Details of the Drug

General Information of Drug (ID: DM9C8NX)

Drug Name
Trichostatin A
Synonyms
trichostatin A; 58880-19-6; Trichostatin A (TSA); TSA; Trichostatin; Tricostatin A; UNII-3X2S926L3Z; CHEBI:46024; (2E,4E,6R)-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide; GNF-PF-1011; RTKIYFITIVXBLE-QEQCGCAPSA-N; 3X2S926L3Z; 7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide; 2,4-Heptadienamide, 7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-; 7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6-DIMETHYL-7-OXO-2,4-HEPTADIENAMIDE
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 302.37
Logarithm of the Partition Coefficient (xlogp) 2.7
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 4
Chemical Identifiers
Formula
C17H22N2O3
IUPAC Name
(2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide
Canonical SMILES
C[C@H](/C=C(\\C)/C=C/C(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C
InChI
InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1
InChIKey
RTKIYFITIVXBLE-QEQCGCAPSA-N
Cross-matching ID
PubChem CID
444732
ChEBI ID
CHEBI:46024
CAS Number
58880-19-6
UNII
3X2S926L3Z
DrugBank ID
DB04297
TTD ID
D0NF6F
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histone deacetylase (HDAC) TTBH0VX NOUNIPROTAC Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma (AGPAT3) OTAUR5TG PLCC_HUMAN Gene/Protein Processing [3]
1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 (PNPLA3) OTR4990X PLPL3_HUMAN Gene/Protein Processing [3]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (PLCB1) OT9HYT7A PLCB1_HUMAN Gene/Protein Processing [4]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (PLCB4) OTPA0QHW PLCB4_HUMAN Gene/Protein Processing [3]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (PLCE1) OTJISZOX PLCE1_HUMAN Gene/Protein Processing [3]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (PLCH1) OT6Z1L2E PLCH1_HUMAN Gene/Protein Processing [3]
11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2) OTHF4H9U DHI2_HUMAN Gene/Protein Processing [3]
14-3-3 protein eta OTP8NJFJ 1433F_HUMAN Gene/Protein Processing [4]
14-3-3 protein sigma (SFN) OTLJCZ1U 1433S_HUMAN Gene/Protein Processing [3]
15-hydroxyprostaglandin dehydrogenase (HPGD) OTYZI6JB PGDH_HUMAN Gene/Protein Processing [5]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 1.5652 3.6494 -0.7133 2.1525
U2OS GDSC1 -4.848 -3.6988 -4.8481 61.0112
EW-13 GDSC1 -4.7707 -3.0557 -4.774 59.9202
EW-22 GDSC1 -4.5375 -3.0541 -4.539 57.1031
ES7 GDSC1 -4.4568 -3.0713 -4.4578 56.1134
ES1 GDSC1 -4.4349 -3.1232 -4.4355 55.8475
NOS-1 [Human HNSCC] GDSC1 -4.0252 -2.3036 -4.0339 50.7335
EW-3 GDSC1 -3.5984 -1.5524 -3.6354 45.5347
EW-7 GDSC1 -3.5721 -1.7888 -3.591 45.1524
SK-PN-DW GDSC1 -3.5368 -2.1664 -3.5409 44.6572
HOS GDSC1 -3.4429 -1.4394 -3.4823 43.6337
HuO9 GDSC1 -3.4312 -2.2078 -3.4334 43.3291
SK-ES-1 GDSC1 -3.1525 -1.4912 -3.1745 39.9561
TC-71 GDSC1 -3.1046 -2.1367 -3.1053 39.2392
CADO-ES1 GDSC1 -2.9332 -1.1453 -2.9745 37.3329
EW-18 GDSC1 -2.8517 -0.7088 -2.948 36.6265
MHH-ES-1 GDSC1 -2.8458 -1.4505 -2.8593 36.0828
EW-16 GDSC1 -2.7898 -1.5162 -2.7986 35.3545
ES8 GDSC1 -2.5875 -0.9552 -2.6299 33.0333
NY GDSC1 -2.551 -0.861 -2.6026 32.6344
ES4 GDSC1 -2.4108 -0.7024 -2.475 30.9647
SaOS-2 GDSC1 -2.3899 -1.2462 -2.3997 30.3624
CAL-72 GDSC1 -1.5414 0.2295 -1.7423 21.0251
A-673 GDSC1 -1.5251 0.836 -1.9381 22.2862
CAL-78 GDSC1 -1.4374 -0.1521 -1.5251 18.9637
MG-63 GDSC1 -1.4018 1.9215 -2.2688 23.8897
EW-24 GDSC1 -1.251 0.4245 -1.4915 17.6846
SJSA-1 GDSC1 -1.1847 0.2403 -1.3575 16.388
CHSA8926 GDSC1 -0.7225 0.0353 -0.7918 9.9138
HuO-3N1 GDSC1 -0.6933 1.2101 -1.2326 12.9783
ES6 GDSC1 -0.5028 1.3014 -1.0882 11.0094
G-292 clone A141B1 GDSC1 -0.3054 1.4142 -0.9558 9.1314
EW-1 GDSC1 -0.1151 4.2575 -2.2031 17.7168
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 152 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 -5.2687 -4.1612 -5.2688 66.2573
Karpas-231 GDSC1 -7.0358 -5.7884 -7.0358 87.1149
SU-DHL-10 GDSC1 -6.9999 -5.9084 -6.9999 87.0961
NK-92MI GDSC1 -6.7541 -5.1315 -6.7543 83.2197
CML-T1 GDSC1 -6.4098 -3.7513 -6.4216 76.9331
Karpas-45 GDSC1 -5.8801 -4.4728 -5.8803 73.6275
RCH-ACV GDSC1 -5.741 -4.4905 -5.7411 72.0493
SU-DHL-6 GDSC1 -5.4432 -4.4371 -5.4432 68.4446
Jurkat GDSC1 -5.0857 -3.1823 -5.0903 63.645
SU-DHL-8 GDSC1 -5.0286 -4.0763 -5.0286 63.2788
SU-DHL-5 GDSC1 -4.9312 -4.0645 -4.9312 62.0651
QIMR-WIL GDSC1 -4.8593 -2.7847 -4.8699 60.8036
LC4-1 GDSC1 -4.788 -3.1154 -4.7907 60.1489
MOLT-13 GDSC1 -4.7113 -2.4038 -4.734 58.8822
MY-M12 GDSC1 -4.7092 -2.3131 -4.737 58.7959
SU-DHL-16 GDSC1 -4.682 -3.5677 -4.6821 58.9439
RPMI-8866 GDSC1 -4.6807 -2.1397 -4.7192 58.3589
HAL-01 GDSC1 -4.6327 -3.2675 -4.6333 58.3039
Ku812 GDSC1 -4.5997 -2.8693 -4.6041 57.8151
Loucy GDSC1 -4.5966 -3.4373 -4.5968 57.8751
RPMI-8226 GDSC1 -4.5544 -3.5835 -4.5545 57.3558
DoHH2 GDSC1 -4.4447 -2.8236 -4.4481 55.9305
OCI-AML-2 GDSC1 -4.4153 -3.0755 -4.4161 55.6016
H9 GDSC1 -4.3826 -3.8192 -4.3826 55.2108
WIL2 NS GDSC1 -4.3009 -2.8626 -4.3026 54.1692
P32/ISH GDSC1 -4.2934 -2.7768 -4.296 54.0689
MOLT-16 GDSC1 -4.2663 -3.1965 -4.2665 53.7547
P30/OHK GDSC1 -4.2161 -2.3066 -4.229 53.0656
JSC-1 GDSC1 -4.1721 -2.9811 -4.1726 52.5763
GA-10 GDSC1 -4.1428 -2.523 -4.1479 52.1929
BL-41 GDSC1 -4.1162 -3.1057 -4.1163 51.8791
MOLP-8 GDSC1 -3.9953 -3.0733 -3.9953 50.3687
ST486 GDSC1 -3.9675 -2.047 -3.9853 50.0213
TK [Human B-cell lymphoma] GDSC1 -3.9501 -2.364 -3.9559 49.8058
EJM GDSC1 -3.9005 -0.449 -4.1382 49.3024
SUP-B15 GDSC1 -3.8955 -2.4725 -3.8985 49.1254
Karpas-620 GDSC1 -3.8468 -2.3762 -3.8508 48.5203
MLMA GDSC1 -3.8372 -2.3731 -3.8412 48.4008
