Details of the Drug

General Information of Drug (ID: DM95Y82)

Drug Name
AZ960
Synonyms AZ 960; AZ-960
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 354.4
Logarithm of the Partition Coefficient (xlogp) 4.4
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C18H16F2N6
IUPAC Name
5-fluoro-2-[[(1S)-1-(4-fluorophenyl)ethyl]amino]-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridine-3-carbonitrile
Canonical SMILES
CC1=CC(=NN1)NC2=C(C=C(C(=N2)N[C@@H](C)C3=CC=C(C=C3)F)C#N)F
InChI
InChI=1S/C18H16F2N6/c1-10-7-16(26-25-10)23-18-15(20)8-13(9-21)17(24-18)22-11(2)12-3-5-14(19)6-4-12/h3-8,11H,1-2H3,(H3,22,23,24,25,26)/t11-/m0/s1
InChIKey
SUNXHXDJOIXABJ-NSHDSACASA-N
Cross-matching ID
PubChem CID
25099184
CAS Number
905586-69-8
TTD ID
D0OP3D
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Janus kinase 2 (JAK-2) TTRMX3V JAK2_HUMAN Inhibitor [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 158 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC2 0.488 5.2899 -0.4653 32.9158
DEL GDSC2 -4.2924 0.5052 -4.422 70.6455
L-1236 GDSC2 -4.255 -1.198 -4.267 73.7882
NK-92MI GDSC2 -3.0731 -1.3771 -3.0734 64.1007
SR GDSC2 -2.6247 0.1909 -2.6492 59.2515
JVM-3 GDSC2 -2.4548 1.5982 -2.6091 56.9417
A4/Fukuda GDSC2 -2.3872 -0.3729 -2.3908 57.2217
NB4 GDSC2 -2.2604 -0.1805 -2.2656 55.9535
CRO-AP2 GDSC2 -2.1448 -0.3923 -2.1464 54.8388
AMO1 GDSC2 -2.0255 0.5373 -2.0491 53.5595
BE-13 GDSC2 -1.9547 1.5727 -2.0705 52.697
SUP-M2 GDSC2 -1.9153 -0.9546 -1.9153 52.5564
IM-9 GDSC2 -1.8373 -0.2236 -1.8386 51.769
MOLM-13 GDSC2 -1.7434 0.3021 -1.7514 50.8232
BC-3 GDSC2 -1.7071 -0.3768 -1.7074 50.4661
BC-1 GDSC2 -1.6826 0.2725 -1.689 50.2191
ATN-1 GDSC2 -1.6769 -0.0265 -1.6788 50.163
OCI-Ly19 GDSC2 -1.6645 -0.0491 -1.6662 50.0394
697 GDSC2 -1.617 3.0678 -2.0008 49.6395
SU-DHL-1 GDSC2 -1.6154 1.7373 -1.731 49.5804
OCI-M1 GDSC2 -1.5801 0.3577 -1.5869 49.1983
MV4-11 GDSC2 -1.552 0.0123 -1.5535 48.9122
JVM-2 GDSC2 -1.4732 1.6792 -1.5713 48.2334
SU-DHL-5 GDSC2 -1.3563 -0.3449 -1.3564 46.9469
CTV-1 GDSC2 -1.354 0.1851 -1.3557 46.9281
SUP-B8 GDSC2 -1.3082 0.5964 -1.3165 46.4868
MOLM-16 GDSC2 -1.3068 1.1441 -1.3414 46.5314
CCRF-CEM GDSC2 -1.3 0.6596 -1.3099 46.409
OCI-Ly7 GDSC2 -1.288 0.1078 -1.2889 46.2646
SU-DHL-6 GDSC2 -1.1985 0.2413 -1.1998 45.3677
KY821 GDSC2 -1.1681 2.3504 -1.3513 45.4856
SIG-M5 GDSC2 -1.1017 -0.4941 -1.1017 44.3914
EoL-1 GDSC2 -1.0928 0.9241 -1.1077 44.3553
L-540 GDSC2 -1.0923 2.2195 -1.2454 44.7093
HAL-01 GDSC2 -1.0662 1.5834 -1.128 44.2311
PL-21 GDSC2 -1.0498 1.3241 -1.087 43.9979
P32/ISH GDSC2 -0.9433 -0.0097 -0.9433 42.8019
KOPN-8 GDSC2 -0.9223 2.3542 -1.0862 43.1166
ML-2 GDSC2 -0.9214 2.7602 -1.1685 43.324
BONNA-12 GDSC2 -0.9109 2.3396 -1.0712 42.9977
A3/Kawakami GDSC2 -0.898 1.9148 -0.9895 42.671
Karpas-620 GDSC2 -0.8905 3.8242 -1.4216 43.6745
KMS-11 GDSC2 -0.8805 2.5754 -1.0842 42.8272
Kasumi-1 GDSC2 -0.8472 1.9002 -0.9333 42.1564
SU-DHL-16 GDSC2 -0.8273 -0.0507 -0.8273 41.6375
RCH-ACV GDSC2 -0.8201 1.4347 -0.8557 41.7107
QIMR-WIL GDSC2 -0.8095 3.7254 -1.3031 42.8918
GDM-1 GDSC2 -0.7945 7.4549 -2.7157 44.9675
RPMI-8866 GDSC2 -0.7934 2.8531 -1.0505 42.1539
RL GDSC2 -0.7694 2.0842 -0.8762 41.4628
OCI-AML-2 GDSC2 -0.7669 0.3434 -0.7673 41.0338
KMS-12-BM GDSC2 -0.7537 2.2192 -0.8806 41.3771
DoHH2 GDSC2 -0.7527 -0.0284 -0.7527 40.8896
TALL-1 [Human adult T-ALL] GDSC2 -0.7398 4.0697 -1.3354 42.5177
MOLT-16 GDSC2 -0.7296 1.677 -0.7825 40.8764
BALL-1 GDSC2 -0.7106 0.0851 -0.7106 40.4665
NU-DUL-1 GDSC2 -0.7029 4.025 -1.2808 42.1592
OCI-AML-3 GDSC2 -0.7021 3.1757 -1.0305 41.5047
MC116 GDSC2 -0.7 0.3602 -0.7002 40.3614
BL-41 GDSC2 -0.6768 -0.0524 -0.6768 40.1276
SUP-HD1 GDSC2 -0.6582 5.0807 -1.6029 42.5822
Namalwa GDSC2 -0.6484 4.4456 -1.3626 42.0112
JURL-MK1 GDSC2 -0.6338 2.7777 -0.8595 40.5483
ST486 GDSC2 -0.6335 2.0679 -0.7283 40.085
ALL-PO GDSC2 -0.6136 2.6785 -0.816 40.2766
HEL GDSC2 -0.5899 1.5621 -0.6253 39.4148
SCC-3 GDSC2 -0.5603 0.4351 -0.5605 38.9594
L-363 GDSC2 -0.5298 7.1037 -2.2905 43.058
KE-37 GDSC2 -0.521 0.7319 -0.5223 38.5704
SU-DHL-4 GDSC2 -0.5141 1.6522 -0.5536 38.675
MY-M12 GDSC2 -0.5112 3.1197 -0.8078 39.6199
Loucy GDSC2 -0.4758 1.8107 -0.5286 38.3512
SK-MM-2 GDSC2 -0.4283 2.2311 -0.5329 38.0989
Ku812 GDSC2 -0.4193 1.6785 -0.4565 37.7176
BV-173 GDSC2 -0.3952 7.2343 -2.2083 42.2397
Farage GDSC2 -0.3512 3.2351 -0.6633 38.1574
SKM-1 GDSC2 -0.3371 2.2724 -0.4415 37.1954
RPMI-6666 GDSC2 -0.3101 5.1166 -1.244 39.7361
LAMA-84 GDSC2 -0.3076 2.8786 -0.5275 37.3845
VAL GDSC2 -0.2904 3.1669 -0.5791 37.4889
JSC-1 GDSC2 -0.2855 2.7226 -0.469 37.0205
KM-H2 GDSC2 -0.2844 3.7226 -0.7301 38.0108
EM-2 GDSC2 -0.2462 2.3718 -0.3599 36.3353
H9 GDSC2 -0.2414 16.2593 -6.3125 45.4535
RPMI-8226 GDSC2 -0.1794 2.983 -0.4123 36.1908
P12-Ichikawa GDSC2 -0.1753 4.715 -0.9488 38.1221
GA-10 GDSC2 -0.1119 2.5302 -0.2429 35.0815
Daudi GDSC2 -0.1047 2.3493 -0.204 34.8635
OPM-2 GDSC2 -0.0918 1.8379 -0.1271 34.4314
WSU-NHL GDSC2 -0.0497 2.1441 -0.1157 34.1574
U266B1 GDSC2 -0.0394 3.5343 -0.4065 35.3982
Jurkat GDSC2 0.0234 6.8698 -1.6188 38.9344
Ramos.2G6.4C10 GDSC2 0.072 3.2094 -0.1947 33.8849
U-698-M GDSC2 0.0788 10.0484 -3.0175 41.3554
CTB-1 GDSC2 0.1116 4.4424 -0.5408 35.1267
