Details of the Drug

General Information of Drug (ID: DM8G6O4)

Drug Name
AHPN
Synonyms Ro 47-2077; 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid; CD437; CD 437
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 398.5
Logarithm of the Partition Coefficient (xlogp) 7.4
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C27H26O3
IUPAC Name
6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid
Canonical SMILES
C1C2CC3CC1CC(C2)(C3)C4=C(C=CC(=C4)C5=CC6=C(C=C5)C=C(C=C6)C(=O)O)O
InChI
InChI=1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30)
InChIKey
LDGIHZJOIQSHPB-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
135411
ChEBI ID
CHEBI:88334
CAS Number
125316-60-1
TTD ID
D0A6NQ
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Retinoic acid receptor gamma (RARG) TT1Q3IE RARG_HUMAN Agonist [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
14-3-3 protein zeta/delta OT2TKG9P 1433Z_HUMAN Gene/Protein Processing [3]
26S proteasome complex subunit SEM1 (SEM1) OTASLBM1 SEM1_HUMAN Gene/Protein Processing [3]
26S proteasome non-ATPase regulatory subunit 3 (PSMD3) OT585WY8 PSMD3_HUMAN Gene/Protein Processing [3]
5'-3' exoribonuclease 2 OT7PNO08 XRN2_HUMAN Gene/Protein Processing [3]
Actin-related protein 2/3 complex subunit 2 (ARPC2) OTSOKOMY ARPC2_HUMAN Gene/Protein Processing [3]
Actin-related protein 2/3 complex subunit 3 (ARPC3) OTKWVF8P ARPC3_HUMAN Gene/Protein Processing [3]
Activated RNA polymerase II transcriptional coactivator p15 (SUB1) OTK71JYU TCP4_HUMAN Gene/Protein Processing [3]
Adenomatous polyposis coli protein 2 (APC2) OTRH91CX APCL_HUMAN Gene/Protein Processing [3]
Adenylate kinase 2, mitochondrial (AK2) OTZG3X2H KAD2_HUMAN Gene/Protein Processing [3]
ADP-ribosylation factor 1 (ARF1) OT5C4C3L ARF1_HUMAN Gene/Protein Processing [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Retinoic acid receptor gamma (RARG) DTT RARG 5.43E-04 -0.14 -0.37
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 138 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 0.6255 1.9604 0.622 25.3331
JM1 CTRP2 -1.5126 1.8082 -1.5476 44.7775
SK-MM-2 CTRP2 -4.8167 11.2662 -7.8252 57.8231
THP-1 CTRP1 -3.5057 -1.7214 -3.5057 98.6752
SUP-M2 CTRP2 -3.2889 -2.6399 -3.2889 56.5134
SU-DHL-5 CTRP1 -3.2035 -2.1009 -3.2035 99.5831
HEL CTRP2 -3.1936 -2.7141 -3.1936 52.6035
NALM-6 CTRP2 -3.1434 -2.3131 -3.1434 52.2445
MV4-11 CTRP2 -3.1422 -2.1722 -3.1422 52.236
CML-T1 CTRP2 -3.0993 -2.3885 -3.0993 51.9295
JVM-3 CTRP2 -3.0504 -1.8609 -3.0504 51.5804
SU-DHL-1 CTRP2 -3.0227 -2.5744 -3.0227 51.3828
KE-37 CTRP2 -2.9481 -1.71 -2.9481 54.2473
P12-Ichikawa CTRP2 -2.8455 -1.6576 -2.8455 53.5647
EoL-1 CTRP2 -2.8386 -1.9353 -2.8386 53.5188
JVM-2 CTRP2 -2.6944 0.9156 -2.744 49.0642
697 CTRP2 -2.4947 -0.863 -2.4947 51.232
MOLT-3 CTRP2 -2.4853 -0.7147 -2.4854 51.1692
M-07e CTRP2 -2.3989 -0.7153 -2.399 50.5949
OCI-AML-3 CTRP2; CTRP1 -2.3917 -1.5387 -2.3917 50.5469
AML-193 CTRP2 -2.353 -0.7122 -2.353 50.2895
JURL-MK1 CTRP2 -2.3262 -0.4229 -2.3265 50.1118
SEM CTRP2 -2.3138 -1.4427 -2.3138 50.0294
NU-DHL-1 CTRP2 -2.2612 0.8261 -2.2749 49.6821
HEL 92.1.7 CTRP2 -2.2477 -1.7149 -2.2477 41.822
NU-DUL-1 CTRP2; CTRP1 -2.2079 -1.3451 -2.2079 49.3247
TALL-1 [Human adult T-ALL] CTRP2 -2.0846 4.762 -2.6331 48.7507
MOLM-13 CTRP2 -1.8911 -0.1267 -1.8913 47.2185
P31/FUJ CTRP2 -1.7817 0.1053 -1.7834 42.5225
SET-2 CTRP2 -1.7212 0.6892 -1.7314 42.1166
KE-97 CTRP2; CTRP1 -1.5746 0.4149 -1.5756 45.1159
MOLM-6 CTRP2 -1.4499 3.9241 -1.8978 41.2605
Kasumi-2 CTRP2 -1.436 0.6856 -1.438 44.1975
OCI-AML-2 CTRP2 -1.4225 -0.4211 -1.4225 44.1018
L-540 CTRP2 -1.363 0.7685 -1.3652 43.7129
OCI-Ly3 CTRP2 -1.1604 5.0883 -1.7094 43.3955
Mono-Mac-1 CTRP2 -1.0273 2.5875 -1.1 41.6667
Ku812 CTRP2; CTRP1 -0.9627 1.7396 -0.9788 41.092
KCL-22 CTRP2 -0.8705 1.4186 -0.8869 36.0651
Karpas-299 CTRP2 -0.7898 0.4023 -0.7898 39.8946
NB4 CTRP2 -0.7878 0.146 -0.7878 39.8812
EB1 CTRP2 -0.7497 3.089 -0.8614 39.9415
Namalwa CTRP2 -0.7236 2.5761 -0.7803 39.6213
KM-H2 CTRP2 -0.7064 1.2628 -0.7141 34.8626
DND-41 CTRP2 -0.6285 1.6225 -0.6354 38.8442
SUP-T1 CTRP2 -0.6148 2.2295 -0.6433 38.8191
GDM-1 CTRP2; CTRP1 -0.5603 1.5795 -0.5655 38.3851
PL21 CTRP2; CTRP1 -0.496 1.6905 -0.5024 37.9617
SUP-HD1 CTRP2 -0.4954 2.9889 -0.58 38.1927
Mono-Mac-6 CTRP2 -0.4925 6.1589 -1.8969 33.3199
GA-10 CTRP2 -0.4716 2.0151 -0.4865 37.8263
NOMO-1 CTRP2; CTRP1 -0.4617 0.1374 -0.4617 37.713
A3/Kawakami CTRP2 -0.4385 0.7214 -0.4385 37.5583
DEL CTRP2 -0.3822 1.3115 -0.3833 37.1876
MOLM-16 CTRP1 -0.364 1.518 -0.3666 77.5197
SKM-1 CTRP2; CTRP1 -0.3404 0.1796 -0.3404 36.9062
BL-41 CTRP2 -0.3295 7.535 -1.5986 39.8064
EJM CTRP2; CTRP1 -0.3268 3.3675 -0.4473 37.1842
Ki-JK CTRP2 -0.3048 3.6399 -0.5796 32.9217
RPMI-8402 CTRP2 -0.3033 1.9358 -0.3282 32.0446
BV-173 CTRP2 -0.2947 0.4581 -0.2947 36.602
RPMI-6666 CTRP2 -0.2262 3.0046 -0.2974 36.3723
SR CTRP2 -0.1848 0.4949 -0.1848 35.8715
MOLT-13 CTRP2 -0.117 0.6778 -0.117 35.4205
Jurkat CTRP2 -0.1134 2.1479 -0.145 30.7124
OCI-Ly19 CTRP2 -0.1124 3.0925 -0.1864 35.6267
HD-MY-Z CTRP2 -0.1105 2.9225 -0.2295 31.0042
CA46 CTRP2 -0.107 2.9859 -0.17 35.5565
HuT 78 CTRP2 -0.0493 3.9876 -0.2481 35.5898
Reh CTRP2 -0.0428 0.8074 -0.0428 34.927
ALL-SIL CTRP2 -0.0365 2.489 -0.0602 34.9629
KMS-20 CTRP2 -0.0355 2.8409 -0.0823 35.0307
