Details of the Drug

General Information of Drug (ID: DMBE24Y)

Drug Name
PF750
Synonyms PF-750; PF 750
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 345.4
Logarithm of the Partition Coefficient (xlogp) 4.1
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 2
Chemical Identifiers
Formula
C22H23N3O
IUPAC Name
N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide
Canonical SMILES
C1CN(CCC1CC2=CC3=CC=CC=C3N=C2)C(=O)NC4=CC=CC=C4
InChI
InChI=1S/C22H23N3O/c26-22(24-20-7-2-1-3-8-20)25-12-10-17(11-13-25)14-18-15-19-6-4-5-9-21(19)23-16-18/h1-9,15-17H,10-14H2,(H,24,26)
InChIKey
BIODYGOZWZNCAG-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
25154868
ChEBI ID
CHEBI:95037
CAS Number
959151-50-9
TTD ID
D0W0SE

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fatty acid amide hydrolase (FAAH) TTDP1UC NOUNIPROTAC Inhibitor [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Fatty acid amide hydrolase (FAAH) DTT NO-GeName 2.65E-01 0.02 0.1
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 119 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 5.0508 7.1236 4.8422 14.9003
MEC1 CTRP2 6.2685 9.1949 5.7156 14.0647
JM1 CTRP2 4.9929 8.0288 4.7242 21.4616
Peer CTRP2 4.1921 5.4659 4.1907 25.86
SK-MM-2 CTRP2 4.2067 9.3898 3.4338 28.4023
Daudi CTRP2 4.4176 7.0553 4.3088 24.7243
SU-DHL-5 CTRP1 4.4537 7.1551 4.3292 51.3374
GA-10 CTRP2 4.484 6.8699 4.4074 24.1719
KMS-34 CTRP2 4.4871 5.5272 4.4866 23.8939
HEL 92.1.7 CTRP2 4.5008 6.0782 4.491 23.8335
SR CTRP2 4.5084 7.3231 4.3594 24.2596
DEL CTRP2 4.562 5.0113 4.562 23.3936
SET-2 CTRP2 4.6175 8.7624 4.0943 24.8584
KMS-11 CTRP2; CTRP1 4.6204 8.8327 4.0742 24.9211
JeKo-1 CTRP2 4.6266 6.8405 4.563 23.1789
BL-41 CTRP2 4.6676 10.7009 3.4154 27.065
LP-1 CTRP2; CTRP1 4.6959 7.2244 4.58 22.8977
SU-DHL-1 CTRP2 4.7569 5.7631 4.7563 22.0983
RPMI-8402 CTRP2 4.7907 6.2894 4.7797 21.9083
NU-DUL-1 CTRP2; CTRP1 4.7908 5.7056 4.7905 21.7784
OCI-AML-3 CTRP2; CTRP1 4.792 8.0133 4.5091 22.8465
MOLM-16 CTRP2; CTRP1 4.8782 7.6916 4.6807 21.8777
CML-T1 CTRP2 4.9167 6.4268 4.903 21.0785
Ku812 CTRP2; CTRP1 4.9505 7.2457 4.8506 21.1481
MOLT-16 CTRP2 4.9629 5.8173 4.9591 14.7555
KM-H2 CTRP2 5.0679 8.0767 4.7931 22.4513
L-540 CTRP2 5.0984 6.3581 5.0597 13.9128
KMM-1 CTRP2 5.1113 9.09 4.5165 21.8636
ST486 CTRP2 5.1472 9.7022 4.3251 22.4638
KMS-18 CTRP2 5.177 6.9237 5.1367 19.4363
Ri-1 CTRP2 5.1833 7.1362 4.9832 13.9206
U-937 CTRP2; CTRP1 5.2067 8.0015 4.9648 19.9454
NALM-6 CTRP2 5.2099 7.5536 5.0738 19.5486
SU-DHL-6 CTRP2 5.3142 7.1432 5.1239 12.9472
RCH-ACV CTRP2 5.3526 6.6761 5.2816 12.214
A4/Fukuda CTRP2 5.3555 8.9891 4.8159 20.0473
RL CTRP2 5.3558 7.989 5.1308 18.8938
TALL-1 [Human adult T-ALL] CTRP2 5.3848 7.5181 5.2705 18.3089
HuT 78 CTRP2 5.3932 8.2523 5.0984 18.8973
PL21 CTRP1 5.4588 7.6632 5.3187 38.0026
THP-1 CTRP2; CTRP1 5.4602 8.4679 5.1056 18.6707
BL-70 CTRP1 5.4756 6.6081 4.598 2.7126
HD-MY-Z CTRP2 5.4797 8.6486 5.0681 18.7511
MM1.S CTRP2 5.5204 7.5648 5.4082 17.3996
SU-DHL-4 CTRP2; CTRP1 5.5374 8.7603 5.088 18.4124
MOLM-6 CTRP2 5.5681 7.619 5.2401 11.6861
RS4;11 CTRP2 5.5819 7.7578 5.4341 17.1155
HH [Human lymphoma] CTRP2 5.6285 10.0637 4.6865 19.7662
Jurkat CTRP2 5.6591 8.1456 5.4192 18.116
A3/Kawakami CTRP2 5.7411 7.956 5.5597 16.1769
Mono-Mac-1 CTRP2 5.8398 7.7767 5.7104 15.3355
Toledo CTRP2 5.8443 10.2552 4.8296 18.6354
OCI-AML-5 CTRP2 5.9161 7.5756 5.8343 14.6607
OPM-2 CTRP2 5.971 8.9357 5.4979 15.727
GDM-1 CTRP1 5.9896 7.6874 5.8901 30.2765
SKM-1 CTRP1 5.9933 8.0856 5.7973 30.9041
Karpas-620 CTRP2 6.0055 8.9746 5.5204 15.5438
NU-DHL-1 CTRP2 6.0125 7.9355 5.8609 14.2659
BV-173 CTRP2 6.0134 8.4572 5.7107 14.809
Kasumi-2 CTRP2 6.0358 8.1727 5.8225 14.333
KMS-20 CTRP2 6.0555 9.1261 5.5163 15.4191
HPB-ALL CTRP2 6.0562 7.4247 6.0094 13.6071
KHM-1B CTRP2 6.0813 7.3975 6.04 13.4213
KMS-12-BM CTRP2 6.1 7.9868 5.9434 13.702
WSU-DLCL2 CTRP2; CTRP1 6.1739 7.4035 6.1378 12.7874
LAMA-84 CTRP2 6.2011 11.3738 4.6881 19.5006
KMS-27 CTRP2 6.2259 8.386 5.9647 13.2457
SUP-T11 CTRP2 6.2509 7.5142 6.2048 12.3095
F-36P CTRP2 6.2667 8.9404 5.813 13.6973
L-428 CTRP2 6.2881 8.4732 6.0038 12.9187
TF-1 CTRP2 6.3076 9.1305 5.7828 13.6988
K-562 CTRP2 6.3259 9.327 5.7229 13.8793
RPMI-8226 CTRP1 6.3425 10.1574 5.3766 31.2111
EJM CTRP2; CTRP1 6.3468 10.9953 5.0081 16.6367
KE-97 CTRP2; CTRP1 6.3895 8.0534 6.2417 11.7463
NOMO-1 CTRP1 6.4008 7.5882 6.3527 24.0384
MHH-CALL-3 CTRP2 6.4363 8.6743 6.0939 12.1534
AML-193 CTRP2 6.4595 8.095 6.3068 11.2985
CA46 CTRP2 6.4641 10.0395 5.5606 14.1499
SU-DHL-8 CTRP2 6.4674 8.6719 5.6993 7.2355
OCI-Ly3 CTRP2 6.4853 9.691 5.7355 13.4041
U266B1 CTRP2 6.4986 8.7048 6.1498 11.7655
KCL-22 CTRP2 6.5049 12.849 4.2808 19.0739
EB1 CTRP2 6.5175 9.1969 5.9777 12.3719
HEL CTRP2 6.5246 8.6444 6.1999 12.3066
