Details of the Drug

General Information of Drug (ID: DMB5A80)

Drug Name
SNX-2112
Synonyms
SNX-2112; 908112-43-6; SNX 2112; 4-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide; UNII-10C9P3FFOW; PF-04928473; 10C9P3FFOW; CHEMBL560895; SNX-2112 (PF-04928473); 945626-71-1; 4-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-5,7-dihydroindazol-1-yl]-2-[(4-hydroxycyclohexyl)amino]benzamide; 4-[6,6-Dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]-2-[(cis-4-hydroxycyclohexyl)amino]benzamide
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 464.5
Logarithm of the Partition Coefficient (xlogp) 3.8
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C23H27F3N4O3
IUPAC Name
4-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-5,7-dihydroindazol-1-yl]-2-[(4-hydroxycyclohexyl)amino]benzamide
Canonical SMILES
CC1(CC2=C(C(=O)C1)C(=NN2C3=CC(=C(C=C3)C(=O)N)NC4CCC(CC4)O)C(F)(F)F)C
InChI
InChI=1S/C23H27F3N4O3/c1-22(2)10-17-19(18(32)11-22)20(23(24,25)26)29-30(17)13-5-8-15(21(27)33)16(9-13)28-12-3-6-14(31)7-4-12/h5,8-9,12,14,28,31H,3-4,6-7,10-11H2,1-2H3,(H2,27,33)
InChIKey
ZFVRYNYOPQZKDG-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
24772860
CAS Number
908112-43-6
UNII
10C9P3FFOW
DrugBank ID
DB17055
TTD ID
D0K0TJ
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Heat shock protein 90 alpha (HSP90A) TT78R5H HS90A_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [2]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [2]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [2]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [2]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Gene/Protein Processing [2]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Gene/Protein Processing [2]
Cytochrome c (CYCS) OTBFALJD CYC_HUMAN Protein Interaction/Cellular Processes [2]
Endoplasmic reticulum chaperone BiP (HSPA5) OTFUIRAO BIP_HUMAN Gene/Protein Processing [2]
Endoplasmin (HSP90B1) OT02XLBR ENPL_HUMAN Gene/Protein Processing [2]
Heat shock protein 75 kDa, mitochondrial (TRAP1) OTNG0L8J TRAP1_HUMAN Gene/Protein Processing [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Heat shock protein 90 alpha (HSP90A) DTT HSP90AA1 3.96E-01 0.18 0.48
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 -2.8323 6.4763 -5.1889 51.0358
ES7 GDSC1 -5.5442 -3.3626 -5.5461 82.7234
EW-7 GDSC1 -5.0768 -3.5914 -5.0769 79.619
EW-1 GDSC1 -4.9447 -2.8464 -4.9473 76.9149
TC-71 GDSC1 -4.7883 -3.113 -4.7888 76.0071
MHH-ES-1 GDSC1; CTRP2 -4.7643 -2.9204 -4.7643 65.3359
ES1 GDSC1 -4.6931 -0.0427 -4.9231 68.2308
EW-13 GDSC1 -4.4875 -2.6949 -4.4888 72.3528
ES8 GDSC1 -4.1035 2.8007 -5.0509 60.1382
ES5 GDSC1 -4.1005 0.2203 -4.3316 63.7358
H-EMC-SS GDSC1 -3.9163 1.0409 -4.3149 61.1402
SK-ES-1 GDSC1; CTRP2 -3.5347 0.7946 -3.5808 57.7758
CADO-ES1 GDSC1 -2.6002 1.0939 -2.8928 49.5467
EW-18 GDSC1 -2.477 6.0121 -4.6205 49.0076
EW-3 GDSC1 -2.3489 5.0055 -4.0476 48.0274
EW-11 GDSC1 -2.1522 1.9126 -2.6379 45.1338
ES6 GDSC1 -2.0134 4.5527 -3.5056 45.405
NOS-1 [Human HNSCC] GDSC1 -1.5994 2.6645 -2.3017 39.9901
EW-16 GDSC1 -1.4837 5.4127 -3.3447 41.8986
ES4 GDSC1 -1.4535 18.9546 -9.8818 46.8488
CAL-78 GDSC1; CTRP2 -1.3911 6.2281 -2.3344 44.3588
TC71 CTRP2 -1.3517 5.8847 -2.1822 44.0035
SJSA-1 GDSC1; CTRP2 -1.3312 5.2367 -1.9669 43.6264
A-673 GDSC1; CTRP2 -1.2523 4.4808 -1.6821 42.8343
SK-PN-DW GDSC1 -0.8775 4.7235 -2.4217 35.8549
CHSA8926 GDSC1 -0.5276 2.365 -1.0421 26.9171
SK-N-MC CTRP2 -0.3384 5.993 -1.114 37.9499
HOS GDSC1; CTRP2 -0.1549 6.2927 -1.0138 37.0298
G-292 clone A141B1 GDSC1; CTRP2 -0.0434 4.6254 -0.3748 35.9355
U2OS GDSC1; CTRP2; CTRP1 0.3343 6.2415 -0.4663 33.8599
EW-24 GDSC1 0.9151 6.2166 -1.4507 22.5006
NY GDSC1 1.0407 6.9819 -1.7238 23.5417
SW1353 CTRP2 1.8636 8.2846 0.3589 26.5042
Hs 888.T CTRP2 2.2886 12.2961 -0.988 30.1894
HuO9 GDSC1 2.6996 10.3737 -2.0879 19.7588
SaOS-2 GDSC1; CTRP2 2.8039 9.0173 1.0578 22.4703
HuO-3N1 GDSC1 2.9661 7.8506 -0.6671 10.616
CHSA0011 GDSC1 3.1313 9.4411 -1.3196 14.3012
CHSA0108 GDSC1 3.8114 6.0395 0.6092 1.078
CAL-72 GDSC1 3.881 5.4528 0.8499 0.2583
MG-63 GDSC1; CTRP2 5.9239 11.4852 2.5244 8.9799
Hs 822.T CTRP2 6.3766 7.3336 4.8929 0.1921
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 211 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -4.7318 -1.8257 -4.7334 64.9689
MEC1 CTRP2 -4.6467 -2.6283 -4.6468 64.5452
JM1 GDSC1; CTRP2 -4.8024 -1.7765 -4.8046 65.3946
NKM-1 GDSC1 -6.939 -4.904 -6.9392 93.6751
KHM-1B CTRP2 -6.8969 0.728 -7.1124 72.2912
Ri-1 CTRP2 -6.8134 -3.322 -6.8153 77.6405
OCI-AML-2 GDSC1; CTRP2 -6.2064 -5.382 -6.2064 74.9544
GA-10 CTRP2 -6.1154 -4.797 -6.1154 74.3414
SIG-M5 GDSC1; CTRP2 -6.0169 -5.1846 -6.0169 73.6916
MOLM-13 GDSC1; CTRP2 -5.9901 -4.7066 -5.9901 73.5089
RPMI-8866 GDSC1 -5.834 -4.0999 -5.8342 86.856
CESS GDSC1 -5.7899 -3.6943 -5.791 85.2491
NB4 GDSC1; CTRP2 -5.7411 -4.5908 -5.7411 71.8537
DND-41 GDSC1 -5.7252 -4.6132 -5.7252 87.5624
CCRF-CEM GDSC1 -5.6755 -4.096 -5.6755 85.8191
KE-37 GDSC1; CTRP2 -5.6464 -3.9774 -5.6464 71.2063
WIL2 NS GDSC1 -5.6207 -3.9778 -5.6208 85.0917
ALL-PO GDSC1 -5.5965 -3.5521 -5.5975 83.6466
NALM-6 GDSC1; CTRP2 -5.5916 -3.6468 -5.5916 70.8164
ML-2 GDSC1 -5.5898 -4.6252 -5.5898 86.3485
QIMR-WIL GDSC1 -5.5878 -3.6959 -5.5883 84.0343
H9 GDSC1 -5.5241 -4.0479 -5.5242 84.5508
Karpas-45 GDSC1 -5.5078 -4.0873 -5.5078 84.513
BL-41 GDSC1 -5.4707 -4.3982 -5.4707 84.8072
SU-DHL-16 GDSC1 -5.4706 -4.7338 -5.4706 85.209
Ku812 GDSC1; CTRP2; CTRP1 -5.4629 -3.0887 -5.463 69.9198
MY-M12 GDSC1 -5.4384 1.5609 -6.1159 68.616
MOLM-16 CTRP2; CTRP1 -5.4258 -3.6396 -5.4259 69.734
SR GDSC1; CTRP2 -5.4159 -3.6049 -5.4159 69.666
Loucy GDSC1 -5.3899 -4.4875 -5.3899 84.0889
JSC-1 GDSC1 -5.3735 -1.3029 -5.469 75.278
EoL-1 GDSC1; CTRP2 -5.3331 -4.6959 -5.3331 69.1363
KOPN-8 GDSC1 -5.3301 -3.4529 -5.3308 81.5037
CTB-1 GDSC1 -5.3117 -2.8658 -5.3173 79.7087
VL51 GDSC1 -5.3079 -3.8374 -5.308 82.2354
SU-DHL-8 GDSC1; CTRP2 -5.2922 -0.676 -5.3227 67.5289
SU-DHL-10 GDSC1; CTRP2 -5.26 -3.7399 -5.26 68.6441
YT GDSC1 -5.2547 -3.4725 -5.2551 80.9567
AMO1 GDSC1; CTRP2; CTRP1 -5.2186 -2.4383 -5.2194 68.1805
MOLT-16 GDSC1; CTRP2 -5.2087 -3.4513 -5.2087 68.2935
Daudi GDSC1; CTRP2 -5.1856 -3.7751 -5.1856 68.1512
CTV-1 GDSC1 -5.1687 -4.001 -5.1687 81.1594
Kasumi-1 CTRP2 -5.166 -3.1738 -5.166 67.9929
HC-1 GDSC1 -5.1407 -2.7551 -5.1462 78.2116
MC116 GDSC1; CTRP2; CTRP1 -5.1206 -3.9615 -5.1206 67.7515
WSU-NHL GDSC1 -5.1118 -3.6089 -5.1119 79.9845
HuNS1 CTRP2 -5.1078 -3.1065 -5.1078 67.6063
Reh GDSC1; CTRP2 -5.0978 -0.8922 -5.1169 66.6676
U-937 CTRP2; CTRP1 -5.0821 -3.9061 -5.0821 67.4636
SKM-1 CTRP2; CTRP1 -5.0736 -3.9737 -5.0736 67.4072
Sc-1 GDSC1 -5.0578 -3.6448 -5.0578 79.5193
GDM-1 GDSC1; CTRP2; CTRP1 -5.0396 -2.5881 -5.0398 67.0925
SUP-M2 GDSC1; CTRP2 -5.0266 -3.9097 -5.0266 67.0944
TUR GDSC1 -5.009 -1.0985 -5.1059 72.7071
SU-DHL-6 GDSC1; CTRP2 -4.9895 -3.9263 -4.9895 66.8474
Ki-JK CTRP2 -4.9629 -3.3561 -4.9629 66.6652
MOLP-8 GDSC1; CTRP2 -4.9425 -3.014 -4.9425 66.5153
DoHH2 CTRP2 -4.9305 -2.9162 -4.9306 66.4294
697 GDSC1; CTRP2 -4.9119 -3.4211 -4.9119 66.3275
NCI-H929 CTRP2 -4.9033 -2.4501 -4.9036 66.1947
KMS-26 CTRP2 -4.8908 -4.1339 -4.8908 66.1896
MOLT-3 CTRP2 -4.8792 -3.2039 -4.8792 66.1063
OCI-Ly19 GDSC1; CTRP2 -4.8595 -3.4343 -4.8595 65.9795
PL21 CTRP2; CTRP1 -4.841 -1.4954 -4.8456 65.5287
MM1.S CTRP2 -4.8129 -2.9284 -4.8129 65.6567
P32/ISH GDSC1 -4.7922 -3.2511 -4.7924 76.2515
PF-382 GDSC1; CTRP2 -4.7802 -2.9906 -4.7802 65.4435
ARH-77 GDSC1 -4.7757 -1.36 -4.8348 71.9125
Farage GDSC1 -4.7305 1.8224 -5.4193 64.8687
KE-97 CTRP2; CTRP1 -4.7243 -3.092 -4.7243 65.1099
KYO-1 CTRP2 -4.7223 -2.8958 -4.7223 65.057
VAL GDSC1 -4.7194 -3.4597 -4.7194 75.6985
BV-173 GDSC1; CTRP2 -4.7076 -3.0145 -4.7076 64.9639
RS4;11 GDSC1; CTRP2 -4.6997 -1.6928 -4.7019 64.7318
MOLT-4 GDSC1 -4.6961 -3.5139 -4.6961 75.4756
Hs 445 GDSC1 -4.6955 -2.8623 -4.6967 74.6895
Mino CTRP2 -4.6639 -2.8879 -4.6639 64.6705
HH [Human lymphoma] GDSC1; CTRP2 -4.6609 2.8188 -5.0332 61.5999
KMOE-2 GDSC1 -4.6477 -3.4924 -4.6477 74.902
RPMI-6666 GDSC1; CTRP2 -4.6349 -1.5077 -4.6381 64.274
MOLM-6 CTRP2 -4.6245 -2.8583 -4.6245 64.4088
JURL-MK1 GDSC1; CTRP2 -4.6205 -3.3364 -4.6205 64.3883
