1107 48.3676
Daoy GDSC1 0.2732 2.8751 0.1755 46.8127
SK-MG-1 GDSC1 0.893 2.5137 0.8715 38.9609
ONS-76 GDSC1 1.2474 3.36 1.1434 35.0243
YKG-1 GDSC1 1.3085 2.8016 1.2831 33.8004
SF295 GDSC1 1.4184 3.6445 1.2711 33.1638
A-172 GDSC1 1.4649 3.1699 1.4079 32.0427
GaMG GDSC1 1.9382 3.0781 1.9191 25.8929
SF268 GDSC1 1.9384 3.704 1.8235 26.508
SF126 GDSC1 2.1676 3.5023 2.1109 23.2676
D-566MG GDSC1 2.2285 3.3669 2.1956 22.3529
Onda 11 GDSC1 2.2398 5.1301 1.685 25.6903
MOG-G-UVW GDSC1 2.2782 3.7395 2.1851 22.1243
AM-38 GDSC1 2.3365 3.7395 2.2485 21.362
SW1783 GDSC1 2.4136 4.2488 2.1949 21.2819
KS-1 [Human Krukenberg tumour] GDSC1 2.4292 3.5879 2.3781 19.9616
M059J GDSC1 2.4363 4.6946 2.0638 22.0601
NMC-G1 GDSC1 2.5159 3.0697 2.5145 18.5598
Becker GDSC1 2.5237 2.9765 2.5234 18.4553
MOG-G-CCM GDSC1 2.5396 3.5127 2.508 18.4562
CAS-1 GDSC1 2.5645 3.5198 2.5336 18.1402
Hs 683 GDSC1 2.6215 4.4479 2.3533 19.0385
YH-13 GDSC1 2.7935 4.0208 2.6776 15.8433
D-423MG GDSC1 2.8062 4.0928 2.6706 15.8189
GI-1 GDSC1 2.8466 5.1865 2.2959 18.2779
U-87MG ATCC GDSC1 3.0604 3.7925 3.0229 11.9861
SNB-75 GDSC1 3.085 4.3459 2.8894 12.7639
Onda 10 GDSC1 3.1139 8.2412 1.1022 24.9278
KALS-1 GDSC1 3.2008 4.6357 2.8987 12.0943
LN-18 GDSC1 3.2272 3.8172 3.1986 9.8431
SF539 GDSC1 3.2787 6.8889 1.9178 18.9921
PFSK-1 GDSC1 3.2855 4.4213 3.0752 10.3779
LN-229 GDSC1 3.3256 6.6669 2.0699 17.7015
KNS-42 GDSC1 3.3365 3.8705 3.3067 8.4862
42-MG-BA GDSC1 3.341 4.0435 3.2685 8.7163
D283 Med GDSC1 3.3428 3.9167 3.3037 8.4681
DBTRG-05MG GDSC1 3.4439 3.978 3.3989 7.2457
U-251MG GDSC1 3.4754 3.8701 3.457 6.6751
D-263MG GDSC1 3.5047 4.0908 3.4322 6.6755
T98G GDSC1 3.5094 4.0428 3.4523 6.5101
KINGS-1 GDSC1 3.5155 4.332 3.3543 7.1724
D-392MG GDSC1 3.5373 4.2552 3.408 6.6714
SW1088 GDSC1 3.5374 4.0732 3.4735 6.2081
U-118MG GDSC1 3.5449 4.0493 3.4891 6.0588
KNS-81-FD GDSC1 3.5513 4.1136 3.4752 6.119
LN-405 GDSC1 3.5514 4.0319 3.5014 5.9382
D-542MG GDSC1 3.5872 4.165 3.4957 5.7814
DK-MG GDSC1 3.7089 4.5809 3.4417 5.5847
LNZTA3WT4 GDSC1 3.7255 4.385 3.5489 4.6953
D-502MG GDSC1 4.096 5.6906 3.2333 5.7076
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 0.9005 4.4454 0.4861 40.5551
TGBC1TKB GDSC1 3.1975 4.1418 3.0817 10.8036
TGBC24TKB GDSC1 3.4937 4.447 3.2838 7.7979
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 GDSC1 0.6129 3.2023 0.4868 42.857
MFE-319 GDSC1 0.6532 2.5062 0.6219 41.9899
AN3-CA GDSC1 0.9274 2.6668 0.8954 38.5902
MFE-296 GDSC1 2.0124 3.1847 1.9873 25.004
EN GDSC1 3.2952 3.8028 3.2743 8.9442
KLE GDSC1 3.4465 4.2622 3.3085 7.8605
MFE-280 GDSC1 4.3295 8.5856 1.9757 14.4848
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
786-O GDSC1 -1.1192 2.1031 -1.206 62.1347
ACHN GDSC1 1.3315 2.5958 1.3205 33.4245
769-P GDSC1 1.36 3.3647 1.2641 33.583
KMRC-20 GDSC1 1.5122 1.9738 1.5122 31.0974
BFTC-909 GDSC1 1.8236 4.5477 1.4556 29.5343
TK-10 GDSC1 1.8512 4.0836 1.6317 28.2659
VMRC-RCW GDSC1 2.0659 3.3123 2.0296 24.4068
VMRC-RCZ GDSC1 2.0686 3.5592 1.9941 24.6193
HA7-RCC GDSC1 2.1837 3.6238 2.1064 23.2005
A-704 GDSC1 2.2792 3.3845 2.2474 21.712
LB2241-RCC GDSC1 2.3109 3.7177 2.2253 21.6666
LB1047-RCC GDSC1 2.3969 3.6555 2.331 20.4622
SW13 GDSC1 2.4328 3.3567 2.413 19.715
OS-RC-2 GDSC1 2.4981 3.8427 2.4011 19.4038
BB65-RCC GDSC1 2.5159 3.3151 2.5038 18.628
UO-31 GDSC1 2.5268 3.9808 2.3974 19.2629
RCC10RGB GDSC1 2.5349 6.8687 1.2161 27.0274
