Details of the Drug

General Information of Drug (ID: DMBWUR0)

• Drug Name: WZ-3146
• Synonyms: WZ-4002; WZ-8040; EGFR-T790M kinase inhibitors (lung cancer); EGFR-T790M kinase inhibitors (lung cancer), Gatekeeper Pharmaceuticals

Indication

Disease Entry	ICD 11	Status	REF
Lung cancer	2C25.0	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 464.9
  Logarithm of the Partition Coefficient (xlogp); 4.3
  Rotatable Bond Count (rotbonds); 7
  Hydrogen Bond Donor Count (hbonddonor); 2
  Hydrogen Bond Acceptor Count (hbondacc); 7
• Chemical Identifiers:
  Formula: C24H25ClN6O2
  IUPAC Name: N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
  Canonical SMILES: CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)OC4=CC=CC(=C4)NC(=O)C=C)Cl
  InChI: InChI=1S/C24H25ClN6O2/c1-3-22(32)27-18-5-4-6-20(15-18)33-23-21(25)16-26-24(29-23)28-17-7-9-19(10-8-17)31-13-11-30(2)12-14-31/h3-10,15-16H,1,11-14H2,2H3,(H,27,32)(H,26,28,29)
  InChIKey: APHGZZPEOCCYNO-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 44607360
  ChEBI ID: CHEBI:94728
  CAS Number: 1214265-56-1
  TTD ID: D0NJ3Q

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Epidermal growth factor receptor (EGFR)	TTGKNB4	EGFR_HUMAN	Inhibitor	[1]

Molecular Expression Atlas of This Drug

• The Studied Disease: Lung cancer
• ICD Disease Classification: 2C25.0

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Epidermal growth factor receptor (EGFR)	DTT	EGFR	5.84E-05	0.32	0.55