CA46 GDSC1 -3.8128 -2.6623 -3.8135 48.0902
KE-37 GDSC1 -3.7608 -2.3583 -3.7641 47.4477
NU-DUL-1 GDSC1 -3.7237 -3.025 -3.7237 46.9742
NALM-6 GDSC1 -3.7198 -2.7095 -3.72 46.9258
PF-382 GDSC1 -3.6955 -2.776 -3.6956 46.6216
Sc-1 GDSC1 -3.6809 -2.5851 -3.6815 46.4418
KMOE-2 GDSC1 -3.6726 -1.8993 -3.6888 46.3882
ATN-1 GDSC1 -3.6482 -2.3766 -3.6502 46.0383
TUR GDSC1 -3.5464 -0.9833 -3.65 45.093
SUP-HD1 GDSC1 -3.5383 -1.8129 -3.5547 44.7244
KOPN-8 GDSC1 -3.5347 -2.4349 -3.5355 44.6162
MOLT-4 GDSC1 -3.477 -2.1929 -3.4799 43.905
DB GDSC1 -3.4682 -1.3005 -3.5233 44.0008
RPMI-6666 GDSC1 -3.4645 -1.7001 -3.4848 43.8247
697 GDSC1 -3.4286 -2.7574 -3.4286 43.2856
IM-9 GDSC1 -3.3805 -1.303 -3.4302 42.9065
HC-1 GDSC1 -3.3104 -2.1986 -3.3118 41.8158
Reh GDSC1 -3.2337 -1.3386 -3.2718 41.045
DEL GDSC1 -3.2129 -2.2065 -3.2137 40.5935
MC116 GDSC1 -3.1773 -2.6673 -3.1773 40.144
ALL-PO GDSC1 -3.1394 -1.7427 -3.148 39.7203
ALL-SIL GDSC1 -3.1219 -1.8222 -3.1276 39.4851
KY821 GDSC1 -3.0904 -1.8872 -3.094 39.0796
U266B1 GDSC1 -3.0485 -1.9497 -3.0506 38.5468
MHH-PREB-1 GDSC1 -3.0353 -1.6056 -3.0469 38.4375
DND-41 GDSC1 -3.0285 -2.0827 -3.0292 38.2879
CTB-1 GDSC1 -3.0139 -1.4534 -3.0331 38.2143
JJN-3 GDSC1 -3.0135 -2.1319 -3.0139 38.0994
Karpas-299 GDSC1 -2.9883 -1.7068 -2.9948 37.8211
BALL-1 GDSC1 -2.8714 -1.5026 -2.8831 36.3913
MV4-11 GDSC1 -2.8296 -1.7263 -2.833 35.8186
SCC-3 GDSC1 -2.8187 -1.5099 -2.8286 35.7222
MEG-01 GDSC1 -2.7643 -1.5822 -2.7702 35.0176
U-698-M GDSC1 -2.7007 -1.381 -2.7132 34.2641
Ramos.2G6.4C10 GDSC1 -2.6789 -2.0381 -2.6789 33.9141
KMS-12-BM GDSC1 -2.6156 -1.3629 -2.6265 33.1905
CESS GDSC1 -2.5833 -1.1057 -2.6101 32.8852
Hs 445 GDSC1 -2.5804 -1.2399 -2.5969 32.7855
SKM-1 GDSC1 -2.5692 -0.2237 -2.7409 33.5736
SU-DHL-4 GDSC1 -2.4944 -1.9874 -2.4944 31.6074
L-540 GDSC1 -2.4751 -1.6112 -2.4765 31.3751
BC-1 GDSC1 -2.4675 -1.7056 -2.468 31.275
SR GDSC1 -2.4601 0.4691 -2.8179 33.299
A3/Kawakami GDSC1 -2.4302 -1.8571 -2.4302 30.8049
Jiyoye GDSC1 -2.4279 -1.4089 -2.4324 30.8046
YT GDSC1 -2.3269 -1.2399 -2.3352 29.5654
L-1236 GDSC1 -2.3251 -0.7169 -2.3812 29.8449
Farage GDSC1 -2.3095 -1.5397 -2.3103 29.3016
ROS-50 GDSC1 -2.3075 -0.4728 -2.4029 29.8725
HH [Human lymphoma] GDSC1 -2.2794 -0.0594 -2.4657 30.0927
P12-Ichikawa GDSC1 -2.2656 -1.2789 -2.2709 28.7809
Raji GDSC1 -2.2138 -1.4127 -2.2153 28.1093
BV-173 GDSC1 -2.2101 -1.1037 -2.2216 28.1262
OCI-Ly19 GDSC1 -2.1942 -1.2678 -2.1985 27.8824
VAL GDSC1 -2.1774 -0.401 -2.276 28.2724
SK-MM-2 GDSC1 -2.1741 -0.4569 -2.2616 28.1602
THP-1 GDSC1 -2.1554 -1.0943 -2.1656 27.4341
SUP-M2 GDSC1 -2.151 -1.1747 -2.1574 27.3554
NB4 GDSC1 -2.1285 -1.4172 -2.1293 27.0386
MN-60 GDSC1 -2.1178 0.1928 -2.3595 28.4475
CCRF-CEM GDSC1 -2.0973 -0.9916 -2.1116 26.7339
L-363 GDSC1 -2.039 -1.3241 -2.0401 25.9222
NKM-1 GDSC1 -1.9647 -0.4953 -2.0288 25.3957
HT GDSC1 -1.9454 -1.0166 -1.9531 24.7937
HL-60 GDSC1 -1.929 -0.9331 -1.9407 24.6137
OCI-AML-5 GDSC1 -1.9062 -0.692 -1.9382 24.4579
SIG-M5 GDSC1 -1.9003 -1.2012 -1.9017 24.1903
VL51 GDSC1 -1.8763 6.1325 -4.7238 37.2154
JVM-3 GDSC1 -1.85 -0.6926 -1.8786 23.7339
RPMI-8402 GDSC1 -1.8313 -0.9082 -1.8411 23.3806
RC-K8 GDSC1 -1.8293 -0.6435 -1.8624 23.5037
SUP-T1 GDSC1 -1.7994 -0.6825 -1.8263 23.0906
EB2 GDSC1 -1.7993 -0.9062 -1.8082 22.9751
P31/FUJ GDSC1 -1.6079 -0.2397 -1.6912 21.0645
BC-3 GDSC1 -1.5564 0.1897 -1.7465 21.1388
KCL-22 GDSC1 -1.5378 -0.4931 -1.5714 19.8638
RS4;11 GDSC1 -1.523 -0.3031 -1.5864 19.873
WSU-NHL GDSC1 -1.4906 -0.8959 -1.4925 19.0719
OPM-2 GDSC1 -1.4717 1.4156 -2.1184 23.2411
K-562 GDSC1 -1.3932 -0.3097 -1.4449 18.1743
SU-DHL-1 GDSC1 -1.3864 -1.0453 -1.3864 17.7573
KG-1 GDSC1 -1.3765 0.2921 -1.5828 19.0094
BE-13 GDSC1 -1.3686 -0.3543 -1.4108 17.8054
GR-ST GDSC1 -1.3171 1.2374 -1.8819 20.798
LP-1 GDSC1 -1.2808 2.4451 -2.3878 24.0591
EHEB GDSC1 -1.2367 -0.2351 -1.2896 16.2264
DG-75 GDSC1 -1.1327 1.002 -1.5904 17.7701
AMO1 GDSC1 -1.0259 -0.1607 -1.0759 13.5741
RL GDSC1 -0.9901 0.337 -1.1789 14.0753
LAMA-84 GDSC1 -0.9864 0.1977 -1.1282 13.7019
Karpas-422 GDSC1 -0.9314 0.3439 -1.1179 13.3291
NOMO-1 GDSC1 -0.8763 0.089 -0.9749 12.0322
HEL GDSC1 -0.8043 -0.0248 -0.8654 10.8797
GDM-1 GDSC1 -0.8025 1.3016 -1.3837 14.6282
Daudi GDSC1 -0.7973 0.5422 -1.0491 12.1293
ML-2 GDSC1 -0.7885 0.144 -0.8959 10.9978
WSU-DLCL2 GDSC1 -0.7344 2.557 -1.9137 18.2436
Mono-Mac-6 GDSC1 -0.6576 1.7587 -1.4556 14.5033
Granta-519 GDSC1 -0.6215 1.5409 -1.317 13.2889
L-428 GDSC1 -0.62 0.2478 -0.7476 9.0395
CTV-1 GDSC1 -0.5752 0.4832 -0.7907 9.1142
OCI-M1 GDSC1 -0.4703 0.3053 -0.6084 7.2536
KMS-11 GDSC1 -0.3962 0.7178 -0.7097 7.6374
ARH-77 GDSC1 -0.3194 0.443 -0.5079 5.7562
HDLM-2 GDSC1 -0.2662 2.4663 -1.4405 12.7343
ME1 GDSC1 -0.1801 4.7526 -2.5059 19.9611
JURL-MK1 GDSC1 -0.1478 1.4245 -0.8179 7.4094
OCI-AML-3 GDSC1 0.0066 1.6412 -0.7924 6.6194
PL-21 GDSC1 0.026 2.8791 -1.3951 11.2682
EM-2 GDSC1 0.1963 1.773 -0.7041 5.2613
MOLM-13 GDSC1 0.431 2.3735 -0.8235 5.4549
KM-H2 GDSC1 1.0402 2.5253 -0.5066 1.7199
JVM-2 GDSC1 1.1118 3.8395 -1.0628 5.4288
EoL-1 GDSC1 2.0318 3.5399 -0.46 0.4549
⏷ Show the Full List of 152 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-26 GDSC1 -4.5992 -3.7484 -4.5992 57.9171
KYAE-1 GDSC1 -3.6925 -2.5797 -3.6932 46.5867
HCE-4 GDSC1 -2.8636 -1.0418 -2.9125 36.5107
OACP4 C GDSC1 -2.6325 -0.5999 -2.7306 33.9271
KYSE-220 GDSC1 -1.6678 -0.2279 -1.7587 21.8626
KYSE-50 GDSC1 -1.3554 -0.0435 -1.4618 18.0652
SK-GT-4 GDSC1 -1.1407 0.1929 -1.2947 15.7097
OACM5.1 C GDSC1 -0.4575 1.8734 -1.3216 12.6062
FLO-1 GDSC1 1.0287 3.9226 -1.1567 6.3248
TE-12 GDSC1 1.0932 7.2281 -2.7228 16.8617
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 -2.222 1.8661 -3.0905 33.2204
