Details of the Drug

General Information of Drug (ID: DM9BQTX)

Drug Name
PIK-75
Synonyms PIK75; PIK 75; imidazopyridine derivative 8c [PMID 17601739]
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 452.3
Logarithm of the Partition Coefficient (xlogp) 3.8
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 0
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C16H14BrN5O4S
IUPAC Name
N-[(E)-(6-bromoimidazo[1,2-a]pyridin-3-yl)methylideneamino]-N,2-dimethyl-5-nitrobenzenesulfonamide
Canonical SMILES
CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N(C)/N=C/C2=CN=C3N2C=C(C=C3)Br
InChI
InChI=1S/C16H14BrN5O4S/c1-11-3-5-13(22(23)24)7-15(11)27(25,26)20(2)19-9-14-8-18-16-6-4-12(17)10-21(14)16/h3-10H,1-2H3/b19-9+
InChIKey
QTHCAAFKVUWAFI-DJKKODMXSA-N
Cross-matching ID
PubChem CID
10275789
ChEBI ID
CHEBI:94827
CAS Number
945619-31-8
UNII
9058I8S63D
DrugBank ID
DB17047
TTD ID
D00HSJ
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
DNA-dependent protein kinase catalytic (PRKDC) TTK3PY9 PRKDC_HUMAN Inhibitor [2]
PI3-kinase beta (PIK3CB) TTTHBCA PK3CB_HUMAN Inhibitor [3]
PI3-kinase gamma (PIK3CG) TTHBTOP PK3CG_HUMAN Inhibitor [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Forkhead box protein O3 (FOXO3) OTHXQG4P FOXO3_HUMAN Protein Interaction/Cellular Processes [4]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
PI3-kinase gamma (PIK3CG) DTT PIK3CG 1.98E-01 -0.05 -0.55
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U2OS CTRP1 -2.251 0.9031 -3.5382 17.5488
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MCF-7 CTRP1 -3.893 -0.6619 -4.4684 33.8019
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LN-229 CTRP1 -4.0699 -1.1161 -4.4903 35.2297
SF295 CTRP1 7.3394 8.6505 4.7875 0.2368
GaMG CTRP1 7.3893 8.94 4.7043 0.2314
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP1 -5.0519 -3.6737 -5.0588 46.6125
HEC-151 CTRP1 -3.8895 -1.8827 -4.0567 31.1687
HEC-6 CTRP1 7.1176 8.4029 4.7929 0.3142
HEC-265 CTRP1 7.1228 8.2522 4.847 0.1753
HEC-108 CTRP1 7.1239 8.2549 4.8465 0.0908
HEC-59 CTRP1 7.2528 8.5575 4.7884 0.1378
HEC-251 CTRP1 7.5203 8.7216 4.8265 0.1132
MFE-319 CTRP1 7.5281 9.1684 4.6755 0.4672
KLE CTRP1 7.612 9.2354 4.6832 0.2065
Ishikawa (Heraklio) 02 ER- CTRP1 6.4833 7.4146 4.9053 0.1508
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NOMO-1 CTRP1 -5.8104 -2.5571 -5.9945 56.1255
OCI-AML-3 CTRP1 -5.5719 -4.2407 -5.5742 53.989
WSU-DLCL2 CTRP1 -5.2794 -4.2298 -5.2801 49.837
SKM-1 CTRP1 -5.2295 -4.6224 -5.2296 49.1241
PL21 CTRP1 -5.1603 -3.1584 -5.2044 48.214
GDM-1 CTRP1 -5.1007 -3.1223 -5.1452 47.3934
THP-1 CTRP1 -4.9006 -3.9142 -4.9015 44.4303
