Details of the Drug

General Information of Drug (ID: DM92LH2)

Drug Name

Pentamycin

Synonyms

FemiFect; Pentamycin; LMV-602; Pentamycin vaginal tablets (vaginitis); Pentamycin, Necura; Pentamycin, Shogoo; Pruri-Ex; SPK-0602; N-Pent, Necura; N-Pent, Shogoo; Pentamycin vaginal tablets (vaginitis), Lumavita

Indication

Disease Entry	ICD 11	Status	REF
Vulvovaginitis	GA02.0	Approved	[1]
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ATC Code

G01AA11: Pentamycin

G01AA: Antibiotics

G01A: ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS

G01: GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS

G: GENITO URINARY SYSTEM AND SEX HORMONES

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

Chemical Identifiers

Formula: C35H58O12
Canonical SMILES: CCCCCC(C1C(CC(CC(CC(CC(CC(C(C(C(=CC=CC=CC=CC=CC(C(OC1=O)C)O)C)O)O)O)O)O)O)O)O)O
InChI: 1S/C35H58O12/c1-4-5-11-16-29(41)32-30(42)20-26(38)18-24(36)17-25(37)19-27(39)21-31(43)34(45)33(44)22(2)14-12-9-7-6-8-10-13-15-28(40)23(3)47-35(32)46/h6-10,12-15,23-34,36-45H,4-5,11,16-21H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,22-14+/t23-,24+,25-,26+,27-,28+,29-,30+,31-,32-,33-,34-/m1/s1
InChIKey: AGJUUQSLGVCRQA-SWOUQTJZSA-N

Cross-matching ID

PubChem CID: 5282200
CAS Number: -98-6
UNII: 1JB340D58S
DrugBank ID: DB13571
TTD ID: D0A9ZX

Molecular Interaction Atlas of This Drug

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Ribosomal 23S RNA methyltransferase Erm (erm)	DEW6V07	A0A5N1AHF6_CORAY	Substrate	[2]
Ribosomal 23S RNA methyltransferase Erm (erm)	DEA65D8	A0A381KDL2_CORJE	Substrate	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Pipeline of Lumavita in clinical development of anti-infectives. 2007
2	High frequency of macrolide resistance mechanisms in clinical isolates of Corynebacterium species. Microb Drug Resist. 2010 Dec;16(4):273-7.