DND-41 GDSC2 0.1235 5.7604 -1.0417 36.8227
HDLM-2 GDSC2 0.2664 4.6829 -0.4628 34.0134
MEG-01 GDSC2 0.3347 5.3826 -0.6646 34.4523
MOLP-8 GDSC2 0.3555 5.6525 -0.7538 34.677
KG-1 GDSC2 0.4752 3.209 0.2454 29.7326
NALM-6 GDSC2 0.4892 8.1448 -1.7233 37.0157
KCL-22 GDSC2 0.5825 2.7991 0.4571 28.1316
Jiyoye GDSC2 0.6918 5.0574 -0.1561 30.6072
JeKo-1 GDSC2 0.873 7.104 -0.8614 32.6459
HL-60 GDSC2 0.9006 7.0232 -0.7967 32.2857
CML-T1 GDSC2 0.9253 5.2879 -0.0056 28.8281
CESS GDSC2 0.9786 4.1156 0.5111 25.9836
TK [Human B-cell lymphoma] GDSC2 1.0723 5.6278 0.0019 28.1345
ALL-SIL GDSC2 1.1205 8.357 -1.2033 32.7773
MOLT-13 GDSC2 1.2254 5.0326 0.4148 25.3929
ARH-77 GDSC2 1.2342 5.4632 0.2402 26.2548
EJM GDSC2 1.2452 4.6323 0.5997 24.323
HC-1 GDSC2 1.2783 9.3181 -1.5126 33.13
TUR GDSC2 1.2896 5.7215 0.1838 26.3013
DG-75 GDSC2 1.2934 10.1208 -1.8873 34.1586
P30/OHK GDSC2 1.2942 4.4738 0.7146 23.4858
Karpas-45 GDSC2 1.2979 4.2862 0.7911 23.05
SUP-T1 GDSC2 1.3274 5.292 0.4105 24.9769
OCI-AML-5 GDSC2 1.3319 4.0235 0.9249 22.1628
MLMA GDSC2 1.3823 8.8885 -1.2065 31.7325
MHH-CALL-2 GDSC2 1.4422 5.5542 0.4137 24.4756
Reh GDSC2 1.4845 4.9288 0.7289 22.5948
MHH-CALL-4 GDSC2 1.4892 10.455 -1.8674 33.3714
NOMO-1 GDSC2 1.5785 6.9159 -0.0756 26.3687
RS4;11 GDSC2 1.8355 7.6583 -0.1824 25.8606
Karpas-1106P GDSC2 1.8656 8.4246 -0.5257 27.27
LP-1 GDSC2 1.8794 6.0747 0.6145 21.6355
Hs 445 GDSC2 1.9559 5.7835 0.8258 20.1572
VL51 GDSC2 2.0337 7.2866 0.1851 23.3249
WIL2 NS GDSC2 2.0456 7.0801 0.2962 22.7094
DB GDSC2 2.0884 8.2947 -0.2548 25.2476
NCI-H929 GDSC2 2.2514 4.7354 1.6022 14.4573
Karpas-422 GDSC2 2.3306 3.6874 2.1221 11.0823
CA46 GDSC2 2.6277 13.0365 -2.1253 30.2798
THP-1 GDSC2 2.6778 8.4327 0.2117 20.9106
JJN-3 GDSC2 2.7068 6.482 1.2039 15.2382
PF-382 GDSC2 2.7508 6.9112 1.0316 16.1191
K-562 GDSC2 2.9579 12.2542 -1.4511 27.118
HT GDSC2 3.0336 13.8292 -2.1739 29.2036
Karpas-231 GDSC2 3.0554 4.9943 2.2545 7.5753
LC4-1 GDSC2 3.1719 9.4124 0.1508 19.6326
EB2 GDSC2 3.247 9.178 0.3312 18.4692
SU-DHL-10 GDSC2 3.2852 4.3455 2.7792 3.5446
SU-DHL-8 GDSC2 3.795 6.5592 2.0786 6.5958
Raji GDSC2 3.8038 18.4417 -3.8402 31.3083
GR-ST GDSC2 3.9611 9.6118 0.6925 14.4655
HH [Human lymphoma] GDSC2 4.1323 6.4974 2.3482 4.1684
SUP-B15 GDSC2 4.3275 8.6925 1.4216 9.325
RC-K8 GDSC2 4.3784 10.7055 0.4693 14.5904
ROS-50 GDSC2 4.3789 10.9023 0.3725 15.0989
KMOE-2 GDSC2 4.5444 10.8173 0.5379 13.8121
ME1 GDSC2 4.6135 12.5376 -0.2587 17.62
MHH-PREB-1 GDSC2 4.627 8.1902 1.8706 5.9998
MN-60 GDSC2 4.8546 11.7526 0.3057 14.2775
MM1.S GDSC2 4.8719 7.7682 2.2191 3.555
MOLT-4 GDSC2 5.1456 6.6939 2.8075 0.5125
Granta-519 GDSC2 5.3149 10.7351 1.1157 8.9327
L-428 GDSC2 5.3785 14.249 -0.5369 17.051
⏷ Show the Full List of 158 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-220 GDSC2 0.8251 5.7253 -0.2956 30.6054
FLO-1 GDSC2 0.9653 4.8469 0.2177 27.5567
TE-12 GDSC2 2.0406 8.1343 -0.2207 25.2663
HCE-4 GDSC2 2.5167 6.1098 1.2109 15.8468
OACM5.1 C GDSC2 2.7399 7.7304 0.6156 18.5424
ESO-26 GDSC2 3.8202 7.5139 1.6253 9.3447
OACP4 C GDSC2 3.8947 7.2077 1.8333 7.8716
KYSE-50 GDSC2 4.1443 9.9275 0.6769 14.0681
ESO-51 GDSC2 4.9943 7.8295 2.2621 3.1301
SK-GT-4 GDSC2 5.317 15.9031 -1.3933 20.6519
KYAE-1 GDSC2 5.9318 7.5335 2.8066 0.2011
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 2.899 9.2712 -0.0122 21.3082
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MHH-NB-11 GDSC2 -1.3712 1.3975 -1.4306 47.2064
SJNB-10 GDSC2 -1.2957 1.3005 -1.3422 46.4461
KP-N-YS GDSC2 -0.9103 1.4338 -0.95 42.6225
SJNB-14 GDSC2 -0.6985 4.8691 -1.5678 42.7542
CHP-212 GDSC2 -0.4232 1.8226 -0.4743 37.8194
SJNB-13 GDSC2 -0.4 2.8524 -0.622 38.2881
NB69 GDSC2 -0.387 1.4515 -0.4067 37.3139
TGW GDSC2 -0.382 3.5617 -0.7882 38.7802
NB(TU)1 GDSC2 -0.1776 3.4386 -0.5297 36.6575
SK-N-MC-IXC GDSC2 -0.0848 4.0511 -0.6179 36.4796
NH-12 GDSC2 0.011 7.7292 -2.013 39.8848
IMR-5 GDSC2 0.1465 4.8744 -0.6637 35.4105
CHP-126 GDSC2 0.1917 8.2062 -2.048 39.1202
Kelly GDSC2 0.5429 4.7023 -0.1744 31.4038
SJNB-6 GDSC2 0.7025 3.0054 0.5431 27.1067
SK-N-AS GDSC2 0.7114 8.8418 -1.8306 36.3318
SJNB-5 GDSC2 0.8501 7.7495 -1.1822 33.852
SJNB-17 GDSC2 1.3027 5.7218 0.197 26.1799
CHP-134 GDSC2 1.3758 4.4819 0.7981 22.674
SiMa GDSC2 1.3853 6.3282 0.0068 26.7669
SK-N-DZ GDSC2 1.6392 5.772 0.5154 23.1255
KP-N-RT-BM-1 GDSC2 1.6946 8.0463 -0.5034 27.8291
KP-N-YN GDSC2 1.7 10.4015 -1.6463 31.9505
LA-N-6 GDSC2 2.3811 9.5041 -0.5844 25.6601
SJNB-7 GDSC2 2.6635 6.7969 1.0092 16.5433
GI-ME-N GDSC2 3.4927 8.2129 1.0173 13.911
GOTO GDSC2 3.7306 7.7727 1.4273 10.7935
SK-N-BE(2)-M17 GDSC2 5.129 13.3771 -0.2907 16.5224
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 4.4871 9.5548 1.1151 10.7423
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NY GDSC2 -1.0497 1.8862 -1.1475 44.1669
EW-12 GDSC2 -0.9024 0.2488 -0.9027 42.3932
ES8 GDSC2 -0.8654 2.4442 -1.0416 42.6071
SK-PN-DW GDSC2 0.0468 5.2912 -0.9323 36.8691
SK-ES-1 GDSC2 0.2651 2.408 0.1836 31.0849
EW-18 GDSC2 0.3697 3.9819 -0.1015 31.929
CADO-ES1 GDSC2 0.4714 8.22 -1.7758 37.2284
TC-71 GDSC2 0.6829 6.3541 -0.7161 32.969
CHSA0011 GDSC2 0.7903 4.6344 0.1156 28.8661
EW-22 GDSC2 0.8194 6.1922 -0.505 31.5138
G-292 clone A141B1 GDSC2 1.0678 3.9 0.6829 24.6631
