Details of the Drug

General Information of Drug (ID: DMB8MNU)

Drug Name
CHIR-99021
Synonyms CHIR99021; CHIR 99021; CT-99021; CT99021
Indication
Disease Entry ICD 11 Status REF
Allergic inflammation 4A80-4A85 Patented [1]
Graft rejection NE84 Patented [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 465.3
Logarithm of the Partition Coefficient (xlogp) 4.3
Rotatable Bond Count (rotbonds) 7
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C22H18Cl2N8
IUPAC Name
6-[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethylamino]pyridine-3-carbonitrile
Canonical SMILES
CC1=CN=C(N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N
InChI
InChI=1S/C22H18Cl2N8/c1-13-10-29-21(31-13)17-12-30-22(32-20(17)16-4-3-15(23)8-18(16)24)27-7-6-26-19-5-2-14(9-25)11-28-19/h2-5,8,10-12H,6-7H2,1H3,(H,26,28)(H,29,31)(H,27,30,32)
InChIKey
AQGNHMOJWBZFQQ-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
9956119
ChEBI ID
CHEBI:91091
CAS Number
252917-06-9
TTD ID
D0YK9D
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cyclin-dependent kinase 1 (CDK1) TTH6V3D CDK1_HUMAN Inhibitor [2]
Extracellular signal-regulated kinase 2 (ERK2) TT4TQBX MK01_HUMAN Inhibitor [2]
Glycogen synthase kinase-3 alpha (GSK-3A) TTRZQE3 GSK3A_HUMAN Inhibitor [1]
Glycogen synthase kinase-3 beta (GSK-3B) TTRSMW9 GSK3B_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
55 kDa erythrocyte membrane protein (MPP1) OTA2ENZQ EM55_HUMAN Gene/Protein Processing [3]
Alpha-fetoprotein (AFP) OT9GG3ZI FETA_HUMAN Gene/Protein Processing [3]
Apolipoprotein A-I (APOA1) OT5THARI APOA1_HUMAN Gene/Protein Processing [3]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Gene/Protein Processing [4]
Cytochrome P450 1A2 (CYP1A2) OTLLBX48 CP1A2_HUMAN Gene/Protein Processing [4]
Cytochrome P450 2E1 (CYP2E1) OTHQ17JG CP2E1_HUMAN Gene/Protein Processing [4]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Gene/Protein Processing [4]
Fibroblast growth factor 8 (FGF8) OTFU0IUW FGF8_HUMAN Gene/Protein Processing [3]
Glycogen synthase kinase-3 beta (GSK3B) OTL3L14B GSK3B_HUMAN Post-Translational Modifications [5]
Hepatocyte nuclear factor 3-alpha (FOXA1) OTEBY0TD FOXA1_HUMAN Gene/Protein Processing [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 4.9488 11.0518 0.7146 11.9092
EW-22 GDSC1 2.0459 3.9691 1.7114 18.2344
CHSA8926 GDSC1 2.2029 6.0394 0.9464 18.5332
NY GDSC1 2.8691 5.0232 2.0697 9.3498
ES1 GDSC1 2.9488 4.5995 2.3506 7.3274
EW-1 GDSC1 3.6323 5.7903 2.3359 5.3959
HuO-3N1 GDSC1 3.7291 6.292 2.161 6.2459
EW-7 GDSC1 4.0001 5.7248 2.6278 2.77
CAL-72 GDSC1 4.0187 12.3304 -0.6156 20.7748
CHSA0011 GDSC1; GDSC2 4.0679 6.8444 2.1369 5.5885
ES5 GDSC1; GDSC2 4.168 6.215 2.505 3.1672
SW1353 CTRP2 4.3087 7.1093 3.4884 10.6113
U-CH2 GDSC2 4.3127 6.1148 2.6393 2.1515
ES7 GDSC1 4.3131 7.2704 2.1001 5.2798
NOS-1 [Human HNSCC] GDSC1 4.4239 7.5511 2.0402 5.4087
TC-71 GDSC1 4.4347 6.2665 2.641 1.9547
HuO9 GDSC1 4.5103 6.9386 2.3818 3.2554
CADO-ES1 GDSC1 4.6052 7.162 2.3366 4.1646
U2OS GDSC1; GDSC2; CTRP2 4.654 5.9821 4.5819 11.3486
CHSA0108 GDSC1; GDSC2 4.6654 7.3772 2.2744 3.5927
CAL-78 GDSC1; CTRP2 4.7599 7.9186 4.0186 13.177
G-292 clone A141B1 GDSC1; CTRP2 4.7833 10.8092 2.6953 18.3481
A-673 GDSC1; CTRP2 4.8131 6.6622 4.5713 10.9048
EW-16 GDSC1 5.1532 10.415 1.1609 9.0102
ES6 GDSC1 5.2709 13.936 -0.4615 16.9636
EW-24 GDSC1 5.277 6.6912 2.8605 0.3025
EW-12 GDSC2 5.4377 7.1466 2.7576 0.4977
EW-18 GDSC1 5.6073 7.5059 2.6928 0.5949
SJSA-1 GDSC1; CTRP2 5.6514 7.297 4.5937 2.6551
TC71 CTRP2 5.7954 6.5925 5.656 4.0126
SaOS-2 GDSC1; CTRP2 5.8399 7.051 5.5056 4.487
SK-ES-1 GDSC1; CTRP2 5.8617 6.6245 5.7138 3.6072
ES4 GDSC1 5.8737 8.3719 2.4751 1.1492
H-EMC-SS GDSC1 5.974 12.2659 0.8197 9.239
Hs 888.T CTRP2 6.039 10.6773 3.9042 10.699
HOS GDSC1; CTRP2 6.2266 6.9809 5.91 1.9229
MHH-ES-1 GDSC1; GDSC2; CTRP2 6.2986 8.3171 5.3048 4.3163
EW-3 GDSC1 6.3146 8.2149 2.709 0.2684
EW-13 GDSC1 6.315 8.0956 2.7502 0.1999
SK-PN-DW GDSC1 6.348 8.2993 2.6917 0.2905
ES8 GDSC1 6.4033 8.0835 2.7851 0.1352
MG-63 GDSC1; CTRP2 6.9948 13.2053 3.4237 10.8607
Hs 822.T CTRP2 7.045 8.0169 5.9742 0.6056
EW-11 GDSC1 7.0774 9.1734 2.6515 0.1849
SK-N-MC CTRP2 8.0192 9.0909 5.9764 0.0985
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 218 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 3.4568 6.0711 3.2599 19.7513
MEC1 CTRP2 5.6715 6.4687 5.5672 4.7012
JM1 GDSC1; GDSC2; CTRP2 1.978 2.7683 1.978 28.9119
NU-DHL-1 CTRP2 0.9834 4.9026 0.8129 36.0607
ST486 GDSC1; CTRP2 0.9917 1.9837 0.9917 35.4767
MY-M12 GDSC1; GDSC2 1.0106 2.9296 0.8948 23.7914
KMS-21-BM CTRP2 1.0613 3.3946 1.0465 35.062
Reh GDSC1; CTRP2 1.17 2.1434 1.17 34.2898
NALM-6 GDSC1; CTRP2 1.612 2.6189 1.612 31.3478
CTV-1 GDSC1 1.8525 3.1244 1.7676 15.1865
WSU-DLCL2 GDSC1; CTRP2; CTRP1 1.9197 4.4345 1.8718 29.4604
Mino CTRP2 1.9228 2.313 1.9228 29.2794
RCH-ACV GDSC1; GDSC2; CTRP2 1.9972 3.4127 1.9956 28.7896
Kasumi-2 CTRP2 2.0464 3.1577 2.0462 28.4573
MC116 GDSC1; GDSC2; CTRP2 2.0617 4.3143 2.03 28.4611
P32/ISH GDSC1 2.1221 3.0405 2.0772 12.2705
BALL-1 GDSC1 2.1417 3.735 1.9014 13.1475
Kasumi-1 GDSC1; GDSC2 2.1534 3.6276 1.9518 12.8123
SEM CTRP2 2.2373 3.12 2.2373 27.186
SUP-B15 GDSC1; CTRP2 2.2697 3.2412 2.2696 26.9705
SU-DHL-5 GDSC1; CTRP1 2.3186 3.3229 2.3184 30.8769
MOLM-16 GDSC1; GDSC2; CTRP2; CTRP1 2.4218 3.8504 2.4186 25.9689
JeKo-1 GDSC1; GDSC2; CTRP2 2.4482 3.8199 2.4457 25.7907
MV4-11 GDSC1; CTRP2 2.4539 5.1029 2.3601 26.062
BE-13 GDSC1 2.4639 3.3337 2.3823 9.0403
SET-2 CTRP2 2.47 3.1964 2.47 25.6374
HEL GDSC1; GDSC2; CTRP2 2.4809 4.5757 2.3887 20.594
Peer CTRP2 2.529 4.1589 2.5201 25.2745
SUP-T1 GDSC1; CTRP2 2.5337 3.8783 2.5312 25.222
KMS-26 CTRP2 2.5649 4.3962 2.5467 25.0664
MHH-CALL-4 GDSC2; CTRP2 2.5781 4.0326 2.5735 24.933
ALL-SIL GDSC1 2.583 4.5 2.0428 10.538
Ri-1 CTRP2 2.5931 5.0098 2.5214 25.0603
SU-DHL-4 GDSC1; GDSC2; CTRP2; CTRP1 2.6013 5.1154 2.516 25.0525
697 GDSC1; CTRP2 2.6101 3.825 2.6088 24.7093
Pfeiffer CTRP2 2.6242 4.6817 2.5888 24.7298
BV-173 GDSC1; CTRP2 2.6416 3.82 2.6405 24.4991
KE-37 GDSC1; CTRP2 2.6867 3.5082 2.6866 24.1955
RS4;11 GDSC1; CTRP2 2.8015 6.1063 2.3232 19.8066
MEG-01 GDSC1 2.8106 5.6069 1.7296 11.6655
EoL-1 GDSC1; CTRP2 2.8137 4.4671 2.7996 23.397
SCC-3 GDSC1 2.8458 4.2851 0.8692 0.8018
TF-1 CTRP2 2.8667 3.4198 2.8667 22.9969
MOLT-16 GDSC1; CTRP2 2.8928 3.4972 2.8928 22.8236
A4/Fukuda GDSC1 2.8948 3.9425 2.6101 5.9244
SU-DHL-6 GDSC1; CTRP2 2.8999 6.4375 2.5552 23.9765
NCI-H929 GDSC1; CTRP2 2.9406 4.0729 2.9391 22.5101
A3/Kawakami GDSC1; CTRP2 2.9559 3.8912 2.9556 22.4046
OCI-M1 GDSC1; CTRP2 2.9584 3.692 2.9584 22.3865
DoHH2 GDSC1; GDSC2 2.97 4.5062 2.4159 6.848
HAL-01 GDSC1 3.101 4.4372 2.571 5.4378
L-363 GDSC1; CTRP2 3.1763 4.3541 3.1732 20.9467
GA-10 GDSC1 3.2287 6.7536 1.5278 11.5984
SU-DHL-8 GDSC1; CTRP2 3.2617 4.7879 3.245 20.4239
ALL-PO GDSC1 3.2634 6.2631 1.8022 9.7831
EM-2 GDSC1; CTRP2 3.3004 5.0304 3.2671 20.2224
IM-9 GDSC1 3.306 4.4609 2.7391 3.7362
P30/OHK GDSC1 3.3349 4.5962 2.6956 3.9281
MHH-PREB-1 GDSC1 3.3484 4.8039 2.6029 4.4756
GR-ST GDSC1 3.3498 4.9469 2.5326 4.917
LC4-1 GDSC1 3.3557 5.6035 2.2091 6.9469
BC-1 GDSC1 3.364 4.7525 2.6414 4.1874
KMS-11 GDSC1; GDSC2; CTRP2; CTRP1 3.3697 4.4624 3.3671 19.6579
KE-97 CTRP2 3.3773 5.0654 3.3447 19.7081
AMO1 GDSC1; CTRP2; CTRP1 3.4293 6.5246 3.1076 20.3823
NCO2 CTRP2 3.4432 5.6405 3.3366 19.5242
Jurkat GDSC1; CTRP2 3.4543 4.8586 3.3889 13.5557
MOLT-13 GDSC1 3.4739 4.9225 2.6445 4.8167
Karpas-231 GDSC1 3.4982 4.9307 2.6594 3.7094
JJN-3 GDSC1; CTRP2 3.5082 5.1377 3.4756 18.8369
KYO-1 CTRP2 3.5212 4.5163 3.5193 18.6471
CML-T1 GDSC1; CTRP2 3.5296 5.0372 3.5065 18.6623
HC-1 GDSC1 3.5416 5.2743 2.5222 4.4594
CMK GDSC1; CTRP2 3.5452 4.8807 3.5327 18.5231
BC-3 GDSC1; GDSC2 3.5478 5.3211 2.5038 4.559
JSC-1 GDSC1 3.5589 5.36 0.7605 0.6749
Farage GDSC1; GDSC2 3.582 5.8115 2.2867 5.8355
DB GDSC1; CTRP2 3.5911 5.8337 3.4594 18.6277
SUP-B8 GDSC1; GDSC2 3.6293 6.0556 2.2021 6.2443
EB1 CTRP2 3.6322 6.1599 3.4291 18.6076