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 219 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MEC1	CTRP2	1.1867	3.0759	1.1806	32.3831
JK1	CTRP2	2.326	4.3499	2.2941	24.8795
MEC1	CTRP2	2.8698	5.1175	2.6508	15.2557
JM1	CTRP2	1.4801	2.484	1.4801	30.4081
JM1	CTRP2	2.2483	4.7864	2.0593	19.2834
Ri-1	CTRP2	-2.507	5.5073	-3.147	55.3765
HH [Human lymphoma]	CTRP2	-0.3836	3.0803	-0.4361	42.9553
SK-MM-2	CTRP2	-0.0884	21.5889	-7.8164	44.2865
Mino	CTRP2	0.0531	3.5787	-0.0218	40.1284
Pfeiffer	CTRP2	0.1514	3.5186	0.0873	39.4492
MJ	CTRP2	0.4114	4.3899	0.2568	37.986
EoL-1	CTRP2	0.4786	2.2905	0.4767	37.0865
SET-2	CTRP2	0.5406	2.1467	0.5398	36.6698
SUP-B15	CTRP2	0.7162	3.0035	0.7038	35.5382
Mono-Mac-1	CTRP2	0.7557	3.3162	0.731	35.3148
Pfeiffer	CTRP2	0.7751	2.1774	0.7735	28.4479
L-540	CTRP2	0.8529	3.358	0.7966	28.1133
Ri-1	CTRP2	0.8901	3.7665	0.7848	28.0322
HL-60	CTRP2	0.9085	2.8738	0.9027	34.2353
DB	CTRP2	0.927	3.5415	0.8952	34.1975
EoL-1	CTRP2	0.9758	2.2248	0.9749	27.1087
Granta-519	CTRP2	0.9815	3.5065	0.9538	33.8212
TF-1	CTRP2	0.9914	3.5028	0.9642	33.7537
Daudi	CTRP2	1.0054	2.5296	1.0044	33.5737
Mono-Mac-1	CTRP2	1.0701	3.0376	1.0492	26.547
Ci-1	CTRP2	1.1099	2.4277	1.1096	32.8753
ALL-SIL	CTRP2	1.1118	2.1706	1.1117	32.862
697	CTRP2	1.2115	2.0204	1.2114	25.5356
AML-193	CTRP2	1.2133	2.4911	1.2131	32.1861
NALM-6	CTRP2	1.223	3.321	1.2108	32.1615
JeKo-1	CTRP2	1.2308	4.136	1.1632	32.2929
SEM	CTRP2	1.2912	2.8133	1.2898	31.6712
MOLP-2	CTRP2	1.3098	3.099	1.305	31.5586
CMK	CTRP2	1.3101	2.4348	1.31	31.5409
SUP-M2	CTRP2	1.3143	2.1775	1.3143	31.5125
697	CTRP2	1.3232	2.3582	1.3231	31.4536
OPM-2	CTRP2	1.3334	2.1197	1.3334	24.723
Namalwa	CTRP2	1.3338	3.2452	1.326	31.4087
U-937	CTRP2	1.3384	3.4325	1.3248	31.3973
Hs 611.T	CTRP2	1.3488	2.4712	1.3487	31.2829
Kasumi-1	CTRP2	1.3565	2.4698	1.3564	31.2315
EB1	CTRP2	1.3656	2.9237	1.3637	31.1772
OCI-AML-3	CTRP2	1.3879	2.3537	1.3879	31.0225
SEM	CTRP2	1.4024	2.0626	1.4024	24.2637
OPM-2	CTRP2	1.4074	2.1686	1.4074	30.8922
Hs 611.T	CTRP2	1.4294	2.2909	1.4293	24.0839
RS4;11	CTRP2	1.4372	2.7757	1.4365	30.6962
Daudi	CTRP2	1.4386	2.2953	1.4385	24.0225
GA-10	CTRP2	1.4416	2.1067	1.4415	24.0027
MOLT-3	CTRP2	1.4423	1.9123	1.4423	30.6598
Kasumi-2	CTRP2	1.447	3.3434	1.4207	24.0548
SET-2	CTRP2	1.4636	2.1982	1.4636	23.8556
SIG-M5	CTRP2	1.4749	3.1076	1.4718	30.4529
OCI-Ly19	CTRP2	1.478	5.8551	0.9042	25.7658
RL	CTRP2	1.4949	3.0224	1.4929	30.3164
ST486	CTRP2	1.4952	2.3376	1.4951	23.6457
KO52	CTRP2	1.4969	2.2225	1.4969	30.2961
Kasumi-2	CTRP2	1.5016	2.3184	1.5016	30.2646
AML-193	CTRP2	1.5059	2.067	1.5059	23.5737
OCI-Ly19	CTRP2	1.5127	3.4235	1.5033	30.2221
RS4;11	CTRP2	1.513	3.2328	1.496	23.5839
HuT 78	CTRP2	1.5141	3.2016	1.4988	23.5705
RCH-ACV	CTRP2	1.5256	3.6581	1.5073	30.1658
MOLM-16	CTRP2	1.5258	2.4893	1.5255	23.4422
DND-41	CTRP2	1.5292	3.0505	1.5206	23.4474
SUP-M2	CTRP2	1.5308	2.0931	1.5308	23.4084
A4/Fukuda	CTRP2	1.5311	3.2057	1.527	30.082
OCI-AML-3	CTRP2	1.5341	1.9866	1.5341	23.3863
CA46	CTRP2	1.537	2.8659	1.5363	30.0315
MOLT-16	CTRP2	1.5956	3.1237	1.5859	23.0091
LP-1	CTRP2	1.6063	2.3032	1.6063	22.9054
EB1	CTRP2	1.619	3.0826	1.6113	22.8461
SUP-HD1	CTRP2	1.6246	3.1256	1.6225	29.4521
KMS-20	CTRP2	1.6533	3.1174	1.6451	22.6192
KO52	CTRP2	1.6698	3.381	1.6496	22.55
L-540	CTRP2	1.6917	3.2643	1.6885	29.009
KE-97	CTRP2	1.7034	2.5852	1.7034	28.9204
KMS-34	CTRP2	1.7083	2.8299	1.7068	22.2304
MOTN-1	CTRP2	1.7085	2.8376	1.7083	28.8869
MOLT-3	CTRP2	1.7095	2.571	1.7094	22.2178
SUP-T11	CTRP2	1.7176	2.9103	1.7173	28.8268
Kasumi-1	CTRP2	1.7243	2.7722	1.7234	22.1216
HuNS1	CTRP2	1.7657	3.3394	1.7621	28.5174
TALL-1 [Human adult T-ALL]	CTRP2	1.7705	2.9609	1.7701	28.4745
L-428	CTRP2	1.7783	3.419	1.7597	21.8214
KHM-1B	CTRP2	1.7806	2.4389	1.7806	28.4063
EHEB	CTRP2	1.7815	3.0461	1.7808	28.4025
LP-1	CTRP2	1.7831	2.5812	1.783	28.3897
MOLT-13	CTRP2	1.7944	3.4247	1.7761	21.7131
A3/Kawakami	CTRP2	1.7945	2.6159	1.7945	28.3132
MOLP-8	CTRP2	1.7951	2.8476	1.795	28.3099
ST486	CTRP2	1.7972	2.6314	1.7972	28.2956
KM-H2	CTRP2	1.8037	2.9372	1.8034	28.2531
Karpas-422	CTRP2	1.8109	4.0256	1.7811	28.3042
TALL-1 [Human adult T-ALL]	CTRP2	1.8286	3.3814	1.8138	21.4735
RPMI-6666	CTRP2	1.8325	3.1112	1.8317	28.0627
KMS-34	CTRP2	1.8483	2.6422	1.8483	27.9551
HuT 78	CTRP2	1.8568	3.2706	1.8549	27.905
JVM-3	CTRP2	1.8685	2.6536	1.8684	27.8207
MOTN-1	CTRP2	1.8848	5.3738	1.5009	22.3994
M-07e	CTRP2	1.8878	3.1569	1.883	21.0457
Ku812	CTRP2	1.8984	2.9893	1.8982	27.6219
Jurkat	CTRP2	1.9028	2.7636	1.9028	27.5922
WSU-DLCL2	CTRP2	1.9067	2.6058	1.9067	27.5662
BL-70	CTRP2	1.9165	2.8531	1.9165	27.5006
DB	CTRP2	1.9222	3.4961	1.9042	20.8609
SKM-1	CTRP2	1.9346	3.4279	1.9207	20.7644
NU-DUL-1	CTRP2	1.9349	3.4486	1.9199	20.7662