ES5 GDSC2 1.1436 7.7834 -0.9095 31.6563
A-673 GDSC2 1.2164 4.6148 0.5763 24.5746
EW-3 GDSC2 1.228 6.9616 -0.442 29.4586
MHH-ES-1 GDSC2 1.2437 5.8405 0.0841 26.9911
CAL-78 GDSC2 1.2685 4.641 0.621 24.1069
HuO9 GDSC2 1.4242 6.3805 0.0216 26.534
CHSA0108 GDSC2 1.4319 6.4822 -0.0176 26.6905
CHSA8926 GDSC2 1.4754 4.1108 1.0472 20.8556
EW-16 GDSC2 1.7027 8.4101 -0.6717 28.4948
ES7 GDSC2 1.7536 8.338 -0.5888 27.96
MG-63 GDSC2 1.7889 8.3498 -0.5612 27.71
SaOS-2 GDSC2 1.7952 6.9407 0.1232 24.5455
HOS GDSC2 1.9068 8.4994 -0.5236 27.1065
EW-1 GDSC2 2.1359 7.3646 0.2434 22.6483
U-CH2 GDSC2 2.2241 6.9439 0.5308 20.8012
H-EMC-SS GDSC2 2.6713 6.6379 1.0948 16.0105
CAL-72 GDSC2 3.1763 11.0497 -0.6639 23.4135
U2OS GDSC2 3.2095 10.4618 -0.3422 21.895
HuO-3N1 GDSC2 3.2379 7.0344 1.3952 12.3883
ES6 GDSC2 3.3117 7.5787 1.185 13.4439
NOS-1 [Human HNSCC] GDSC2 3.4472 14.4729 -2.1495 27.9527
EW-11 GDSC2 4.3191 14.4406 -1.4298 23.2161
EW-13 GDSC2 4.5561 16.3814 -2.21 25.2449
EW-7 GDSC2 4.6811 9.7902 1.1386 10.1586
EW-24 GDSC2 5.1741 6.7842 2.7853 0.565
ES4 GDSC2 5.9719 15.9443 -0.9404 17.4446
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1187 GDSC2 -1.1472 2.0187 -1.2713 45.1688
Hs 578T GDSC2 -0.2007 2.8364 -0.4015 36.2632
DU4475 GDSC2 0.044 2.8546 -0.1394 33.7786
MFM-223 GDSC2 0.5946 5.0644 -0.2616 31.5402
CAL-51 GDSC2 0.6036 5.0477 -0.2455 31.4264
MDA-MB-361 GDSC2 1.5011 4.9545 0.7352 22.4905
BT-474 GDSC2 1.5338 12.8175 -2.9876 35.9256
HCC1569 GDSC2 1.7702 7.7221 -0.2753 26.5373
MDA-MB-453 GDSC2 2.0587 10.7863 -1.509 30.2436
Evsa-T GDSC2 2.2331 7.1052 0.4607 21.1486
CAL-120 GDSC2 2.5147 7.133 0.708 18.7881
HCC1599 GDSC2 2.6065 10.1229 -0.6917 25.347
HDQ-P1 GDSC2 2.6431 9.2146 -0.2076 23.086
MDA-MB-468 GDSC2 2.8179 8.1243 0.4887 18.9823
HCC2157 GDSC2 2.9459 5.3929 1.9585 9.79
JIMT-1 GDSC2 3.0937 6.0672 1.7548 10.5962
MDA-MB-231 GDSC2 3.1681 8.8492 0.4291 18.191
AU565 GDSC2 3.4497 9.7992 0.1891 18.5977
MDA-MB-157 GDSC2 3.5639 11.4222 -0.5284 21.6729
HCC1806 GDSC2 3.714 7.1729 1.7127 9.0827
BT-549 GDSC2 3.7248 10.6732 -0.0236 18.8659
EFM-19 GDSC2 3.7996 10.3942 0.1755 17.661
HCC1500 GDSC2 3.8448 11.7271 -0.4533 20.5407
HCC1954 GDSC2 4.1455 7.7941 1.7295 7.9
HCC2218 GDSC2 4.3423 14.1065 -1.2454 22.4703
CAL-85-1 GDSC2 4.368 9.861 0.878 12.3807
MDA-MB-330 GDSC2 4.451 13.2614 -0.7411 20.1702
MDA-MB-436 GDSC2 4.6207 11.3631 0.3257 14.7385
HCC70 GDSC2 4.9532 11.2624 0.6154 12.4318
HCC1419 GDSC2 5.0535 6.5727 2.815 0.545
T-47D GDSC2 5.1522 11.2364 0.7666 11.1783
EFM-192A GDSC2 5.3109 7.4979 2.5667 1.2699
MCF-7 GDSC2 5.402 7.462 2.6224 0.9712
HCC1428 GDSC2 5.4112 13.3496 -0.0755 14.8759
HCC38 GDSC2 5.4283 15.713 -1.2178 19.7343
MRK-nu-1 GDSC2 5.5003 7.243 2.7471 0.495
HCC1143 GDSC2 5.5763 16.1836 -1.3406 19.868
HCC1937 GDSC2 5.5996 13.038 0.2061 13.1054
YMB-1-E GDSC2 5.7288 13.5049 0.0698 13.4945
BT-20 GDSC2 5.7663 7.6365 2.7082 0.4703
COLO 824 GDSC2 5.9351 9.4471 2.0653 2.8511
UACC-893 GDSC2 5.9362 8.1243 2.5962 0.6988
OCUB-M GDSC2 5.9417 7.9449 2.6646 0.5029
CAMA-1 GDSC2 5.9426 15.473 -0.7324 16.6503
ZR-75-30 GDSC2 5.9479 7.7471 2.7379 0.326
MDA-MB-415 GDSC2 6.6832 20.7767 -2.7874 22.3407
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H4 GDSC2 -0.6107 1.815 -0.6716 39.7272
T98G GDSC2 -0.4075 1.9616 -0.4734 37.7276
Hs 683 GDSC2 -0.3204 2.4012 -0.4448 37.1161
D283 Med GDSC2 -0.1455 4.089 -0.6964 37.1039
YH-13 GDSC2 -0.0027 2.9272 -0.2067 34.3339
A-172 GDSC2 0.0918 3.6255 -0.2906 34.2042
D-336MG GDSC2 0.1171 3.48 -0.22 33.761
KS-1 [Human Krukenberg tumour] GDSC2 0.1283 5.2164 -0.8162 36.0515
D-245MG GDSC2 0.1734 4.185 -0.3833 34.1684
SF539 GDSC2 0.5719 5.8093 -0.5941 33.0237
SF126 GDSC2 0.6332 3.6062 0.3053 28.6637
Daoy GDSC2 0.7481 7.7506 -1.2837 34.6212
D-247MG GDSC2 0.7813 4.5629 0.1335 28.8199
SNB-75 GDSC2 0.8954 6.9679 -0.7766 32.2332
D-542MG GDSC2 0.9786 4.7356 0.2762 27.2014
D-502MG GDSC2 1.0628 6.5406 -0.4139 30.0491
GI-1 GDSC2 1.1114 3.9529 0.7119 24.3091
GaMG GDSC2 1.1532 4.5229 0.5455 25.0173
DK-MG GDSC2 1.2451 7.1474 -0.5116 29.6783
42-MG-BA GDSC2 1.2689 4.0182 0.859 22.8043
D-566MG GDSC2 1.2926 3.8259 0.9517 22.1894
KALS-1 GDSC2 1.3482 5.9865 0.1249 26.3462
CAS-1 GDSC2 1.378 4.4441 0.8153 22.5692
Becker GDSC2 1.4721 6.0613 0.2157 25.3749
D-263MG GDSC2 1.4834 3.9418 1.1176 20.4264
SW1088 GDSC2 1.6054 5.6543 0.5347 23.1586
M059J GDSC2 1.7422 6.8465 0.1166 24.7854
AM-38 GDSC2 1.8582 6.9738 0.1682 24.076
KINGS-1 GDSC2 1.8691 8.7463 -0.6792 27.8945
NMC-G1 GDSC2 2.0462 7.7514 -0.0288 24.3392
D-392MG GDSC2 2.153 6.8002 0.5332 21.0483
SK-MG-1 GDSC2 2.1932 4.4312 1.6768 14.2415
GB-1 GDSC2 2.2761 7.4529 0.3311 21.6829
KNS-42 GDSC2 2.3637 8.4786 -0.0929 23.5011
D-423MG GDSC2 2.636 10.8029 -1.0045 26.5018
PFSK-1 GDSC2 2.6901 9.2798 -0.1986 22.887
8-MG-BA GDSC2 2.989 9.463 -0.0303 21.1083
YKG-1 GDSC2 2.9956 15.9664 -3.2743 32.1494
DBTRG-05MG GDSC2 3.0529 8.3832 0.5638 17.8181
SF268 GDSC2 3.3986 9.7558 0.1687 18.8537
LN-18 GDSC2 3.4022 8.7008 0.6991 16.0015
Onda 10 GDSC2 3.4901 7.8323 1.2053 12.8033
SF295 GDSC2 3.4987 14.742 -2.2415 28.0851
U-118MG GDSC2 3.7894 8.7577 0.9832 13.2795
ONS-76 GDSC2 3.8903 11.1004 -0.1044 18.7938
U-251MG GDSC2 4.1839 9.1499 1.0914 11.618