P30/OHK GDSC1 -4.61 -3.8547 -4.61 74.5652
THP-1 GDSC1; CTRP2; CTRP1 -4.5661 -2.2737 -4.5664 63.9883
BC-1 GDSC1 -4.5618 -2.1662 -4.5714 72.1517
ALL-SIL GDSC1; CTRP2 -4.5569 -3.1993 -4.5569 63.9646
ATN-1 GDSC1 -4.5426 -2.9584 -4.543 73.2603
MV4-11 GDSC1; CTRP2 -4.5418 -1.6157 -4.5438 63.7213
OCI-AML-3 GDSC1; CTRP2; CTRP1 -4.468 -2.1074 -4.4683 63.3312
EM-2 GDSC1; CTRP2 -4.4646 -2.8905 -4.4646 63.3483
WSU-DLCL2 GDSC1; CTRP2; CTRP1 -4.4566 -3.2997 -4.4566 63.2972
NOMO-1 GDSC1; CTRP2; CTRP1 -4.4451 -2.1051 -4.4453 63.1814
MLMA GDSC1 -4.4369 -1.568 -4.4674 69.8416
KCL-22 GDSC1; CTRP2 -4.4298 -1.9277 -4.4303 63.0618
SU-DHL-4 GDSC1; CTRP2; CTRP1 -4.403 -3.2879 -4.403 62.9399
NU-DUL-1 GDSC1; CTRP2; CTRP1 -4.3837 -1.2016 -4.388 62.6233
U-698-M GDSC1 -4.3819 6.7307 -6.8935 58.1014
SEM CTRP2 -4.3759 -1.5244 -4.3775 63.6192
MHH-CALL-4 CTRP2 -4.3706 -0.9487 -4.378 62.4671
OPM-2 GDSC1; CTRP2 -4.3501 -3.2157 -4.3501 62.5873
BC-3 GDSC1 -4.3464 -2.4106 -4.3491 70.5152
JVM-3 GDSC1; CTRP2 -4.3338 -2.0679 -4.334 62.4505
LAMA-84 GDSC1; CTRP2 -4.2997 -2.5587 -4.2998 56.4738
NCO2 CTRP2 -4.2978 -2.7691 -4.2978 62.2377
KMS-12-BM GDSC1; CTRP2 -4.2929 -0.5906 -4.306 61.8693
Ramos.2G6.4C10 GDSC1 -4.2916 -2.8184 -4.2919 70.3515
KMS-27 CTRP2 -4.2605 -1.9231 -4.2609 61.9587
Namalwa GDSC1; CTRP2 -4.2595 -2.84 -4.2595 61.983
BL-70 CTRP2; CTRP1 -4.2462 -2.2003 -4.2462 61.9187
OCI-AML-5 GDSC1; CTRP2 -4.2401 -2.6523 -4.2401 62.837
A4/Fukuda GDSC1; CTRP2 -4.2244 -2.3434 -4.2244 61.7431
GR-ST GDSC1 -4.2113 0.3472 -4.477 64.3123
CML-T1 CTRP2 -4.2091 -2.5058 -4.2091 61.6452
A3/Kawakami GDSC1; CTRP2 -4.1944 -2.2014 -4.1944 61.5399
SUP-HD1 GDSC1; CTRP2 -4.1727 -1.935 -4.1729 61.3832
EB2 GDSC1 -4.1704 -0.5758 -4.2784 65.6933
HuT 78 CTRP2 -4.168 -1.7312 -4.1685 62.3165
HPB-ALL CTRP2 -4.1659 0.1148 -4.2001 60.8299
L-363 GDSC1; CTRP2 -4.1578 -0.9998 -4.1625 61.1552
MHH-PREB-1 GDSC1 -4.1443 0.8036 -4.5053 63.0838
SU-DHL-5 GDSC1; CTRP1 -4.139 -3.2224 -4.139 53.3537
M-07e CTRP2 -4.1282 -0.4727 -4.1403 61.7814
Pfeiffer CTRP2 -4.0878 -2.1697 -4.0879 60.8334
KMS-21-BM CTRP2 -4.0759 -2.1953 -4.0759 60.755
MJ CTRP2 -4.0681 -1.4172 -4.0693 60.6525
K-562 GDSC1; CTRP2 -4.0289 -0.8938 -4.0338 60.317
BE-13 GDSC1 -4.0202 -1.4632 -4.0429 65.8956
KMS-34 CTRP2 -3.9999 -0.9276 -4.0042 60.139
P12-Ichikawa GDSC1; CTRP2 -3.9702 -1.9503 -3.9703 60.048
MEG-01 GDSC1 -3.9669 -1.0476 -4.0144 64.7591
PL-21 GDSC1 -3.9595 2.8772 -4.9215 59.2275
JJN-3 GDSC1; CTRP2 -3.9574 -2.6847 -3.9574 60.9588
SU-DHL-1 GDSC1; CTRP2 -3.9469 -3.5838 -3.9469 59.9014
RPMI-8402 GDSC1; CTRP2 -3.9246 -1.7203 -3.9249 59.7375
OCI-Ly3 CTRP2 -3.8998 -1.2616 -3.9012 59.541
DEL GDSC1; CTRP2 -3.8951 -1.8869 -3.8952 59.5486
HL-60 GDSC1; CTRP2 -3.8937 -1.453 -3.8944 59.5179
Peer CTRP2 -3.8801 -1.5249 -3.8806 59.4337
P31/FUJ GDSC1; CTRP2 -3.8755 -1.4786 -3.8761 59.4005
KMS-11 GDSC1; CTRP2; CTRP1 -3.8674 -1.9681 -3.8675 59.3671
SUP-T1 GDSC1; CTRP2 -3.862 2.3358 -4.0923 58.0752
CA46 GDSC1; CTRP2 -3.7729 2.6521 -4.0465 57.4619
KMS-18 CTRP2 -3.7564 -1.2604 -3.7574 58.6035
AML-193 CTRP2 -3.7213 -2.4766 -3.7213 59.3887
HAL-01 GDSC1 -3.613 -2.0591 -3.6143 62.0016
U266B1 GDSC1; CTRP2 -3.5546 -0.3774 -3.5613 58.1778
KMS-28BM CTRP2 -3.4894 2.0721 -3.6575 56.1656
Hs 611.T CTRP2 -3.4349 -0.5903 -3.4386 56.4471
KMS-20 CTRP2 -3.3775 -2.1415 -3.3775 57.1028
RCH-ACV CTRP2 -3.3487 4.7618 -4.0396 54.5375
OCI-M1 GDSC1; CTRP2 -3.3472 -1.3127 -3.3474 55.9019
Kasumi-2 CTRP2 -3.3262 2.002 -3.4657 56.164
SET-2 CTRP2 -3.3035 -1.4128 -3.3037 55.6131
KG-1 GDSC1 -3.278 -1.0148 -3.3006 57.5874
TK [Human B-cell lymphoma] GDSC1 -3.2489 -0.1539 -3.3521 56.7057
KY821 GDSC1 -3.2237 3.7103 -4.4364 54.0557
EHEB CTRP2 -3.1714 2.3655 -3.3577 54.2708
Karpas-422 GDSC1; CTRP2 -3.1202 -0.3805 -3.1238 54.3713
RL GDSC1; CTRP2 -2.9818 1.9389 -3.1029 53.2348
EJM GDSC1; CTRP2; CTRP1 -2.9714 1.9591 -3.094 53.1686
DB GDSC1; CTRP2 -2.9492 4.1328 -3.4483 52.675
HT GDSC1; CTRP2; CTRP1 -2.9457 1.6758 -3.0373 53.0958
Karpas-299 GDSC1; CTRP2 -2.9434 1.5345 -3.0228 53.0569
HEL GDSC1; CTRP2 -2.93 0.5952 -2.9699 49.9364
Ci-1 CTRP2 -2.9186 1.5955 -3.0021 52.8957
L-1236 GDSC1; CTRP2 -2.9097 0.0262 -2.9166 52.9694
Jiyoye GDSC1 -2.8862 1.152 -3.2195 52.4108
SUP-B15 GDSC1; CTRP2 -2.8741 -0.1429 -2.8783 52.7406
P3HR-1 CTRP2; CTRP1 -2.8272 3.6505 -3.2078 52.1258
CMK CTRP2 -2.7759 4.551 -3.3607 51.6995
NU-DHL-1 CTRP2 -2.5989 -0.8172 -2.5991 51.925
TALL-1 [Human adult T-ALL] CTRP2 -2.598 5.9139 -3.5487 50.6845
Jurkat CTRP2 -2.5897 0.9349 -2.6822 43.5803
HEL 92.1.7 CTRP2 -2.5489 0.4558 -2.5595 50.5831
Mono-Mac-1 CTRP2 -2.5234 11.4147 -5.531 50.2217
MOLP-2 CTRP2 -2.4027 1.9799 -2.4958 49.6311
MOLT-13 GDSC1; CTRP2 -2.3902 1.4897 -2.4418 49.5435
SCC-3 GDSC1 -2.3676 0.9182 -2.597 46.9942
Raji GDSC1; CTRP2 -2.3518 2.6017 -2.5153 49.3248
RPMI-8226 GDSC1; CTRP2; CTRP1 -2.2727 1.6246 -2.3291 48.7833
JVM-2 GDSC1; CTRP2 -2.231 3.5381 -2.8529 42.0846
KM-H2 GDSC1; CTRP2 -2.1659 1.7895 -2.354 40.6486
BALL-1 GDSC1 -2.1346 10.8523 -6.5423 47.9256
SUP-T11 CTRP2 -2.0858 4.0401 -2.4875 47.8199
F-36P CTRP2 -1.7934 9.266 -3.8259 47.8281
LC4-1 GDSC1 -1.7412 5.0873 -3.4594 43.6295
MOTN-1 CTRP2 -1.5433 4.49 -2.0015 44.6457
L-540 GDSC1; CTRP2 -1.4955 3.3008 -1.7035 43.9822
EB1 CTRP2 -1.4167 9.4191 -3.5447 45.5472
RC-K8 GDSC1 -1.3248 6.7426 -3.8024 41.8783
SK-MM-2 GDSC1; CTRP2 -1.2818 6.2281 -2.2157 43.7413
MN-60 GDSC1 -1.2768 5.6513 -3.2466 40.5154
ST486 GDSC1; CTRP2 -1.2638 16.5742 -6.5577 46.5612
Granta-519 GDSC1; CTRP2 -1.2038 6.6426 -2.2693 43.4773
OCI-Ly10 CTRP2; CTRP1 -1.0336 3.5545 -1.2494 41.0383
TF-1 CTRP2 -0.9351 3.7195 -1.1731 40.454
JeKo-1 CTRP2 -0.6079 21.8091 -8.4141 45.6645
LP-1 GDSC1; CTRP2; CTRP1 -0.3136 5.9273 -1.0659 37.7447
Mono-Mac-6 GDSC1; CTRP2 -0.2415 38.0083 -16.0263 46.8655
L-428 GDSC1; CTRP2 0.3915 6.1972 -0.348 34.306
ME1 GDSC1 0.4118 6.3451 -1.9633 27.4244
KO52 CTRP2 0.4908 11.1037 -2.2919 37.4271
ME1 CTRP2 0.6071 6.26 -0.1773 32.094
MHH-CALL-3 CTRP2 0.8437 15.8595 -4.1666 39.1546
HDLM-2 GDSC1; CTRP2 1.0356 6.8944 0.0546 29.9894
HD-MY-Z CTRP2 1.6112 11.0341 -1.1372 31.6108
ROS-50 GDSC1 1.78 7.9654 -1.6023 20.1192
DG-75 GDSC1 4.0897 14.6745 -3.1853 20.8853
Karpas-620 GDSC1; CTRP2 6.5766 7.8058 4.6388 0.2334
REC-1 CTRP2 6.8813 8.8064 4.3849 0.6764
KMM-1 CTRP2 7.3841 20.2425 -0.7039 18.0438
⏷ Show the Full List of 211 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 -0.3101 8.4874 -2 39.6004
TE15 CTRP2 -0.269 8.0243 -1.7726 39.0466
KYSE-270 GDSC1 -3.5441 0.5214 -3.789 58.8644
KYSE-30 CTRP2 -3.2683 1.1461 -3.3265 56.0708
KYSE-180 GDSC1; CTRP2 -2.5592 1.2467 -2.6016 50.6389
KYSE-450 GDSC1; CTRP2; CTRP1 -2.5288 1.1762 -2.5659 50.4899
TE-5 GDSC1; CTRP2 -2.3837 0.6649 -2.3968 49.4919
KYSE-510 GDSC1; CTRP2 -2.3266 1.1889 -2.3552 50.1124
KYSE-140 GDSC1; CTRP2; CTRP1 -1.9679 3.6424 -2.2745 47.0938
TE-14 CTRP2 -1.9163 7.2862 -3.2191 48.1313
KYSE-410 GDSC1; CTRP2; CTRP1 -1.8598 4.8072 -2.4244 46.6647
TE-15 GDSC1 -1.3525 16.6841 -8.6676 46.1507
T.T GDSC1 -1.0271 4.6221 -2.5262 37.0798
KYSE-150 GDSC1; CTRP2 -0.3332 6.2727 -1.1599 38.9631
TE-8 GDSC1 -0.0687 8.3481 -3.3882 35.0053
KYSE-520 GDSC1; CTRP2 0.2613 7.8729 -1.1497 35.8666
TE-4 GDSC1; CTRP2 0.5469 6.2058 -0.2238 32.4344
OE21 GDSC1; CTRP2 0.583 9.1063 -1.3199 35.1809
TE-6 GDSC1; CTRP2 1.036 9.8708 -1.1866 33.4363
TE-10 GDSC1; CTRP2 1.1858 9.2709 -0.7686 31.915
KYSE-70 GDSC1; CTRP2 1.7352 7.8547 0.4096 26.7067
TE-11 GDSC1; CTRP2 1.9425 6.3445 1.2327 23.2032
TE-9 GDSC1; CTRP2 2.3148 4.5005 2.1945 18.5978
TE-1 GDSC1; CTRP2 3.0748 10.4794 0.5507 22.6048
EC-GI-10 GDSC1; CTRP2 3.5713 14.0362 -0.7313 25.4808
OE33 GDSC1; CTRP2 3.633 13.239 -0.2814 23.9979
OE19 GDSC1; CTRP2 3.7726 18.3046 -2.6732 29.7805
COLO 680N GDSC1; CTRP2 5.7703 12.8393 1.7342 12.4142
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 -1.3939 4.0856 -1.7452 43.5783
BxPC-3 GDSC1; CTRP2 -4.4707 -0.9625 -4.479 63.0834
MZ-PC-1 GDSC1 -3.7968 1.1668 -4.2169 60.1097
PaTu 8988s CTRP2 -3.5793 4.7129 -4.2785 55.6404
Panc 03.27 GDSC1; CTRP2; CTRP1 -3.3273 -1.322 -3.3275 55.8128
HuP-T4 GDSC1; CTRP2; CTRP1 -2.9404 2.7108 -3.1601 52.9076
PSN1 GDSC1; CTRP2 -2.7186 5.9784 -3.7 51.2695
KP-4 GDSC1; CTRP2 -2.6161 2.973 -2.8549 50.9326
