Details of the Drug

General Information of Drug (ID: DM6XJ9S)

Drug Name
SB-743921
Synonyms N-[1-(3-benzyl-7-chloro-4-oxo-quinazolin-2-yl)propyl]-4-bromo-N-(3-dimethylaminopropyl)benzamide
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 2 [1]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski):
1		 Molecular Weight 553.5
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 9
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 4
Chemical Identifiers
Formula
C31H34Cl2N2O3
IUPAC Name
N-(3-aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxochromen-2-yl)-2-methylpropyl]-4-methylbenzamide;hydrochloride
Canonical SMILES
CC1=CC=C(C=C1)C(=O)N(CCCN)[C@@H](C2=C(C(=O)C3=C(O2)C=C(C=C3)Cl)CC4=CC=CC=C4)C(C)C.Cl
InChI
InChI=1S/C31H33ClN2O3.ClH/c1-20(2)28(34(17-7-16-33)31(36)23-12-10-21(3)11-13-23)30-26(18-22-8-5-4-6-9-22)29(35)25-15-14-24(32)19-27(25)37-30;/h4-6,8-15,19-20,28H,7,16-18,33H2,1-3H3;1H/t28-;/m1./s1
InChIKey
MLMZVWABFOLFGV-LNLSOMNWSA-N
Cross-matching ID
PubChem CID
49867937
CAS Number
940929-33-9
UNII
24DSZ1VN92
DrugBank ID
DB05546
TTD ID
D0U4EU

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Kinesin-like protein KIF11 (KIF11) TTTRP0H KIF11_HUMAN Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Kinesin-like protein KIF11 (KIF11) DTT KIF11 5.72E-26 -1.17 -1.31
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 154 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 -11.4857 -4.6859 -11.5152 90.255
JK1 CTRP2 -9.8117 -1.5196 -9.9562 82.5402
JM1 CTRP2 -11.7801 -7.9197 -11.7803 96.4356
Karpas-422 CTRP2 -16.0095 -4.2669 -16.2135 90.727
KMS-18 CTRP2 -15.9111 -4.4748 -16.0936 91.01
MOLP-8 CTRP2 -15.8911 3.5366 -17.4098 80.9358
MOLM-6 CTRP2 -15.5859 2.2501 -16.7732 82.1575
THP-1 CTRP2 -15.3627 -2.3971 -15.723 87.9718
M-07e CTRP2 -15.3476 -4.6891 -15.4904 91.2693
SET-2 CTRP2 -15.2559 -1.7072 -15.6981 86.9773
RL CTRP2 -15.1456 1.3108 -16.0939 83.0016
SUP-HD1 CTRP2 -15.083 3.5607 -16.5345 80.3726
U266B1 CTRP2 -14.881 -2.7213 -15.1753 88.2888
Kasumi-2 CTRP2 -14.6791 -4.6541 -14.7985 91.1452
LP-1 CTRP2 -14.4212 -0.383 -15.0012 84.7769
Daudi CTRP2 -14.298 -3.4854 -14.4876 89.2653
CA46 CTRP2 -14.122 -1.3644 -14.5348 86.0056
MHH-CALL-4 CTRP2 -14.049 3.602 -15.4173 79.5467
Mono-Mac-1 CTRP2 -13.7795 6.4705 -15.9052 76.3281
NU-DHL-1 CTRP2 -13.7722 0.583 -14.4673 83.0652
TALL-1 [Human adult T-ALL] CTRP2 -13.7612 4.8901 -15.4367 77.8987
Ri-1 CTRP2 -13.5774 -0.8978 -14.0181 85.0258
KMS-28BM CTRP2 -13.4477 2.0895 -14.4133 80.8572
MOTN-1 CTRP2 -13.3932 0.5924 -14.0599 82.7838
SUP-T11 CTRP2 -13.383 7.7982 -15.8802 74.7192
Karpas-299 CTRP2 -12.8381 -0.9328 -13.2236 84.6005
MJ CTRP2 -12.725 -2.5087 -12.9242 87.0466
Hs 611.T CTRP2 -12.695 -0.5523 -13.124 83.9167
AML-193 CTRP2 -12.5234 5.2607 -14.1874 76.3002
Raji CTRP2 -12.4132 6.6643 -14.4734 74.7542
HDLM-2 CTRP2 -12.3075 2.5425 -13.2724 79.2471
PF-382 CTRP2 -12.2596 -0.6756 -12.6413 83.7651
DB CTRP2 -12.2566 -2.2059 -12.4603 86.2481
KHM-1B CTRP2 -12.0098 -2.9005 -12.1432 87.281
KYO-1 CTRP2 -11.9379 0.2249 -12.4304 82.1019
EJM CTRP2 -11.9053 -5.1291 -11.9305 91.3039
EB1 CTRP2 -11.8913 3.0489 -12.9339 78.1678
Namalwa CTRP2 -11.8704 -9.9044 -11.8704 99.3298
KMS-20 CTRP2 -11.8514 -0.4753 -12.2331 83.0986
697 CTRP2 -11.8128 -10.3474 -11.8128 99.7298
JeKo-1 CTRP2 -11.8076 -10.1749 -11.8076 99.6014
K-562 CTRP2 -11.7475 -4.1002 -11.803 89.2969
EoL-1 CTRP2 -11.7348 -10.0609 -11.7348 99.5252
SUP-B15 CTRP2 -11.7183 -9.7301 -11.7183 99.1881
KMS-11 CTRP2 -11.6253 -5.6625 -11.6369 92.2027
OCI-M1 CTRP2 -11.6003 0.0965 -12.048 81.9681
MOLT-16 CTRP2 -11.5878 -10.1411 -11.5878 99.6416
JJN-3 CTRP2 -11.5678 -6.3688 -11.5721 93.5375
HPB-ALL CTRP2 -11.5444 -3.439 -11.6257 87.9375
RS4;11 CTRP2 -11.5289 -8.7841 -11.529 97.9057
ST486 CTRP2 -11.5062 -10.14 -11.5062 99.6661
Granta-519 CTRP2 -11.4997 -6.3121 -11.504 93.4055
KO52 CTRP2 -11.4947 -3.8305 -11.5551 88.6335
Reh CTRP2 -11.4924 -9.6418 -11.4924 99.1515
OCI-AML-3 CTRP2 -11.4666 -10.0746 -11.4666 99.6225
BDCM CTRP2 -11.3875 -7.1083 -11.3883 94.8995
OCI-Ly19 CTRP2 -11.3621 -8.7321 -11.3621 97.8379
CML-T1 CTRP2 -11.3498 0.638 -11.8653 80.882
A4/Fukuda CTRP2 -11.3358 -5.7808 -11.3435 92.3037
Mino CTRP2 -11.3307 -10.0992 -11.3307 99.6865
KMS-34 CTRP2 -11.274 -9.7872 -11.274 99.3909
HuNS1 CTRP2 -11.2671 -4.7052 -11.2923 90.1596
GA-10 CTRP2 -11.252 -9.5997 -11.252 99.1674
Pfeiffer CTRP2 -11.2394 -9.3574 -11.2394 98.837
RPMI-6666 CTRP2 -11.2382 -8.6798 -11.2382 97.757
MOLP-2 CTRP2 -11.2285 24.5584 -20.2162 62.9298
KMS-27 CTRP2 -11.209 -9.0095 -11.209 98.3079
OCI-AML-5 CTRP2 -11.1903 -9.9546 -11.1903 99.5977
KMS-21-BM CTRP2 -11.0815 -5.0211 -11.0974 90.6593
BV-173 CTRP2 -11.0769 -6.7339 -11.078 94.0639
BL-70 CTRP2 -11.0346 -9.829 -11.0346 99.5129
SEM CTRP2 -10.9268 -9.3453 -10.9268 98.8799
OPM-2 CTRP2 -10.9198 -4.7626 -10.9386 90.0308
SIG-M5 CTRP2 -10.8904 -6.6037 -10.8915 93.7129
PL21 CTRP2 -10.825 -8.8743 -10.825 98.0954
KMS-12-BM CTRP2 -10.7928 -8.6906 -10.7928 97.7591
KMS-26 CTRP2 -10.785 -9.082 -10.785 98.46
MM1.S CTRP2 -10.7789 -1.8588 -10.9404 84.3694
Ci-1 CTRP2 -10.7767 -4.0532 -10.8113 88.5078
GDM-1 CTRP2 -10.758 8.4483 -13.2378 71.0581
OCI-AML-2 CTRP2 -10.7487 -9.3447 -10.7487 98.9038
HH [Human lymphoma] CTRP2 -10.6622 9.7469 -13.5774 69.8528