NU-DUL-1 CTRP1 -4.8133 -3.9368 -4.8138 43.181
SU-DHL-4 CTRP1 -4.7576 -2.5611 -4.8554 42.8473
MOLM-16 CTRP1 -4.3901 -2.8315 -4.4256 37.3686
U-937 CTRP1 -4.2506 -2.6971 -4.2929 35.4291
SU-DHL-5 CTRP1 -4.169 -2.385 -4.2514 34.5379
KMS-11 CTRP1 -4.0652 -2.156 -4.1836 33.3112
EJM CTRP1 -4.0597 -1.1146 -4.4798 35.0937
RPMI-8226 CTRP1 -3.5349 -1.5229 -3.7736 26.6884
LP-1 CTRP1 -2.7359 -1.4779 -2.922 14.9372
OCI-Ly10 CTRP1 -1.0719 2.9727 -3.6033 13.1966
AMO1 CTRP1 -0.9744 12.6806 -8.3579 33.6839
MC116 CTRP1 5.6323 7.4552 4.4165 5.5735
BL-70 CTRP1 6.6937 7.6511 4.9003 0.1046
HT CTRP1 7.1578 8.3171 4.8372 0.1855
Ku812 CTRP1 7.2193 8.8184 4.6823 0.637
P3HR-1 CTRP1 7.2967 8.6745 4.7637 0.3154
KE-97 CTRP1 7.4731 8.7686 4.7944 0.1793
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RCC10RGB CTRP1 -1.9552 7.7854 -6.7167 32.803
VMRC-RCW CTRP1 7.5766 9.1436 4.7023 0.3621
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-175 CTRP1 -8.2352 -5.4094 -8.2522 82.9927
LS411N CTRP1 -6.5398 8.4702 -8.6311 76.5739
HCT 116 CTRP1 -5.4205 -2.8897 -5.5151 51.6819
DLD-1 CTRP1 -5.2338 4.4894 -5.9994 81.811
COLO205 CTRP1 -5.0468 3.8615 -5.6463 83.0026
CL-34 CTRP1 -4.7919 -1.9978 -5.0118 43.7443
SNU-C4 CTRP1 -4.754 -1.9358 -4.9862 43.2936
LS180 CTRP1 -4.4707 -1.9461 -4.6746 39.4268
RCM-1 [Human ESC] CTRP1 -4.3169 -1.3993 -4.6637 38.0825
SNU-C5 CTRP1 -4.2605 -1.289 -4.6381 37.4993
SW480 CTRP1 -4.116 -0.3388 -4.8325 37.2962
HT115 CTRP1 -3.7883 0.0163 -4.6354 33.9795
GP2d CTRP1 -3.681 -1.5071 -3.6812 98.051
SW948 CTRP1 -3.6681 -0.0055 -4.5014 32.4293
SNU-1040 CTRP1 -3.6585 -1.5843 -3.889 28.3686
COLO 320 CTRP1 -3.6071 1.686 -5.2047 35.4311
KM12 CTRP1 -3.5987 -1.3441 -3.9017 28.057
LoVo CTRP1 -3.5855 -1.2206 -3.9302 28.1742
SNU-81 CTRP1 -3.5572 -0.5224 -4.1685 29.6373
HCT 8 CTRP1 -3.5371 1.9474 -5.2592 35.2273
HT-55 CTRP1 -3.3422 -0.3999 -3.9947 27.0609
SW48 CTRP1 -3.3348 0.6036 -3.365 91.1915
SNU-61 CTRP1 -3.3148 -0.9286 -3.749 25.0803
MDST8 CTRP1 -3.2481 -1.3966 -3.504 22.7673
CW-2 CTRP1 -3.2157 -0.5453 -3.8014 24.8619
SW620 CTRP1 -3.1707 -0.4824 -3.7816 24.4383
LS513 CTRP1 -3.1662 1.5031 -3.2472 87.803
NCI-H508 CTRP1 -3.1239 -0.5043 -3.7237 23.7153
SK-CO-1 CTRP1 -3.0467 5.1519 -3.7851 76.8067
CL-40 CTRP1 -3.0465 -0.7583 -3.5353 21.775
COLO 678 CTRP1 -3.0463 0.8273 -4.2516 27.0377
RKO CTRP1 -3.0087 -0.929 -3.4249 20.6646
LS123 CTRP1 -2.2081 2.542 -4.3141 23.0948
C2BBe1 CTRP1 -1.8302 31.109 -13.9906 55.8492
HT-29 CTRP1 -1.1185 2.6549 -3.4813 12.3899
SNU-C2A CTRP1 7.8043 10.9652 4.0985 3.1067
SW403 CTRP1 7.8562 10.0949 4.466 1.0439
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-398 CTRP1 -3.8711 -1.2553 -4.227 32.1781