Onda 11 GDSC2 4.2261 9.4381 0.9808 12.1501
LN-405 GDSC2 4.468 10.1411 0.814 12.4936
KNS-81-FD GDSC2 4.5461 12.0893 -0.0881 16.9834
U-87MG ATCC GDSC2 4.7219 15.5421 -1.6643 23.0406
LN-229 GDSC2 5.3067 10.7387 1.1086 8.9882
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC2 3.558 6.1748 2.0872 7.1553
TGBC24TKB GDSC2 4.4575 7.4422 2.1139 4.9047
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 GDSC2 -0.6883 2.3108 -0.8258 40.7767
AN3-CA GDSC2 -0.2335 4.8971 -1.0789 38.8437
EN GDSC2 1.5532 11.5554 -2.348 34.4103
MFE-280 GDSC2 1.5718 4.5988 0.9579 20.9481
KLE GDSC2 3.7059 12.6366 -1.0194 23.3132
MFE-296 GDSC2 4.2708 6.6436 2.3696 3.764
MFE-319 GDSC2 4.9025 9.4564 1.4509 7.8833
RL95-2 GDSC2 5.0534 17.0012 -2.1337 23.8174
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-140 GDSC2 -0.406 2.9782 -0.658 38.459
CAL-54 GDSC2 0.0419 3.0343 -0.1834 33.9923
A-704 GDSC2 0.1804 2.9708 -0.0174 32.4974
LB996-RCC GDSC2 0.2066 5.588 -0.8834 35.8801
Caki-1 GDSC2 0.4763 5.3313 -0.4945 33.0911
KTCTL-26A GDSC2 0.52 5.5553 -0.5411 33.0642
KTCTL-13 GDSC2 0.6796 4.6229 0.0019 29.9337
RXF 393L GDSC2 0.6979 3.9149 0.2769 28.4988
NCC010 GDSC2 0.9052 5.0687 0.0642 28.5854
LB1047-RCC GDSC2 1.34 6.0449 0.0901 26.5521
769-P GDSC2 1.3422 5.5726 0.3033 25.4711
SW156 GDSC2 1.4254 7.6753 -0.584 29.2326
BFTC-909 GDSC2 1.48 8.6496 -0.9984 30.6162
UO-31 GDSC2 1.6165 6.6575 0.0831 25.4496
NCC021 GDSC2 1.7161 5.8569 0.5536 22.6104
KTCTL-21 GDSC2 1.8705 9.8104 -1.1992 29.8604
786-O GDSC2 1.8831 5.703 0.791 20.6363
LB2241-RCC GDSC2 2.125 9.4952 -0.8113 27.4913
KTCTL-1M GDSC2 2.1786 5.2943 1.2737 16.6982
SW13 GDSC2 2.3322 7.0069 0.6012 20.025
A-498 GDSC2 2.5835 9.7774 -0.5401 24.7814
KTCTL-195 GDSC2 2.8008 11.5247 -1.2214 26.7862
HA7-RCC GDSC2 3.1778 9.561 0.0815 19.9643
TK-10 GDSC2 3.1781 6.8513 1.436 12.3184
KMRC-20 GDSC2 3.4657 7.511 1.346 12.0225
OS-RC-2 GDSC2 3.617 6.3888 2.0269 7.3771
BB65-RCC GDSC2 3.9244 18.0846 -3.5636 30.4066
ACHN GDSC2 4.0291 15.4078 -2.1423 26.3652
VMRC-RCW GDSC2 4.2282 12.916 -0.7423 20.7555
VMRC-RCZ GDSC2 4.405 7.9617 1.8309 6.6999
SN12C GDSC2 4.6562 7.6405 2.1474 4.3315
RCC10RGB GDSC2 5.0053 9.6311 1.4358 7.7597
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H716 GDSC2 -0.4489 1.8092 -0.5 38.0751
SW48 GDSC2 -0.2918 2.172 -0.3778 36.6651
HCT 116 GDSC2 0.3156 5.5493 -0.7529 34.8728
GP5d GDSC2 0.8025 4.0347 0.3493 27.6376
SW620 GDSC2 1.0517 5.8113 -0.0993 28.7014
T84 GDSC2 1.0923 3.3196 0.8893 23.4389
HCT 15 GDSC2 1.1862 7.5452 -0.7557 30.9009
HT115 GDSC2 1.4465 4.4993 0.866 21.9935
SK-CO-1 GDSC2 1.4577 5.5554 0.4289 24.3313
CL-11 GDSC2 1.5963 5.761 0.4773 23.5038
LS513 GDSC2 1.7581 6.2775 0.4003 23.2662
CaR-1 GDSC2 2.6249 6.1689 1.2827 15.0401
RKO GDSC2 2.6606 10.601 -0.8824 25.9437
HT-29 GDSC2 2.711 5.6881 1.5977 12.8196
NCI-H747 GDSC2 2.7504 9.6311 -0.3207 23.2534
SNU-C2B GDSC2 2.8569 7.6046 0.7818 17.2225
SW626 GDSC2 2.9524 9.6519 -0.156 21.8313
C2BBe1 GDSC2 3.0815 6.3251 1.6155 11.5036
COLO205 GDSC2 3.256 5.5847 2.1351 7.7071
LS411N GDSC2 3.3456 7.5938 1.2056 13.2202
SNU-61 GDSC2 3.3511 7.2851 1.3646 12.2407
SNU-C5 GDSC2 3.4016 9.0078 0.5451 16.8564
LS123 GDSC2 3.5272 5.5092 2.3943 5.3029
HCC2998 GDSC2 3.6293 7.8586 1.3044 11.8153
LS180 GDSC2 3.7048 10.4836 0.0549 18.5353
CCK-81 GDSC2 3.7215 9.7568 0.4311 16.5476
RCM-1 [Human ESC] GDSC2 3.7736 7.0054 1.8418 8.1254
LoVo GDSC2 3.8806 11.814 -0.468 20.507
SNU-1040 GDSC2 4.0318 10.8437 0.135 17.2275
SNU-175 GDSC2 4.1236 7.7421 1.7391 7.8936
HT-55 GDSC2 4.1358 7.5014 1.8656 7.0933
SW948 GDSC2 4.1873 7.3901 1.9561 6.424
CW-2 GDSC2 4.2188 10.2408 0.5785 14.4129
SNU-81 GDSC2 4.2705 8.7865 1.3343 9.9792
MDST8 GDSC2 4.2904 11.1081 0.2035 16.1964
COLO 320HSR GDSC2 4.307 9.8945 0.8161 12.8794
SNU-283 GDSC2 4.4345 12.3863 -0.3197 18.3554
SW1116 GDSC2 4.6177 10.6432 0.677 12.885
SNU-C1 GDSC2 4.7817 6.7158 2.6317 1.5399
KM12 GDSC2 5.0026 6.9273 2.6527 1.2039
SW1463 GDSC2 5.0555 7.7661 2.3241 2.7148
LS1034 GDSC2 5.1978 6.9751 2.7224 0.7614
SW1417 GDSC2 5.2103 15.5345 -1.291 20.5147
SNU-407 GDSC2 5.3657 15.3246 -1.073 19.312
SW837 GDSC2 5.3869 7.7996 2.4801 1.5639
NCI-H508 GDSC2 5.5146 17.8579 -2.2094 23.0117
COLO 678 GDSC2 5.6053 9.1604 2.0143 3.5345
DiFi GDSC2 7.2713 9.431 2.6318 0.1758
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 4.5157 7.3949 2.1736 4.4416
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HLE GDSC2 0.2227 5.127 -0.6807 35.0792
SNU-398 GDSC2 0.5546 5.3306 -0.4118 32.3728
HuH-1 GDSC2 0.8824 4.4868 0.2705 27.6691
SNU-423 GDSC2 2.4772 9.534 -0.5134 25.0258
SNU-449 GDSC2 2.5356 8.2828 0.1592 21.661
Hep 3B2.1-7 GDSC2 2.7332 8.5535 0.2006 20.7829
JHH-7 GDSC2 3.2297 13.2703 -1.7294 27.2482
JHH-6 GDSC2 3.4254 7.6749 1.231 12.8348
SNU-387 GDSC2 3.5511 11.063 -0.3594 20.9535
JHH-4 GDSC2 3.841 11.1819 -0.1843 19.3124
Hep-G2/C3A GDSC2 4.0578 7.5431 1.7888 7.7471
JHH-1 GDSC2 4.1612 13.3792 -1.0255 22.0917
Huh-7 GDSC2 4.1784 8.5343 1.3905 9.8684
JHH-2 GDSC2 4.4044 6.6558 2.4475 3.0681
SK-HEP-1 GDSC2 4.5449 12.4854 -0.2848 17.9133
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 166 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LK-2 GDSC2 -0.8526 2.1745 -0.9797 42.3393
IST-SL1 GDSC2 -0.8306 3.4091 -1.234 42.8712