RCH-ACV CTRP2 -10.622 -6.8359 -10.6224 94.0233
HuT 78 CTRP2 -10.61 -0.1512 -10.9524 81.2538
P31/FUJ CTRP2 -10.5531 -8.891 -10.5531 98.0926
MOLT-13 CTRP2 -10.5444 -7.549 -10.5445 95.4292
SU-DHL-10 CTRP2 -10.5072 -6.1811 -10.5086 92.5928
L-363 CTRP2 -10.4708 -4.3496 -10.492 88.8119
MOLM-16 CTRP2 -10.4471 -5.5446 -10.4514 91.2279
Peer CTRP2 -10.2899 -7.4531 -10.29 95.0501
MOLM-13 CTRP2 -10.2545 -7.5536 -10.2546 95.229
HD-MY-Z CTRP2 -10.1917 20.1987 -17.2408 63.3195
NU-DUL-1 CTRP2 -10.1662 -8.7912 -10.1662 97.7246
RPMI-8226 CTRP2 -10.1276 -7.5371 -10.1276 95.0762
TF-1 CTRP2 -10.0798 3.92 -11.1682 74.7351
RPMI-8402 CTRP2 -10.0238 -8.1773 -10.0238 96.3092
CMK CTRP2 -10.0226 -7.7836 -10.0226 95.481
KE-37 CTRP2 -9.992 -8.5942 -9.992 97.1486
OCI-Ly3 CTRP2 -9.9428 -6.0375 -9.9436 91.7181
L-428 CTRP2 -9.9045 2.2797 -10.6066 76.6009
MV4-11 CTRP2 -9.7544 3.0131 -10.6001 75.3758
NALM-6 CTRP2 -9.6648 -8.6333 -9.6648 96.6715
P12-Ichikawa CTRP2 -9.6591 -8.7927 -9.6591 96.9636
SU-DHL-6 CTRP2 -9.6521 -7.7245 -9.6521 94.811
NCO2 CTRP2 -9.5522 0.0511 -9.8516 79.4211
NB4 CTRP2 -9.5001 -9.1048 -9.5001 96.8105
SU-DHL-8 CTRP2 -9.3848 -8.0395 -9.3848 94.7945
SU-DHL-4 CTRP2 -9.3695 -8.715 -9.3695 95.7761
NOMO-1 CTRP2 -9.3682 -8.8648 -9.3682 95.9101
DEL CTRP2 -9.3331 -8.8846 -9.3331 95.7252
AMO1 CTRP2 -9.3119 -8.1919 -9.3119 94.8127
U-937 CTRP2 -9.3044 -8.6435 -9.3044 95.3831
MC116 CTRP2 -9.2571 -8.7644 -9.2571 95.2166
HL-60 CTRP2 -9.1239 -5.5275 -9.1245 89.2825
ALL-SIL CTRP2 -9.1231 -7.3704 -9.1231 92.8
JVM-3 CTRP2 -8.9533 -7.199 -8.9533 91.9361
SKM-1 CTRP2 -8.8942 -7.5525 -8.8942 92.212
WSU-DLCL2 CTRP2 -8.7998 -8.075 -8.7998 92.1692
JURL-MK1 CTRP2 -8.6641 -7.4961 -8.6641 91.0346
Jurkat CTRP2 -8.4943 -7.4897 -8.4943 90.0772
Kasumi-1 CTRP2 -8.4272 -6.1968 -8.4272 88.407
HT CTRP2 -8.4008 -1.9335 -8.4613 80.7124
KE-97 CTRP2 -8.3843 -7.5649 -8.3843 89.4283
EHEB CTRP2 -8.2449 4.664 -9.3564 70.5967
EM-2 CTRP2 -7.9742 -2.0982 -8.015 79.9452
OCI-Ly10 CTRP2 -7.9529 5.7589 -9.3413 68.8205
DoHH2 CTRP2 -7.9248 -6.898 -7.9248 86.3632
JVM-2 CTRP2 -7.7605 2.7124 -8.3693 71.8938
KCL-22 CTRP2 -7.753 -6.6478 -7.753 85.2172
BCP-1 CTRP2 -7.5955 -2.6596 -7.6116 79.7917
NCI-H929 CTRP2 -7.5552 -1.0475 -7.6382 76.9807
F-36P CTRP2 -7.5469 -2.0711 -7.5786 78.6572
KM-H2 CTRP2 -7.4051 -6.3689 -7.4051 82.9266
SUP-T1 CTRP2 -6.8329 4.6499 -7.8121 67.3042
SR CTRP2 -6.7275 7.0194 -8.3916 64.8517
LAMA-84 CTRP2 -6.4057 2.3718 -6.8364 68.6079
HEL 92.1.7 CTRP2 -4.9324 34.5908 -18.6894 53.3812
Ku812 CTRP2 -4.5367 10.1082 -7.1274 57.0145
Ki-JK CTRP2 -3.8634 3.2089 -4.2444 57.6513
SK-MM-2 CTRP2 -2.4508 7.127 -3.7857 49.9539
HEL CTRP2 -1.4569 8.577 -3.2524 45.4891
L-540 CTRP2 -1.2069 7.0427 -2.4118 43.6652
SU-DHL-1 CTRP2 -0.9275 4.1418 -1.2505 40.5967
DND-41 CTRP2 -0.0585 102.2623 -47.8798 48.7134
Mono-Mac-6 CTRP2 -0.0278 92.7932 -43.1254 48.5644
MHH-CALL-3 CTRP2 0.0747 58.748 -26.0536 47.6436
ME1 CTRP2 0.1532 27.0203 -10.2455 44.8353
P3HR-1 CTRP2 1.8349 44.4739 -17.405 44.5554
L-1236 CTRP2 3.5033 5.2152 3.313 10.9396
Karpas-620 CTRP2 4.1173 5.3497 3.9355 6.831
REC-1 CTRP2 4.4613 5.135 4.3812 4.1686
KMM-1 CTRP2 4.5388 6.8811 3.6768 6.8049
BL-41 CTRP2 4.6875 17.8606 -1.6635 25.5674
Toledo CTRP2 6.347 16.9343 0.147 17.1355
⏷ Show the Full List of 154 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 -14.4222 -1.4273 -14.8466 86.2401
TE8 CTRP2 -8.5539 10.345 -11.5186 66.1075
TE-11 CTRP2 -15.0454 -3.8129 -15.2425 89.9352
EC-GI-10 CTRP2 -14.868 1.9779 -15.9327 82.0274
OE21 CTRP2 -12.3288 8.8364 -15.0717 72.6923
TE-4 CTRP2 -10.9281 5.25 -12.4435 74.4068
KYSE-70 CTRP2 -8.7159 21.3216 -16.2166 60.9828
KYSE-180 CTRP2 -7.1006 1.7431 -7.4764 71.4863
TE-9 CTRP2 -6.7886 -2.7974 -6.7939 76.9104
TE-6 CTRP2 -6.6121 18.4175 -13.1923 57.7534
TE-14 CTRP2 -6.2622 4.0541 -7.0392 66.3045
KYSE-410 CTRP2 -5.5645 9.8136 -8.1131 60.0093
TE-10 CTRP2 -5.118 0.4519 -5.2085 65.6804
TE-5 CTRP2 -4.2028 19.3538 -10.7645 53.8966
KYSE-510 CTRP2 -2.9578 10.2621 -5.5123 51.833
KYSE-450 CTRP2 -0.8695 18.1726 -6.9234 45.687
KYSE-520 CTRP2 0.2066 15.6727 -4.693 41.4109
COLO 680N CTRP2 0.8857 6.6717 -0.0232 30.711
TE-1 CTRP2 0.9029 4.8814 0.5682 28.7279
KYSE-140 CTRP2 1.1701 29.2718 -10.4324 43.1421
KYSE-150 CTRP2 2.1913 25.3702 -7.5842 39.5671
OE33 CTRP2 3.1336 13.9526 -1.0876 27.4995
OE19 CTRP2 3.2118 6.1506 2.6623 14.2257
KYSE-30 CTRP2 7.1444 20.8882 -1.2027 19.8551
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 -6.0744 30.7627 -17.9481 55.281
DAN-G CTRP2 -13.2077 3.2745 -14.4207 79.2049
MIA PaCa-2 CTRP2 -11.1442 6.8079 -13.134 73.0853
Panc 03.27 CTRP2 -10.7574 14.9074 -15.6253 66.5456
L3.3 CTRP2 -10.4278 11.6423 -14.0107 68.1308
PaTu 8988t CTRP2 -10.3124 5.5918 -11.8675 73.1734
HuP-T4 CTRP2 -8.193 13.0444 -12.1663 63.7764
KP-4 CTRP2 -5.8835 6.8149 -7.4081 62.7734
KP-3 CTRP2 -5.2901 11.4664 -8.4624 58.5155
BxPC-3 CTRP2 -5.0977 2.7618 -5.4947 63.4876
KP-2 CTRP2 -5.0361 499.7865 -250.7764 50.2802
AsPC-1 CTRP2 -3.3927 21.8512 -11.1219 51.9578
PaTu 8988s CTRP2 -3.1902 18.1713 -9.2098 51.7872
Panc 08.13 CTRP2 -2.0102 9.6918 -4.2814 48.1779
Panc 10.05 CTRP2 -1.5802 23.202 -10.0105 48.1181
PSN1 CTRP2 -0.9466 12.7733 -4.4985 44.5948
QGP-1 CTRP2 -0.4288 32.3157 -13.3838 46.6666
SW1990 CTRP2 -0.2611 82.8866 -38.3818 48.552
HPAC CTRP2 -0.0794 4.2863 -0.3601 35.0126
