Details of the Drug

General Information of Drug (ID: DM7TX3D)

Drug Name

CM-156

Synonyms

Sigma opioid antagonists (addiction); Sigma opioid antagonists (addiction), University of Mississippi; 2(3H)-benzoxalones and 2(3H)-benzothiazolones (addiction), University of Mississippi

Indication

Disease Entry	ICD 11	Status	REF
Drug abuse	6C4G.1Z	Investigative	[1]
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Structure

3D Structure is Not Available

3D MOL

2D MOL

Cross-matching ID

TTD ID: D0J9VK

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Opioid receptor sigma 1 (OPRS1)	TT5TPI6	SGMR1_HUMAN	Antagonist	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Drug abuse

ICD Disease Classification

6C4G.1Z

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Opioid receptor sigma 1 (OPRS1)	DTT	SIGMAR1	2.77E-06	-0.12	-0.62

Molecular Expression Atlas (MEA)

MEA Detail

Jump to Detail Molecular Expression Atlas of This Drug

References

1	Antitussives and substance abuse. Subst Abuse Rehabil. 2013 Nov 6;4:75-82.