KYO-1 CTRP2 6.5361 8.1635 6.3709 10.835
AMO1 CTRP2; CTRP1 6.5597 7.7552 6.4946 10.2137
Namalwa CTRP2 6.5755 9.8503 5.7582 13.0795
L-363 CTRP2 6.5782 7.2759 6.5726 9.9933
M-07e CTRP2 6.5995 9.1099 6.0996 11.6765
JVM-3 CTRP2 6.6125 8.2158 6.4387 10.3587
KMS-28BM CTRP2 6.6148 7.8105 6.5453 21.3784
HDLM-2 CTRP2 6.6158 9.4689 5.9662 12.1535
MHH-CALL-4 CTRP2 6.6699 8.2294 6.1048 4.9378
HT CTRP2; CTRP1 6.7109 8.0893 6.5828 9.5392
Hs 611.T CTRP2 6.7312 10.0644 5.8196 12.4377
DND-41 CTRP2 6.8073 9.1279 6.3101 10.2972
P31/FUJ CTRP2 6.8107 8.1069 6.6868 8.8608
REC-1 CTRP2 6.8721 9.9347 6.0202 11.2795
MOLP-2 CTRP2 6.8948 8.6418 6.5982 8.9458
MC116 CTRP2; CTRP1 6.9391 8.823 6.0518 4.5592
SUP-HD1 CTRP2 6.97 10.4079 5.8966 11.5383
Granta-519 CTRP2 7.175 10.1429 6.2214 9.7241
P3HR-1 CTRP2; CTRP1 7.2041 8.6252 6.3669 2.604
JJN-3 CTRP2 7.2138 8.5761 6.9636 6.6602
SEM CTRP2 7.2398 8.1349 7.1468 5.8981
OCI-M1 CTRP2 7.2999 9.3324 6.7241 7.3806
SIG-M5 CTRP2 7.3323 7.9282 7.2995 5.0679
SUP-B15 CTRP2 7.3945 10.6089 6.2052 9.2817
KO52 CTRP2 7.4075 12.0095 5.5282 12.0523
MOTN-1 CTRP2 7.5752 8.4485 7.397 3.9976
OCI-Ly19 CTRP2 7.5848 9.0779 7.1242 5.0625
Karpas-422 CTRP2 7.6455 8.1005 7.5995 3.0324
Ci-1 CTRP2 7.7595 8.1721 7.7004 2.324
CMK CTRP2 8.1384 11.5797 6.3764 7.0221
SU-DHL-10 CTRP2 8.2329 9.2473 6.6859 0.2318
OCI-Ly10 CTRP2; CTRP1 9.0161 13.7575 5.9762 7.1581
RPMI-6666 CTRP2 9.7261 10.994 7.6605 0.2142
Kasumi-1 CTRP2 10.0658 13.4701 6.8019 2.5214
⏷ Show the Full List of 119 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 6.8478 10.8425 5.572 13.1496
TE8 CTRP2 7.1531 8.729 6.8379 7.3112
TE-5 CTRP2 4.933 10.3619 3.8338 24.852
KYSE-510 CTRP2 5.605 7.2589 5.5506 16.6363
EC-GI-10 CTRP2 5.8079 11.1423 4.4005 20.3704
KYSE-30 CTRP2 6.5142 9.0356 6.0395 12.1423
TE-6 CTRP2 6.8121 8.2612 6.6421 9.0197
KYSE-180 CTRP2 6.8778 8.6973 6.5586 9.1442
KYSE-410 CTRP2; CTRP1 6.891 9.366 6.2946 10.1368
TE-14 CTRP2 6.8959 19.6262 1.2907 27.476
TE-10 CTRP2 7.0305 11.516 5.4228 13.3268
TE-1 CTRP2 7.1102 11.1079 5.6958 12.0276
KYSE-140 CTRP2; CTRP1 7.1425 9.6081 6.4402 8.9153
OE21 CTRP2 7.179 12.0183 5.3156 13.4269
TE-4 CTRP2 7.2141 11.0446 5.8243 11.2621
TE-11 CTRP2 7.257 10.1255 6.3088 9.1724
KYSE-70 CTRP2 7.3919 10.0334 6.4821 8.1458
TE-9 CTRP2 7.4281 11.1081 5.9916 10.0909
KYSE-150 CTRP2 7.4537 9.7473 6.6787 7.1945
OE33 CTRP2 8.0663 12.9497 4.8773 7.7071
OE19 CTRP2 8.1258 12.1246 5.322 5.6671
KYSE-450 CTRP2; CTRP1 8.4657 13.2821 5.7907 8.863
COLO 680N CTRP2 9.133 11.9608 6.9288 3.1242
KYSE-520 CTRP2 9.9588 15.2424 5.9149 6.0121
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 7.8936 11.5488 5.4378 5.5377
HuP-T4 CTRP2; CTRP1 5.7826 7.8589 5.6291 15.8012
MIA PaCa-2 CTRP2 6.0087 8.9591 5.5296 15.5003
PaTu 8988s CTRP2 6.0461 10.6445 4.8655 17.9637
PSN1 CTRP2 6.1709 8.1736 5.9696 13.3923
Capan-2 CTRP2; CTRP1 6.2623 8.0913 6.0926 12.6703
KP-3 CTRP2; CTRP1 6.2894 10.3073 5.2635 15.7745
KP-4 CTRP2 6.3945 8.2263 6.198 11.8893
SW1990 CTRP2 6.4881 10.5789 5.3407 14.9623
Panc 03.27 CTRP2; CTRP1 6.5768 8.0701 6.4417 10.4555
HPAF-II CTRP2 6.6022 9.9884 5.7238 13.1471
HPAC CTRP2; CTRP1 6.6381 8.3442 6.4263 10.3286
SU.86.86 CTRP2 6.6602 7.4556 6.646 9.4762
PK-59 CTRP2 6.9807 9.6523 6.2579 10.053
Panc 10.05 CTRP2; CTRP1 7.0682 9.5247 6.404 9.2471
Panc 04.03 CTRP2 7.0873 9.4421 6.4607 8.9718
L3.3 CTRP2 7.1463 10.8291 5.8649 11.2511
BxPC-3 CTRP2 7.1748 9.8739 6.3484 9.2077
SNU-213 CTRP2 7.2398 8.4115 7.0542 6.2419
SNU-410 CTRP2 7.2749 9.1909 6.7637 7.2843
QGP-1 CTRP2; CTRP1 7.3174 9.0682 6.8619 6.7842
HuP-T3 CTRP2 7.3751 8.8873 7.0012 6.0816
Panc 08.13 CTRP2 7.4195 9.7011 6.6681 7.3184
CFPAC-1 CTRP2; CTRP1 7.4255 10.2334 6.4171 8.3361
Hs 766T CTRP2 7.4595 10.9728 6.0869 9.6268
TCC-Pan2 CTRP2 7.4857 9.9454 6.6136 7.3881
KP-2 CTRP2 7.5077 14.5541 4.3525 16.5386
Capan-1 CTRP2 7.6163 8.5764 7.3851 3.9351
DAN-G CTRP2 7.6304 8.9273 7.2397 4.4829
Panc 02.03 CTRP2 7.8272 10.6248 6.5892 6.7454
PK-45H CTRP2 8.3226 16.4017 4.1174 15.7773
PaTu 8902 CTRP2; CTRP1 8.3533 10.0239 7.323 2.6706
YAPC CTRP2 8.8437 11.3162 7.0431 3.066
AsPC-1 CTRP2 9.1347 17.8362 4.0483 14.5334
PaTu 8988t CTRP2 9.3179 11.2668 7.3588 1.3021
SUIT-2 CTRP2; CTRP1 10.1047 11.7619 7.5288 0.3301
Panc 05.04 CTRP2 10.1524 23.3567 2.0902 19.1514
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 6.6775 18.1726 1.8201 26.6186
WM115 CTRP2 4.0169 6.5936 3.9455 27.262
COLO 792 CTRP2 5.5415 7.4278 5.4563 17.1647
SK-MEL-5 CTRP2; CTRP1 5.6738 7.1811 5.6337 16.1292
G-361 CTRP2; CTRP1 5.6931 7.0849 5.6643 15.9624
SK-MEL-1 CTRP2; CTRP1 6.1845 7.5664 6.1253 12.7963
Hs 944.T CTRP2; CTRP1 6.3649 7.6411 6.0759 5.8677
MDA-MB-435S CTRP2 6.4053 7.8208 6.3156 11.434
COLO 741 CTRP2; CTRP1 6.6392 10.2273 5.653 13.336
HMCB CTRP2 6.6672 8.4844 6.4107 10.3015