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB69 GDSC1 -6.0546 -3.967 -6.0578 74.6388
NB(TU)1 GDSC1 -5.3007 -2.9856 -5.314 65.7594
TGW GDSC1 -5.2717 -3.22 -5.278 65.7289
KP-N-YS GDSC1 -4.973 -3.3815 -4.9744 62.4546
SK-N-MC-IXC GDSC1 -4.9582 -4.1687 -4.9582 62.4045
SiMa GDSC1 -4.9279 -2.7709 -4.9404 61.5612
CHP-212 GDSC1 -4.8754 -2.3982 -4.904 60.6692
SJNB-10 GDSC1 -4.5643 -2.3396 -4.5857 57.1834
SJNB-13 GDSC1 -4.5053 -3.5888 -4.5053 56.7427
NB1 GDSC1 -4.3957 -3.1121 -4.3963 55.3613
SK-N-FI GDSC1 -4.3917 -1.6045 -4.4669 54.8809
SJNB-6 GDSC1 -4.1808 -2.4372 -4.1886 52.6523
CHP-134 GDSC1 -4.1261 -0.5821 -4.3538 51.6937
MHH-NB-11 GDSC1 -3.9629 -1.369 -4.0403 49.9666
SJNB-5 GDSC1 -3.9436 -1.5401 -3.9998 49.737
SJNB-14 GDSC1 -3.8907 -2.6366 -3.8918 49.0626
IMR-5 GDSC1 -3.8583 -2.3713 -3.8626 48.6634
NH-12 GDSC1 -3.6976 -1.1957 -3.7804 46.8435
SK-N-DZ GDSC1 -3.5921 -1.1539 -3.6736 45.5805
SK-N-SH GDSC1 -3.5368 -1.4322 -3.5817 44.8049
LA-N-6 GDSC1 -3.5041 -0.5772 -3.6791 44.7842
Kelly GDSC1 -3.4274 -2.3831 -3.4281 43.2742
SJNB-12 GDSC1 -3.3972 0.2078 -3.7594 44.0521
GOTO GDSC1 -3.0449 -0.2577 -3.2511 39.5057
SK-N-BE(2)-M17 GDSC1 -2.9129 -1.5988 -2.9215 36.8913
SK-N-AS GDSC1 -2.9096 0.7545 -3.4005 39.1096
KP-N-YN GDSC1 -2.6083 -1.6562 -2.6103 33.0442
GI-ME-N GDSC1 -2.2465 1.7179 -3.0546 33.1925
SJNB-7 GDSC1 -1.3619 0.615 -1.6798 19.6058
SJNB-17 GDSC1 -0.1791 5.1182 -2.6877 21.0826
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 -3.0802 -0.5033 -3.2345 39.7004
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-330 GDSC1 -5.5429 -0.8675 -5.8319 64.1917
MCF-7 GDSC1 -5.5291 -3.4507 -5.5344 68.7074
EFM-19 GDSC1 -5.1089 -2.4591 -5.1423 63.1503
MDA-MB-453 GDSC1 -4.3925 -2.95 -4.3941 55.3088
HCC1187 GDSC1 -4.3749 -2.8682 -4.3771 55.0828
CAMA-1 GDSC1 -4.3688 -2.8286 -4.3715 55.0031
T-47D GDSC1 -4.3005 -1.0028 -4.4589 53.6355
HCC202 GDSC1 -4.238 0.4251 -4.7405 52.5039
DU4475 GDSC1 -4.1619 -2.9398 -4.1624 52.4472
CAL-148 GDSC1 -4.1287 -2.9129 -4.1293 52.033
OCUB-M GDSC1 -4.0444 -1.3483 -4.1298 50.9105
HCC2157 GDSC1 -3.8628 -1.0573 -3.9782 48.8207
AU565 GDSC1 -3.5985 -1.9913 -3.6086 45.4491
HCC1428 GDSC1 -3.5315 -2.5945 -3.5317 44.5722
MRK-nu-1 GDSC1 -3.5306 -2.2369 -3.5333 44.5733
BT-474 GDSC1 -3.5267 -1.463 -3.5682 44.6698
ZR-75-30 GDSC1 -3.4588 -1.7341 -3.4769 43.7446
UACC-893 GDSC1 -3.3147 -1.8771 -3.3225 41.9033
COLO 824 GDSC1 -3.2939 -1.7369 -3.3067 41.6696
HCC1419 GDSC1 -3.2281 -1.7792 -3.2374 40.8305
HCC1500 GDSC1 -3.1585 -1.8992 -3.1628 39.934
HCC1599 GDSC1 -3.1455 -1.8145 -3.1519 39.7839
MFM-223 GDSC1 -3.1099 -1.2296 -3.1523 39.5331
HCC1806 GDSC1 -3.0811 -1.0746 -3.1394 39.2572
HCC38 GDSC1 -2.8313 -0.7657 -2.9165 36.3141
MDA-MB-468 GDSC1 -2.1774 -0.0386 -2.3599 28.807
MDA-MB-157 GDSC1 -1.8867 -0.3118 -1.9788 24.6034
HCC1954 GDSC1 -1.7764 1.6289 -2.5258 27.523
MDA-MB-361 GDSC1 -1.7031 0.3663 -1.9618 23.429
HCC1395 GDSC1 -1.6184 2.4028 -2.7049 27.7396
BT-20 GDSC1 -1.5677 1.7195 -2.3487 25.2775
HCC2218 GDSC1 -1.4444 0.8635 -1.8628 21.33
Hs 578T GDSC1 -1.4228 0.4083 -1.6717 19.8799
BT-483 GDSC1 -1.4166 5.1003 -3.7904 31.9981
UACC-812 GDSC1 -1.4138 1.3932 -2.0488 22.4631
HCC1569 GDSC1 -1.2618 0.479 -1.5225 17.9608
HCC70 GDSC1 -0.9417 0.5667 -1.2121 14.0537
MDA-MB-231 GDSC1 -0.8763 2.3551 -1.9512 19.1529
CAL-120 GDSC1 -0.708 0.3654 -0.8853 10.4857
HCC1937 GDSC1 -0.6021 1.0707 -1.0774 11.3801
HDQ-P1 GDSC1 -0.5173 2.3221 -1.5966 14.9586
YMB-1-E GDSC1 -0.4315 2.3095 -1.5115 13.952
BT-549 GDSC1 -0.2498 0.9758 -0.6902 6.8321
MDA-MB-415 GDSC1 0.3476 2.1173 -0.7591 5.2091
EFM-192A GDSC1 0.5277 4.4007 -1.7526 12.226
MDA-MB-436 GDSC1 0.9724 3.294 -0.8959 4.5493
MDA-MB-175-VII GDSC1 1.0253 4.3662 -1.3718 7.9208
CAL-51 GDSC1 1.169 3.1606 -0.7152 2.849
CAL-85-1 GDSC1 1.2288 5.7017 -1.8763 10.9758
Evsa-T GDSC1 1.8837 3.385 -0.4618 0.5518
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-251MG GDSC1 -4.6638 -3.4967 -4.664 58.7132
D283 Med GDSC1 -4.196 -3.4616 -4.196 52.8778
GI-1 GDSC1 -3.4575 -2.4058 -3.4582 43.6503
GaMG GDSC1 -3.2734 -2.4529 -3.2735 41.3458
AM-38 GDSC1 -3.0118 -1.6921 -3.0192 38.1196
H4 GDSC1 -2.8621 -1.9048 -2.8633 36.2114
Daoy GDSC1 -2.7518 -1.379 -2.7661 34.9128
YKG-1 GDSC1 -2.7025 -1.7578 -2.704 34.2184
MOG-G-CCM GDSC1 -2.6954 -0.7677 -2.7702 34.5706
D-336MG GDSC1 -2.6052 -0.6961 -2.6847 33.4783
PFSK-1 GDSC1 -2.5871 -1.2125 -2.6058 32.8828
D-566MG GDSC1 -2.5855 -1.1916 -2.6056 32.8714
CAS-1 GDSC1 -2.5142 -0.8788 -2.5612 32.1477
LN-18 GDSC1 -2.4563 -1.3728 -2.4626 31.171
D-423MG GDSC1 -2.4279 -1.0848 -2.4493 30.9101
DK-MG GDSC1 -2.3795 -0.7884 -2.4294 30.485
D-542MG GDSC1 -2.3239 -0.5143 -2.4129 30.0371
SW1783 GDSC1 -2.232 -0.5332 -2.3104 28.8243
8-MG-BA GDSC1 -2.1003 -0.9752 -2.1159 26.7794
YH-13 GDSC1 -2.0705 -0.4895 -2.1438 26.7761
D-263MG GDSC1 -1.9786 0.3774 -2.2649 27.0182
D-247MG GDSC1 -1.9205 -0.0613 -2.0737 25.4265
NMC-G1 GDSC1 -1.828 -0.286 -1.9205 23.8733
MOG-G-UVW GDSC1 -1.809 0.0222 -1.974 24.1159
LN-229 GDSC1 -1.7116 -0.3285 -1.7857 22.2988
GB-1 GDSC1 -1.6788 2.5287 -2.8229 28.7347
KS-1 [Human Krukenberg tumour] GDSC1 -1.6755 0.6695 -2.0369 23.7834
SF268 GDSC1 -1.4795 -0.5691 -1.5004 19.0538
KINGS-1 GDSC1 -1.399 -0.5633 -1.4161 18.0231
Becker GDSC1 -1.3805 0.3316 -1.6001 19.1504
LN-405 GDSC1 -1.3792 0.8101 -1.7726 20.3509
SW1088 GDSC1 -1.316 -0.1115 -1.4022 17.4371
M059J GDSC1 -1.2251 0.6078 -1.5304 17.8197
U-118MG GDSC1 -1.2011 0.3195 -1.4014 16.7829
ONS-76 GDSC1 -1.1761 0.4771 -1.4295 16.8445
Onda 10 GDSC1 -1.0869 0.2859 -1.2663 15.215
SF295 GDSC1 -0.9857 -0.1529 -1.0339 13.0601
Hs 683 GDSC1 -0.9786 0.0018 -1.0624 13.2081
SK-MG-1 GDSC1 -0.9652 0.252 -1.1228 13.5476