HuP-T3 CTRP2 0.1195 13.4228 -3.7241 40.6278
SNU-213 CTRP2 1.4441 14.3666 -2.8755 35.6982
TCC-Pan2 CTRP2 1.6647 31.3167 -11.0047 42.6021
SU.86.86 CTRP2 1.8719 13.8665 -2.2262 33.353
Panc 05.04 CTRP2 1.9901 21.5999 -5.8988 38.4206
PaTu 8902 CTRP2 2.3324 3.8385 2.3067 18.1539
PK-45H CTRP2 2.3539 10.1333 0.016 26.2592
SNU-410 CTRP2 2.4722 5.8834 1.9705 18.9386
Hs 766T CTRP2 2.5043 4.1874 2.4506 17.1044
CFPAC-1 CTRP2 3.0074 15.1101 -1.7727 29.519
SUIT-2 CTRP2 3.6554 10.6849 0.9968 19.5992
HPAF-II CTRP2 3.882 23.3745 -5.1065 33.7027
Capan-1 CTRP2 4.4733 18.5292 -2.1796 27.2439
Panc 04.03 CTRP2 4.5123 16.4578 -1.1116 24.4799
PK-59 CTRP2 5.6665 19.0151 -1.4295 23.0593
Capan-2 CTRP2 5.8447 17.4805 -0.5199 20.1507
YAPC CTRP2 5.9017 20.6877 -2.0748 24.2575
Panc 02.03 CTRP2 9.6171 25.8496 -1.8378 17.8461
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 -7.4455 9.1699 -9.9 64.8251
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHP-126 CTRP2 -13.7525 2.1759 -14.7632 80.9926
NB1 CTRP2 -13.6069 -3.6846 -13.7499 89.3739
CHP-212 CTRP2 -13.5413 -3.7095 -13.6797 89.3931
NH-6 CTRP2 -13.4485 3.7972 -14.8111 78.8152
KP-N-SI9s CTRP2 -12.6777 5.8036 -14.5088 75.8978
SK-N-AS CTRP2 -11.4099 6.6832 -13.3856 73.549
SK-N-FI CTRP2 -11.1606 -1.5142 -11.3743 84.1571
IMR-32 CTRP2 -10.9456 -9.7863 -10.9456 99.49
Kelly CTRP2 -9.4656 -8.3334 -9.4656 95.5648
SK-N-DZ CTRP2 -8.4909 1.9819 -9.0178 74.5018
MHH-NB-11 CTRP2 -7.3839 -6.462 -7.3839 82.7929
SK-N-SH CTRP2 -6.577 1.427 -6.8652 70.333
SiMa CTRP2 -6.5509 -1.9183 -6.5681 74.7697
SK-N-BE(2) CTRP2 -5.664 7.3857 -7.356 61.7404
KP-N-YN CTRP2 2.3093 9.4333 0.2966 25.4654
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 -8.2009 1.4551 -8.6126 74.6443
SNU-1079 CTRP2 -3.5754 6.438 -4.7771 55.0135
SNU-245 CTRP2 -2.5649 9.8518 -4.9322 50.4035
SNU-308 CTRP2 -0.2322 15.5624 -5.0694 42.9282
SNU-869 CTRP2 -0.1298 28.9979 -11.4772 45.7281
SNU-1196 CTRP2 2.5123 4.8469 2.3324 17.4938
HuH-28 CTRP2 2.9479 4.2501 2.9144 14.0805
HuCC-T1 CTRP2 2.9736 6.5114 2.2651 16.41
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SaOS-2 CTRP2 -15.0922 -0.6829 -15.6741 85.5186
HOS CTRP2 -15.0678 3.9641 -16.6193 79.9284
TC71 CTRP2 -11.6971 -3.1912 -11.7983 87.5902
RD-ES CTRP2 -11.5422 -5.4821 -11.5556 91.8193
A-673 CTRP2 -11.2966 -9.0857 -11.2966 98.4165
SK-N-MC CTRP2 -10.8416 -8.4244 -10.8416 97.2714
SK-ES-1 CTRP2 -9.5734 -5.9836 -9.5739 91.0716
MHH-ES-1 CTRP2 -9.2225 -7.9235 -9.2225 94.0624
SJSA-1 CTRP2 -7.5353 15.9667 -12.6753 61.2109
G-292 clone A141B1 CTRP2 -7.2089 25.6619 -16.6663 57.7117
SW1353 CTRP2 -6.7124 27.7165 -17.132 56.6184
MG-63 CTRP2 -5.2074 35.128 -19.2097 53.6828
U2OS CTRP2 -4.2974 4.9287 -5.1192 58.6588
Hs 888.T CTRP2 0.5008 44.4487 -18.5615 46.3477
CAL-78 CTRP2 0.7376 50.816 -21.5227 46.5288
Hs 822.T CTRP2 3.1997 3.9108 3.1975 12.2969
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 72 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-468 CTRP2 -15.0088 -3.4428 -15.237 89.3809
SK-BR-3 CTRP2 -14.7965 4.0924 -16.3562 79.5925
MDA-MB-157 CTRP2 -12.4317 11.6952 -16.1829 70.6046
AU565 CTRP2 -12.1119 8.3166 -17.2938 64.6013
CAL-148 CTRP2 -10.6964 -7.5693 -10.6965 95.5527
Hs 578T CTRP2 -10.5393 4.1191 -11.7191 75.1657
HCC1806 CTRP2 -10.426 10.5091 -13.5933 68.9391
HCC38 CTRP2 -10.3302 16.2404 -15.7146 65.278
BT-474 CTRP2 -10.2186 11.4633 -13.7196 67.9597
HCC1954 CTRP2 -10.0767 1.8069 -10.6999 77.5279
HCC1395 CTRP2 -9.9967 4.2643 -11.1641 74.1943
CAL-85-1 CTRP2 -9.6985 9.3728 -12.4049 68.7364
BT-20 CTRP2 -9.4534 34.1825 -22.8563 58.6137
DU4475 CTRP2 -9.3114 -3.7373 -9.3291 86.024
HCC1143 CTRP2 -8.9196 17.0233 -14.5639 62.942
CAL-51 CTRP2 -8.5931 15.6268 -13.638 63.0942
HMC-1-8 CTRP2 -6.1209 5.2423 -7.1952 64.7472
BT-549 CTRP2 -5.3943 20.8873 -12.6595 55.9111
MDA-MB-453 CTRP2 -4.9534 15.387 -9.7516 56.353
HCC1500 CTRP2 -4.4317 7.9609 -6.2184 57.5898
CAMA-1 CTRP2 -3.7108 71.1555 -35.5637 52.018
HCC2218 CTRP2 -3.38 18.7899 -9.6838 52.1769
JIMT-1 CTRP2 -2.6386 22.0988 -10.503 50.3811
UACC-812 CTRP2 -1.9618 35.3549 -16.2835 49.2773
HCC202 CTRP2 -0.9887 13.8631 -5.0335 45.0682
ZR-75-1 CTRP2 -0.4715 50.4996 -22.4291 47.8761
HCC1569 CTRP2 -0.0874 11.2694 -2.9533 40.2924
MCF-7 CTRP2 -0.0727 55.5493 -24.5897 49.136
ZR-75-30 CTRP2 0.1675 30.5687 -11.9796 45.3773
MDA-MB-231 CTRP2 0.386 38.1773 -15.5482 45.9356
T-47D CTRP2 0.6031 14.2443 -3.6316 39.13
Hs 578Bst CTRP2 0.8336 9.2242 -6.2416 14.0713
HCC1419 CTRP2 1.0787 12.6573 -2.4197 35.9018
MDA-MB-361 CTRP2 1.7979 33.2418 -11.8435 42.7762
HDQ-P1 CTRP2 2.1164 18.2091 -4.1132 35.9688
KPL-1 CTRP2 2.1404 3.3326 2.1353 19.3638
HCC1937 CTRP2 2.3613 3.9287 2.3288 17.9846
HCC1428 CTRP2 4.4345 25.3423 -5.6172 33.3906
BT 179 CTRP2 -16.7394 22.1101 -24.8652 68.917
BT 145 CTRP2 -15.422 -1.4439 -15.9125 86.6797
BT 231 CTRP2 -14.431 1.2092 -15.2987 82.6867
BT164 CTRP2 -13.453 2.5965 -14.5305 80.2333
BT 504 CTRP2 -13.3019 7.5189 -15.7041 74.8889
BT 286 CTRP2 -12.7531 4.828 -14.3198 77.0045
BT 112 CTRP2 -12.6692 4.2461 -14.075 77.5643
BT 428 CTRP2 -10.628 5.2914 -12.1274 73.9509
BT 359 CTRP2 -10.1724 8.0908 -12.4838 70.5338
BT 159 CTRP2 -10.1072 21.0402 -17.5189 62.8882
BT 172 CTRP2 -6.2653 9.0702 -8.5919 62.2211
BT 245 CTRP2 -6.0851 13.4574 -10.1097 59.5125
BT 416 CTRP2 -5.1554 3.9278 -5.8031 62.7083