RXF 393L GDSC1 2.5805 3.557 2.5455 17.9669
KMRC-1 GDSC1 2.6216 3.1884 2.6191 17.2457
Caki-1 GDSC1 2.8472 10.7994 -0.4025 32.7808
SW156 GDSC1 3.0156 4.1446 2.883 13.1873
LB996-RCC GDSC1 3.4489 4.3659 3.2703 8.1237
SN12C GDSC1 3.4668 4.236 3.3401 7.5286
CAL-54 GDSC1 3.4817 4.0905 3.4072 6.9755
A-498 GDSC1 4.8457 6.721 3.2631 3.3679
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCT 15 GDSC1 -1.1765 -0.2035 -1.1765 64.6971
COLO205 GDSC1 -0.8172 1.6707 -0.8489 59.5878
LoVo GDSC1 -0.523 1.9238 -0.5607 56.1748
RKO GDSC1 -0.1489 1.8488 -0.1676 51.8153
LS123 GDSC1 -0.0891 3.1229 -0.2573 50.9784
SW620 GDSC1 0.4633 1.9481 0.4562 44.2419
LS1034 GDSC1 0.767 2.6197 0.7313 40.6016
SW626 GDSC1 0.848 3.2718 0.728 40.0012
KM12 GDSC1 1.1489 3.3833 1.0326 36.3062
LS411N GDSC1 1.3527 3.8761 1.1437 34.3216
HT-29 GDSC1 1.3767 3.5132 1.2538 33.5356
NCI-H747 GDSC1 1.5747 2.6453 1.568 30.3582
LS180 GDSC1 1.5864 3.2354 1.5285 30.5336
COLO 320HSR GDSC1 1.7135 3.6171 1.5979 29.3131
T84 GDSC1 1.7921 2.9477 1.7765 27.6972
HCC2998 GDSC1 1.8485 3.4005 1.7843 27.3022
SNU-C2B GDSC1 2.1268 4.9352 1.6414 26.6036
SW48 GDSC1 2.3286 3.112 2.3221 20.9329
GP5d GDSC1 2.5074 3.0912 2.5055 18.669
HT-55 GDSC1 2.6046 3.2034 2.6013 17.4631
HCT 116 GDSC1 2.9803 4.4846 2.7254 14.4863
SW837 GDSC1 3.0457 4.302 2.8628 13.1625
MDST8 GDSC1 3.1609 4.7422 2.8123 12.9285
C2BBe1 GDSC1 3.1733 5.0332 2.698 13.7136
CCK-81 GDSC1 3.2786 4.2153 3.1449 9.9185
SW1463 GDSC1 3.3798 3.9851 3.3272 8.0969
CL-11 GDSC1 3.4454 4.5045 3.209 8.5896
CaR-1 GDSC1 3.4874 4.1773 3.3838 7.1078
NCI-H716 GDSC1 3.5138 4.286 3.371 7.0597
SW1417 GDSC1 3.514 4.1539 3.4208 6.7037
RCM-1 [Human ESC] GDSC1 3.5708 3.9785 3.5373 5.5835
LS513 GDSC1 3.768 4.7454 3.4198 5.4915
SW948 GDSC1 3.8144 4.7206 3.4753 4.8632
HT115 GDSC1 3.8173 4.4909 3.5895 3.9661
COLO 678 GDSC1 3.8871 5.4324 3.1877 6.8272
SNU-C1 GDSC1 5.9602 7.7695 3.392 0.9107
CW-2 GDSC1 6.4577 8.3734 3.37 0.6317
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 3.2104 3.968 3.1468 10.2855
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-7 GDSC1 0.176 1.9849 0.1603 47.8347
SNU-398 GDSC1 0.7107 2.9457 0.6335 41.4842
Hep 3B2.1-7 GDSC1 1.2433 2.2863 1.2405 34.4763
SK-HEP-1 GDSC1 1.4396 3.4926 1.3261 32.7011
Hep-G2/C3A GDSC1 1.5821 2.3869 1.5812 30.2294
HLE GDSC1 1.6348 3.1363 1.5932 29.8263
JHH-1 GDSC1 2.0531 3.78 1.931 25.1246
JHH-6 GDSC1 2.1506 2.7295 2.1501 23.1207
SNU-423 GDSC1 2.272 3.9673 2.123 22.5735
JHH-4 GDSC1 2.2919 3.321 2.2681 21.5022
SNU-387 GDSC1 2.3781 4.0924 2.2039 21.42
SNU-449 GDSC1 2.5646 3.946 2.4479 18.7054
Huh-7 GDSC1 3.2204 4.1579 3.1014 10.5401
JHH-2 GDSC1 3.325 4.005 3.262 8.8507
SNU-475 GDSC1 3.4651 3.8377 3.4512 6.7753
HuH-1 GDSC1 3.6192 4.1285 3.5434 5.2723
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 168 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H810 GDSC1 -0.8184 3.7308 -1.1875 57.5976
Lu-135 GDSC1 -0.5094 1.4521 -0.5207 56.2171
CAL-12T GDSC1 -0.1709 2.4397 -0.2399 51.9939
LC-2/ad GDSC1 -0.0842 2.6784 -0.1782 50.9682
A-427 GDSC1 -0.0344 2.5678 -0.1104 50.4014
COR-L23 GDSC1 0.0405 2.3584 -0.0078 49.5158
IA-LM GDSC1 0.1623 1.9379 0.1484 48.0005
NCI-H2342 GDSC1 0.2302 2.8941 0.1266 47.3283
NCI-H460 GDSC1 0.2613 1.69 0.2572 46.748
NCI-H727 GDSC1 0.2816 2.4899 0.2331 46.6104
HOP-62 GDSC1 0.4584 3.3029 0.3006 44.7776
SBC-3 GDSC1 0.4613 2.8965 0.3738 44.5463
HCC44 GDSC1 0.4618 2.1163 0.4483 44.2871