D-502MG GDSC1 -0.9469 0.9609 -1.3796 15.2985
DBTRG-05MG GDSC1 -0.8817 1.3826 -1.5001 15.8724
D-392MG GDSC1 -0.7343 0.6052 -1.0082 11.5089
LNZTA3WT4 GDSC1 -0.7281 0.4361 -0.9338 10.9384
SNB-75 GDSC1 -0.7266 0.8503 -1.1044 12.1788
A-172 GDSC1 -0.6631 0.0041 -0.7188 9.0808
SF539 GDSC1 -0.5518 0.9304 -0.9628 10.2793
42-MG-BA GDSC1 -0.473 6.1352 -3.4486 26.3712
SF126 GDSC1 -0.3303 1.9031 -1.2191 11.2816
T98G GDSC1 -0.2843 0.4824 -0.4899 5.4528
KNS-81-FD GDSC1 0.0974 1.4733 -0.6334 5.0409
KALS-1 GDSC1 0.1137 1.8956 -0.8311 6.541
KNS-42 GDSC1 0.2983 1.9904 -0.7334 5.1623
U-87MG ATCC GDSC1 0.3362 2.0334 -0.7262 4.9886
Onda 11 GDSC1 1.2894 3.2203 -0.6744 2.3603
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 -3.4826 -1.2947 -3.5392 44.1816
TGBC24TKB GDSC1 -2.3459 -1.1253 -2.361 29.8463
TGBC1TKB GDSC1 -1.9962 -0.5536 -2.0533 25.744
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-319 GDSC1 -3.9452 -2.3107 -3.9522 49.7447
RL95-2 GDSC1 -3.725 -1.9477 -3.7403 47.0328
EN GDSC1 -3.2387 -0.0678 -3.5102 42.0189
MFE-296 GDSC1 -2.8605 1.5746 -3.6473 39.6424
ESS-1 GDSC1 -2.3436 -1.3408 -2.3485 29.7535
AN3-CA GDSC1 -2.3287 -0.1591 -2.4944 30.5748
MFE-280 GDSC1 -1.9516 -0.2627 -2.0597 25.5181
KLE GDSC1 -1.6564 1.8646 -2.5033 26.7301
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VMRC-RCZ GDSC1 -3.4002 -2.2784 -3.4015 42.9376
KTCTL-21 GDSC1 -3.3583 -1.611 -3.3804 42.5152
769-P GDSC1 -2.9152 -1.8537 -2.9174 36.8815
786-O GDSC1 -2.7934 -1.0636 -2.8356 35.5991
LB1047-RCC GDSC1 -2.6308 -1.4939 -2.6367 33.3494
KTCTL-140 GDSC1 -2.5517 -0.9273 -2.5951 32.5933
KTCTL-13 GDSC1 -2.2 0.0924 -2.4202 29.3251
RXF 393L GDSC1 -2.1292 -0.4512 -2.2142 27.5842
CAL-54 GDSC1 -1.8431 -0.7822 -1.8625 23.5885
KTCTL-195 GDSC1 -1.8103 0.4863 -2.1181 25.0854
SW13 GDSC1 -1.7469 -0.4401 -1.8036 22.6267
SW156 GDSC1 -1.7315 0.5861 -2.0674 24.3018
KTCTL-26A GDSC1 -1.6608 0.2734 -1.886 22.6761
LB2241-RCC GDSC1 -1.5033 -0.1271 -1.6026 19.8643
BFTC-909 GDSC1 -1.4229 0.5944 -1.7377 20.3398
TK-10 GDSC1 -1.3455 0.5589 -1.6415 19.2485
KMRC-20 GDSC1 -1.315 0.8721 -1.7289 19.7036
KTCTL-1M GDSC1 -1.2435 0.4778 -1.5023 17.7201
RCC10RGB GDSC1 -1.2285 0.8124 -1.6135 18.4294
VMRC-RCW GDSC1 -1.1806 -0.054 -1.2685 15.7577
HA7-RCC GDSC1 -1.1538 0.1924 -1.3087 15.8798
BB65-RCC GDSC1 -1.1058 0.1647 -1.2479 15.1926
A-704 GDSC1 -1.0815 1.1282 -1.5909 17.516
LB996-RCC GDSC1 -1.0722 0.3463 -1.2709 15.1671
NCC021 GDSC1 -1.0663 0.6239 -1.367 15.8168
Caki-1 GDSC1 -0.857 0.6146 -1.1412 13.1037
SN12C GDSC1 -0.5279 0.2065 -0.6337 7.7397
ACHN GDSC1 -0.4915 0.8328 -0.8577 9.2028
A-498 GDSC1 -0.4168 1.3618 -1.0348 10.2188
OS-RC-2 GDSC1 -0.0177 1.3789 -0.6818 5.8379
KMRC-1 GDSC1 0.4114 1.6387 -0.4796 2.8724
UO-31 GDSC1 0.737 3.7308 -1.2661 7.9444
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCT 116 GDSC1 -4.5857 -3.0769 -4.5873 57.697
LS411N GDSC1 -4.3851 -3.1401 -4.3856 55.2322
SNU-C1 GDSC1 -4.3702 -1.8264 -4.4207 54.7401
COLO 320HSR GDSC1 -3.8006 -2.5656 -3.8019 47.9391
NCI-H747 GDSC1 -3.7966 -2.5381 -3.798 47.8891
HT115 GDSC1 -3.6689 -2.5601 -3.6695 46.2913
SW620 GDSC1 -3.5547 -3.0316 -3.5547 44.8611
NCI-H716 GDSC1 -3.534 -0.774 -3.6728 45.0398
SNU-61 GDSC1 -3.4106 -0.3428 -3.6294 43.8251
KM12 GDSC1 -3.2861 -1.511 -3.3122 41.6372
CaR-1 GDSC1 -3.217 -1.6251 -3.2331 40.7289
SW1417 GDSC1 -3.0852 -1.5842 -3.0993 39.0742
SW626 GDSC1 -3.0286 -1.6096 -3.0398 38.3518
LS513 GDSC1 -2.9796 -1.4826 -2.9957 37.7684
COLO205 GDSC1 -2.9698 -2.2223 -2.9699 37.5512
HT-55 GDSC1 -2.9536 -1.9618 -2.9548 37.3555
CL-11 GDSC1 -2.8906 -1.1008 -2.9343 36.8172
LS123 GDSC1 -2.8753 -1.9616 -2.8761 36.3742
HT-29 GDSC1 -2.8148 -1.5491 -2.823 35.6632
RCM-1 [Human ESC] GDSC1 -2.8051 -1.391 -2.8206 35.5865
HCC2998 GDSC1 -2.6503 -1.1723 -2.6747 33.7068
LS1034 GDSC1 -2.5342 -1.2192 -2.5504 32.2059
SNU-1040 GDSC1 -2.5259 0.1533 -2.7931 33.5875
SNU-407 GDSC1 -2.4769 0.3525 -2.7993 33.3043
LS180 GDSC1 -2.4302 -0.8486 -2.4757 31.0903
CCK-81 GDSC1 -2.3531 -0.9231 -2.3855 30.0455
SW1116 GDSC1 -2.2877 0.2793 -2.5707 30.7873
COLO 678 GDSC1 -2.2002 0.0094 -2.3976 29.1838
SW1463 GDSC1 -2.167 -1.369 -2.1687 27.5256
SNU-C5 GDSC1 -2.1103 0.3715 -2.4062 28.6978
LoVo GDSC1 -2.0372 -0.7485 -2.0705 26.1034
SW48 GDSC1 -1.8436 -0.1258 -1.9737 24.3155
SNU-81 GDSC1 -1.8433 0.5093 -2.1617 25.562
RKO GDSC1 -1.8017 0.7163 -2.1897 25.5118
MDST8 GDSC1 -1.7881 -0.7717 -1.8057 22.8898
GP5d GDSC1 -1.5138 -0.2594 -1.585 19.8085
SNU-C2B GDSC1 -1.4009 0.5353 -1.6926 19.9058
SNU-175 GDSC1 -1.2384 -0.1352 -1.3123 16.3861
SW948 GDSC1 -1.0977 2.4867 -2.2279 22.1118
T84 GDSC1 -0.6127 1.7496 -1.4082 13.9432
SW837 GDSC1 -0.2887 4.5161 -2.4812 20.2349
HCT 15 GDSC1 1.3886 3.631 -0.8003 2.9998
CW-2 GDSC1 2.3065 4.1241 -0.5653 0.6427
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 -1.6182 1.2231 -2.191 24.5096
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-1 GDSC1 -4.9071 -3.4632 -4.9078 61.6933
SNU-475 GDSC1 -4.3074 -1.5906 -4.3791 53.9426
JHH-4 GDSC1 -3.2604 -1.6 -3.2795 41.2846
HLE GDSC1 -2.9192 -1.357 -2.9412 37.0491
SNU-423 GDSC1 -2.7801 -0.1024 -3.001 36.4073
JHH-7 GDSC1 -2.3702 -0.3851 -2.4883 30.7947
SNU-387 GDSC1 -2.0446 1.9313 -2.9332 31.3721
JHH-6 GDSC1 -1.9399 0.6073 -2.3 27.0212
Hep-G2/C3A GDSC1 -1.766 -0.8536 -1.7767 22.5699
HuH-1 GDSC1 -1.7555 -0.3343 -1.832 22.8631
Hep 3B2.1-7 GDSC1 -1.4641 -0.1559 -1.5533 19.3073
JHH-2 GDSC1 -1.2408 -0.0269 -1.341 16.5922
SNU-449 GDSC1 -1.1917 1.564 -1.8953 20.2599
SK-HEP-1 GDSC1 -1.1444 1.3403 -1.748 18.9687
Huh-7 GDSC1 0.4642 5.3118 -2.2554 15.9617
SNU-398 GDSC1 0.9288 3.2444 -0.9006 4.6893
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 171 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COR-L303 GDSC1 -5.7961 -4.0712 -5.797 72.2847