MOLM-6	CTRP2	1.9525	3.472	1.9488	27.2731
M-07e	CTRP2	1.9839	2.8144	1.9839	27.0515
OCI-Ly3	CTRP2	2.003	3.6918	1.995	26.9509
MM1.S	CTRP2	2.025	3.1769	2.0245	26.7795
HDLM-2	CTRP2	2.0324	3.1699	2.0319	26.73
KMS-12-BM	CTRP2	2.0346	2.8888	2.0346	26.7138
DND-41	CTRP2	2.044	3.0893	2.0438	26.652
EJM	CTRP2	2.0454	2.9921	2.0453	26.6423
SK-MM-2	CTRP2	2.0467	3.1975	2.0462	26.6349
SUP-HD1	CTRP2	2.0517	5.7092	1.5753	21.6297
BL-70	CTRP2	2.0648	3.3175	2.0587	19.8707
A3/Kawakami	CTRP2	2.0855	3.6743	2.0617	19.7927
RCH-ACV	CTRP2	2.0894	4.4191	1.9662	20.109
SUP-T1	CTRP2	2.0969	3.539	2.0824	19.6852
SU-DHL-6	CTRP2	2.0984	3.9486	2.049	19.7935
SU-DHL-6	CTRP2	2.0996	4.6583	2.0234	26.5381
PL21	CTRP2	2.1037	3.3857	2.0962	19.6166
HEL 92.1.7	CTRP2	2.1204	3.982	2.1041	26.1966
KMS-20	CTRP2	2.1233	2.887	2.1233	26.123
LAMA-84	CTRP2	2.1341	3.3067	2.1334	26.0535
MOLM-16	CTRP2	2.1468	3.2147	2.1465	25.9672
K-562	CTRP2	2.1652	4.0711	2.1457	25.909
KMS-18	CTRP2	2.1728	3.3136	2.1722	25.7951
MM1.S	CTRP2	2.191	4.2174	2.111	19.2818
THP-1	CTRP2	2.1923	3.433	2.191	25.6675
NU-DUL-1	CTRP2	2.1998	3.6181	2.1964	25.6246
Karpas-299	CTRP2	2.2235	3.6452	2.2071	18.8482
THP-1	CTRP2	2.2453	4.4074	2.1371	19.0183
HEL	CTRP2	2.2662	3.0314	2.2662	25.1709
U-937	CTRP2	2.2715	3.8057	2.2456	18.5604
L-428	CTRP2	2.2949	3.1224	2.2949	24.9797
KMS-11	CTRP2	2.296	3.9126	2.2617	18.4259
MOLT-16	CTRP2	2.3066	3.095	2.3066	24.9016
F-36P	CTRP2	2.3319	3.0805	2.3319	24.7335
MOLM-6	CTRP2	2.3429	3.9069	2.3116	18.1029
REC-1	CTRP2	2.3522	5.204	2.2094	25.085
Granta-519	CTRP2	2.3551	5.8673	1.8498	19.7275
KCL-22	CTRP2	2.3793	3.4766	2.3787	24.4192
GDM-1	CTRP2	2.3839	4.1832	2.3227	17.9325
HD-MY-Z	CTRP2	2.3882	2.9634	2.3882	24.3581
OCI-M1	CTRP2	2.4279	2.9449	2.4279	24.0937
HPB-ALL	CTRP2	2.4297	3.0148	2.4297	24.0817
MHH-CALL-4	CTRP2	2.4638	3.3298	2.4637	23.8546
DEL	CTRP2	2.4913	2.8537	2.4913	23.671
U266B1	CTRP2	2.4936	3.0919	2.4936	23.6559
OCI-AML-2	CTRP2	2.5033	4.2437	2.4417	17.1386
Reh	CTRP2	2.5134	4.1334	2.4673	17.0179
MC116	CTRP2	2.5403	5.5583	2.3412	24.0299
ME1	CTRP2	2.5469	4.3035	2.4795	16.8682
CA46	CTRP2	2.5486	4.2218	2.4932	16.8152
OCI-AML-5	CTRP2	2.5547	2.9038	2.5547	23.2486
MOLP-8	CTRP2	2.5614	4.4238	2.4753	16.8361
SU-DHL-4	CTRP2	2.5629	4.2846	2.5447	23.2552
JeKo-1	CTRP2	2.5742	4.5105	2.4733	16.8025
NU-DHL-1	CTRP2	2.5746	3.1365	2.5746	23.1164
JJN-3	CTRP2	2.5798	3.0631	2.5798	23.0815
SU-DHL-10	CTRP2	2.5828	12.5659	-0.4131	32.3633
SU-DHL-8	CTRP2	2.6402	4.873	2.5712	22.9128
Namalwa	CTRP2	2.6565	4.4997	2.5644	16.2235
KMS-12-BM	CTRP2	2.6597	4.5922	2.55	16.264
OCI-Ly10	CTRP2	2.7046	6.3683	2.3062	23.6462
AMO1	CTRP2	2.7335	3.85	2.732	22.0625
KYO-1	CTRP2	2.7564	4.0659	2.7516	21.921
SUP-T11	CTRP2	2.8731	4.8842	2.7165	15.0095
CMK	CTRP2	2.917	4.4633	2.8516	14.396
L-1236	CTRP2	3.0161	5.1664	2.9313	43.7138
MHH-CALL-4	CTRP2	3.0269	4.6935	2.9276	13.7824
MHH-CALL-3	CTRP2	3.06	5.3919	2.9396	20.2948
NOMO-1	CTRP2	3.1643	4.6626	3.0828	12.805
HL-60	CTRP2	3.2327	5.3569	2.9738	12.9899
Mono-Mac-6	CTRP2	3.2722	8.2936	1.7802	17.5272
HPB-ALL	CTRP2	3.2731	4.534	3.223	11.9711
SUP-B15	CTRP2	3.2815	6.2202	2.7081	13.8572
RPMI-8226	CTRP2	3.3071	4.5078	3.2634	11.7228
BV-173	CTRP2	3.3306	4.8212	3.23	11.7649
KMS-18	CTRP2	3.3371	4.7159	3.2595	11.6405
NB4	CTRP2	3.3412	4.3438	3.3199	11.4189
F-36P	CTRP2	3.3533	4.9357	3.2274	11.704
HD-MY-Z	CTRP2	3.3785	5.0159	3.234	11.6029
Karpas-422	CTRP2	3.3867	6.4552	2.7213	13.5211
NU-DHL-1	CTRP2	3.4112	4.5612	3.367	11.031
RPMI-6666	CTRP2	3.4815	6.0508	2.9876	12.2297
Raji	CTRP2	3.5159	4.0417	3.5151	10.1859
TF-1	CTRP2	3.5463	5.9522	3.0957	11.6347
SU-DHL-8	CTRP2	3.561	4.9832	3.4419	10.2975
SR	CTRP2	3.5985	4.2444	3.5942	9.6471
L-363	CTRP2	3.6251	4.2232	3.6221	9.4655
MHH-CALL-3	CTRP2	3.7054	6.064	3.2181	10.7263
U266B1	CTRP2	3.7117	5.4571	3.4595	9.785
OCI-Ly3	CTRP2	3.7434	16.7917	-1.9458	28.2441
SU-DHL-4	CTRP2	3.7605	4.3539	3.7559	8.5689
MC116	CTRP2	3.7873	5.3248	3.5868	9.0904
JJN-3	CTRP2	3.79	5.2062	3.6281	8.9302
MOLP-2	CTRP2	3.7969	5.0501	3.6814	8.7152
K-562	CTRP2	3.8109	5.8324	3.4237	9.6425
OCI-AML-5	CTRP2	3.9625	4.5988	3.949	7.253
HEL 92.1.7	CTRP2	4.126	6.9376	3.2547	9.5056
Karpas-620	CTRP2	4.1631	5.397	4.125	12.6626
EJM	CTRP2	4.5027	18.1628	-1.9716	26.6972
Karpas-620	CTRP2	4.5723	5.3222	4.4336	3.6539
KYO-1	CTRP2	4.7438	7.7459	3.4356	7.3655
KMM-1	CTRP2	5.0553	9.6695	3.3535	13.3591
AMO1	CTRP2	5.2459	6.8159	4.3205	2.6756
P3HR-1	CTRP2	5.3359	12.2792	2.3185	16.8579
REC-1	CTRP2	5.9509	10.5208	3.02	6.9049
RL	CTRP2	5.965	9.9333	3.3182	5.6585
P3HR-1	CTRP2	6.1236	8.2005	4.2492	1.7447
Ci-1	CTRP2	6.3434	7.4201	4.6877	0.2227
SIG-M5	CTRP2	6.3655	7.3899	4.7077	0.1774
OCI-Ly10	CTRP2	6.4175	17.0702	0.134	17.0551
OCI-M1	CTRP2	6.4457	7.9702	4.5189	0.576