NCI-H3122 GDSC1 0.5963 3.4291 0.4243 43.2077
NCI-H1299 GDSC1 0.7525 2.8734 0.6879 40.9167
NCI-H2009 GDSC1 0.8128 2.766 0.7648 40.0949
LXF 289 GDSC1 0.857 3.036 0.777 39.7057
SK-MES-1 GDSC1 1.2894 3.3321 1.1938 34.4557
ABC-1 GDSC1 1.3072 4.5063 0.9089 35.8495
NCI-H2405 GDSC1 1.3634 3.5825 1.2249 33.7906
LCLC-97TM1 GDSC1 1.4073 3.0505 1.362 32.6897
SK-LU-1 GDSC1 1.496 3.5189 1.3821 32.0047
NCI-H2369 GDSC1 1.5318 3.6183 1.4002 31.668
NCI-H520 GDSC1 1.5579 2.8671 1.5384 30.6484
NCI-H526 GDSC1 1.7441 3.7861 1.593 29.1576
LCLC-103H GDSC1 1.747 3.5984 1.6381 28.8532
NCI-H2110 GDSC1 1.8209 3.3601 1.7611 27.6181
DMS 273 GDSC1 1.8638 3.1519 1.8339 26.8915
SBC-5 GDSC1 2.0776 3.0558 2.0659 24.1031
NCI-H2122 GDSC1 2.0872 3.3791 2.0434 24.1886
NCI-H522 GDSC1 2.1031 3.1107 2.0886 23.8027
NCI-H2170 GDSC1 2.1186 4.7728 1.6939 26.3086
SW1271 GDSC1 2.1208 3.4999 2.0609 23.8725
NCI-H1651 GDSC1 2.1622 4.0086 1.992 24.0833
NCI-H2085 GDSC1 2.1835 3.9479 2.0316 23.6963
NCI-H2087 GDSC1 2.1843 3.2444 2.1624 22.8343
NCI-H2030 GDSC1 2.1996 2.9965 2.1946 22.5361
NCI-H847 GDSC1 2.2006 3.1826 2.185 22.591
NCI-H292 GDSC1 2.2082 7.2466 0.7178 31.3494
NCI-H1770 GDSC1 2.2261 3.3705 2.1926 22.3866
HCC78 GDSC1 2.252 5.8344 1.4018 27.4131
NCI-H290 GDSC1 2.2629 3.4813 2.2165 22.0101
HARA [Human squamous cell lung carcinoma] GDSC1 2.2669 3.4512 2.2252 21.9294
NCI-H1048 GDSC1 2.2792 6.0444 1.3373 27.6537
NCI-H358 GDSC1 2.2874 3.3541 2.2597 21.5831
NCI-H1944 GDSC1 2.2962 3.8488 2.1795 22.0557
NCI-H1355 GDSC1 2.2998 3.1599 2.2897 21.3161
NCI-H1648 GDSC1 2.3266 4.7395 1.9294 23.5796
PC-14 GDSC1 2.3478 3.6837 2.2723 21.1387
NCI-H2347 GDSC1 2.3919 3.6985 2.3172 20.5823
NCI-H650 GDSC1 2.3952 5.1011 1.8608 23.6746
BEN GDSC1 2.4013 4.0731 2.2348 21.079
NCI-H226 GDSC1 2.4172 4.0049 2.2713 20.7415
NCI-H1975 GDSC1 2.4283 3.1755 2.4217 19.6877
LB647-SCLC GDSC1 2.446 3.5112 2.4082 19.6655
NCI-H1568 GDSC1 2.4553 3.784 2.3679 19.8748
HCC33 GDSC1 2.4597 3.0392 2.4581 19.2639
Calu-3 GDSC1 2.4949 3.3266 2.481 18.9016
NCI-H2135 GDSC1 2.5292 4.7339 2.1482 20.972
HCC15 GDSC1 2.536 3.7732 2.458 18.8038
NCI-H1869 GDSC1 2.5752 3.2824 2.5676 17.858
EPLC-272H GDSC1 2.6485 3.56 2.6178 17.0891
IST-SL2 GDSC1 2.6614 6.487 1.5192 24.5528
NCI-H647 GDSC1 2.7153 4.3387 2.4927 17.5533
ChaGo-K-1 GDSC1 2.7204 3.7198 2.6688 16.3266
EBC-1 GDSC1 2.7205 3.6378 2.6832 16.232
PaCa-3 GDSC1 2.7369 3.9303 2.6399 16.4222
RERF-LC-MS GDSC1 2.7417 10.894 -0.5446 33.6917
NCI-H1304 GDSC1 2.7583 7.7693 1.0016 27.129
NCI-H1437 GDSC1 2.8482 3.9411 2.7586 14.9829
NCI-H2228 GDSC1 2.8723 4.2387 2.6968 15.2702
NCI-H211 GDSC1 2.8773 6.1031 1.9113 20.8783
COLO 668 GDSC1 2.8945 3.9081 2.8174 14.3209
NCI-H513 GDSC1 2.8993 3.9807 2.804 14.3834
NCI-H2227 GDSC1 2.9321 3.933 2.8522 13.87
NCI-H1734 GDSC1 2.9368 4.2545 2.7615 14.4653
RERF-LC-KJ GDSC1 2.9765 3.6949 2.9491 12.9689
LK-2 GDSC1 2.9847 3.8678 2.925 13.0782
NCI-H441 GDSC1 3.0008 4.1752 2.8571 13.4486
NCI-H2804 GDSC1 3.0045 4.1481 2.8698 13.3402
NCI-H2141 GDSC1 3.0068 5.03 2.5291 15.7779
UMC-11 GDSC1 3.0299 3.907 2.9651 12.5475
NCI-H1436 GDSC1 3.0419 4.1481 2.9105 12.8506
NCI-H2081 GDSC1 3.0904 4.6854 2.7624 13.6494
NCI-H596 GDSC1 3.1298 4.2186 2.9827 11.8646
Lu-99A GDSC1 3.1348 6.1332 2.1479 17.9835
NCI-H1694 GDSC1 3.1634 7.3498 1.5854 21.7581
COR-L105 GDSC1 3.2132 4.6583 2.9022 12.0066
HOP-92 GDSC1 3.2268 4.2175 3.0882 10.5979
Ms-1 GDSC1 3.2432 4.3637 3.0526 10.7621