PaTu 8902 GDSC1; CTRP2; CTRP1 -1.8101 3.1643 -2.0181 46.0207
Hs 766T GDSC1; CTRP2 -1.6509 3.2377 -1.8459 45.913
Panc 08.13 GDSC1; CTRP2 -1.2274 4.927 -1.7403 53.375
PaTu 8988t GDSC1; CTRP2 -1.0705 4.683 -1.5339 41.7759
PK-59 CTRP2 -0.8981 6.0263 -1.7333 41.406
Panc 05.04 CTRP2 -0.798 8.6861 -2.5958 42.2831
PK-45H CTRP2 -0.6249 6.403 -1.5606 39.995
TCC-Pan2 CTRP2 -0.57 7.5144 -1.8985 40.39
KP-3 GDSC1; CTRP2; CTRP1 -0.4618 6.3702 -1.369 39.0309
SW1990 GDSC1; CTRP2 -0.1522 3.0427 -0.2315 34.8768
QGP-1 GDSC1; CTRP2; CTRP1 -0.0537 18.603 -6.3345 43.3981
Panc 10.05 GDSC1; CTRP2; CTRP1 -0.0101 8.1935 -1.5095 38.4638
HPAF-II GDSC1; CTRP2 0.1567 5.9741 -0.5697 34.7664
DAN-G GDSC1; CTRP2 0.2303 13.6186 -3.7051 40.282
HPAC GDSC1; CTRP2; CTRP1 0.4474 15.3155 -4.2825 40.3729
KP-2 GDSC1; CTRP2 0.9278 7.1106 -0.1431 30.9435
AsPC-1 GDSC1; CTRP2 1.0266 7.6679 -0.2575 30.972
SUIT-2 GDSC1; CTRP2; CTRP1 1.0616 6.1684 0.35 29.0193
Capan-2 GDSC1; CTRP2; CTRP1 1.0962 6.2523 0.3979 29.699
PL4 GDSC1 1.1061 6.89 -1.6218 22.7189
CFPAC-1 GDSC1; CTRP2; CTRP1 1.7419 8.2229 0.2656 27.231
HuP-T3 GDSC1; CTRP2 2.0099 10.6886 -0.5824 29.004
YAPC GDSC1; CTRP2 2.273 9.2914 0.3255 25.4684
MIA PaCa-2 GDSC1; CTRP2 2.9569 7.4939 1.8278 18.1497
SU.86.86 GDSC1; CTRP2 2.9794 13.3963 -0.9565 27.5201
SNU-213 CTRP2 3.1681 13.4529 -0.8103 26.657
L3.3 CTRP2 3.5643 12.1912 0.1733 22.7025
Panc 04.03 GDSC1; CTRP2 4.4706 15.1749 -0.5066 22.8301
Capan-1 GDSC1; CTRP2 5.2665 14.8771 0.3118 18.5861
Panc 02.03 GDSC1; CTRP2 5.832 16.5997 -0.0907 18.8374
SNU-410 CTRP2 7.4647 9.4548 4.3858 0.4032
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 -0.6098 7.3363 -1.8749 40.502
WM278 GDSC1 -4.8256 -2.1892 -4.8395 74.3797
WM115 GDSC1; CTRP2 -4.6686 -3.6274 -4.6686 64.7093
IST-MEL1 GDSC1 -4.6048 4.5478 -6.2326 60.7815
WM35 GDSC1 -4.5374 -2.8809 -4.538 73.1132
RPMI-7951 GDSC1; CTRP2 -4.3211 -2.3817 -4.3211 62.3845
A-431 GDSC1 -4.2073 -1.7836 -4.2214 68.1946
WT2-iPS GDSC1; CTRP2 -4.0836 -3.313 -4.0836 60.8117
WM266-4 CTRP2 -3.987 -2.1468 -3.987 60.1638
SK-MEL-24 GDSC1; CTRP2 -3.8844 -2.1086 -3.8844 59.4821
CHL-1 GDSC1 -3.8193 1.3744 -4.2969 60.0149
MZ-MEL-2 GDSC1 -3.7187 -2.1312 -3.7199 63.2869
DJM-1 GDSC1 -3.4168 -0.9751 -3.4467 59.1092
LOX-IMVI GDSC1; CTRP2 -3.1331 -1.893 -3.1331 54.4797
LB2518-MEL GDSC1 -2.735 0.8918 -2.991 50.9541
Hs 852.T CTRP2; CTRP1 -2.7301 0.839 -2.7567 51.8052
WM793 GDSC1; CTRP2 -2.7015 -0.0521 -2.7054 51.5979
COLO 679 GDSC1 -2.5002 1.0111 -2.7635 48.4768
COLO 792 GDSC1; CTRP2 -2.1493 0.8712 -2.1639 47.9434
VMRC-MELG GDSC1 -1.9361 -1.1208 -1.9362 41.1532
SH-4 GDSC1 -1.9026 6.3086 -4.1737 45.4773
A-375 GDSC1; CTRP2; CTRP1 -1.8571 1.0731 -1.8721 46.0087
M14 GDSC1 -1.198 12.2113 -6.3235 44.3042
Mel JuSo GDSC1; CTRP2 -1.1143 4.1376 -1.4526 41.8092
A-388 GDSC1 -0.9525 3.8317 -2.0986 35.0289
MZ-MEL-7 GDSC1 -0.9148 18.5052 -9.1774 45.2055
Hs 895.T CTRP2 -0.9005 4.875 -1.398 40.7933
CP50-MEL-B GDSC1 -0.6246 10.5009 -4.9563 40.6249
WM88 CTRP2 -0.2254 6.5472 -1.1774 37.6699
RVH-421 GDSC1; CTRP2 -0.0237 10.5077 -2.5522 39.5056
Mel Ho GDSC1; CTRP2 0.6541 7.3787 -0.5384 32.9808
HMV-II GDSC1 0.7506 19.4244 -8.1874 40.3167
CJM [Human melanoma] CTRP2 0.9977 4.6003 0.7409 27.8349
COLO 829 GDSC1; CTRP2 1.1336 11.6843 -1.9124 34.7602
451Lu GDSC1 1.1402 7.8936 -2.0943 25.0668
GAK GDSC1 1.2549 8.1606 -2.1308 24.8092
Hs 294T CTRP2 1.2597 13.6833 -2.7272 35.9413
COLO 783 GDSC1 1.547 10.577 -3.0962 27.8658
G-mel GDSC1 1.6406 9.22 -2.3413 24.4079
IGR-1 GDSC1; CTRP2 1.7348 12.8938 -1.8919 33.0212
HT-144 GDSC1; CTRP2 2.1162 6.8376 1.228 22.7187
A2058 GDSC1; CTRP2 2.3899 11.6795 -0.6809 28.2554
CP66-MEL GDSC1 2.4129 5.9198 -0.1164 8.23
UACC-257 GDSC1; CTRP2 2.4613 11.1291 -0.3495 27.103
WM983B CTRP2 2.7239 12.2093 -0.6174 27.2089
SK-MEL-1 GDSC1; CTRP2; CTRP1 2.7302 10.9845 -0.0213 25.3869
LB373-MEL-D GDSC1 2.7468 5.9164 0.1045 5.7985
K029AX CTRP2 2.8924 13.0931 -0.889 27.5498
Hs 938.T GDSC1 3.2284 8.922 -1.0032 12.1098
HMCB CTRP2 3.2772 11.1672 0.4092 22.5946
WM1552C GDSC1 3.5576 5.2887 0.7863 0.5846
Hs 944.T CTRP2; CTRP1 3.5944 15.7545 -1.5536 27.6788
WM1799 CTRP2 4.1757 15.7378 -1.0424 25.0044
MMAc-SF GDSC1 4.2612 13.3975 -2.4494 17.3362
Hs 936.T CTRP2; CTRP1 4.333 19.2082 -2.6294 28.567
IPC-298 GDSC1; CTRP2 4.5743 20.7499 -3.2035 29.2141
COLO 800 GDSC1; CTRP2 4.8725 24.6454 -4.8997 31.5885
UACC-62 GDSC1; CTRP2 4.9879 11.2817 1.8786 13.3137
SK-MEL-28 GDSC1; CTRP2; CTRP1 5.8765 6.595 4.8051 0.1647
IGR-37 GDSC1; CTRP2 5.8905 20.2196 -1.7359 24.1257
SK-MEL-2 GDSC1; CTRP2 6.0229 7.1498 4.6522 0.4727
SK-MEL-3 GDSC1; CTRP2 6.1806 19.1915 -1.106 21.2406
Hs 839.T CTRP2 6.6583 7.8651 4.6493 0.1888
SK-MEL-5 GDSC1; CTRP2; CTRP1 6.8884 8.1675 4.6288 0.1599
Malme-3M CTRP2 6.9577 17.4485 0.4788 15.7939
COLO 741 CTRP2; CTRP1 7.0137 18.1599 0.0576 16.353
A101D GDSC1; CTRP2 7.096 17.7214 0.3239 15.2842
Hs 688(A).T CTRP2 7.0974 24.1107 -2.7176 24.3115
Hs 940.T GDSC1; CTRP2 7.1277 8.6023 4.7253 0.2489
MeWo GDSC1; CTRP2 7.6309 17.0005 1.0606 11.908
MDA-MB-435S CTRP2 8.0313 18.0656 0.8236 12.1525
IGR-39 CTRP2 8.233 19.0613 0.4824 13.0174
SK-MEL-31 CTRP2 8.5803 18.8695 0.8102 11.4297
SK-MEL-30 GDSC1; CTRP2 9.1246 23.2935 -0.9442 16.1324
G-361 GDSC1; CTRP2; CTRP1 12.8318 30.777 -2.0438 14.5109
EquiPSC Line K2 GDSC1 2.7279 9.7871 -1.7779 18.0557
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-26 GDSC1 -5.8166 1.2541 -6.444 70.7287
OACM5.1 C GDSC1 -5.1466 5.786 -7.2993 61.728
ESO-51 GDSC1 -4.1225 1.7741 -4.742 61.5116
OACP4 C GDSC1 -3.7985 3.022 -4.7984 58.1319
KYAE-1 GDSC1 -3.7474 5.685 -5.7896 55.9723
KYSE-220 GDSC1 -1.2527 5.001 -2.9253 39.5923
SK-GT-4 GDSC1 -1.0357 5.1071 -2.7557 37.8656
KYSE-50 GDSC1 -0.5268 5.8379 -2.5978 34.6094
FLO-1 GDSC1 -0.2473 7.6502 -3.21 35.2684
HCE-4 GDSC1 3.4397 6.1526 0.3911 2.6151
TE-12 GDSC1 4.1402 14.473 -3.0519 20.2307
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 -1.2768 6.4923 -2.2976 43.8216
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-N-SI9s CTRP2 -4.6944 -2.7846 -4.6944 64.8677
SJNB-13 GDSC1 -4.3131 2.7802 -5.271 61.3168
SK-N-MC-IXC GDSC1 -4.1565 -3.3086 -4.1565 68.9007
GI-ME-N GDSC1 -3.9132 -2.0074 -3.9172 65.4364
TGW GDSC1 -3.7766 1.8823 -4.3975 59.1291
NH-12 GDSC1 -3.4847 -1.1156 -3.5086 59.9597
NB(TU)1 GDSC1 -3.4539 -1.4201 -3.4641 59.8261
KP-N-YS GDSC1 -3.2445 3.5442 -4.395 54.2697
IMR-5 GDSC1 -2.9104 10.8575 -7.2922 51.0287
MHH-NB-11 GDSC1; CTRP2 -2.5095 2.0862 -2.6195 50.3074
IMR-32 CTRP2 -2.0253 3.9785 -2.4083 47.4503
NB1 GDSC1; CTRP2 -1.9893 1.8148 -2.0479 46.9419
SJNB-10 GDSC1 -1.7608 1.6556 -2.1317 40.5951
NH-6 CTRP2 -1.732 3.4622 -1.9868 45.5406
SK-N-SH GDSC1; CTRP2 -1.5452 2.1607 -1.6116 44.0482
SiMa GDSC1; CTRP2 -1.4707 2.7472 -1.5954 43.6744
SJNB-14 GDSC1 -1.4566 28.8289 -14.7894 47.8629
SJNB-7 GDSC1 -1.3702 3.0055 -2.1892 38.0185
SK-N-FI GDSC1; CTRP2 -1.129 3.1694 -1.289 41.5301
NB69 GDSC1 -1.0627 4.3148 -2.4245 36.9376
SK-N-DZ GDSC1; CTRP2 -0.7223 4.8122 -1.1872 39.6162
CHP-134 GDSC1 0.3211 9.2788 -3.4977 33.7173
LA-N-6 GDSC1 0.326 6.5372 -2.1361 28.6334
Kelly GDSC1; CTRP2 0.6144 10.8097 -2.0346 36.57
SJNB-17 GDSC1 0.623 8.585 -2.8861 30.4899
CHP-212 GDSC1; CTRP2 0.7004 1.8204 0.7002 28.9412
GOTO GDSC1 0.7081 9.852 -3.4432 32.0573
KP-N-YN GDSC1 0.7292 6.2413 -1.6268 24.2817
SK-N-AS GDSC1; CTRP2 1.0673 10.815 -1.5796 34.2479
CHP-126 GDSC1; CTRP2 1.1708 10.7256 -1.4349 33.6122
SJNB-5 GDSC1 1.6312 5.2717 -0.3774 12.5682
SJNB-6 GDSC1 1.7572 8.8585 -2.0663 22.6776
SJNB-12 GDSC1 1.795 6.2216 -0.7212 14.4823
SK-N-BE(2)-M17 GDSC1 2.1557 7.082 -0.8708 14.3241
SK-N-BE(2) CTRP2 5.1104 17.2786 -0.9078 23.4562
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 -3.7855 -0.5568 -3.7927 58.7052
SNU-308 CTRP2 -1.8566 3.4505 -2.1193 46.3233
SNU-1196 CTRP2 2.9952 12.4923 -0.5001 26.1863
SNU-1079 CTRP2 4.4617 19.2205 -2.5349 29.2657
HuCC-T1 GDSC1; CTRP2 6.7143 33.6281 -7.8807 32.5767
HuH-28 CTRP2 6.971 15.1398 1.4983 11.3139
SNU-869 CTRP2 10.8862 25.6984 -0.9145 13.7689
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 GDSC1; CTRP2 -5.1138 -4.2003 -5.1138 67.6754
MDA-MB-453 GDSC1; CTRP2 -4.5345 -1.6415 -4.5361 64.6463
OCUB-M GDSC1 -4.4788 -3.1304 -4.4789 72.7151
HCC1599 GDSC1 -4.2244 2.8158 -5.187 60.7941