SK-MEL-31 CTRP2 6.7064 8.2414 6.5333 9.7326
A-375 CTRP2; CTRP1 6.7332 7.8288 6.67 9.1597
RVH-421 CTRP2 6.7501 9.2526 6.1979 10.8882
MeWo CTRP2 7.0057 9.7579 6.2348 10.0833
Mel JuSo CTRP2 7.0154 10.1016 6.0851 10.6636
RPMI-7951 CTRP2 7.0864 8.4086 6.89 7.2985
Hs 852.T CTRP2; CTRP1 7.2286 9.5436 6.5557 8.2365
Hs 940.T CTRP2 7.2346 9.0624 6.7803 7.3213
HT-144 CTRP2 7.2661 8.7085 6.9651 6.5112
IGR-37 CTRP2 7.34 8.622 7.0784 5.8711
LOX-IMVI CTRP2 7.3415 10.4747 6.2209 9.3371
UACC-257 CTRP2 7.41 13.902 4.5914 15.823
SK-MEL-3 CTRP2 7.4432 8.0354 7.3962 4.3805
Hs 294T CTRP2 7.4702 8.031 7.4267 4.1886
IGR-1 CTRP2 7.5022 8.4329 7.3262 4.4705
WM983B CTRP2 7.6064 9.1943 7.09 5.1499
IPC-298 CTRP2 7.629 9.2542 7.0832 5.1248
SK-MEL-24 CTRP2 7.7018 12.8115 5.3901 11.9985
COLO 829 CTRP2 7.7424 8.4265 7.5803 2.8349
Hs 839.T CTRP2 7.7477 8.1735 7.6873 2.407
A2058 CTRP2 7.8017 8.3587 7.6709 2.322
A101D CTRP2 7.9176 8.4618 7.7396 1.7562
WM793 CTRP2 8.0768 10.5123 6.8591 5.1137
WT2-iPS CTRP2 8.2073 11.3525 6.5464 6.1791
SK-MEL-28 CTRP2; CTRP1 8.2471 11.6394 6.4353 6.5713
Hs 688(A).T CTRP2 8.3126 12.2764 6.1701 7.5613
Hs 895.T CTRP2 8.3584 10.8877 6.8986 4.4306
K029AX CTRP2 8.4202 11.1185 6.8319 4.6021
WM1799 CTRP2 8.5643 11.4897 6.7577 4.6673
SK-MEL-30 CTRP2 8.6253 14.7204 5.2003 10.995
COLO 800 CTRP2 9.027 12.678 6.512 4.9489
IGR-39 CTRP2 9.1556 10.3206 7.6757 0.4336
Hs 936.T CTRP2; CTRP1 9.5237 11.0251 7.5632 0.5168
Mel Ho CTRP2 10.2892 12.0675 7.4899 0.3392
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 6.7962 9.8932 5.9628 11.7002
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHP-212 CTRP2 4.9851 8.454 4.5927 21.959
SK-N-BE(2) CTRP2 6.3878 8.9964 5.9206 12.9482
KP-N-YN CTRP2 6.7003 9.5764 6.0067 11.7721
CHP-126 CTRP2 7.099 11.1349 5.0296 8.8359
SK-N-SH CTRP2 7.3863 9.8329 6.5731 7.7857
SK-N-AS CTRP2 7.5366 8.2386 7.4363 3.9553
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 3.6598 11.302 2.1093 34.0573
SNU-478 CTRP2 6.7204 8.4706 6.4729 9.9153
HuH-28 CTRP2 6.7967 7.729 6.7571 8.6548
SNU-1196 CTRP2 7.1952 9.4311 6.5742 8.245
SNU-308 CTRP2 7.4387 10.085 6.5015 7.9577
SNU-869 CTRP2 7.5509 13.7624 4.7847 14.762
HuCC-T1 CTRP2 9.8933 11.4553 7.557 0.3539
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-78 CTRP2 2.1718 40.0419 -13.0591 47.7064
MG-63 CTRP2 3.5094 4.5759 3.5093 30.3996
SK-N-MC CTRP2 5.6321 7.6437 5.5134 16.679
A-673 CTRP2 5.8111 8.2393 5.558 15.9704
HOS CTRP2 6.1118 8.0408 5.942 13.6708
MHH-ES-1 CTRP2 6.4196 8.2089 6.2305 11.6955
SK-ES-1 CTRP2 6.8866 9.0163 6.4396 9.5792
TC71 CTRP2 7.3679 9.052 6.9203 6.4225
SaOS-2 CTRP2 7.7786 10.894 6.4126 7.5853
Hs 888.T CTRP2 7.908 10.1581 6.8924 5.3093
SJSA-1 CTRP2 7.9947 10.8025 6.6449 6.1731
SW1353 CTRP2 8.111 10.4501 6.9186 4.7983
G-292 clone A141B1 CTRP2 8.1728 10.5322 6.9282 4.6414
U2OS CTRP2; CTRP1 8.4213 16.1558 4.3207 14.8254
⏷ Show the Full List of 14 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 66 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1500 CTRP2 5.2084 11.1628 3.7801 24.2618
HCC1143 CTRP2 5.4033 9.2728 4.7632 20.1063
HCC1419 CTRP2 5.4227 9.7388 4.603 20.6514
MDA-MB-453 CTRP2 5.4444 8.0092 5.2221 18.2953
Hs 578T CTRP2 5.6206 12.7032 3.4954 24.1352
BT-20 CTRP2 5.7394 10.4738 4.6268 19.6928
T-47D CTRP2 5.8289 9.1525 5.2642 17.0129
MDA-MB-361 CTRP2 5.845 14.0169 3.09 24.9015
MCF-7 CTRP2; CTRP1 5.9032 9.3994 5.2472 16.8704
MDA-MB-468 CTRP2 6.1085 8.9175 5.6522 14.7537
BT-474 CTRP2 6.1964 8.4819 5.9013 13.5671
AU565 CTRP2 6.2094 9.7536 5.4228 15.3596
SK-BR-3 CTRP2 6.411 8.8452 6.0035 12.5674
CAMA-1 CTRP2 6.456 9.0901 5.9561 12.6234
HMC-1-8 CTRP2 6.5048 8.1183 6.3498 11.0059
HCC1395 CTRP2 6.6417 9.8688 5.8175 12.6736
HCC202 CTRP2 6.7848 13.3183 3.6743 15.4116
HCC1954 CTRP2 6.8245 16.5874 2.7376 23.6551
CAL-51 CTRP2 6.845 9.4309 6.219 10.5554
HCC1937 CTRP2 7.0345 14.2931 4.0624 18.6649
MDA-MB-415 CTRP2 7.0379 11.5349 5.4206 13.3188
HCC1428 CTRP2 7.1212 11.389 5.5697 12.5192
CAL-85-1 CTRP2 7.359 10.9522 6.0044 10.1918
MDA-MB-157 CTRP2 7.6565 9.834 6.8273 6.1181
HCC1806 CTRP2 7.6804 9.2848 7.1173 4.8648
EFM-192A CTRP2 7.8272 11.0582 6.3733 7.6495
HCC38 CTRP2 8.0095 9.5777 7.2696 3.5216
BT-549 CTRP2 8.1423 12.4795 5.9298 8.8841
Hs 578Bst CTRP2 8.4953 13.2449 5.8327 8.6358
KPL-1 CTRP2 8.8166 9.4619 7.8617 0.1514
JIMT-1 CTRP2 9.6321 13.1859 6.6728 3.4848
ZR-75-1 CTRP2 9.735 11.8128 7.3429 1.005
HDQ-P1 CTRP2 9.9269 11.717 7.4711 0.5326
MDA-MB-231 CTRP2 10.9019 29.5208 -0.3914 23.9959
BT 416 CTRP2 5.284 7.8198 5.0951 19.2424
BT 145 CTRP2 5.5892 12.0891 3.7492 23.3348
BT147 CTRP2 5.8612 9.4291 5.1909 17.2016
BT 231 CTRP2 6.005 8.447 5.7049 14.8552
BT 172 CTRP2 6.5366 9.1735 6.0074 12.2051
BT 428 CTRP2 6.5781 8.6779 6.2451 11.1794
BT 245 CTRP2 6.6538 10.1 5.7256 13.009