Granta-519 CTRP2 -0.0301 3.5244 -0.1522 35.2311
LAMA-84 CTRP2 0.0025 2.5802 -0.0629 30.0063
NCO2 CTRP2 0.0409 3.1878 -0.0347 34.6155
JeKo-1 CTRP2 0.0471 2.1328 0.0228 29.5398
KHM-1B CTRP2 0.1222 3.068 -0.0028 29.3674
PF-382 CTRP2 0.1528 2.4684 0.1072 28.8615
HT CTRP2; CTRP1 0.1557 1.8883 0.1531 33.6156
EHEB CTRP2 0.1728 4.4504 -0.272 30.1524
KMS-27 CTRP2 0.2017 2.4926 0.1564 28.5111
SUP-T11 CTRP2 0.2934 4.3132 0.0599 33.4445
KMS-11 CTRP1 0.3242 3.4533 0.2348 66.2838
L-428 CTRP2 0.364 2.1658 0.3595 32.237
SU-DHL-4 CTRP2; CTRP1 0.399 2.9991 0.359 32.122
BL-70 CTRP2; CTRP1 0.4007 2.4649 0.3895 32.015
A4/Fukuda CTRP2 0.4329 2.2935 0.3709 21.4912
OCI-AML-5 CTRP2 0.4466 1.0968 0.4466 31.6728
KO52 CTRP2 0.4848 2.2957 0.4661 26.3928
EM-2 CTRP2 0.4943 1.208 0.4943 31.3554
REC-1 CTRP2 0.5075 4.119 0.3293 31.856
SU-DHL-8 CTRP2 0.5226 1.6193 0.518 20.5784
Peer CTRP2 0.5276 1.9234 0.5235 26.0345
U-937 CTRP2; CTRP1 0.5409 1.385 0.5409 31.0458
Daudi CTRP2 0.5524 2.0373 0.551 30.9737
DB CTRP2 0.579 3.2552 0.4576 26.0954
MHH-CALL-4 CTRP2 0.5791 6.1324 -0.1229 33.0157
SUP-B15 CTRP2 0.586 1.3604 0.586 30.7458
WSU-DLCL2 CTRP2; CTRP1 0.5945 1.3758 0.5945 30.6889
Hs 611.T CTRP2 0.5992 4.0582 0.4393 31.1892
MM1.S CTRP2 0.6562 1.5639 0.656 25.1022
CMK CTRP2 0.6653 1.0829 0.6653 30.2184
RPMI-8226 CTRP2; CTRP1 0.6893 2.0712 0.6884 30.0617
MOTN-1 CTRP2 0.717 3.001 0.6446 24.9297
OCI-M1 CTRP2 0.7253 1.3569 0.7253 24.6078
SIG-M5 CTRP2 0.7282 1.0774 0.7282 24.5868
SU-DHL-6 CTRP2 0.7289 2.3717 0.7252 29.8076
U266B1 CTRP2 0.7537 2.1728 0.7524 29.635
KMS-21-BM CTRP2 0.7622 3.0253 0.7351 29.6644
RL CTRP2 0.7862 3.905 0.546 25.0613
HL-60 CTRP2 0.8237 1.4276 0.8237 23.9047
ST486 CTRP2 0.8315 2.9443 0.8114 29.1802
NCI-H929 CTRP2 0.9042 4.2113 0.5946 24.4836
TF-1 CTRP2 0.9055 2.4118 0.8939 23.3617
MC116 CTRP2; CTRP1 0.921 1.4122 0.921 28.5179
KMS-26 CTRP2 1.026 1.8545 1.0258 22.4604
K-562 CTRP2 1.0921 2.3231 1.0875 22.0039
Ci-1 CTRP2 1.103 1.934 1.1028 21.91
F-36P CTRP2 1.213 2.4978 1.2117 26.5806
Raji CTRP2 1.2399 4.2955 1.0883 26.9121
L-363 CTRP2 1.2554 2.8657 1.2488 26.3163
HDLM-2 CTRP2 1.3766 5.9962 0.4829 23.4114
OPM-2 CTRP2 1.4305 5.0438 1.1295 26.1647
Karpas-422 CTRP2 1.4325 2.6196 1.4315 25.1198
ME1 CTRP2 1.4661 4.4404 1.3056 25.4404
Kasumi-1 CTRP2 1.5211 2.5799 1.5206 24.5288
MHH-CALL-3 CTRP2 1.5914 7.4732 0.4746 27.9094
KYO-1 CTRP2 1.8073 3.1722 1.8021 22.6415
KMS-18 CTRP2 1.8835 7.2267 0.8823 25.6563
KMM-1 CTRP2 2.1265 7.7728 0.473 21.2635
P3HR-1 CTRP2; CTRP1 2.4086 3.9748 2.3811 18.7177
AMO1 CTRP2; CTRP1 2.9787 6.865 2.1846 17.7601
OCI-Ly10 CTRP2; CTRP1 3.6184 11.6064 0.6044 22.0308
Karpas-620 CTRP2 3.7242 5.9757 3.3299 11.3134
LP-1 CTRP2; CTRP1 3.9399 5.6525 3.6819 9.3712
JJN-3 CTRP2 4.0322 7.4395 3.0077 11.7866
MOLP-2 CTRP2 4.3612 13.8725 0.1522 21.8458
Toledo CTRP2 4.5552 19.7877 -2.6318 28.7277
⏷ Show the Full List of 138 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 -0.2129 4.9511 -0.6396 37.2821
TE8 CTRP2 2.8207 10.4599 0.4001 24.7065
TE-14 CTRP2 -0.528 5.8722 -1.2448 39.9041
KYSE-140 CTRP2; CTRP1 0.3766 3.4904 0.2859 32.4375
OE33 CTRP2 0.4515 5.1876 -0.2055 28.9582
KYSE-510 CTRP2 0.6644 2.8809 0.6423 30.298
TE-4 CTRP2 0.6918 2.8476 0.6724 30.1068
TE-9 CTRP2 0.7186 1.695 0.7182 24.6569
OE21 CTRP2 0.7655 3.5221 0.6093 24.8941
TE-11 CTRP2 0.7863 1.4097 0.7863 24.1721
TE-10 CTRP2 0.9743 4.3586 0.6292 24.1205
KYSE-180 CTRP2 1.07 2.5002 1.0589 22.185
EC-GI-10 CTRP2 1.1922 4.6394 0.7809 22.8272
KYSE-150 CTRP2 1.5267 4.5039 1.3586 25.0642
TE-5 CTRP2 1.5643 3.5011 1.477 18.9337
KYSE-450 CTRP2; CTRP1 1.6613 4.1389 1.5682 23.9107
KYSE-70 CTRP2 1.9676 4.1652 0.2994 3.4618
TE-6 CTRP2 2.1659 6.424 1.492 22.6473
TE-1 CTRP2 2.2067 4.9762 1.7635 15.7456
KYSE-30 CTRP2 2.7458 6.1804 2.2048 18.3337
COLO 680N CTRP2 3.2027 6.7361 2.473 16.0409
OE19 CTRP2 3.4765 6.3904 2.4396 9.3632
KYSE-520 CTRP2 3.5862 6.8652 2.3094 9.6762
KYSE-410 CTRP2; CTRP1 4.0376 6.6731 3.3644 10.341
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 4.434 6.8807 3.0278 4.6268
KP-4 CTRP2 0.5235 3.4192 0.4503 31.4048
PSN1 CTRP2 0.861 3.3201 0.816 29.0675
SU.86.86 CTRP2 0.9692 3.4806 0.9145 28.3808
Panc 03.27 CTRP2; CTRP1 1.0072 2.5029 1.0043 27.9543
BxPC-3 CTRP2 1.2242 2.3096 1.2216 21.053
MIA PaCa-2 CTRP2 1.324 2.7056 1.3105 20.3792
SW1990 CTRP2 1.3491 4.3584 1.038 21.3227
KP-3 CTRP2; CTRP1 1.4685 4.5786 1.2802 25.5208
L3.3 CTRP2 1.5091 2.1215 1.5091 19.0085
Panc 08.13 CTRP2 1.5148 5.5811 1.0701 26.1097
Panc 10.05 CTRP2; CTRP1 1.8069 4.0495 1.7365 22.8648
YAPC CTRP2 1.9098 10.9886 -2.4374 23.0934
PaTu 8988t CTRP2 2.0184 3.5598 1.9559 15.5983
Panc 05.04 CTRP2 2.1759 4.7329 0.1669 3.795
QGP-1 CTRP2; CTRP1 2.2535 6.5928 1.5229 22.2807
DAN-G CTRP2 2.3039 5.4402 1.9727 20.4849
TCC-Pan2 CTRP2 2.3265 4.0052 0.5891 1.4306
HuP-T4 CTRP2; CTRP1 2.5783 4.7688 2.4452 17.9545
Capan-2 CTRP2; CTRP1 2.6199 7.0425 1.7346 20.4577
Capan-1 CTRP2 2.7423 6.3626 1.7368 14.324
PK-59 CTRP2 2.8677 5.039 2.4439 10.9774
HuP-T3 CTRP2 2.9049 5.8472 2.1346 12.1781
Panc 02.03 CTRP2 3.1748 6.0014 2.3338 10.5952
Panc 04.03 CTRP2 3.2534 6.0626 2.3823 10.1787
HPAC CTRP2; CTRP1 3.2866 4.9537 3.1749 13.1717
PANC-1 CTRP2 3.5085 8.7984 1.2837 14.3785
CFPAC-1 CTRP2; CTRP1 3.531 8.6328 1.9558 17.2217
AsPC-1 CTRP2 4.0738 6.9011 2.7234 6.7213
Hs 766T CTRP2 4.3677 6.4873 3.7818 7.8371
PaTu 8988s CTRP2 4.5253 8.6676 2.2099 8.119