MDA-MB-361 GDSC1; CTRP2 -2.9761 0.1567 -2.9852 68.2105
CAL-148 GDSC1; CTRP2 -2.7729 0.2856 -2.783 52.061
HMC-1-8 CTRP2 -2.6881 1.1696 -2.7305 51.4732
HCC1806 GDSC1; CTRP2 -2.347 2.633 -2.5145 49.296
COLO 824 GDSC1 -2.1931 4.4848 -3.6632 46.7523
HCC38 GDSC1; CTRP2 -1.2963 4.4248 -1.7165 43.0886
MRK-nu-1 GDSC1 -1.2856 5.9253 -3.3821 40.8609
HCC1143 CTRP2 -1.2407 4.1609 -1.5953 42.6316
CAL-85-1 GDSC1; CTRP2 -0.7264 6.099 -1.5701 40.4157
MDA-MB-175-VII GDSC1 -0.3049 8.3999 -3.6304 36.6806
HCC1954 GDSC1; CTRP2 -0.2797 5.6989 -0.957 37.3578
Evsa-T GDSC1 -0.1561 4.6687 -1.683 28.6789
MDA-MB-330 GDSC1 -0.0922 8.9566 -3.7096 35.9802
MDA-MB-468 GDSC1; CTRP2 0.1377 7.5558 -1.1575 36.314
MDA-MB-231 GDSC1; CTRP2 0.167 5.5473 -0.4238 34.322
BT-474 GDSC1; CTRP2 0.4388 12.0534 -2.7008 38.9816
SK-BR-3 CTRP2 0.4555 19.0152 -5.9679 42.3737
HCC2218 GDSC1 0.5089 12.5177 -4.9455 36.5166
ZR-75-1 CTRP2 0.5955 10.3703 -1.8576 36.2848
HCC70 GDSC1 0.7004 11.1374 -4.0912 33.9275
CAL-51 GDSC1; CTRP2 0.7349 3.9381 0.5906 29.1967
ZR-75-30 GDSC1; CTRP2 0.869 18.3318 -5.3346 40.3545
MFM-223 GDSC1 1.0428 7.482 -1.9717 24.8352
EFM-192A GDSC1; CTRP2 1.4357 10.8917 -1.2459 32.3851
YMB-1-E GDSC1 1.5593 7.6171 -1.6067 20.9262
MDA-MB-436 GDSC1 1.7611 9.212 -2.2396 23.5123
HCC1419 GDSC1; CTRP2 1.8686 9.7009 -0.2672 28.4786
T-47D GDSC1; CTRP2 1.8766 12.9169 -1.6818 32.9431
HCC1187 GDSC1 2.049 15.3898 -5.092 32.1416
HCC1500 GDSC1; CTRP2 2.1935 9.54 0.132 26.323
HCC1569 GDSC1; CTRP2 2.3119 10.3894 -0.1453 26.8792
AU565 GDSC1; CTRP2 2.3215 16.6329 -3.0573 34.4454
UACC-893 GDSC1 2.3659 11.7587 -3.0295 24.9711
EFM-19 GDSC1 2.487 6.7796 -0.4807 10.6411
MDA-MB-415 GDSC1; CTRP2 2.5524 7.7075 1.3854 21.9476
HCC202 GDSC1; CTRP2 3.1897 13.2957 -0.7132 26.3303
HCC2157 GDSC1 3.2835 4.8878 0.8244 0.6294
HDQ-P1 GDSC1; CTRP2 3.4385 13.3581 -0.5165 25.1645
UACC-812 GDSC1 3.5997 5.3573 0.7778 0.5875
HCC1937 GDSC1; CTRP2 3.8674 20.1448 -3.5077 31.1934
BT-483 GDSC1 3.9523 13.0264 -2.4826 18.2423
Hs 578T GDSC1; CTRP2 4.0599 9.3437 2.0277 14.6708
MCF-7 GDSC1; CTRP2; CTRP1 4.1302 9.5384 1.9964 14.6394
MDA-MB-157 GDSC1; CTRP2 4.1359 12.3716 0.6986 20.5079
JIMT-1 GDSC1; CTRP2 4.6501 11.3566 1.554 15.2821
KPL-1 CTRP2 6.0944 7.3413 4.6081 0.5521
BT-20 GDSC1; CTRP2 6.4394 15.5509 0.9036 14.3675
CAMA-1 GDSC1; CTRP2 6.5519 17.4167 0.0653 17.0472
Hs 578Bst CTRP2 6.8587 8.3392 4.7139 0.3717
CAL-120 GDSC1; CTRP2 6.9268 8.3553 4.576 0.233
HCC1395 GDSC1; CTRP2 7.6078 17.5336 0.7857 12.9084
BT-549 GDSC1; CTRP2 7.783 15.5048 1.8827 8.6907
HCC1428 GDSC1; CTRP2 11.4957 27.2344 -1.2454 13.9441
BT 239 CTRP2 -5.8443 -2.6226 -5.8459 72.8882
BT 271 CTRP2 -4.4625 -1.1646 -4.4672 64.0577
BT 112 CTRP2 -4.4171 -1.9298 -4.4176 62.9799
BT 145 CTRP2 -4.0373 -1.3034 -4.039 60.4389
BT 286 CTRP2 -3.7641 -1.9567 -3.7641 59.6701
BT 139 CTRP2 -3.7243 -2.084 -3.7244 59.4079
BT 504 CTRP2 -3.687 -1.8564 -3.687 59.1572
BT 428 CTRP2 -3.5319 -1.7206 -3.532 58.1272
BT 172 CTRP2 -3.5118 -1.949 -3.5118 57.995
BT 330 CTRP2 -3.3845 -0.0932 -3.3941 57.0472
BT 232 CTRP2 -3.3462 -1.5761 -3.3462 56.8928
BT 444 CTRP2 -3.3312 -0.0952 -3.3401 56.7064
BT 416 CTRP2 -3.2888 -1.7132 -3.2888 56.5122
BT147 CTRP2 -3.1521 1.5569 -3.237 55.2703
BT 131 CTRP2 -2.7936 -0.2933 -2.7956 53.2108
BT 228 CTRP2 -2.4885 4.2477 -2.9499 51.0023
BT 216 CTRP2 -2.4498 0.3756 -2.4565 50.9285
BT 328 CTRP2 -2.4477 -0.3857 -2.4483 50.9193
BT 440 CTRP2 -2.4286 0.4592 -2.4364 50.7874
BT164 CTRP2 -2.2252 6.3428 -3.2782 48.8308
BT 245 CTRP2 -1.9121 4.5513 -2.3932 47.7397
BT 482 CTRP2 -1.4889 2.4339 -1.5709 44.7088
BT 224 CTRP2 -1.473 1.9599 -1.5205 43.5342
BT 187 CTRP2 -1.0743 6.2879 -1.9704 43.3877
BT 340 CTRP2 -0.9813 5.1355 -1.5266 42.3141
BT 248 CTRP2 -0.8043 4.2823 -1.1256 40.7875
BT 179 CTRP2 -0.4714 7.7384 -1.8777 39.9821
BT 231 CTRP2 -0.1299 14.0032 -4.163 42.43
BT 159 CTRP2 0.3582 6.5693 -0.51 34.8633
BT 333 CTRP2 1.3865 8.8367 -0.3068 30.9377
BT 359 CTRP2 2.5695 14.9336 -1.9964 31.8155
BT 320 CTRP2 4.0397 12.7548 0.4225 21.6705
BT 498 CTRP2 6.5311 18.5075 -0.3728 19.237
BT 422 CTRP2 7.8458 18.4884 0.6182 13.9113
⏷ Show the Full List of 91 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 -3.2131 -1.0697 -3.2135 55.0076
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GI-1 GDSC1 -4.4265 -1.5753 -4.4563 69.7708
KS-1 [Human Krukenberg tumour] GDSC1 -4.1132 -2.7935 -4.1133 68.2572
M059J GDSC1 -3.9865 -1.6255 -4.0013 65.7887
MOG-G-CCM GDSC1 -3.8426 1.6611 -4.4036 59.832
KINGS-1 GDSC1 -3.8032 -0.1401 -3.9477 61.9305
AM-38 GDSC1; CTRP2 -3.5879 -0.1123 -3.6013 57.369
PFSK-1 GDSC1 -3.5638 0.1764 -3.7432 59.4233
Daoy GDSC1; CTRP2 -3.4525 -1.6298 -3.4525 56.6053
SNU-466 CTRP2 -3.1876 -0.8848 -3.1884 54.8345
D-566MG GDSC1 -3.0463 0.1876 -3.1872 54.4013
SF126 GDSC1; CTRP2 -2.9501 -1.7585 -2.9501 53.2603
D-247MG GDSC1 -2.8493 -1.5035 -2.8506 52.5606
LN-18 GDSC1; CTRP2 -2.6412 -1.3995 -2.6412 51.2026
KNS-60 CTRP2 -2.6031 0.5233 -2.6162 50.939
SF295 GDSC1; CTRP2; CTRP1 -2.5844 0.8107 -2.6062 50.8579
GaMG GDSC1; CTRP2; CTRP1 -2.4696 2.1686 -2.5856 50.1015
Onda 11 GDSC1 -2.4093 3.6056 -3.5291 48.1725
U-251MG GDSC1; CTRP2 -2.3973 1.3774 -2.4378 50.5697
Becker GDSC1; CTRP2 -2.3817 1.7327 -2.4514 49.4928
D-336MG GDSC1 -2.3133 3.4528 -3.3669 47.3478
H4 GDSC1 -2.2863 0.5912 -2.4393 45.9378
SK-MG-1 GDSC1 -2.2272 1.1292 -2.4949 45.5071
8-MG-BA GDSC1; CTRP2 -2.2254 0.826 -2.2401 48.4467
Hs 683 GDSC1; CTRP2 -2.1295 0.3241 -2.1331 47.7987
YH-13 GDSC1; CTRP2 -2.0794 1.1679 -2.103 47.4913
M059K CTRP2 -1.9189 1.6216 -1.9611 46.4595
42-MG-BA GDSC1; CTRP2 -1.8335 3.6775 -2.1192 47.1376
GB-1 GDSC1; CTRP2 -1.8305 0.9252 -1.8409 45.8233
U-118MG GDSC1; CTRP2 -1.8266 3.3481 -2.0684 46.1144
D-423MG GDSC1 -1.6908 4.3025 -3.0642 42.5998
T98G GDSC1; CTRP2 -1.186 2.276 -1.2453 41.6676
TM-31 CTRP2 -1.0615 3.2043 -1.2219 41.0925
CCF-STTG1 CTRP2 -0.9634 1.687 -0.9798 40.0751
SF539 GDSC1; CTRP2 -0.9302 2.7684 -1.0158 41.06
YKG-1 GDSC1; CTRP2 -0.769 5.0714 -1.3074 40.0658
SW1088 GDSC1; CTRP2 -0.5731 3.7095 -0.78 38.0275
D-392MG GDSC1 -0.4231 5.3503 -2.2655 32.792
GMS-10 CTRP2 -0.2723 12.3561 -3.6282 41.7041
LNZTA3WT4 GDSC1 -0.2021 4.2925 -1.551 28.2002
ONS-76 GDSC1; CTRP2 -0.1713 4.801 -0.5831 35.9842
SNU-201 CTRP2 -0.0299 7.2643 -1.2259 39.3159
SF268 GDSC1; CTRP2 -0.0138 9.7338 -2.1435 39.593
MOG-G-UVW GDSC1 0.0606 5.1912 -1.725 27.8302
D-263MG GDSC1 0.434 3.1011 -0.3677 17.3057
U-87MG ATCC GDSC1; CTRP2 0.4926 7.8247 -0.8854 34.4381
KALS-1 GDSC1; CTRP2 0.8967 11.6735 -2.1432 35.9172
DK-MG GDSC1; CTRP2 1.1289 10.2836 -1.277 33.3693
D-542MG GDSC1 1.1299 9.2782 -2.7949 28.1925
LN-405 GDSC1 1.4509 7.8782 -1.8263 22.5292
D283 Med GDSC1; CTRP2 1.8013 3.7714 1.7543 21.7645
A-172 GDSC1; CTRP2 1.8373 8.8174 0.0983 27.4329
LN-229 GDSC1; CTRP2; CTRP1 1.9862 9.8521 -0.2184 27.9995
CAS-1 GDSC1; CTRP2 2.3316 8.24 0.8588 23.4585
DBTRG-05MG GDSC1; CTRP2 2.7229 14.0506 -1.5145 29.5908
SNB-75 GDSC1; CTRP2 2.863 8.2914 1.4473 20.88
SNU-626 CTRP2 2.9676 10.0296 0.6634 22.4792
SNU-738 CTRP2 3.0125 12.2567 -0.3691 25.7527
D-502MG GDSC1 3.0898 10.0962 -1.6669 16.4081
Onda 10 GDSC1 3.1239 9.4197 -1.3143 14.2898
KNS-81-FD GDSC1 3.3539 14.9804 -3.8712 25.2217
GOS-3 CTRP2 3.6186 12.258 0.1899 22.5201
KG-1-C CTRP2 4.643 15.9845 -0.6571 23.7082
SNU-489 CTRP2 4.6629 16.0761 -0.7925 23.27
SNU-1105 CTRP2 6.0117 14.5294 1.082 14.464
KNS-81 CTRP2 6.0784 11.2447 2.7581 7.7724
KNS-42 GDSC1; CTRP2 6.8236 20.3507 -1.1812 20.3309
NMC-G1 GDSC1; CTRP2 6.9892 8.3707 4.5945 0.1858
SW1783 GDSC1; CTRP2 7.2494 14.3218 2.0898 8.6512
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 -3.9706 1.6795 -4.5486 60.667
TGBC24TKB GDSC1 2.8499 9.2879 -1.4442 15.8213
TGBC1TKB GDSC1 3.4364 9.5824 -1.1792 12.6588
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2; CTRP1 -3.4622 -1.3745 -3.4628 53.7168
JHUEM-1 CTRP2 -3.1305 1.3995 -3.2073 54.2304
HEC-265 CTRP2; CTRP1 -3.0433 -1.9882 -3.0433 53.926
JHUEM-7 CTRP2 -2.8237 1.3388 -2.8823 52.3274
HEC-151 CTRP2; CTRP1 -2.29 0.7786 -2.3045 48.8732
MFE-280 GDSC1 -0.6304 4.8451 -2.2315 33.7478
HEC-6 CTRP2; CTRP1 -0.2086 9.8237 -2.442 40.0015
AN3-CA GDSC1; CTRP2 0.0384 5.58 -0.574 35.1989
HEC-50B CTRP2 0.1975 10.841 -2.4726 38.6606