BT 131 CTRP2 -4.4035 99.9587 -50.4992 51.0203
BT 216 CTRP2 -1.9025 9.1817 -3.9635 47.6533
BT147 CTRP2 -1.2996 10.0143 -3.6661 45.1988
BT 187 CTRP2 -1.2731 19.8505 -8.1115 47.0628
BT 482 CTRP2 -1.1541 10.1748 -3.5809 44.606
BT 340 CTRP2 -1.0246 12.9837 -4.6719 44.9551
BT 271 CTRP2 -0.7049 59.9315 -27.3262 48.4197
BT 330 CTRP2 -0.2729 60.9725 -27.4657 48.0506
BT 232 CTRP2 -0.1595 9.7454 -2.3634 39.6682
BT 440 CTRP2 0.425 30.5133 -11.7186 44.8773
BT 239 CTRP2 0.5321 22.2658 -7.5654 42.8266
BT 248 CTRP2 0.6028 2.9836 0.5675 29.7088
BT 333 CTRP2 0.7206 26.1769 -9.311 43.4031
BT 228 CTRP2 1.2903 21.1515 -6.3179 40.301
BT 422 CTRP2 1.4572 2.0825 1.4572 23.8982
BT 498 CTRP2 1.5211 20.6933 -5.8805 39.4001
BT 444 CTRP2 1.5997 18.3013 -4.6357 37.8623
BT 320 CTRP2 2.5645 3.4831 2.5623 16.5288
BT 224 CTRP2 4.0239 55.7841 -21.1808 43.2175
BT 328 CTRP2 5.0617 23.3571 -4.0975 29.9444
BT 139 CTRP2 7.3131 34.7541 -7.9647 31.8453
⏷ Show the Full List of 72 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 -7.5261 -5.8556 -7.5261 83.5456
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Becker CTRP2 -17.1725 -1.4558 -17.7861 87.2554
DK-MG CTRP2 -16.9624 1.1478 -18.0316 84.1172
Hs 683 CTRP2 -14.4308 -2.3844 -14.7364 87.6397
YH-13 CTRP2 -12.3055 -4.6767 -12.3521 90.6275
AM-38 CTRP2 -12.0438 -0.3025 -12.4635 83.0024
D283 Med CTRP2 -10.9827 2.3647 -11.7944 77.988
SF539 CTRP2 -10.8705 4.1105 -12.0782 75.6293
YKG-1 CTRP2 -6.3824 33.8105 -19.6989 55.2665
Daoy CTRP2 -6.3617 3.5695 -7.0339 67.1123
A-172 CTRP2 -5.5488 4.9755 -6.4975 63.2062
SF268 CTRP2 -5.2523 35.1093 -19.2433 53.7404
U-118MG CTRP2 -4.8355 13.5262 -8.8317 56.6259
M059K CTRP2 -2.669 56.0346 -27.1333 50.1937
LN-18 CTRP2 -1.7789 4.104 -2.1679 45.9815
LN-229 CTRP2 -1.3204 8.5272 -3.0877 44.8161
SNU-738 CTRP2 -1.0801 13.368 -4.9012 45.2679
CAS-1 CTRP2 -0.5399 3.5992 -0.7248 37.7505
GaMG CTRP2 -0.0104 29.908 -11.8159 45.6227
GMS-10 CTRP2 0.3466 43.1989 -18.0766 46.4511
KALS-1 CTRP2 0.6528 57.6367 -24.9955 47.023
KNS-42 CTRP2 0.9145 31.6204 -11.8249 44.1296
SNU-1105 CTRP2 1.196 40.8857 -16.1764 45.6956
SF295 CTRP2 1.2226 16.6822 -4.2017 38.2316
GOS-3 CTRP2 1.3722 94.3183 -42.6884 47.7422
GB-1 CTRP2 1.6951 14.5476 -2.7227 34.7678
SNU-626 CTRP2 1.8259 16.843 -3.713 36.0689
ONS-76 CTRP2 2.4338 17.5449 -3.4956 34.2851
SNU-466 CTRP2 2.5075 2.9783 2.5075 16.9014
KG-1-C CTRP2 3.1656 4.5635 3.1024 12.7327
SNU-201 CTRP2 3.437 4.0522 3.4353 10.7143
KNS-81 CTRP2 3.439 3.997 3.4381 10.6984
NMC-G1 CTRP2 3.4879 4.2452 3.4804 10.3946
DBTRG-05MG CTRP2 3.53 18.1778 -2.8235 30.6061
U-87MG ATCC CTRP2 3.6994 12.0803 0.351 21.7904
SW1783 CTRP2 4.1572 6.3913 3.5395 8.2759
42-MG-BA CTRP2 4.546 14.749 -0.2292 21.8178
SW1088 CTRP2 4.6601 47.4949 -16.5019 41.075
SF126 CTRP2 4.9546 26.0799 -5.5483 32.3904
T98G CTRP2 5.2503 22.0657 -3.2953 28.1158
TM-31 CTRP2 5.7932 67.7766 -25.6999 42.7787
SNB-75 CTRP2 6.1712 25.7142 -4.3671 28.4927
SNU-489 CTRP2 6.2027 23.9871 -3.4798 26.7965
CCF-STTG1 CTRP2 6.2971 49.4506 -16.1236 39.1586
U-251MG CTRP2 6.7837 31.9565 -6.9911 31.4204
8-MG-BA CTRP2 9.8213 30.2493 -3.8328 22.0762
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 CTRP2 -14.522 19.5708 -21.4887 68.2048
JHUEM-1 CTRP2 -14.0638 10.135 -17.3918 73.4502
JHUEM-7 CTRP2 -13.9967 0.3242 -14.6635 83.5634
HEC-151 CTRP2 -13.9174 21.6395 -21.7209 66.7304
MFE-296 CTRP2 -10.3016 18.2744 -16.5322 64.2709
RL95-2 CTRP2 -8.1625 -6.5728 -8.1625 87.6035
AN3-CA CTRP2 -7.9062 18.7943 -14.2752 60.6974
JHUEM-2 CTRP2 -7.7053 -5.3516 -7.7053 84.1236
HEC-1-A CTRP2 -6.5995 26.9753 -16.6741 56.6005
MFE-319 CTRP2 -6.1676 17.2253 -11.8026 58.287
HEC-265 CTRP2 -5.1569 5.2349 -6.1412 61.6825
KLE CTRP2 -5.0339 11.4473 -8.1836 57.8653
HEC-251 CTRP2 -4.5341 8.7325 -6.6057 57.5755
JHUEM-3 CTRP2 -4.5295 6.1667 -5.7306 58.8457
HEC-50B CTRP2 -3.3207 58.5557 -28.9666 50.759
HEC-108 CTRP2 -0.6166 842.8378 -418.5791 49.8799
HEC-6 CTRP2 0.6532 11.4027 -2.2633 36.8749
HEC-1-B CTRP2 2.2034 27.8533 -8.8063 43.4253
EN CTRP2 3.3168 24.5219 -6.169 36.102
HEC-59 CTRP2 4.8355 18.186 -1.7013 25.3645
EFE-184 CTRP2 5.2194 16.4098 -0.4931 21.2622
Ishikawa (Heraklio) 02 ER- CTRP2 -7.3094 -6.8961 -7.3094 82.3031
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Caki-2 CTRP2 -6.6212 17.2893 -12.2969 59.098
VMRC-RCW CTRP2 -2.4899 11.0956 -5.3622 50.1053
TUHR4TKB CTRP2 -2.4382 10.7055 -5.1461 49.9168
KMRC-3 CTRP2 -2.4169 5.3783 -3.1919 49.7709
BFTC-909 CTRP2 -0.4715 8.2735 -2.0858 40.3317
769-P CTRP2 0.0961 10.7411 -2.5319 39.0823
786-O CTRP2 0.2286 9.7285 -1.9538 37.6569
UO-31 CTRP2 0.6231 8.0295 -0.8296 33.8613
TUHR14TKB CTRP2 1.1716 10.0525 -1.1299 32.8846
SNU-1272 CTRP2 1.4954 16.0586 -3.6419 36.7809
TUHR10TKB CTRP2 2.1706 29.4406 -9.6242 41.0401
RCC10RGB CTRP2 3.3383 4.479 3.3009 11.4932
CAL-54 CTRP2 3.6406 35.7416 -11.4892 39.9202
VMRC-RCZ CTRP2 3.9156 16.6535 -1.7257 27.3419
KMRC-20 CTRP2 4.0478 14.8884 -0.7309 24.4047
OS-RC-2 CTRP2 4.3113 5.3572 4.1415 5.4998
KMRC-2 CTRP2 8.3916 35.2959 -7.3904 29.7117
Caki-1 CTRP2 9.047 28.7056 -3.6389 22.7374
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CL-34 CTRP2 -14.3901 1.7576 -15.3665 81.9756
GP2d CTRP2 -12.2144 3.9169 -13.4951 77.4682
SW948 CTRP2 -11.2553 -1.0836 -11.5213 83.5184
KM12 CTRP2 -11.1073 8.6292 -13.6771 71.3725
