Details of the Drug

General Information of Drug (ID: DM92LH2)

Drug Name
Pentamycin
Synonyms
FemiFect; Pentamycin; LMV-602; Pentamycin vaginal tablets (vaginitis); Pentamycin, Necura; Pentamycin, Shogoo; Pruri-Ex; SPK-0602; N-Pent, Necura; N-Pent, Shogoo; Pentamycin vaginal tablets (vaginitis), Lumavita
Indication
Disease Entry ICD 11 Status REF
Vulvovaginitis GA02.0 Approved [1]
ATC Code
G01AA11: Pentamycin
G01AA: Antibiotics
G01A: ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
G01: GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
G: GENITO URINARY SYSTEM AND SEX HORMONES
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C35H58O12
Canonical SMILES
CCCCCC(C1C(CC(CC(CC(CC(CC(C(C(C(=CC=CC=CC=CC=CC(C(OC1=O)C)O)C)O)O)O)O)O)O)O)O)O
InChI
InChI=1S/C35H58O12/c1-4-5-11-16-29(41)32-30(42)20-26(38)18-24(36)17-25(37)19-27(39)21-31(43)34(45)33(44)22(2)14-12-9-7-6-8-10-13-15-28(40)23(3)47-35(32)46/h6-10,12-15,23-34,36-45H,4-5,11,16-21H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,22-14+/t23-,24+,25-,26+,27-,28+,29-,30+,31-,32-,33-,34-/m1/s1
InChIKey
AGJUUQSLGVCRQA-SWOUQTJZSA-N
Cross-matching ID
PubChem CID
5282200
CAS Number
-98-6
UNII
1JB340D58S
DrugBank ID
DB13571
TTD ID
D0A9ZX
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug

Molecular Interaction Atlas of This Drug


Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Ribosomal 23S RNA methyltransferase Erm (erm) DEW6V07 A0A5N1AHF6_CORAY Substrate [2]
Ribosomal 23S RNA methyltransferase Erm (erm) DEA65D8 A0A381KDL2_CORJE Substrate [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Pipeline of Lumavita in clinical development of anti-infectives. 2007
2 High frequency of macrolide resistance mechanisms in clinical isolates of Corynebacterium species. Microb Drug Resist. 2010 Dec;16(4):273-7.