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Oesophagus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
TE15	CTRP2	0.3761	4.114	0.2587	38.1142
TE8	CTRP2	1.6789	3.6964	1.6633	29.1357
TE8	CTRP2	2.0407	5.2022	1.722	21.1291
OE21	CTRP2	0.3718	3.1941	0.3412	37.8882
OE21	CTRP2	0.7506	2.8233	0.7309	28.6719
TE-4	CTRP2	1.2044	4.0341	1.1457	32.4395
KYSE-140	CTRP2	1.293	4.275	1.2135	31.9187
TE-14	CTRP2	1.37	4.9562	1.1937	31.7255
OE33	CTRP2	1.7634	5.7338	1.2543	23.6552
EC-GI-10	CTRP2	1.8107	4.7884	1.6965	28.5907
TE-14	CTRP2	1.8365	9.2861	-0.1117	28.0962
OE33	CTRP2	1.8861	3.0501	1.8857	27.7046
TE-6	CTRP2	1.8951	4.0824	1.8648	27.7449
OE19	CTRP2	1.9154	4.985	1.7771	27.9763
TE-11	CTRP2	1.9234	3.0759	1.923	27.4561
TE-5	CTRP2	2.028	3.103	2.0278	26.7584
EC-GI-10	CTRP2	2.203	5.2625	1.8813	20.0615
TE-5	CTRP2	2.2043	4.4193	2.0904	19.3112
KYSE-450	CTRP2	2.2241	4.2905	2.1922	25.5584
TE-1	CTRP2	2.2591	4.9823	2.1474	25.5978
TE-11	CTRP2	2.2633	4.8527	2.0594	19.2365
TE-10	CTRP2	2.2891	4.1994	2.2662	25.095
KYSE-30	CTRP2	2.3126	2.8666	2.3126	24.8615
COLO 680N	CTRP2	2.3773	3.9646	2.3683	24.4608
KYSE-150	CTRP2	2.4153	3.0494	2.4153	24.1775
KYSE-520	CTRP2	2.442	5.149	2.1751	18.2741
TE-6	CTRP2	2.4535	4.5097	2.3428	17.6405
TE-9	CTRP2	2.4899	3.7839	2.4871	23.6899
KYSE-410	CTRP2	2.579	4.4775	2.4847	16.7474
KYSE-520	CTRP2	2.796	6.1417	2.4723	22.7725
TE-1	CTRP2	2.8639	4.5003	2.7882	14.7854
KYSE-510	CTRP2	2.8817	4.2011	2.8755	21.0909
KYSE-70	CTRP2	2.9223	4.6555	2.8219	14.4827
KYSE-180	CTRP2	3.0447	7.8691	2.1397	23.2461
KYSE-150	CTRP2	3.5483	5.521	3.2605	11.0025
OE19	CTRP2	4.0102	7.9886	2.6414	12.2861
KYSE-510	CTRP2	4.3456	8.4466	2.7308	11.1577
KYSE-70	CTRP2	4.3846	7.6822	3.1421	10.0351
KYSE-30	CTRP2	4.5102	8.9437	2.6334	11.2043
KYSE-450	CTRP2	4.5443	7.389	3.433	7.8045

