Details of the Drug

General Information of Drug (ID: DMAH59S)

Drug Name
Amonafide
Synonyms Quinamed (TN)
Indication
Disease Entry ICD 11 Status REF
Breast cancer 2C60-2C65 Phase 3 [1]
Ovarian cancer 2C73 Phase 3 [1]
Prostate cancer 2C82.0 Phase 3 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C16H17N3O2
Canonical SMILES
CN(C)CCN1C(=O)C2=CC=CC3=CC(=CC(=C32)C1=O)N
InChI
1S/C16H17N3O2/c1-18(2)6-7-19-15(20)12-5-3-4-10-8-11(17)9-13(14(10)12)16(19)21/h3-5,8-9H,6-7,17H2,1-2H3
InChIKey
UPALIKSFLSVKIS-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
50515
ChEBI ID
CHEBI:94661
CAS Number
69408-81-7
UNII
1Q8D39N37L
DrugBank ID
DB05022
TTD ID
D0HR7P
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

References

1 ClinicalTrials.gov (NCT00715637) Phase III Randomized Study of Amonafide (AS1413) and Cytarabine Versus Daunorubicin and Cytarabine in Patients With Secondary Acute Myeloid Leukemia (AML)- the ACCEDEStudy. U.S. National Institutes of Health.