NCI-H720 GDSC1 -5.4011 -1.9767 -5.4936 65.0922
COR-L88 GDSC1 -4.968 -2.7152 -4.9835 61.9546
NCI-H847 GDSC1 -4.8489 -3.6563 -4.8491 61.0185
HCC78 GDSC1 -4.8184 -2.8146 -4.8273 60.3576
NCI-H1581 GDSC1 -4.7784 -3.7672 -4.7784 60.1522
LK-2 GDSC1 -4.6573 -3.6785 -4.6574 58.6414
NCI-H1105 GDSC1 -4.3167 -2.2741 -4.3338 54.2672
Lu-135 GDSC1 -4.1759 -1.4878 -4.2518 52.4329
SBC-5 GDSC1 -4.0562 -3.2603 -4.0562 51.1306
NCI-H1436 GDSC1 -4.0561 -2.0804 -4.0749 51.1031
NCI-H810 GDSC1 -3.9763 -2.6341 -3.978 50.1306
PC-14 GDSC1 -3.9696 -2.4949 -3.973 50.0469
NCI-H187 GDSC1 -3.9614 -3.1257 -3.9614 49.9452
EBC-1 GDSC1 -3.955 -1.6512 -4.0006 49.8706
NCI-H146 GDSC1 -3.9337 -2.3419 -3.9397 49.6015
LB647-SCLC GDSC1 -3.9005 -2.1419 -3.9122 49.1951
NCI-H510A GDSC1 -3.8873 -1.8863 -3.9115 49.0424
IST-SL2 GDSC1 -3.8494 -1.5327 -3.9012 48.6098
NCI-H290 GDSC1 -3.7869 -2.473 -3.7889 47.7699
NCI-H2196 GDSC1 -3.7751 -1.1333 -3.8722 47.7821
NCI-H1694 GDSC1 -3.6934 -2.2682 -3.6976 46.6103
COR-L321 GDSC1 -3.6305 -2.8463 -3.6305 45.8089
PaCa-3 GDSC1 -3.4947 -1.729 -3.5143 44.1963
NCI-H64 GDSC1 -3.4467 -3.0463 -3.4467 43.5117
NCI-H2347 GDSC1 -3.4419 -0.8763 -3.5552 43.8768
SBC-3 GDSC1 -3.3449 -1.4118 -3.3819 42.4147
Lu-139 GDSC1 -3.3212 0.1615 -3.6632 43.165
NCI-H526 GDSC1 -3.2559 -1.6605 -3.2714 41.2099
NCI-H647 GDSC1 -3.1842 -1.9584 -3.1877 40.2505
NCI-H1623 GDSC1 -3.1825 -1.6283 -3.1973 40.2913
NCI-H2135 GDSC1 -3.1721 -0.75 -3.2863 40.6339
LC-2/ad GDSC1 -3.1588 -1.3949 -3.1883 40.0732
COR-L311 GDSC1 -3.1339 -1.9339 -3.1372 39.6217
EPLC-272H GDSC1 -3.0825 -0.4445 -3.2494 39.783
NCI-H2803 GDSC1 -3.0771 -1.3347 -3.1079 39.0652
HCC33 GDSC1 -2.9819 -1.929 -2.9837 37.7124
Calu-6 GDSC1 -2.9711 -0.6484 -3.0876 38.1973
NCI-H1944 GDSC1 -2.9594 -0.6399 -3.0765 38.058
Lu-99A GDSC1 -2.9381 -0.5286 -3.075 37.8968
NCI-H1651 GDSC1 -2.8891 -1.6136 -2.8966 36.5869
NCI-H1770 GDSC1 -2.8362 -2.1377 -2.8363 35.8811
COR-L23 GDSC1 -2.7967 -1.1434 -2.8308 35.5923
NCI-H1666 GDSC1 -2.7635 -0.2816 -2.939 35.9706
NCI-H226 GDSC1 -2.756 -2.0104 -2.7561 34.8784
HOP-62 GDSC1 -2.7439 -0.31 -2.911 35.6868
COLO 668 GDSC1 -2.7085 -0.175 -2.9046 35.4118
HCC827 GDSC1 -2.7058 -0.9434 -2.7568 34.5596
Calu-3 GDSC1 -2.6796 0.3743 -3.0268 35.8448
NCI-H1876 GDSC1 -2.6572 -1.0869 -2.6895 33.8413
NCI-H520 GDSC1 -2.6233 -0.6258 -2.7162 33.7826
NCI-H522 GDSC1 -2.6206 -1.0888 -2.6508 33.3719
NCI-H841 GDSC1 -2.5961 -0.3133 -2.7494 33.7989
NCI-H2444 GDSC1 -2.5852 0.0793 -2.8368 34.2185
NCI-H1155 GDSC1 -2.577 -1.9115 -2.5771 32.6412
A-427 GDSC1 -2.5537 -0.5381 -2.6569 32.9805
NCI-H209 GDSC1 -2.5031 1.2707 -3.149 35.2561
NCI-H2373 GDSC1 -2.4814 -1.3208 -2.4903 31.5007
UMC-11 GDSC1 -2.4764 -1.2221 -2.4903 31.4699
NCI-H2170 GDSC1 -2.4498 -1.0192 -2.4779 31.2259
EMC-BAC-2 GDSC1 -2.4433 -1.3462 -2.4503 31.0126
NCI-H1648 GDSC1 -2.3854 -1.3607 -2.3906 30.278
NCI-H2722 GDSC1 -2.3849 -0.4587 -2.4895 30.8933
NCI-H1304 GDSC1 -2.3798 -1.1596 -2.394 30.2642
SHP-77 GDSC1 -2.374 -0.4457 -2.4801 30.7671
HCC15 GDSC1 -2.3714 -0.0874 -2.5589 31.2354
Lu-65 GDSC1 -2.3622 0.1351 -2.6093 31.4809
ChaGo-K-1 GDSC1 -2.3532 -0.9276 -2.3852 30.0436
NCI-H3122 GDSC1 -2.3456 0.4718 -2.6944 31.8771
NCI-H1734 GDSC1 -2.3442 -0.4721 -2.4428 30.35
NCI-H2081 GDSC1 -2.337 -0.9866 -2.3625 29.8004
NCI-H727 GDSC1 -2.3255 0.2405 -2.6002 31.1979
NCI-H322M GDSC1 -2.3201 -0.6155 -2.3913 29.8773
Lu-134-A GDSC1 -2.3192 -0.5543 -2.4007 29.9306
NCI-H23 GDSC1 -2.3171 -1.1293 -2.3309 29.4779
NCI-H2171 GDSC1 -2.296 -1.4829 -2.2973 29.136
NCI-H441 GDSC1 -2.2625 0.5158 -2.6186 30.9177
BEN GDSC1 -2.2604 -1.7273 -2.2604 28.683
NCI-H661 GDSC1 -2.2439 -0.7994 -2.2838 28.7285
NCI-H2141 GDSC1 -2.2361 -1.077 -2.2502 28.468
NCI-H2818 GDSC1 -2.1933 -0.8632 -2.2231 28.0324
NCI-H1781 GDSC1 -2.1765 0.3739 -2.479 29.5484
LCLC-97TM1 GDSC1 -2.165 0.0239 -2.363 28.7527
NCI-H2795 GDSC1 -2.1551 -0.8696 -2.1822 27.5377
NCI-H1341 GDSC1 -2.1445 -1.294 -2.1472 27.2507
NCI-H460 GDSC1 -2.1055 -1.1077 -2.1136 26.7971
NCI-H2405 GDSC1 -2.0442 -0.1628 -2.1834 26.8747
DMS 273 GDSC1 -2.0248 0.6541 -2.4081 28.2046
NCI-H2029 GDSC1 -1.9967 -0.9131 -2.0125 25.4857
CPC-N GDSC1 -1.9762 -1.0762 -1.9822 25.1683
NCI-H1792 GDSC1 -1.9717 -0.5247 -2.0315 25.4555
NCI-H2804 GDSC1 -1.9527 -0.3739 -2.0379 25.3823
NCI-H838 GDSC1 -1.9382 -0.2344 -2.0514 25.3842
NCI-H69 GDSC1 -1.9286 -0.9544 -1.9391 24.6015
LCLC-103H GDSC1 -1.9258 -0.9262 -1.9378 24.5758
Lu-165 GDSC1 -1.8807 -0.5692 -1.9272 24.2326
NCI-H1836 GDSC1 -1.8683 -0.3061 -1.96 24.3716
COR-L105 GDSC1 -1.7849 0.3464 -2.0443 24.4472
NCI-H211 GDSC1 -1.7802 -0.8844 -1.7896 22.7395
NCI-H596 GDSC1 -1.698 1.6253 -2.4428 26.5773
NCI-H196 GDSC1 -1.6802 -0.9836 -1.683 21.4474
IST-SL1 GDSC1 -1.6645 -0.2284 -1.7551 21.8196
NCI-H1869 GDSC1 -1.6341 -0.1634 -1.7366 21.5182
A-549 GDSC1 -1.6334 -0.8882 -1.6383 20.8763
NCI-H1975 GDSC1 -1.6238 0.5593 -1.9417 22.8493
NCI-H2810 GDSC1 -1.6216 -0.3615 -1.6822 21.0869
NCI-H650 GDSC1 -1.5805 0.634 -1.9218 22.4742
ABC-1 GDSC1 -1.5625 1.0705 -2.0702 23.3943
CAL-12T GDSC1 -1.5311 -0.1043 -1.6383 20.2635
SBC-1 GDSC1 -1.5304 -0.8909 -1.5331 19.5745
NCI-H1435 GDSC1 -1.5279 -0.5276 -1.5564 19.7071
NCI-H446 GDSC1 -1.5225 -0.606 -1.542 19.5822
NCI-H1915 GDSC1 -1.522 -0.4303 -1.5635 19.7175
NCI-H2030 GDSC1 -1.4944 -0.1903 -1.5785 19.6522
NCI-H345 GDSC1 -1.4871 -0.3548 -1.5383 19.3445
NCI-H2461 GDSC1 -1.4832 -0.6588 -1.4961 19.0492
RERF-LC-MS GDSC1 -1.4484 0.5319 -1.7426 20.5126
NCI-H1355 GDSC1 -1.4444 1.1738 -1.9881 22.2026
NCI-H2228 GDSC1 -1.4177 0.5493 -1.7158 20.1589
NCI-H1703 GDSC1 -1.4063 -0.2471 -1.4709 18.4223
NCI-H2731 GDSC1 -1.3907 -0.1247 -1.4805 18.3943