A-549 GDSC1 3.2467 7.4863 1.5952 21.3248
NCI-H64 GDSC1 3.2705 7.6322 1.5452 21.5461
NCI-H1155 GDSC1 3.2899 4.3927 3.0911 10.2406
EKVX GDSC1 3.2984 4.3316 3.1237 9.9624
IST-SL1 GDSC1 3.3076 4.2784 3.1535 9.7022
NCI-H2722 GDSC1 3.3126 4.0407 3.2383 9.0828
NCI-H661 GDSC1 3.315 4.5032 3.0733 10.2405
Lu-65 GDSC1 3.3707 4.3295 3.2017 9.0238
Lu-139 GDSC1 3.3744 4.0552 3.3014 8.3034
NCI-H1876 GDSC1 3.3962 4.2784 3.2485 8.5553
NCI-H2023 GDSC1 3.4035 9.3768 0.7997 25.3257
NCI-H2803 GDSC1 3.4109 4.2121 3.2888 8.1906
NCI-H1581 GDSC1 3.4123 4.0204 3.3529 7.737
NCI-H1793 GDSC1 3.4124 3.9629 3.3685 7.6318
NCI-H838 GDSC1 3.4177 4.5978 3.1402 9.2344
NCI-H1836 GDSC1 3.4207 4.018 3.3628 7.6223
NCI-H2595 GDSC1 3.4241 4.2916 3.2733 8.2307
NCI-H2171 GDSC1 3.4311 4.6517 3.1304 9.2415
NCI-H1915 GDSC1 3.4363 4.0259 3.3775 7.434
NCI-H1623 GDSC1 3.447 4.1179 3.3606 7.4907
NCI-H1435 GDSC1 3.4479 4.035 3.3876 7.2998
NCI-H841 GDSC1 3.4529 4.1311 3.3626 7.4438
SHP-77 GDSC1 3.4539 4.6386 3.1595 8.9141
Calu-6 GDSC1 3.4654 4.4631 3.2474 8.2071
Lu-165 GDSC1 3.4687 3.9967 3.4211 6.9532
NCI-H1650 GDSC1 3.4699 5.5602 2.7436 12.0074
NCI-H1792 GDSC1 3.47 4.2591 3.3348 7.5486
NCI-H23 GDSC1 3.4897 4.2881 3.3446 7.3758
LC-1/sq GDSC1 3.4933 4.6457 3.1965 8.4475
RERF-LC-Sq1 GDSC1 3.4958 4.5565 3.2385 8.1223
NCI-H2591 GDSC1 3.5038 4.4222 3.3047 7.5933
HCC827 GDSC1 3.5069 4.3263 3.3476 7.2648
NCI-H2731 GDSC1 3.5123 4.3715 3.3348 7.3305
NCI-H1573 GDSC1 3.5149 4.0679 3.4506 6.4915
NCI-H2373 GDSC1 3.5173 4.1122 3.4388 6.56
NCI-H2196 GDSC1 3.5207 4.0917 3.4493 6.4677
NCI-H1963 GDSC1 3.5222 5.1699 2.9812 9.9507
NCI-H2869 GDSC1 3.5359 4.2957 3.3905 6.8044
NCI-H2461 GDSC1 3.5401 4.1352 3.4556 6.3181
NCI-H196 GDSC1 3.5438 3.9623 3.5119 5.9103
NCI-H748 GDSC1 3.5622 5.5295 2.8455 10.823
NCI-H1703 GDSC1 3.5649 4.2312 3.4467 6.2491
NCI-H2795 GDSC1 3.5807 4.4079 3.3906 6.5777
NCI-H1563 GDSC1 3.6272 4.1991 3.5256 5.3565
DMS 114 GDSC1 3.6463 4.2249 3.5357 5.1843
SW1573 GDSC1 3.6506 8.9464 1.2299 21.9111
LOU-NH91 GDSC1 3.7188 4.418 3.5271 4.891
NCI-H2172 GDSC1 3.7275 4.7185 3.3944 5.8643
NCI-H1781 GDSC1 3.7293 4.4583 3.5191 4.9025
NCI-H2444 GDSC1 3.8277 4.4612 3.6138 3.7335
NCI-H3255 GDSC1 3.8296 5.2314 3.2371 6.6631
NCI-H2029 GDSC1 3.8389 4.5559 3.5786 3.957
NCI-H720 GDSC1 3.9645 4.8889 3.5256 3.8716
NCI-H1666 GDSC1 3.9703 6.863 2.5437 11.555
NCI-H1693 GDSC1 3.984 5.6814 3.146 6.793
NCI-H446 GDSC1 4.0148 6.2521 2.8863 8.7252
NCI-H209 GDSC1 4.0235 6.9364 2.5513 11.3015
NCI-H1688 GDSC1 4.0759 5.1653 3.4793 3.8398
NCI-H82 GDSC1 4.3404 6.8369 2.8542 7.8669
COR-L88 GDSC1 4.5518 6.8592 3.0001 6.0942
COR-L95 GDSC1 4.5526 6.2436 3.2986 3.8212
NCI-H1755 GDSC1 4.665 6.6557 3.1771 4.4389
NCI-H69 GDSC1 4.8865 8.7156 2.334 10.1232
SBC-1 GDSC1 4.927 7.8582 2.778 6.7315
NCI-H345 GDSC1 4.9304 6.8211 3.2688 3.1409
DMS 79 GDSC1 5.0623 7.57 3.0035 4.7367
NCI-H187 GDSC1 5.0857 7.4932 3.0539 4.3209
NCI-H510A GDSC1 5.1522 9.2374 2.2683 9.8373
Lu-134-A GDSC1 5.3603 9.1129 2.4689 7.8572
NCI-H1092 GDSC1 5.9067 7.6179 3.4272 0.8071
NCI-H524 GDSC1 5.9783 7.6048 3.4618 0.6181
NCI-H1838 GDSC1 6.2109 8.6861 3.1427 1.8495
DMS 53 GDSC1 6.2907 8.0974 3.4051 0.6151
NCI-H2291 GDSC1 6.3252 8.4607 3.2829 1.0625
CPC-N GDSC1 6.3719 8.1033 3.4346 0.474
NCI-H1993 GDSC1 6.4746 8.0917 3.4772 0.3134
NCI-H2818 GDSC1 6.8606 8.9176 3.3293 0.5384
NCI-H322M GDSC1 7.1189 9.5258 3.2094 0.7716