Hep-G2 CTRP1 -1.7627 2.1256 -3.7257 16.8513
JHH-6 CTRP1 6.4862 7.3277 4.9372 0.0988
SNU-449 CTRP1 7.9764 9.8602 4.5983 0.2454
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LC-1/sq-SF CTRP1 -6.1313 2.829 -6.6078 86.2389
NCI-H1373 CTRP1 -5.5026 1.9889 -5.7852 87.9266
NCI-H2122 CTRP1 -5.3881 -4.4611 -5.3883 51.3886
HCC78 CTRP1 -5.2771 2.3928 -5.6072 86.775
NCI-H596 CTRP1 -4.8634 -1.9107 -5.1121 44.7457
EBC-1 CTRP1 -4.7635 20.3758 -11.7184 63.6794
NCI-H661 CTRP1 -4.6018 1.799 -4.796 87.976
HCC1833 CTRP1 -4.3199 -1.2455 -4.7169 38.3631
SK-LU-1 CTRP1 -4.1449 -1.1764 -4.5506 36.1334
NCI-H1793 CTRP1 -4.1337 19.4057 -10.6438 63.1978
CAL-12T CTRP1 -4.0463 0.4641 -5.0948 37.8837
NCI-H1781 CTRP1 -4.0199 -1.5282 -4.3 33.7283
NCI-H2342 CTRP1 -4.008 0.424 -5.038 37.3874
NCI-H1755 CTRP1 -3.9759 -0.8286 -4.4932 34.5441
SCLC-21H CTRP1 -3.9393 -0.9004 -4.4273 33.8999
LCLC-103H CTRP1 -3.9383 1.5163 -4.0599 88.418
HCC44 CTRP1 -3.7851 1.1681 -3.867 89.4604
NCI-H1963 CTRP1 -3.7546 -1.3997 -4.0522 30.1878
HCC827 CTRP1 -3.7188 -1.7151 -3.916 28.9767
HARA [Human squamous cell lung carcinoma] CTRP1 -3.7132 -1.6871 -3.7133 98.4571
NCI-H2073 CTRP1 -3.6556 -0.9695 -4.0971 29.8163
NCI-H1876 CTRP1 -3.5473 -0.6941 -4.0886 29.0343
SHP-77 CTRP1 -3.5392 -2.2694 -3.5392 99.6086
NCI-H441 CTRP1 -3.5084 0.9031 -4.7437 32.7023
NCI-H2141 CTRP1 -3.4733 0.3345 -4.4506 30.8618
HCC33 CTRP1 -3.4717 0.4996 -3.5011 91.6242
NCI-H1836 CTRP1 -3.4233 -0.5546 -4.0146 27.7147
HCC2108 CTRP1 -3.3705 -1.7129 -3.5367 23.8104
NCI-H358 CTRP1 -3.3523 4.3386 -3.9116 79.4149
NCI-H2126 CTRP1 -3.3296 -1.7071 -3.3296 98.7628
COR-L23 CTRP1 -3.2188 0.3187 -4.1863 27.6216
HCC1195 CTRP1 -3.2111 -0.2647 -3.9175 25.6958
NCI-H1694 CTRP1 -3.1584 -0.9759 -3.5643 22.6807
NCI-H727 CTRP1 -3.1463 1.228 -3.2053 88.7762
NCI-H1105 CTRP1 -3.1342 -1.6587 -3.295 20.4053
Lu-99 CTRP1 -2.9639 0.3829 -2.9781 91.823
HCC4006 CTRP1 -2.9078 -1.0642 -3.2637 18.7553
HCC15 CTRP1 -2.8991 0.6264 -4.0132 24.5691
HCC1359 CTRP1 -2.8984 -0.9641 -3.2946 18.9527
NCI-H2081 CTRP1 -2.8962 0.1882 -3.8046 23.0119
NCI-H841 CTRP1 -2.8913 -1.662 -3.0293 16.7672
DV-90 CTRP1 -2.8049 3.1287 -3.0693 81.7618
NCI-H3255 CTRP1 -2.7751 1.085 -4.1134 24.5937
NCI-H522 CTRP1 -2.763 0.8479 -2.7885 89.842
COR-L51 CTRP1 -2.747 12.017 -9.5069 40.8456
COLO 699 CTRP1 -2.6847 -1.0708 -3.0263 15.4879
NCI-H2030 CTRP1 -2.6396 -0.458 -3.2508 17.1226
NCI-H460 CTRP1 -2.4909 -1.2177 -2.7623 12.1642
HCC2935 CTRP1 -2.2924 0.5352 -3.3944 16.5549
T3M-10 CTRP1 -2.142 6.1527 -6.0589 31.3961
Sq-1 CTRP1 -2.1082 -1.2994 -2.3335 6.3854
NCI-H2023 CTRP1 -1.8734 0.2308 -2.8712 10.0748