NCI-H510A GDSC2 -0.778 0.578 -0.7796 41.1507
NCI-H526 GDSC2 -0.6887 2.8736 -0.9412 41.155
NCI-H82 GDSC2 -0.6285 2.5257 -0.8009 40.3173
NCI-H2171 GDSC2 -0.6029 0.672 -0.6042 39.3922
NCI-H524 GDSC2 -0.5633 1.7647 -0.6161 39.2226
NCI-H3122 GDSC2 -0.5032 4.4018 -1.1904 40.7104
NCI-H2122 GDSC2 -0.3922 2.4546 -0.5318 37.8871
NCI-H292 GDSC2 -0.3625 4.2616 -0.9898 39.313
NCI-H1963 GDSC2 -0.3329 1.7635 -0.3735 36.8695
COR-L321 GDSC2 -0.3199 2.1008 -0.3979 36.9092
NCI-H1876 GDSC2 -0.1894 16.5842 -6.4228 45.3593
NCI-H460 GDSC2 -0.1274 3.2901 -0.4338 35.9927
SBC-3 GDSC2 0.0066 4.5296 -0.6853 36.2306
NCI-H2081 GDSC2 0.0767 3.5875 -0.2956 34.3051
Lu-134-A GDSC2 0.1942 6.0637 -1.0948 36.6305
EMC-BAC-1 GDSC2 0.2071 5.2391 -0.7416 35.3809
NCI-H1581 GDSC2 0.3031 4.8086 -0.4713 33.8609
LC-2/ad GDSC2 0.3732 3.4514 0.0676 31.1139
NCI-H1048 GDSC2 0.3942 2.4568 0.3146 29.7826
NCI-H1437 GDSC2 0.4377 6.2264 -0.9121 34.8342
NCI-H211 GDSC2 0.5102 3.2553 0.2714 29.4305
VMRC-LCD GDSC2 0.5696 7.2289 -1.2228 35.2317
NCI-H2795 GDSC2 0.5775 4.3732 -0.0141 30.4987
DMS 273 GDSC2 0.591 4.2486 0.0455 30.1506
EMC-BAC-2 GDSC2 0.5929 6.5161 -0.8796 33.9843
NCI-H647 GDSC2 0.6734 5.6959 -0.4404 31.9252
RERF-LC-MS GDSC2 0.6785 4.0262 0.2181 28.886
NCI-H446 GDSC2 0.717 7.3495 -1.1299 34.2679
NCI-H838 GDSC2 0.8449 4.89 0.073 28.8198
SBC-5 GDSC2 0.9179 6.297 -0.4509 30.8454
NCI-H2804 GDSC2 0.9987 7.7301 -1.0266 32.6872
NCI-H2085 GDSC2 1.0265 4.8403 0.285 26.9414
NCI-H1436 GDSC2 1.046 6.0273 -0.2004 29.1887
COR-L303 GDSC2 1.0674 5.6628 -0.0184 28.2521
NCI-H1792 GDSC2 1.0764 3.9501 0.675 24.6663
A-427 GDSC2 1.2138 6.7584 -0.3622 29.1769
NCI-H1770 GDSC2 1.2378 6.4387 -0.1916 28.3176
NCI-H358 GDSC2 1.2484 8.5988 -1.1953 32.2286
NCI-H209 GDSC2 1.256 8.4356 -1.11 31.9064
NCI-H2170 GDSC2 1.2859 3.3085 1.1036 21.3896
COR-L311 GDSC2 1.3438 4.7013 0.676 23.4822
NCI-H2227 GDSC2 1.3635 5.6491 0.2913 25.4428
LCLC-103H GDSC2 1.3703 7.3405 -0.4791 29.0218
LB647-SCLC GDSC2 1.3886 8.7158 -1.1173 31.4008
PC-14 GDSC2 1.4203 6.3119 0.0492 26.4159
NCI-H226 GDSC2 1.4443 10.9947 -2.1731 34.3578
SBC-1 GDSC2 1.4771 5.4704 0.4864 23.9449
A-549 GDSC2 1.5015 6.6008 -0.0037 26.3377
SHP-77 GDSC2 1.506 5.2378 0.6182 23.1134
NCI-H720 GDSC2 1.5208 5.5143 0.5116 23.6291
NCI-H1155 GDSC2 1.5237 4.8675 0.7956 22.0599
LXF 289 GDSC2 1.532 4.2334 1.0614 20.5321
NCI-H2228 GDSC2 1.5326 7.9697 -0.6212 28.9544
EPLC-272H GDSC2 1.536 6.0658 0.2778 24.7961
Ms-1 GDSC2 1.6027 4.4026 1.0701 20.1827
LCLC-97TM1 GDSC2 1.6611 5.3138 0.7436 21.7847
NCI-H522 GDSC2 1.6934 9.6365 -1.2775 30.783
HCC33 GDSC2 1.7789 9.1088 -0.9402 29.2547
CAL-12T GDSC2 1.7796 13.4565 -3.0818 35.32
NCI-H810 GDSC2 1.7827 7.9334 -0.3653 26.8912
NCI-H2731 GDSC2 1.7838 5.311 0.8698 20.581
COR-L32 GDSC2 1.8037 7.5757 -0.1729 25.9387
IST-SL2 GDSC2 1.805 7.6206 -0.1933 26.0282
NCI-H1755 GDSC2 1.8272 6.4429 0.3903 23.0483
HCC15 GDSC2 1.8329 5.5984 0.789 20.8442
HCC78 GDSC2 1.8626 12.0985 -2.3349 33.3152
NCI-H2869 GDSC2 1.9308 5.5829 0.8939 19.8655
NCI-H596 GDSC2 1.9795 5.4166 1.0189 18.9566
NCI-H1105 GDSC2 2.0241 8.6245 -0.4758 26.4665
NCI-H1651 GDSC2 2.0814 12.5915 -2.3833 32.717
NCI-H2110 GDSC2 2.1415 11.5626 -1.8192 30.9373
Lu-99A GDSC2 2.1534 6.1937 0.8251 19.4157
NCI-H1915 GDSC2 2.1548 8.3746 -0.2326 24.9036
NCI-H1299 GDSC2 2.1606 11.3988 -1.7209 30.5711
DMS 114 GDSC2 2.1975 11.0655 -1.5227 29.8122
NCI-H2810 GDSC2 2.2525 4.077 1.8877 12.7614
HOP-62 GDSC2 2.3341 7.4525 0.385 21.1908
HARA [Human squamous cell lung carcinoma] GDSC2 2.3433 8.0516 0.0991 22.6331
SK-LU-1 GDSC2 2.3474 9.6086 -0.6664 26.121
NCI-H2803 GDSC2 2.4134 6.5877 0.8814 18.1518
NCI-H290 GDSC2 2.4365 9.7947 -0.6791 25.8675
HCC366 GDSC2 2.4398 9.2845 -0.4231 24.7581
NCI-H1355 GDSC2 2.4537 12.0313 -1.7759 29.777
NCI-H2030 GDSC2 2.4663 16.5764 -4.0312 35.1347
NCI-H2818 GDSC2 2.4938 6.5019 0.9982 17.1894
SW1271 GDSC2 2.4952 7.1159 0.6985 18.9092
NCI-H2722 GDSC2 2.784 8.7522 0.1464 20.8916
NCI-H1869 GDSC2 2.7915 7.7865 0.6336 18.2722
UMC-11 GDSC2 2.8432 11.8684 -1.3565 27.1402
SK-MES-1 GDSC2 2.9991 6.9609 1.2269 14.148
Lu-135 GDSC2 3.0059 7.1978 1.1147 14.8003
NCI-H841 GDSC2 3.0353 7.6754 0.9019 15.9607
BEN GDSC2 3.0445 14.2243 -2.3621 29.7121
LOU-NH91 GDSC2 3.0659 10.9983 -0.7317 24.0384
NCI-H23 GDSC2 3.0707 12.0217 -1.2391 26.0133
NCI-H2023 GDSC2 3.1124 7.2299 1.1907 14.0124
Lu-65 GDSC2 3.2136 9.8142 -0.0149 20.3316
HOP-92 GDSC2 3.2511 8.2178 0.8147 15.7983
NCI-H2291 GDSC2 3.2875 9.0235 0.4424 17.7548
NCI-H146 GDSC2 3.3172 7.6713 1.1433 13.6774
NCI-H748 GDSC2 3.3234 7.9867 0.9907 14.5622
NCI-H2087 GDSC2 3.4717 8.4978 0.8577 14.8982
Calu-3 GDSC2 3.491 10.3749 -0.0647 19.7413
RERF-LC-KJ GDSC2 3.5244 9.7661 0.267 17.9775
Lu-139 GDSC2 3.5596 9.5042 0.4265 17.0346
NCI-H250 GDSC2 3.5758 8.3962 0.9931 13.8153
CPC-N GDSC2 3.5775 9.8073 0.2897 17.7048
SW1573 GDSC2 3.6882 9.2627 0.651 15.4457
NCI-H1666 GDSC2 3.7072 10.5836 0.007 18.7655
NCI-H2373 GDSC2 3.7236 11.4385 -0.4067 20.6725
NCI-H322M GDSC2 3.7566 8.6307 1.0205 13.1521
NCI-H1944 GDSC2 3.7707 9.0816 0.807 14.3412
NCI-H1694 GDSC2 3.8989 7.6754 1.6053 9.265
NCI-H1975 GDSC2 3.9041 8.9825 0.9609 13.099
NCI-H1734 GDSC2 3.925 8.5833 1.1754 11.7905