NKM-1 GDSC1 3.653 8.0534 1.2261 12.2198
OCI-Ly7 GDSC2 3.6952 6.3364 2.1134 6.6308
DND-41 GDSC1; CTRP2 3.7344 5.5146 3.6705 17.4385
K-562 GDSC1; CTRP2 3.7412 5.6462 3.6571 17.4631
NU-DUL-1 GDSC1; GDSC2; CTRP2; CTRP1 3.7718 5.3202 3.7349 17.0973
PF-382 GDSC1; CTRP2 3.7747 5.2895 3.7413 17.066
Ki-JK CTRP2 3.7791 5.4514 3.727 17.1006
DG-75 GDSC1 3.8311 5.831 2.4623 4.1286
OCI-Ly3 CTRP2 3.8464 5.6878 3.7632 16.7601
Loucy GDSC1 3.89 6.0616 2.3918 4.4278
ATN-1 GDSC1 3.9285 6.8105 2.0537 6.424
TUR GDSC1 3.9373 5.5055 2.6905 2.5223
QIMR-WIL GDSC1; GDSC2 3.9531 6.8449 2.0548 6.3589
Ku812 GDSC1 3.9578 7.3981 1.7864 8.0038
OCI-Ly19 GDSC1; GDSC2; CTRP2 3.9655 5.9342 3.8448 16.099
HEL 92.1.7 CTRP2 3.9837 6.0315 3.8432 16.0477
VL51 GDSC1 3.9944 6.4974 2.2538 5.0388
RC-K8 GDSC1 3.9947 6.7437 2.1342 5.7721
CRO-AP2 GDSC1; GDSC2 4.0222 5.7552 2.6277 2.728
SU-DHL-1 GDSC1; GDSC2; CTRP2 4.0335 5.49 3.9928 15.3687
SU-DHL-10 GDSC1; CTRP2 4.041 5.9182 3.9302 15.5618
P12-Ichikawa GDSC1; CTRP2 4.0569 5.5592 4.0088 15.2385
KOPN-8 GDSC1 4.0616 7.4515 1.8365 7.4449
MM1.S CTRP2 4.0753 5.4693 4.0396 15.0735
CCRF-CEM GDSC1 4.0898 7.8141 1.6793 8.3388
MLMA GDSC1 4.0921 6.0071 2.5541 3.0248
KMS-12-BM GDSC1; CTRP2 4.1515 6.1784 3.9909 15.0036
MHH-CALL-3 CTRP2 4.1932 10.2018 2.4118 20.8831
MOLP-8 GDSC1 4.198 6.2946 2.4868 3.2166
MOLT-4 GDSC1 4.1983 6.1613 2.5491 2.8547
HPB-ALL CTRP2 4.237 5.2588 4.2266 13.9113
ROS-50 GDSC1; GDSC2 4.264 6.2673 2.5407 2.7849
WSU-NHL GDSC1 4.2648 6.6344 2.3701 3.7724
KMS-34 CTRP2 4.2653 5.1771 4.2595 13.7077
F-36P CTRP2 4.2754 6.509 4.0347 14.4694
RPMI-8866 GDSC1 4.2763 6.1629 2.596 2.4508
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 4.2851 6.2379 4.1215 14.126
L-540 GDSC1; CTRP2 4.2898 5.707 4.2368 13.7055
SKM-1 GDSC1; GDSC2; CTRP2; CTRP1 4.3553 5.9096 4.2725 13.3728
MHH-CALL-2 GDSC1 4.3885 6.2843 2.6069 2.7501
Ramos.2G6.4C10 GDSC1 4.3911 7.5016 2.0419 5.4658
CESS GDSC1 4.4632 6.5885 2.5132 2.6007
KMS-28BM CTRP2 4.4864 6.8075 4.1679 13.3564
U-937 CTRP2; CTRP1 4.4927 6.6124 4.2394 13.073
MOLM-6 CTRP2 4.5113 6.2785 4.3576 12.5868
RPMI-8402 GDSC1; CTRP2 4.5225 6.537 4.2955 12.7786
CA46 GDSC1; CTRP2 4.5272 6.4414 4.3294 12.6407
Daudi GDSC1; CTRP2 4.533 6.8092 4.2178 13.035
SUP-M2 GDSC1; CTRP2 4.5701 6.0232 4.4826 11.9607
Hs 611.T CTRP2 4.571 7.3875 4.0425 13.592
SK-MM-2 GDSC1; CTRP2 4.5755 8.9275 3.3805 16.1751
JVM-2 GDSC1 4.5857 7.3259 2.2495 3.8741
Sc-1 GDSC1 4.6029 6.1225 2.7903 1.0115
LP-1 GDSC1; GDSC2; CTRP2; CTRP1 4.6219 6.9763 4.2543 12.6426
MOLT-3 CTRP2 4.6256 6.441 4.4369 11.9541
KCL-22 GDSC1; CTRP2 4.6325 5.8547 4.5815 11.418
ARH-77 GDSC1 4.65 6.6237 2.6023 1.8511
YT GDSC1 4.6589 6.5882 2.6224 1.7386
AML-193 CTRP2 4.6721 6.3036 4.5264 11.4895
U266B1 GDSC1; CTRP2 4.6751 7.042 4.2871 12.3676
HDLM-2 GDSC1; CTRP2 4.684 6.7664 4.3959 11.9332
BL-70 CTRP2 4.6909 6.0326 4.6117 11.1278
SR GDSC1; CTRP2 4.7048 5.994 4.6346 11.0038
JVM-3 GDSC1; CTRP2 4.7132 6.5192 4.5087 11.4301
H9 GDSC1 4.7546 10.4501 0.8697 11.5038
Namalwa GDSC1; CTRP2 4.7671 6.7581 4.4888 11.3455
L-1236 GDSC1; CTRP2 4.7688 7.771 4.0915 12.8672
P31/FUJ GDSC1; CTRP2 4.7877 5.9955 4.7241 10.4293
JURL-MK1 GDSC1; CTRP2 4.8137 7.3102 4.3303 11.8167
KMS-20 CTRP2 4.8235 6.4239 4.6577 10.5563
ME1 GDSC1 4.8281 6.1687 2.8737 0.4978
M-07e CTRP2 4.8433 13.353 1.5091 22.486
GDM-1 GDSC1; CTRP2; CTRP1 4.8596 7.3508 4.3623 11.5679
OCI-AML-2 GDSC1; CTRP2 4.8641 6.3508 4.7229 10.1972
TK [Human B-cell lymphoma] GDSC1 4.8748 6.3255 2.8336 0.6023
CTB-1 GDSC1; GDSC2 4.8806 6.9814 2.5699 1.7161
PL21 CTRP2; CTRP1 4.9029 5.8045 4.8779 9.5291
DEL GDSC1; CTRP2 4.9449 5.4552 4.9437 9.1689
OCI-AML-3 GDSC1; CTRP2; CTRP1 4.9829 6.2033 4.8912 9.2298
HH [Human lymphoma] GDSC1; CTRP2 4.9871 6.5685 4.7911 9.581
HD-MY-Z CTRP2 5.0006 7.4018 4.489 10.6942
Toledo CTRP2 5.0039 9.0509 3.7478 13.6446
MOLM-13 GDSC1; CTRP2 5.0476 6.6204 4.8396 9.2241
RL GDSC1; GDSC2; CTRP2 5.0662 7.7195 4.4205 10.7905
MN-60 GDSC1 5.0772 7.5232 2.4408 2.0981
MOLP-2 CTRP2 5.1045 6.9371 4.7862 9.2624
KM-H2 GDSC1; CTRP2 5.1449 7.3756 4.6505 9.6777
HT GDSC1; GDSC2; CTRP2 5.164 6.5775 4.9803 8.3617
EJM GDSC1; CTRP2; CTRP1 5.17 7.2732 4.72 9.3389
SUP-T11 CTRP2 5.2114 6.0866 5.1652 7.5494
WIL2 NS GDSC1 5.2928 6.7772 2.8356 0.357
KY821 GDSC1 5.3134 6.9843 2.7676 0.5369
SU-DHL-16 GDSC1; GDSC2 5.3278 6.5223 2.9384 0.1346
EB2 GDSC1 5.3385 7.0364 2.7584 0.5503
ML-2 GDSC1 5.3606 6.877 2.8258 0.352
RPMI-8226 GDSC1; CTRP2; CTRP1 5.3674 6.9063 5.0779 7.4154
LAMA-84 GDSC1 5.4044 7.1737 2.734 0.5867
OPM-2 GDSC1; CTRP2 5.4822 6.5954 5.3186 6.1773
Jiyoye GDSC1 5.5151 7.6174 2.6116 0.924
MOTN-1 CTRP2 5.5515 6.6349 5.3788 5.7526
VAL GDSC1 5.5563 7.1362 2.8076 0.3156
KG-1 GDSC1 5.6244 7.5226 2.6936 0.5832
KO52 CTRP2 5.6384 6.1775 5.6099 4.6471
P3HR-1 CTRP2 5.6412 11.6956 3.0487 15.0167
OCI-AML-5 GDSC1; CTRP2 5.6511 6.1674 5.6255 4.5524
EHEB GDSC1; CTRP2 5.6948 7.4919 4.5299 2.8629
THP-1 GDSC1; GDSC2; CTRP1 5.7172 6.3821 5.6446 4.9605
Mono-Mac-1 CTRP2 5.7248 6.7435 5.5211 4.726
L-428 GDSC1; CTRP2 5.7445 6.6007 5.5985 4.3744
KMS-18 CTRP2 5.7588 6.4309 5.6745 4.0479
NK-92MI GDSC1; GDSC2 5.7999 7.3844 2.8106 0.2292
Hs 445 GDSC1 5.8087 7.2441 2.8619 0.1441
Karpas-1106P GDSC1 5.8358 7.2182 2.8801 0.1433
REC-1 CTRP2 5.836 7.3471 5.3639 5.0701
ME1 CTRP2 5.8602 6.3964 5.7959 3.3009
SIG-M5 GDSC1; GDSC2; CTRP2 5.8675 6.2677 5.8397 3.1206
HL-60 GDSC1; CTRP2 5.9623 6.6131 5.8242 2.9063
Granta-519 GDSC1; CTRP2 6.0824 7.0147 5.7602 2.8654
NOMO-1 GDSC1; CTRP2; CTRP1 6.0839 7.986 5.2841 4.8399
Ci-1 CTRP2 6.1202 6.6462 5.9715 1.913
U-698-M GDSC1 6.1613 7.8827 2.7685 0.2069
BONNA-12 GDSC2 6.1616 8.1353 2.6805 0.3741
OCI-Ly10 CTRP2; CTRP1 6.3134 8.3048 5.3234 4.2096
Karpas-45 GDSC1 6.3394 7.9793 2.7981 0.1302
Mono-Mac-6 GDSC1 6.3467 8.829 2.5007 0.7535
KMOE-2 GDSC1 6.5311 8.4651 2.7004 0.2275
Karpas-620 GDSC1; CTRP2 6.5774 8.625 5.3757 3.5072
PL-21 GDSC1; GDSC2 6.9593 8.9245 2.6943 0.1525
BL-41 GDSC1; CTRP2 6.9766 14.4597 2.7849 13.4119
KHM-1B CTRP2 6.9904 9.7287 5.1384 3.8194
RPMI-6666 GDSC1; CTRP2 7.2398 8.7246 5.7718 1.029
KMS-27 CTRP2 7.54 9.5689 5.566 1.4561
NB4 GDSC1; GDSC2; CTRP2 7.6573 9.193 5.7876 0.6421
KMM-1 CTRP2 7.687 11.5471 4.7407 4.422
Raji GDSC1; CTRP2 7.9327 9.3422 5.8518 0.3333
Karpas-299 GDSC1; CTRP2 8.0492 9.6366 5.7888 0.4213
Karpas-422 GDSC1; CTRP2 8.1786 9.6752 5.8279 0.2875
SUP-HD1 GDSC1; CTRP2 9.0928 11.1636 5.6441 0.3232
⏷ Show the Full List of 218 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 5.0945 6.8189 4.8201 9.162
TE15 CTRP2 5.5647 8.5085 4.5476 9.0518
TE-8 GDSC1 3.7629 10.6656 0.0108 18.5875
KYSE-270 GDSC1 4.4175 7.7979 1.918 6.1507
TE-6 GDSC1; CTRP2 4.6312 5.8507 4.3786 5.9271
T.T GDSC1 4.7004 9.2056 1.4345 8.4051
OE21 GDSC1; CTRP2 5.1821 7.6737 4.5592 9.9403
TE-10 GDSC1; GDSC2; CTRP2 5.2054 7.6053 4.6133 9.6656
TE-5 GDSC1; CTRP2 5.2321 7.6 4.643 9.4788
KYSE-410 GDSC1; CTRP2 5.5451 8.212 4.6711 8.5916
OE33 GDSC1; CTRP2 5.5557 9.3231 4.1431 10.7401
EC-GI-10 GDSC1; CTRP2 5.9429 7.4189 5.4326 4.5358
KYSE-140 GDSC1; CTRP2 5.9878 9.6991 4.3474 8.9572
KYSE-30 CTRP2 5.9964 7.6051 5.3923 4.5806
KYSE-150 GDSC1; CTRP2 6.0041 12.7257 2.8515 15.0324
TE-4 GDSC1; CTRP2 6.0159 7.0928 5.659 3.4359
KYSE-510 GDSC1; GDSC2; CTRP2 6.0602 6.5961 5.9331 2.2196
TE-9 GDSC1; CTRP2 6.0623 8.6728 4.9237 6.3922
TE-14 CTRP2 6.0823 6.9847 5.7745 2.8067
TE-1 GDSC1; CTRP2 6.1244 8.995 4.8174 6.7092
TE-15 GDSC1 6.1561 8.3605 2.5972 0.5799
KYSE-70 GDSC1; CTRP2 6.6898 8.1499 5.6934 2.0089
KYSE-520 GDSC1; CTRP2 7.7667 16.7491 2.258 13.9945
OE19 GDSC1; CTRP2 8.0773 14.362 3.6541 8.1827
KYSE-450 GDSC1; CTRP2 8.2045 9.4944 5.9032 0.1551
COLO 680N GDSC1; CTRP2 8.2924 10.3034 5.6358 0.6694
TE-11 GDSC1; GDSC2; CTRP2 8.3776 10.1842 5.719 0.4316
KYSE-180 GDSC1; CTRP2 8.4001 10.3583 5.6619 0.5498
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 9.1896 11.0263 5.7291 0.1772
AsPC-1 GDSC1; CTRP2 3.8281 5.4877 3.7745 16.7797
KP-1N GDSC1 4.496 7.1706 2.2658 3.9431