BT 248 CTRP2 6.8105 9.7318 6.0502 11.3152
BT 228 CTRP2 7.0023 10.3852 5.9388 11.2892
BT 504 CTRP2 7.0509 9.5558 6.3724 9.4172
BT 286 CTRP2 7.0596 9.5388 6.3889 9.329
BT 232 CTRP2 7.1225 11.4193 5.5562 12.5714
BT 216 CTRP2 7.2649 17.5217 2.6618 22.9097
BT 271 CTRP2 7.284 9.849 6.4667 8.4634
BT 139 CTRP2 7.302 8.2121 7.1907 5.5522
BT 444 CTRP2 7.4325 11.5127 5.7963 10.8908
BT 440 CTRP2 7.4868 9.458 6.8489 6.4195
BT 131 CTRP2 7.5581 8.9614 7.1523 5.0139
BT 330 CTRP2 7.5816 10.2031 6.5772 7.322
BT 159 CTRP2 7.6097 9.2959 7.0447 5.3278
BT 359 CTRP2 7.6527 10.1042 6.6911 6.692
BT 179 CTRP2 7.653 10.8532 6.3213 8.2314
BT164 CTRP2 8.0289 11.5281 6.3111 7.5069
BT 482 CTRP2 8.0326 9.6084 7.2739 3.4579
BT 333 CTRP2 8.0411 10.9952 6.5877 6.3223
BT 422 CTRP2 8.0787 11.2842 6.4747 6.7238
BT 340 CTRP2 8.3904 11.007 6.8641 4.5189
BT 328 CTRP2 8.421 11.8091 6.4892 6.0316
BT 498 CTRP2 8.6449 17.3023 3.9285 15.8584
BT 112 CTRP2 8.6899 13.5248 5.8454 8.2407
BT 224 CTRP2 8.9871 14.681 4.6807 7.0882
BT 320 CTRP2 9.3606 14.5534 5.836 7.1882
⏷ Show the Full List of 66 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 9.3947 13.2709 6.479 4.5526
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TM-31 CTRP2 4.4485 4.8449 4.4485 24.1487
Daoy CTRP2 4.4981 4.9859 4.4981 23.8191
ONS-76 CTRP2 4.5337 4.9928 4.5337 23.5822
GB-1 CTRP2 4.553 4.9949 4.553 23.4538
T98G CTRP2 4.8737 7.4636 4.7274 21.8207
SF126 CTRP2 5.417 6.8586 5.3946 17.7779
U-251MG CTRP2 5.4722 7.3639 5.3924 17.6073
SNU-466 CTRP2 6.346 8.9254 5.9035 13.1302
SF268 CTRP2 6.4807 10.2996 5.4607 14.5037
8-MG-BA CTRP2 6.489 8.3972 6.247 11.4292
U-87MG ATCC CTRP2 6.7818 9.2584 6.2284 10.6846
KNS-60 CTRP2 6.8036 8.5804 6.5234 9.4872
LN-18 CTRP2 6.8767 8.7709 6.5289 9.2612
SF539 CTRP2 6.8818 10.2901 5.8654 11.8791
LN-229 CTRP2; CTRP1 6.9438 9.1884 6.4263 9.479
GaMG CTRP2; CTRP1 7.0459 8.8762 6.6648 8.2734
SF295 CTRP2; CTRP1 7.2508 10.4649 6.1399 9.8797
A-172 CTRP2 7.5134 9.2122 6.9911 5.7763
U-118MG CTRP2 7.548 9.1479 7.0553 5.4316
KG-1-C CTRP2 7.5963 8.4309 7.4263 3.8265
Hs 683 CTRP2 7.6372 8.3532 7.501 3.4263
Becker CTRP2 7.7154 11.1977 6.2058 8.5816
42-MG-BA CTRP2 7.8374 12.3885 5.7183 10.3646
KALS-1 CTRP2 7.8926 11.3212 6.2986 7.8294
YH-13 CTRP2 7.8972 9.7255 7.0984 4.4688
M059K CTRP2 7.9193 8.8842 7.5354 2.5969
GMS-10 CTRP2 8.1015 9.0965 7.5873 2.0084
SW1088 CTRP2 8.1651 11.1163 6.63 5.9075
YKG-1 CTRP2 8.2235 13.727 5.373 11.0356
CAS-1 CTRP2 8.3476 10.2405 7.2116 3.1436
DK-MG CTRP2 8.4711 11.3579 6.7522 4.847
SNB-75 CTRP2 8.5951 14.8257 5.124 11.3577
SNU-1105 CTRP2 8.9155 11.2924 7.1028 2.7274
KNS-81 CTRP2 9.1176 10.4057 7.6228 0.6106
SNU-626 CTRP2 9.3778 13.3879 6.4116 4.8446
CCF-STTG1 CTRP2 9.5353 16.0365 5.2373 9.3139
SNU-489 CTRP2 9.547 20.2557 3.165 16.8782
DBTRG-05MG CTRP2 10.5935 12.2912 7.5265 0.1942
GOS-3 CTRP2 11.4994 17.5759 5.7853 4.6649
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-265 CTRP2; CTRP1 3.5369 4.5691 3.5369 30.2163
HEC-151 CTRP2; CTRP1 4.1465 5.9775 4.1317 26.2083
HEC-50B CTRP2 4.4642 5.6429 4.4551 18.3442
HEC-1-A CTRP2 5.5538 7.8579 5.3799 17.3953
HEC-6 CTRP1 5.5693 7.0434 4.453 3.6745
HEC-251 CTRP2; CTRP1 5.8062 6.5611 5.8053 15.1156
JHUEM-3 CTRP2 6.1944 15.6517 2.6253 25.4799
JHUEM-2 CTRP2; CTRP1 6.2414 7.8854 6.1226 13.5104
MFE-319 CTRP2; CTRP1 6.3337 8.946 5.8824 13.2449
AN3-CA CTRP2 6.3371 9.3036 5.7442 13.7663
RL95-2 CTRP2 6.4477 9.8421 5.631 13.9142
HEC-108 CTRP2; CTRP1 6.6277 8.1869 6.4639 10.2214
HEC-1-B CTRP2 6.6528 9.6068 5.9446 12.1411
HEC-59 CTRP2; CTRP1 6.7195 8.4477 6.4799 9.8919
MFE-296 CTRP2 6.7711 9.5401 6.0953 11.2372
KLE CTRP2; CTRP1 6.8302 9.1689 6.3168 10.2096
JHUEM-7 CTRP2 7.0852 11.503 5.4805 12.9658
EN CTRP2 7.2819 13.1341 4.8585 15.0452
ESS-1 CTRP2 7.351 11.2599 5.8462 10.8637
EFE-184 CTRP2 8.1362 10.6652 6.8318 5.1149
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 5.9508 6.7898 5.9479 14.16
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UO-31 CTRP2 4.69 7.1938 4.579 22.9199
TUHR14TKB CTRP2 5.5466 15.0038 2.3306 44.6604
ACHN CTRP2 5.6303 7.532 5.5334 16.615
OS-RC-2 CTRP2 5.9912 8.0297 5.8134 14.5014
SNU-1272 CTRP2 6.0189 8.0032 5.8507 14.2827
786-O CTRP2 6.1997 9.9524 5.3275 15.7575
Caki-1 CTRP2 6.3733 9.935 5.5138 14.5703
KMRC-20 CTRP2 6.6366 8.4206 6.3993 10.4327
TUHR10TKB CTRP2 6.6958 8.5653 5.9643 5.5015
VMRC-RCW CTRP2; CTRP1 6.8657 9.5118 6.2045 10.5595
769-P CTRP2 7.2983 8.5839 7.05 6.0947
KMRC-3 CTRP2 7.3186 9.3714 6.7247 7.332
CAL-54 CTRP2 7.4271 11.6954 5.7011 11.296
KMRC-1 CTRP2 7.6467 8.1962 7.5701 3.1372
VMRC-RCZ CTRP2 7.6734 10.9405 6.2963 8.2927
KMRC-2 CTRP2 7.7744 9.5962 7.0524 4.9229
A-498 CTRP2 7.878 10.3325 6.7793 5.8446
RCC10RGB CTRP2; CTRP1 8.0721 9.4088 7.4069 2.8222
Caki-2 CTRP2 8.8345 13.0264 6.2016 6.5252