Cancer Drug Sensitivity Data Curated from 67 Cell Line(s) in Pancreas Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
N2a-PK1	CTRP2	2.2803	3.375	2.2797	25.0789
N2a-PK1	CTRP2	4.4804	7.8794	3.1332	9.1916
HuP-T4	CTRP2	1.3148	3.1325	1.2968	24.9075
HuP-T4	CTRP2	1.4861	3.5358	1.4721	30.4145
BxPC-3	CTRP2	1.9153	3.4801	1.911	27.523
DAN-G	CTRP2	1.9696	2.85	1.9696	27.1468
HPAC	CTRP2	2.0957	3.5669	2.0795	19.6988
Panc 05.04	CTRP2	2.0973	4.4303	1.9726	20.0614
MIA PaCa-2	CTRP2	2.1413	3.1859	2.1411	26.0036
HPAC	CTRP2	2.1435	4.285	2.1086	26.1056
SNU-213	CTRP2	2.2279	5.5857	1.995	26.2247
Hs 766T	CTRP2	2.3094	4.8532	2.2209	25.1829
SW1990	CTRP2	2.3257	4.048	2.3121	24.82
Panc 10.05	CTRP2	2.3661	3.2393	2.366	24.5055
PaTu 8988s	CTRP2	2.3698	3.0452	2.3698	24.481
KP-2	CTRP2	2.3901	2.8312	2.3901	24.3456
KP-3	CTRP2	2.4108	3.5548	2.4098	24.2111
AsPC-1	CTRP2	2.4238	3.973	2.4156	24.1484
Capan-2	CTRP2	2.4286	3.4233	2.4283	24.0899
Panc 08.13	CTRP2	2.5568	3.2721	2.5568	23.235
HuP-T3	CTRP2	2.5582	3.1189	2.5582	23.2255
SU.86.86	CTRP2	2.5819	4.0393	2.5748	23.0914
PaTu 8988t	CTRP2	2.5832	2.9222	2.5832	23.059
PK-59	CTRP2	2.6855	5.1603	2.5768	22.7481
HPAF-II	CTRP2	2.7186	15.7973	-1.8207	34.8821
PK-45H	CTRP2	2.7422	5.4015	2.5936	22.5096
Panc 03.27	CTRP2	2.7527	3.6199	2.7526	21.93
Hs 766T	CTRP2	2.802	5.8559	2.3359	16.6206
Capan-1	CTRP2	2.8173	4.6121	2.7864	21.6031
KP-4	CTRP2	2.8177	3.6656	2.8175	21.4975
Panc 10.05	CTRP2	2.8433	5.8136	2.3956	16.2777
SNU-410	CTRP2	2.9526	4.2744	2.9456	20.6215
Panc 08.13	CTRP2	3.0511	5.9624	2.564	15.0502
L3.3	CTRP2	3.0777	5.3246	2.971	20.1292
PaTu 8988s	CTRP2	3.0941	5.3558	2.8235	13.9535
Panc 05.04	CTRP2	3.231	7.2361	2.2218	17.0211
MIA PaCa-2	CTRP2	3.2951	4.8567	3.1831	12.0417
PK-59	CTRP2	3.2954	4.8525	3.1844	12.0363
QGP-1	CTRP2	3.3895	5.5255	3.2704	18.096
Capan-2	CTRP2	3.4088	5.2414	3.202	11.6282
PaTu 8902	CTRP2	3.5703	4.5392	3.5671	16.4933
PK-45H	CTRP2	3.5861	8.3036	2.0829	15.5561
SU.86.86	CTRP2	3.6448	4.4363	3.6302	9.3734
Panc 02.03	CTRP2	3.711	5.0242	3.6873	15.6252
PANC-1	CTRP2	3.9381	8.8144	2.1733	14.36
Panc 04.03	CTRP2	3.947	5.4463	3.8866	14.179
HuP-T3	CTRP2	3.9513	7.6346	2.7546	11.9625
PSN1	CTRP2	3.9538	4.8944	3.9473	13.9496
SW1990	CTRP2	4.0608	6.4926	3.3966	9.0926
CFPAC-1	CTRP2	4.0953	5.4822	4.0402	13.1729
PSN1	CTRP2	4.1768	7.2359	3.1622	9.762
DAN-G	CTRP2	4.2142	5.5159	3.977	6.3996
PaTu 8902	CTRP2	4.2732	4.9095	4.2354	5.2677
Capan-1	CTRP2	4.3202	11.6295	1.1305	17.6044
AsPC-1	CTRP2	4.4271	7.7404	3.1527	9.2282
L3.3	CTRP2	4.5875	7.8986	3.2207	8.5952
KP-2	CTRP2	4.7311	7.7356	3.4296	7.4173
TCC-Pan2	CTRP2	4.9514	8.1222	3.4273	7.4763
Panc 03.27	CTRP2	5.2121	9.2837	3.0628	8.0076
SUIT-2	CTRP2	5.2706	8.2385	4.2506	9.1794
YAPC	CTRP2	5.3329	7.3045	4.1449	3.4921
SNU-410	CTRP2	5.9279	9.2192	3.6395	4.4021
TCC-Pan2	CTRP2	6.2389	8.8112	4.0389	2.401
YAPC	CTRP2	6.3052	8.2416	4.334	1.259
Panc 04.03	CTRP2	6.6814	9.9794	3.7709	2.8965
Panc 02.03	CTRP2	6.7345	10.4694	3.5776	3.5644
PaTu 8988t	CTRP2	6.738	8.9107	4.2736	1.0924