SK-CO-1 CTRP2 -10.2574 4.4604 -11.4991 74.3565
SNU-407 CTRP2 -9.9971 2.5783 -10.7692 76.3334
SW48 CTRP2 -9.5425 -7.6461 -9.5425 94.4333
SNU-61 CTRP2 -9.328 5.25 -10.6973 71.9823
SNU-175 CTRP2 -9.2151 0.2504 -9.5188 78.5265
LoVo CTRP2 -9.1596 7.0506 -11.0478 69.8636
CCK-81 CTRP2 -8.8567 -0.5012 -9.0483 79.123
SNU-81 CTRP2 -8.7648 1.3868 -9.2081 75.9168
NCI-H508 CTRP2 -8.6886 19.3965 -15.3428 61.6319
HT115 CTRP2 -8.0191 -6.3949 -8.0191 86.6892
T84 CTRP2 -7.6132 -2.2714 -7.6397 79.199
HCC-56 CTRP2 -7.5832 4.8929 -8.6953 68.9021
COLO205 CTRP2 -7.4947 -6.8117 -7.4947 83.5368
LS513 CTRP2 -7.4832 -5.8502 -7.4832 83.2884
HCT 15 CTRP2 -7.2039 0.7501 -7.4416 73.1741
SNU-C2A CTRP2 -7.0078 11.9954 -10.4937 62.1441
SNU-C5 CTRP2 -6.3737 19.6949 -13.1074 57.9159
SNU-503 CTRP2 -5.3219 260.8699 -131.6065 50.5902
COLO201 CTRP2 -5.1993 242.4713 -122.3099 50.6071
LS180 CTRP2 -5.1605 6.5021 -6.5222 60.803
SNU-C1 CTRP2 -4.1087 6.0713 -5.2429 57.3087
CW-2 CTRP2 -3.8835 9.9877 -6.3851 55.0376
LS1034 CTRP2 -3.6538 2.5871 -3.9078 56.867
NCI-H716 CTRP2 -3.6104 6.5518 -4.8516 55.1198
SW1417 CTRP2 -3.1833 11.6584 -6.3225 52.4278
MDST8 CTRP2 -2.7432 46.0638 -22.2689 50.3149
COLO 678 CTRP2 -2.6238 11.7152 -5.7625 50.5639
HT-55 CTRP2 -2.6141 6.499 -3.7517 50.7345
CL-11 CTRP2 -2.4649 9.7797 -4.7974 50.0164
COLO 320 CTRP2 -1.9799 5.033 -2.6183 47.3553
NCI-H747 CTRP2 -1.1373 7.6568 -2.56 43.5548
RKO CTRP2 -0.8713 31.5941 -13.4338 47.3696
LS123 CTRP2 -0.4605 12.4423 -3.8573 42.5304
DLD-1 CTRP2 -0.288 8.9738 -2.1745 39.8131
SW620 CTRP2 0.1789 17.543 -5.6109 42.283
SW1116 CTRP2 0.2302 10.6949 -2.3744 38.3938
C2BBe1 CTRP2 0.4349 5.5115 -0.121 32.5021
SNU-1033 CTRP2 0.4589 5.4788 -0.085 32.3106
OUMS-23 CTRP2 0.7923 2.8309 0.7735 28.3912
SNU-C4 CTRP2 1.7617 25.8886 -8.2257 40.8447
HT-29 CTRP2 2.4227 3.9449 2.3919 17.5697
RCM-1 [Human ESC] CTRP2 2.5928 10.2949 0.1739 25.1132
LS411N CTRP2 2.8613 4.5676 2.7731 14.8461
HCT 116 CTRP2 3.1058 4.2738 3.0787 13.0066
HCT 8 CTRP2 3.3195 4.5212 3.2747 11.6436
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PLC/PRF/5 CTRP2 -10.9228 36.5835 -25.4246 59.5692
SNU-182 CTRP2 -10.1089 5.953 -11.7496 72.4889
JHH-4 CTRP2 -9.6572 9.5851 -12.4347 68.5047
SNU-398 CTRP2 -9.3108 10.9676 -12.5613 66.9372
JHH-5 CTRP2 -7.275 19.3052 -13.8522 59.5277
SNU-886 CTRP2 -6.865 4.2428 -7.7428 67.8174
HuH-1 CTRP2 -5.8404 9.2317 -8.1932 61.0518
SNU-878 CTRP2 -5.4404 -0.0491 -5.5079 67.6778
SNU-423 CTRP2 -4.9665 51.8705 -27.1581 52.4031
JHH-2 CTRP2 -2.9008 32.2505 -15.6388 50.6754
Li-7 CTRP2 -2.11 7.6108 -3.5889 48.388
Hep-G2 CTRP2 0.1542 3.9615 -0.0405 33.2123
SNU-449 CTRP2 0.7595 6.2745 -0.0174 31.1024
HuH-6 CTRP2 1.1708 2.2483 1.1704 25.8078
SNU-387 CTRP2 1.4531 37.5906 -14.3106 44.1781
SK-HEP-1 CTRP2 1.8203 44.3891 -17.3754 44.5652
Hep 3B2.1-7 CTRP2 1.8333 4.7704 1.6108 22.1634
SNU-761 CTRP2 2.1482 16.2496 -3.6767 32.6335
JHH-6 CTRP2 6.553 14.0172 1.7448 11.041
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 147 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RERF-LC-A1 CTRP2 -16.4788 -0.3933 -17.2147 85.7273
NCI-H1339 CTRP2 -15.9326 9.2733 -19.1286 75.7308
NCI-H841 CTRP2 -15.8424 -0.396 -16.5283 85.4756
NCI-H520 CTRP2 -15.3908 2.0157 -16.5092 82.3098
DMS 273 CTRP2 -15.1369 3.0335 -16.4653 80.9896
NCI-H211 CTRP2 -15.0798 -0.6784 -15.6615 85.5069
PC-14 CTRP2 -15.0666 -2.2722 -15.4237 87.7017
NCI-H522 CTRP2 -15.03 -0.4428 -15.646 85.1696
NCI-H661 CTRP2 -14.5124 7.6759 -17.0711 75.8839
NCI-H2110 CTRP2 -14.4929 -1.9991 -14.8477 87.0973
LUDLU-1 CTRP2 -14.2313 0.8366 -15.0104 83.0351
NCI-H322 CTRP2 -14.1073 28.3669 -24.8434 64.4568
NCI-H446 CTRP2 -14.026 -3.5019 -14.2015 89.2123
DV-90 CTRP2 -13.9045 0.8332 -14.6563 82.8217
DMS 114 CTRP2 -13.6959 3.9915 -15.1298 78.8143
COR-L279 CTRP2 -13.5103 2.4049 -14.5501 80.5158
NCI-H1944 CTRP2 -13.494 6.4601 -15.5907 76.068
NCI-H2081 CTRP2 -12.9101 -1.5181 -13.2252 85.5572
NCI-H1341 CTRP2 -12.8878 1.9359 -13.7728 80.5778
EBC-1 CTRP2 -12.7688 12.5954 -16.877 70.3601
LC-1F CTRP2 -12.6969 -5.5363 -13.0084 85.5888
NCI-H1703 CTRP2 -12.6411 -4.3557 -12.7098 90.1797
NCI-H524 CTRP2 -12.6408 4.3278 -14.0651 77.4433
RERF-LC-MS CTRP2 -12.4357 9.1744 -15.3009 72.5316
COR-L51 CTRP2 -12.3757 -0.2749 -12.8229 83.2443
LCLC-97TM1 CTRP2 -12.3591 3.0992 -13.4549 78.6015
NCI-H2126 CTRP2 -12.2408 5.5877 -13.9706 75.6477
NCI-H23 CTRP2 -12.1567 -6.3839 -12.1642 93.7113
HARA [Human squamous cell lung carcinoma] CTRP2 -11.8626 1.9263 -12.6584 79.5981
VMRC-LCD CTRP2 -11.8476 16.3314 -17.3502 67.0962
NCI-H810 CTRP2 -11.8013 5.0174 -13.3324 75.7561
HCC44 CTRP2 -11.7747 -0.7086 -12.1197 83.3991
NCI-H1975 CTRP2 -11.7527 -2.3681 -11.9169 86.1629
NCI-H69 CTRP2 -11.6086 9.6149 -14.555 71.1956
NCI-H1694 CTRP2 -11.491 4.5682 -12.8734 75.887
NCI-H2171 CTRP2 -11.19 0.6168 -11.6899 80.736
NCI-H1184 CTRP2 -10.7688 9.8475 -13.7278 69.9198
LK2 CTRP2 -10.7244 -9.8502 -10.7244 99.6328
Lu-65 CTRP2 -10.0972 2.2885 -10.8174 76.8802
Calu-6 CTRP2 -10.0145 7.479 -12.1138 70.849
NCI-H1568 CTRP2 -9.831 7.0026 -11.7637 71.0132
NCI-H889 CTRP2 -9.7713 9.3866 -12.4884 68.8383
HCC4006 CTRP2 -9.6852 50.634 -30.9474 56.5017
SCLC-21H CTRP2 -9.6004 3.6116 -10.5707 74.3593
NCI-H2141 CTRP2 -9.4144 6.8336 -11.2575 70.5022
NCI-H2009 CTRP2 -8.6797 0.2418 -8.9472 77.5338