TUHR4TKB CTRP2 9.4796 10.9455 7.5748 0.5117
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW480 CTRP1 4.2986 5.9228 4.2895 53.6524
GP2d CTRP2; CTRP1 4.6222 5.8916 4.6192 23.0029
SW620 CTRP2; CTRP1 4.9383 6.4239 4.9254 20.9324
SNU-175 CTRP1 5.1523 6.9892 5.1021 41.7975
SNU-C4 CTRP2; CTRP1 5.2335 7.3957 5.1297 19.2788
LS123 CTRP2; CTRP1 5.289 7.622 5.1454 19.0489
CW-2 CTRP2; CTRP1 5.3015 7.4115 5.1985 18.727
LS180 CTRP2; CTRP1 5.3387 7.5688 5.2105 18.6641
NCI-H747 CTRP2 5.3544 10.1475 4.3647 21.7322
SNU-407 CTRP2 5.4371 6.921 5.4105 17.6585
SW948 CTRP1 5.7909 10.486 4.6672 38.3057
HT115 CTRP2; CTRP1 5.7913 7.8246 5.6466 15.7119
LoVo CTRP2; CTRP1 5.9161 8.4077 5.6207 15.428
COLO 320 CTRP2; CTRP1 6.0314 9.8065 5.2151 16.6438
T84 CTRP2 6.1122 8.9395 5.648 14.7591
SNU-81 CTRP2; CTRP1 6.2256 8.8871 5.7892 13.9034
NCI-H508 CTRP1 6.2409 8.7862 5.8377 28.9134
SNU-C5 CTRP2; CTRP1 6.3562 8.7333 5.9862 12.7879
SW1417 CTRP2 6.3665 11.8237 4.6393 18.0334
MDST8 CTRP2; CTRP1 6.3741 8.1916 6.186 11.9941
RKO CTRP2; CTRP1 6.3752 8.1258 6.2062 11.9174
SNU-61 CTRP2; CTRP1 6.4047 9.1363 5.8833 13.0447
SNU-1040 CTRP1 6.4215 9.1214 5.9009 27.279
SNU-C2A CTRP2; CTRP1 6.4239 12.1011 4.563 18.189
COLO205 CTRP2; CTRP1 6.4437 7.3813 6.4255 10.9307
SW403 CTRP1 6.511 8.4924 4.348 2.3455
HCT 116 CTRP2; CTRP1 6.5465 8.2187 6.3659 10.8219
HT-55 CTRP2; CTRP1 6.5705 8.9534 6.1317 11.6327
C2BBe1 CTRP2; CTRP1 6.595 9.3189 6.0083 12.0436
LS513 CTRP2; CTRP1 6.7104 8.6649 6.392 10.2484
KM12 CTRP2; CTRP1 6.7609 8.654 6.4502 9.8849
HCT 8 CTRP2; CTRP1 6.864 8.3791 6.6599 8.8016
SK-CO-1 CTRP2; CTRP1 6.8782 8.7826 6.5259 9.2684
COLO201 CTRP2 6.9005 9.2945 6.3356 9.9501
SW1116 CTRP2 6.9185 11.2458 5.4473 13.4876
CL-34 CTRP1 6.925 7.9922 6.839 16.8402
COLO 678 CTRP2; CTRP1 7.1017 12.9102 4.8061 15.6519
LS411N CTRP2; CTRP1 7.1819 7.9073 7.1406 6.098
LS1034 CTRP2 7.2096 10.9844 5.8493 11.1694
CL-40 CTRP1 7.2625 9.0725 6.7965 15.1643
OUMS-23 CTRP2 7.288 9.4306 6.6669 7.6406
SW48 CTRP2; CTRP1 7.311 8.592 7.0602 6.0209
CL-11 CTRP2 7.3186 9.2275 6.7909 7.0654
HT-29 CTRP2; CTRP1 7.4081 8.4997 7.1999 5.2156
HCC-56 CTRP2 7.4126 7.945 7.3832 4.5214
RCM-1 [Human ESC] CTRP2; CTRP1 7.4232 10.0026 6.5267 7.8902
DLD-1 CTRP2; CTRP1 7.4314 8.7299 7.128 5.4338
HCT 15 CTRP2 7.4568 8.5572 7.2277 4.9757
NCI-H716 CTRP2 7.8117 12.7726 4.7757 8.5994
SNU-1033 CTRP2 8.8514 31.9636 -3.2274 31.9218
SNU-503 CTRP2 8.9892 15.8722 4.911 11.5074
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PLC/PRF/5 CTRP2 4.5416 5.9279 4.537 23.5447
HuH-6 CTRP2 4.7046 7.0071 4.6239 22.7182
SNU-886 CTRP2 5.1333 9.2707 4.4745 29.7265
SNU-398 CTRP2; CTRP1 5.2207 7.4466 5.1046 19.3106
SK-HEP-1 CTRP2 5.9821 7.8372 5.8515 14.3931
JHH-4 CTRP2 6.1485 8.896 5.7031 14.4477
JHH-1 CTRP2 6.2032 7.7404 6.1132 12.7794
JHH-2 CTRP2 6.3601 9.7813 5.5671 14.3953
Hep 3B2.1-7 CTRP2 6.4157 8.3346 6.1876 11.8643
SNU-423 CTRP2 6.5773 10.2056 5.6006 13.7014
SNU-761 CTRP2 6.6741 7.9589 6.5765 9.6742
SNU-182 CTRP2 7.0135 8.4097 6.811 7.8046
SNU-387 CTRP2 7.1841 13.4229 4.6277 16.1726
SNU-475 CTRP2 7.2838 10.6036 6.104 9.9511
HLF CTRP2 7.2923 11.8376 5.5083 12.3866
Hep-G2 CTRP2; CTRP1 7.3242 11.9611 5.4766 12.4464
HuH-1 CTRP2 7.7249 9.7045 6.9539 5.4411
JHH-6 CTRP2; CTRP1 7.7809 8.4451 7.6115 2.6112
SNU-449 CTRP2; CTRP1 8.5008 14.537 5.1929 11.2515
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 155 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H146 CTRP2 0.6203 10.1832 -0.7197 49.7406
NCI-H1963 CTRP1 1.7525 8.856 0.9434 68.9073
SCLC-21H CTRP1 1.9583 9.0079 1.1197 67.7371
NCI-H1184 CTRP2 2.0843 4.4306 -0.8134 2.0377
NCI-H446 CTRP2 3.6743 5.6945 3.6591 29.3525
NCI-H1341 CTRP2 3.8663 6.4747 3.7998 28.2476
NCI-H1568 CTRP2; CTRP1 4.1969 6.994 4.0815 26.2151
IA-LM CTRP2 4.2208 5.2024 4.2207 25.6648
NCI-H1092 CTRP2 4.333 17.4498 -0.0052 36.3299
COR-L51 CTRP1 4.3474 8.2674 3.9496 52.2755
SBC-5 CTRP2 4.45 5.0017 4.45 24.1393
NCI-H211 CTRP2 4.6297 7.0436 4.5383 23.2535
Calu-1 CTRP2 4.65 6.8549 4.5861 23.0237
SW1573 CTRP2 4.7008 8.6403 3.9175 19.7058
CAL-12T CTRP1 4.7365 7.213 4.624 47.6815
DMS 53 CTRP2 4.7537 7.6657 4.5536 22.8075
HCC44 CTRP2; CTRP1 5.0023 7.3721 4.8843 20.8661
NCI-H2029 CTRP2; CTRP1 5.0091 8.2722 4.6735 21.5945
RERF-LC-A1 CTRP2 5.1172 6.5978 5.1008 19.7533
HCC1195 CTRP2; CTRP1 5.2034 8.2285 4.8983 20.1948
NCI-H1836 CTRP1 5.2049 8.8508 4.6969 42.8041
HCC1833 CTRP2; CTRP1 5.3269 8.5638 4.9299 19.7104
DMS 454 CTRP2 5.3269 9.3534 4.6511 20.7426
NCI-H647 CTRP2 5.3945 8.1846 5.1194 18.8171
NCI-H460 CTRP2; CTRP1 5.4085 6.1797 5.4081 17.7609
Sq-1 CTRP2; CTRP1 5.5051 11.7288 3.8296 23.2746
NCI-H889 CTRP2 5.5133 6.7841 5.4339 11.0962
NCI-H2106 CTRP2 5.5334 7.9532 5.3339 17.6222
KNS-62 CTRP2; CTRP1 5.5748 6.5235 5.5722 16.6616
T3M-10 CTRP2; CTRP1 5.6154 13.6989 3.0207 25.717