NCI-H1563 GDSC2 3.9503 11.8838 -0.4473 20.2216
EKVX GDSC2 3.9555 9.3871 0.7998 13.8805
HCC44 GDSC2 3.9668 12.6991 -0.8407 21.8681
NCI-H1836 GDSC2 3.9888 8.0023 1.5116 9.609
NCI-H740 GDSC2 3.9895 8.0122 1.5073 9.6334
NCI-H2461 GDSC2 3.993 13.9108 -1.4242 24.0538
NCI-H2591 GDSC2 4.0244 11.5178 -0.2063 18.9109
NCI-H2369 GDSC2 4.1333 8.0024 1.6186 8.6037
Calu-6 GDSC2 4.1357 13.4528 -1.0823 22.3836
NCI-H1092 GDSC2 4.1768 10.1692 0.582 14.5025
NCI-H1781 GDSC2 4.1885 11.7126 -0.1749 18.3217
NCI-H1693 GDSC2 4.2025 10.0935 0.6391 14.1253
NCI-H520 GDSC2 4.2149 13.4215 -1.0043 21.8655
IA-LM GDSC2 4.2212 9.9501 0.7241 13.609
NCI-H2029 GDSC2 4.2375 11.7 -0.1307 17.9822
NCI-H2444 GDSC2 4.244 10.5359 0.4517 15.0278
NCI-H2141 GDSC2 4.3076 9.7219 0.9016 12.397
NCI-H345 GDSC2 4.3437 6.1087 2.6598 1.9918
RERF-LC-Sq1 GDSC2 4.3577 8.3848 1.5931 8.231
COLO 668 GDSC2 4.4267 8.1305 1.7644 7.0505
NCI-H2135 GDSC2 4.4842 7.9304 1.8995 6.1213
NCI-H661 GDSC2 4.4977 9.2493 1.2718 9.8099
NCI-H1993 GDSC2 4.5306 10.9058 0.4841 14.1321
EBC-1 GDSC2 4.5357 10.6416 0.6178 13.4042
NCI-H650 GDSC2 4.6169 15.2153 -1.583 23.0135
Lu-165 GDSC2 4.6647 8.1393 1.9193 5.6388
COR-L23 GDSC2 4.7077 13.7671 -0.7955 19.7511
DMS 79 GDSC2 4.7136 11.5185 0.3177 14.5533
NCI-H1568 GDSC2 4.7701 11.6858 0.2769 14.6258
DMS 53 GDSC2 4.7846 7.6618 2.2159 3.7179
NCI-H1623 GDSC2 4.8304 13.6561 -0.6482 18.8249
COR-L105 GDSC2 4.8413 15.8319 -1.7163 22.9318
ChaGo-K-1 GDSC2 4.942 9.5302 1.4419 7.8536
NCI-H1650 GDSC2 4.9661 15.1254 -1.2718 21.0184
NCI-H2172 GDSC2 4.9747 11.3773 0.5747 12.5989
NCI-H2595 GDSC2 5.0331 11.1498 0.726 11.6589
NCI-H3255 GDSC2 5.0364 19.0163 -3.1463 26.7827
HCC827 GDSC2 5.2975 10.5718 1.1816 8.6029
NCI-H2196 GDSC2 5.3143 7.0964 2.7257 0.6696
NCI-H196 GDSC2 5.4013 12.4677 0.3445 12.8412
NCI-H441 GDSC2 5.419 15.052 -0.9005 18.4971
ABC-1 GDSC2 5.4758 10.4743 1.3417 7.3738
NCI-H1793 GDSC2 5.4911 19.4154 -2.9963 25.3803
NCI-H727 GDSC2 5.7477 15.2566 -0.7645 17.2038
NCI-H1435 GDSC2 5.8301 7.4159 2.8106 0.2208
NCI-H513 GDSC2 6.0157 8.0921 2.64 0.533
NCI-H2405 GDSC2 6.172 13.0672 0.5703 10.1429
LC-1/sq GDSC2 6.7561 8.8501 2.6484 0.2569
KNS-62 GDSC2 7.0437 17.2659 -0.8457 14.9251
⏷ Show the Full List of 166 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 3.2716 10.6123 -0.3653 21.8113
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-11 GDSC2 -0.2423 1.448 -0.2571 35.8405
TE-8 GDSC2 0.591 4.4948 -0.0445 30.5759
TE-10 GDSC2 0.7866 4.6795 0.0942 28.9876
OE19 GDSC2 1.2453 7.3582 -0.6099 30.0795
OE33 GDSC2 1.5124 4.8233 0.8024 22.0693
TE-15 GDSC2 1.7514 5.8682 0.5836 22.3066
EC-GI-10 GDSC2 1.9386 7.1014 0.184 23.6886
KYSE-270 GDSC2 2.5864 7.8193 0.4342 20.05
KYSE-180 GDSC2 2.6151 6.8452 0.9414 17.1046
TE-9 GDSC2 2.7689 8.7543 0.1321 21.0137
KYSE-520 GDSC2 2.7926 8.6798 0.19 20.6409
TE-1 GDSC2 2.7929 7.3418 0.8557 17.0077
OE21 GDSC2 2.9705 9.0391 0.1654 20.1905
KYSE-140 GDSC2 3.2872 13.1245 -1.6084 26.6757
TE-4 GDSC2 3.4988 7.155 1.5507 10.6728
KYSE-410 GDSC2 3.7843 7.5263 1.5916 9.6455
KYSE-510 GDSC2 4.3367 9.0585 1.2491 10.3221
TE-5 GDSC2 4.5312 9.0001 1.4166 8.885
TE-6 GDSC2 4.5335 10.6533 0.6104 13.4494
COLO 680N GDSC2 5.1655 17.4147 -2.2532 23.9362
KYSE-70 GDSC2 5.3051 13.5326 -0.2399 15.8831
KYSE-450 GDSC2 6.9037 20.4351 -2.4647 20.9464
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A2780 GDSC2 0.6977 6.49 -0.7611 33.069
Caov-3 GDSC2 0.9747 7.2386 -0.8218 32.0541
IGROV-1 GDSC2 1.1574 6.4261 -0.2666 28.9993
JHOS-2 GDSC2 1.1709 6.6847 -0.3711 29.3985
DOV13 GDSC2 1.5808 3.162 1.4629 18.088
OVTOKO GDSC2 1.6549 7.8271 -0.4357 27.694
JHOS-4 GDSC2 1.8137 11.4291 -2.0483 32.7179
TOV-112D GDSC2 3.0075 8.2542 0.5891 17.8217
TOV-21G GDSC2 3.0741 9.1697 0.189 19.7422
OAW42 GDSC2 3.647 9.9932 0.2532 17.6942
OVCAR-8 GDSC2 3.7693 7.1436 1.7699 8.5833
EFO-27 GDSC2 3.9316 11.8478 -0.4442 20.2595
OV56 GDSC2 4.4008 9.3414 1.1571 10.7049
OVISE GDSC2 4.4364 13.0585 -0.6516 19.8269
OVCAR-5 GDSC2 4.4648 11.586 0.0994 16.2729
OV-90 GDSC2 4.8032 9.1333 1.5387 7.5811
OVCAR-3 GDSC2 4.8661 12.8221 -0.2108 16.7759
TYK-nu GDSC2 4.8779 11.8802 0.2601 14.4544
OVK18 GDSC2 4.8923 11.6157 0.3997 13.7054
ES-2 GDSC2 4.9038 11.4342 0.4966 13.1736
EFO-21 GDSC2 4.9968 14.881 -1.128 20.3909
OVCAR-4 GDSC2 5.7224 15.4291 -0.8664 17.681
Kuramochi GDSC2 5.73 16.3373 -1.3043 19.3914
OAW28 GDSC2 5.8138 13.4006 0.1775 12.7961
SK-OV-3 GDSC2 6.3101 17.792 -1.5994 19.2479
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-4 GDSC2 1.7451 5.1077 0.9207 20.4472
Capan-2 GDSC2 2.2163 7.5942 0.2065 22.5448
DAN-G GDSC2 2.2273 6.2121 0.8872 18.7872
CFPAC-1 GDSC2 2.2328 6.0963 0.9479 18.4159
PSN1 GDSC2 2.6886 5.6837 1.5791 13.011
Panc 02.03 GDSC2 2.7933 6.8591 1.0955 15.5999
MIA PaCa-2 GDSC2 2.9056 10.0486 -0.3944 23.0835
PL4 GDSC2 2.9164 13.3338 -2.0258 29.1096
PaTu 8902 GDSC2 3.156 9.2996 0.1937 19.463
QGP-1 GDSC2 3.3343 10.2896 -0.1516 20.6264
KP-3 GDSC2 3.6967 12.8106 -1.1138 23.7074
HuP-T4 GDSC2 3.7845 8.4558 1.1296 12.4352
Panc 08.13 GDSC2 3.847 9.7657 0.5264 15.6862
Panc 10.05 GDSC2 3.959 10.844 0.0778 17.7123
HuP-T3 GDSC2 3.9827 7.5727 1.7189 8.3581
MZ-PC-1 GDSC2 4.046 9.7044 0.7122 14.1307
PaTu 8988t GDSC2 4.247 9.4105 1.01 11.9303
BxPC-3 GDSC2 4.3193 11.4954 0.0337 16.9709