HuP-T4 GDSC1; CTRP2 4.5754 6.2434 4.4367 12.1071
PL4 GDSC1 4.7077 7.3133 2.3286 3.2199
BxPC-3 GDSC1; CTRP2 4.9646 11.0047 2.7715 17.6247
KP-3 GDSC1; CTRP2 5.1206 7.854 4.4163 10.6666
HPAC GDSC1; CTRP2 5.1468 6.4173 5.0122 8.2951
SU.86.86 GDSC1; CTRP2 5.2272 6.7083 5.0032 8.093
Hs 766T GDSC1; CTRP2 5.4795 13.2789 2.1187 18.9145
MIA PaCa-2 GDSC1; CTRP2 5.5031 6.6323 5.3278 6.0827
SNU-213 CTRP2 5.583 7.0526 4.6633 2.4654
L3.3 CTRP2 5.608 6.4493 5.5047 5.1187
Panc 03.27 GDSC1; CTRP2 5.6751 10.4011 3.7211 12.2188
KP-2 GDSC1; CTRP2 5.7066 7.9147 4.9686 6.9926
PK-59 CTRP2 5.7243 7.9882 4.9502 7.0269
MZ-PC-1 GDSC1; GDSC2 5.7265 8.1622 2.4919 1.2036
Panc 05.04 CTRP2 5.7288 9.2781 4.3245 9.6048
SW1990 GDSC1; CTRP2 5.811 9.4098 4.3339 9.3874
YAPC GDSC1; CTRP2 5.863 6.8145 5.635 3.9122
PaTu 8988s CTRP2 5.9876 10.674 3.8614 10.9815
Panc 08.13 GDSC1; CTRP2 6.0105 7.5216 5.4462 4.3255
Capan-1 GDSC1; CTRP2 6.0221 8.6465 4.9012 6.5703
Panc 10.05 GDSC1; CTRP2 6.0576 7.5591 5.4713 4.7545
KP-4 GDSC1; CTRP2 6.0633 6.8303 5.8295 2.6272
Panc 04.03 GDSC1; CTRP2 6.0719 7.0765 5.7203 3.0536
DAN-G GDSC1; CTRP2 6.0982 6.8949 5.8328 2.5302
PSN1 GDSC1; CTRP2 6.1915 7.1959 5.772 2.5739
Capan-2 GDSC1; CTRP2 6.2465 7.3047 5.7664 2.4825
HuP-T3 GDSC1; CTRP2 6.2852 7.391 5.7565 2.446
PaTu 8902 GDSC1; CTRP2 6.6315 7.896 5.7756 1.7617
TCC-Pan2 CTRP2 6.6593 8.2908 5.6026 2.4291
SNU-410 CTRP2 6.7938 9.6399 5.0379 4.5477
QGP-1 GDSC1; GDSC2; CTRP2 7.0493 8.3116 4.9097 0.1977
PaTu 8988t GDSC1; CTRP2 8.0819 9.1666 5.9728 0.0917
SUIT-2 GDSC1; CTRP2 8.2899 9.6896 5.866 0.1888
PK-45H CTRP2 8.4436 12.321 4.8517 3.0853
CFPAC-1 GDSC1; CTRP2 8.7205 10.4357 5.763 0.2351
HPAF-II GDSC1; CTRP2 8.905 10.6195 5.7669 0.1862
Panc 02.03 GDSC1; CTRP2 9.1898 10.832 5.7959 0.1061
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 74 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 6.2891 15.9112 1.5 19.3772
WM278 GDSC1 2.2702 5.0354 1.4844 15.0906
RPMI-7951 GDSC1; CTRP2 2.8071 5.0538 2.7434 23.609
SK-MEL-2 GDSC1; CTRP2 2.9573 6.3976 2.6291 23.5374
IST-MEL1 GDSC1 3.1953 5.4444 2.1534 7.7736
LB373-MEL-D GDSC1; GDSC2 3.4648 5.6008 2.2992 6.0708
VMRC-MELG GDSC1; GDSC2 3.5365 6.4185 1.9487 8.0845
COLO 783 GDSC1; GDSC2 3.6059 5.4795 2.4697 4.6241
Hs 938.T GDSC1; GDSC2 3.6465 6.0681 2.2091 6.1555
GAK GDSC1 3.8656 5.828 2.488 3.8929
LOX-IMVI GDSC1; CTRP2 3.9005 10.8893 1.8023 23.8314
WM793 GDSC1; CTRP2 4.0031 6.9996 3.5785 16.9552
Hs 294T CTRP2 4.094 5.8889 3.9936 15.1728
HMV-II GDSC1 4.1456 10.2678 0.5093 14.9754
WM35 GDSC1 4.2273 13.7693 -1.1677 22.4719
WM1552C GDSC1 4.2711 6.1287 2.6085 2.3896
CP50-MEL-B GDSC1; GDSC2 4.2765 6.0917 2.6285 2.2696
CP66-MEL GDSC1; GDSC2 4.2885 5.9888 2.6818 1.9581
COLO 679 GDSC1 4.3269 5.9902 2.703 1.7864
A101D GDSC1; CTRP2 4.3807 7.6944 3.7177 15.3657
A-375 GDSC1; GDSC2; CTRP2; CTRP1 4.4087 7.2777 3.9128 14.5396
HT-144 GDSC1; CTRP2 4.6537 7.96 3.8911 13.958
G-mel GDSC1; GDSC2 4.6765 6.2358 2.7793 0.9846
MDA-MB-435S CTRP2 4.7356 9.0917 3.4646 15.4396
MZ-MEL-2 GDSC1; GDSC2 4.7634 10.0297 1.0802 10.3043
DJM-1 GDSC1; GDSC2 4.7968 7.03 2.5049 2.1466
Hs 940.T GDSC1; GDSC2; CTRP2 5.1776 12.2077 2.3783 21.2404
451Lu GDSC1; GDSC2 5.297 6.9368 2.7786 0.5129
LB2518-MEL GDSC1; GDSC2 5.3389 12.4848 0.2931 13.2358
Hs 852.T CTRP2 5.4914 8.3948 4.5321 9.2872
WM115 GDSC1; CTRP2 5.5056 6.587 5.3468 6.0043
SH-4 GDSC1 5.5146 7.3057 2.7297 0.5373
IPC-298 GDSC1; GDSC2; CTRP2 5.5902 7.4455 5.075 6.8425
MZ-MEL-7 GDSC1; GDSC2 5.5947 7.0164 2.8638 0.1908
A-388 GDSC1; GDSC2 5.6295 7.5021 2.7032 0.5521
SK-MEL-31 GDSC1; GDSC2; CTRP2 5.6429 9.2497 4.2597 10.0629
RVH-421 GDSC1; GDSC2; CTRP2 5.6736 6.2413 5.6347 4.4493
MMAc-SF GDSC1; GDSC2 5.7358 7.5819 2.7161 0.4636
IGR-1 GDSC1; CTRP2 5.7839 8.4824 4.7661 7.6507
IGR-39 CTRP2 5.7925 11.1881 3.4347 13.1407
WM1799 CTRP2 5.7984 6.5213 5.6859 3.8906
A-431 GDSC1; GDSC2 5.8073 7.3775 2.8156 0.218
WM88 CTRP2 5.8083 6.4086 5.7356 3.6765
Hs 944.T CTRP2 5.8144 6.5598 5.6888 3.8343
MeWo GDSC1; CTRP2 5.8631 6.394 5.7999 3.2779
SK-MEL-5 GDSC1; GDSC2; CTRP2; CTRP1 5.9064 6.6669 5.7432 3.3722
UACC-62 GDSC1; CTRP2 5.9261 6.4143 5.8616 2.8647
Mel JuSo GDSC1; CTRP2 5.9431 6.6598 5.7845 3.1127
WM266-4 CTRP2 5.9685 6.3334 5.933 2.4769
CHL-1 GDSC1 6.0087 7.4859 2.8498 0.1229
IGR-37 GDSC1; CTRP2 6.0324 6.5898 5.9071 2.3948
SK-MEL-24 GDSC1; CTRP2 6.0327 6.6143 5.8969 2.4343
Hs 895.T CTRP2 6.0373 8.7884 4.8441 6.7775
G-361 GDSC1; CTRP2 6.0672 7.8256 5.3485 4.6068
COLO 792 GDSC1; CTRP2 6.1765 9.9526 4.384 8.421
CJM [Human melanoma] CTRP2 6.2401 7.0906 5.8675 2.0722
WM983B CTRP2 6.2663 11.4963 3.6882 11.138
Hs 839.T CTRP2 6.3965 7.4118 5.8378 1.8935
UACC-257 GDSC1; CTRP2 6.4049 7.5635 5.7689 2.1674
WT2-iPS GDSC1; GDSC2; CTRP2 6.4394 7.2755 5.9392 1.3944
M14 GDSC1 6.4754 19.4072 -2.2681 21.1713
SK-MEL-3 GDSC1; GDSC2; CTRP2 6.7305 8.0044 5.792 1.5501
SK-MEL-28 GDSC1; GDSC2; CTRP2; CTRP1 6.7664 8.4504 5.6015 2.2684
SK-MEL-30 GDSC1; GDSC2; CTRP2 6.8406 8.2744 5.7367 1.6187
Hs 936.T CTRP2 6.8571 8.3641 5.705 1.7222
HMCB CTRP2 7.6221 8.9786 5.8575 0.472
Mel Ho GDSC1; GDSC2; CTRP2 7.8814 9.7153 5.6814 0.7974
A2058 GDSC1; CTRP2 8.0802 8.966 6.0399 0.034
SK-MEL-1 GDSC1; CTRP2; CTRP1 8.2966 9.6611 5.8787 0.1685
K029AX CTRP2 8.369 9.6206 5.9193 0.1028
COLO 800 GDSC1; GDSC2; CTRP2 8.4125 10.7153 5.5265 0.8897
COLO 829 GDSC1; CTRP2 9.5019 25.6253 -0.8248 20.4839
Hs 688(A).T CTRP2 11.4841 34.5218 -3.7416 23.7858
EquiPSC Line K2 GDSC1; GDSC2 5.5492 9.5948 1.7897 4.7986
⏷ Show the Full List of 74 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FLO-1 GDSC1 2.889 11.1057 -0.9363 29.3813
SK-GT-4 GDSC1 3.8641 7.0823 1.8722 9.5602
KYAE-1 GDSC1 4.1373 7.3469 1.9419 8.2183
KYSE-50 GDSC1 4.2109 7.2103 2.0594 5.7435
KYSE-220 GDSC1 4.2156 6.2443 2.5214 2.983
ESO-26 GDSC1 4.9433 6.7045 2.715 1.2448
ESO-51 GDSC1 5.3185 7.9714 2.3747 2.6388
OACP4 C GDSC1 5.6186 7.9873 2.5125 1.5115
OACM5.1 C GDSC1 5.7861 9.302 2.0498 3.8562
HCE-4 GDSC1; GDSC2 5.8813 7.5868 2.7697 0.2828
TE-12 GDSC1; GDSC2 6.2643 8.8298 2.4665 0.9065
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 5.8632 7.9537 2.6301 0.6386
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB69 GDSC1 1.406 2.6752 0.7377 4.6996
SJNB-13 GDSC1 2.659 3.5719 2.5175 7.4222
SJNB-14 GDSC1 3.1794 5.9934 1.8657 9.6362
KP-N-YS GDSC1; GDSC2 3.2199 4.6501 2.571 5.0595
GOTO GDSC1 3.2471 4.9379 2.4508 5.7369
NH-12 GDSC1 3.3573 5.2511 2.3867 5.8187
SJNB-10 GDSC1 3.4285 5.0672 2.5364 4.6718
SJNB-7 GDSC1 3.517 5.4765 2.4026 5.2769
MHH-NB-11 GDSC1; GDSC2; CTRP2 3.576 6.1092 3.3805 18.9542
IMR-32 CTRP2 3.6546 5.4394 3.5958 17.9521
SK-N-MC-IXC GDSC1; GDSC2 3.7495 5.8655 2.3865 4.789
GI-ME-N GDSC1 3.8095 6.2272 2.2529 5.4751
KP-N-SI9s CTRP2 3.96 5.4899 3.9146 15.8739
SJNB-5 GDSC1; GDSC2 4.0265 6.0171 2.5066 3.4369
IMR-5 GDSC1 4.1398 6.0782 2.5512 2.9514
SK-N-DZ GDSC1; CTRP2 4.1418 7.0055 3.7263 16.0026
SJNB-17 GDSC1; GDSC2 4.2184 7.5222 1.9139 6.6099
Kelly GDSC1; CTRP2 4.2916 5.5987 4.2536 13.6419
CHP-212 GDSC1; CTRP2 4.3855 6.4882 4.1609 13.6795
TGW GDSC1 4.6451 6.556 2.629 1.724
SK-N-SH GDSC1; CTRP2 4.7954 7.678 4.1587 12.5334
SiMa GDSC1; CTRP2 4.9594 7.6556 4.3384 11.394
CHP-126 GDSC1; GDSC2 5.1198 6.7748 2.766 0.6646
SJNB-6 GDSC1; GDSC2 5.4432 11.8685 0.661 11.1191
NB(TU)1 GDSC1 5.4439 7.1231 2.7688 0.4631
NB1 GDSC1; CTRP2 5.5944 9.8366 3.9267 11.5474
LA-N-6 GDSC1; GDSC2 5.5972 7.3031 2.7633 0.4051
KP-N-RT-BM-1 GDSC2 5.8074 7.9901 2.5935 0.7849
NH-6 CTRP2 5.8728 7.2647 5.4387 4.6767
SK-N-AS GDSC1; CTRP2 5.9424 6.7691 5.7363 3.3048
SK-N-BE(2) CTRP2 5.9477 6.791 5.7319 3.8209
SK-N-BE(2)-M17 GDSC1 6.2216 8.0997 2.7152 0.2837
SJNB-12 GDSC1 6.5625 9.6626 2.2747 1.3557
SK-N-FI GDSC1; CTRP2 7.0389 10.288 4.9 4.7221
KP-N-YN GDSC1; CTRP2 8.927 10.6171 5.7759 0.1702
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 3.247 9.5015 1.7719 25.7212
HuH-28 CTRP2 4.6047 7.2158 4.1457 13.1034
SNU-308 CTRP2 5.7547 8.3452 4.8059 7.5515
HuCC-T1 GDSC1; CTRP2 6.1314 7.2627 5.6847 3.0674
SNU-869 CTRP2 6.1817 6.8954 5.9113 2.0154