PK-45H CTRP2 5.2947 8.9684 2.631 4.9236
KP-2 CTRP2 5.3519 8.1463 3.0593 3.0232
HPAF-II CTRP2 5.3819 8.283 3.0143 3.1693
PaTu 8902 CTRP2; CTRP1 5.395 8.1355 3.898 5.1551
SUIT-2 CTRP2; CTRP1 5.4213 10.1646 2.9061 9.2515
SNU-213 CTRP2 5.7813 7.0963 3.7352 0.2801
SNU-410 CTRP2 6.3608 13.7643 1.8496 11.8456
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 5.8393 10.0094 3.312 6.8236
WT2-iPS CTRP2 -0.8052 5.1361 -1.5512 37.7143
Hs 944.T CTRP2; CTRP1 0.0237 1.8697 0.0203 34.4962
HMCB CTRP2 0.5695 2.3249 0.552 25.7834
WM983B CTRP2 0.8286 1.9828 0.8284 29.1332
A-375 CTRP2; CTRP1 0.8746 3.527 0.8098 29.044
CJM [Human melanoma] CTRP2 0.9109 1.3634 0.9109 23.2815
A2058 CTRP2 0.9972 1.4951 0.9972 22.6652
Hs 294T CTRP2 1.2083 3.2347 1.1845 26.6868
RPMI-7951 CTRP2 1.2102 2.5298 1.2087 26.5999
SK-MEL-5 CTRP2; CTRP1 1.2279 5.0667 0.9024 27.5889
IGR-37 CTRP2 1.308 2.3393 1.3078 25.9451
LOX-IMVI CTRP2 1.5074 5.1618 0.9437 21.1904
COLO 741 CTRP1 1.6515 4.6637 1.4608 50.7059
G-361 CTRP2; CTRP1 1.7904 6.0602 1.2155 24.7561
A101D CTRP2 1.8319 4.5453 1.5068 17.9394
WM88 CTRP2 1.8366 4.4922 1.6966 22.9077
MeWo CTRP2 2.0333 4.8785 1.6124 16.8879
IGR-39 CTRP2 2.686 5.5459 2.0425 13.1801
Hs 936.T CTRP2; CTRP1 2.7995 5.9194 2.3562 17.6131
COLO 800 CTRP2 2.9157 7.1937 1.5178 14.8106
WM266-4 CTRP2 2.9856 9.2268 0.5974 18.5119
Mel Ho CTRP2 3.0915 7.3548 1.6087 13.9708
SK-MEL-1 CTRP2; CTRP1 3.1336 8.9263 1.4276 20.2509
WM1799 CTRP2 3.2375 7.1237 1.8586 12.5149
K029AX CTRP2 3.3129 6.5264 2.2187 10.744
HT-144 CTRP2 3.4461 9.4654 1.4786 19.2756
WM793 CTRP2 3.5428 7.3368 2.0377 10.9869
UACC-62 CTRP2 3.5496 7.5454 1.9409 11.4003
Hs 852.T CTRP2; CTRP1 3.6937 6.4451 3.1082 12.2515
IPC-298 CTRP2 3.8782 7.5655 2.2233 9.3937
SK-MEL-28 CTRP2; CTRP1 4.0399 7.4635 3.004 11.7823
SK-MEL-30 CTRP2 4.0867 7.3457 2.5121 7.6451
COLO 829 CTRP2 4.3223 9.9899 2.0449 15.0209
IGR-1 CTRP2 4.3617 14.1141 0.0323 22.2291
MDA-MB-435S CTRP2 4.6232 8.68 2.2806 7.6173
SK-MEL-24 CTRP2 4.6255 10.1367 1.5572 10.8102
RVH-421 CTRP2 4.9923 9.5696 2.8459 10.3316
UACC-257 CTRP2 5.0957 8.8244 2.5618 5.5401
WM115 CTRP2 5.2064 12.6592 0.7551 13.0887
COLO 792 CTRP2 5.4118 10.0076 2.2102 6.5598
SK-MEL-31 CTRP2 5.6153 10.2029 2.2564 6.0432
Hs 895.T CTRP2 6.1628 11.9769 1.7763 7.2492
Mel JuSo CTRP2 6.4786 10.7898 3.3931 5.4916
SK-MEL-3 CTRP2 6.6998 16.4026 0.0122 13.3681
Hs 934.T CTRP2 7.3168 17.1103 0.9109 13.7325
Hs 688(A).T CTRP2 7.368 16.465 1.2635 12.4024
Hs 940.T CTRP2 7.4039 10.1752 4.2291 1.3564
Hs 839.T CTRP2 10.3905 22.484 -0.4691 10.0188
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 0.025 3.5219 -0.1945 30.3984
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHP-126 CTRP2 -2.841 6.1738 -4.109 50.0583
IMR-32 CTRP2 -2.1045 -0.2353 -2.1056 44.8264
CHP-212 CTRP2 -0.8194 2.427 -0.917 35.9735
SK-N-BE(2) CTRP2 -0.6632 7.3597 -1.8929 41.5869
NB1 CTRP2 -0.2389 0.3989 -0.2389 36.2311
MHH-NB-11 CTRP2 -0.0384 1.6888 -0.0404 34.9047
KP-N-SI9s CTRP2 0.1755 1.6583 0.1747 33.4783
SiMa CTRP2 0.341 1.8307 0.34 32.3782
Kelly CTRP2 0.5817 1.5348 0.5817 30.7741
NH-6 CTRP2 0.6789 2.5719 0.6495 25.0449
SK-N-FI CTRP2 0.9107 2.4139 0.8991 23.3247
SK-N-AS CTRP2 1.125 3.6786 0.9671 22.3348
KP-N-YN CTRP2 1.232 7.3845 0.1282 30.1241
SK-N-SH CTRP2 1.2385 4.6471 0.8288 22.4923
SK-N-DZ CTRP2 1.7992 3.4214 1.7419 17.1446
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 0.1035 1.9268 0.0913 29.0934
HuCC-T1 CTRP2 2.0811 4.2191 2.006 21.0578
SNU-1196 CTRP2 2.6764 5.3429 2.4074 17.7882
HuH-28 CTRP2 3.7233 5.5644 3.0727 5.9546
SNU-1079 CTRP2 3.7669 8.9901 2.0144 16.4185
SNU-869 CTRP2 3.8756 7.362 2.3224 8.9548
SNU-308 CTRP2 4.1485 7.2689 2.6026 7.1082
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-ES-1 CTRP2 -0.1878 1.5206 -0.1894 35.8967
MHH-ES-1 CTRP2 0.4264 1.3655 0.4262 26.7436
SK-N-MC CTRP2 0.5071 1.7563 0.5068 31.2713
A-673 CTRP2 0.5344 1.4895 0.5342 25.9724
SJSA-1 CTRP2 0.6602 5.7617 0.0836 32.1204
TC71 CTRP2 0.8133 1.2201 0.8133 29.2341
SaOS-2 CTRP2 1.0729 3.6404 1.007 27.7293
G-292 clone A141B1 CTRP2 1.3235 5.9388 0.7492 27.8122
HOS CTRP2 1.62 2.6044 1.617 18.2269
U2OS CTRP2; CTRP1 1.7694 4.7274 1.5751 23.5439
CAL-78 CTRP2 2.1486 7.8854 0.8901 24.8626
MG-63 CTRP2 2.2719 6.7165 1.1025 18.295
SW1353 CTRP2 3.4341 6.7911 2.205 10.5049
Hs 822.T CTRP2 6.5115 7.3397 4.9423 0.078
Hs 888.T CTRP2 8.6448 27.2481 -3.0944 22.7354
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 70 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-157 CTRP2 -1.2132 5.1837 -1.7928 43.7542
SK-BR-3 CTRP2 0.4764 11.1334 -2.2483 38.1495
DU4475 CTRP2 0.5241 1.6338 0.524 31.1579
AU565 CTRP2 0.5994 4.3169 0.3909 31.3473
BT-20 CTRP2 0.7251 4.1882 0.4055 25.7946
HCC1806 CTRP2 0.8357 2.0884 0.8325 23.8305
HMC-1-8 CTRP2 0.9331 2.3698 0.924 23.1558
CAL-51 CTRP2 0.9497 2.2246 0.949 28.3296
MDA-MB-468 CTRP2 1.1329 2.0699 1.1328 27.109
HCC38 CTRP2 1.1794 3.8818 0.9802 22.1026
ZR-75-1 CTRP2 1.2138 2.7044 0.4604 4.2079
MCF-7 CTRP2; CTRP1 1.2263 7.5866 0.0426 30.4051
CAL-85-1 CTRP2 1.5501 3.8577 1.3896 19.3104
EFM-192A CTRP2 1.8171 4.5675 1.4836 18.0773
HCC2218 CTRP2 1.9927 9.9775 -0.1941 28.8231
MDA-MB-453 CTRP2 2.1246 7.9975 0.8176 25.1842
Hs 578T CTRP2 2.5455 8.4096 1.0717 23.1126
HCC1954 CTRP2 2.6093 5.4779 1.9915 13.6136
CAMA-1 CTRP2 2.7919 12.7342 -1.3086 25.7725