HCC44 GDSC1 -1.3893 0.1691 -1.5581 18.9106
NCI-H358 GDSC1 -1.3396 0.8814 -1.7587 20.0435
NCI-H2110 GDSC1 -1.3185 0.8958 -1.7421 19.8159
SW1573 GDSC1 -1.309 0.0199 -1.4278 17.5691
IA-LM GDSC1 -1.3088 2.0274 -2.2229 23.1129
NCI-H2595 GDSC1 -1.2961 0.0254 -1.4152 17.4104
LXF 289 GDSC1 -1.2844 0.2354 -1.4644 17.6798
NCI-H1688 GDSC1 -1.2796 -0.3099 -1.3224 16.6963
NCI-H2172 GDSC1 -1.2423 0.2848 -1.4346 17.2404
NCI-H1048 GDSC1 -1.2133 0.0518 -1.3321 16.3743
NCI-H2291 GDSC1 -1.1775 5.9362 -3.9788 31.6393
NCI-H2342 GDSC1 -1.1761 0.6132 -1.4801 17.2028
NCI-H2087 GDSC1 -1.1741 0.6837 -1.5051 17.3702
NCI-H1573 GDSC1 -1.1727 -0.0573 -1.2591 15.6499
DMS 53 GDSC1 -1.1644 0.7818 -1.5334 17.5221
NCI-H2066 GDSC1 -1.1434 0.9388 -1.5752 17.7152
NCI-H524 GDSC1 -1.1143 0.0032 -1.2108 14.9884
LOU-NH91 GDSC1 -1.0554 0.0754 -1.1664 14.3513
NCI-H1563 GDSC1 -1.0351 1.1741 -1.5629 17.0807
SK-MES-1 GDSC1 -0.9172 0.0916 -1.0204 12.5738
KNS-62 GDSC1 -0.9145 1.0167 -1.3703 15.0694
NCI-H2085 GDSC1 -0.8085 1.0784 -1.2889 13.9483
SW1271 GDSC1 -0.6578 0.8916 -1.0522 11.4552
NCI-H2122 GDSC1 -0.6573 1.5621 -1.3617 13.7897
RERF-LC-Sq1 GDSC1 -0.6317 8.2275 -4.6298 31.6928
HARA [Human squamous cell lung carcinoma] GDSC1 -0.5934 0.8366 -0.9622 10.4723
NCI-H82 GDSC1 -0.5805 0.2068 -0.6906 8.425
NCI-H1092 GDSC1 -0.5596 0.1714 -0.6559 8.0681
NCI-H2369 GDSC1 -0.5402 0.3946 -0.7179 8.4062
NCI-H2869 GDSC1 -0.5111 3.9467 -2.3932 20.5804
NCI-H1650 GDSC1 -0.4799 0.969 -0.9091 9.5376
NCI-H2009 GDSC1 -0.399 1.0786 -0.8818 8.9633
NCI-H292 GDSC1 -0.3316 0.5647 -0.575 6.3174
NCI-H513 GDSC1 -0.3094 1.7173 -1.1084 10.3352
NCI-H1437 GDSC1 -0.3019 1.5078 -0.9985 9.4482
NCI-H1793 GDSC1 -0.2924 1.372 -0.9232 8.8226
NCI-H1299 GDSC1 -0.2009 1.1295 -0.7199 6.8576
EMC-BAC-1 GDSC1 -0.1995 5.7849 -3.0381 23.1785
DMS 114 GDSC1 -0.1675 1.4967 -0.8712 7.9061
SK-LU-1 GDSC1 -0.1369 1.385 -0.7886 7.137
NCI-H2023 GDSC1 -0.132 2.3847 -1.2823 10.9853
NCI-H1755 GDSC1 0.0026 1.0319 -0.4912 4.2598
NCI-H1838 GDSC1 0.0134 4.3506 -2.1413 16.8039
EKVX GDSC1 0.0458 2.9997 -1.4389 11.5323
NCI-H1993 GDSC1 0.1189 2.3211 -1.0394 8.1617
Ms-1 GDSC1 0.1827 1.8067 -0.7315 5.5222
RERF-LC-KJ GDSC1 0.3461 2.9688 -1.1819 8.5055
NCI-H2591 GDSC1 0.513 4.7839 -1.9543 13.7245
NCI-H3255 GDSC1 1.3031 3.3075 -0.7051 2.5335
NCI-H1568 GDSC1 1.3582 3.513 -0.7651 2.8246
⏷ Show the Full List of 171 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 -1.7045 -0.1374 -1.8193 22.4789
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-4 GDSC1 -4.7079 -3.8147 -4.708 59.2754
KYSE-520 GDSC1 -3.3719 0.7161 -3.8893 44.144
OE19 GDSC1 -3.2278 -2.173 -3.2289 40.7819
TE-10 GDSC1 -3.0068 -1.0654 -3.0616 38.3199
KYSE-410 GDSC1 -2.8757 -1.1181 -2.9167 36.6165
T.T GDSC1 -2.8446 -0.9878 -2.8988 36.3046
KYSE-450 GDSC1 -2.5237 -1.6867 -2.5246 31.9795
OE21 GDSC1 -2.1811 -1.056 -2.1945 27.7755
KYSE-70 GDSC1 -2.1705 -0.9285 -2.1929 27.6997
TE-1 GDSC1 -2.11 1.9739 -3.0193 32.1995
KYSE-150 GDSC1 -2.0463 -0.6975 -2.0863 26.2601
KYSE-180 GDSC1 -1.8083 0.0184 -1.9723 24.101
COLO 680N GDSC1 -1.8006 -0.025 -1.9524 23.9236
TE-9 GDSC1 -1.7065 -0.1161 -1.8266 22.5394
OE33 GDSC1 -1.5067 0.1281 -1.674 20.3643
KYSE-270 GDSC1 -1.3627 5.9424 -4.1519 33.1032
TE-15 GDSC1 -1.0096 4.6634 -3.199 27.4381
TE-8 GDSC1 -0.781 6.2251 -3.7643 29.0651
EC-GI-10 GDSC1 -0.541 0.5526 -0.7841 8.8927
TE-11 GDSC1 0.1132 1.8753 -0.8214 6.4664
KYSE-140 GDSC1 0.1797 2.2897 -0.9747 7.4428
TE-5 GDSC1 0.7414 4.7331 -1.7551 11.5607
KYSE-510 GDSC1 5.6274 19.5094 -5.53 18.5909
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FU-OV-1 GDSC1 -3.7668 -0.4031 -4.0032 47.8531
A2780 GDSC1 -3.593 -1.564 -3.6287 45.4649
TOV-112D GDSC1 -3.5214 -2.2657 -3.5237 44.4567
IGROV-1 GDSC1 -3.518 -0.5228 -3.7058 44.9767
OVCAR-3 GDSC1 -3.2388 -2.0557 -3.2413 40.9274
OVCAR-8 GDSC1 -2.8527 -1.2191 -2.8827 36.2657
OV-90 GDSC1 -2.7653 -1.1804 -2.7945 35.1717
Kuramochi GDSC1 -2.6158 -1.3635 -2.6266 33.193
OVISE GDSC1 -2.2946 -1.3826 -2.2976 29.129
EFO-27 GDSC1 -2.1839 0.1677 -2.4242 29.2523
ES-2 GDSC1 -1.9606 -1.1417 -1.9641 24.9572
TYK-nu GDSC1 -1.9012 -0.8175 -1.9203 24.3128
TOV-21G GDSC1 -1.8575 0.9788 -2.3477 26.8574
RMG-I GDSC1 -1.6174 -0.246 -1.7002 21.18
SK-OV-3 GDSC1 -1.6074 -0.6039 -1.6319 20.6754
DOV13 GDSC1 -1.1573 0.8874 -1.5687 17.7395
OVTOKO GDSC1 -1.1259 0.5884 -1.4169 16.4873
JHOS-2 GDSC1 -0.9788 2.1312 -1.944 19.578
OVKATE GDSC1 -0.9688 2.4617 -2.0911 20.5665
OAW42 GDSC1 -0.9675 0.7617 -1.3175 14.9488
OVCAR-5 GDSC1 -0.9209 0.6421 -1.2199 14.0019
EFO-21 GDSC1 -0.7689 2.1038 -1.7277 17.0396
OVCAR-4 GDSC1 -0.7542 0.9498 -1.1764 12.8475
OC 314 GDSC1 -0.7131 2.5034 -1.8676 17.8155
OVK18 GDSC1 -0.5178 5.2362 -3.04 24.4701
JHOS-4 GDSC1 -0.455 6.2229 -3.4767 26.4326
Caov-3 GDSC1 0.3061 2.1685 -0.8156 5.7795
OV56 GDSC1 0.3701 1.5419 -0.4613 2.8464
OAW28 GDSC1 0.7589 3.6923 -1.2317 7.621
Caov-4 GDSC1 2.8038 4.9591 -0.6744 0.7073
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AsPC-1 GDSC1 -3.238 -0.5436 -3.3972 41.609
Panc 10.05 GDSC1 -3.139 -0.8577 -3.2324 40.1387
MZ-PC-1 GDSC1 -2.9089 1.1055 -3.5229 39.5565
HuP-T4 GDSC1 -2.4502 -0.9611 -2.484 31.2671
BxPC-3 GDSC1 -2.2883 -0.6809 -2.347 29.402
SUIT-2 GDSC1 -2.2217 -0.4977 -2.3056 28.7309
Panc 03.27 GDSC1 -2.1839 -0.8303 -2.2166 27.933
KP-4 GDSC1 -1.9577 -0.8122 -1.9801 25.0402
PaTu 8902 GDSC1 -1.83 0.0882 -2.0152 24.512
QGP-1 GDSC1 -1.7817 1.4368 -2.4508 27.0873
SW1990 GDSC1 -1.4538 1.1124 -1.9727 22.1457
PSN1 GDSC1 -1.445 -0.1935 -1.5241 19.002
Panc 02.03 GDSC1 -1.3815 0.6153 -1.701 19.8597
HuP-T3 GDSC1 -1.3712 0.6827 -1.7151 19.9036
MIA PaCa-2 GDSC1 -1.2917 0.4801 -1.5551 18.3515
Hs 766T GDSC1 -1.2245 0.4115 -1.4583 17.3084