NCI-H1581 CTRP2 5.6649 7.9743 5.4719 16.7246
NCI-H1105 CTRP2; CTRP1 5.6712 8.5939 5.294 17.3542
NCI-H810 CTRP1 5.6928 7.1282 4.4927 2.9985
NCI-H1755 CTRP2; CTRP1 5.7812 7.747 5.6533 15.7195
COR-L279 CTRP1 5.791 7.5452 4.36 3.8345
NCI-H1944 CTRP2; CTRP1 5.7952 9.8828 4.9364 18.3574
COR-L88 CTRP2; CTRP1 5.8022 8.7897 5.3688 16.6954
NCI-H841 CTRP2; CTRP1 5.8121 9.0782 5.2743 17.0222
COLO 668 CTRP1 5.8124 9.0005 3.6753 9.5773
NCI-H1703 CTRP2 5.8191 9.626 5.0672 17.7912
NCI-H1573 CTRP2; CTRP1 5.8231 9.7465 5.0221 17.9526
VMRC-LCD CTRP2; CTRP1 5.84 8.6777 5.4487 16.2874
NCI-H1048 CTRP1 5.847 7.5909 4.3738 3.5728
NCI-H3255 CTRP1 5.8539 11.4186 4.3133 39.0785
NCI-H2196 CTRP2 5.8712 8.9424 5.3882 16.4246
SHP-77 CTRP2; CTRP1 5.8846 8.123 5.6716 15.3365
NCI-H1155 CTRP2 5.9033 7.6768 5.8008 14.8183
NCI-H2081 CTRP2; CTRP1 5.9505 9.2882 5.3414 16.3791
NCI-H82 CTRP1 5.9522 7.3572 4.5411 2.0186
NCI-H2141 CTRP1 5.9577 12.2392 4.0353 39.2477
NCI-H2286 CTRP1 5.9807 8.7493 3.9139 7.0368
NCI-H2342 CTRP2; CTRP1 5.9921 11.1182 4.5971 19.1413
LXF 289 CTRP2; CTRP1 5.995 8.7047 5.607 15.2479
Calu-6 CTRP2; CTRP1 6.0085 7.2236 5.9829 13.8524
RERF-LC-MS CTRP2 6.0227 8.4282 5.7301 14.71
NCI-H1793 CTRP2; CTRP1 6.0257 8.5417 5.6961 14.8273
HCC1359 CTRP1 6.0331 11.0971 4.6398 36.7741
COLO 699 CTRP2; CTRP1 6.0457 8.134 5.8444 14.2238
Lu-65 CTRP2; CTRP1 6.0617 9.6789 5.3003 16.232
NCI-H2170 CTRP2 6.1256 8.6834 5.7556 14.3156
NCI-H2122 CTRP2; CTRP1 6.1431 9.2292 5.5691 14.9733
NCI-H1437 CTRP1 6.1433 8.2576 4.2474 3.8549
NCI-H1930 CTRP1 6.1593 7.698 4.5042 1.8885
EBC-1 CTRP2; CTRP1 6.17 8.3461 5.9165 13.5887
NCI-H2085 CTRP2 6.1828 9.8259 4.8715 11.6035
NCI-H1563 CTRP2 6.2056 8.3521 5.9534 13.3478
HCC2108 CTRP2; CTRP1 6.2117 9.4405 5.5562 14.835
NCI-H661 CTRP2; CTRP1 6.2759 9.123 5.2997 9.48
HCC4006 CTRP2; CTRP1 6.2792 9.3931 5.6467 14.3013
NCI-H1734 CTRP2 6.2879 10.4356 5.2045 16.011
EKVX CTRP2 6.2896 11.9495 4.505 18.7427
NCI-H2087 CTRP2 6.3171 9.0905 5.8085 13.5738
Calu-3 CTRP2; CTRP1 6.3478 8.3621 6.105 12.3693
NCI-H2228 CTRP2 6.3492 8.6029 6.0254 12.6608
NCI-H1666 CTRP2; CTRP1 6.3702 9.0401 5.8848 13.1342
NCI-H2172 CTRP2; CTRP1 6.3808 9.5801 5.6748 13.9185
NCI-H226 CTRP2 6.409 7.8404 6.3153 11.4237
NCI-H23 CTRP2; CTRP1 6.4439 9.6535 5.7088 13.618
NCI-H520 CTRP2 6.4588 10.9243 5.152 15.7866
HCC15 CTRP2; CTRP1 6.4823 9.8744 5.6522 13.7403
NCI-H2126 CTRP2; CTRP1 6.509 7.7666 6.4394 10.6735
DMS 273 CTRP2; CTRP1 6.5165 8.2203 6.3327 11.0329
PC-14 CTRP2 6.5237 8.2438 6.3335 11.0084
NCI-H2030 CTRP2; CTRP1 6.5426 10.322 5.5129 15.124
NCI-H1355 CTRP2; CTRP1 6.5876 8.6515 6.2651 11.0767
SK-MES-1 CTRP2 6.5891 10.0507 5.6826 13.3447
NCI-H596 CTRP1 6.5999 9.9539 5.7292 27.367
DV-90 CTRP2; CTRP1 6.6435 11.8244 4.9064 16.3128
RERF-LC-KJ CTRP1 6.6441 8.7181 4.3205 2.304
HCC33 CTRP1 6.7005 8.0818 4.6004 0.6365
EPLC-272H CTRP2; CTRP1 6.7217 9.1969 6.1918 10.9884
A-549 CTRP2; CTRP1 6.7302 8.4475 6.4916 9.8172
DMS 114 CTRP2 6.7385 9.5437 6.0603 11.4606
NCI-H1694 CTRP2; CTRP1 6.7704 8.9258 6.3545 10.2249
NCI-H1781 CTRP1 6.7708 9.3471 6.1718 23.0928
NCI-H1373 CTRP2; CTRP1 6.7761 9.0892 6.2937 10.4446
NCI-H1876 CTRP1 6.7839 11.643 5.1184 30.0118
NCI-H727 CTRP2; CTRP1 6.8249 9.0016 6.381 9.9737
COR-L105 CTRP2 6.8353 10.8884 5.538 13.3175
Lu-99 CTRP2; CTRP1 6.8457 8.0542 6.7394 8.5648
HCC2279 CTRP2 6.88 9.2154 6.3486 9.9531
NCI-H838 CTRP2 6.8843 10.0505 5.979 11.4147
NCI-H1975 CTRP1 6.8879 8.7411 4.4274 1.3041
HCC78 CTRP2; CTRP1 6.983 8.7194 6.662 8.4559
HOP-62 CTRP2 6.9857 12.7214 4.7926 15.9671
NCI-H2073 CTRP1 6.9941 13.5845 4.3653 32.4292
NCI-H358 CTRP2; CTRP1 6.9988 8.8174 6.6395 8.4995
LCLC-103H CTRP2; CTRP1 7.0017 8.445 6.7857 7.9335
MOR/CPR CTRP2 7.0018 8.5227 6.7575 8.0394
HCC366 CTRP2 7.0591 9.634 6.345 9.5063
NCI-H2405 CTRP2; CTRP1 7.0635 8.9811 6.6391 8.3264
HCC1588 CTRP2 7.0943 8.1509 6.9835 6.9291
NCI-H1838 CTRP2 7.1186 9.2187 6.5926 8.3661
LCLC-97TM1 CTRP2; CTRP1 7.1607 8.7678 6.83 7.3212
NCI-H441 CTRP1 7.1683 11.9249 5.3414 26.6606
NCI-H522 CTRP2; CTRP1 7.1723 11.85 5.392 13.1304
NCI-H1693 CTRP2 7.1764 9.6879 6.4369 8.845
COR-L95 CTRP2 7.185 10.2137 6.1974 9.7986
NCI-H2009 CTRP2; CTRP1 7.222 9.9314 6.3673 9.0167
LK2 CTRP2 7.2776 13.3655 4.7401 15.5251
NCI-H1915 CTRP2; CTRP1 7.2795 8.8868 6.9033 6.7177
LC-1/sq-SF CTRP2; CTRP1 7.2863 9.843 6.4717 8.4371
LUDLU-1 CTRP2 7.3079 18.1696 2.3761 23.6737
NCI-H1650 CTRP2 7.314 10.6384 6.1156 9.8341
LOU-NH91 CTRP2 7.3474 9.1663 6.2078 3.0574
NCI-H1651 CTRP2 7.3742 11.3603 5.8182 10.9281
NCI-H292 CTRP2 7.3747 8.8446 7.0197 6.0094
NCI-H1395 CTRP2 7.3786 17.8883 2.5777 22.9208
NCI-H1339 CTRP2 7.393 8.8971 7.0152 5.9801
HCC2935 CTRP2; CTRP1 7.4072 10.7588 6.1437 9.5076
NCI-H1792 CTRP2; CTRP1 7.4584 11.5759 5.7885 10.8665