HCC1195 CTRP2 -8.647 33.2369 -21.6222 57.9432
COR-L88 CTRP2 -8.3835 12.9139 -12.3167 64.1761
COR-L47 CTRP2 -8.3121 19.4007 -14.9573 61.086
HCC1438 CTRP2 -8.2431 -1.1251 -8.3486 78.9021
NCI-H526 CTRP2 -8.2193 -7.2941 -8.2193 88.3206
MOR/CPR CTRP2 -8.1206 -7.0951 -8.1206 87.648
LOU-NH91 CTRP2 -8.0176 16.4019 -13.3617 61.8259
NCI-H2286 CTRP2 -7.8714 17.494 -13.6758 61.138
NCI-H1105 CTRP2 -7.7871 25.3618 -17.104 58.5652
EPLC-272H CTRP2 -7.6732 16.2015 -12.9184 61.3447
COLO 668 CTRP2 -7.5403 2.9944 -8.1892 71.0034
SBC-5 CTRP2 -7.3648 -6.9911 -7.3648 82.6721
NCI-H358 CTRP2 -7.3096 3.6229 -8.078 69.6667
HCC366 CTRP2 -7.3096 8.1689 -9.4042 65.2862
SHP-77 CTRP2 -7.0898 -6.1103 -7.0898 80.835
NCI-H1155 CTRP2 -6.9266 -4.2919 -6.9267 79.1433
HCC1588 CTRP2 -6.8117 -3.173 -6.8142 77.4641
LXF 289 CTRP2 -6.7222 12.5173 -10.3984 61.287
NCI-H1623 CTRP2 -6.4071 8.3028 -8.4732 63.0846
ChaGo-K-1 CTRP2 -6.3827 12.1852 -9.9062 60.7367
NCI-H1693 CTRP2 -6.375 10.4861 -9.2348 61.6244
NCI-H2029 CTRP2 -5.9802 12.7385 -9.7044 59.5952
NCI-H196 CTRP2 -5.9785 17.5485 -11.7506 57.8303
COLO 699 CTRP2 -5.8895 2.9437 -6.3871 66.2621
NCI-H1734 CTRP2 -5.5463 -0.1269 -5.6128 68.2469
NCI-H1581 CTRP2 -5.5149 1.7044 -5.7691 66.1857
DMS 53 CTRP2 -5.5132 6.1719 -6.804 62.152
NCI-H2170 CTRP2 -5.1266 17.3279 -10.7826 56.2126
HCC2279 CTRP2 -5.0596 2.2899 -5.3708 63.7499
NCI-H2106 CTRP2 -4.8958 23.5616 -13.4007 54.5608
NCI-H209 CTRP2 -4.6707 27.859 -15.2087 53.6477
HCC15 CTRP2 -4.6657 16.248 -9.8336 55.488
NCI-H1355 CTRP2 -4.2647 36.2256 -18.8513 52.4122
HCC95 CTRP2 -4.1249 4.5581 -4.8339 58.1454
HCC2108 CTRP2 -4.1184 16.0859 -9.203 54.2625
CAL-12T CTRP2 -4.0887 7.0214 -5.5251 56.8023
NCI-H1573 CTRP2 -3.958 41.7068 -21.2404 51.781
NCI-H1666 CTRP2 -3.5979 36.3662 -18.2955 51.5408
NCI-H1435 CTRP2 -3.3901 19.261 -9.9114 52.1581
COR-L95 CTRP2 -2.6055 37.1455 -17.7554 50.1973
NCI-H2087 CTRP2 -2.5888 11.0731 -5.4565 50.4606
Lu-99 CTRP2 -2.4341 33.1996 -15.6655 49.9598
NCI-H1651 CTRP2 -1.8681 9.1438 -3.9119 47.497
HCC827 CTRP2 -1.763 9.311 -3.8671 47.0658
NCI-H2122 CTRP2 -1.6893 73.1798 -34.7857 49.4364
SK-MES-1 CTRP2 -1.3356 31.7925 -13.9588 48.1729
Calu-3 CTRP2 -1.3172 9.3903 -3.428 45.0844
NCI-H647 CTRP2 -0.7731 27.8814 -11.5228 46.8553
NCI-H1092 CTRP2 -0.7204 15.6594 -5.5948 44.6305
NCI-H292 CTRP2 -0.637 24.3312 -9.6642 46.1351
NCI-H2405 CTRP2 -0.3501 10.7335 -2.9863 41.1978
NCI-H1793 CTRP2 -0.1496 25.9015 -9.976 45.2967
DMS 79 CTRP2 -0.1147 11.1683 -2.9362 40.3572
NCI-H2030 CTRP2 0.0295 12.8146 -3.5336 40.6697
Sq-1 CTRP2 0.2478 21.0849 -7.2555 43.25
NCI-H727 CTRP2 0.2544 9.708 -1.9183 37.5048
RERF-LC-Ad2 CTRP2 0.2655 17.2388 -5.3821 41.8785
HCC1833 CTRP2 0.4487 12.818 -3.1172 38.869
NCI-H2196 CTRP2 0.5109 12.925 -3.1051 38.6684
DMS 454 CTRP2 0.6763 11.3349 -2.2093 36.7057
NCI-H1915 CTRP2 0.7495 41.4732 -16.8623 45.7383
NCI-H1385 CTRP2 0.8977 3.9007 0.7721 28.0504
NCI-H2228 CTRP2 0.9373 28.0596 -10.0427 43.3607
NCI-H1869 CTRP2 1.2786 19.9075 -5.7192 39.7788
NCI-H1792 CTRP2 1.2836 39.8157 -15.5669 44.7612
NCI-H1650 CTRP2 1.301 15.1476 -3.3872 36.9004
HCC2935 CTRP2 1.5024 3.2014 1.4868 23.6495
A-549 CTRP2 1.5569 24.9145 -7.9282 41.02
T3M-10 CTRP2 1.6007 25.6925 -8.2734 41.175
NCI-H1838 CTRP2 1.7209 10.8537 -0.9448 30.8051
HOP-92 CTRP2 1.9234 18.0863 -4.2306 36.5802
NCI-H1563 CTRP2 2.0601 4.785 1.8545 20.5947
NCI-H2291 CTRP2 2.2305 4.9823 1.9902 19.5849
NCI-H441 CTRP2 2.6281 22.8475 -5.9432 37.1713
SK-LU-1 CTRP2 2.6453 28.2773 -8.6273 39.5701
EKVX CTRP2 2.9514 16.408 -2.4637 31.1731
NCI-H1755 CTRP2 3.0103 21.8493 -5.108 35.404
LCLC-103H CTRP2 3.0455 4.6843 2.9497 13.6463
NCI-H1395 CTRP2 3.1119 16.9658 -2.5946 31.0727
BEN CTRP2 3.4761 3.9285 3.4759 10.4488
NCI-H2085 CTRP2 3.4907 22.8934 -5.2058 34.5852
RERF-LC-Ad1 CTRP2 3.5722 17.0349 -2.218 29.2413
LC-1/sq-SF CTRP2 3.8235 28.2492 -7.5906 36.6969
NCI-H1299 CTRP2 3.865 18.498 -2.6889 29.6171
NCI-H2023 CTRP2 3.9393 25.342 -6.0394 34.8123
NCI-H1373 CTRP2 3.9668 30.2522 -8.4684 37.269
NCI-H2172 CTRP2 3.9764 18.8556 -2.7703 29.5512
HCC78 CTRP2 4.2279 25.8825 -6.0626 34.3282
NCI-H226 CTRP2 4.2309 5.3662 4.0518 6.0674
IA-LM CTRP2 4.3528 15.8011 -0.9206 24.2858
NCI-H650 CTRP2 4.3778 28.0506 -7.0188 35.1838
SW1271 CTRP2 4.7464 19.9762 -2.6713 27.7894
HOP-62 CTRP2 5.4151 22.5952 -3.424 28.0676
KNS-62 CTRP2 5.8783 21.1222 -2.3106 24.8581
NCI-H838 CTRP2 6.3622 22.7249 -2.7231 24.9428
NCI-H2444 CTRP2 6.5973 7.5886 4.7245 0.0947
COR-L105 CTRP2 7.3854 38.9615 -10.0049 33.8381
HCC1171 CTRP2 7.5194 22.2175 -1.5769 20.2541
NCI-H460 CTRP2 8.41 32.3659 -5.9229 27.6463
Calu-1 CTRP2 10.0583 31.3019 -4.1766 22.4402
Hs 888.Lu CTRP2 8.3568 33.0959 -6.3255 28.3143
⏷ Show the Full List of 147 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 -10.9701 -8.5046 -10.9701 97.439
SYO-1 CTRP2 -9.1712 12.9189 -13.1557 65.4539
P-STS CTRP2 -1.1241 17.4798 -6.8445 46.2994
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -4.2038 10.8458 -7.0643 55.7705
TOV-112D CTRP2 -16.2688 0.5708 -17.1644 84.4746
OC 314 CTRP2 -15.9846 -4.5049 -16.168 91.0583
A2780 CTRP2 -15.6139 1.5746 -16.6569 82.9547
COV434 CTRP2 -11.3439 7.4759 -13.5592 72.7084
OVK18 CTRP2 -10.6703 11.1885 -14.1033 68.7825
Caov-3 CTRP2 -9.5233 17.1795 -15.2593 63.7332
MCAS CTRP2 -9.3309 0.8712 -9.733 77.7397