Cancer Drug Sensitivity Data Curated from 91 Cell Line(s) in Skin Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SH4	CTRP2	1.554	2.834	1.551	23.2635
SK-MEL-3	CTRP2	1.3943	4.5017	1.1949	25.0021
Hs 934.T	CTRP2	1.5243	6.6133	0.6838	26.3961
COLO 792	CTRP2	1.5777	2.1641	1.5777	23.0957
Hs 852.T	CTRP2	1.7259	4.1222	1.6265	22.4467
HT-144	CTRP2	1.941	3.3414	1.9313	20.7077
SK-MEL-24	CTRP2	1.9764	3.1607	1.9728	20.4517
WM115	CTRP2	1.9864	3.0302	1.9848	20.3782
Hs 934.T	CTRP2	2.03	3.6165	2.0244	26.7632
Hs 688(A).T	CTRP2	2.0832	4.7191	1.8954	20.3774
G-361	CTRP2	2.1311	3.4869	2.1203	19.4449
HMCB	CTRP2	2.1775	2.7208	2.1775	25.7618
Hs 294T	CTRP2	2.1822	3.2629	2.1818	25.7317
MeWo	CTRP2	2.1892	2.8926	2.1892	25.6839
Hs 688(A).T	CTRP2	2.1893	3.1279	2.1892	25.6835
Hs 839.T	CTRP2	2.2154	2.9449	2.2154	25.5091
Hs 940.T	CTRP2	2.227	3.341	2.2265	25.4336
RPMI-7951	CTRP2	2.2824	3.05	2.2824	25.0627
WT2-iPS	CTRP2	2.2883	2.941	2.2883	25.0237
COLO 792	CTRP2	2.3033	3.0188	2.3033	24.9237
G-361	CTRP2	2.3201	3.947	2.2837	19.5765
WM1799	CTRP2	2.351	2.9242	2.351	24.6059
HT-144	CTRP2	2.3699	2.9009	2.3699	24.4799
Hs 944.T	CTRP2	2.4214	3.4753	2.4209	24.1384
UACC-257	CTRP2	2.457	2.8983	2.457	23.8996
IGR-39	CTRP2	2.4618	2.874	2.4618	23.8677
CJM [Human melanoma]	CTRP2	2.4686	2.8901	2.4686	23.8226
SK-MEL-24	CTRP2	2.4703	2.9279	2.4703	23.8109
UACC-62	CTRP2	2.4713	2.8608	2.4713	23.8045
A101D	CTRP2	2.4726	2.903	2.4726	23.7959
Hs 944.T	CTRP2	2.4784	3.9842	2.4467	17.202
COLO 829	CTRP2	2.4981	4.1656	2.484	23.6732
Mel Ho	CTRP2	2.5002	2.9324	2.5002	23.6116
IGR-1	CTRP2	2.5234	2.9799	2.5234	23.4575
SK-MEL-3	CTRP2	2.5293	2.916	2.5293	23.4181
WM266-4	CTRP2	2.5364	2.8628	2.5364	23.3711
MDA-MB-435S	CTRP2	2.5425	4.5123	2.5071	23.449
SK-MEL-1	CTRP2	2.5509	3.0012	2.5509	23.2741
LOX-IMVI	CTRP2	2.5632	3.1497	2.5632	23.1922
WM115	CTRP2	2.5671	2.9175	2.5671	23.1663
A-375	CTRP2	2.5699	4.292	2.5515	23.2095
A2058	CTRP2	2.5827	2.9051	2.5827	23.0626
RVH-421	CTRP2	2.5838	2.9764	2.5838	23.0548
WM88	CTRP2	2.5881	3.076	2.5881	23.0265
Hs 852.T	CTRP2	2.5883	4.8805	2.515	23.2733
MeWo	CTRP2	2.6515	4.2385	2.6008	16.1138
WM793	CTRP2	2.7561	4.7794	2.7057	22.0772
IGR-37	CTRP2	2.808	3.407	2.808	21.5614
SK-MEL-28	CTRP2	2.8484	3.4467	2.8484	21.292
K029AX	CTRP2	2.8497	4.21	2.8426	21.3073
IGR-1	CTRP2	2.8861	4.5376	2.8055	14.6545
Hs 895.T	CTRP2	2.8958	4.5361	2.8741	21.049
Hs 294T	CTRP2	2.9072	4.279	2.8677	14.3719
IPC-298	CTRP2	2.9522	3.6031	2.9522	20.6006
A101D	CTRP2	3.0505	4.496	2.9899	13.4902
COLO 800	CTRP2	3.0542	4.5079	3.04	19.9688
WM266-4	CTRP2	3.1207	4.2007	3.1014	12.8808
A-375	CTRP2	3.1738	5.2835	2.933	13.3145
SK-MEL-28	CTRP2	3.1794	4.2933	3.1544	12.5092
SK-MEL-5	CTRP2	3.2639	3.9011	3.2639	18.5242
WM1799	CTRP2	3.2662	7.1915	2.2776	15.5825
WT2-iPS	CTRP2	3.2955	4.9865	3.1513	12.1543
COLO 800	CTRP2	3.3041	5.6446	2.9531	12.8592
WM793	CTRP2	3.4296	7.4791	2.313	15.0237
WM88	CTRP2	3.4491	4.9172	3.3364	11.0191
MDA-MB-435S	CTRP2	3.4838	8.4643	1.9074	16.5032
IPC-298	CTRP2	3.4988	6.5566	2.7945	12.9361
WM983B	CTRP2	3.5192	4.7127	3.5089	16.8578
RVH-421	CTRP2	3.5619	4.9621	3.4482	10.272
SK-MEL-31	CTRP2	3.5822	4.6325	3.5767	16.4221
Mel JuSo	CTRP2	3.585	4.028	3.5847	9.7238
SK-MEL-5	CTRP2	3.6283	5.47	3.3649	10.3802
UACC-257	CTRP2	3.6863	5.0572	3.5588	9.4942
A2058	CTRP2	3.8054	4.6476	3.7763	8.3532
SK-MEL-30	CTRP2	3.8072	4.6875	3.8042	14.9144
LOX-IMVI	CTRP2	3.9757	6.1789	3.4502	9.0972
HMCB	CTRP2	4.0291	6.5774	3.3261	9.4554
IGR-37	CTRP2	4.0457	4.857	3.9993	6.8128
K029AX	CTRP2	4.1138	6.4948	3.4487	8.7498
UACC-62	CTRP2	4.2162	4.8446	4.1862	5.62
WM983B	CTRP2	4.2684	8.4288	2.6688	11.5849
IGR-39	CTRP2	4.3117	7.2198	3.2987	8.8862
COLO 829	CTRP2	4.361	6.0159	3.9152	6.2544
Hs 895.T	CTRP2	4.5002	8.3288	2.9292	9.9974
Hs 936.T	CTRP2	4.7291	18.2841	-1.2034	28.8646
SK-MEL-31	CTRP2	6.1497	9.0263	3.882	3.119
SK-MEL-2	CTRP2	6.3812	7.606	4.6332	0.323
Hs 936.T	CTRP2	6.5452	7.8928	4.5933	0.3391
SK-MEL-30	CTRP2	6.5694	8.3903	4.4067	0.8136
Hs 839.T	CTRP2	6.7057	8.9411	4.2444	1.2094
CJM [Human melanoma]	CTRP2	6.7078	7.7308	4.7152	0.0859