NCI-H650 CTRP2; CTRP1 7.4626 9.6239 6.7465 6.8957
NCI-H322 CTRP2 7.538 9.1611 7.0392 5.5212
NCI-H2444 CTRP2 7.6245 9.4252 6.9965 5.4911
SK-LU-1 CTRP2; CTRP1 7.6378 12.1277 5.6748 10.9557
HCC95 CTRP2 7.7654 10.9569 6.3697 7.7922
NCI-H1869 CTRP2 7.771 10.3889 6.657 6.5795
SW1271 CTRP2 7.9123 9.8435 7.0528 4.6281
NCI-H1299 CTRP2; CTRP1 8.0008 11.0609 6.521 6.6812
ChaGo-K-1 CTRP2; CTRP1 8.0699 15.7744 4.2222 15.8799
BEN CTRP2; CTRP1 8.0878 9.2447 7.502 2.393
HCC827 CTRP2; CTRP1 8.2849 13.6612 5.4561 11.3013
NCI-H2023 CTRP2; CTRP1 8.6896 14.2687 5.4756 9.7619
NCI-H1435 CTRP2; CTRP1 8.75 13.0791 6.1122 7.0351
HARA [Human squamous cell lung carcinoma] CTRP2; CTRP1 8.8441 12.0786 6.6738 4.5666
HOP-92 CTRP2 8.8715 22.246 1.6431 22.6176
RERF-LC-Ad1 CTRP2 8.8945 9.7183 7.7963 0.267
NCI-H1623 CTRP2 8.896 15.7956 4.0821 9.7158
NCI-H2110 CTRP2; CTRP1 9.1261 16.9553 4.4788 12.9436
RERF-LC-Ad2 CTRP2 9.5573 14.9656 5.7747 7.1384
HCC1171 CTRP2 9.7922 17.8894 4.5164 11.6911
COR-L23 CTRP1 10.0339 20.9843 3.1592 25.7481
HCC1438 CTRP2 10.3245 18.6439 4.529 10.8204
NCI-H196 CTRP2 10.3851 16.2449 5.719 6.2078
Hs 888.Lu CTRP2 7.7108 11.6617 5.9709 9.572
⏷ Show the Full List of 155 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 6.6307 9.7376 5.8645 12.5153
Aska-SS CTRP2 9.4383 11.6409 7.2607 1.5267
TE 617.T CTRP2 3.6283 8.457 3.1131 31.3046
KYM-1 CTRP2 5.0801 6.9325 5.0332 20.1035
HT-1080 CTRP1 5.6407 6.8676 5.6262 34.6475
SK-UT-1 CTRP2 5.7182 9.8977 4.8495 18.9002
A-204 CTRP2 6.0288 9.6238 5.2886 16.3665
Hs 729.T CTRP2 6.0834 9.9949 5.189 16.6061
Rh41 CTRP2 6.1149 9.094 5.592 14.9641
G-401 CTRP2; CTRP1 6.2565 12.0852 4.4085 19.194
RKN CTRP2; CTRP1 6.3227 8.1976 6.1282 12.3589
MES-SA CTRP2 6.379 7.8548 6.2795 11.6438
Rh18 CTRP2 6.4439 8.0307 6.3071 11.3451
TTC-709 CTRP2 6.9784 9.8996 6.1423 10.5234
GCT CTRP2 7.066 9.5549 6.3881 9.3161
SK-LMS-1 CTRP2 7.1093 10.365 6.0521 10.5715
TE 441.T CTRP2 7.3695 8.8383 7.0171 6.0332
RD CTRP2 7.4286 12.4179 5.345 12.7593
G-402 CTRP2 7.5035 11.899 5.6691 11.2636
Tm87-16 CTRP2 8.1777 12.4181 5.9897 8.5669
BT-12 CTRP2 8.6108 9.7634 7.6261 1.077
BT-16 CTRP2 9.5269 12.8053 6.7841 3.1866
SW982 CTRP2 9.9752 11.0943 7.7177 0.0806
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 7.3021 10.5086 6.1674 9.6481
COV434 CTRP1 4.3623 6.6043 4.3092 52.6318
TOV-21G CTRP2 4.5081 5.083 4.5081 23.752
ES2 CTRP2 4.5561 4.9712 4.5561 23.4327
A2780 CTRP2; CTRP1 4.907 8.5071 4.4911 22.5612
OVCAR-8 CTRP2; CTRP1 5.0266 8.8013 4.5254 22.0798
TOV-112D CTRP2 5.2346 8.5204 4.8435 20.3005
TYK-nu CTRP2; CTRP1 5.4118 7.6231 5.2785 18.196
HEY A8 CTRP2; CTRP1 5.5661 6.9658 5.5419 16.7918
OVKATE CTRP1 5.6356 9.2333 5.0213 38.0283
OV-90 CTRP2; CTRP1 5.6606 7.8073 5.5083 16.6082
OVK18 CTRP2; CTRP1 5.6648 8.2334 5.4001 16.9842
OVCAR-4 CTRP1 5.7082 10.3084 4.6588 38.9251
MCAS CTRP2 5.7794 8.1824 5.54 16.1311
RMUG-S CTRP1 5.8877 8.6171 5.5165 33.5054
FU-OV-1 CTRP2 6.2416 8.9511 5.3493 9.348
SNU-8 CTRP2 6.3753 7.1047 6.3713 11.3382
COV644 CTRP2; CTRP1 6.4883 11.183 5.0603 16.078
OVMANA CTRP1 6.5089 9.186 4.0418 4.6054
OAW28 CTRP2 6.5366 9.1687 6.0094 12.1973
OVISE CTRP2 6.5804 7.0943 6.5796 9.9623
SNU-119 CTRP2 6.5924 8.9352 6.1621 11.4552
JHOS-4 CTRP1 6.6681 8.3655 4.4767 1.2951
JHOM-1 CTRP2; CTRP1 6.7472 11.4847 5.1686 15.0187
Caov-3 CTRP2; CTRP1 6.7498 9.1653 6.2344 10.7468
OC 314 CTRP2 6.7914 9.4179 6.1696 10.8906
DOV13 CTRP2 6.7973 8.3282 6.6045 9.202
RMG-I CTRP2; CTRP1 6.8683 10.759 5.6315 12.8592
IGROV-1 CTRP2; CTRP1 6.8867 9.9236 6.0399 11.1637
COV318 CTRP1 6.9302 8.0392 4.7029 0.1747
ONCO-DG-1 CTRP2 7.237 8.4422 7.0398 6.3045
OVCAR-5 CTRP2 7.266 9.0568 6.8148 7.1031
OVSAHO CTRP2 7.277 8.7836 6.9449 6.561
Kuramochi CTRP2 7.3195 11.3193 5.7881 11.1736
OVTOKO CTRP2 7.3693 10.4247 6.2714 9.0656
OV56 CTRP2 7.4017 10.0782 6.4698 8.1738
JHOS-2 CTRP2 7.4479 10.1857 6.4613 8.1027
EFO-21 CTRP2; CTRP1 7.6349 8.9397 7.2382 4.4778
OV7 CTRP2; CTRP1 7.6697 13.7142 4.9121 14.0063
SNU-840 CTRP2; CTRP1 7.9301 12.0248 5.9793 9.0911
JHOC-5 CTRP2; CTRP1 7.9455 10.5443 6.732 5.9057
COV362 CTRP2; CTRP1 8.2222 15.3974 4.5369 14.3793
OAW42 CTRP2; CTRP1 8.4596 10.3564 7.2382 2.8488
EFO-27 CTRP2; CTRP1 8.9415 15.0318 5.2911 10.0736
SK-OV-3 CTRP2; CTRP1 9.1526 12.1374 6.8579 3.378
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 7.8501 10.1644 6.076 2.8312
SYO-1 CTRP2 10.0678 12.5836 7.1867 1.2337
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 8.6016 11.7182 6.6728 4.9578
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP1 5.3695 8.686 3.4973 12.6714
NCI-H28 CTRP1 5.7677 8.6 3.8387 8.3412
NCI-H2052 CTRP2; CTRP1 6.4521 8.4947 5.7699 6.9619
MPP 89 CTRP2 7.0276 10.232 6.0357 10.8342
NCI-H2452 CTRP2 7.1128 9.9221 6.2649 9.6974
IST-Mes1 CTRP2 7.2929 11.0613 5.8897 10.8138