⏷ Show the Full List of 168 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 2.6179 3.9196 2.5129 17.9615
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-8 GDSC1 -0.8464 3.7776 -1.2299 57.7807
KYSE-510 GDSC1 -0.2111 1.1415 -0.2124 52.6309
TE-1 GDSC1 0.302 3.4182 0.107 46.6519
KYSE-410 GDSC1 0.7463 4.3053 0.3613 42.1673
KYSE-140 GDSC1 0.7835 2.8314 0.7262 40.5011
KYSE-180 GDSC1 0.8794 2.5659 0.8536 39.1534
KYSE-450 GDSC1 0.9275 1.9991 0.9257 38.4172
KYSE-150 GDSC1 1.0155 3.1159 0.9347 37.759
KYSE-70 GDSC1 1.0391 3.1343 0.9572 37.4736
KYSE-270 GDSC1 1.0611 3.3262 0.9483 37.3657
T.T GDSC1 1.1256 3.0503 1.0621 36.3025
TE-15 GDSC1 1.2092 2.306 1.2055 34.9077
TE-10 GDSC1 1.457 3.6725 1.3068 32.7053
TE-9 GDSC1 1.8075 3.8884 1.6368 28.4953
OE21 GDSC1 1.9746 3.29 1.9353 25.5664
TE-6 GDSC1 2.0653 3.4131 2.015 24.5042
COLO 680N GDSC1 2.0794 3.2855 2.0472 24.2115
TE-11 GDSC1 2.2423 2.9595 2.2393 21.9905
TE-5 GDSC1 2.3109 3.6598 2.2371 21.5886
OE19 GDSC1 2.9177 4.0612 2.8016 14.2942
KYSE-520 GDSC1 2.9595 7.9035 1.1253 25.4964
OE33 GDSC1 3.1895 4.5156 2.936 11.8809
EC-GI-10 GDSC1 5.0977 7.3483 3.1282 3.7684
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TOV-112D GDSC1 -0.147 1.9105 -0.169 51.7862
SK-OV-3 GDSC1 0.4367 4.1034 0.0825 45.46
A2780 GDSC1 0.591 2.7609 0.5303 42.8804
IGROV-1 GDSC1 0.6477 3.3686 0.4925 42.5452
Kuramochi GDSC1 0.9301 2.3713 0.918 38.4453
OVCAR-8 GDSC1 1.5816 3.0384 1.5479 30.4412
OVCAR-4 GDSC1 1.9716 4.4263 1.6568 27.3946
OC 314 GDSC1 2.0568 4.815 1.6119 27.1899
OV-90 GDSC1 2.1185 3.7602 2.0069 24.2395
EFO-27 GDSC1 2.1316 3.3656 2.0926 23.603
RMG-I GDSC1 2.3695 3.5189 2.3251 20.665
TYK-nu GDSC1 2.5558 4.0566 2.4081 19.0246
FU-OV-1 GDSC1 2.8729 4.4953 2.6064 15.9025
EFO-21 GDSC1 2.9157 3.871 2.8492 13.9851
TOV-21G GDSC1 2.9451 3.6722 2.9189 13.3534
OAW42 GDSC1 2.961 4.0451 2.8535 13.6957
OVCAR-5 GDSC1 3.1896 3.953 3.128 10.5319
ES-2 GDSC1 3.3536 4.0154 3.2902 8.4969
OVCAR-3 GDSC1 3.3881 4.1138 3.298 8.2497
OVTOKO GDSC1 3.4152 4.0645 3.3431 7.7883
OVKATE GDSC1 3.4273 3.9389 3.3905 7.3977
Caov-3 GDSC1 3.4841 3.965 3.4462 6.6958
OVISE GDSC1 3.5443 3.8732 3.5307 5.7828
OAW28 GDSC1 3.607 4.5843 3.339 6.8356
Caov-4 GDSC1 5.0666 7.5863 2.9987 4.7618
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PSN1 GDSC1 -0.3326 2.6865 -0.4452 53.7246
MZ-PC-1 GDSC1 -0.0183 2.4162 -0.0758 50.2171
KP-1N GDSC1 1.1038 2.9872 1.0472 36.5342
KP-2 GDSC1 1.2433 1.8333 1.2433 34.4583
Panc 03.27 GDSC1 1.3008 3.6468 1.1426 34.6724
HuP-T4 GDSC1 1.3721 3.3446 1.2808 33.4052
PaTu 8988t GDSC1 1.4171 3.9006 1.2078 33.5383
PaTu 8902 GDSC1 1.5326 3.1246 1.486 31.1343
BxPC-3 GDSC1 1.5646 3.4505 1.4695 31.0367
SUIT-2 GDSC1 1.5865 3.4953 1.4848 30.8056
SW1990 GDSC1 1.9671 3.5798 1.8804 25.966
CFPAC-1 GDSC1 2.0071 4.5127 1.6663 27.1264
HPAC GDSC1 2.0223 3.2556 1.9901 24.9253
MIA PaCa-2 GDSC1 2.2403 3.1485 2.2288 22.0684
KP-4 GDSC1 2.3204 4.4014 2.0436 22.8357
Capan-2 GDSC1 2.5043 3.2892 2.4936 18.7635
Panc 10.05 GDSC1 2.551 3.5686 2.5121 18.3603
Hs 766T GDSC1 2.7674 3.5827 2.7415 15.5721
SU.86.86 GDSC1 2.9418 4.1744 2.7932 14.2177
Panc 04.03 GDSC1 3.0025 4.353 2.7981 13.852
HuP-T3 GDSC1 3.1552 3.9577 3.0893 10.9904
KP-3 GDSC1 3.243 4.3046 3.0745 10.6071
PL4 GDSC1 3.3147 4.0614 3.2345 9.0968
Panc 02.03 GDSC1 3.3331 3.9219 3.2919 8.6038
Capan-1 GDSC1 3.3579 4.2568 3.2155 8.9933
HPAF-II GDSC1 3.4228 4.5608 3.1615 9.0522
AsPC-1 GDSC1 3.4731 4.1386 3.3819 7.1991