HEC-59 CTRP2; CTRP1 0.8466 7.6926 -0.4529 32.1727
JHUEM-3 CTRP2 0.9817 8.2722 -0.5525 31.9613
MFE-296 GDSC1; CTRP2 1.0447 7.9026 -0.2758 31.9192
KLE GDSC1; CTRP2; CTRP1 1.2407 7.8211 -0.089 29.8581
HEC-1-A CTRP2 1.3139 11.2445 -1.4535 34.0424
RL95-2 GDSC1; CTRP2 1.5596 11.2957 -1.3099 32.183
MFE-319 GDSC1; CTRP2; CTRP1 1.624 8.4055 0.065 28.2228
HEC-1-B CTRP2 1.7174 10.9078 -0.9734 30.8896
HEC-251 CTRP2; CTRP1 2.1839 10.1692 -0.1616 27.3389
ESS-1 GDSC1; CTRP2 3.5572 7.9102 2.2402 14.9968
EFE-184 CTRP2 5.5014 17.1417 -0.6278 21.1201
HEC-108 CTRP2; CTRP1 5.6179 17.4955 -0.7 21.167
EN GDSC1; CTRP2 6.0907 18.2721 -0.719 20.2944
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 -2.8288 -0.8328 -2.8291 52.4968
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-140 GDSC1 -4.3009 -1.856 -4.3146 69.2005
786-O GDSC1; CTRP2 -3.0524 -0.0252 -3.0601 53.9075
RXF 393L GDSC1 -2.7836 4.0595 -4.1068 50.9892
LB996-RCC GDSC1 -2.2244 -0.2357 -2.2584 44.8864
LB1047-RCC GDSC1 -2.214 2.3066 -2.8356 45.979
BB65-RCC GDSC1 -2.1001 1.4194 -2.4332 44.252
KTCTL-21 GDSC1 -1.8167 3.252 -2.7605 42.8037
TK-10 GDSC1 -0.509 11.5907 -5.388 40.814
KTCTL-26A GDSC1 -0.3197 5.6325 -2.3002 32.4097
TUHR4TKB CTRP2 -0.2652 7.029 -1.3918 38.2836
KTCTL-1M GDSC1 0.2184 7.7019 -2.8085 31.8825
A-704 GDSC1 0.555 4.8842 -1.1132 21.9547
NCC021 GDSC1 1.4919 5.1889 -0.4483 13.5806
BFTC-909 GDSC1; CTRP2 1.5773 8.7202 -0.1254 28.8916
HA7-RCC GDSC1 1.8037 8.5427 -1.8713 21.5125
UO-31 GDSC1; CTRP2 2.022 9.3471 0.1208 27.7823
KTCTL-195 GDSC1 2.1512 8.3919 -1.5231 18.4172
KMRC-1 GDSC1; CTRP2 2.3272 9.1511 0.4439 24.921
VMRC-RCW GDSC1; CTRP2; CTRP1 2.8464 9.0937 0.9939 21.6699
SW156 GDSC1 2.9014 8.4186 -0.9849 12.8675
SN12C GDSC1 3.1113 9.9169 -1.5644 15.7751
OS-RC-2 GDSC1; CTRP2 3.2338 14.8628 -1.4448 28.1869
KTCTL-13 GDSC1 3.6912 5.7818 0.6566 0.9803
SW13 GDSC1 3.8613 5.8644 0.6955 0.7075
LB2241-RCC GDSC1 3.9591 6.4289 0.5229 1.3213
CAL-54 GDSC1; CTRP2 4.6805 15.1144 -0.297 21.7485
769-P GDSC1; CTRP2 4.9597 15.1689 -0.0886 20.5178
ACHN GDSC1; CTRP2 5.0603 15.4427 -0.1415 20.4847
KMRC-2 CTRP2 5.6229 13.464 1.3064 14.3311
A-498 GDSC1; CTRP2 5.8415 10.7715 2.815 7.9277
TUHR10TKB CTRP2 5.9673 10.9782 2.8071 7.7518
KMRC-20 GDSC1; CTRP2 6.2161 13.0915 1.9507 10.7919
VMRC-RCZ GDSC1; CTRP2 6.3943 17.1888 0.0572 17.347
KMRC-3 CTRP2 6.4923 16.2933 0.697 15.8463
RCC10RGB GDSC1; CTRP2; CTRP1 7.0728 8.2778 4.8202 0.12
SNU-1272 CTRP2 7.8252 13.5469 2.8264 5.1069
Caki-1 GDSC1; CTRP2 7.8727 13.9719 2.6597 5.67
Caki-2 CTRP2 10.6087 19.2884 1.8507 5.6127
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 61 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW403 CTRP1 -7.887 10.5061 -10.8576 75.2816
SW48 GDSC1; CTRP2; CTRP1 -5.1132 -3.7672 -5.1132 67.7013
SNU-175 GDSC1; CTRP2; CTRP1 -4.6573 -2.3308 -4.6575 64.5882
RKO GDSC1; CTRP2; CTRP1 -4.2398 -2.471 -4.2398 61.848
CL-34 CTRP2; CTRP1 -4.0466 1.7934 -4.215 59.3216
SK-CO-1 CTRP2; CTRP1 -3.8467 -2.1314 -3.8467 59.2712
SW620 GDSC1; CTRP2; CTRP1 -3.5278 -0.1246 -3.54 56.9896
GP2d CTRP2; CTRP1 -3.5004 -0.64 -3.5041 56.9204
SNU-C2B GDSC1 -3.4067 3.5327 -4.5642 55.3248
COLO201 CTRP2 -3.375 0.0678 -3.3894 55.9848
MDST8 GDSC1; CTRP2; CTRP1 -3.3426 -0.8968 -3.3438 55.8601
LS411N GDSC1; CTRP2; CTRP1 -3.3161 -0.0099 -3.3276 55.6602
LS513 GDSC1; CTRP2; CTRP1 -3.2985 -2.1835 -3.2985 55.6247
GP5d GDSC1 -3.0222 -0.7303 -3.053 54.5246
COLO205 GDSC1; CTRP2; CTRP1 -3.0167 4.4072 -3.5852 53.0141
CaR-1 GDSC1 -2.8274 -0.2326 -2.8939 52.1442
CL-40 CTRP1 -2.6349 -1.3752 -2.9039 12.023
SNU-1033 CTRP2 -2.4947 10.0139 -4.8663 50.7128
CCK-81 GDSC1; CTRP2 -2.4502 2.4188 -2.5959 49.9346
T84 GDSC1; CTRP2 -2.0525 2.3107 -2.1525 48.3678
SW480 CTRP1 -1.9592 0.5756 -3.2161 11.4975
HCT 15 GDSC1; CTRP2 -1.739 2.5652 -1.8581 45.4006
NCI-H747 GDSC1; CTRP2 -1.7069 4.2154 -2.0922 46.4605
COLO 320HSR GDSC1 -1.5497 3.9637 -2.7729 41.0206
COLO 320 CTRP2; CTRP1 -1.4619 3.4704 -1.6807 44.7543
SNU-407 GDSC1; CTRP2 -1.3798 4.339 -1.7873 43.5808
NCI-H508 CTRP2; CTRP1 -1.1687 5.5433 -1.8787 42.7831
SNU-61 GDSC1; CTRP2; CTRP1 -0.943 4.6025 -1.3746 40.9235
SW837 GDSC1 -0.7745 8.413 -4.0743 39.7413
SW626 GDSC1 -0.6089 6.2926 -2.8939 36.0217
KM12 GDSC1; CTRP2; CTRP1 -0.5912 5.5227 -1.2429 39.2156
SW948 GDSC1; CTRP2; CTRP1 -0.4646 6.0014 -1.2539 38.7452
SNU-C4 CTRP2; CTRP1 -0.4392 4.3272 -0.7386 38.4038
SNU-C1 GDSC1; CTRP2 -0.3606 5.7114 -1.049 37.8837
HCC2998 GDSC1 -0.3073 4.2119 -1.6175 29.11
LS180 GDSC1; CTRP2; CTRP1 -0.0155 4.8948 -0.4375 35.0096
C2BBe1 GDSC1; CTRP2; CTRP1 0.0539 9.6849 -2.1104 38.5693
LoVo GDSC1; CTRP2; CTRP1 0.103 6.4643 -0.7934 35.5499
NCI-H716 GDSC1; CTRP2 0.7516 37.8457 -15.0581 45.3333
LS1034 GDSC1; CTRP2 0.7985 6.5507 -0.0731 31.1473
CW-2 GDSC1; CTRP2; CTRP1 0.8996 9.4653 -1.1477 33.7656
HT-55 GDSC1; CTRP2; CTRP1 1.1735 7.681 -0.1077 30.0607
HCT 8 CTRP2; CTRP1 1.432 7.3181 0.3669 28.7465
SNU-C5 GDSC1; CTRP2; CTRP1 1.4683 9.4643 -0.5653 30.5075
LS123 GDSC1; CTRP2; CTRP1 1.8483 9.9143 -0.3849 28.8866
CL-11 GDSC1; CTRP2 1.8593 8.1535 0.4111 26.3418
SNU-C2A CTRP2; CTRP1 1.9039 12.761 -1.6581 32.0939
HT115 GDSC1; CTRP2; CTRP1 1.9311 6.9871 0.9722 24.1789
SW1463 GDSC1 2.1558 7.2314 -0.9446 14.814
SW1417 GDSC1; CTRP2 2.4345 10.0843 0.1182 25.7145
SNU-1040 GDSC1; CTRP1 2.7645 10.7212 -2.2108 16.8345
DLD-1 CTRP2; CTRP1 2.8527 9.1715 0.9638 21.7632
OUMS-23 CTRP2 2.8956 10.4718 0.3828 23.6334
RCM-1 [Human ESC] GDSC1; CTRP2; CTRP1 3.9115 13.3765 -0.0998 22.791
SW1116 GDSC1; CTRP2 4.221 9.7641 1.9675 18.4801
SNU-81 GDSC1; CTRP2; CTRP1 4.2921 11.2097 1.3143 16.9688
COLO 678 GDSC1; CTRP2; CTRP1 5.1441 14.8686 0.2152 19.1525
SNU-503 CTRP2 5.2466 14.9974 0.2353 18.8831
HCC-56 CTRP2 5.8178 19.5115 -1.5551 23.1086
HT-29 GDSC1; CTRP2; CTRP1 6.5742 7.8616 4.6171 0.2768
HCT 116 GDSC1; CTRP2; CTRP1 7.9087 16.3155 1.5801 9.6351
⏷ Show the Full List of 61 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 -4.9505 -3.1205 -4.9514 77.5578
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hep-G2 CTRP2; CTRP1 -4.9449 -2.7847 -4.945 66.5109
SNU-886 CTRP2 -4.425 1.5763 -4.5904 61.3974
HLE GDSC1 -3.7427 -0.5809 -3.8236 61.9998
PLC/PRF/5 CTRP2 -3.1069 -1.1247 -3.1071 54.3027
JHH-2 GDSC1; CTRP2 -3.0902 0.936 -3.133 54.0541
Hep 3B2.1-7 GDSC1; CTRP2 -3.0199 0.4095 -3.0376 53.6636
SNU-387 GDSC1; CTRP2 -2.9936 0.3286 -3.0084 53.5001
Hep-G2/C3A GDSC1 -2.5952 -1.2586 -2.5971 49.3937
SNU-423 GDSC1; CTRP2 -2.5921 -0.404 -2.5931 50.8747
SNU-878 CTRP2 -2.3572 1.1115 -2.386 49.3226
Li-7 CTRP2 -2.0168 2.6436 -2.1636 47.2107
JHH-7 GDSC1 0.3717 6.2161 -1.9362 27.4679
JHH-5 CTRP2 0.8492 9.8611 -1.3731 34.4531
HuH-6 CTRP2 0.9285 9.7497 -1.2428 33.9029
HLF CTRP2 1.9367 10.9118 -0.7588 29.6998
Huh-7 GDSC1 2.0325 12.066 -3.4461 27.5385
HuH-1 GDSC1; CTRP2 2.6005 10.5988 0.0375 25.5355
JHH-4 GDSC1; CTRP2 2.864 11.1517 0.0262 24.8928
SNU-449 GDSC1; CTRP2; CTRP1 3.1737 8.3388 1.6687 18.2859
JHH-1 GDSC1; CTRP2 3.7467 16.2404 -1.6687 27.5733
SNU-182 CTRP2 3.7692 16.0168 -1.5377 27.1981
SNU-398 GDSC1; CTRP2; CTRP1 5.5658 17.4353 -0.7221 21.276
SNU-761 CTRP2 5.7952 18.7331 -1.1848 22.1601
SNU-475 GDSC1; CTRP2 6.1979 7.6419 4.5344 0.6981
JHH-6 GDSC1; CTRP2; CTRP1 6.655 7.4355 4.8107 0.0263
SK-HEP-1 GDSC1; CTRP2 8.758 22.5018 -0.8166 16.2866
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 217 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SBC-3 GDSC1 -6.3256 -5.0773 -6.3256 92.8135
NCI-H847 GDSC1 -5.527 7.1334 -8.2556 61.8117
NCI-H3122 GDSC1 -5.2557 6.1815 -7.5755 61.7481
NCI-H146 CTRP2 -5.0856 -3.1557 -5.0856 67.4651
Lu-134-A GDSC1 -4.7271 -2.8337 -4.7285 74.9433
NCI-H1048 GDSC1; CTRP1 -4.6846 1.325 -4.8356 74.615
NCI-H1184 CTRP2 -4.629 -2.6001 -4.629 64.4265
HCC44 GDSC1; CTRP2; CTRP1 -4.1263 -0.6628 -4.1355 60.9097
NCI-H64 GDSC1 -4.1117 -3.2113 -4.1117 68.3372
Ms-1 GDSC1 -4.0597 3.532 -5.2643 59.1423
NCI-H1341 CTRP2 -4.0507 7.6937 -5.713 56.3858
NCI-H1770 GDSC1 -3.9772 -1.9236 -3.9834 66.0502
PC-14 GDSC1; CTRP2 -3.9477 2.7537 -4.2518 58.3002
Lu-99 CTRP2; CTRP1 -3.7415 -1.9374 -3.7415 58.5703
NCI-H2135 GDSC1 -3.6556 0.74 -3.9582 59.5444
HOP-62 GDSC1; CTRP2 -3.5218 2.3315 -3.7155 57.1309
NCI-H1915 GDSC1; CTRP2; CTRP1 -3.4861 -1.1756 -3.4867 56.8601