SNU-8 CTRP2 -6.749 4.6633 -7.7241 67.0667
COV644 CTRP2 -5.391 3.2017 -5.899 64.2255
ONCO-DG-1 CTRP2 -3.7988 9.4663 -6.0928 54.9089
JHOM-1 CTRP2 -3.204 19.5606 -9.8657 51.7185
OVCAR-4 CTRP2 -2.3912 20.3707 -9.445 49.8392
COV362 CTRP2 -1.5101 17.0562 -7.0256 47.3612
OVCAR-5 CTRP2 -1.242 22.2642 -9.2368 47.2661
SNU-119 CTRP2 -0.8909 13.876 -4.9412 44.7182
OV7 CTRP2 -0.8195 23.7638 -9.5602 46.47
Kuramochi CTRP2 0.1018 15.5282 -4.7267 41.7251
SK-OV-3 CTRP2 0.1401 94.6486 -43.9075 48.4926
DOV13 CTRP2 0.2441 17.4082 -5.4838 42.0174
OAW42 CTRP2 0.3224 14.5812 -4.0648 40.4395
FU-OV-1 CTRP2 0.7267 24.6489 -8.5537 43.0022
OAW28 CTRP2 1.4217 31.2902 -11.2077 43.0796
RMG-I CTRP2 2.6573 27.4805 -8.2202 39.2382
OVSAHO CTRP2 3.2775 13.9483 -0.9539 26.794
OVISE CTRP2 3.77 19.0633 -3.0535 30.5465
ES2 CTRP2 4.6683 18.8236 -2.1611 26.8074
JHOS-2 CTRP2 4.7344 14.4993 0.0562 20.5089
IGROV-1 CTRP2 5.3746 23.625 -3.9721 29.1626
JHOC-5 CTRP2 6.8685 22.6498 -2.2882 23.0911
OVTOKO CTRP2 7.2668 25.1627 -3.228 24.5363
OVCAR-8 CTRP2 7.8346 42.6513 -11.4874 34.5648
EFO-27 CTRP2 8.262 31.5901 -5.6516 27.4337
HEY A8 CTRP2 8.4755 24.5998 -2.0421 19.9735
OV56 CTRP2 8.6454 17.8897 1.3177 9.5911
TYK-nu CTRP2 8.6875 25.2669 -2.2148 20.086
EFO-21 CTRP2 9.1803 32.835 -5.5727 26.0592
SNU-840 CTRP2 10.0472 33.9651 -5.4881 24.7964
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 0.0093 48.5176 -21.0187 47.2324
Yamato-SS CTRP2 0.0293 29.775 -11.7142 45.5277
HT-1080 CTRP2 -16.5737 -1.6674 -17.1123 87.3524
KYM-1 CTRP2 -16.2769 4.5372 -18.0877 80.1592
TE 617.T CTRP2 -15.3223 0.4526 -16.1182 84.1601
G-401 CTRP2 -15.1725 0.1485 -15.9009 84.4688
SW982 CTRP2 -14.7418 3.1238 -16.0563 80.6138
RD CTRP2 -12.5912 4.9779 -14.1837 76.6748
TE 441.T CTRP2 -10.6747 5.5524 -12.2516 73.7337
TTC-709 CTRP2 -9.5813 10.7522 -12.7726 67.5138
G-402 CTRP2 -9.5437 40.8233 -26.0923 57.5977
SK-UT-1 CTRP2 -7.7665 12.5987 -11.5373 63.2691
Rh41 CTRP2 -7.3219 -4.7943 -7.322 81.6528
GCT CTRP2 -5.6891 3.7381 -6.3402 64.7803
BT-12 CTRP2 -2.9885 13.14 -6.7508 51.6554
SK-LMS-1 CTRP2 -0.79 56.1065 -25.4981 48.3988
A-204 CTRP2 -0.5747 37.9469 -16.296 47.3534
BT-16 CTRP2 -0.1582 18.3878 -6.339 43.6293
MES-SA CTRP2 -0.0571 127.8493 -60.6595 48.9693
Hs 729.T CTRP2 1.5038 32.6916 -11.8304 43.2168
Rh18 CTRP2 2.4583 4.4488 2.3596 17.5667
Tm87-16 CTRP2 3.3035 24.8697 -6.354 36.3337
RKN CTRP2 7.1884 29.8191 -5.6046 28.9072
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 4.2826 14.8463 -0.505 23.227
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 CTRP2 -8.6943 -7.084 -8.6943 90.7358
MPP 89 CTRP2 -6.8352 8.2391 -8.9145 64.1602
JL-1 CTRP2 -6.3523 101.5892 -53.0261 51.9755
MSTO-211H CTRP2 -5.4462 12.2944 -8.961 58.5524
NCI-H2452 CTRP2 0.2687 49.2275 -21.1431 46.9699
IST-Mes1 CTRP2 4.0749 15.3822 -0.9531 24.9758
ACC-MESO-1 CTRP2 4.5545 5.0742 4.5014 3.4506
NCI-H2052 CTRP2 5.6322 19.6758 -1.7874 24.0449
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC CTRP2 -14.2702 10.6737 -17.8015 73.2374
22Rv1 CTRP2 -11.2793 6.4479 -13.1723 73.6157
DU145 CTRP2 -3.8694 24.6123 -12.89 52.6411
VCaP CTRP2 -0.4089 134.8609 -64.4625 49.1679
PaCa-3 CTRP2 0.8669 44.8482 -18.4377 45.9011
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 -7.5264 -7.0591 -7.5264 83.7486
A-253 CTRP2 0.8493 16.1965 -4.3228 39.3263
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-435S CTRP2 -16.1642 6.6574 -18.5611 78.0915
CJM [Human melanoma] CTRP2 -15.2243 -3.4964 -15.4586 89.5068
WT2-iPS CTRP2 -12.1014 25.7474 -21.6344 63.4412
Hs 944.T CTRP2 -11.3783 10.0096 -14.4433 70.5947
A2058 CTRP2 -11.0068 -8.6385 -11.0068 97.6836
G-361 CTRP2 -10.8249 2.9157 -11.7429 77.0553
WM88 CTRP2 -10.5091 17.7634 -16.5337 64.7677
Hs 852.T CTRP2 -10.181 16.3253 -15.5927 65.0378
IGR-1 CTRP2 -8.4197 4.5602 -9.52 71.07
K029AX CTRP2 -8.2276 29.1202 -19.2808 58.2712
COLO 829 CTRP2 -8.1464 29.8881 -19.5591 58.0166
MeWo CTRP2 -8.0289 22.4342 -16.0152 59.6816
Hs 936.T CTRP2 -6.7886 37.3397 -21.7807 55.3057
WM115 CTRP2 -5.9892 27.9472 -16.5319 55.5787
IGR-37 CTRP2 -4.7526 13.14 -8.5827 56.5418
SK-MEL-24 CTRP2 -4.6588 3.0907 -5.0826 61.3859
COLO 741 CTRP2 -4.3881 11.2908 -7.4379 56.1632
HMCB CTRP2 -4.3335 0.6645 -4.406 61.4971
WM983B CTRP2 -4.0381 61.758 -31.1967 51.3098
A-375 CTRP2 -3.6656 6.8808 -5.0192 55.2319
IGR-39 CTRP2 -3.3785 30.5701 -15.2737 51.4561
RPMI-7951 CTRP2 -3.2586 7.4604 -4.7752 53.4319
LOX-IMVI CTRP2 -2.4318 12.2466 -5.7899 49.9021
WM1799 CTRP2 -2.2894 10.9753 -5.1024 49.37
COLO 800 CTRP2 -1.0086 18.4241 -7.1777 46.1323
Mel Ho CTRP2 -0.6569 5.4773 -1.301 39.6007
Mel JuSo CTRP2 0.0268 34.1622 -13.8817 46.081
Hs 294T CTRP2 0.2844 81.47 -37.2041 48.1498
COLO 792 CTRP2 0.6372 20.8985 -6.8 42.0992
HT-144 CTRP2 0.8065 39.9733 -16.0664 45.4964
WM793 CTRP2 0.8149 16.8066 -4.649 39.7835
A101D CTRP2 0.8723 35.7764 -13.9234 44.8679
SK-MEL-3 CTRP2 1.1375 11.6529 -1.894 34.7108
Hs 940.T CTRP2 1.519 2.5791 1.5183 23.489
Malme-3M CTRP2 1.7278 3.8614 1.666 22.3045
SK-MEL-1 CTRP2 1.9198 3.6354 1.8917 20.9109
Hs 934.T CTRP2 2.4329 3.0649 2.4328 17.3983
Hs 688(A).T CTRP2 3.1149 4.7758 3.0055 13.2323
SK-MEL-30 CTRP2 3.3784 4.7464 3.2981 11.375
SK-MEL-28 CTRP2 3.6789 3.9324 3.6789 9.097
Hs 839.T CTRP2 4.4993 4.914 4.4794 3.6994
Hs 895.T CTRP2 4.5125 4.9791 4.4803 3.6547