SNU-478 CTRP2 7.054 9.9739 5.0643 4.0258
SNU-1196 CTRP2 8.5086 10.0768 5.8107 0.2169
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1187 GDSC1 2.3229 3.5124 2.1743 10.8213
UACC-812 GDSC1 3.3537 5.0087 0.8079 0.6415
Hs 578T GDSC1 3.5397 6.3033 2.0086 7.699
OCUB-M GDSC1 3.7604 5.4573 2.594 3.4793
HCC2218 GDSC1; GDSC2; CTRP2 3.7656 6.4446 3.4977 17.9543
CAL-120 GDSC1 3.8411 6.9447 1.9229 7.4491
HCC1569 GDSC1; GDSC2 4.078 7.6017 1.7748 7.7837
HCC1599 GDSC1; GDSC2 4.0935 6.5276 2.3076 4.4942
MCF-7 GDSC1; CTRP2; CTRP1 4.3828 7.7741 3.6872 15.4779
MDA-MB-330 GDSC1; GDSC2 4.5309 7.2724 2.2403 4.0262
MDA-MB-157 GDSC1; CTRP2 4.569 6.7136 4.2893 12.6643
MFM-223 GDSC1 4.6765 7.0289 2.4385 2.6699
COLO 824 GDSC1 4.6947 9.3761 1.3485 8.918
Evsa-T GDSC1 4.6979 6.1398 2.8279 0.763
HCC2157 GDSC1 4.7167 6.517 2.6826 1.3764
HCC70 GDSC1 4.7229 6.8269 2.5533 2.0009
AU565 GDSC1; CTRP2 4.7315 6.8701 4.4108 13.5581
MDA-MB-436 GDSC1 4.8832 6.7695 2.6599 1.2952
MRK-nu-1 GDSC1 5.0343 6.4968 2.8356 0.4914
BT-483 GDSC1 5.2102 6.7667 2.8067 0.478
HCC1395 GDSC1; CTRP2 5.5943 9.7069 3.9905 11.2842
HCC1954 GDSC1; CTRP2 5.6307 9.431 4.1595 10.5051
HCC1143 GDSC1; CTRP2 5.667 7.1922 5.2673 5.8782
CAL-85-1 GDSC1; CTRP2 5.7266 8.4997 4.7043 8.0353
DU4475 GDSC1; CTRP2 5.7941 6.3601 5.735 3.7211
MDA-MB-175-VII GDSC1 5.8213 7.7397 2.6921 0.4867
SK-BR-3 CTRP2 5.839 6.8879 5.5781 4.1997
EFM-19 GDSC1 5.8576 8.3305 2.4842 1.1281
MDA-MB-453 GDSC1; CTRP2 5.9095 8.5479 4.849 7.0294
BT-20 GDSC1; CTRP2 5.9509 6.5411 5.8416 2.8698
HCC1500 GDSC1; CTRP2 6.0652 6.7526 5.8677 2.468
MDA-MB-231 GDSC1; CTRP2 6.0674 8.0821 5.2217 5.1358
HCC1428 GDSC1; CTRP2 6.308 7.1318 5.9054 1.7763
UACC-893 GDSC1; GDSC2 6.3707 8.362 2.6782 0.3093
ZR-75-1 CTRP2 6.3731 7.8907 5.5798 3.0194
HCC1419 GDSC1; CTRP2 6.4212 8.336 5.3964 3.6993
MDA-MB-415 GDSC1; CTRP2 6.4272 7.5692 5.7837 2.3849
HDQ-P1 GDSC1; CTRP2 6.4278 10.2169 4.462 7.607
MDA-MB-361 GDSC1; CTRP2 6.4527 7.6519 5.7625 2.1087
HCC1937 GDSC1; CTRP2 6.4869 9.6705 4.7831 6.1507
BT-474 GDSC1; CTRP2 6.5148 7.7081 5.7823 1.9203
T-47D GDSC1; CTRP2 6.5543 7.9012 5.7166 2.1277
BT-549 GDSC1; CTRP2 6.622 13.2354 3.112 12.7891
YMB-1-E GDSC2 6.6291 8.4213 2.7495 0.1407
ZR-75-30 GDSC1; CTRP2 6.7108 9.0336 5.2749 3.7013
Hs 578Bst CTRP2 7.0059 11.7146 4.1723 7.7818
CAL-51 GDSC1; CTRP2 7.0293 9.0363 5.4993 2.3047
EFM-192A GDSC1; CTRP2 7.0828 11.7526 4.2117 7.4898
CAL-148 GDSC1; CTRP2 7.6761 8.9374 5.8975 0.345
HMC-1-8 CTRP2 7.7276 8.7524 5.9873 0.1489
HCC1806 GDSC1; CTRP2 7.8646 10.965 5.1253 2.7143
CAMA-1 GDSC1; CTRP2 8.0328 9.4425 4.8725 0.0664
HCC38 GDSC1; CTRP2 8.0599 12.6525 4.4614 5.0238
JIMT-1 GDSC1; CTRP2 8.1518 10.2533 5.5908 0.8765
HCC202 GDSC1; CTRP2 8.4072 10.7366 5.5154 0.9239
MDA-MB-468 GDSC1; CTRP2 8.7521 10.1785 5.8643 0.1011
BT 416 CTRP2 2.5659 3.3614 2.5659 24.9988
BT 428 CTRP2 4.611 7.0279 4.2236 12.7894
BT 145 CTRP2 5.7471 6.3595 5.6839 4.048
BT 228 CTRP2 5.8986 7.9291 5.1431 5.8318
BT 231 CTRP2 6.0312 6.8173 5.8039 2.8095
BT 139 CTRP2 6.054 6.8384 5.8166 2.7023
BT 504 CTRP2 6.1365 6.8268 5.9021 2.1562
BT 172 CTRP2 6.1933 7.2754 5.7342 2.7279
BT 245 CTRP2 6.2205 7.2168 5.7874 2.4481
BT 422 CTRP2 6.2575 6.9067 5.9742 1.5893
BT 232 CTRP2 6.2672 7.0384 5.9171 1.8084
BT 187 CTRP2 6.3005 7.2627 5.8335 2.0926
BT147 CTRP2 6.3382 7.6403 5.6762 2.6802
BT 330 CTRP2 6.3624 7.3368 5.8478 1.9145
BT 248 CTRP2 6.3636 7.7066 5.664 2.6833
BT 179 CTRP2 6.4073 7.4291 5.8378 1.8742
BT 482 CTRP2 6.5114 7.5447 5.8603 1.6023
BT 328 CTRP2 6.5527 7.6694 5.8295 1.663
BT 359 CTRP2 6.5974 8.0151 5.6926 2.1568
BT 440 CTRP2 6.6149 9.8015 4.8199 5.7646
BT 286 CTRP2 6.6493 8.1106 5.6836 2.1113
BT 340 CTRP2 6.7235 8.0486 5.766 1.6645
BT 333 CTRP2 6.7273 7.7133 5.9281 1.0159
BT 216 CTRP2 6.7471 9.143 5.2482 3.7526
BT 159 CTRP2 6.9313 8.4501 5.7127 1.5942
BT 131 CTRP2 7.0607 8.5445 5.7493 1.2983
BT 320 CTRP2 7.1462 8.3532 5.8831 0.7361
BT 498 CTRP2 7.4815 8.494 5.9843 0.2381
BT 444 CTRP2 7.5064 8.7768 5.885 0.4667
BT 271 CTRP2 7.5463 9.2133 5.724 0.917
BT164 CTRP2 7.8754 8.9125 5.9861 0.1148
BT 112 CTRP2 7.9333 9.4134 5.8249 0.3924
BT 239 CTRP2 8.0315 9.4135 5.8655 0.2676
BT 224 CTRP2 8.2486 10.7933 5.4143 1.3374
⏷ Show the Full List of 90 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 8.2492 9.3658 5.964 0.0754
Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GI-1 GDSC1 2.2606 4.6844 1.6344 14.228
PFSK-1 GDSC1 2.5383 5.2492 0.2845 4.9984
KINGS-1 GDSC1 2.9518 4.5986 2.3539 7.297
LN-229 GDSC1; CTRP2; CTRP1 3.012 7.811 2.2164 24.8495
D-566MG GDSC1; GDSC2 3.0479 6.7294 1.3847 13.0335
MOG-G-CCM GDSC1 3.0559 4.5413 2.4785 6.1674
SNU-466 CTRP2 3.1882 5.448 3.0949 21.1747
H4 GDSC1 3.4106 6.5637 1.7743 9.5303
D-247MG GDSC1; GDSC2 3.439 5.6654 2.2463 6.4767
D-263MG GDSC1 3.4606 5.0479 2.5716 4.3624
D-423MG GDSC1; GDSC2 3.5171 6.1125 2.0858 7.2745
D-542MG GDSC1; GDSC2 3.5265 5.51 2.3934 5.3101
D-245MG GDSC2 3.814 6.4984 2.1228 6.2735
KS-1 [Human Krukenberg tumour] GDSC1 3.8763 6.8805 1.9809 7.0022
MOG-G-UVW GDSC1 4.0008 9.8773 0.5914 14.9147
LN-405 GDSC1 4.0897 5.7327 2.6804 2.2973
M059J GDSC1 4.1306 9.0359 1.1077 11.6567
D-502MG GDSC1; GDSC2 4.1312 5.8682 2.6434 2.4349
LN-18 GDSC1; CTRP2 4.1446 5.3345 4.1255 14.5559
SF539 GDSC1; CTRP2 4.1467 7.042 3.7186 16.0172
LNZTA3WT4 GDSC1 4.3582 6.2742 2.5938 2.3273
KNS-60 CTRP2 4.3649 6.6433 3.7585 9.2974
D-336MG GDSC1; GDSC2 4.5335 8.62 1.602 7.7841
YH-13 GDSC1; CTRP2 4.8563 8.006 4.0794 12.6857
SK-MG-1 GDSC1 4.9584 9.3346 1.5456 7.2246
Daoy GDSC1; CTRP2 5.0433 7.2377 4.6018 10.1403
M059K CTRP2 5.0547 8.4264 4.0895 12.1422
SF268 GDSC1; CTRP2 5.1133 8.5036 4.1117 11.9077
Hs 683 GDSC1; GDSC2; CTRP2 5.1323 7.4212 4.618 9.8387
GaMG GDSC1; CTRP2 5.1511 8.0804 4.3447 10.8759
KALS-1 GDSC1; CTRP2 5.1857 8.3895 4.2364 11.2261
KNS-81-FD GDSC1; GDSC2 5.2912 7.4049 2.5949 1.1722
SNU-1105 CTRP2 5.3105 8.7074 3.6196 7.6807
42-MG-BA GDSC1; CTRP2 5.4027 11.7891 2.789 16.5584
D283 Med GDSC1; CTRP2 5.4358 6.7976 5.1933 6.7833
SNU-201 CTRP2 5.4517 9.5163 3.952 11.7621
SNB-75 GDSC1; GDSC2; CTRP2 5.6469 7.8081 4.9618 7.1621
DK-MG GDSC1; CTRP2 5.6505 10.2842 3.7568 12.1251
AM-38 GDSC1 5.6595 7.6538 2.6589 0.668
TM-31 CTRP2 5.7158 8.8915 4.5026 8.8946
Onda 10 GDSC1; GDSC2 5.7837 8.2242 2.4931 1.1529
CAS-1 GDSC1; CTRP2 5.8419 8.4529 4.834 7.2402
SW1088 GDSC1; CTRP2 5.8579 7.914 5.1124 6.0509
Onda 11 GDSC1; GDSC2 5.8585 8.8444 2.2788 1.9594
D-392MG GDSC1 5.8765 15.8254 -0.95 17.6862
Becker GDSC1; CTRP2 5.9202 9.6586 4.308 9.2631
U-87MG ATCC GDSC1; CTRP2 5.9439 7.4326 4.7289 1.6233
SW1783 GDSC1; CTRP2 6.0462 11.1116 3.6936 11.5549
U-118MG GDSC1; CTRP2 6.1132 8.1357 5.2357 4.9807
YKG-1 GDSC1; GDSC2; CTRP2 6.3009 7.1492 5.8907 1.8518
KG-1-C CTRP2 6.3021 7.1385 5.897 1.823
A-172 GDSC1; CTRP2 6.3488 11.6986 3.6559 11.1101
U-251MG GDSC1; CTRP2 6.3927 7.641 5.7205 2.3925
SNU-738 CTRP2 6.3995 7.4711 5.8106 2.0021
KNS-81 CTRP2 6.4053 7.8291 5.6367 2.7207
SNU-489 CTRP2 6.5584 8.4701 5.438 3.2804
DBTRG-05MG GDSC1; CTRP2 6.5692 8.0061 5.6759 2.2717
SNU-626 CTRP2 7.0573 9.3396 5.3732 2.7694
GB-1 GDSC1; CTRP2 7.0928 9.4813 5.3293 2.8952
NMC-G1 GDSC1; GDSC2; CTRP2 7.1319 9.4781 5.3571 2.7303
KNS-42 GDSC1; GDSC2; CTRP2 7.1922 10.6203 4.8477 4.7
T98G GDSC1; CTRP2 7.4744 14.362 3.2173 10.8576
SF126 GDSC1; GDSC2; CTRP2 7.5443 11.553 4.6417 5.0163
SF295 GDSC1; GDSC2; CTRP2 7.7526 9.2084 5.8255 0.4817
ONS-76 GDSC1; CTRP2 7.8476 11.6924 4.7768 4.0678
GMS-10 CTRP2 7.9841 13.8745 3.8251 7.645
CCF-STTG1 CTRP2 8.0311 9.1509 5.9599 0.1165
8-MG-BA GDSC1; CTRP2 8.2188 10.3741 5.5735 0.8818
GOS-3 CTRP2 8.6026 10.5169 5.6868 0.4083
⏷ Show the Full List of 69 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 3.5823 5.1516 2.614 3.7796
TGBC1TKB GDSC1 5.5394 7.0593 2.8286 0.2758
TGBC24TKB GDSC1 5.7362 14.3141 -0.3154 15.2742
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-3 CTRP2 2.3565 5.1189 2.2535 26.7412
KLE GDSC1; CTRP2 3.8607 7.1052 3.3875 18.0796
HEC-151 CTRP2; CTRP1 4.4525 6.6233 4.1922 13.3654