HCC2108 CTRP2; CTRP1 -3.4528 -1.8363 -3.4529 56.6092
NCI-H650 GDSC1; CTRP2; CTRP1 -3.4311 -1.7573 -3.4311 56.5061
NCI-H211 GDSC1; CTRP2 -3.362 4.1435 -3.9004 54.7937
Lu-65 GDSC1; CTRP2; CTRP1 -3.316 2.8593 -3.588 54.9899
DV-90 CTRP2; CTRP1 -3.2278 6.5056 -4.4174 53.5511
HCC1588 CTRP2 -3.1265 -1.922 -3.1265 54.4354
NCI-H1944 GDSC1; CTRP2; CTRP1 -3.1228 9.6837 -5.4523 52.528
EMC-BAC-2 GDSC1 -3.0933 -0.8832 -3.1171 55.4043
KNS-62 CTRP2; CTRP1 -2.9372 -0.343 -2.9396 54.1599
NCI-H596 GDSC1; CTRP1 -2.8172 -0.5525 -2.8525 40.6665
EPLC-272H GDSC1; CTRP2; CTRP1 -2.8064 2.8367 -3.0361 52.1094
NCI-H1155 GDSC1; CTRP2 -2.69 0.9564 -2.7211 51.4946
HCC2935 CTRP2; CTRP1 -2.6139 6.7117 -3.7813 51.4358
NCI-H2369 GDSC1 -2.5253 -0.7089 -2.5403 48.5418
NCI-H292 GDSC1; CTRP2 -2.4705 3.2846 -2.7521 50.0584
DMS 114 GDSC1; CTRP2 -2.3624 2.152 -2.463 50.335
LXF 289 GDSC1; CTRP2; CTRP1 -2.2573 1.2168 -2.2879 48.7167
Lu-135 GDSC1 -2.2037 6.2495 -4.4497 47.3745
NCI-H2073 CTRP1 -2.1579 -0.3033 -2.9485 9.9838
NCI-H2286 CTRP2; CTRP1 -1.9652 1.3966 -1.9959 46.7984
HCC1359 CTRP1 -1.9626 -0.6764 -2.593 5.9344
LC-2/ad GDSC1 -1.9613 10.5381 -6.2258 47.1211
HOP-92 GDSC1; CTRP2 -1.9189 1.2069 -1.9377 59.7918
LCLC-97TM1 GDSC1; CTRP2; CTRP1 -1.9118 7.8007 -3.4406 47.5108
COR-L51 CTRP1 -1.8963 3.2222 -4.487 21.1544
NCI-H1339 CTRP2 -1.8956 1.86 -1.9535 46.3289
NCI-H446 GDSC1; CTRP2 -1.8594 9.2544 -3.9466 47.4768
COR-L321 GDSC1 -1.8196 2.7518 -2.5705 42.3704
RERF-LC-MS GDSC1; CTRP2 -1.7097 0.9273 -1.7184 45.0176
COR-L105 GDSC1; CTRP2 -1.6625 3.443 -1.9082 45.0939
COR-L279 CTRP1 -1.6557 22.9522 -9.955 57.07
SW1271 GDSC1; CTRP2 -1.6471 3.6955 -1.9391 45.0609
NCI-H1299 GDSC1; CTRP2; CTRP1 -1.5893 1.8312 -1.6322 44.3444
SHP-77 GDSC1; CTRP2; CTRP1 -1.504 3.3292 -1.7161 44.0944
NCI-H647 GDSC1; CTRP2 -1.4972 5.823 -2.3215 44.8146
HCC1438 CTRP2 -1.4871 2.8638 -1.6173 44.7781
EBC-1 GDSC1; CTRP2; CTRP1 -1.4604 8.3178 -3.1512 45.4628
COLO 668 GDSC1; CTRP2; CTRP1 -1.4586 4.6835 -1.955 44.2372
COR-L303 GDSC1 -1.4018 3.5945 -2.463 39.172
COR-L311 GDSC1 -1.2752 2.955 -2.0684 36.9201
NCI-H2030 GDSC1; CTRP2; CTRP1 -1.2502 4.4867 -1.8514 39.5953
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2; CTRP1 -1.2283 5.3877 -1.895 43.1154
NCI-H2227 GDSC1 -1.2145 6.6253 -3.6393 41.0062
Lu-99A GDSC1 -1.1622 4.8391 -2.7607 38.6058
NCI-H2795 GDSC1 -1.146 3.2445 -2.0495 36.011
NCI-H2171 GDSC1; CTRP2 -1.0866 6.9454 -2.2475 42.9615
HCC1195 CTRP2; CTRP1 -1.0785 4.0597 -1.3969 41.5436
COR-L23 GDSC1; CTRP1 -1.0249 3.5129 -2.0358 28.1913
Calu-6 GDSC1; CTRP2; CTRP1 -0.9774 4.3848 -1.3576 41.0869
NCI-H23 GDSC1; CTRP2; CTRP1 -0.9725 3.5602 -1.1831 40.6876
NCI-H1755 GDSC1; CTRP2; CTRP1 -0.9585 3.4257 -1.1464 40.4879
RERF-LC-A1 CTRP2 -0.9413 4.9011 -1.4494 41.0658
NCI-H2110 GDSC1; CTRP2; CTRP1 -0.94 3.3599 -1.1158 40.3389
NCI-H1694 GDSC1; CTRP2; CTRP1 -0.7993 6.2595 -1.6623 41.7709
LK-2 GDSC1 -0.791 5.5962 -2.7406 36.4759
NCI-H1703 GDSC1; CTRP2 -0.7331 5.4088 -1.3639 40.0376
NCI-H187 GDSC1 -0.693 4.1079 -1.9565 32.9009
NCI-H810 GDSC1; CTRP2; CTRP1 -0.5905 8.1945 -2.1764 40.9623
NCI-H1876 GDSC1; CTRP1 -0.4579 4.0833 -1.7085 24.2608
NCI-H2085 GDSC1 -0.4232 3.7225 -1.5099 29.1415
NCI-H1975 GDSC1; CTRP2; CTRP1 -0.4155 9.661 -2.5886 40.9319
COR-L95 GDSC1; CTRP2 -0.4141 8.7348 -2.2097 40.3207
NCI-H2009 GDSC1; CTRP2; CTRP1 -0.399 4.4465 -0.7421 39.8673
NCI-H526 GDSC1; CTRP2 -0.3199 8.7431 -2.1136 39.8266
NCI-H322 CTRP2 -0.2676 5.7006 -0.9444 37.2816
EMC-BAC-1 GDSC1 -0.2571 8.3932 -3.5831 36.3516
NCI-H510A GDSC1 -0.2026 6.4936 -2.6044 33.0348
NCI-H1734 GDSC1; CTRP2 -0.0781 5.9784 -0.8264 36.2867
HCC33 GDSC1; CTRP1 -0.0678 9.0564 -1.9723 46.2454
NCI-H2869 GDSC1 -0.0529 5.4578 -1.9614 29.5714
NCI-H838 GDSC1; CTRP2 -0.0373 12.3636 -3.3948 40.7046
ABC-1 GDSC1 0.0053 5.9437 -2.142 30.1351
UMC-11 GDSC1 0.0739 6.7815 -2.4873 31.2914
SBC-1 GDSC1 0.1019 4.2565 -1.2371 24.8411
NCI-H2106 CTRP2 0.1259 14.6156 -4.2736 41.2142
NCI-H460 GDSC1; CTRP2; CTRP1 0.1385 4.0851 -0.0815 33.3961
NCI-H1105 CTRP2; CTRP1 0.1709 7.9765 -1.2867 36.4916
SK-MES-1 GDSC1; CTRP2 0.2096 11.8054 -2.8929 39.2683
COR-L47 CTRP2 0.2349 10.9853 -2.4986 38.5831
MOR/CPR CTRP2 0.312 5.0818 -0.1305 32.9504
NCI-H1648 GDSC1 0.3261 7.8587 -2.789 31.3507
Lu-165 GDSC1 0.3299 7.069 -2.3949 29.7663
NCI-H82 GDSC1; CTRP1 0.4028 7.5928 -0.8847 42.7535
NCI-H1650 GDSC1; CTRP2 0.4214 6.1756 -0.3495 33.2278
A-549 GDSC1; CTRP2; CTRP1 0.4292 4.3423 0.1824 31.629
NCI-H841 GDSC1; CTRP2; CTRP1 0.4644 6.013 -0.2484 32.7858
NCI-H522 GDSC1; CTRP2; CTRP1 0.4938 10.2759 -1.9137 36.7653
NCI-H1688 GDSC1 0.5924 6.8212 -2.0363 26.9983
NCI-H1304 GDSC1 0.812 4.8332 -0.8544 19.1238
NCI-H2591 GDSC1 1.0045 7.8026 -2.1646 25.9332
NCI-H358 GDSC1; CTRP2; CTRP1 1.0849 14.9693 -3.5014 37.6766
DMS 53 GDSC1; CTRP2 1.1102 8.0057 -0.2483 31.632
NCI-H661 GDSC1; CTRP2; CTRP1 1.1244 11.765 -1.9521 34.9154
NCI-H2373 GDSC1 1.1446 8.6504 -2.4687 26.7816
NCI-H520 GDSC1; CTRP2 1.1549 19.219 -5.4979 39.8439
SK-LU-1 GDSC1; CTRP2; CTRP1 1.1553 8.5209 -0.4761 31.204
Calu-3 GDSC1; CTRP2; CTRP1 1.1666 35.2794 -13.4062 44.3062
NCI-H727 GDSC1; CTRP2; CTRP1 1.2234 12.1568 -2.0363 34.7981
NCI-H2196 GDSC1; CTRP2 1.2694 8.7587 -0.4597 30.8065
CPC-N GDSC1 1.2961 10.545 -3.2884 29.4191
CAL-12T GDSC1; CTRP2; CTRP1 1.346 8.8038 -0.4 30.4022
VMRC-LCD CTRP2; CTRP1 1.4563 11.8305 -1.6543 33.3253
NCI-H196 GDSC1; CTRP2 1.4727 10.8299 -1.1806 32.1176
HCC827 GDSC1; CTRP2; CTRP1 1.4832 10.3171 -1.3959 28.9583
NCI-H2122 GDSC1; CTRP2; CTRP1 1.4879 8.7578 -0.2339 29.4864
NCI-H1838 GDSC1; CTRP2 1.4937 19.743 -5.4395 39.016
Lu-139 GDSC1 1.5148 11.1693 -3.4189 29.1177
Sq-1 CTRP2; CTRP1 1.5511 7.8743 0.2092 27.9119
A-427 GDSC1 1.5608 9.8386 -2.7157 26.326
NCI-H1792 GDSC1; CTRP2; CTRP1 1.5617 8.4106 -0.0017 28.6171
NCI-H2087 GDSC1; CTRP2 1.6833 14.1393 -2.5375 34.4579
NCI-H1836 GDSC1; CTRP1 1.6839 7.7066 -1.5502 16.3578
NCI-H209 GDSC1 1.7362 8.2596 -1.7841 21.2807
T3M-10 CTRP2; CTRP1 1.7363 8.2037 0.2622 27.1932
RERF-LC-KJ GDSC1; CTRP1 1.7542 7.7829 0.465 29.1035
NCI-H1436 GDSC1 1.7625 8.5987 -1.9323 21.975
NCI-H322M GDSC1 1.8349 12.7091 -3.9265 29.7063
PaCa-3 GDSC1 1.8814 13.1843 -4.1261 30.1508
IST-SL1 GDSC1 2.029 8.2682 -1.5564 19.0105
NCI-H2228 GDSC1; CTRP2 2.0345 11.0676 -0.7358 29.3661
NCI-H1666 GDSC1; CTRP2; CTRP1 2.0371 32.3529 -11.1815 42.1232
LC-1/sq-SF CTRP2; CTRP1 2.1197 8.9335 0.34 25.9085
NCI-H1581 GDSC1; CTRP2 2.148 9.2679 0.2108 26.1922
NCI-H345 GDSC1 2.1641 3.1411 1.0132 0.8368
NCI-H2141 GDSC1; CTRP2; CTRP1 2.1886 9.2257 0.2708 25.8822
NCI-H1573 GDSC1; CTRP2; CTRP1 2.2049 16.4162 -3.144 34.2722
NCI-H1373 CTRP2; CTRP1 2.2258 13.5299 -1.7198 31.3837
ChaGo-K-1 GDSC1; CTRP2; CTRP1 2.2749 11.7064 -0.7971 28.9401
NCI-H1963 GDSC1; CTRP1 2.2771 8.8014 -1.6296 15.2065
RERF-LC-Sq1 GDSC1 2.3303 8.1838 -1.2838 16.4202
NCI-H2731 GDSC1 2.3461 8.857 -1.6046 18.2604
HCC95 CTRP2 2.3513 12.359 -1.0437 29.3456
NCI-H1092 GDSC1; CTRP2 2.4167 9.6344 0.3104 25.1292
NCI-H1435 GDSC1; CTRP2; CTRP1 2.4223 10.5707 -0.1154 26.5516
NCI-H2405 GDSC1; CTRP2; CTRP1 2.4367 15.3036 -2.3847 32.284
COR-L88 GDSC1; CTRP2; CTRP1 2.6423 10.0516 0.3443 24.4823
DMS 273 GDSC1; CTRP2; CTRP1 2.848 14.2071 -1.4671 29.2175
NCI-H1437 GDSC1; CTRP1 3.0062 16.4748 -2.4386 35.946
NCI-H2170 GDSC1; CTRP2 3.0367 11.026 0.251 23.7218
NCI-H2818 GDSC1 3.0577 7.2476 -0.321 8.0382
NCI-H2081 GDSC1; CTRP2; CTRP1 3.089 7.4528 1.9808 17.2085
NCI-H1568 GDSC1; CTRP2; CTRP1 3.0895 8.7193 1.4084 19.4996
NCI-H3255 GDSC1; CTRP1 3.1378 11.9445 -2.5366 17.4137
NCI-H1993 GDSC1 3.1379 9.9465 -1.56 15.6773
NCI-H2803 GDSC1 3.193 9.22 -1.1702 13.2357
Calu-1 CTRP2 3.1985 12.6977 -0.319 26.0056
DMS 79 GDSC1; CTRP2 3.2373 13.3948 -0.7183 26.2302
LC-1/sq GDSC1 3.2697 8.3967 -0.7256 10.23
NCI-H2804 GDSC1 3.2784 7.7155 -0.4 8.0553
NCI-H1693 GDSC1; CTRP2 3.3048 9.7045 1.1429 19.8948
NCI-H524 GDSC1; CTRP2 3.3304 8.5944 1.6963 17.7112
HCC366 CTRP2 3.3741 12.0856 0.0505 23.5566
NCI-H69 GDSC1 3.3891 5.592 0.5973 1.5491
NCI-H1930 CTRP1 3.4721 11.9874 0.1972 24.9086
NCI-H1781 GDSC1; CTRP1 3.5346 5.2969 0.7741 0.4987
NCI-H513 GDSC1 3.5499 8.6831 -0.6804 9.2685
NCI-H2722 GDSC1 3.5641 9.6822 -1.1419 12.1139
NCI-H2347 GDSC1 3.5886 5.7552 0.6227 1.2185
NCI-H720 GDSC1 3.6218 11.7515 -2.0959 17.2336