Capan-1 GDSC1 -1.2119 0.4046 -1.4423 17.1277
PL4 GDSC1 -1.0807 0.854 -1.4744 16.6652
CFPAC-1 GDSC1 -1.0608 0.1306 -1.1885 14.5323
YAPC GDSC1 -0.8226 1.439 -1.4669 15.3444
DAN-G GDSC1 -0.8051 0.097 -0.8997 11.1164
HPAF-II GDSC1 -0.6777 2.9359 -2.0456 18.9342
KP-3 GDSC1 -0.5779 1.3935 -1.2047 12.2364
Panc 08.13 GDSC1 -0.5357 1.0563 -1.0048 10.5219
KP-1N GDSC1 -0.3112 2.3644 -1.4299 12.8334
SU.86.86 GDSC1 -0.209 1.0759 -0.701 6.7437
PaTu 8988t GDSC1 -0.0249 1.5141 -0.7556 6.446
HPAC GDSC1 0.0178 2.3553 -1.14 9.3125
Capan-2 GDSC1 0.1082 4.3144 -2.0445 15.7782
Panc 04.03 GDSC1 1.1064 3.2246 -0.7807 3.4248
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-Mes1 GDSC1 -1.736 -0.7845 -1.7503 22.2173
NCI-H28 GDSC1 -1.6266 -0.5136 -1.6634 20.9943
MSTO-211H GDSC1 -1.4768 -0.3994 -1.5199 19.163
MPP 89 GDSC1 -1.3548 -0.0769 -1.4528 18.0005
NCI-H2052 GDSC1 -1.1577 0.2819 -1.3418 16.1298
NCI-H2452 GDSC1 -0.4273 0.8605 -0.8066 8.5168
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1 -6.3237 -3.8959 -6.3306 76.7003
22Rv1 GDSC1 -4.2435 -2.5744 -4.249 53.4355
PC-3 GDSC1 -2.9367 0.5816 -3.3725 39.1977
LNCaP clone FGC GDSC1 -2.8055 -0.3001 -2.9804 36.4777
DU145 GDSC1 -1.6422 0.8876 -2.0829 23.9126
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 -2.2182 0.2594 -2.4889 29.8624
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-431 GDSC1 -4.2432 -2.3192 -4.2564 53.3955
LB373-MEL-D GDSC1 -3.332 -1.6073 -3.3533 42.1847
IGR-1 GDSC1 -3.2887 0.3619 -3.6867 42.9641
SK-MEL-5 GDSC1 -3.1386 -1.0741 -3.2007 39.986
CP66-MEL GDSC1 -3.1044 -1.3017 -3.1394 39.4265
Hs 938.T GDSC1 -3.0272 -1.2274 -3.0654 38.4845
COLO 800 GDSC1 -2.9409 2.1918 -3.9792 41.1795
G-361 GDSC1 -2.8566 -1.5167 -2.8672 36.2001
MeWo GDSC1 -2.7588 -0.6053 -2.8661 35.5414
RPMI-7951 GDSC1 -2.725 -1.3487 -2.7401 34.5837
CP50-MEL-B GDSC1 -2.3853 2.5601 -3.5565 36.2418
MMAc-SF GDSC1 -2.3013 -0.6521 -2.3653 29.5977
WM278 GDSC1 -2.147 -0.5268 -2.2199 27.729
SK-MEL-24 GDSC1 -2.0124 -0.527 -2.0749 25.9812
WM115 GDSC1 -2.0086 -1.1194 -2.0137 25.5673
SK-MEL-30 GDSC1 -1.9518 1.5122 -2.6604 29.318
HT-144 GDSC1 -1.8979 0.236 -2.1327 25.6836
COLO 829 GDSC1 -1.8836 2.9692 -3.2295 31.9423
A-375 GDSC1 -1.7603 1.3137 -2.3776 26.5055
UACC-257 GDSC1 -1.7379 -0.5666 -1.7749 22.3867
SK-MEL-3 GDSC1 -1.6936 -0.4052 -1.7522 21.9726
Mel JuSo GDSC1 -1.6836 0.1109 -1.862 22.6441
GAK GDSC1 -1.6804 -0.4287 -1.7339 21.7747
MZ-MEL-2 GDSC1 -1.6722 0.0178 -1.8236 22.3198
IST-MEL1 GDSC1 -1.6153 -0.6002 -1.6406 20.7797
M14 GDSC1 -1.4851 -0.1212 -1.5842 19.6354
A-388 GDSC1 -1.4763 -0.5872 -1.4952 19.0013
LB2518-MEL GDSC1 -1.4604 0.2917 -1.6738 20.1025
IGR-37 GDSC1 -1.3276 -0.0137 -1.4391 17.7519
Mel Ho GDSC1 -1.2815 0.0746 -1.4129 17.3117
DJM-1 GDSC1 -1.2782 1.4602 -1.9379 20.9949
MZ-MEL-7 GDSC1 -1.2548 -0.4628 -1.2744 16.2372
WM793 GDSC1 -1.2272 -0.3093 -1.2661 16.0169
LOX-IMVI GDSC1 -1.1841 0.1804 -1.338 16.2498
IPC-298 GDSC1 -1.0241 0.0278 -1.119 13.8509
HMV-II GDSC1 -1.0168 0.5046 -1.2685 14.8529
COLO 679 GDSC1 -0.7522 3.6303 -2.455 22.0169
A101D GDSC1 -0.6533 -0.0769 -0.6889 8.8243
SK-MEL-2 GDSC1 -0.6369 -0.1092 -0.6646 8.5665
COLO 783 GDSC1 -0.4962 1.0863 -0.9801 10.1528
CHL-1 GDSC1 -0.4643 5.8403 -3.294 25.5774
SK-MEL-28 GDSC1 -0.4191 1.7782 -1.2393 11.809
SH-4 GDSC1 -0.4115 2.5151 -1.5948 14.5014
G-mel GDSC1 -0.1104 3.381 -1.7612 14.5515
SK-MEL-1 GDSC1 -0.099 5.169 -2.645 20.5113
A2058 GDSC1 -0.0202 2.7329 -1.3607 11.1725
WT2-iPS GDSC1 0.1378 3.5809 -1.6536 12.8297
WM1552C GDSC1 0.3301 3.5697 -1.4934 10.952
UACC-62 GDSC1 0.5062 2.1756 -0.6733 4.0843
451Lu GDSC1 0.5587 3.61 -1.3376 9.0247
RVH-421 GDSC1 2.2758 9.1365 -2.8115 14.0642
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 -4.1216 -3.1017 -4.1217 51.9473
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 633.T GDSC1 -5.151 -3.7522 -5.1514 64.7223
SK-LMS-1 GDSC1 -4.0632 -2.3921 -4.0701 51.2047
EW-8 GDSC1 -3.9594 -2.6296 -3.961 49.9198
SW872 GDSC1 -3.5375 -1.9098 -3.5493 44.6972
Rh41 GDSC1 -3.4984 -2.5555 -3.4987 44.1595
SK-UT-1 GDSC1 -3.3711 -0.7398 -3.503 43.0937
KYM-1 GDSC1 -3.1934 -1.838 -3.2 40.3834
Rh30 GDSC1 -3.1813 -2.3818 -3.1814 40.195
SW982 GDSC1 -2.8387 -1.4572 -2.8516 35.9902
VA-ES-BJ GDSC1 -2.6713 -0.111 -2.8801 35.0282
MES-SA GDSC1 -2.3916 -0.9779 -2.4206 30.5048
G-402 GDSC1 -2.3536 -0.5651 -2.4359 30.3651
G-401 GDSC1 -2.1736 -0.2875 -2.2957 28.3752
GCT GDSC1 -2.1359 0.02 -2.3302 28.3683
TE 441.T GDSC1 -2.0715 -0.2521 -2.1924 27.0961
RD GDSC1 -1.9686 -0.8183 -1.991 25.1764
Rh18 GDSC1 -1.5118 -0.521 -1.5402 19.5057
HT-1080 GDSC1 -1.4333 0.1185 -1.5912 19.3849
RKN GDSC1 -0.9472 0.3583 -1.1401 13.5708
SW684 GDSC1 -0.8442 0.8309 -1.2176 13.5958
MFH-ino GDSC1 -0.8035 0.2266 -0.939 11.3792
A-204 GDSC1 -0.3483 1.4782 -1.0269 9.8643
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCUM-1 GDSC1 -4.9286 -2.2686 -4.9681 61.0998
ECC10 GDSC1 -4.4339 0.1431 -4.8722 54.3475
SCH GDSC1 -4.3265 -3.604 -4.3265 54.5084
HGC-27 GDSC1 -4.0412 -1.4255 -4.1164 50.8797
KATO III GDSC1 -3.7697 -1.0625 -3.8772 47.7328
HSC-39 GDSC1 -3.7444 -2.7119 -3.7447 47.2343
AGS GDSC1 -3.7065 -2.592 -3.7071 46.761
IM95 GDSC1 -3.6572 -1.5358 -3.6986 46.2658
RERF-GC-1B GDSC1 -3.6505 -1.0296 -3.7545 46.3278
SNU-16 GDSC1 -3.582 -2.7182 -3.5821 45.2034
NCI-N87 GDSC1 -3.2246 -0.6974 -3.3525 41.3261
RF-48 GDSC1 -3.1512 -0.7004 -3.2726 40.4118
MKN1 GDSC1 -3.0729 -0.9049 -3.1541 39.2709
NUGC-3 GDSC1 -2.8373 0.6821 -3.2977 38.1794
TGBC11TKB GDSC1 -2.6255 -0.2426 -2.7978 34.2679
Fu97 GDSC1 -2.5683 -0.9676 -2.6081 32.7778
23132/87 GDSC1 -2.4338 -1.2041 -2.4472 30.9342
MKN7 GDSC1 -2.117 0.1163 -2.3364 28.2951
SNU-5 GDSC1 -1.8578 -1.0366 -1.8625 23.68
GCIY GDSC1 -1.758 -0.0126 -1.9091 23.3881