JHUEM-7 CTRP2 4.7433 7.7968 4.054 13.0818
JHUEM-2 CTRP1 5.1668 7.4781 4.6292 20.7691
HEC-265 CTRP2 5.2599 7.5838 4.6785 9.2658
HEC-1-A CTRP2 5.5698 9.7106 3.9662 11.4388
JHUEM-1 CTRP2 5.8076 6.1822 5.7917 3.4776
ESS-1 GDSC1; CTRP2 5.834 6.6264 5.6837 3.7991
HEC-50B CTRP2 5.8769 8.8099 4.69 7.7621
MFE-296 GDSC1; CTRP2 6.0717 6.8671 5.8204 2.6439
MFE-319 GDSC1; CTRP2 6.0815 6.6862 5.9145 2.2389
EFE-184 CTRP2 6.1232 8.5187 5.0538 5.7214
HEC-1-B CTRP2 6.2931 9.0132 4.2094 3.3183
MFE-280 GDSC1 6.6515 8.8848 2.5984 0.3783
HEC-59 CTRP2 7.6294 9.8375 5.4971 1.6106
HEC-251 CTRP2 7.7224 10.2173 5.3805 1.932
HEC-6 CTRP2 8.0078 9.8108 5.7022 0.6586
HEC-108 CTRP2 8.1553 9.3523 5.935 0.1231
RL95-2 GDSC1; CTRP2 8.2606 10.1108 5.6972 0.5343
AN3-CA GDSC1; CTRP2 8.3663 11.1494 5.3238 1.5305
EN GDSC1; CTRP2 8.415 9.6151 5.9375 0.0779
Ishikawa (Heraklio) 02 ER- CTRP2 7.4709 8.5575 5.9555 0.3076
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-195 GDSC1 0.2523 4.1511 -0.2862 40.6535
LB2241-RCC GDSC1; GDSC2 0.5942 2.2988 0.5494 27.5985
KTCTL-13 GDSC1; GDSC2 1.4312 4.4296 0.8775 21.995
UO-31 GDSC1; GDSC2; CTRP2 1.6938 5.9709 1.3624 31.8913
LB996-RCC GDSC1 1.7713 4.7481 1.1038 19.2898
A-498 GDSC1 1.8403 11.2145 -1.9182 32.2573
A-704 GDSC1 2.4363 5.5828 1.3892 15.0547
TK-10 GDSC1 2.4937 5.427 1.5189 14.061
KTCTL-26A GDSC1; GDSC2 3.1514 5.9278 1.8743 9.6685
NCC010 GDSC1; GDSC2 3.1873 5.3539 2.1916 7.5574
769-P GDSC1; CTRP2 3.265 4.613 3.2566 20.3742
KTCTL-140 GDSC1; GDSC2 3.4932 5.5861 2.3293 5.8041
BB65-RCC GDSC1; GDSC2 3.5666 7.3874 1.4893 10.8611
HA7-RCC GDSC1; GDSC2 3.6693 5.1117 2.6974 3.0509
NCC021 GDSC1; GDSC2 3.9188 7.596 1.6597 8.881
CAL-54 GDSC1; CTRP2 3.9479 8.7268 2.8307 19.948
KTCTL-21 GDSC1; GDSC2 4.0229 6.6984 2.1762 5.4499
Caki-2 CTRP2 4.1639 5.9925 4.0479 14.7628
KTCTL-1M GDSC1; GDSC2 4.5518 8.2334 1.8001 6.5707
ACHN GDSC1; CTRP2 4.5528 9.1804 3.2419 16.7799
LB1047-RCC GDSC1; GDSC2 4.8251 11.2575 0.5264 13.199
SN12C GDSC1 4.8818 6.7456 2.6691 1.2559
VMRC-RCW GDSC1; GDSC2; CTRP2 4.9511 7.7471 4.2901 11.6059
SW13 GDSC1 5.4903 6.983 2.8372 0.2746
TUHR10TKB CTRP2 5.7519 8.0374 4.9527 6.9526
KMRC-1 GDSC1; CTRP2 5.7562 10.5481 3.7206 12.0467
SW156 GDSC1; GDSC2 5.7805 7.7226 2.6823 0.5331
TUHR4TKB CTRP2 5.7828 6.8111 5.5536 4.4437
BFTC-909 GDSC1; CTRP2 6.1701 7.4982 5.6029 3.3257
KMRC-2 CTRP2 6.2198 7.0407 5.8743 2.0864
786-O GDSC1; CTRP2 6.3094 10.321 4.3119 8.4615
RXF 393L GDSC1; GDSC2 6.5277 18.1526 -1.6214 18.8839
RCC10RGB GDSC1; CTRP2; CTRP1 6.9207 14.4239 2.7585 15.5101
Caki-1 GDSC1; GDSC2; CTRP2 7.0454 9.4273 5.323 2.9878
VMRC-RCZ GDSC1; CTRP2 7.6571 15.5835 2.7513 12.3522
TUHR14TKB CTRP2 7.9815 12.5343 4.4661 10.512
SNU-1272 CTRP2 8.2941 9.7133 5.8591 0.1983
OS-RC-2 GDSC1; CTRP2 8.367 11.9519 4.9733 2.7271
KMRC-20 GDSC1; CTRP2 8.7819 10.6074 5.7248 0.2791
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 61 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HT115 GDSC1; GDSC2; CTRP2; CTRP1 2.6837 4.5555 2.6602 24.2939
CL-40 CTRP1 2.8526 8.925 1.606 49.7548
GP5d GDSC1 3.4367 4.8708 2.6409 3.9892
SW1116 GDSC1 3.9028 7.2852 1.8011 9.9753
HCC2998 GDSC1 4.3158 8.1484 1.6784 7.8142
DiFi GDSC1 4.347 6.9653 2.2673 5.2477
SW837 GDSC1 4.3704 7.2425 2.1514 4.8563
LS513 GDSC1; CTRP2 4.4068 8.4103 3.4409 16.3729
SW1463 GDSC1 4.4125 8.041 1.7978 6.8814
CL-34 CTRP1 4.4973 9.0861 3.2297 34.0698
SNU-C2B GDSC1 4.5208 7.774 1.9982 5.4608
SW48 GDSC1; CTRP2 4.521 9.0108 3.2879 16.6789
CCK-81 GDSC1; CTRP2 4.7807 7.2928 4.3024 12.015
RKO GDSC1; CTRP2; CTRP1 4.8716 7.4564 4.3313 11.6556
T84 GDSC1; CTRP2 4.8829 6.9184 4.556 10.7609
SNU-C1 GDSC1; CTRP2 4.8859 8.0579 4.0866 12.5805
SNU-C5 GDSC1; CTRP2; CTRP1 4.961 8.526 3.9503 12.9347
MDST8 GDSC1; CTRP2; CTRP1 5.1135 8.8348 3.9567 12.5343
CaR-1 GDSC1 5.1542 7.1167 2.6472 1.0839
GP2d CTRP2 5.2364 9.4663 3.7735 12.9874
KM12 GDSC1; CTRP2; CTRP1 5.2623 6.4633 5.124 7.5419
NCI-H747 GDSC1; CTRP2 5.3411 10.2908 3.4707 13.98
LS123 GDSC1; CTRP2; CTRP1 5.4016 8.9447 4.1821 10.9316
HT-55 GDSC1; CTRP2; CTRP1 5.4601 7.2668 5.0232 7.3811
NCI-H508 GDSC1; GDSC2; CTRP2; CTRP1 5.4617 9.1684 4.1307 11.0042
SW626 GDSC1 5.5357 7.6701 2.6001 0.9502
COLO 320 CTRP2; CTRP1 5.6905 7.2713 5.2552 6.7758
C2BBe1 GDSC1; CTRP2 5.7342 8.2424 4.8367 7.4711
LoVo GDSC1; CTRP2; CTRP1 5.7516 7.8173 5.0584 6.519
SNU-61 GDSC1; CTRP2; CTRP1 5.7584 7.7988 5.0737 6.4401
SW480 CTRP1 5.773 9.112 4.4466 19.0116
SNU-81 GDSC1; GDSC2; CTRP1 5.7731 7.1542 5.3914 5.9251
SNU-175 CTRP1 5.7739 6.978 5.4717 10.2816
CL-11 GDSC1; CTRP2 5.8016 7.3254 5.3404 5.2486
SW948 GDSC1; CTRP2; CTRP1 5.8265 7.6634 5.2039 5.7463
SNU-1040 GDSC1; CTRP1 5.851 6.5268 5.7405 4.8284
SNU-407 GDSC1; CTRP2 5.8605 6.6908 5.6853 3.7212
SNU-283 GDSC2 5.8663 7.739 2.7099 0.4216
LS1034 GDSC1; CTRP2 5.8932 7.6586 5.2697 5.3214
HCT 8 CTRP2; CTRP1 5.9165 6.3633 5.8675 2.871
COLO 320HSR GDSC1 5.9703 7.3486 2.8825 0.0917
COLO 678 GDSC1; CTRP2; CTRP1 6.0953 8.3002 5.1381 5.426
SNU-503 CTRP2 6.194 7.4143 5.6658 3.0123
LS180 GDSC1; CTRP2; CTRP1 6.2086 9.4431 4.6659 7.1756
HCC-56 CTRP2 6.221 7.5008 5.6464 3.0374
CW-2 GDSC1; CTRP2; CTRP1 6.2254 9.4446 4.6795 7.0851
DLD-1 CTRP2 6.2969 7.0533 5.9351 1.6733
SW620 GDSC1; GDSC2; CTRP2; CTRP1 6.3174 7.8251 5.5665 3.1809
RCM-1 [Human ESC] GDSC1; CTRP2; CTRP1 6.6036 11.9051 3.7615 10.1929
SW1417 GDSC1; CTRP2 6.8942 9.1384 5.3574 3.0708
SNU-C4 CTRP2; CTRP1 7.0985 14.3651 2.9277 12.6401
SNU-C2A CTRP2 7.2979 10.5333 4.9637 4.0737
HCT 116 GDSC1; CTRP2; CTRP1 7.5618 12.6224 4.1357 7.0348
SK-CO-1 GDSC1; CTRP2 7.6178 9.8602 5.4804 1.6816
OUMS-23 CTRP2 7.7834 8.8441 5.9758 0.152
LS411N GDSC1; CTRP2 7.893 9.7093 5.6894 0.7664
HT-29 GDSC1; GDSC2; CTRP2; CTRP1 8.0491 9.355 5.8939 0.2106
COLO205 GDSC1; CTRP2 8.1312 10.0441 5.6656 0.6833
COLO201 CTRP2 8.4217 9.7046 5.9093 0.1051
HCT 15 GDSC1; CTRP2 8.5096 10.3289 5.719 0.3791
NCI-H716 GDSC1; CTRP2 8.7031 10.4306 5.7582 0.2472
⏷ Show the Full List of 61 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 4.7262 6.521 2.6856 1.3514
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-182 CTRP2 3.2551 6.1556 3.0189 21.2323
Huh-7 GDSC1 3.6435 5.2691 2.6016 3.7061
Li-7 CTRP2 3.7153 7.7424 2.9939 19.9706
Hep-G2/C3A GDSC1 3.7711 6.5943 2.0433 6.8758
HLE GDSC1 4.0289 6.4661 2.2929 4.7231
SNU-449 GDSC1; CTRP2 4.4508 8.2873 3.5399 15.8698
SNU-398 GDSC1; CTRP2; CTRP1 5.4093 7.9731 4.6513 8.9995
JHH-7 GDSC1 5.5506 7.2049 2.7808 0.3817
JHH-4 GDSC1; CTRP2 5.9496 9.038 4.6424 7.8048
PLC/PRF/5 CTRP2 6.0278 7.6593 5.3947 4.5006
JHH-1 GDSC1; CTRP2 6.0866 8.6123 4.9752 6.1261
SNU-761 CTRP2 6.0915 7.7442 5.4106 4.2957
SNU-878 CTRP2 6.095 7.3053 5.6303 3.3735
SNU-423 GDSC1; CTRP2 6.1934 11.9076 3.4213 12.3747
JHH-2 GDSC1; CTRP2 6.2132 7.1269 5.8256 2.3037
JHH-5 CTRP2 6.5074 9.3495 4.9598 5.3724
Hep-G2 CTRP2; CTRP1 6.6199 7.922 5.7545 1.866
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 6.6445 8.3746 4.706 0.9598
SNU-475 GDSC1; CTRP2 6.6694 11.978 3.778 10.0034
SNU-387 GDSC1; CTRP2 6.7366 14.3563 2.6449 14.3924
JHH-6 GDSC1; CTRP2 7.164 10.3531 4.9577 4.2943
HuH-1 GDSC1; CTRP2 8.2366 9.5936 5.8801 0.1812
HLF CTRP2 8.327 10.3353 5.6388 0.6431
SK-HEP-1 GDSC1; CTRP2 8.3758 9.8189 5.8525 0.1875
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 222 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2722 GDSC1 2.0688 6.2372 0.7226 20.3104
NCI-H64 GDSC1 2.1169 4.0393 0.5832 3.8285
NCI-H2595 GDSC1 2.4392 4.6263 1.841 12.3019
NCI-H3122 GDSC1 2.5429 4.3151 0.7094 2.0837
NCI-H1648 GDSC1 2.8237 5.6745 1.7084 11.7536
NCI-H1341 GDSC1; CTRP2 2.9593 3.6518 2.9593 22.3805
NCI-H2461 GDSC1 3.2015 4.4119 2.6736 4.4688
NCI-H2804 GDSC1; GDSC2 3.2333 6.9549 1.4311 12.1814
NCI-H847 GDSC1 3.3161 5.2271 2.3645 6.0785
NCI-H1963 GDSC1; CTRP1 3.3248 7.6345 2.6179 25.9924
NCI-H2810 GDSC1; GDSC2 3.552 7.0259 1.658 9.8596
NCI-H2731 GDSC1 3.5649 6.246 2.0571 7.326
HCC44 GDSC1; CTRP2 3.6175 4.6984 3.6135 18.0134
NCI-H2591 GDSC1 3.6341 5.4049 2.5278 4.19