YAPC GDSC2 4.3301 8.683 1.4281 9.2805
SUIT-2 GDSC2 4.5238 6.7197 2.4893 2.6344
HPAF-II GDSC2 4.6591 10.4174 0.8174 12.0167
KP-2 GDSC2 4.6774 6.8993 2.4966 2.3591
SU.86.86 GDSC2 4.6838 11.2236 0.4407 13.9873
KP-1N GDSC2 4.8362 14.4711 -1.0465 20.4573
Capan-1 GDSC2 5.0488 8.854 1.8284 5.4369
AsPC-1 GDSC2 5.6381 7.7658 2.6074 0.8505
HPAC GDSC2 5.6581 14.4583 -0.4399 16.0015
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-Mes1 GDSC2 0.0401 4.2224 -0.5404 35.5054
MPP 89 GDSC2 1.1725 5.5365 0.1448 27.0002
MSTO-211H GDSC2 1.4975 4.8417 0.7791 22.2618
NCI-H28 GDSC2 2.0157 5.9613 0.8015 20.0665
NCI-H2052 GDSC2 3.5813 7.5524 1.4188 11.2532
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC2 1.842 7.4143 -0.0586 25.2531
LNCaP clone FGC GDSC2 2.3571 7.7765 0.247 21.8323
DU145 GDSC2 3.8528 7.1884 1.8113 8.1125
PC-3 GDSC2 3.9987 10.6969 0.1821 17.0788
NCI-H660 GDSC2 5.3098 6.6919 2.8727 0.2622
22Rv1 GDSC2 5.8577 11.2056 1.2394 7.2374
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2 4.8293 15.1169 -1.3713 21.7226
Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-431 GDSC2 0.2479 4.0975 -0.2726 33.3123
LOX-IMVI GDSC2 0.4189 6.5608 -1.0774 35.4754
WM1552C GDSC2 0.5798 4.9295 -0.2236 31.4442
Hs 940.T GDSC2 0.7681 5.4319 -0.2302 30.5814
VMRC-MELG GDSC2 0.8004 4.6452 0.1222 28.7864
SK-MEL-31 GDSC2 1.3299 12.2977 -2.9178 36.4719
A2058 GDSC2 1.5096 7.8722 -0.5966 28.9459
RPMI-7951 GDSC2 1.5188 3.7191 1.233 19.6277
SK-MEL-3 GDSC2 1.8036 26.7978 -9.7041 42.5607
A-388 GDSC2 1.8665 13.3414 -2.947 34.754
MZ-MEL-2 GDSC2 2.1185 8.0646 -0.1143 24.4821
SK-MEL-5 GDSC2 2.3291 7.3492 0.431 20.9634
WM115 GDSC2 2.4042 6.5821 0.8756 18.2183
CHL-1 GDSC2 2.6971 9.6783 -0.3909 23.7463
A-375 GDSC2 2.718 8.2348 0.3457 20.078
A101D GDSC2 2.7339 10.5123 -0.7744 25.2694
Hs 938.T GDSC2 2.824 10.2646 -0.5726 24.1307
IPC-298 GDSC2 3.0864 8.2168 0.6755 17.0929
WM793 GDSC2 3.0976 13.4295 -1.92 28.2473
SK-MEL-28 GDSC2 3.1289 11.075 -0.7166 23.781
WT2-iPS GDSC2 3.3814 8.9698 0.5474 16.904
CP50-MEL-B GDSC2 3.4341 12.1161 -0.9821 23.946
HT-144 GDSC2 3.5063 6.7283 1.7698 9.2896
DJM-1 GDSC2 3.6037 14.3563 -1.9622 26.9403
G-mel GDSC2 3.7459 8.2517 1.2008 12.1174
GAK GDSC2 3.869 7.2668 1.7848 8.2359
IGR-1 GDSC2 4.0563 7.3718 1.8716 7.2428
G-361 GDSC2 4.0774 14.2394 -1.5207 24.1752
HMV-II GDSC2 4.2323 10.5535 0.434 15.1519
SK-MEL-2 GDSC2 4.3225 5.7251 2.8161 1.2137
SH-4 GDSC2 4.3259 7.0169 2.2292 4.4846
MZ-MEL-7 GDSC2 4.3273 12.3966 -0.4072 19.0317
M14 GDSC2 4.4761 10.6696 0.56 13.862
LB2518-MEL GDSC2 4.5052 6.085 2.7574 1.2724
Mel Ho GDSC2 4.5403 7.9188 1.9423 5.7524
LB373-MEL-D GDSC2 4.6059 11.7584 0.1201 15.8163
COLO 800 GDSC2 4.8732 17.1127 -2.3271 24.8441
COLO 829 GDSC2 4.8886 15.0909 -1.3134 21.3621
IGR-37 GDSC2 5.0175 11.2485 0.6674 12.0086
MMAc-SF GDSC2 5.0643 11.5256 0.5658 12.4432
451Lu GDSC2 5.0665 7.3178 2.5224 1.7211
COLO 783 GDSC2 5.0768 9.907 1.352 8.0915
UACC-257 GDSC2 5.1068 7.2798 2.5582 1.5114
CP66-MEL GDSC2 5.1949 6.421 2.9255 0.1919
COLO 792 GDSC2 5.3014 20.9569 -3.9051 28.0561
Mel JuSo GDSC2 5.3533 7.3425 2.6476 0.9158
UACC-62 GDSC2 5.4013 9.5437 1.7257 5.3903
SK-MEL-24 GDSC2 5.4097 14.9531 -0.8587 18.3465
RVH-421 GDSC2 5.5675 7.0819 2.8311 0.261
SK-MEL-30 GDSC2 5.6589 21.2531 -3.7783 27.0136
COLO 679 GDSC2 5.6658 7.3708 2.7654 0.3709
WM278 GDSC2 5.7201 13.0654 0.2748 12.5126
EquiPSC Line K2 GDSC2 5.608 12.0898 0.6656 10.7559
⏷ Show the Full List of 53 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 0.4591 4.9887 -0.3751 32.6853
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EW-8 GDSC2 -0.6183 0.3721 -0.6185 39.5417
STS-0421 GDSC2 -0.2747 1.6682 -0.3045 36.237
SW982 GDSC2 0.6526 3.4815 0.3638 28.2727
G-401 GDSC2 0.8937 3.8736 0.5031 26.4157
SK-LMS-1 GDSC2 1.5426 8.5346 -0.8835 29.9451
MES-SA GDSC2 1.7616 6.7001 0.2049 24.2653
RD GDSC2 1.8385 8.7662 -0.7174 28.1637
G-402 GDSC2 1.9752 5.2656 1.0837 18.5964
GCT GDSC2 2.0938 7.1195 0.3227 22.3919
KYM-1 GDSC2 2.2013 9.2231 -0.6077 26.3884
TE 441.T GDSC2 2.6933 6.4101 1.2271 15.1441
SW872 GDSC2 2.9657 9.6018 -0.1196 21.6148
SK-UT-1 GDSC2 3.0664 7.282 1.1251 14.5487
Rh41 GDSC2 3.1362 8.6881 0.4825 18.0013
VA-ES-BJ GDSC2 3.5793 13.3222 -1.4654 25.3409
A-204 GDSC2 3.6394 9.4772 0.5047 16.3848
Rh30 GDSC2 4.191 10.3193 0.5184 14.809
HT-1080 GDSC2 4.2664 9.2928 1.0824 11.4646
RKN GDSC2 4.5072 8.8247 1.4848 8.5369
SW684 GDSC2 7.0277 20.633 -2.4736 20.7368
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 GDSC2 -0.2966 4.2277 -0.9069 38.6743
TMK-1 GDSC2 0.796 6.2349 -0.5477 31.7935
KATO III GDSC2 1.3995 3.8644 1.0542 21.1488
AGS GDSC2 1.4695 6.4617 0.0292 26.3098
RERF-GC-1B GDSC2 1.6877 5.1955 0.8232 21.2313
TGBC11TKB GDSC2 1.7129 6.2128 0.3859 23.5205
RF-48 GDSC2 1.8579 5.8049 0.7188 21.1403
IM95 GDSC2 1.8973 8.7001 -0.6304 27.5892
MKN7 GDSC2 2.2561 8.7393 -0.3192 24.9355
MKN1 GDSC2 2.4887 8.3001 0.1084 22.0785
GCIY GDSC2 2.5733 6.804 0.9235 17.3516
NUGC-3 GDSC2 2.8664 6.8641 1.1583 14.9857
SK-GT-2 GDSC2 2.9491 6.7782 1.2741 14.0211
23132/87 GDSC2 3.1627 10.7591 -0.5301 22.8787
OCUM-1 GDSC2 3.68 12.6397 -1.0421 23.4753
NUGC-4 GDSC2 3.863 5.7624 2.5179 3.7161
SNU-5 GDSC2 4.0132 5.9565 2.5266 3.3448