BT-549 CTRP2 3.0545 6.1428 2.1491 11.7134
JIMT-1 CTRP2 3.4834 7.1557 2.5847 14.8594
HCC1395 CTRP2 3.5006 7.5584 1.89 11.7413
HCC1143 CTRP2 3.6237 7.5104 2.0251 10.8543
CAL-120 CTRP2 3.7993 5.4423 3.6012 10.0797
HDQ-P1 CTRP2 3.8381 7.0686 2.9846 12.3626
HCC1500 CTRP2 4.2653 6.7894 3.5407 9.0617
HCC202 CTRP2 4.5079 8.8298 2.1153 8.5749
KPL-1 CTRP2 4.6157 12.6517 0.9826 18.4483
MDA-MB-231 CTRP2 4.6954 9.3557 2.6937 11.5741
BT-474 CTRP2 4.8056 8.4143 3.2592 8.9939
HCC1937 CTRP2 4.8925 9.6387 2.0119 8.3129
HCC1428 CTRP2 4.9896 9.8903 1.9608 8.3633
HCC1419 CTRP2 5.2265 9.4669 2.342 6.2869
ZR-75-30 CTRP2 5.2542 8.999 2.5884 5.1706
T-47D CTRP2 5.2796 13.6108 1.0671 16.7806
MDA-MB-361 CTRP2 6.4067 20.9478 -1.6856 23.0722
BT 428 CTRP2 -0.9853 6.0181 -1.788 42.7483
BT 416 CTRP2 -0.4357 3.1143 -0.5309 37.8291
BT 145 CTRP2 0.026 2.7055 -0.0529 29.887
BT 112 CTRP2 0.0276 3.8239 -0.2611 30.6251
BT164 CTRP2 0.5586 2.5453 0.5259 25.9164
BT 286 CTRP2 0.9296 8.7769 -0.7565 33.5824
BT 245 CTRP2 1.4307 7.0105 0.4842 28.3678
BT 248 CTRP2 3 8.8277 1.3406 20.9203
BT 504 CTRP2 3.0959 6.8363 2.3195 16.9227
BT 172 CTRP2 3.2278 9.0009 1.4855 19.7931
BT 231 CTRP2 3.4056 6.8012 2.6577 14.7784
BT 239 CTRP2 3.5935 11.722 0.5248 22.3623
BT147 CTRP2 3.6863 10.6891 1.1157 20.0516
BT 232 CTRP2 3.7784 10.3991 1.3431 18.989
BT 440 CTRP2 3.779 9.5342 1.7638 17.3747
BT 271 CTRP2 4.2704 9.6635 2.1584 14.6808
BT 482 CTRP2 4.3402 15.8889 -0.871 24.954
BT 330 CTRP2 4.3445 8.2136 2.9372 11.3384
BT 187 CTRP2 4.3504 9.4393 2.3419 13.7617
BT 444 CTRP2 4.4957 9.171 2.6064 12.3624
BT 131 CTRP2 4.6088 10.4711 2.0628 14.3279
BT 333 CTRP2 4.6879 9.9571 2.3881 12.8448
BT 320 CTRP2 4.9843 5.4883 4.856 1.9828
BT 216 CTRP2 5.0876 14.2617 0.5814 18.8846
BT 422 CTRP2 5.1287 5.8712 4.8091 1.842
BT 159 CTRP2 5.2456 14.5942 0.5472 18.6849
BT 228 CTRP2 5.2907 12.921 1.4211 15.4436
BT 328 CTRP2 5.3165 10.0376 2.884 9.5403
BT 224 CTRP2 5.3429 11.8097 1.2781 10.6775
BT 179 CTRP2 5.4954 12.4662 1.0679 11.2857
BT 498 CTRP2 6.0541 21.2816 -2.134 24.7833
BT 340 CTRP2 6.5901 16.5892 0.6253 15.9228
BT 139 CTRP2 7.1213 21.2972 -1.302 20.8566
BT 359 CTRP2 8.1366 22.8695 -1.3157 19.2691
⏷ Show the Full List of 70 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 0.9875 2.7881 0.9544 22.854
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med CTRP2 -2.8188 -1.5353 -2.8188 49.926
SF539 CTRP2 -1.4728 2.0108 -1.519 44.5373
KNS-60 CTRP2 0.131 3.0191 0.0769 33.9485
SF268 CTRP2 0.1825 3.5091 0.0769 33.7726
GB-1 CTRP2 0.3843 4.5377 -0.0675 28.693
42-MG-BA CTRP2 0.4168 2.7441 0.3941 31.9465
LN-18 CTRP2 0.5692 1.3752 0.5692 25.7227
LN-229 CTRP2; CTRP1 0.5885 3.1622 0.544 30.8775
SF295 CTRP2; CTRP1 0.8143 5.2367 0.4054 30.5888
Daoy CTRP2 1.0953 3.5531 0.9605 22.4598
SF126 CTRP2 1.24 2.682 1.225 20.9846
8-MG-BA CTRP2 1.4691 3.0553 1.4357 19.4148
Hs 683 CTRP2 1.5682 4.753 1.1523 20.1738
T98G CTRP2 1.5936 6.3859 0.8894 26.498
SW1783 CTRP2 1.6569 12.7152 -2.3429 31.5119
SNU-738 CTRP2 1.8321 4.1455 1.7502 22.7369
A-172 CTRP2 1.9395 4.7047 1.765 22.3445
TM-31 CTRP2 2.1087 4.7834 1.7274 16.1928
SNU-466 CTRP2 2.5276 5.2535 1.9982 13.8231
GOS-3 CTRP2 2.5512 6.6068 1.4336 16.1348
M059K CTRP2 2.5819 5.4354 1.9806 13.7378
U-118MG CTRP2 2.6738 5.9968 2.1933 18.5835
SNU-626 CTRP2 2.7359 6.0937 2.2257 18.2838
SNB-75 CTRP2 2.9473 8.3804 1.4923 20.4892
GMS-10 CTRP2 3.0174 5.6563 2.3343 11.0152
YH-13 CTRP2 3.1428 7.4281 1.6218 13.786
SW1088 CTRP2 3.1469 8.6359 1.036 16.2967
ONS-76 CTRP2 3.1786 6.9635 1.8803 12.5668
CCF-STTG1 CTRP2 3.3216 7.5577 1.7258 12.8925
Becker CTRP2 3.4319 8.7286 1.8137 18.0221
U-251MG CTRP2 3.788 10.2321 1.4335 18.625
KALS-1 CTRP2 3.8964 7.5669 2.8143 12.8995
DK-MG CTRP2 3.9525 7.2264 2.457 8.1817
U-87MG ATCC CTRP2 4.123 8.8395 1.7959 10.7746
GaMG CTRP2; CTRP1 4.4459 7.5626 3.3486 9.4141
CAS-1 CTRP2 4.6777 9.1093 2.8004 11.171
YKG-1 CTRP2 4.9246 8.2629 2.7132 5.1584
KG-1-C CTRP2 5.2789 6.7475 4.4975 2.8558
SNU-489 CTRP2 5.3215 9.892 2.9609 9.2109
KNS-81 CTRP2 5.5271 11.3161 2.4166 11.0686
KNS-42 CTRP2 5.8792 10.3346 2.3691 5.1793
SNU-201 CTRP2 6.2156 19.8503 -1.2903 22.3949
DBTRG-05MG CTRP2 7.2077 12.4279 3.0988 5.6523
SNU-1105 CTRP2 8.4481 18.0086 0.4078 9.416
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2; CTRP1 -2.2346 0.5808 -2.2423 49.5054
JHUEM-3 CTRP2 -0.3569 3.6776 -0.6452 33.3336
HEC-151 CTRP2; CTRP1 -0.1322 1.9596 -0.1391 35.5444
RL95-2 CTRP2 0.2651 3.2008 0.1285 28.3906
MFE-296 CTRP2 0.3996 3.8475 0.2596 32.4457
HEC-108 CTRP2; CTRP1 0.6292 2.4497 0.6226 30.4802
HEC-6 CTRP2; CTRP1 0.6352 1.5637 0.6352 30.4184
ESS-1 CTRP2 0.7079 2.2706 0.7053 29.9437
JHUEM-7 CTRP2 0.9276 2.5418 0.91 23.2258
KLE CTRP2; CTRP1 1.2384 4.8506 0.9682 27.3296
JHUEM-1 CTRP2 1.2934 3.2981 1.2185 20.8223
HEC-265 CTRP2; CTRP1 1.5601 4.102 1.4654 24.5887
MFE-319 CTRP2; CTRP1 2.6046 5.5847 2.2561 18.5542
HEC-251 CTRP2; CTRP1 2.6226 5.3621 2.3432 18.183
HEC-50B CTRP2 2.9446 4.7236 2.2171 5.3713
HEC-1-B CTRP2 2.9759 6.0111 2.1317 11.9981
HEC-1-A CTRP2 2.9871 7.3894 1.9721 18.5542
HEC-59 CTRP2; CTRP1 3.4285 5.9549 3.0213 13.3162
AN3-CA CTRP2 3.9722 7.6155 2.8662 12.5046
EFE-184 CTRP2 4.0981 8.0702 2.1596 9.205
EN CTRP2 4.4457 8.0225 3.1249 10.3362
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 1.6265 4.0883 1.5385 24.1243
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