NCI-H2172 CTRP1 -1.6682 -0.603 -2.2859 3.98
A-549 CTRP1 -1.6192 48.0729 -22.149 53.6655
BEN CTRP1 0.0208 30.2845 -11.8772 53.0446
NCI-H2110 CTRP1 0.3871 12.3443 -7.1356 26.6693
Lu-65 CTRP1 0.9192 121.4249 -56.5111 50.36
NCI-H23 CTRP1 1.5755 89.1771 -39.8398 50.0838
NCI-H1437 CTRP1 2.3014 86.0072 -37.6377 49.6117
NCI-H1975 CTRP1 3.3133 33.5053 -10.5481 47.1007
NCI-H1568 CTRP1 3.8088 47.1944 -16.9613 47.3512
NCI-H1944 CTRP1 4.3616 33.57 -9.6834 45.0567
NCI-H2009 CTRP1 4.4827 27.9203 -6.7571 43.5927
NCI-H810 CTRP1 5.3235 32.7274 -8.4546 42.8515
NCI-H1792 CTRP1 5.7716 43.1068 -13.2729 44.0722
NCI-H1930 CTRP1 6.125 8.9035 4.0585 3.6777
NCI-H650 CTRP1 6.8251 8.5478 4.6176 1.3424
COR-L88 CTRP1 7.1426 9.0362 4.5675 1.2414
NCI-H2286 CTRP1 7.2594 8.7203 4.7336 0.2191
COR-L279 CTRP1 7.3023 8.6553 4.7724 0.2891
Calu-6 CTRP1 7.3255 8.7442 4.7498 0.3416
NCI-H2029 CTRP1 7.3276 8.8642 4.708 0.4719
VMRC-LCD CTRP1 7.3342 8.866 4.7099 0.4618
COLO 668 CTRP1 7.3708 9.0351 4.6629 0.3123
NCI-H1915 CTRP1 7.3899 8.9704 4.6937 0.2494
NCI-H82 CTRP1 7.3986 8.8988 4.7225 0.3872
NCI-H1573 CTRP1 7.4155 8.9762 4.7014 0.4445
KNS-62 CTRP1 7.4557 8.9339 4.7313 0.3351
RERF-LC-KJ CTRP1 7.4696 8.978 4.721 0.1844
NCI-H1435 CTRP1 7.4702 8.8787 4.7557 0.1367
NCI-H1048 CTRP1 7.4971 9.1107 4.6843 0.4554
EPLC-272H CTRP1 7.54 9.4816 4.5659 0.8719
LXF 289 CTRP1 7.5544 9.3913 4.6051 0.3614
DMS 273 CTRP1 7.5925 9.1385 4.71 0.3342
LCLC-97TM1 CTRP1 7.603 9.5303 4.5733 0.7924
Calu-3 CTRP1 7.6541 9.428 4.6306 0.545
ChaGo-K-1 CTRP1 7.755 9.6355 4.5946 0.609
NCI-H1355 CTRP1 7.8322 9.6323 4.6251 0.4669
NCI-H2405 CTRP1 7.8776 10.2524 4.4155 1.2533
NCI-H1666 CTRP1 8.009 11.6013 3.935 3.8162
NCI-H1299 CTRP1 8.2643 9.8455 4.7055 0.1463
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-450 CTRP1 7.3435 8.4396 4.8602 0.0982
KYSE-410 CTRP1 7.9415 9.5366 4.6979 0.238
KYSE-140 CTRP1 8.4093 10.5159 4.528 0.4779
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COV434 CTRP1 -5.655 -3.2939 -5.7124 54.8101
TYK-nu CTRP1 -4.6208 -2.5874 -4.7039 40.8892
OVKATE CTRP1 -4.5326 -2.5542 -4.6144 39.6521
OVCAR-8 CTRP1 -4.3841 -2.0847 -4.5465 38.0308
RMUG-S CTRP1 -4.3565 -1.434 -4.6958 38.5639
A2780 CTRP1 -4.2972 -2.3727 -4.3921 36.4274
SNU-840 CTRP1 -3.9772 -1.0662 -4.4078 34.064
COV644 CTRP1 -3.7636 0.4446 -4.7956 34.6209
OVK18 CTRP1 -3.6402 -1.1127 -4.0279 29.2351
RMG-I CTRP1 -3.4339 3.6473 -5.9767 37.1306
Caov-3 CTRP1 -3.246 -0.0907 -4.0298 26.7141
IGROV-1 CTRP1 -3.2139 0.1071 -4.0855 26.9072
JHOC-5 CTRP1 -3.0748 -2.2243 -3.1019 18.5388
JHOM-1 CTRP1 -3.0189 -1.2692 -3.3025 19.7407
OV-90 CTRP1 -2.9804 0.1603 -3.8752 24.0216
COV362 CTRP1 -2.4573 1.6129 -4.0757 22.6767
