Details of the Drug

General Information of Drug (ID: DM6P3Z8)

Drug Name

2'-5'dideoxyuridine

Synonyms

2',5'-Dideoxyuridine; 2'-5'dideoxyuridine; 35959-50-3; AC1L9G4G; Uridine, 2',5'-dideoxy-; SCHEMBL2919639; CTK1C1122; DTXSID00332151; FDCFKLBIAIKUKB-GKROBHDKSA-N; ZINC3870698; DB03274

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski): 0

Molecular Weight (mw)

212.2

Logarithm of the Partition Coefficient (xlogp)

-1.1

Rotatable Bond Count (rotbonds)

1

Hydrogen Bond Donor Count (hbonddonor)

2

Hydrogen Bond Acceptor Count (hbondacc)

4

Chemical Identifiers

Formula: C9H12N2O4
IUPAC Name: 1-[(2R,4S,5R)-4-hydroxy-5-methyloxolan-2-yl]pyrimidine-2,4-dione
Canonical SMILES: C[C@@H]1[C@H](C[C@@H](O1)N2C=CC(=O)NC2=O)O
InChI: InChI=1S/C9H12N2O4/c1-5-6(12)4-8(15-5)11-3-2-7(13)10-9(11)14/h2-3,5-6,8,12H,4H2,1H3,(H,10,13,14)/t5-,6+,8-/m1/s1
InChIKey: FDCFKLBIAIKUKB-GKROBHDKSA-N

Cross-matching ID

PubChem CID: 444320
CAS Number: 35959-50-3
DrugBank ID: DB03274
TTD ID: D08STR

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Candida Thymidylate synthase (Candi TMP1)	TTU6BFZ	TYSY_CANAL	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41.