NCI-H2869 GDSC1; GDSC2 3.6674 6.004 2.2568 5.8027
EMC-BAC-2 GDSC1 3.6716 7.1403 1.6958 11.5138
EMC-BAC-1 GDSC1; GDSC2 3.7478 5.6879 2.4724 4.2601
LC-2/ad GDSC1; GDSC2 3.8655 5.6499 2.5739 3.3693
NCI-H1304 GDSC1 3.9523 6.4478 2.2481 5.1692
NCI-H1734 GDSC1; GDSC2; CTRP2 4.0417 5.7444 3.964 15.4416
NCI-H2818 GDSC1 4.0496 6.5395 2.2718 4.8063
LC-1/sq GDSC1 4.0742 7.5655 1.7897 7.7015
NCI-H513 GDSC1 4.155 7.2117 2.02 6.107
NCI-H290 GDSC1; GDSC2 4.2089 6.1063 2.5812 2.6516
NCI-H2171 GDSC1; GDSC2 4.2459 5.8355 2.7261 1.7853
NCI-H2369 GDSC1 4.2529 5.9696 2.6699 2.0792
LXF 289 GDSC1; CTRP2 4.274 7.664 3.6175 16.0435
NCI-H1975 GDSC1 4.3127 10.6448 0.4498 14.86
NCI-H1436 GDSC1; GDSC2 4.3706 6.3004 2.5892 2.3325
NCI-H1993 GDSC1 4.4373 6.3228 2.6175 2.0757
NCI-H1184 CTRP2 4.4377 6.1543 4.3089 12.9872
DV-90 CTRP2 4.5347 7.1339 4.1021 13.4656
A-427 GDSC1; GDSC2 4.5968 13.0326 -0.5162 18.8274
NCI-H1437 GDSC1; GDSC2 4.6065 6.5116 2.6276 1.7816
NCI-H1435 GDSC1; CTRP2 4.6302 9.2582 3.2829 16.4234
NCI-H1838 GDSC1; CTRP2 4.6309 7.5766 4.0291 13.4801
CAL-12T GDSC1; GDSC2; CTRP2; CTRP1 4.6871 8.6156 3.6346 14.8849
IST-SL2 GDSC1; GDSC2 4.6996 8.1792 1.923 5.5484
HCC1588 CTRP2 4.7145 9.6597 3.178 16.6297
RERF-LC-KJ GDSC1 4.7706 8.3267 1.8993 5.5493
EBC-1 GDSC1; CTRP2 4.8196 6.2059 4.7125 10.3706
HCC33 GDSC1; GDSC2 4.8402 6.839 2.6095 1.5759
NCI-H1048 GDSC1 4.843 6.7113 2.6643 1.3186
NCI-H82 GDSC1 4.8502 6.9029 2.5876 1.668
NCI-H661 GDSC1; CTRP2 4.8645 6.5896 4.651 10.4587
HCC1833 CTRP2; CTRP1 4.8725 7.8111 4.1813 12.2406
PC-14 GDSC1; GDSC2; CTRP2 4.8893 7.2508 4.4341 11.2093
NCI-H1573 GDSC1 4.8975 7.2457 2.4654 2.2104
NCI-H2135 GDSC1; GDSC2 4.9182 6.7973 2.6654 1.2342
NCI-H1373 CTRP2 4.9425 6.6993 4.6988 10.0536
EPLC-272H GDSC1; CTRP2 4.9491 7.0238 4.587 10.4572
NCI-H345 GDSC1; GDSC2 4.9542 5.9694 2.9949 0.1336
IST-SL1 GDSC1; GDSC2 4.9547 6.6391 2.7463 0.8639
NCI-H810 GDSC1; CTRP2 4.9677 6.8662 4.6664 10.1033
NCI-H1666 GDSC1; CTRP2 4.9812 6.6553 4.7558 9.7288
COLO 668 GDSC1; CTRP2 4.9882 6.9174 4.6693 10.0339
Lu-134-A GDSC1; GDSC2 5.0281 9.9167 1.3151 8.3997
NCI-H596 GDSC1; CTRP1 5.0401 6.4463 4.8872 10.5113
DMS 79 GDSC1; GDSC2 5.059 6.8225 2.7208 0.8756
SCLC-21H CTRP1 5.0931 6.5269 4.9198 18.8727
CPC-N GDSC1 5.0954 6.9588 2.6833 0.9912
NCI-H1770 GDSC1; GDSC2 5.1277 8.8011 1.901 4.8894
NCI-H647 GDSC1; GDSC2; CTRP2 5.1691 8.7764 4.0385 12.0684
SBC-3 GDSC1 5.1913 8.3431 2.1449 3.4555
NCI-H358 GDSC1; CTRP2 5.1989 7.3933 4.699 9.3443
NCI-H2444 GDSC1; GDSC2; CTRP2 5.2196 7.2576 4.7783 8.9786
NCI-H146 GDSC1; GDSC2 5.2352 6.9459 2.7496 0.642
NCI-H3255 GDSC1; GDSC2; CTRP1 5.2369 8.5114 4.2297 12.8928
MOR/CPR CTRP2 5.2377 6.1461 5.1816 7.4095
NCI-H720 GDSC1 5.2425 6.3475 2.9679 0.1096
NCI-H2122 GDSC1; CTRP2; CTRP1 5.2448 7.2553 4.8055 8.8049
NCI-H1693 GDSC1; CTRP2 5.2518 7.7061 4.6157 9.5367
Lu-135 GDSC1 5.2527 7.6694 2.4684 1.7593
NCI-H187 GDSC1 5.2533 6.6985 2.8488 0.3412
NCI-H1915 GDSC1; CTRP2 5.2656 9.1444 3.9564 12.1733
NCI-H2066 GDSC1 5.2716 7.0352 2.731 0.8472
LCLC-97TM1 GDSC1; CTRP2 5.2847 7.5149 4.7343 8.9807
NCI-H2087 GDSC1; CTRP2 5.2894 6.6532 5.09 7.5889
Lu-165 GDSC1 5.2898 6.5925 2.9004 0.2114
Lu-99A GDSC1 5.3062 7.2911 2.6469 0.9555
HCC2108 CTRP2; CTRP1 5.3148 8.9041 4.1187 11.3946
NCI-H2803 GDSC1; GDSC2 5.3232 7.0496 2.7471 0.5944
PaCa-3 GDSC1 5.3807 7.4834 2.6045 1.0566
NCI-H2347 GDSC1 5.4269 7.7691 2.5115 1.3902
NCI-H1581 GDSC1; CTRP2 5.4301 6.3357 5.3449 6.234
NCI-H524 GDSC1 5.4404 7.298 2.7021 0.6656
SHP-77 GDSC1; CTRP2 5.4475 9.1152 4.1432 10.9851
COR-L88 GDSC1 5.4588 7.1518 2.7641 0.4684
NCI-H2227 GDSC1; GDSC2 5.5018 7.3353 2.7135 0.5927
NCI-H1092 GDSC1 5.5079 7.0696 2.813 0.3219
NCI-H2373 GDSC1 5.5203 7.5546 2.6381 0.8266
COR-L279 GDSC1 5.5276 7.0081 2.8422 0.3131
LB647-SCLC GDSC1; GDSC2 5.5307 7.3439 2.722 0.551
Lu-99 CTRP2 5.5359 6.3722 5.4499 5.5342
NCI-H510A GDSC1; GDSC2 5.5535 7.1357 2.8068 0.3186
NCI-H1688 GDSC1 5.5578 7.5142 2.6693 0.6974
COR-L32 GDSC1; GDSC2 5.5589 7.9784 2.4887 1.3615
NCI-H209 GDSC1 5.5619 7.5375 2.6622 0.7177
Ms-1 GDSC1 5.5631 7.2539 2.7679 0.4086
LK-2 GDSC1 5.5647 7.4396 2.7002 0.5969
DMS 454 CTRP2 5.5649 7.7002 4.9321 7.4816
COR-L321 GDSC1; GDSC2 5.5758 7.1295 2.8173 0.287
NCI-H2170 GDSC1; CTRP2 5.6313 7.6074 5.0409 6.8784
COR-L303 GDSC2 5.6325 7.0204 2.876 0.1614
NCI-H748 GDSC1; GDSC2 5.6333 7.6819 2.6374 0.7532
UMC-11 GDSC1 5.6619 7.581 2.6871 0.5817
Lu-139 GDSC1 5.6673 7.221 2.8191 0.2528
NCI-H2029 GDSC1; GDSC2; CTRP2 5.6815 6.4067 5.5981 4.5577
HCC366 GDSC1; GDSC2; CTRP2 5.7038 9.3 4.2909 9.7992
HCC827 GDSC1; CTRP1 5.707 6.9393 5.42 5.9897
NCI-H322M GDSC1 5.7193 8.1059 2.5109 1.1374
SBC-1 GDSC1; GDSC2 5.7356 7.5289 2.7353 0.4148
SK-MES-1 GDSC1; CTRP2 5.7596 6.5938 5.6173 4.2607
HCC2935 CTRP2; CTRP1 5.7697 8.0026 4.9864 6.7727
DMS 53 GDSC1; CTRP2 5.7792 6.5407 5.6582 4.0498
NCI-H446 GDSC1; CTRP2 5.8032 6.5888 5.6658 3.9534
LUDLU-1 CTRP2 5.8035 6.7079 5.6185 4.135
DMS 273 GDSC1; CTRP2 5.8036 6.6434 5.6448 4.0328
NCI-H1694 GDSC1; CTRP2; CTRP1 5.81 6.4607 5.72 3.7297
NCI-H522 GDSC1; CTRP2 5.8168 6.6398 5.6601 3.9375
NCI-H2141 GDSC1; CTRP1 5.8238 7.2392 5.4026 5.7267
NCI-H1563 GDSC1; CTRP2 5.8562 7.722 5.204 5.6773
NCI-H211 GDSC1; CTRP2 5.858 7.3575 5.3803 4.9501
ChaGo-K-1 GDSC1; GDSC2; CTRP2 5.8619 6.554 5.7417 3.4998
NCI-H1836 GDSC1; GDSC2; CTRP1 5.8659 7.1061 5.5062 5.1216
NCI-H1155 GDSC1; CTRP2 5.8764 6.6804 5.7062 3.5969
NCI-H2795 GDSC1 5.9047 8.0923 2.5953 0.7197
NCI-H1339 CTRP2 5.9104 6.5232 5.8054 3.1212
NCI-H1755 GDSC1; CTRP2; CTRP1 5.9154 8.4439 4.9056 6.7807
COR-L105 GDSC1; CTRP2 5.9169 8.5318 4.8636 6.9525
NCI-H1105 GDSC1; GDSC2; CTRP2; CTRP1 5.9204 6.6131 5.7803 3.19
NCI-H740 GDSC2 5.9236 8.024 2.6284 0.611
NCI-H1355 GDSC1; CTRP2 5.9305 7.2311 5.5107 4.2449
NCI-H1792 GDSC1; CTRP2 5.9405 7.4827 5.3995 4.6779
NCI-H2073 CTRP1 5.9434 6.5025 5.8485 6.148
HCC1438 CTRP2 5.9542 6.7229 5.7688 3.1454
NCI-H322 CTRP2 5.9586 7.2955 5.5069 4.1941
NCI-H1781 GDSC1; CTRP1 5.971 6.5837 5.8456 3.2442
HCC1359 CTRP1 5.9828 6.468 5.9037 5.4603
DMS 114 GDSC1; CTRP2 5.9899 6.5634 5.8738 2.6389
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2 6.0033 7.1047 5.6412 3.5387
HCC1195 CTRP2; CTRP1 6.0131 7.843 5.2908 4.9647
NCI-H1650 GDSC1; CTRP2 6.0177 8.6695 4.8858 6.6441
T3M-10 CTRP2; CTRP1 6.0179 7.12 5.6479 3.4768
NCI-H2081 GDSC1; GDSC2; CTRP2; CTRP1 6.0225 6.8478 5.7811 2.9231
COR-L95 GDSC1; CTRP2 6.0264 6.8006 5.8068 2.8096
NCI-H1651 GDSC1 6.0405 7.93 2.7078 0.3581
NCI-H1944 GDSC1; CTRP2 6.0524 7.3638 5.5622 3.7511
NCI-H2405 GDSC1; CTRP2 6.069 8.1477 4.4726 2.5251
NCI-H841 GDSC1; CTRP2; CTRP1 6.0845 6.7966 5.8662 2.427
NCI-H2196 GDSC1; GDSC2; CTRP2 6.0878 6.9886 5.7779 2.7801
LK2 CTRP2 6.1029 6.6017 5.9743 1.9457
Sq-1 CTRP2; CTRP1 6.1311 7.6753 5.4803 3.9205
NCI-H2228 GDSC1; CTRP2 6.1342 7.2631 5.687 3.0517
NCI-H226 GDSC1; CTRP2 6.1351 7.6607 5.4911 3.8666
HCC78 GDSC1; CTRP2 6.1384 9.9627 4.3465 8.6541
HCC4006 CTRP2; CTRP1 6.1389 7.1097 5.7667 2.7102
COR-L23 GDSC1; CTRP1 6.1422 6.8479 5.8974 2.506
HCC15 GDSC1; CTRP2; CTRP1 6.1428 7.4191 5.6177 3.3218
NCI-H2106 CTRP2 6.1647 7.4532 5.6205 3.2636
Lu-65 GDSC1; CTRP2 6.1647 7.2018 5.745 2.7441
EKVX GDSC1; GDSC2; CTRP2 6.1695 7.8385 5.4332 4.0366
NCI-H2110 GDSC1; GDSC2; CTRP2; CTRP1 6.1883 7.6091 5.5638 3.451
NCI-H250 GDSC2 6.1965 7.8001 2.809 0.1413
COR-L51 CTRP1 6.2318 11.449 3.6829 22.3628
KNS-62 GDSC1; CTRP2 6.2402 7.2766 5.7749 2.4599
LOU-NH91 GDSC1; CTRP2 6.248 8.7368 5.0524 5.4753
Calu-6 GDSC1; CTRP2 6.2676 7.8102 5.532 3.4234
Calu-3 GDSC1; CTRP2 6.2858 8.7177 5.0938 5.2273
NCI-H1876 GDSC1; CTRP1 6.2893 7.345 5.7829 2.6969
SW1271 GDSC1; CTRP2 6.3281 7.5926 5.6917 2.6347
ABC-1 GDSC1; GDSC2 6.3345 8.2975 2.6875 0.3025
NCI-H2023 GDSC1; CTRP2; CTRP1 6.3611 7.4075 5.8114 2.0696
NCI-H460 GDSC1; GDSC2; CTRP2; CTRP1 6.3682 7.131 5.9553 1.4527
HOP-62 GDSC1; CTRP2 6.3751 7.6556 5.6989 2.5158
SK-LU-1 GDSC1; CTRP2; CTRP1 6.404 7.7816 5.6593 2.6281
NCI-H835 GDSC1 6.4324 8.3254 2.7132 0.2873
COLO 699 CTRP2; CTRP1 6.444 8.1708 5.4971 3.2354