YAPC GDSC1 4.2605 6.0442 3.186 5.5358
DAN-G GDSC1 6.2878 8.1303 3.3918 0.6634
Panc 08.13 GDSC1 6.553 8.2214 3.4606 0.3234
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-Mes1 GDSC1 2.8774 4.0632 2.7571 14.8265
NCI-H2052 GDSC1 3.0426 4.2795 2.8674 13.147
MPP 89 GDSC1 3.1324 4.2098 2.9886 11.8096
NCI-H28 GDSC1 3.3632 4.0699 3.2847 8.4804
NCI-H2452 GDSC1 4.6895 6.7223 3.1617 4.4907
MSTO-211H GDSC1 6.1367 8.2788 3.2712 1.2905
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU145 GDSC1 1.1738 2.8363 1.1385 35.5403
22Rv1 GDSC1 2.3926 3.5233 2.3492 20.3693
PC-3 GDSC1 2.5994 5.6574 1.8356 22.7769
VCaP GDSC1 3.1953 4.4589 2.9645 11.6448
LNCaP clone FGC GDSC1 3.2991 4.2848 3.142 9.8288
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 1.1258 3.2859 1.0254 36.5046
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHL-1 GDSC1 -0.065 2.6417 -0.1527 50.7517
A2058 GDSC1 0.5809 2.3814 0.556 42.8577
A-431 GDSC1 0.9632 2.7363 0.9266 38.1693
IGR-1 GDSC1 1.3137 2.3497 1.3105 33.599
A-375 GDSC1 1.3228 2.6397 1.3092 33.5496
Mel Ho GDSC1 1.4383 2.8448 1.4153 32.165
Hs 940.T GDSC1 1.5185 4.1562 1.2477 32.6561
SK-MEL-30 GDSC1 1.5273 3.8302 1.3458 32.0252
Mel JuSo GDSC1 1.6127 3.3454 1.5397 30.2999
HMV-II GDSC1 1.6153 3.087 1.5782 30.0419
LOX-IMVI GDSC1 1.8 3.0115 1.78 27.626
IST-MEL1 GDSC1 1.8339 4.2012 1.5783 28.7085
451Lu GDSC1 1.8836 3.7182 1.7607 27.2428
A101D GDSC1 1.9065 4.336 1.6155 28.0409
A-388 GDSC1 1.9728 3.671 1.8681 26.0123
WM793 GDSC1 1.9994 3.4533 1.9379 25.3998
IGR-37 GDSC1 2.0175 3.2061 1.9905 24.9522
SK-MEL-3 GDSC1 2.0597 2.9564 2.0527 24.2974
HT-144 GDSC1 2.261 3.0438 2.2556 21.7717
MZ-MEL-2 GDSC1 2.2902 3.7078 2.205 21.9223
COLO 679 GDSC1 2.3012 4.7156 1.9111 23.8443
G-361 GDSC1 2.3476 2.9831 2.3457 20.6671
GAK GDSC1 2.352 3.4502 2.3163 20.8271
DJM-1 GDSC1 2.448 5.8822 1.5815 25.2438
WM35 GDSC1 2.4559 3.6445 2.3969 19.6797
WM1552C GDSC1 2.458 4.1519 2.2734 20.4953
G-mel GDSC1 2.5129 4.3239 2.2784 20.1542
IPC-298 GDSC1 2.5138 4.613 2.1773 20.852
SH-4 GDSC1 2.6095 5.0924 2.0895 20.9612
VMRC-MELG GDSC1 2.6125 3.1573 2.6106 17.3554
WM278 GDSC1 2.6185 3.889 2.5212 17.9024
M14 GDSC1 2.6397 4.0198 2.51 17.8556
RPMI-7951 GDSC1 2.6881 3.5236 2.6647 16.547
MMAc-SF GDSC1 2.9121 3.6658 2.8845 13.7747
WM115 GDSC1 2.9486 4.2716 2.7684 14.353
LB2518-MEL GDSC1 2.9969 5.0281 2.5197 15.8963
MZ-MEL-7 GDSC1 3.1057 4.5902 2.8174 13.1708
Hs 938.T GDSC1 3.2559 3.8999 3.2129 9.5798
COLO 800 GDSC1 3.3072 5.0823 2.8109 12.2297
RVH-421 GDSC1 3.3995 3.8825 3.3726 7.6792
MeWo GDSC1 3.415 4.5761 3.1468 9.1995
SK-MEL-2 GDSC1 3.4294 3.8833 3.4048 7.2909
CP50-MEL-B GDSC1 3.4296 3.9274 3.3957 7.3502
UACC-257 GDSC1 3.4484 3.8621 3.4293 7.0177
LB373-MEL-D GDSC1 3.5517 3.8908 3.5356 5.7067
CP66-MEL GDSC1 3.5556 3.9973 3.5158 5.8164
SK-MEL-24 GDSC1 3.6332 4.6689 3.3261 6.812
SK-MEL-5 GDSC1 3.7253 4.3135 3.5806 4.4587
UACC-62 GDSC1 4.0059 4.8737 3.568 3.3853
SK-MEL-1 GDSC1 5.1865 6.6728 3.475 1.3498
SK-MEL-28 GDSC1 5.3314 10.277 1.89 11.9515
WT2-iPS GDSC1 5.648 6.8025 3.6245 0.2793
COLO 783 GDSC1 6.1359 7.6153 3.5194 0.3454
COLO 792 GDSC1 6.2496 8.1952 3.352 0.8395
COLO 829 GDSC1 6.6953 8.5315 3.4043 0.4071
EquiPSC Line K2 GDSC1 3.4049 7.8431 1.5625 20.8555
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 -1.4125 -0.1249 -1.4126 67.5691
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFH-ino GDSC1 -1.2087 -0.2327 -1.2087 65.0978