769-P CTRP2 0.2096 2.2896 0.1812 28.3938
UO-31 CTRP2 0.6866 6.2545 -0.0469 32.4276
A-498 CTRP2 1.3513 5.0352 0.8206 22.1655
BFTC-909 CTRP2 1.708 3.4675 1.6881 23.3509
ACHN CTRP2 1.7168 6.6152 0.939 25.953
786-O CTRP2 1.8156 3.321 1.6548 11.2903
KMRC-3 CTRP2 1.9103 4.7966 1.7128 22.6194
CAL-54 CTRP2 2.8592 5.9348 2.0489 12.6697
TUHR4TKB CTRP2 3.0448 6.5244 2.3924 16.7826
VMRC-RCW CTRP2; CTRP1 3.4325 6.4656 2.8257 14.0534
KMRC-20 CTRP2 3.6835 7.5191 2.6243 14.1903
VMRC-RCZ CTRP2 4.0017 7.7793 2.818 12.6281
KMRC-1 CTRP2 4.1527 8.9163 2.4155 13.9081
SNU-1272 CTRP2 4.3926 8.7156 2.0799 8.9595
Caki-2 CTRP2 4.7276 8.0448 2.6753 5.6662
TUHR10TKB CTRP2 4.8051 8.6131 3.16 9.4085
KMRC-2 CTRP2 4.8972 7.5496 3.0411 3.7654
Caki-1 CTRP2 5.0556 7.1038 4.1312 4.8292
RCC10RGB CTRP2; CTRP1 5.3285 10.5545 2.6354 10.5456
TUHR14TKB CTRP2 5.4709 14.9871 0.5367 30.45
OS-RC-2 CTRP2 5.7101 10.9025 1.9847 7.0579
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-CO-1 CTRP2; CTRP1 -1.1952 1.2658 -1.2026 42.6118
GP2d CTRP2; CTRP1 -1.1549 3.1525 -1.3018 42.6651
SNU-C5 CTRP2; CTRP1 -1.1532 4.6312 -1.5853 43.1699
COLO 320 CTRP2; CTRP1 -1.0023 3.3496 -1.1674 41.7162
SNU-175 CTRP1 -0.7067 2.7128 -0.7747 76.0174
LoVo CTRP2; CTRP1 -0.6817 1.8847 -0.6967 39.2229
SW48 CTRP2; CTRP1 0.0366 1.3017 0.0365 34.3995
LS180 CTRP2; CTRP1 0.0394 3.2469 -0.0428 34.6467
CCK-81 CTRP2 0.0846 2.1047 0.0776 34.1032
CW-2 CTRP2; CTRP1 0.0907 6.3107 -0.7122 36.3398
SNU-81 CTRP2; CTRP1 0.3147 4.5745 0.0267 33.4743
SNU-1040 CTRP1 0.3781 4.5797 0.0945 63.5005
T84 CTRP2 0.3851 4.7848 0.0541 33.1467
SNU-407 CTRP2 0.5745 3.5969 0.3864 26.3748
LS513 CTRP2; CTRP1 0.6604 1.7482 0.6603 30.2509
RKO CTRP2; CTRP1 0.688 2.6676 0.6762 30.1067
KM12 CTRP2; CTRP1 0.7493 3.0942 0.7171 29.7673
DLD-1 CTRP2; CTRP1 0.7745 1.6825 0.7745 29.4921
LS1034 CTRP2 0.8177 1.6302 0.8176 23.9478
HCT 15 CTRP2 0.8619 1.4868 0.8619 23.6319
SNU-C4 CTRP2; CTRP1 0.9795 2.9802 0.9622 28.1868
CL-40 CTRP1 0.9925 5.7216 0.458 56.8406
LS411N CTRP2; CTRP1 1.023 2.3636 1.0217 27.8438
HCT 116 CTRP2; CTRP1 1.0896 3.0516 1.0721 27.4553
CL-34 CTRP1 1.1051 4.1578 0.9673 57.3145
SW480 CTRP1 1.3885 6.6057 0.5894 52.8733
SNU-C1 CTRP2 1.444 2.8196 1.4281 19.5303
SW1417 CTRP2 1.4872 4.062 1.3933 25.0707
MDST8 CTRP2; CTRP1 1.4877 6.2647 0.8175 27.0699
SW620 CTRP2; CTRP1 1.6357 4.13 1.5422 24.082
SNU-1033 CTRP2 1.7411 8.0616 0.391 27.7354
RCM-1 [Human ESC] CTRP2; CTRP1 1.8159 4.8852 1.5892 23.349
SW948 CTRP2; CTRP1 1.8439 4.1665 1.7598 22.6658
SNU-C2A CTRP2; CTRP1 1.846 5.4808 1.4612 23.711
CL-11 CTRP2 1.944 5.7815 1.4746 23.3667
HT-55 CTRP2; CTRP1 1.9455 5.138 1.6666 22.674
SNU-61 CTRP2; CTRP1 2.0297 5.0662 1.7773 22.021
HCT 8 CTRP2; CTRP1 2.1835 4.9723 1.9688 20.8657
LS123 CTRP2; CTRP1 2.4909 9.6113 0.4723 25.3428
NCI-H716 CTRP2 2.5522 5.3296 1.9932 13.7718
SNU-503 CTRP2 2.6417 9.2954 0.2439 20.7856
COLO205 CTRP2; CTRP1 2.7219 4.0166 2.7049 16.5991
HT115 CTRP2; CTRP1 2.7953 4.6662 2.7008 16.3767
SW1116 CTRP2 2.8218 10.6595 0.3066 25.0112
HCC-56 CTRP2 3.2321 6.5752 2.1179 11.3903
C2BBe1 CTRP2; CTRP1 3.3704 6.511 2.7418 14.5466
NCI-H747 CTRP2 4.0178 9.9633 1.7787 16.7602
OUMS-23 CTRP2 4.1302 6.7951 3.4029 9.9523
COLO201 CTRP2 4.1926 6.5973 3.5556 9.1841
SW403 CTRP1 4.2141 7.2879 3.2572 21.9288
HT-29 CTRP2; CTRP1 4.2243 5.2981 4.1089 6.9574
NCI-H508 CTRP2; CTRP1 5.3757 8.4984 3.7014 6.0142
COLO 678 CTRP2; CTRP1 5.9391 15.2377 0.7897 16.5152
⏷ Show the Full List of 53 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-398 CTRP2; CTRP1 -1.0289 4.366 -1.3883 42.276
JHH-5 CTRP2 0.4628 3.4645 0.2927 27.1042
Li-7 CTRP2 0.5482 2.984 0.5156 31.1059
HLF CTRP2 0.5784 2.4494 0.5711 30.8205
SNU-878 CTRP2 0.8837 2.1641 0.883 28.7681
HuH-1 CTRP2 1.6005 3.9431 1.4243 19.0104
PLC/PRF/5 CTRP2 1.7515 3.2351 1.715 17.4089
JHH-4 CTRP2 1.785 3.3242 1.7746 22.8072
SNU-182 CTRP2 2.2025 5.9815 1.3547 17.4411
SNU-449 CTRP2; CTRP1 2.3995 4.1593 2.3529 18.8433
SNU-423 CTRP2 2.9628 6.2132 2.4255 16.8864
HuH-6 CTRP2 3.0349 9.9685 0.2778 19.6629
JHH-1 CTRP2 3.3193 6.014 2.4695 9.6275
JHH-2 CTRP2 3.6269 6.6664 2.9451 13.0669
SNU-761 CTRP2 3.6649 13.5165 -0.2923 24.8069
Hep 3B2.1-7 CTRP2 3.8148 7.8184 2.6164 13.896
SK-HEP-1 CTRP2 5.6053 10.017 3.1271 7.9973
SNU-475 CTRP2 5.6455 13.2718 0.7825 12.1868
JHH-6 CTRP2; CTRP1 5.8999 7.3933 4.6252 1.3968
Hep-G2 CTRP2; CTRP1 6.363 10.9554 3.2319 6.315
SNU-387 CTRP2 7.8897 9.5171 4.6862 0.1303
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 162 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1781 CTRP1 -3.3955 10.0096 -5.8206 69.3318
NCI-H1876 CTRP1 -2.7101 2.5341 -2.877 83.5186
NCI-H1963 CTRP1 -2.4219 1.1103 -2.4496 88.3498
NCI-H524 CTRP2 -2.1546 9.6007 -4.7133 47.2343
NCI-H1048 CTRP1 -1.8612 1.416 -1.887 85.9132
COR-L279 CTRP2; CTRP1 -1.8104 1.273 -1.8291 46.7131
NCI-H2228 CTRP2 -1.645 8.044 -3.1994 46.9438
NCI-H1155 CTRP2 -1.4717 1.5669 -1.4936 44.4805
NCI-H596 CTRP1 -1.4523 1.5753 -1.474 83.9473
Lu-99 CTRP2; CTRP1 -1.4474 0.7691 -1.4501 44.2749
NCI-H1734 CTRP2 -1.4038 1.8639 -1.4723 40.0278
NCI-H1105 CTRP2; CTRP1 -1.2199 2.8328 -1.3296 43.0104
SK-LU-1 CTRP2; CTRP1 -1.0291 7.7694 -2.4365 43.7694
COR-L23 CTRP1 -1.0107 3.8348 -1.2589 73.9256
NCI-H2286 CTRP2; CTRP1 -0.9801 2.6055 -1.0521 41.3544
NCI-H1694 CTRP2; CTRP1 -0.8811 1.5525 -0.8901 40.5294