RERF-LC-A1 CTRP2 6.4466 8.5933 5.2884 4.1058
NCI-H2342 GDSC1; CTRP2; CTRP1 6.4677 10.3142 4.4459 7.5993
NCI-H2126 CTRP2 6.4928 7.7681 5.7358 2.1507
NCI-H1793 GDSC1; CTRP2 6.52 7.793 5.7443 2.0696
NCI-H520 GDSC1; CTRP2 6.5323 7.7404 5.7795 1.903
A-549 GDSC1; CTRP2 6.6901 8.291 5.6248 2.2891
HCC2279 CTRP2 6.8027 12.8384 3.4552 11.0784
NCI-H2085 GDSC1; CTRP2 6.8074 11.4704 4.1403 8.2577
RERF-LC-Ad1 CTRP2 6.8105 12.154 3.8024 9.6475
NCI-H441 GDSC1; CTRP2; CTRP1 6.923 10.2177 4.8494 5.1164
NCI-H2030 GDSC1; GDSC2; CTRP2; CTRP1 6.9943 9.8544 5.0799 4.0534
NCI-H1869 GDSC1; CTRP2 7.0434 12.1478 3.9863 8.4843
RERF-LC-Sq1 GDSC1 7.1128 9.3848 2.5921 0.262
NCI-H2172 GDSC1; GDSC2; CTRP2; CTRP1 7.2172 8.7767 5.7359 1.1783
NCI-H2009 GDSC1; CTRP2 7.2414 10.3287 5.0234 3.9142
HOP-92 GDSC1; CTRP2 7.2988 15.1959 2.6705 13.2731
NCI-H2291 GDSC1; GDSC2; CTRP2 7.6436 10.9154 5.0111 3.4167
NCI-H1395 CTRP2 7.6551 10.2021 5.3481 2.1223
LCLC-103H GDSC1; CTRP2 7.7027 8.9415 5.9073 0.3109
BEN GDSC1; GDSC2; CTRP2 7.7882 8.7819 5.9997 0.1154
NCI-H727 GDSC1; CTRP2 7.8929 13.2332 4.0718 6.7976
LC-1/sq-SF CTRP2 7.9657 9.1867 5.9225 0.1872
IA-LM GDSC1; CTRP2 8.1076 9.7095 5.7858 0.4019
NCI-H196 GDSC1; CTRP2 8.1105 9.6226 5.8198 0.3284
RERF-LC-Ad2 CTRP2 8.1252 11.745 4.9251 3.1652
NCI-H526 GDSC1; CTRP2 8.1492 9.8916 5.7337 0.5022
SBC-5 GDSC1; CTRP2 8.1571 9.1733 5.997 0.0577
NCI-H2286 CTRP2 8.2011 9.7924 5.7934 0.3471
NCI-H650 GDSC1; CTRP2 8.2012 18.9035 1.5204 15.8235
RERF-LC-MS GDSC1; GDSC2; CTRP2 8.2866 10.295 5.6366 0.6707
VMRC-LCD GDSC1; CTRP2 8.3205 9.8515 5.8194 0.2562
HCC95 CTRP2 8.3629 10.2047 5.705 0.4685
NCI-H23 GDSC1; CTRP2 8.4201 11.6016 5.1576 2.0324
HCC1171 CTRP2 8.4499 14.9738 3.6152 7.7976
NCI-H69 GDSC1; CTRP2 8.4647 10.8678 5.4893 0.96
NCI-H838 GDSC1; GDSC2; CTRP2 8.4855 9.7148 5.9283 0.0771
NCI-H292 GDSC1; GDSC2; CTRP2 8.5894 10.1208 5.8255 0.1759
NCI-H1568 GDSC1; CTRP2 8.605 10.7848 5.5858 0.6301
NCI-H1299 GDSC1; CTRP2 8.6259 10.7596 5.6046 0.5761
NCI-H1703 GDSC1; CTRP2 8.9088 10.6449 5.7594 0.1954
NCI-H1623 GDSC1; CTRP2 9.2087 10.8429 5.7988 0.1011
Calu-1 CTRP2 10.1336 19.357 2.6411 9.1541
SW1573 GDSC1; CTRP2 10.1949 24.6197 0.1653 16.8823
Hs 888.Lu CTRP2 6.969 10.1708 4.9065 4.8064
⏷ Show the Full List of 222 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 3.8686 6.0021 2.4055 4.3921
Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 5.7299 6.6762 5.5535 4.587
OVCAR-3 GDSC1 3.0691 4.6607 2.4317 6.4172
COV362 CTRP2; CTRP1 3.3914 7.4122 2.7715 21.7253
SNU-8 CTRP2 3.5115 5.185 3.4743 18.8308
JHOC-5 CTRP2; CTRP1 3.9115 7.3761 3.3435 18.0991
Caov-4 GDSC1 4.0966 8.2299 1.4798 9.5322
JHOS-4 GDSC2 4.4684 6.5377 2.5391 2.4505
TYK-nu GDSC1; CTRP2; CTRP1 4.7987 7.7179 4.1451 12.5776
COV434 CTRP2; CTRP1 4.9776 6.5868 4.7748 9.6687
A2780 GDSC1; CTRP2; CTRP1 5.0442 6.4859 4.8795 9.0864
OVTOKO GDSC1; CTRP2 5.0814 13.7036 1.5524 21.7893
SNU-119 CTRP2 5.0952 7.5479 4.5252 10.3012
Caov-3 GDSC1; GDSC2; CTRP2; CTRP1 5.1676 7.0435 4.8116 8.9904
OVKATE GDSC1; CTRP1 5.2063 7.1442 4.8115 10.2959
OVCAR-4 GDSC1; CTRP2; CTRP1 5.3444 7.2178 4.9249 8.0722
ES-2 GDSC1 5.5279 7.183 2.7799 0.3938
RMG-I GDSC1; CTRP2; CTRP1 5.5901 8.773 4.4435 9.422
IGROV-1 GDSC1; CTRP2; CTRP1 5.6836 7.1138 5.3193 5.6283
OVK18 GDSC1; GDSC2; CTRP1 5.8221 6.3047 5.781 4.0212
OVCAR-8 GDSC1; CTRP2; CTRP1 5.8363 7.4386 5.3208 5.2445
OAW42 GDSC1; CTRP2; CTRP1 5.8458 7.5905 5.2574 5.4819
MCAS CTRP2 5.8645 7.1589 5.4803 4.5281
SNU-840 CTRP2; CTRP1 5.9289 7.3738 5.4409 4.5346
EFO-21 GDSC1; CTRP2 5.9712 7.5149 5.4128 4.5527
TOV-112D GDSC1; CTRP2 6.0518 6.8403 5.8136 2.7197
OC 314 GDSC1; CTRP2 6.1024 6.9493 5.8107 2.6114
HEY A8 CTRP2 6.195 7.783 5.4831 3.7751
OVSAHO CTRP2 6.2683 9.1126 4.1455 3.6271
RMUG-S CTRP1 6.3285 7.3459 5.8155 4.5376
OVCAR-5 GDSC1; CTRP2 6.3697 7.712 5.6663 2.6624
FU-OV-1 GDSC1; CTRP2 6.4329 16.7325 1.2088 20.0469
COV644 CTRP2; CTRP1 6.4743 7.8281 5.6917 2.3669
EFO-27 GDSC1; GDSC2; CTRP2; CTRP1 6.4805 7.8208 5.7002 2.3206
OV-90 GDSC1; CTRP2; CTRP1 6.5312 7.4924 5.9006 1.4042
JHOM-1 CTRP2; CTRP1 6.9145 10.8413 4.535 6.4339
OV7 CTRP2; CTRP1 7.1195 18.4264 0.9208 19.642
ONCO-DG-1 CTRP2 7.2374 9.6716 5.3348 2.6766
Kuramochi GDSC1; CTRP2 7.3228 13.4681 3.5448 9.8081
OAW28 GDSC1; CTRP2 7.4275 9.4572 5.5517 1.6232
SK-OV-3 GDSC1; CTRP2 7.5236 14.6354 3.1192 11.1597
ES2 CTRP2 7.6585 9.5211 5.651 1.0597
OV56 GDSC1; CTRP2 7.946 11.3769 4.9856 3.1448
TOV-21G GDSC1; CTRP2 8.0866 9.8179 5.7349 0.5308
DOV13 GDSC1; CTRP2 8.2435 9.6885 5.8486 0.2296
JHOS-2 GDSC1; GDSC2; CTRP2 8.414 10.2138 5.7229 0.4083
OVISE GDSC1; CTRP2 8.4302 9.8917 5.847 0.1823
⏷ Show the Full List of 46 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 5.7853 6.4193 5.7071 3.8493
H-STS CTRP2 6.9883 9.4198 5.287 3.2168
P-STS CTRP2 8.4047 9.73 5.8943 0.1251
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 6.0571 6.6815 5.892 2.3909
Yamato-SS CTRP2 6.0674 6.6351 5.9233 2.2396
SW872 GDSC1 2.3124 3.8306 2.049 11.5768
VA-ES-BJ GDSC1 2.5333 3.3447 2.4549 8.3273
Hs 633.T GDSC1 2.5697 5.2696 1.6672 12.8826
SW982 GDSC1; CTRP2 2.8539 8.295 1.8615 26.5591
GCT GDSC1; CTRP2 3.5017 9.38 2.0868 23.9095
RD GDSC1; CTRP2 3.8341 5.3717 3.7952 16.6894
EW-8 GDSC1 4.1873 5.8229 2.6978 2.0326
Rh41 GDSC1; CTRP2 4.188 6.2876 4.0024 14.8502
STS-0421 GDSC1; GDSC2 4.2687 6.43 2.4682 3.1929
TE 441.T GDSC1; GDSC2 4.9613 6.1495 2.9342 0.2557
A-204 GDSC1; CTRP2 5.0144 8.5054 4.0129 12.55
Rh18 GDSC1; CTRP2 5.0148 7.0961 4.6287 10.1147
G-402 GDSC1; CTRP2 5.0351 6.9251 4.7167 9.722
Hs 729.T CTRP2 5.1274 7.9704 4.3709 10.8307
SW684 GDSC1 5.315 12.9259 0.0625 14.4279
SK-LMS-1 GDSC1; CTRP2 5.3179 11.3026 2.9523 16.108
HT-1080 GDSC1; CTRP2; CTRP1 5.502 8.1596 4.6544 8.762
MFH-ino GDSC1 5.6105 7.636 2.6452 0.7421
TTC-709 CTRP2 5.634 7.3664 5.1551 6.4107
RKN GDSC1; CTRP2; CTRP1 5.728 9.1499 4.3869 9.3473
Rh30 GDSC1 5.8212 7.5539 2.7589 0.3257
BT-12 CTRP2 5.9228 6.2516 5.9034 2.7231
TE 617.T CTRP2 5.9347 6.5441 5.8231 2.9856
Tm87-16 CTRP2 6.0217 6.6491 5.8704 2.5679
BT-16 CTRP2 6.091 6.948 5.8004 2.6801
KYM-1 GDSC1; CTRP2 6.4353 7.5189 5.8151 1.9197
G-401 GDSC1; CTRP2 7.0724 9.1668 5.4658 2.3794
MES-SA GDSC1; CTRP2 7.4668 9.0074 5.7706 0.8329
SK-UT-1 GDSC1; CTRP2 9.4265 15.8194 3.8434 5.6878
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 8.1251 10.1959 5.6015 0.8636
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; CTRP2 4.4777 7.177 4.0248 13.9197
NCI-H28 GDSC1; CTRP2 5.5813 12.8745 2.4097 17.6182
NCI-H2452 GDSC1; CTRP2 5.9307 11.0945 3.6022 12.1677
MPP 89 GDSC1; CTRP2 6.0946 8.8059 4.8858 6.4839
ACC-MESO-1 CTRP2 8.2993 11.8993 4.9579 2.8534
JL-1 CTRP2 8.357 9.7516 5.8692 0.1677
NCI-H2052 GDSC1; CTRP2 8.9554 10.9742 5.6593 0.3385
IST-Mes1 GDSC1; CTRP2 11.2311 25.4054 0.4961 14.5494
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1; CTRP2 3.1899 4.2466 3.1885 20.8506
PC-3 GDSC1 4.0064 5.9891 2.5066 3.4783
22Rv1 GDSC1; CTRP2 5.0295 7.6801 4.4 10.967
NCI-H660 GDSC2; CTRP2 5.4999 6.6504 5.3177 6.13
LNCaP clone FGC GDSC1; CTRP2 5.7935 6.64 5.6354 4.0967
PaCa-3 CTRP2 6.3721 9.889 4.58 7.2176
DU145 GDSC1; CTRP2 6.8236 9.0608 5.3448 3.2312
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 5.3614 7.1701 2.7175 0.6657
YD-15 CTRP2 8.3658 9.6992 5.8909 0.1368
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 4.7883 6.6357 2.6686 1.3595
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MKN28 GDSC1 2.3437 7.2818 -0.8294 13.4625
GCIY GDSC1 3.6437 5.6487 0.6872 0.8938
OCUM-1 GDSC1 4.0245 6.1138 0.6687 0.6973
SNU-16 GDSC1; CTRP2 4.0755 5.9364 3.9638 15.3356
SNU-5 GDSC1; CTRP2 4.2374 6.1748 4.0854 14.4017
HSC-39 GDSC1 4.4138 5.9761 2.7564 1.3913
SNU-620 CTRP2 4.6017 7.8827 3.8703 14.1773
NUGC-4 GDSC1; CTRP2 4.8338 8.9027 3.6496 14.4565
TMK-1 GDSC1; GDSC2 4.9385 12.2466 0.1246 14.9887
23132/87 GDSC1; CTRP2 4.9704 7.275 4.5098 10.6951
TGBC11TKB GDSC1 4.9873 7.2664 2.5037 1.9045
GSS CTRP2 5.0477 7.2568 4.5986 10.141
HuG1-N CTRP2 5.1709 7.2187 4.7437 9.2442