UACC-257 CTRP2 4.8613 23.9586 -4.5657 31.0867
SK-MEL-31 CTRP2 7.0448 24.396 -3.019 24.4494
IPC-298 CTRP2 7.8025 28.9998 -4.7196 26.5589
WM266-4 CTRP2 8.4168 52.1777 -15.7741 36.8203
SK-MEL-5 CTRP2 9.4933 27.2337 -2.5966 19.8549
UACC-62 CTRP2 10.7438 40.2838 -8.0805 27.7048
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH-10-TC CTRP2 -14.3702 11.6961 -18.2709 72.5915
HuG1-N CTRP2 -12.9935 1.4028 -13.7795 81.3713
IM95 CTRP2 -12.6732 -3.6151 -12.7839 88.8977
NCC-StC-K140 CTRP2 -12.5226 -0.0578 -13.0136 83.0392
HGC-27 CTRP2 -12.3345 7.7036 -14.7094 73.6903
SNU-16 CTRP2 -11.6135 -9.9018 -11.6135 99.4089
NUGC-3 CTRP2 -10.4483 4.0703 -11.6076 75.0952
SNU-1 CTRP2 -9.6954 19.9113 -16.604 62.8024
NUGC-4 CTRP2 -8.7805 3.4275 -9.6344 73.1377
GSS CTRP2 -8.1666 -6.1965 -8.1666 87.2599
OCUM-1 CTRP2 -7.8186 12.9093 -11.7158 63.1913
23132/87 CTRP2 -7.7669 -6.2675 -7.7669 85.1733
SNU-5 CTRP2 -7.7234 -2.379 -7.7489 79.7195
SNU-620 CTRP2 -7.4657 -6.8714 -7.4657 83.3438
ECC12 CTRP2 -7.3044 4.3042 -8.2375 68.8776
SNU-601 CTRP2 -6.4616 15.3396 -11.2923 59.5141
SNU-216 CTRP2 -5.8827 21.3305 -13.3516 56.6648
ECC10 CTRP2 -5.796 5.317 -6.8616 63.7053
NCI-N87 CTRP2 -5.3924 2.1802 -5.7109 65.2143
MKN74 CTRP2 -4.8345 17.9343 -10.7567 55.4681
Fu97 CTRP2 -3.7822 8.4901 -5.7085 55.1452
KATO III CTRP2 -2.7704 38.9251 -18.7804 50.4028
SNU-719 CTRP2 -1.8025 8.1874 -3.4718 47.0299
AGS CTRP2 0.1615 20.0274 -6.824 43.1793
KE-39 CTRP2 0.3103 11.1658 -2.5027 38.3507
SNU-668 CTRP2 0.4624 7.4569 -0.773 34.2513
GSU CTRP2 0.4714 5.9293 -0.2132 32.657
MKN7 CTRP2 0.8758 5.5585 0.3449 29.5625
MKN1 CTRP2 1.5337 4.9396 1.2411 24.4031
Hs 746.T CTRP2 3.883 44.0968 -15.4579 41.5353
MKN45 CTRP2 4.621 5.05 4.5808 2.9615
LMSU CTRP2 8.4037 33.792 -6.6348 28.6891
SNG-M CTRP2 -13.0629 2.7384 -14.1381 79.7205
SNU-685 CTRP2 -0.4108 17.837 -6.3194 44.2415
SNU-1077 CTRP2 7.9759 21.489 -0.8812 17.6298
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FTC-238 CTRP2 -17.8086 0.1133 -18.7432 85.6094
SW579 CTRP2 -12.0688 11.0059 -15.5424 70.683
CAL-62 CTRP2 -8.5212 11.0704 -11.7528 65.5529
8305C CTRP2 -7.2674 13.8388 -11.5089 61.7001
TT2609-C02 CTRP2 -6.9402 81.3696 -43.5145 52.7754
ML-1 [Human leukemia] CTRP2 -5.0588 26.0877 -14.7463 54.4663
TT CTRP2 -4.7889 2.8826 -5.1835 62.1036
FTC-133 CTRP2 -0.349 173.2533 -83.5958 49.3324
8505C CTRP2 -0.0984 15.3795 -4.8523 42.383
B-CPAP CTRP2 3.4292 4.5318 3.3906 10.8919
CGTH-W-1 CTRP2 4.8544 16.517 -0.851 23.0459
BHT-101 CTRP2 5.6181 18.2318 -1.0775 22.1939
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PE/CA-PJ34 (clone C12) CTRP2 -17.4226 -1.187 -18.0974 86.9988
PE/CA-PJ49 CTRP2 -16.0318 -3.1399 -16.3464 89.1684
HSC-2 CTRP2 -15.4502 7.1357 -17.9263 77.1356
BICR 6 CTRP2 -14.2221 13.5576 -18.7948 71.2084
SCC-4 CTRP2 -14.0385 5.8629 -16.0105 77.1536
BICR 22 CTRP2 -13.6228 10.9739 -17.2074 72.3895
PE/CA-PJ15 CTRP2 -13.0329 12.3345 -17.0638 70.8196
SCC-25 CTRP2 -11.942 9.2842 -14.8029 71.869
CAL-27 CTRP2 -11.2374 -7.883 -11.2375 96.3285
CAL-33 CTRP2 -9.8016 15.2934 -14.7712 65.0503
BICR 16 CTRP2 -8.2337 22.6042 -16.299 59.9151
YD-10B CTRP2 -7.5668 -7.0005 -7.5668 84.0173
SNU-1214 CTRP2 -7.1431 3.1579 -7.7926 69.7922
SNU-1076 CTRP2 -6.7687 3.29 -7.4144 68.614
BICR 56 CTRP2 -4.0952 25.775 -13.6606 52.9284
Detroit 562 CTRP2 -2.1968 10.99 -5.0117 54.7805
BICR 18 CTRP2 -1.1493 127.0056 -61.1715 49.4387
SNU-46 CTRP2 0.0846 12.4944 -3.3319 40.2523
HSC-3 CTRP2 0.139 38.2879 -15.8236 48.4454
SNU-899 CTRP2 0.1403 7.3432 -1.0734 36.108
SCC-9 CTRP2 0.9399 54.1361 -23.0006 46.522
BICR 31 CTRP2 1.1233 38.5511 -15.0792 44.8415
FaDu CTRP2 1.9454 14.5054 -2.4648 33.635
BHY CTRP2 2.1127 20.5445 -5.2665 37.4673
SNU-1041 CTRP2 3.741 24.8644 -5.9718 35.0892
SNU-1066 CTRP2 5.1512 22.0258 -3.3575 28.4204
YD-8 CTRP2 6.194 20.1884 -1.5922 22.5252
PE/CA-PJ41 (clone D2) CTRP2 7.7735 22.3909 -1.4728 19.578
HSC-4 CTRP2 9.7737 25.5054 -1.5634 16.9289
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCaBER CTRP2 -13.1485 -0.2859 -13.6497 83.8508
BC-3C CTRP2 -12.4112 13.1749 -16.7114 69.5847
U-BLC1 CTRP2 -11.1146 8.6076 -13.6778 71.4006
647V CTRP2 -11.0609 2.7372 -11.9598 77.5914
SW1710 CTRP2 -11.0374 6.6058 -12.9561 73.1427
RT-112 CTRP2 -9.4726 -3.9927 -9.4874 86.8084
RT-4 CTRP2 -8.1477 7.9323 -10.2332 67.2143
JMSU-1 CTRP2 -8.0217 2.1897 -8.5493 73.1982
5637 CTRP2 -7.5739 -6.2887 -7.5739 84.0002
T24 CTRP2 -7.2677 53.1944 -29.9293 54.3295
UM-UC-1 CTRP2 -2.9979 64.3467 -31.5495 50.436
KMBC-2 CTRP2 -1.8795 40.3066 -18.6441 49.2528
CAL-29 CTRP2 -0.1509 10.2065 -2.5522 39.9291
VM-CUB-1 CTRP2 -0.0745 22.8802 -8.431 44.5443
BFTC-905 CTRP2 -0.0537 6.71 -1.049 36.7431
253J-BV CTRP2 0.2553 10.2677 -2.1606 37.9452
UM-UC-3 CTRP2 2.3303 74.062 -31.7515 46.3537
639V CTRP2 2.3738 2.8693 2.3738 17.792
HT-1197 CTRP2 3.0062 10.5474 0.4526 23.116
TCCSUP CTRP2 5.3785 28.4348 -6.3736 32.7838
J82 CTRP2 5.6886 21.1983 -2.5022 25.6402
KU-19-19 CTRP2 6.2964 18.6104 -0.7256 19.9455
HT-1376 CTRP2 7.4451 27.5289 -4.2652 26.2861
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 5.0328 19.4359 -2.161 26.0888

References

1 ClinicalTrials.gov (NCT00343564) A Study of SB-743921 in Non-Hodgkin's Lymphoma. U.S. National Institutes of Health.
2 Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2009 Jan-Feb;31(1):47-57.