NCI-H1930 CTRP1 -0.8429 7.4175 -2.1074 65.366
NCI-H2081 CTRP2; CTRP1 -0.7193 4.4817 -1.0775 40.3299
NCI-H1568 CTRP2; CTRP1 -0.6829 0.9048 -0.6833 39.1852
SCLC-21H CTRP1 -0.6316 0.8553 -0.6319 81.8422
NCI-H1836 CTRP1 -0.363 5.5158 -0.9583 66.4533
HARA [Human squamous cell lung carcinoma] CTRP2; CTRP1 -0.312 2.6183 -0.3538 36.8505
NCI-H1341 CTRP2 -0.2344 2.3999 -0.2938 31.6757
LUDLU-1 CTRP2 -0.2227 3.975 -0.4332 36.7596
COLO 668 CTRP2; CTRP1 -0.0707 2.5565 -0.0992 35.2058
HCC1359 CTRP1 0.0876 4.6241 -0.2318 65.5591
NCI-H211 CTRP2 0.2057 2.3241 0.1746 28.4314
NCI-H2171 CTRP2 0.2381 2.0038 0.2261 28.1313
NCI-H2141 CTRP1 0.2499 8.5459 -1.3748 58.9363
HCC78 CTRP2; CTRP1 0.2607 3.0301 0.212 33.0697
NCI-H2087 CTRP2 0.284 8.3187 -1.2473 36.8899
NCI-H2023 CTRP2; CTRP1 0.3054 5.3008 -0.1677 34.0919
NCI-H1944 CTRP2; CTRP1 0.3738 2.4036 0.364 32.1892
PC-14 CTRP2 0.3862 3.6417 0.2761 32.4375
HCC44 CTRP2; CTRP1 0.394 1.839 0.3931 32.0253
NCI-H526 CTRP2 0.4226 1.4581 0.4223 26.771
NCI-H1623 CTRP2 0.4657 3.7741 0.2282 27.3325
EBC-1 CTRP2; CTRP1 0.4753 3.3492 0.4071 31.7083
DMS 53 CTRP2 0.4926 3.3379 0.4265 31.5862
NCI-H2009 CTRP2; CTRP1 0.5128 4.457 0.2679 32.037
DMS 79 CTRP2 0.5232 7.2504 -0.9307 31.1236
NCI-H1184 CTRP2 0.5526 3.3409 0.4137 26.3486
NCI-H460 CTRP2; CTRP1 0.5551 1.3696 0.5551 30.951
NCI-H1437 CTRP1 0.5639 2.9099 0.5367 64.9628
NCI-H2073 CTRP1 0.5801 5.698 0.0159 60.1409
NCI-H2170 CTRP2 0.61 2.8646 0.548 25.6559
MOR/CPR CTRP2 0.6257 1.2925 0.6257 25.3192
HCC1438 CTRP2 0.6507 1.3242 0.6507 30.3154
HCC1588 CTRP2 0.6526 2.6165 0.6183 25.2507
NCI-H82 CTRP1 0.6587 1.9494 0.6581 64.8835
NCI-H1573 CTRP1 0.7316 9.056 -1.0806 56.0019
NCI-H23 CTRP1 0.7384 2.8129 0.722 63.0918
HCC827 CTRP2; CTRP1 0.7627 5.1971 0.3599 30.9062
LCLC-97TM1 CTRP2; CTRP1 0.7868 2.9234 0.7665 29.4781
NCI-H1373 CTRP2; CTRP1 0.7895 2.719 0.7782 29.4301
SK-MES-1 CTRP2 0.8313 3.1782 0.7414 24.1776
NCI-H838 CTRP2 0.8493 1.363 0.8493 23.7219
NCI-H2110 CTRP2; CTRP1 0.8556 3.3679 0.8059 29.1191
NCI-H292 CTRP2 0.9303 3.0184 0.8694 23.3643
COLO 699 CTRP2; CTRP1 0.9608 5.0411 0.6176 29.4101
NCI-H358 CTRP2; CTRP1 0.9637 3.8923 0.8578 28.5902
HCC15 CTRP2; CTRP1 1.0059 4.5835 0.7766 28.7287
NCI-H1339 CTRP2 1.0245 2.2433 1.0207 22.4839
DV-90 CTRP2; CTRP1 1.0327 4.5373 0.8156 28.5096
NCI-H1666 CTRP2; CTRP1 1.0731 10.1339 -1.1956 34.1909
A-549 CTRP2; CTRP1 1.1193 2.4957 1.1175 27.2055
DMS 273 CTRP2; CTRP1 1.1449 3.4378 1.1033 27.1683
EPLC-272H CTRP1 1.1514 3.2506 1.1245 57.5497
HOP-62 CTRP2 1.1575 7.8408 -0.1317 31.1436
Lu-65 CTRP2; CTRP1 1.1589 5.575 0.684 28.5514
DMS 114 CTRP2 1.1589 3.5808 1.1044 27.119
NCI-H69 CTRP2 1.1779 5.2699 0.5498 23.77
NCI-H446 CTRP2 1.187 4.1381 1.0589 27.1827
NCI-H510A CTRP2 1.2071 2.7282 1.1882 21.2338
NCI-H209 CTRP2 1.2311 8.0623 -0.1441 30.9484
Sq-1 CTRP2; CTRP1 1.2366 3.9395 1.1429 26.7356
NCI-H647 CTRP2 1.2514 3.3617 1.1635 21.1705
NCI-H1838 CTRP2 1.2986 3.8878 1.1086 21.2174
VMRC-LCD CTRP2; CTRP1 1.3388 3.4399 1.306 25.8497
NCI-H520 CTRP2 1.3497 2.8116 1.3457 25.6805
COR-L51 CTRP2; CTRP1 1.4156 4.0611 1.3167 25.564
HCC2108 CTRP2; CTRP1 1.4168 3.8938 1.3414 25.4754
RERF-LC-A1 CTRP2 1.4288 4.4437 1.0995 20.8258
LK2 CTRP2 1.4691 2.5544 1.465 19.3087
NCI-H522 CTRP2; CTRP1 1.4942 3.7508 1.4405 24.8869
NCI-H2029 CTRP2; CTRP1 1.5051 4.1201 1.4037 24.9776
NCI-H1793 CTRP2; CTRP1 1.5081 7.1592 0.5098 28.0462
NCI-H322 CTRP2 1.56 5.1133 1.0179 20.7322
NCI-H1703 CTRP2 1.5853 3.8691 1.4253 19.0575
HCC366 CTRP2 1.6067 4.2922 1.3382 19.3219
HCC1195 CTRP2; CTRP1 1.6106 5.949 1.0577 25.8588
COR-L95 CTRP2 1.6398 6.164 0.691 21.7945
HCC33 CTRP1 1.6448 4.7637 1.4313 50.777
NCI-H810 CTRP2; CTRP1 1.7447 5.2436 1.4189 24.1718
NCI-H1581 CTRP2 1.8796 4.7765 1.6839 22.8171
SHP-77 CTRP2; CTRP1 1.88 4.3693 1.766 22.5289
NCI-H1975 CTRP1 1.9372 5.0567 1.6789 47.2564
NCI-H1385 CTRP2 1.9805 5.2177 1.6834 22.5067
NCI-H1299 CTRP2; CTRP1 1.9895 4.2905 1.8969 21.727
HOP-92 CTRP2 2.0116 10.6399 -0.4796 29.5907
LCLC-103H CTRP2; CTRP1 2.0178 3.5892 2.0015 21.2786
NCI-H1650 CTRP2 2.0946 5.7713 1.6417 22.3122
SBC-5 CTRP2 2.1323 6.082 1.2389 18.1236
Calu-3 CTRP2; CTRP1 2.1751 5.1703 1.9086 21.1064
NCI-H2405 CTRP2; CTRP1 2.2161 6.0174 1.6911 21.7721
T3M-10 CTRP2; CTRP1 2.2239 6.6603 1.4655 22.5765
CAL-12T CTRP2; CTRP1 2.2273 4.7933 2.0584 20.413
HCC1833 CTRP2; CTRP1 2.3077 5.8416 1.85 20.9207
NCI-H1755 CTRP2; CTRP1 2.3092 6.9905 1.4274 22.4723
RERF-LC-MS CTRP2 2.3382 5.0087 2.1285 19.8206
NCI-H2196 CTRP2 2.4073 6.6224 1.2818 17.1701
NCI-H650 CTRP2; CTRP1 2.4264 5.3312 2.1381 19.5168
KNS-62 CTRP2; CTRP1 2.4384 5.0621 2.2242 19.1712
LXF 289 CTRP2; CTRP1 2.4466 5.647 2.0643 19.7251
NCI-H2122 CTRP2; CTRP1 2.6511 6.0173 2.1615 18.7674
EKVX CTRP2 2.6543 7.5135 1.574 20.9661
NCI-H2126 CTRP2; CTRP1 2.6583 5.8147 2.2393 18.4577
NCI-H441 CTRP2; CTRP1 2.6982 7.6419 1.5645 20.8821
NCI-H1092 CTRP2 2.7018 6.5624 1.6046 14.9993
HCC95 CTRP2 2.7766 6.1323 2.2555 18.0557
NCI-H841 CTRP2; CTRP1 2.8254 7.6686 1.6843 20.0867
LOU-NH91 CTRP2 2.8426 5.7665 2.4554 17.1196
NCI-H889 CTRP2 2.8475 23.4828 -5.9632 37.2353
NCI-H661 CTRP2; CTRP1 2.9211 8.1755 1.5582 20.3096
NCI-H1435 CTRP1 2.9612 5.9797 2.5095 34.9987
Calu-6 CTRP2; CTRP1 2.9853 5.6764 2.6403 16.0181
COR-L105 CTRP2 3.0332 5.991 2.1981 11.5579
SW1573 CTRP2 3.1116 7.0912 2.2288 17.2306
DMS 454 CTRP2 3.1307 9.3234 1.239 20.9617