NCI-H2461 GDSC1 3.6254 9.2314 -0.8891 10.4137
NCI-H2595 GDSC1 3.6872 11.9712 -2.1566 17.3657
NCI-H748 GDSC1 3.7531 8.2098 -0.3392 6.6331
HCC78 GDSC1; CTRP2; CTRP1 3.7644 10.147 1.3692 18.0145
NCI-H2023 GDSC1; CTRP2; CTRP1 3.817 11.4906 0.7488 20.1282
NCI-H1355 GDSC1; CTRP2; CTRP1 3.9965 14.3278 -0.4882 23.8603
SCLC-21H CTRP2; CTRP1 4.1597 5.9025 2.4107 1.3488
HCC1833 CTRP2; CTRP1 4.3192 15.6219 -0.8602 24.1865
NCI-H889 CTRP2 4.4676 16.2099 -1.026 24.3376
NCI-H1651 GDSC1; CTRP2 4.5603 12.6283 0.9461 18.6983
LCLC-103H GDSC1; CTRP2; CTRP1 4.6125 11.6031 1.4077 15.9998
NCI-H2029 GDSC1; CTRP2; CTRP1 4.6593 16.9434 -1.2196 24.5206
NCI-H1563 GDSC1; CTRP2 4.7825 9.259 2.8187 10.8745
EKVX GDSC1; CTRP2 4.7855 15.0608 -0.0738 21.6602
NCI-H2444 GDSC1; CTRP2 4.9825 10.2241 2.4027 11.1938
NCI-H226 GDSC1; CTRP2 5.2948 10.8987 2.3232 10.9213
RERF-LC-Ad2 CTRP2 5.3642 23.7233 -4.0299 29.2839
HCC15 GDSC1; CTRP2; CTRP1 5.4335 16.689 -0.4569 20.7357
BEN GDSC1; CTRP2; CTRP1 5.5477 13.4059 1.2854 14.6195
NCI-H2126 CTRP2; CTRP1 5.5993 17.7451 -0.8396 21.6084
NCI-H1793 GDSC1; CTRP2; CTRP1 6.2388 8.7342 4.2133 2.5626
LOU-NH91 GDSC1; CTRP2 6.2949 17.0708 0.0389 17.5815
RERF-LC-Ad1 CTRP2 6.7206 7.5875 4.7681 0.0373
SW1573 GDSC1; CTRP2 6.729 17.2394 0.2876 16.012
IA-LM GDSC1; CTRP2 6.7401 9.061 4.2112 1.2878
DMS 454 CTRP2 6.7475 16.1291 0.9724 14.4459
LUDLU-1 CTRP2 6.8884 11.1626 3.3515 4.2425
NCI-H2172 GDSC1; CTRP2; CTRP1 7.3058 13.3052 2.6124 6.5604
NCI-H1869 GDSC1; CTRP2 7.3815 19.9079 -0.5409 17.5638
NCI-H2291 GDSC1; CTRP2 7.4587 9.3525 4.4212 0.3386
HCC2279 CTRP2 7.4902 18.1973 0.3781 14.4766
NCI-H2342 GDSC1; CTRP2; CTRP1 7.6368 9.3365 4.4948 0.1775
NCI-H1623 GDSC1; CTRP2 7.7074 9.7737 4.3653 0.3586
NCI-H1395 CTRP2 7.8979 10.1614 4.2986 0.4171
COLO 699 CTRP2; CTRP1 8.0885 15.7851 1.9496 8.0384
HCC4006 CTRP2; CTRP1 8.2194 20.2784 -0.1162 14.9698
SBC-5 GDSC1; CTRP2 8.4305 19.8263 0.2496 13.4987
NCI-H441 GDSC1; CTRP2; CTRP1 8.7317 16.0217 2.2392 6.2099
LK2 CTRP2 9.9618 22.2277 0.1237 11.862
HCC1171 CTRP2 14.0904 33.4444 -2.5119 14.2577
Hs 888.Lu CTRP2 0.6736 8.6655 -1.0391 34.2227
⏷ Show the Full List of 217 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 -0.998 8.6668 -4.408 41.3238
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 -11.5435 -10.0282 -11.5435 99.6337
Yamato-SS CTRP2 -0.9421 3.8023 -1.1787 41.4833
TE 441.T GDSC1; CTRP2 -4.3688 -2.1586 -4.369 62.6872
TE 617.T CTRP2 -4.2909 -2.1614 -4.291 62.1748
Hs 633.T GDSC1 -4.0271 -2.2864 -4.0289 66.9442
EW-8 GDSC1 -3.9263 -1.4733 -3.9458 64.9799
Rh18 CTRP2 -3.7469 0.817 -3.8064 58.0922
RD GDSC1; CTRP2 -3.1609 0.6109 -3.1895 54.5455
G-402 GDSC1; CTRP2 -3.0404 -0.0909 -3.0468 53.8322
SW982 GDSC1; CTRP2 -2.8325 -1.4218 -2.8325 53.4781
MFH-ino GDSC1 -2.6992 0.2977 -2.832 50.622
G-401 GDSC1; CTRP2; CTRP1 -2.4852 0.5612 -2.4972 50.2096
TTC-709 CTRP2 -2.4847 2.4234 -2.623 51.088
A-204 GDSC1; CTRP2 -2.4349 3.791 -2.793 50.7249
SK-LMS-1 GDSC1; CTRP2 -2.3479 0.2713 -2.3527 49.2511
Tm87-16 CTRP2 -0.7691 5.3085 -1.3425 41.0794
Rh41 GDSC1; CTRP2 -0.7553 5.2477 -1.3416 40.0814
BT-16 CTRP2 -0.7444 6.503 -1.6824 41.5785
SW872 GDSC1 -0.5628 3.6264 -1.6089 30.449
BT-12 CTRP2 -0.0514 7.4127 -1.2547 38.1017
RKN GDSC1; CTRP2; CTRP1 0.013 6.3949 -0.8667 36.0578
HT-1080 GDSC1; CTRP2; CTRP1 0.8349 5.9216 0.1841 30.2192
KYM-1 GDSC1; CTRP2 1.0779 6.1203 0.4226 29.6773
GCT GDSC1; CTRP2 1.3158 3.5786 1.2699 26.0465
SK-UT-1 GDSC1; CTRP2 1.6479 8.9942 -0.1734 28.831
VA-ES-BJ GDSC1 2.1859 8.6537 -1.6263 18.8946
Rh30 GDSC1 2.2797 13.7207 -4.0743 28.8155
SW684 GDSC1 3.3579 5.1726 0.7479 0.8761
MES-SA GDSC1; CTRP2 6.0231 7.3863 4.5534 0.7757
Hs 729.T CTRP2 8.1917 37.294 -8.5384 31.3371
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 -3.5236 -2.3517 -3.5236 57.0814
SYO-1 CTRP2 -2.1252 0.888 -2.1382 48.785
P-STS CTRP2 1.1201 8.9546 -0.6985 31.9288
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -2.7858 -1.4373 -2.7859 53.1682
A2780 GDSC1; CTRP2; CTRP1 -4.5563 -2.49 -4.5564 63.9419
OVCAR-8 GDSC1; CTRP2; CTRP1 -4.4105 -3.4498 -4.4105 62.9897
IGROV-1 GDSC1; CTRP2; CTRP1 -3.3024 1.0478 -3.36 55.3531
ES-2 GDSC1 -3.125 -0.4339 -3.1866 55.5621
Caov-3 GDSC1; CTRP2; CTRP1 -2.9119 -0.5202 -2.9133 52.9995
OV7 CTRP2; CTRP1 -2.6877 0.1563 -2.6943 51.5034
COV434 CTRP2; CTRP1 -2.4491 3.8029 -2.8108 50.8053
MCAS CTRP2 -2.2049 3.6428 -2.5331 48.4876
JHOC-5 CTRP2; CTRP1 -2.1879 1.1343 -2.213 48.2081
RMUG-S CTRP1 -1.5037 0.7351 -2.9362 7.275
OV-90 GDSC1; CTRP2; CTRP1 -0.9808 3.845 -1.2468 40.8108
TOV-112D GDSC1; CTRP2 -0.8332 6.921 -1.9653 41.5253
HEY A8 CTRP2; CTRP1 -0.3926 6.1356 -1.2159 38.4392
JHOS-2 GDSC1; CTRP2 -0.1448 9.4091 -2.2057 39.3633
OC 314 GDSC1; CTRP2 0.179 6.3282 -0.6222 35.7924
JHOS-4 CTRP1 0.2657 7.0919 -0.8402 38.3427
SNU-8 CTRP2 0.5513 7.2979 -0.6169 33.5378
SNU-119 CTRP2 0.8151 15.6917 -4.1138 39.1654
OVISE GDSC1; CTRP2 0.9595 5.7658 0.3704 29.2096
DOV13 GDSC1; CTRP2 1.5661 5.2812 1.1813 24.5152
ONCO-DG-1 CTRP2 1.6713 9.739 -0.483 29.679
OVK18 GDSC1; CTRP2; CTRP1 2.089 5.9977 1.5163 21.7365
OV56 GDSC1; CTRP2 2.1969 7.2141 1.1601 22.7392
FU-OV-1 GDSC1; CTRP2 2.3856 10.0202 0.1001 25.9041
JHOM-1 CTRP2; CTRP1 2.5418 8.8051 0.8172 23.0389
SK-OV-3 GDSC1; CTRP2; CTRP1 2.8771 13.847 -1.2637 28.6355
OVCAR-5 GDSC1; CTRP2 3.2461 14.2679 -1.0446 27.9093
OVCAR-3 GDSC1 3.3427 5.3711 0.6641 1.2688
SNU-840 CTRP2; CTRP1 3.4461 13.2023 -0.4327 24.8961
Caov-4 GDSC1 3.6579 5.7274 0.6633 0.9801
TOV-21G GDSC1; CTRP2 3.6958 10.7543 1.0002 19.4924
OVTOKO GDSC1; CTRP2 3.8949 12.2323 0.4526 20.9937
TYK-nu GDSC1; CTRP2; CTRP1 4.0026 9.3641 1.9649 15.0528
EFO-27 GDSC1; CTRP2; CTRP1 4.4258 14.3116 -0.1143 21.7089
OVKATE GDSC1; CTRP1 4.6044 12.4969 -1.7958 11.0611
OAW42 GDSC1; CTRP2; CTRP1 4.8154 11.6238 1.562 14.9113
OVMANA CTRP1 4.9296 18.5153 -1.7773 27.1035
OVCAR-4 GDSC1; CTRP2; CTRP1 5.0043 11.8761 1.595 14.4034
ES2 CTRP2 5.4704 14.3392 0.747 16.677
EFO-21 GDSC1; CTRP2; CTRP1 5.4778 15.9305 -0.0319 19.3749
OAW28 GDSC1; CTRP2 5.4846 10.6078 2.6204 9.3498
RMG-I GDSC1; CTRP2; CTRP1 6.9737 18.3976 -0.1005 16.8683
COV644 CTRP2; CTRP1 7.5921 14.604 2.1846 7.8144
COV362 CTRP2; CTRP1 7.7262 14.9051 2.1299 7.8416
COV318 CTRP1 8.9863 20.4174 0.3546 13.4374
OVSAHO CTRP2 9.1233 15.6084 2.6495 4.3741
Kuramochi GDSC1; CTRP2 9.6982 20.8887 0.5834 10.7346
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 2.84 13.7823 -1.2747 28.7028
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; CTRP2; CTRP1 -3.1541 2.0985 -3.3033 54.2722
NCI-H2452 GDSC1; CTRP2 0.4423 3.8232 0.2949 31.1506
NCI-H28 GDSC1; CTRP2; CTRP1 1.3132 7.2779 0.2066 28.704
MPP 89 GDSC1; CTRP2 2.1328 6.2861 1.4585 21.8222
NCI-H2052 GDSC1; CTRP2; CTRP1 2.2937 10.2959 -0.1123 26.8876
IST-Mes1 GDSC1; CTRP2 3.6167 9.5899 1.4945 17.8046
ACC-MESO-1 CTRP2 4.3788 23.3326 -4.6601 32.1174
JL-1 CTRP2 13.0222 42.451 -7.4996 24.4271
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
22Rv1 GDSC1; CTRP2 -2.5849 3.8367 -2.9857 50.7096
PC-3 GDSC1 -1.7824 4.2854 -3.1517 43.3623
LNCaP clone FGC GDSC1; CTRP2 0.0921 9.8527 -2.1485 38.4617
VCaP GDSC1; CTRP2 2.2003 15.9815 -2.9438 33.89
DU145 GDSC1; CTRP2 2.9564 15.0997 -1.8142 29.7373
NCI-H660 CTRP2 4.2627 14.3412 -0.1676 23.0715
PaCa-3 CTRP2; CTRP1 4.6547 9.8466 2.3204 12.2714
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 -3.3237 0.1572 -3.3397 55.6447
A-253 GDSC1 1.9118 7.7752 -1.4029 18.5045
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 -5.2382 -3.5914 -5.2384 81.0945
Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RF-48 GDSC1 -4.4508 -0.1457 -4.6433 66.8993
NCI-N87 GDSC1; CTRP2 -4.2449 4.3244 -4.9061 58.7899
GSU CTRP2 -4.1899 -3.8963 -4.1899 61.5202
SNU-1 GDSC1; CTRP2 -4.1437 3.221 -4.5504 58.9871
AGS GDSC1; CTRP2; CTRP1 -3.5364 -1.4719 -3.5366 57.1608
HGC-27 GDSC1; CTRP2 -2.7652 0.6661 -2.784 52.9816
NCC-StC-K140 CTRP2 -2.6891 5.7739 -3.6054 51.1421
TGBC11TKB GDSC1 -2.6059 0.8302 -2.8363 49.5939
IM95 GDSC1; CTRP2 -2.3985 5.0939 -3.0918 49.6684
SNU-620 CTRP2 -2.376 6.0636 -3.3534 49.5758
GSS CTRP2 -1.7416 4.355 -2.1851 45.8153
ECC12 CTRP2 -0.4751 6.7138 -1.5054 39.3063
Hs 746.T GDSC1; CTRP2 -0.2277 14.1737 -4.4165 42.3598
Fu97 GDSC1; CTRP2; CTRP1 -0.1351 7.5162 -1.4291 37.9361