ACC-MESO-1 CTRP2 7.7948 11.7116 6.0194 9.1963
JL-1 CTRP2 8.5263 10.6167 7.1592 3.0685
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC CTRP2 4.3573 7.7575 4.1001 25.6404
DU145 CTRP2 4.59 7.8836 4.3225 24.1324
NCI-H660 CTRP2 5.2681 8.8396 4.7739 20.4572
22Rv1 CTRP2 6.4583 9.2995 5.8733 12.9372
PaCa-3 CTRP2; CTRP1 7.3986 8.8798 7.0285 5.9126
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 CTRP2 7.0998 9.5867 6.4074 9.1541
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 CTRP2 3.9689 6.7957 3.8674 27.6835
ECC10 CTRP2 4.6333 5.494 4.6332 22.9192
GSS CTRP2 4.7551 6.2251 4.7458 22.1395
SNU-1 CTRP2 4.7672 7.9692 4.4938 22.9772
AGS CTRP2; CTRP1 4.999 7.5709 4.8413 21.0274
HuG1-N CTRP2 5.1545 9.1426 4.5441 21.6359
HGC-27 CTRP2 5.4318 6.9527 5.4021 17.7044
Fu97 CTRP2; CTRP1 5.5654 7.2916 5.3514 11.2468
NUGC-4 CTRP2; CTRP1 5.7915 8.2281 5.5399 16.0951
GSU CTRP2 5.9754 9.3595 5.3396 16.3169
SNU-620 CTRP2 6.0725 7.6242 5.9943 13.6078
OCUM-1 CTRP2 6.3837 8.6137 6.059 12.4355
MKN45 CTRP2 6.4749 7.6148 6.4297 10.8157
MKN74 CTRP2; CTRP1 6.5723 11.5711 4.9589 16.2759
23132/87 CTRP2 6.5919 8.4154 6.3527 10.7363
KE-39 CTRP2 6.6489 9.6931 5.9027 12.3172
MKN7 CTRP2; CTRP1 6.756 10.9881 5.4138 14.01
IM95 CTRP2 6.876 9.4232 6.2542 10.3356
SNU-601 CTRP2 6.934 9.3399 6.3503 9.8047
SNU-216 CTRP2 6.9954 9.9575 6.1324 10.5211
ECC12 CTRP2 7.1451 9.6026 6.4453 8.8886
SNU-719 CTRP2 7.3053 9.9421 6.4429 8.5098
KATO III CTRP2 7.3677 10.022 6.4646 8.2741
Hs 746.T CTRP2 7.3812 8.8698 7.0152 6.0105
SH-10-TC CTRP2; CTRP1 7.4705 9.3517 6.8835 6.3176
MKN1 CTRP2 7.4759 10.0516 6.5528 7.6611
LMSU CTRP2 8.0678 13.1163 5.5495 10.6082
SNU-668 CTRP2 9.0177 16.1795 4.7804 11.9699
NUGC-3 CTRP2 10.0798 11.9875 7.4328 0.5485
SNU-1077 CTRP2 6.4181 8.5685 6.112 12.1378
SNG-M CTRP2; CTRP1 6.9244 9.1024 6.4429 9.4649
SNU-685 CTRP2 8.99 12.5896 6.5288 4.9364
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8505C CTRP2 5.2363 7.5399 5.1052 19.3554
FTC-133 CTRP2 6.5276 10.0314 5.6289 13.7155
8305C CTRP2 7.0057 8.9695 6.5838 8.6971
ML-1 [Human leukemia] CTRP2 7.0554 9.0117 6.6176 8.4323
TT CTRP2 7.3254 8.3649 7.1634 5.5863
SW579 CTRP2 7.3716 9.0773 6.9126 6.4437
B-CPAP CTRP2 7.3933 10.7743 6.1232 9.6236
FTC-238 CTRP2 7.5145 9.8886 6.6682 7.097
TT2609-C02 CTRP2 7.6587 10.9294 6.2886 8.3557
CGTH-W-1 CTRP2 7.6957 10.3528 6.6075 6.9467
BHT-101 CTRP2 9.4071 13.1905 6.5256 4.3505
CAL-62 CTRP2 9.807 11.3323 7.5675 0.3672
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FaDu CTRP2 3.6852 4.1952 3.6852 29.2293
HSC-2 CTRP2; CTRP1 4.433 5.3806 4.4328 24.2528
HSC-4 CTRP2 4.5699 4.9453 4.5699 23.3414
HSC-3 CTRP2 4.6387 5.7483 4.6376 22.887
SNU-1214 CTRP2 5.9184 8.8822 5.461 16.0157
SCC-25 CTRP2 6.3341 8.1842 6.1446 12.2652
SCC-4 CTRP2 7.0163 10.8893 5.712 12.1801
BHY CTRP2 7.1793 9.5089 6.5225 8.4924
YD-8 CTRP2 7.1825 8.8199 6.8311 7.2584
SNU-899 CTRP2 7.2194 11.6606 5.5283 12.4665
SNU-1066 CTRP2 7.3072 9.817 6.5043 8.2546
PE/CA-PJ34 (clone C12) CTRP2 7.4667 8.9771 7.0539 5.6378
CAL-33 CTRP2 7.5878 8.9416 7.191 4.7843
BICR 22 CTRP2 7.6464 8.5978 7.4065 3.7723
BICR 18 CTRP2 7.6747 9.0646 7.2178 4.4659
PE/CA-PJ15 CTRP2 7.7213 12.1573 5.7332 10.5396
CAL-27 CTRP2 7.7247 10.7152 6.4538 7.526
PE/CA-PJ49 CTRP2 7.7804 11.3321 6.1961 8.4873
BICR 16 CTRP2 7.7884 8.8106 7.4486 3.2524
SNU-1041 CTRP2 7.7969 11.2314 6.2606 8.1837
BICR 31 CTRP2 7.8173 11.5954 6.0969 8.8264
BICR 6 CTRP2 7.9193 8.6134 7.6681 2.0465
PE/CA-PJ41 (clone D2) CTRP2 8.0288 9.0999 7.5248 2.4125
SCC-9 CTRP2; CTRP1 8.267 11.7949 6.3738 6.7925
BICR 56 CTRP2 8.2854 9.5304 7.5157 1.9834
SNU-46 CTRP2 8.6319 20.8852 2.1292 21.7216
SNU-1076 CTRP2 9.5218 11.9617 7.1654 1.7792
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KU-19-19 CTRP2 4.5957 5.0025 4.5957 23.1694
UM-UC-3 CTRP2; CTRP1 4.8117 5.8637 4.8107 21.7349
VM-CUB-1 CTRP2 5.1935 7.9065 4.975 19.9494
SCaBER CTRP2 5.3752 7.0246 5.3352 18.1162
J82 CTRP2 5.7777 8.4601 5.4535 16.4525
KMBC-2 CTRP2; CTRP1 6.438 9.4671 5.7821 13.3469
RT-4 CTRP2; CTRP1 6.4434 10.3671 5.3925 14.8697
5637 CTRP2; CTRP1 6.5419 8.4112 6.2998 11.079
TCCSUP CTRP2 6.6901 8.7489 6.3386 10.5085
U-BLC1 CTRP2 6.8978 9.9238 6.0509 11.0918
JMSU-1 CTRP2 7.1991 9.7915 6.4109 8.8951
BFTC-905 CTRP2 7.2004 8.6637 6.9144 6.8864
T24 CTRP2 7.2056 9.61 6.502 8.5103
639V CTRP2 7.4083 8.0083 7.3648 4.6001
HT-1376 CTRP2; CTRP1 7.5108 10.3001 6.4642 7.9485
BC-3C CTRP2 7.5231 10.1848 6.5321 7.6398
SW1710 CTRP2 7.7298 9.0255 7.2894 4.0428
647V CTRP2 8.3349 10.9743 6.8371 4.7292
253J-BV CTRP2 10.1157 11.5004 7.6277 0.1618
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 9.3914 12.7161 6.7399 3.5276

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5244).
2 Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry. 2007 Nov 13;46(45):13019-30.