Details of the Drug

General Information of Drug (ID: DM8Y2RU)

Drug Name
Cenegermin
Synonyms cenegermin; Cenegermin [INN]; UNII-B6E7K36KT8; B6E7K36KT8; Human beta-nerve growth factor (beta-ngf)-(1-118)- peptide (non-covalent dimer) produced in escherichia coli nerve growth factor
Indication
Disease Entry ICD 11 Status REF
Neurotrophic keratitis 9A74 Approved [1]
Affected Organisms
Humans and other mammals
ATC Code
S01XA24: Cenegermin
S01XA: Other ophthalmologicals
S01X: OTHER OPHTHALMOLOGICALS
S01: OPHTHALMOLOGICALS
S: SENSORY ORGANS
Drug Type
Antibody
Cross-matching ID
UNII
B6E7K36KT8
DrugBank ID
DB13926
TTD ID
D02KUO

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Low-affinity nerve growth factor receptor (NGFR) TTEDJN4 TNR16_HUMAN Agonist [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Neurotrophic keratitis
ICD Disease Classification 9A74
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Low-affinity nerve growth factor receptor (NGFR) DTT NGFR 5.08E-01 0.38 0.37
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 2018 FDA drug approvals.Nat Rev Drug Discov. 2019 Feb;18(2):85-89.