OVCAR-4 CTRP1 -2.3933 3.0412 -4.7257 26.4918
EFO-27 CTRP1 -2.3388 0.1878 -3.2671 15.702
OV7 CTRP1 -2.0234 2.8579 -4.3118 22.2287
OAW42 CTRP1 -1.1947 0.5909 -2.529 4.5519
COV318 CTRP1 6.8685 7.8143 4.9066 0.0664
OVMANA CTRP1 6.9024 8.3057 4.7446 0.3206
EFO-21 CTRP1 6.9293 9.1111 4.437 2.3084
HEY A8 CTRP1 7.1741 8.5297 4.7692 0.3576
SK-OV-3 CTRP1 7.4433 9.1509 4.6492 0.6094
JHOS-4 CTRP1 7.7431 9.7094 4.5632 0.3771
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CFPAC-1 CTRP1 -6.1206 13.0378 -9.9159 70.8238
Panc 10.05 CTRP1 -4.0231 5.5726 -4.9677 77.7973
HPAC CTRP1 -1.3765 37.1033 -16.5112 54.3792
PaTu 8902 CTRP1 7.2237 8.5285 4.7879 0.1446
SUIT-2 CTRP1 7.2502 8.593 4.7751 0.3043
Capan-2 CTRP1 7.3637 11.9597 3.416 8.7493
HuP-T4 CTRP1 7.3757 9.0097 4.6741 0.5618
QGP-1 CTRP1 7.4538 8.7078 4.8083 0.1582
Panc 03.27 CTRP1 7.5105 8.9138 4.7581 0.2453
KP-3 CTRP1 8.0816 10.2156 4.5113 0.7023
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 CTRP1 6.1169 28.546 -5.7115 39.4683
MSTO-211H CTRP1 7.826 9.6093 4.6309 0.4524
NCI-H2052 CTRP1 8.0676 9.7712 4.6624 0.2741
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaCa-3 CTRP1 7.2474 8.3283 4.8645 0.0571
Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-375 CTRP1 -4.0633 -1.9637 -4.2259 33.578
COLO 741 CTRP1 -3.5625 -0.5712 -3.5668 95.3493
SK-MEL-1 CTRP1 -3.1655 0.7641 -4.3389 28.2932
SK-MEL-5 CTRP1 -2.6652 -1.3081 -2.9096 14.4073
SK-MEL-28 CTRP1 -1.8548 -1.4092 -2.0372 2.5003
Hs 936.T CTRP1 6.8549 8.4724 4.6608 1.0686
Hs 852.T CTRP1 7.1296 8.8253 4.6431 0.4531
G-361 CTRP1 7.4798 8.8699 4.7622 0.2464
Hs 944.T CTRP1 7.8619 9.332 4.7394 0.1796
⏷ Show the Full List of 9 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT-1080 CTRP1 -4.178 -1.2064 -4.5762 36.5279
RKN CTRP1 -3.5975 -1.4471 -3.8661 27.7899
G-401 CTRP1 8.1343 10.3126 4.4967 0.7216
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AGS CTRP1 -6.4974 0.2226 -7.5896 58.8265
SH-10-TC CTRP1 7.24 8.3603 4.8513 0.1345
Fu97 CTRP1 7.3477 8.8294 4.728 0.396
NUGC-4 CTRP1 7.7069 9.3313 4.6845 0.3543
MKN7 CTRP1 8.0099 9.7708 4.6419 0.3425
MKN74 CTRP1 8.1075 9.7364 4.6882 0.1083
SNG-M CTRP1 7.5999 8.9393 4.7809 0.088
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-9 CTRP1 -4.8087 -1.2468 -5.2474 44.5522
HSC-2 CTRP1 6.9999 8.0868 4.86 0.1869
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RT-4 CTRP1 7.4 9.0321 4.6754 0.5419
HT-1376 CTRP1 7.5312 9.4618 4.5697 0.8628
KMBC-2 CTRP1 7.6202 9.1518 4.7154 0.3086
5637 CTRP1 7.9324 9.7548 4.6192 0.4362
UM-UC-3 CTRP1 7.9907 9.3851 4.7656 0.1125

References

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