SNU-719 CTRP2 5.2372 8.6699 4.1552 11.4305
ECC10 GDSC1; CTRP2 5.2407 6.1698 5.1797 7.4068
SNU-668 CTRP2 5.3423 6.6455 5.1497 7.2128
SK-GT-2 GDSC1 5.4318 8.6387 2.1477 3.8417
SCH GDSC1; GDSC2 5.4713 7.0338 2.8119 0.3392
HGC-27 GDSC1; CTRP2 5.5701 6.4207 5.4725 5.3493
SNU-1 GDSC1; CTRP2 5.5999 7.4638 5.0763 6.8128
Hs 746.T GDSC1; CTRP2 5.8071 6.9798 5.5047 4.5737
SNU-601 CTRP2 5.815 8.0725 4.9951 14.1872
SNU-216 CTRP2 5.8429 13.2914 2.4304 16.9827
MKN74 CTRP2 5.9877 7.3609 5.5031 4.1425
SH-10-TC CTRP2 5.9878 7.9027 5.2383 5.2386
IM95 GDSC1; CTRP2 6.0271 10.5506 3.9571 10.5034
MKN7 GDSC1; GDSC2; CTRP2 6.0532 8.9357 4.7849 6.992
NUGC-3 GDSC1; CTRP2 6.1031 7.7509 5.4178 4.2411
RF-48 GDSC1 6.1285 7.8043 2.7837 0.1907
NCI-N87 GDSC1; CTRP2 6.1591 10.0487 4.3212 8.7183
KATO III GDSC1; CTRP2 6.4471 10.0123 4.5799 7.0765
AGS GDSC1; CTRP2; CTRP1 6.4619 7.6027 5.7941 1.9607
LMSU CTRP2 6.7747 8.9217 5.3774 3.1742
GSU CTRP2 7.0235 7.5549 6.1477 0.0861
RERF-GC-1B GDSC1 7.0629 9.2071 2.635 0.2096
MKN1 GDSC1; CTRP2 7.1658 9.8931 5.1813 3.3865
MKN45 GDSC1; CTRP2 7.5058 9.5325 5.5629 1.5014
KE-39 CTRP2 7.5352 10.3499 5.2069 2.7945
ECC12 GDSC1; GDSC2; CTRP2 7.8557 10.0478 5.5285 1.293
Fu97 GDSC1; CTRP2 8.9103 10.5661 5.7875 0.1591
SNG-M GDSC1; CTRP2 4.3148 9.1544 3.0152 18.2732
SNU-1077 CTRP2 4.8603 7.7618 4.1901 12.2383
SNU-685 CTRP2 6.5003 9.9921 4.6333 6.7536
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
B-CPAP GDSC1; CTRP2 2.916 4.6939 2.8923 22.7483
K5 GDSC1 3.0014 6.6493 1.3841 13.1835
WRO GDSC1 3.3899 7.3292 1.3746 12.0653
KMH-2 GDSC1; GDSC2 3.7339 6.0699 2.2743 5.5264
ASH-3 GDSC1 3.9176 8.6355 1.1438 11.9954
IHH-4 GDSC1 4.0888 5.8792 2.6119 2.6936
CGTH-W-1 GDSC1; CTRP2 4.2767 7.7694 3.5776 16.1897
SW579 CTRP2 4.2873 6.1849 4.1374 14.0624
HTC-C3 GDSC1 4.5141 7.0053 2.3535 3.4087
FTC-238 CTRP2 4.5896 8.8376 3.4356 15.9216
TT GDSC1; CTRP2 4.7473 5.8427 4.7066 10.6185
8305C GDSC1; CTRP2 5.3549 8.8295 4.1929 10.9967
TT2609-C02 GDSC1; CTRP2 6.0318 8.0964 5.1827 5.3745
ML-1 [Human leukemia] GDSC1; GDSC2; CTRP2 6.0684 8.751 4.8902 6.5198
CAL-62 GDSC1; CTRP2 6.3925 7.6664 5.7075 2.4471
FTC-133 GDSC1; CTRP2 6.4549 8.08 5.5511 2.9894
BHT-101 GDSC1; CTRP2 8.3139 9.9211 5.7913 0.3096
8505C GDSC1; CTRP2 8.9467 19.0762 1.9778 13.1003
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H3118 GDSC1 2.6097 5.5075 1.5907 13.2116
BB49-HNC GDSC1 3.3559 5.4286 2.2967 6.3922
PCI-38 GDSC1 3.5223 12.066 -0.8843 23.2959
HO-1-N-1 GDSC1 3.737 5.6602 2.4781 4.2499
HO-1-u-1 GDSC1 3.7824 5.7142 2.4845 4.1038
SAT [Human HNSCC] GDSC1 3.8266 8.5313 -0.4416 7.1374
PCI-15A GDSC1; GDSC2 3.8562 5.6474 2.5687 3.4212
BICR 78 GDSC1 3.9358 5.9683 2.4688 3.8557
SKN-3 GDSC1 4.0702 7.0685 2.0297 6.2397
YD-10B CTRP2 4.2751 7.9391 3.5059 16.4709
PCI-30 GDSC1 4.4522 8.1883 1.7541 7.0563
PCI-06A GDSC1; GDSC2 4.5199 6.7839 2.4581 2.8126
SCC-25 GDSC1; GDSC2; CTRP2 4.5837 5.9 4.5213 11.7822
BB30-HNC GDSC1; GDSC2 4.676 7.033 2.4364 2.682
KOSC-2 GDSC1; GDSC2 4.7061 7.1431 2.4044 2.8085
DOK GDSC1 4.9514 7.4133 2.4215 2.3597
PCI-04B GDSC1; GDSC2 5.037 6.9268 2.6691 1.1015
JHU-011 GDSC1; GDSC2 5.0776 7.4852 2.4572 2.0177
Ca9-22 GDSC1 5.1083 11.8548 0.437 13.0159
BICR 10 GDSC1 5.1238 14.4008 -0.797 18.7509
JHU-022 GDSC1 5.1543 7.2324 2.6006 1.2774
KON GDSC1; GDSC2 5.1766 6.6104 2.8509 0.371
Detroit 562 GDSC1; CTRP2 5.1883 6.3799 4.6779 3.1859
OSC-19 GDSC1; GDSC2 5.2896 7.0741 2.7237 0.6925
LB771-HNC GDSC1 5.3602 7.5718 2.5599 1.2521
SNU-899 CTRP2 5.4314 6.5972 5.2631 6.5314
JHU-029 GDSC1; GDSC2 5.4463 7.6077 2.5849 1.0777
HSC-4 GDSC1; CTRP2 5.5565 7.9932 4.7862 8.0947
PE/CA-PJ34 (clone C12) CTRP2 5.5934 6.4768 5.4798 5.2535
HSC-2 GDSC1; CTRP2 5.6189 6.601 5.4638 5.2401
BICR 56 CTRP2 5.6326 10.9957 3.3883 13.6704
SAS GDSC1 5.6624 7.6301 2.669 0.6355
SCC-15 GDSC1 5.6985 7.5236 2.7227 0.4637
PE/CA-PJ49 CTRP2 5.7203 6.3555 5.6559 4.2306
BHY GDSC1; GDSC2; CTRP2 5.7216 7.7724 5.051 6.6197
CAL-33 GDSC1; CTRP2 5.9675 7.2457 5.5393 4.0403
BICR 18 CTRP2 6.008 9.8616 4.2842 9.1796
FaDu GDSC1; CTRP2 6.0416 6.8148 5.8154 2.7373
SCC-4 GDSC1; CTRP2 6.0714 8.2532 5.1403 5.4672
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 6.1036 7.0037 5.7855 2.712
PE/CA-PJ41 (clone D2) CTRP2 6.1109 7.6243 5.4875 3.9336
YD-8 CTRP2 6.153 10.083 4.2989 8.8238
SCC-9 GDSC1; CTRP2; CTRP1 6.1902 6.9484 5.8931 2.0721
OSC-20 GDSC1 6.2335 8.0137 2.7492 0.2206
BICR 16 CTRP2 6.266 7.1739 5.8485 2.0988
BICR 6 CTRP2 6.2717 6.8657 6.0071 1.4219
UPCI-SCC-090 GDSC1 6.4007 8.4036 2.6746 0.3071
HSC-3 GDSC1; CTRP2 6.5798 8.0502 4.8088 0.6779
BICR 22 GDSC1; CTRP2 6.9629 8.5833 5.6704 1.7187
BICR 31 GDSC1; GDSC2; CTRP2 7.5187 9.4488 5.6073 1.3327
SNU-46 CTRP2 8.0578 11.9139 4.8062 3.6926
SNU-1076 CTRP2 8.1246 9.7814 5.7655 0.4397
SNU-1214 CTRP2 8.5449 10.9659 5.4873 0.9156
SNU-1066 CTRP2 8.6288 10.3177 5.7702 0.2483
CAL-27 GDSC1; CTRP2 8.6541 9.9546 5.906 0.0758
SNU-1041 CTRP2 9.1341 10.9938 5.7201 0.1996
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
5637 GDSC1; CTRP2 3.538 6.342 3.2782 19.4372
U-BLC1 CTRP2 3.8372 6.2961 3.6173 17.305
SW1710 GDSC1; CTRP2 4.1879 8.2095 3.3012 17.4974
BFTC-905 GDSC1 4.2146 21.0139 -4.7916 32.2238
RT-4 GDSC1; CTRP2 4.5773 6.2547 4.4359 12.1038
JMSU-1 CTRP2 5.2076 6.5823 5.0259 8.0651
RT-112 GDSC1; CTRP2 5.3193 6.263 5.2433 6.9372
BC-3C CTRP2 5.3825 6.5383 5.2304 6.7955
SW780 GDSC1 5.6181 7.4715 2.71 0.5389
UM-UC-3 GDSC1; CTRP2 5.73 7.3178 5.2731 5.6967
HT-1197 GDSC1; CTRP2 5.7385 7.169 5.35 5.3662
253J CTRP2 5.7699 7.1729 5.3797 5.1679
CAL-29 GDSC1; CTRP2 6.1616 7.8671 5.412 4.142
TCCSUP GDSC1; CTRP2 6.2403 8.9289 4.9498 5.9214
HT-1376 GDSC1; CTRP2 6.2764 7.9696 5.4599 3.7087
KMBC-2 CTRP2 6.3719 8.8693 5.0897 5.8654
T24 GDSC1; GDSC2; CTRP2 6.4166 8.7075 5.207 4.5025
253J-BV CTRP2 6.4231 8.9437 5.0944 4.9629
UM-UC-1 CTRP2 6.588 8.058 5.6644 2.2886
KU-19-19 GDSC1; CTRP2 7.4169 10.3991 5.1078 3.3335
639V GDSC1; CTRP2 7.8791 8.9331 5.9802 0.1219
VM-CUB-1 CTRP2 8.0513 12.5819 4.4892 4.9263
647V GDSC1; CTRP2 8.504 10.0562 5.8164 0.2095
J82 GDSC1; CTRP2 8.7896 11.8755 5.2322 1.4879
SCaBER CTRP2 8.8526 10.3868 5.8287 0.1223
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PA-1 GDSC1 2.2626 6.1654 -0.3413 10.2928
SKN GDSC1 2.6927 5.2649 1.7867 11.7139
OVMIU GDSC1 2.9204 7.0228 1.1271 14.9968
PWR-1E GDSC1 3.2062 7.1222 1.3245 15.9116
ACC-OV7 GDSC1; GDSC2 3.2387 6.4096 1.7082 10.446
KGN GDSC1 3.3051 7.284 1.3268 12.6054
NEC8 GDSC1 3.4166 5.3306 2.3954 5.5963
SW756 GDSC1 3.5672 5.3055 2.5264 4.3669
OVCA433 GDSC1; GDSC2 3.5852 6.8465 1.774 9.0465
NCC-IT GDSC1 3.6202 5.5511 0.7142 0.8051
HEY GDSC1 3.6392 7.7598 1.3615 14.0735
TC-YIK GDSC1 3.6464 5.7933 2.3451 6.603
SiHa GDSC1 3.7733 8.1096 1.2931 11.4901
Ca Ski GDSC1 3.7842 6.0609 2.316 5.1436
JAR GDSC1; GDSC2 3.8235 5.3811 2.6744 2.8502
NT2-D1 GDSC1 3.9962 5.8158 2.5822 3.0474
JHOS-3 GDSC1; GDSC2 4.1636 6.6362 2.3028 4.3757
MS751 GDSC1 4.3161 7.9972 1.7521 7.3694
BPH-1 GDSC1 4.346 9.9535 0.8161 12.7813
HT-3 GDSC1 4.4168 22.7601 -5.5005 33.005
HEC-1 GDSC1 4.4353 6.9941 2.31 3.7999
SKG-IIIa GDSC1 4.5503 6.4291 2.6332 1.8301
CAL-39 GDSC1 4.8736 6.8919 2.6041 1.5618
SiSo GDSC1 4.929 7.8278 2.2255 3.4284
OV17R GDSC1; GDSC2 5.0173 7.1782 2.5562 1.6199
LB831-BLC GDSC1 5.179 11.5994 0.61 11.9544
PEO1 GDSC1 5.2565 7.3926 2.5838 1.5567
C-4-I GDSC1 5.3244 7.1216 2.7204 0.6805
DSH1 GDSC1 5.4139 7.6071 2.5705 1.1615
SW962 GDSC1; GDSC2 5.6767 7.1782 2.8374 0.2152
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 5.6855 7.3819 2.7689 0.3545
UWB1.289 GDSC1; GDSC2 5.7109 8.0332 2.5356 1.0524
JEG-3 GDSC1; GDSC2 5.7562 7.3035 2.8228 0.2194
ME-180 GDSC1 5.7731 7.88 2.6208 0.719
SW954 GDSC1; GDSC2 5.8063 7.6377 2.7233 0.4141
OVCA420 GDSC1 5.8341 7.7876 2.6797 0.64
C-33 A GDSC1 5.8555 7.8957 2.6485 0.5895
HeLa GDSC1; CTRP2 6.2984 9.3531 4.7867 6.4922
DoTc2 4510 GDSC1 6.6333 15.8963 -0.4659 14.1137
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

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