ChaGo-K-1 CTRP2; CTRP1 3.2166 5.8622 2.8269 14.6522
NCI-H1355 CTRP2; CTRP1 3.2357 6.4562 2.6217 15.3778
LC-1/sq-SF CTRP2; CTRP1 3.2425 7.3231 2.2641 16.7459
NCI-H727 CTRP2; CTRP1 3.3614 8.4817 1.8596 18.0201
NCI-H2030 CTRP2; CTRP1 3.4303 8.0068 2.1476 16.719
NCI-H196 CTRP2 3.4762 7.0729 2.1063 10.8409
NCI-H1395 CTRP2 3.5239 8.3862 2.0646 16.8117
NCI-H2444 CTRP2 3.5523 6.7393 2.8365 13.6897
NCI-H1915 CTRP2; CTRP1 3.587 7.2285 2.6582 14.3015
NCI-H1693 CTRP2 3.6271 10.4273 0.5781 17.0645
RERF-LC-KJ CTRP1 3.6663 8.3932 2.201 31.9187
HCC4006 CTRP2; CTRP1 3.8081 7.0841 2.9473 12.5876
RERF-LC-Ad2 CTRP2 3.9113 7.822 2.1241 9.7649
NCI-H2106 CTRP2 4.0954 8.7792 2.4283 13.988
BEN CTRP2; CTRP1 4.1021 8.5953 2.5237 13.5855
NCI-H2291 CTRP2 4.1171 11.7966 0.3125 17.0381
NCI-H2172 CTRP2; CTRP1 4.262 7.6226 3.1445 10.6794
NCI-H226 CTRP2 4.3726 7.4502 3.3331 9.6478
COR-L88 CTRP1 4.3787 9.5074 2.3342 27.2791
NCI-H1563 CTRP2 4.5879 19.229 -2.3248 28.0088
HCC2935 CTRP2; CTRP1 4.617 10.6506 1.9807 14.6386
IA-LM CTRP2 4.6208 8.3057 2.4648 6.7994
SW1271 CTRP2 4.6815 14.3469 0.1936 21.0232
Calu-1 CTRP2 4.723 12.5315 1.1355 17.6633
NCI-H1792 CTRP2; CTRP1 4.8404 7.8626 3.564 7.6489
NCI-H1869 CTRP2 5.0263 8.1026 3.6076 7.082
HCC2279 CTRP2 5.2192 8.8627 2.63 5.0451
NCI-H2085 CTRP2 5.2812 8.6808 1.9395 2.751
RERF-LC-Ad1 CTRP2 5.3879 6.4664 3.8096 0.2816
NCI-H2342 CTRP2; CTRP1 6.3916 14.4112 1.5528 12.9266
NCI-H3255 CTRP1 6.6666 20.4312 -1.2238 31.5991
HCC1171 CTRP2 6.9498 15.4444 0.6473 10.6041
Hs 888.Lu CTRP2 5.6092 13.0683 0.8558 11.9543
⏷ Show the Full List of 162 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 -0.1476 6.0851 -1.1751 34.1871
H-STS CTRP2 0.9593 1.4594 0.9593 22.9362
SYO-1 CTRP2 1.1223 2.4816 1.1207 27.1847
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 0.9771 6.2728 0.262 30.5183
OVKATE CTRP1 -3.3852 2.8736 -3.6512 83.5545
RMUG-S CTRP1 -0.6474 6.2283 -1.487 66.5049
OC 314 CTRP2 -0.4729 1.0895 -0.4734 37.7889
TYK-nu CTRP2; CTRP1 -0.3492 3.2987 -0.462 37.3098
A2780 CTRP1 -0.329 1.952 -0.3389 75.9459
TOV-112D CTRP2 -0.0053 2.8864 -0.1112 30.2071
JHOC-5 CTRP2; CTRP1 0.0655 3.2755 -0.0185 34.4792
HEY A8 CTRP2; CTRP1 0.1401 2.7651 0.1063 33.8222
Caov-3 CTRP2; CTRP1 0.4069 2.2957 0.4005 31.9581
COV434 CTRP2; CTRP1 0.4896 5.3643 0.0155 32.9069
RMG-I CTRP2; CTRP1 0.5659 7.1616 -0.4989 34.116
MCAS CTRP2 0.6978 1.9026 0.6975 30.0033
OV56 CTRP2 0.7612 3.6691 0.6725 29.8776
ES2 CTRP2 0.9021 5.2141 0.2724 25.7142
SNU-119 CTRP2 0.9834 5.3554 0.3094 25.3122
OVTOKO CTRP2 1.0809 6.286 0.0536 25.9631
OV7 CTRP2; CTRP1 1.0823 5.2235 0.7015 28.7371
OVISE CTRP2 1.1475 2.7747 1.1229 21.6803
IGROV-1 CTRP2; CTRP1 1.2357 4.2442 1.093 26.9091
OVK18 CTRP2; CTRP1 1.2822 4.3676 1.1206 26.6655
DOV13 CTRP2 1.5597 3.5271 1.4676 18.9844
EFO-27 CTRP2; CTRP1 1.6474 3.8519 1.5914 23.876
FU-OV-1 CTRP2 1.7048 6.098 1.1098 25.3893
JHOS-4 CTRP1 1.7236 3.6638 1.6901 49.8033
OV-90 CTRP2; CTRP1 1.9102 4.6571 1.7433 22.5127
OVCAR-5 CTRP2 2.0694 6.3847 1.4026 23.2551
OAW42 CTRP2; CTRP1 2.1983 4.7888 2.0279 20.6106
OVCAR-8 CTRP2; CTRP1 2.2161 3.574 2.2064 19.9379
SK-OV-3 CTRP2; CTRP1 2.2423 6.291 1.6228 21.946
JHOM-1 CTRP2; CTRP1 2.5089 6.9508 1.6547 21.0664
JHOS-2 CTRP2 2.7914 6.0388 1.9334 13.349
SNU-840 CTRP2; CTRP1 3.0799 6.6187 2.3918 16.6884
COV362 CTRP2; CTRP1 3.205 8.6019 1.6488 19.2294
ONCO-DG-1 CTRP2 3.2239 6.2187 2.2798 10.7026
SNU-8 CTRP2 3.5159 6.6443 2.8389 13.7772
OAW28 CTRP2 3.5586 7.8845 2.3318 15.6681
OVCAR-4 CTRP2; CTRP1 3.7598 7.654 2.6384 13.9435
COV644 CTRP2; CTRP1 4.8337 8.8057 3.0894 9.6431
EFO-21 CTRP2; CTRP1 4.845 7.5901 3.7033 7.0585
COV318 CTRP1 5.0178 10.2932 2.5061 23.2145
Kuramochi CTRP2 5.0678 7.7941 3.0405 3.5046
OVMANA CTRP1 5.4992 11.1597 2.4722 21.387
OVSAHO CTRP2 5.9493 9.9775 3.4104 6.2346
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 1.3526 5.1865 1.0067 26.8357
Yamato-SS CTRP2 3.6726 8.4879 2.1624 16.0588
KYM-1 CTRP2 -1.5079 0.687 -1.5103 44.6766
G-401 CTRP2; CTRP1 0.199 3.6295 0.0777 33.7133
A-204 CTRP2 0.7158 4.4027 0.4997 30.6033
TE 441.T CTRP2 0.8938 2.741 0.8603 23.5247
SK-UT-1 CTRP2 0.9427 3.939 0.8283 28.7588
TTC-709 CTRP2 0.9996 3.5 0.9446 28.1798
G-402 CTRP2 1.0625 3.6042 0.9148 22.7424
Rh41 CTRP2 1.1513 2.2963 1.1509 26.9878
SW982 CTRP2 1.3137 3.9129 1.2289 26.193
GCT CTRP2 1.3553 3.638 1.3057 25.7967
HT-1080 CTRP2; CTRP1 1.6365 5.8001 1.1342 25.5108
BT-16 CTRP2 1.6748 2.8983 1.6729 23.5116
TE 617.T CTRP2 1.706 3.1772 1.673 17.7209
Tm87-16 CTRP2 1.7261 5.7938 1.2336 24.8862
RKN CTRP2; CTRP1 2.2336 4.8043 2.0628 20.3778
MES-SA CTRP2 2.2805 5.2482 2.0023 20.4489
Hs 729.T CTRP2 2.4005 5.8772 1.6045 15.8323
RD CTRP2 3.4309 8.3945 1.9689 17.4192
Rh18 CTRP2 3.4649 4.9343 3.373 11.9174
SK-LMS-1 CTRP2 3.9098 9.4079 1.3311 13.2704
BT-12 CTRP2 4.9351 7.3078 3.9237 5.9476
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 3.9737 16.9454 -2.382 26.0532
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP1 -2.3714 0.2783 -2.3759 91.7435
NCI-H28 CTRP2; CTRP1 1.057 3.4351 1.0113 27.767
MPP 89 CTRP2 2.4797 5.1166 2.0019 13.9498
IST-Mes1 CTRP2 2.6749 5.4633 2.066 13.1129
NCI-H2052 CTRP2; CTRP1 3.6431 7.7528 2.4768 14.8798
NCI-H2452 CTRP2 4.9664 12.7805 1.2196 16.8481
JL-1 CTRP2 5.5515 9.4148 2.5902 4.715
ACC-MESO-1 CTRP2 5.9185 9.9095 3.421 6.2414
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