SK-LMS-1 GDSC1 -0.2613 2.4164 -0.3329 53.0277
Hs 633.T GDSC1 -0.1504 1.2521 -0.1523 51.8726
HT-1080 GDSC1 0.3987 2.5014 0.3553 45.1701
EW-8 GDSC1 0.6084 3.1503 0.4912 42.8791
VA-ES-BJ GDSC1 1.3012 3.8418 1.0964 34.9249
SW872 GDSC1 1.5162 2.9544 1.4874 31.2273
SW982 GDSC1 1.551 3.7388 1.3938 31.5866
G-401 GDSC1 1.5763 2.8244 1.5605 30.3954
G-402 GDSC1 1.8772 3.2473 1.8371 26.7887
SK-UT-1 GDSC1 2.1336 4.3759 1.8494 25.1979
RD GDSC1 2.1649 4.1712 1.9481 24.3609
Rh30 GDSC1 2.2247 3.3244 2.1967 22.3686
MES-SA GDSC1 2.3555 2.8411 2.3553 20.5575
A-204 GDSC1 2.5334 3.8846 2.4294 19.01
Rh41 GDSC1 3.0691 6.0191 2.1386 18.3533
KYM-1 GDSC1 3.1548 3.9407 3.0931 10.9673
RKN GDSC1 3.3332 3.7974 3.3159 8.4456
GCT GDSC1 3.4499 4.0517 3.3847 7.308
TE 441.T GDSC1 3.5341 3.9443 3.5056 6.0092
STS-0421 GDSC1 5.2868 8.9292 2.5077 7.7676
SW684 GDSC1 5.7054 7.0103 3.5718 0.4086
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MKN28 GDSC1 -0.994 1.1434 -1.0054 61.955
HGC-27 GDSC1 -0.4489 1.3446 -0.4559 55.5243
AGS GDSC1 0.1562 2.4447 0.1055 48.1295
MKN45 GDSC1 1.1344 6.4912 -0.0378 40.5184
IM95 GDSC1 1.4791 2.9124 1.4523 31.6791
RF-48 GDSC1 1.701 4.6718 1.2801 31.3249
ECC10 GDSC1 1.7519 3.8335 1.59 29.1292
MKN1 GDSC1 2.0036 4.73 1.5859 27.6622
GCIY GDSC1 2.1956 6.3259 1.1267 29.3183
NUGC-3 GDSC1 2.2847 4.8279 1.8511 24.3404
Fu97 GDSC1 2.4922 3.113 2.4895 18.8641
RERF-GC-1B GDSC1 2.6064 3.6892 2.5513 17.7739
SNU-1 GDSC1 2.853 4.597 2.5464 16.4358
NUGC-4 GDSC1 2.8645 3.9271 2.7799 14.7454
23132/87 GDSC1 3.0657 4.4318 2.8368 13.2405
TMK-1 GDSC1 3.1511 4.4485 2.9217 12.1835
MKN7 GDSC1 3.328 4.1307 3.2271 9.074
TGBC11TKB GDSC1 3.3534 4.0785 3.2715 8.6263
OCUM-1 GDSC1 3.5624 4.322 3.4078 6.5439
NCI-N87 GDSC1 3.61 4.7456 3.2674 7.3649
HSC-39 GDSC1 4.7374 6.3313 3.3765 2.8006
SNU-5 GDSC1 5.3526 6.9332 3.4485 1.2766
SCH GDSC1 5.7374 6.948 3.6064 0.2881
SNU-16 GDSC1 5.8351 6.9492 3.6418 0.1677
SNG-M GDSC1 1.5846 2.9529 1.5593 30.3511
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC1 -0.5952 0.2806 -0.5952 57.4389
TT2609-C02 GDSC1 -0.2816 1.3681 -0.2866 53.4853
8505C GDSC1 0.3501 1.9736 0.3396 45.6637
CAL-62 GDSC1 0.5467 3.4952 0.3562 43.8416
8305C GDSC1 1.1479 3.4956 1.0092 36.4387
ML-1 [Human leukemia] GDSC1 1.446 2.2386 1.4454 31.9284
ASH-3 GDSC1 1.5261 2.6032 1.5198 30.963
CGTH-W-1 GDSC1 1.8971 4.9977 1.3721 29.6031
KMH-2 GDSC1 2.0587 3.8242 1.9267 25.1192
B-CPAP GDSC1 2.492 4.0284 2.3464 19.8069
HTC-C3 GDSC1 2.6737 4.0226 2.5463 17.4159
BHT-101 GDSC1 3.1643 3.8721 3.1194 10.7365
K5 GDSC1 3.1838 4.2372 3.0348 11.2057
WRO GDSC1 3.5165 4.2057 3.4047 6.8048
TT GDSC1 3.5575 4.0575 3.5003 5.9115
FTC-133 GDSC1 3.8374 4.6178 3.547 4.2086
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-3 GDSC1 -0.4839 2.9478 -0.6515 55.17
Ca9-22 GDSC1 0.1466 2.93 0.031 48.3176
BHY GDSC1 0.2065 2.3702 0.1656 47.5063
OSC-20 GDSC1 0.4551 2.4465 0.4196 44.4527
BB30-HNC GDSC1 0.7536 3.8104 0.507 41.6276
PCI-06A GDSC1 0.7591 2.9406 0.686 40.8738
JHU-011 GDSC1 0.919 2.7041 0.8832 38.7152
KON GDSC1 1.0919 2.7851 1.0573 36.5569
CAL-27 GDSC1 1.2313 3.1546 1.1603 35.0338
PCI-04B GDSC1 1.2858 3.0954 1.2269 34.2858
SCC-25 GDSC1 1.3142 4.1164 1.0363 35.1581
HSC-2 GDSC1 1.4207 3.5119 1.3018 32.9676
JHU-029 GDSC1 1.4326 3.6874 1.2769 33.0385
KOSC-2 GDSC1 1.5493 3.7647 1.3858 31.6456
NCI-H3118 GDSC1 1.5586 2.9878 1.5288 30.7046
OSC-19 GDSC1 1.7138 3.5407 1.6137 29.211