Hs 746.T GDSC1 -1.5198 0.6096 -1.8476 21.6305
NUGC-4 GDSC1 -1.5089 3.7672 -3.2348 30.0002
MKN45 GDSC1 -0.4582 2.9319 -1.843 16.5419
MKN28 GDSC1 -0.3777 4.6873 -2.6439 21.6098
SNU-1 GDSC1 2.8866 4.6928 -0.5483 0.3149
SNG-M GDSC1 -2.8818 -1.2496 -2.9106 36.6223
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC1 -4.069 -2.123 -4.0861 51.2626
KMH-2 GDSC1 -3.5712 -2.1934 -3.5752 45.0859
TT GDSC1 -2.9424 0.4621 -3.3404 39.112
8505C GDSC1 -2.8833 -1.2461 -2.9124 36.6422
8305C GDSC1 -2.5519 -0.4814 -2.6658 33.0223
ASH-3 GDSC1 -2.5133 -1.773 -2.5137 31.8466
B-CPAP GDSC1 -2.4827 -0.6361 -2.5629 31.959
K5 GDSC1 -2.4665 -0.6717 -2.5397 31.7146
BHT-101 GDSC1 -2.0643 -0.3262 -2.1686 26.8995
CGTH-W-1 GDSC1 -1.7966 4.5701 -3.8952 34.2558
TT2609-C02 GDSC1 -1.6895 -0.1568 -1.7984 22.2521
WRO GDSC1 -1.3767 1.2032 -1.9296 21.4415
CAL-62 GDSC1 -1.3071 0.5742 -1.6058 18.7908
HTC-C3 GDSC1 -0.844 0.8772 -1.2371 13.7389
ML-1 [Human leukemia] GDSC1 1.269 8.7315 -3.3331 19.696
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-9 GDSC1 -4.7145 -1.9475 -4.7712 58.5699
BICR 22 GDSC1 -4.7071 -1.5336 -4.8116 58.1332
NCI-H3118 GDSC1 -4.647 -3.3035 -4.6476 58.4851
BICR 78 GDSC1 -4.4549 -2.7821 -4.459 56.0454
SAS GDSC1 -4.3879 -2.8126 -4.3909 55.234
PCI-06A GDSC1 -4.287 -3.4016 -4.287 54.0148
LB771-HNC GDSC1 -3.8485 -1.4501 -3.9091 48.6073
SAT [Human HNSCC] GDSC1 -3.7222 -1.1326 -3.8157 47.1537
PCI-04B GDSC1 -3.6697 -1.745 -3.6949 46.3768
SCC-15 GDSC1 -3.4019 -1.4747 -3.4361 43.1076
SKN-3 GDSC1 -3.3837 -1.3526 -3.4284 42.9258
JHU-022 GDSC1 -3.3285 -1.1819 -3.3891 42.3126
BHY GDSC1 -3.2753 -0.602 -3.4259 42.0208
JHU-011 GDSC1 -3.1558 -1.4932 -3.1778 39.9974
KOSC-2 GDSC1 -3.1418 -0.6013 -3.2814 40.378
CAL-27 GDSC1 -3.084 -2.0196 -3.0856 38.9874
DOK GDSC1 -2.9827 -1.2619 -3.0153 37.9001
PE/CA-PJ15 GDSC1 -2.9611 -1.1582 -3.0027 37.682
OSC-20 GDSC1 -2.6849 1.3878 -3.388 37.4935
Ca9-22 GDSC1 -2.515 -1.7468 -2.5154 31.8677
PCI-38 GDSC1 -2.464 -1.1191 -2.4843 31.3547
HO-1-N-1 GDSC1 -2.3739 -1.0131 -2.3987 30.2572
PCI-15A GDSC1 -2.2641 -0.438 -2.3627 29.3527
BICR 31 GDSC1 -2.1246 0.264 -2.3883 28.6699
HSC-4 GDSC1 -2.0796 1.0596 -2.6159 29.7997
HO-1-u-1 GDSC1 -1.9124 -0.9085 -1.9251 24.4131
BB30-HNC GDSC1 -1.8646 0.7669 -2.2758 26.433
FaDu GDSC1 -1.7515 0.1489 -1.9471 23.6052
CAL-33 GDSC1 -1.7495 -0.5632 -1.7877 22.5394
PCI-30 GDSC1 -1.6519 2.2952 -2.6901 27.831
SCC-25 GDSC1 -1.5919 0.7528 -1.9779 22.9217
KON GDSC1 -1.5419 -0.2062 -1.6267 20.2495
OSC-19 GDSC1 -1.3716 -0.5742 -1.3863 17.6656
BICR 10 GDSC1 -1.3383 0.7972 -1.724 19.7916
HSC-3 GDSC1 -0.6338 0.263 -0.768 9.2578
BB49-HNC GDSC1 -0.6237 4.1486 -2.594 22.3318
HSC-2 GDSC1 -0.5716 0.0722 -0.6377 8.0091
Detroit 562 GDSC1 0.5004 4.1804 -1.6643 11.6665
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-3 GDSC1 -3.5778 -0.4748 -3.7813 45.6953
KU-19-19 GDSC1 -3.3903 -2.5264 -3.3904 42.807
647V GDSC1 -3.146 -1.3007 -3.1833 39.9548
HT-1197 GDSC1 -3.1082 -1.0103 -3.1767 39.6421
BFTC-905 GDSC1 -3.0003 -0.8772 -3.0804 38.3718
RT-112 GDSC1 -2.7772 -2.0497 -2.7773 35.1431
HT-1376 GDSC1 -2.5726 -1.6417 -2.5744 32.5968
CAL-29 GDSC1 -2.4153 -1.3772 -2.4206 30.6525
J82 GDSC1 -2.3966 -0.4581 -2.5022 31.0453
5637 GDSC1 -2.1743 -0.978 -2.1928 27.7225
639V GDSC1 -2.0423 -0.6205 -2.0926 26.2762
TCCSUP GDSC1 -2.0333 -1.1452 -2.0381 25.8742
RT-4 GDSC1 -1.6602 0.1076 -1.8355 22.3316
SW780 GDSC1 -1.5042 0.1754 -1.6853 20.4272
SW1710 GDSC1 -1.44 -0.2114 -1.5148 18.9109
T24 GDSC1 -0.9555 0.6923 -1.2766 14.5903
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NEC8 GDSC1 -7.3314 -5.5302 -7.3316 88.1848
TC-YIK GDSC1 -6.4609 -2.9991 -6.5112 75.0947
PA-1 GDSC1 -4.9104 -3.843 -4.9104 61.7962
NCC-IT GDSC1 -4.7616 -3.1051 -4.7642 59.831
HT-3 GDSC1 -4.1718 -2.7954 -4.1733 52.5666
NT2-D1 GDSC1 -4.1361 -2.3181 -4.1467 52.0945
Ca Ski GDSC1 -3.6053 -1.4125 -3.6561 45.6585
JAR GDSC1 -3.4307 -2.7921 -3.4307 43.3111
HEY GDSC1 -3.4211 -1.3301 -3.4703 43.4031
BPH-1 GDSC1 -3.1789 0.0794 -3.4848 41.4539
JEG-3 GDSC1 -3.0543 -2.1946 -3.0546 38.6081
SKG-IIIa GDSC1 -2.7724 -1.738 -2.7748 35.0972
C-33 A GDSC1 -2.5722 -1.7032 -2.5733 32.5869
MS751 GDSC1 -2.5027 -0.4884 -2.6112 32.3805
DSH1 GDSC1 -2.4867 -0.268 -2.6406 32.4545
ME-180 GDSC1 -2.452 -0.5947 -2.5369 31.6061
SW954 GDSC1 -2.4309 -1.2963 -2.4395 30.8677
KGN GDSC1 -2.4067 0.6229 -2.8108 32.918
HEC-1 GDSC1 -2.2757 -1.6507 -2.2759 28.8749
OMC-1 [Human cervical carcinoma] GDSC1 -2.2724 -0.5475 -2.3515 29.3328
C-4-I GDSC1 -2.2409 -0.2987 -2.3664 29.2342
PWR-1E GDSC1 -2.2197 -0.919 -2.2454 28.3363
DoTc2 4510 GDSC1 -2.1208 -0.0242 -2.3019 28.097
SiSo GDSC1 -2.087 -0.4275 -2.173 27.0636
OVCA433 GDSC1 -2.0608 -0.9683 -2.0753 26.2795
LB831-BLC GDSC1 -1.9571 -0.4519 -2.0282 25.3458
OVCA420 GDSC1 -1.9016 -0.6053 -1.9443 24.4694
UWB1.289 GDSC1 -1.7411 0.3519 -1.9985 23.8909
SW756 GDSC1 -1.6451 0.8499 -2.0715 23.8507
SW962 GDSC1 -1.553 -0.4542 -1.5932 20.0968
CAL-39 GDSC1 -1.503 0.752 -1.8824 21.7812
ACC-OV7 GDSC1 -1.0327 0.6719 -1.3501 15.5206
SKN GDSC1 -0.8007 0.4955 -1.0342 12.0391
HeLa GDSC1 -0.7231 3.181 -2.2076 20.2547
OVMIU GDSC1 -0.6722 1.0537 -1.1398 12.1804
SiHa GDSC1 -0.5051 1.462 -1.1672 11.6247
JHOS-3 GDSC1 -0.3651 1.9838 -1.2905 11.9788
PEO1 GDSC1 1.6219 6.8374 -2.1524 11.7543
OV17R GDSC1 1.9539 7.6351 -2.31 11.8927
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

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4 A trichostatin A expression signature identified by TempO-Seq targeted whole transcriptome profiling. PLoS One. 2017 May 25;12(5):e0178302. doi: 10.1371/journal.pone.0178302. eCollection 2017.
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