SNU-668 CTRP2 0.5643 8.1428 -0.9377 34.3305
NUGC-3 GDSC1; CTRP2 0.6135 13.4841 -3.2643 38.5999
SNU-16 GDSC1; CTRP2 0.7108 3.868 0.5764 29.3236
SNU-601 CTRP2 1.002 7.4827 -0.1549 31.7085
MKN28 GDSC1 1.388 11.1144 -3.4965 29.8032
SNU-216 CTRP2 1.416 11.7794 -1.5985 34.0586
GCIY GDSC1 1.4582 6.4214 -1.092 18.1698
SNU-5 GDSC1; CTRP2 1.6973 5.1116 1.3731 23.4292
KE-39 CTRP2 1.8395 14.1431 -2.3034 34.0967
RERF-GC-1B GDSC1 1.8923 10.5661 -2.81 25.5924
TMK-1 GDSC1 2.0963 8.9116 -1.8239 20.2748
HuG1-N CTRP2 2.316 13.187 -1.4763 30.5283
LMSU CTRP2 2.6816 10.9446 -0.049 25.6004
ECC10 GDSC1; CTRP2 2.7387 12.3358 -0.6647 27.307
NUGC-4 GDSC1; CTRP2; CTRP1 2.7529 29.0342 -8.9008 39.6109
OCUM-1 GDSC1 3.025 6.826 -0.1446 6.9009
HSC-39 GDSC1 3.0465 4.5807 0.8418 0.7427
SCH GDSC1 3.4421 4.7504 0.9345 0.2207
KATO III CTRP2 4.5737 27.9205 -6.7882 34.6005
MKN7 GDSC1; CTRP2; CTRP1 4.5969 12.904 0.745 18.4973
MKN1 GDSC1; CTRP2 6.2958 12.5892 2.2573 9.4445
MKN45 GDSC1; CTRP2 6.725 7.6199 4.7588 0.0435
23132/87 GDSC1; CTRP2 7.8925 16.8175 1.3289 10.5691
MKN74 CTRP2; CTRP1 7.9388 20.9584 -0.6373 17.0299
SH-10-TC CTRP2; CTRP1 10.9136 28.5882 -2.2568 17.2444
SNG-M GDSC1; CTRP2; CTRP1 -0.948 4.6123 -1.3803 41.0095
SNU-685 CTRP2 1.3781 5.6336 0.8681 26.1989
SNU-1077 CTRP2 7.9449 14.2625 2.5699 5.9178
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 -3.3282 -0.4238 -3.3328 55.7369
K5 GDSC1 -3.1129 -1.9776 -3.1131 55.8575
8505C GDSC1; CTRP2 -2.1014 3.0576 -2.3152 47.7952
TT2609-C02 GDSC1; CTRP2 -1.4421 5.3891 -2.1316 44.3439
BHT-101 GDSC1; CTRP2 -0.8749 3.987 -1.1606 40.1773
CGTH-W-1 GDSC1; CTRP2 0.003 3.9391 -0.1998 34.2356
HTC-C3 GDSC1 0.5278 4.4957 -0.948 20.9904
FTC-238 CTRP2 0.6476 33.3688 -12.9304 44.907
B-CPAP GDSC1; CTRP2 0.9274 8.6154 -0.7534 32.6789
ML-1 [Human leukemia] GDSC1; CTRP2 1.4202 8.7387 -0.2954 29.8721
ASH-3 GDSC1 1.4542 6.1629 -0.966 17.3569
TT GDSC1; CTRP2 1.4882 5.2919 1.0931 25.0677
KMH-2 GDSC1 1.9894 8.2141 -1.5604 19.1661
8305C GDSC1; CTRP2 2.6675 7.8978 1.3533 20.7313
IHH-4 GDSC1 3.3868 4.8301 0.8861 0.3648
WRO GDSC1 3.5039 10.8563 -1.7451 15.719
CAL-62 GDSC1; CTRP2 6.7484 8.1776 4.5702 0.3047
FTC-133 GDSC1; CTRP2 7.4757 15.4708 1.692 9.8324
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-04B GDSC1 -4.4237 1.7976 -5.0775 63.2597
PCI-06A GDSC1 -4.1726 -1.2834 -4.2113 67.0174
BB30-HNC GDSC1 -4.1394 -1.923 -4.1481 67.7373
BICR 16 CTRP2 -3.8248 8.02 -5.5388 56.0483
PE/CA-PJ34 (clone C12) CTRP2 -3.6711 -1.4828 -3.6714 58.0528
BICR 6 CTRP2 -3.6563 3.1541 -4.0097 56.6412
JHU-011 GDSC1 -3.648 -0.431 -3.741 60.918
NCI-H3118 GDSC1 -3.3485 3.744 -4.5825 54.8384
SAS GDSC1 -3.3339 4.0986 -4.7052 54.5667
PE/CA-PJ49 CTRP2 -3.3206 -1.659 -3.3206 55.7281
YD-10B CTRP2 -3.2652 4.0371 -3.7702 54.3377
SNU-1066 CTRP2 -3.2341 -0.2197 -3.2406 55.1069
SCC-9 GDSC1; CTRP2; CTRP1 -3.178 -0.495 -3.1809 54.7569
HSC-3 GDSC1; CTRP2 -3.1617 -0.8488 -3.1626 54.6623
CAL-27 GDSC1; CTRP2 -3.1139 -0.567 -3.1159 54.3375
BICR 31 GDSC1; CTRP2 -3.0871 0.5309 -3.1106 54.0847
SCC-4 GDSC1; CTRP2 -3.0718 -0.6004 -3.0732 55.0561
BICR 56 CTRP2 -3.0381 3.1493 -3.3241 54.2121
OSC-20 GDSC1 -2.9745 1.5203 -3.4159 53.1053
CAL-33 GDSC1; CTRP2 -2.9469 1.233 -2.9985 54.0769
SCC-25 GDSC1; CTRP2 -2.9319 1.3462 -2.9956 53.0081
BB49-HNC GDSC1 -2.9188 -0.1719 -2.9981 53.1658
BHY GDSC1; CTRP2 -2.8517 5.3235 -3.6507 51.9926
HSC-2 GDSC1; CTRP2; CTRP1 -2.5533 -0.829 -2.5534 50.6646
SNU-899 CTRP2 -2.4398 -0.3637 -2.4405 49.8609
BICR 18 CTRP2 -2.2618 0.2437 -2.2655 48.6784
Ca9-22 GDSC1 -2.0843 3.512 -3.1475 45.4244
PCI-38 GDSC1 -2.0451 0.9816 -2.2606 43.3147
YD-8 CTRP2 -1.8365 1.5435 -1.8712 45.9058
HO-1-u-1 GDSC1 -1.2752 3.214 -2.1729 37.3322
BICR 22 GDSC1; CTRP2 -1.1785 2.8297 -1.2951 41.7547
SNU-1076 CTRP2 -1.1099 4.9277 -1.6404 42.1378
SKN-3 GDSC1 -1.0644 4.4141 -2.4705 37.108
SNU-1214 CTRP2 -0.5078 8.2937 -2.1323 40.5405
DOK GDSC1 -0.4831 4.6694 -2.0041 31.966
SCC-15 GDSC1 -0.4658 5.8561 -2.5477 34.1168
BICR 10 GDSC1 -0.1211 4.2442 -1.4487 27.2098
HO-1-N-1 GDSC1 -0.0917 5.4849 -2.0114 29.9991
SNU-1041 CTRP2 -0.0069 5.8189 -0.6976 35.6946
OSC-19 GDSC1 0.0385 7.5023 -2.874 32.9029
SAT [Human HNSCC] GDSC1 0.0951 7.3031 -2.7242 32.1122
PE/CA-PJ15 GDSC1; CTRP2 0.1405 5.9717 -0.5866 34.8698
JHU-022 GDSC1 0.2212 8.1496 -3.0273 32.641
LB771-HNC GDSC1 0.9349 7.1853 -1.9165 24.983
HSC-4 GDSC1; CTRP2 1.0428 9.7552 -1.1284 33.2736
FaDu GDSC1; CTRP2 1.8744 13.4609 -2.0289 32.9383
BICR 78 GDSC1 2.352 10.3612 -2.3458 22.0756
PCI-15A GDSC1 2.417 4.2532 0.667 2.5865
KOSC-2 GDSC1 2.8655 7.2491 -0.4473 9.3842
Detroit 562 GDSC1; CTRP2 3.172 10.8679 0.4555 22.6933
KON GDSC1 3.3694 8.6258 -0.769 10.2659
PCI-30 GDSC1 3.423 8.4967 -0.6736 9.5214
SNU-46 CTRP2 4.6754 16.5632 -1.0253 23.9037
PE/CA-PJ41 (clone D2) CTRP2 4.9274 14.2244 0.3565 19.1094
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCaBER CTRP2 -4.7095 -1.6508 -4.712 64.7802
UM-UC-3 GDSC1; CTRP2; CTRP1 -4.3078 -3.0546 -4.3078 62.3421
JMSU-1 CTRP2 -4.2374 -3.0107 -4.2374 61.8367
253J CTRP2 -4.1605 -0.9485 -4.1658 61.1601
RT-112 GDSC1; CTRP2 -3.8121 1.2103 -3.9051 58.318
RT-4 GDSC1; CTRP2; CTRP1 -3.5579 1.7387 -3.6894 56.7077
TCCSUP GDSC1; CTRP2 -2.6387 0.8208 -2.6625 51.1662
647V GDSC1; CTRP2 -2.4914 0.2992 -2.4981 50.2035
U-BLC1 CTRP2 -2.2709 4.0049 -2.6595 49.7783
5637 GDSC1; CTRP2; CTRP1 -2.0925 2.3021 -2.2015 47.708
BFTC-905 GDSC1 -1.9339 1.3469 -2.2319 42.3012
639V GDSC1; CTRP2 -1.7459 1.1697 -1.7617 45.2724
VM-CUB-1 CTRP2 -0.7662 5.1695 -1.3315 40.1046
KU-19-19 GDSC1; CTRP2 -0.6671 1.9527 -0.6867 38.113
253J-BV CTRP2 -0.538 312.1703 -153.195 49.6623
SW1710 GDSC1; CTRP2 -0.4797 6.0585 -1.2888 38.8786
KMBC-2 CTRP2; CTRP1 -0.435 7.8217 -1.8191 40.5867
UM-UC-1 CTRP2 0.5886 7.1686 -0.5276 33.1681
BC-3C CTRP2 1.5209 8.153 0.0603 28.4797
HT-1376 GDSC1; CTRP2; CTRP1 1.8866 8.6047 0.2487 26.8687
CAL-29 GDSC1; CTRP2 2.2902 12.4785 -1.1594 29.8066
HT-1197 GDSC1; CTRP2 2.363 6.7384 1.5289 20.904
T24 GDSC1; CTRP2 3.2783 13.2776 -0.623 25.8575
SW780 GDSC1 3.4868 8.3942 -0.5853 8.7992
J82 GDSC1; CTRP2 6.7362 15.5354 1.1334 13.0396
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KGN GDSC1 -5.2168 -2.4267 -5.2311 77.784
DSH1 GDSC1 -5.0227 -2.7359 -5.0272 77.2772
PA-1 GDSC1 -4.8719 -3.6987 -4.8719 77.6128
SW954 GDSC1 -4.7917 -3.0793 -4.7923 75.9866
NEC8 GDSC1 -4.3266 -2.9263 -4.3268 70.8283
BPH-1 GDSC1 -3.899 -1.5151 -3.916 64.7561
C-33 A GDSC1 -3.6778 -0.6866 -3.7437 61.5163
OMC-1 [Human cervical carcinoma] GDSC1 -3.3269 0.2718 -3.5046 57.1414
OVCA420 GDSC1 -3.2786 0.0681 -3.4173 56.8381
HEY GDSC1 -3.2283 5.2363 -5.0592 53.48
Ca Ski GDSC1 -2.9976 2.5812 -3.7784 52.9029
LB831-BLC GDSC1 -2.9184 -0.6394 -2.9516 53.2886
OVMIU GDSC1 -2.742 3.1267 -3.6995 50.778
ME-180 GDSC1 -2.7238 1.2508 -3.0681 50.8022
SKN GDSC1 -2.2898 4.0358 -3.5768 47.3425
ACC-OV7 GDSC1 -2.0979 0.149 -2.1655 43.4559
DoTc2 4510 GDSC1 -1.4407 3.6382 -2.5219 39.6085
SW962 GDSC1 -0.9223 3.7541 -2.0336 34.5724
OV17R GDSC1 -0.894 4.2797 -2.2373 35.249
C-4-I GDSC1 -0.7499 3.1563 -1.5984 31.4624
JAR GDSC1 0.6339 5.9164 -1.5507 24.2605
CAL-39 GDSC1 0.6355 6.9903 -2.0819 27.0366
HT-3 GDSC1 0.7105 7.7278 -2.3826 28.1063
MS751 GDSC1 0.7411 7.5425 -2.2634 27.4484
NT2-D1 GDSC1 0.8917 10.0071 -3.3622 31.1159
HeLa GDSC1; CTRP2 1.4248 9.0319 -0.4185 30.2189
SiSo GDSC1 1.5635 7.8269 -1.7081 21.4782
JHOS-3 GDSC1 2.0676 6.8455 -0.8205 14.2661
HEC-1 GDSC1 2.7488 4.8119 0.6044 2.4
OVCA433 GDSC1 2.8413 8.6633 -1.1459 14.0486
SiHa GDSC1 2.9223 4.1944 0.9358 0.4683
JEG-3 GDSC1 2.9868 4.9242 0.6782 1.6104
SKG-IIIa GDSC1 3.0274 5.0864 0.631 1.8192
SW756 GDSC1 3.0497 9.1446 -1.233 14.0034
NCC-IT GDSC1 3.3115 9.0528 -1.0099 11.938
PEO1 GDSC1 3.5506 12.335 -2.4294 19.0258
UWB1.289 GDSC1 4.5688 6.863 0.6086 0.588
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

References

1 Heat shock protein 90: inhibitors in clinical trials. J Med Chem. 2010 Jan 14;53(1):3-17.
2 The Hsp90 inhibitor SNX-2112, induces apoptosis in multidrug resistant K562/ADR cells through suppression of Akt/NF-B and disruption of mitochondria-dependent pathways. Chem Biol Interact. 2013 Sep 5;205(1):1-10. doi: 10.1016/j.cbi.2013.06.007. Epub 2013 Jun 15.