CAL-33 GDSC1 1.8176 6.0189 0.8731 32.7908
SAS GDSC1 2.0271 6.6388 0.8154 31.8682
HO-1-u-1 GDSC1 2.1912 4.2734 1.9451 24.2311
BICR 31 GDSC1 2.3198 2.9288 2.3186 21.01
HSC-4 GDSC1 2.3474 2.8998 2.3467 20.6619
SCC-15 GDSC1 2.3711 5.1709 1.8069 24.1679
SCC-4 GDSC1 2.3977 4.8424 1.9661 22.9419
PCI-15A GDSC1 2.4599 3.1258 2.4562 19.2747
BICR 78 GDSC1 2.4856 3.9933 2.3492 19.8242
Detroit 562 GDSC1 2.5996 4.186 2.4172 18.716
BICR 10 GDSC1 2.6236 3.2135 2.6205 17.2242
JHU-022 GDSC1 2.8049 3.9711 2.7035 15.6027
HO-1-N-1 GDSC1 3.095 5.8491 2.2441 17.4621
FaDu GDSC1 3.1247 4.247 2.9675 11.999
PE/CA-PJ15 GDSC1 3.1496 3.868 3.1044 10.9225
SCC-9 GDSC1 3.1538 9.4028 0.5646 27.5587
LB771-HNC GDSC1 3.2941 6.3928 2.1742 17.0777
BICR 22 GDSC1 3.3989 4.1689 3.2911 8.239
PCI-38 GDSC1 3.5316 4.1842 3.4289 6.5519
BB49-HNC GDSC1 3.5514 4.4688 3.334 7.141
DOK GDSC1 3.5648 5.5892 2.8188 11.018
UPCI-SCC-090 GDSC1 3.5887 4.5247 3.3475 6.8591
SAT [Human HNSCC] GDSC1 3.7392 6.7931 2.3806 13.6823
PCI-30 GDSC1 3.7748 4.6215 3.4862 4.949
SKN-3 GDSC1 6.9415 8.7125 3.4309 0.2586
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
639V GDSC1 -2.0199 -0.7756 -2.0199 75.0371
SW1710 GDSC1 -0.5649 1.3082 -0.573 56.9242
5637 GDSC1 -0.0192 2.0348 -0.0442 50.2329
J82 GDSC1 0.2119 2.3289 0.1749 47.4338
RT-112 GDSC1 0.2655 2.7308 0.1878 46.8651
BFTC-905 GDSC1 0.9542 1.9882 0.9527 38.0818
647V GDSC1 2.1755 3.6419 2.094 23.3303
TCCSUP GDSC1 2.2226 3.1714 2.2087 22.3053
CAL-29 GDSC1 2.4605 3.071 2.4583 19.2571
HT-1197 GDSC1 2.5155 3.1516 2.5121 18.5771
T24 GDSC1 3.302 4.0287 3.2302 9.198
RT-4 GDSC1 3.3231 4.1987 3.1988 9.2982
HT-1376 GDSC1 3.3946 5.0283 2.9229 10.9752
UM-UC-3 GDSC1 4.1662 11.1817 0.5467 23.6606
KU-19-19 GDSC1 5.7056 6.9314 3.6003 0.3204
SW780 GDSC1 6.0185 7.5397 3.5016 0.4566
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-39 GDSC1 0.3277 2.7862 0.2467 46.1298
SW962 GDSC1 0.4496 3.647 0.2157 45.0652
DoTc2 4510 GDSC1 1.0925 2.227 1.0888 36.367
HeLa GDSC1 1.1426 2.9014 1.0987 35.9796
PA-1 GDSC1 1.1759 3.0453 1.1165 35.6552
NCC-IT GDSC1 1.2596 3.5747 1.1138 35.1084
NEC8 GDSC1 1.5994 3.2362 1.5423 30.3665
ME-180 GDSC1 1.6666 3.4989 1.5708 29.7717
SW954 GDSC1 1.6707 4.8824 1.1722 32.1221
C-33 A GDSC1 1.9105 3.7721 1.7776 26.9723
OMC-1 [Human cervical carcinoma] GDSC1 2.217 4.1687 2.0056 23.6765
HEC-1 GDSC1 2.2553 4.0335 2.0867 22.9132
KGN GDSC1 2.2756 3.942 2.1336 22.4819
BPH-1 GDSC1 2.3631 3.5061 2.3202 20.7351
SW756 GDSC1 2.3804 6.7196 1.1329 28.2962
MS751 GDSC1 2.4692 3.6591 2.4086 19.5247
SiSo GDSC1 2.5207 4.1467 2.3433 19.6652
HT-3 GDSC1 2.8493 4.4847 2.585 16.1805
Ca Ski GDSC1 2.8994 5.7567 2.0938 19.4801
NT2-D1 GDSC1 3.0128 4.7282 2.6633 14.7656
SKN GDSC1 3.0554 4.2584 2.8885 12.9299
C-4-I GDSC1 3.1297 5.2912 2.5375 15.1197
JEG-3 GDSC1 3.3131 4.127 3.2122 9.2596
LB831-BLC GDSC1 3.4018 4.4945 3.1678 9.1103
OVMIU GDSC1 3.5213 4.6819 3.2085 8.2243
SKG-IIIa GDSC1 3.5274 3.9975 3.4849 6.1865
JAR GDSC1 5.5047 7.2941 3.3737 1.4898
SiHa GDSC1 5.7557 7.1546 3.5388 0.4895
DSH1 GDSC1 6.5144 8.4539 3.363 0.6213
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug

References

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2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
3 From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitors. Cancer Res. 2004 Jun 15;64(12):4309-18. doi: 10.1158/0008-5472.CAN-03-4063.