22Rv1 CTRP2 0.9978 3.587 0.8481 23.2116
NCI-H660 CTRP2 1.5743 8.4473 0.0543 29.2992
DU145 CTRP2 2.5398 5.7349 1.8099 14.5738
LNCaP clone FGC CTRP2 2.8038 5.6817 2.1051 12.5835
PaCa-3 CTRP2; CTRP1 2.9573 5.9373 2.5204 16.5449
VCaP CTRP2 3.5008 7.0519 2.6482 14.5642
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 -0.4414 4.5302 -0.9654 34.6687
YD-15 CTRP2 0.3326 1.5783 0.3313 27.4175
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-5 CTRP2 -2.376 0.5515 -2.3954 46.7969
OCUM-1 CTRP2 -0.9392 5.6047 -1.6127 42.2772
HGC-27 CTRP2 -0.8676 2.6768 -0.9405 40.6156
SNU-1 CTRP2 -0.2146 2.6526 -0.3023 31.6347
NCI-N87 CTRP2 0.1869 2.783 0.1083 28.7375
23132/87 CTRP2 0.2364 1.3745 0.2364 33.0706
AGS CTRP2; CTRP1 0.8142 4.847 0.5067 30.2562
SNU-668 CTRP2 0.875 2.3305 0.8659 23.5711
SNU-601 CTRP2 0.8973 2.9939 0.8768 28.744
GSS CTRP2 0.9278 1.6761 0.9278 28.4728
SNU-16 CTRP2 0.9294 1.5548 0.9294 28.462
ECC12 CTRP2 1.0097 1.6635 1.0097 27.9278
NUGC-3 CTRP2 1.0271 2.1262 0.5869 4.003
SNU-719 CTRP2 1.4054 6.8223 0.1683 24.5324
IM95 CTRP2 1.5396 4.35 1.4021 24.8725
SNU-620 CTRP2 1.5879 3.5135 1.5602 24.1757
NCC-StC-K140 CTRP2 2.3483 7.1884 0.9638 18.6607
Hs 746.T CTRP2 2.8315 6.1058 1.9435 13.1968
LMSU CTRP2 3.6216 6.8701 2.3394 9.459
MKN74 CTRP2; CTRP1 3.8432 7.1326 2.9608 12.4446
MKN1 CTRP2 3.8591 8.2633 2.4501 14.457
MKN7 CTRP2; CTRP1 3.9127 9.786 1.7674 17.0472
NUGC-4 CTRP2; CTRP1 3.9922 6.6376 3.3339 10.5789
GSU CTRP2 4.0834 6.2243 3.6076 9.2616
HuG1-N CTRP2 4.4877 7.9795 2.523 6.7896
KE-39 CTRP2 4.5656 10.6836 1.9189 14.9938
SNU-216 CTRP2 4.7096 10.0766 2.3477 12.9639
SH-10-TC CTRP2; CTRP1 4.8524 6.4379 4.2772 4.6584
KATO III CTRP2 5.156 8.1752 2.9175 3.9006
MKN45 CTRP2 6.4884 7.8387 4.7463 0.4806
Fu97 CTRP2; CTRP1 6.6154 10.6916 3.533 4.74
SNG-M CTRP2; CTRP1 1.1711 2.606 1.1684 26.8635
SNU-685 CTRP2 2.6146 4.8326 2.2547 12.5103
SNU-1077 CTRP2 4.4859 7.8998 3.2223 9.8438
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 0.7928 2.4932 0.7734 24.1951
CGTH-W-1 CTRP2 0.8699 3.3319 0.8243 29.0103
CAL-62 CTRP2 1.0713 2.5936 1.0678 27.5303
TT CTRP2 1.0934 2.9692 1.0482 22.1415
FTC-238 CTRP2 1.1393 1.8946 1.1392 21.6508
BHT-101 CTRP2 1.149 2.726 1.128 21.6563
8305C CTRP2 1.1675 4.4137 0.9874 27.4901
8505C CTRP2 1.1993 4.9558 0.6838 23.1817
ML-1 [Human leukemia] CTRP2 1.3084 10.2695 -1.0167 33.0476
FTC-133 CTRP2 2.0197 4.9896 1.5576 17.1503
B-CPAP CTRP2 2.6981 5.6067 2.3508 17.9299
TT2609-C02 CTRP2 4.2138 10.1403 1.2212 13.0946
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-10B CTRP2 -2.0741 6.7484 -3.4887 46.2179
HSC-4 CTRP2 0.3035 3.2048 0.1693 28.1082
CAL-33 CTRP2 0.4073 3.795 0.2761 32.366
SCC-4 CTRP2 0.5305 3.7546 0.4142 31.5007
HSC-3 CTRP2 0.7709 3.5078 0.618 24.8432
CAL-27 CTRP2 0.7954 1.6256 0.7953 24.1072
BHY CTRP2 0.8673 6.6124 0.0251 31.6113
FaDu CTRP2 0.8751 3.7068 0.6892 24.2232
HSC-2 CTRP2; CTRP1 0.9154 3.8342 0.8145 28.8945
BICR 22 CTRP2 0.9742 2.2716 0.9689 22.8485
SNU-1076 CTRP2 0.9806 4.9209 0.6699 29.1706
PE/CA-PJ49 CTRP2 1.2087 2.2798 1.2065 21.1621
Detroit 562 CTRP2 1.2182 4.8459 0.7415 22.897
PE/CA-PJ34 (clone C12) CTRP2 1.2216 3.6101 1.086 21.5613
PE/CA-PJ15 CTRP2 1.362 5.3144 0.7314 22.4828
PE/CA-PJ41 (clone D2) CTRP2 1.3789 2.7652 1.364 19.992
BICR 6 CTRP2 1.4049 2.8048 1.3886 19.8113
BICR 18 CTRP2 1.4559 2.961 1.4304 19.4804
SNU-1214 CTRP2 1.7415 6.0107 0.8612 20.8095
SNU-899 CTRP2 1.7626 5.6889 1.0144 20.1282
SCC-9 CTRP2; CTRP1 2.0102 6.3881 1.3377 23.664
SNU-1066 CTRP2 2.2944 5.7141 1.5636 16.3078
BICR 56 CTRP2 2.7084 6.4346 2.0693 18.949
SCC-25 CTRP2 2.8832 5.2461 2.6607 16.2474
BICR 31 CTRP2 3.0068 6.926 1.7335 13.6428
BICR 16 CTRP2 3.3715 7.5059 2.3153 16.2094
YD-8 CTRP2 4.543 8.6997 2.8819 11.124
SNU-46 CTRP2 4.8366 11.4591 1.0649 12.5095
SNU-1041 CTRP2 6.8517 14.3957 1.9027 10.8358
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-1 CTRP2 -0.0583 2.9224 -0.1735 30.6185
5637 CTRP2; CTRP1 0.0338 2.6651 0.0024 34.5208
RT-4 CTRP2; CTRP1 0.1918 1.4994 0.1915 33.3682
JMSU-1 CTRP2 0.1935 1.1433 0.1935 33.3557
UM-UC-3 CTRP2; CTRP1 0.4109 1.5637 0.4108 31.9104
RT-112 CTRP2 0.6001 1.5387 0.6001 30.6517
VM-CUB-1 CTRP2 0.6939 1.5676 0.6939 30.0279
647V CTRP2 0.6971 1.2068 0.6971 24.8092
TCCSUP CTRP2 0.7643 3.9175 0.519 25.2364
639V CTRP2 0.8125 2.4355 0.8086 29.2525
J82 CTRP2 0.8515 4.236 0.6795 29.5578
CAL-29 CTRP2 0.8881 2.8897 0.8723 28.7894
BFTC-905 CTRP2 1.0147 3.3265 0.9763 28.0234
KMBC-2 CTRP2; CTRP1 1.2895 6.3622 0.5693 28.5242
253J CTRP2 1.4976 2.6632 1.4966 24.6871
HT-1376 CTRP2; CTRP1 1.7896 5.5908 1.3666 24.2203
U-BLC1 CTRP2 1.9886 4.1039 1.9231 21.6399
KU-19-19 CTRP2 2.1661 7.0806 0.831 19.7102
T24 CTRP2 2.2018 6.1816 1.2678 17.8047
253J-BV CTRP2 2.2563 4.4098 2.1644 19.9512
SCaBER CTRP2 2.6463 5.3193 2.0963 13.069
BC-3C CTRP2 3.0091 6.6936 1.846 13.1479
SW1710 CTRP2 3.9899 8.3521 2.534 13.8067
HT-1197 CTRP2 4.3361 9.2502 2.4219 13.4682
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 2.0608 3.6304 1.9898 15.3271

References

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2 Synthesis, structure-affinity relationships, and biological activities of ligands binding to retinoic acid receptor subtypes. J Med Chem. 1995 Dec 22;38(26):4993-5006.
3 ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis. Blood. 2004 Jan 1;103(1):194-207.