MKN45 GDSC2 4.2801 14.7964 -1.6376 24.0568
MKN28 GDSC2 4.3283 9.2979 1.1255 11.0632
Hs 746.T GDSC2 4.3625 9.454 1.0739 11.2783
HGC-27 GDSC2 4.7127 12.3935 -0.1134 16.69
SCH GDSC2 5.0057 14.8585 -1.1103 20.3005
ECC12 GDSC2 5.3645 14.1246 -0.4862 16.8601
NCI-N87 GDSC2 5.5034 16.4929 -1.5457 20.7872
SNU-1 GDSC2 6.1738 7.9653 2.7445 0.244
SNG-M GDSC2 3.0118 7.1567 1.1403 14.6286
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
K5 GDSC2 0.9933 7.5885 -0.9658 32.4969
BHT-101 GDSC2 1.0153 4.137 0.5429 25.6486
KMH-2 GDSC2 1.2425 5.6689 0.1589 26.6274
ML-1 [Human leukemia] GDSC2 1.5864 7.0149 -0.1146 26.5206
IHH-4 GDSC2 1.663 7.4097 -0.228 26.7409
B-CPAP GDSC2 2.5038 5.8613 1.3194 15.2382
ASH-3 GDSC2 2.9474 7.3401 0.9928 15.7081
HTC-C3 GDSC2 3.1716 7.9942 0.8593 15.7842
WRO GDSC2 3.4494 12.4657 -1.1441 24.5308
FTC-133 GDSC2 4.0089 9.8091 0.6316 14.6741
CAL-62 GDSC2 4.6228 14.3266 -1.1374 21.342
8505C GDSC2 5.2037 12.6644 0.1109 14.4435
8305C GDSC2 5.2651 13.885 -0.4407 16.8854
TT2609-C02 GDSC2 8.4051 21.4229 -1.9239 16.5028
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-27 GDSC2 -1.6613 3.2806 -2.1052 50.0057
BB30-HNC GDSC2 -0.4121 1.1928 -0.4209 37.514
HO-1-N-1 GDSC2 -0.1917 1.746 -0.2239 35.4167
BB49-HNC GDSC2 -0.0992 3.5114 -0.4651 35.9649
KON GDSC2 -0.0341 5.0955 -0.9415 37.3284
DOK GDSC2 0.0648 5.1693 -0.8651 36.5509
KOSC-2 GDSC2 0.1861 5.1165 -0.7154 35.3946
BICR 10 GDSC2 0.5377 4.8224 -0.2264 31.6611
JHU-029 GDSC2 0.5565 5.6126 -0.527 32.8327
Detroit 562 GDSC2 0.6213 6.1626 -0.6952 33.1778
JHU-011 GDSC2 0.6407 6.5483 -0.8451 33.639
PCI-15A GDSC2 0.6498 4.4455 0.0369 29.9091
CAL-33 GDSC2 0.6807 4.0284 0.2198 28.8673
HSC-3 GDSC2 0.8046 4.0346 0.3516 27.6163
BICR 22 GDSC2 0.9194 4.812 0.1831 27.9384
PCI-06A GDSC2 1.1627 4.9184 0.3966 25.7622
SCC-4 GDSC2 1.2417 7.0554 -0.4721 29.5275
PCI-04B GDSC2 1.6887 7.1978 -0.1021 26.0555
HSC-2 GDSC2 1.9491 10.7215 -1.5761 30.8423
FaDu GDSC2 2.0993 8.1413 -0.1696 24.8132
OSC-19 GDSC2 2.1279 8.1001 -0.1229 24.4885
SCC-9 GDSC2 2.1708 9.6546 -0.8484 27.4751
BHY GDSC2 2.5381 8.558 0.0251 22.3234
SAS GDSC2 2.6542 6.8573 0.971 16.7986
Ca9-22 GDSC2 2.9131 7.0022 1.1309 14.999
JHU-022 GDSC2 3.6616 11.9865 -0.7307 22.262
SCC-15 GDSC2 4.0081 9.1391 0.9635 12.809
PE/CA-PJ15 GDSC2 4.211 12.2419 -0.4205 19.3974
NCI-H3118 GDSC2 4.3007 9.3348 1.0871 11.3532
OSC-20 GDSC2 4.4013 12.3963 -0.3501 18.5804
HSC-4 GDSC2 4.7183 10.4056 0.8656 11.6112
SAT [Human HNSCC] GDSC2 4.7525 12.0337 0.0932 15.59
SKN-3 GDSC2 4.9729 15.1292 -1.2686 20.9899
BICR 31 GDSC2 5.0826 15.5257 -1.382 21.1557
UPCI-SCC-090 GDSC2 5.4077 10.901 1.0978 8.8454
SCC-25 GDSC2 5.721 8.5705 2.3249 1.8997
LB771-HNC GDSC2 5.7251 13.0368 0.2919 12.418
BICR 78 GDSC2 5.987 9.8617 1.9151 3.5143
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RT-112 GDSC2 0.5324 5.3898 -0.4595 32.6761
KU-19-19 GDSC2 1.2233 8.3261 -1.0892 31.9673
SW1710 GDSC2 1.4427 6.0625 0.1857 25.6482
BFTC-905 GDSC2 1.7176 6.6692 0.1765 24.5821
T24 GDSC2 2.8871 8.6516 0.2865 19.8341
CAL-29 GDSC2 3.0226 5.7253 1.8625 10.1444
639V GDSC2 3.3957 7.7186 1.1848 13.1988
5637 GDSC2 3.4783 8.6223 0.8009 15.2034
RT-4 GDSC2 3.6355 11.3327 -0.4253 21.0078
HT-1197 GDSC2 4.5325 10.9799 0.4491 14.3125
647V GDSC2 4.6371 9.627 1.1868 9.9817
SW780 GDSC2 4.7122 6.8091 2.5553 2.0057
TCCSUP GDSC2 5.2688 11.5077 0.7159 11.1986
HT-1376 GDSC2 5.5379 17.0463 -1.7925 21.5805
J82 GDSC2 6.3984 15.4079 -0.3894 14.2395
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JAR GDSC2 -0.9892 4.1019 -1.6169 44.6816
SW954 GDSC2 -0.8984 2.9155 -1.1795 43.1939
CAL-39 GDSC2 -0.5298 1.6916 -0.5736 38.8507
PA-1 GDSC2 -0.3878 3.3663 -0.7388 38.644
TC-YIK GDSC2 -0.3782 1.9173 -0.437 37.4043
BPH-1 GDSC2 0.2929 6.6052 -1.2262 36.5454
DoTc2 4510 GDSC2 0.4255 7.6381 -1.5539 36.8548
PWR-1E GDSC2 0.6315 3.5535 0.3194 28.6004
OVCA433 GDSC2 0.6326 4.5219 -0.0101 30.2145
ACC-OV7 GDSC2 0.9112 6.3059 -0.4616 30.9201
NEC8 GDSC2 1.5627 5.7811 0.4342 23.8702
OVMIU GDSC2 1.6386 4.3548 1.1271 19.7071
JEG-3 GDSC2 1.8314 11.5848 -2.1091 32.824
SKN GDSC2 1.8324 4.3267 1.3433 17.6572
LB831-BLC GDSC2 1.8694 6.911 0.2089 23.8265
SKG-IIIa GDSC2 2.285 7.7776 0.1803 22.4309
OV17R GDSC2 2.5282 7.6673 0.4569 20.1269
ME-180 GDSC2 3.3223 15.7739 -2.9037 30.3759
Ca Ski GDSC2 3.4835 8.541 0.8458 14.9321
HeLa GDSC2 3.5602 15.2182 -2.4288 28.4604
JHOS-3 GDSC2 3.6135 9.5872 0.4289 16.8667
OMC-1 [Human cervical carcinoma] GDSC2 3.6344 7.603 1.4359 11.0024
MS751 GDSC2 3.6359 9.6711 0.4051 16.9295
C-4-I GDSC2 3.6511 7.4014 1.5496 10.2591
PEO1 GDSC2 3.6733 11.0721 -0.2644 20.1625
SW962 GDSC2 3.7225 7.5964 1.5087 10.3181
HEY GDSC2 3.7307 7.7686 1.4294 10.7804
DSH1 GDSC2 3.8221 6.6472 2.0555 6.6723
HT-3 GDSC2 4.0792 9.3148 0.9308 12.8115
SiHa GDSC2 4.7478 9.955 1.1054 10.1967
C-33 A GDSC2 4.7529 14.9401 -1.342 21.7998
SW756 GDSC2 4.7598 7.8483 2.1152 4.3285
UWB1.289 GDSC2 5.0082 11.8532 0.3669 13.6056
HEC-1 GDSC2 5.1559 9.8487 1.4311 7.4863
SiSo GDSC2 5.4178 9.7889 1.6232 5.9258
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug

References

1 Effects of the JAK2 inhibitor, AZ960, on Pim/BAD/BCL-xL survival signaling in the human JAK2 V617F cell line SET-2. J Biol Chem. 2008 Nov 21;283(47):32334-43.