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
COLO 684	CTRP2	2.9632	4.8554	2.8219	14.3552

Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Autonomic Ganglia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MHH-NB-11	CTRP2	-0.4347	3.3512	-3.4638	8.3721
CHP-212	CTRP2	0.4832	2.1572	0.4822	37.0529
SK-N-FI	CTRP2	0.9402	2.5291	0.9352	27.3594
SK-N-SH	CTRP2	1.4528	2.2133	1.4527	23.9281
IMR-32	CTRP2	1.4584	2.5289	1.4577	23.8928
CHP-212	CTRP2	1.4936	2.1825	1.4936	23.6562
IMR-32	CTRP2	1.5077	2.0304	1.5077	30.224
NH-6	CTRP2	1.5149	2.6054	1.5141	23.5166
SK-N-BE(2)	CTRP2	1.5538	2.6025	1.5532	23.2567
SK-N-BE(2)	CTRP2	1.7106	3.3608	1.7059	28.8879
SiMa	CTRP2	1.729	3.0239	1.7283	28.7521
SK-N-FI	CTRP2	1.7459	3.5755	1.7364	28.6687
SK-N-SH	CTRP2	1.7922	3.0974	1.7913	28.3317
NH-6	CTRP2	1.8395	2.7327	1.8395	28.0137
SK-N-AS	CTRP2	2.0728	2.8398	2.0728	26.459
KP-N-YN	CTRP2	2.2728	3.4419	2.272	25.1296
SK-N-AS	CTRP2	2.7342	4.831	2.5781	15.9319
Kelly	CTRP2	3.0603	4.3011	3.0276	13.3288
KP-N-SI9s	CTRP2	3.2716	4.2609	3.2544	11.8684
NB1	CTRP2	3.3803	3.9647	3.3792	11.0901
KP-N-YN	CTRP2	4.3265	7.398	3.2264	9.1497

Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SNU-1079	CTRP2	-0.9671	2.8798	-1.0298	46.802
SNU-308	CTRP2	0.7818	4.4386	0.6466	35.4881
SNU-478	CTRP2	1.1789	3.8042	1.1388	32.5478
HuCC-T1	CTRP2	2.4499	5.2344	2.3093	24.4274
SNU-869	CTRP2	2.6923	4.7495	2.6415	22.5034
SNU-1196	CTRP2	2.8325	7.2549	2.1474	23.8355
SNU-869	CTRP2	4.1737	7.3226	3.1177	9.9519

Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Bone Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SK-N-MC	CTRP2	1.6006	1.9249	1.6006	29.605
SK-ES-1	CTRP2	1.6242	3.1331	1.6148	22.8172
SaOS-2	CTRP2	1.6916	3.076	1.6854	22.3575
SK-N-MC	CTRP2	1.7053	2.1483	1.7053	22.2458
MHH-ES-1	CTRP2	2.0075	3.0365	2.0073	26.8949
Hs 888.T	CTRP2	2.1063	3.2519	2.1057	26.2382
A-673	CTRP2	2.1368	3.1586	2.1365	26.034
CAL-78	CTRP2	2.2002	5.6674	1.7504	20.5484
SaOS-2	CTRP2	2.219	3.0333	2.219	25.4854
SK-ES-1	CTRP2	2.2252	2.9718	2.2252	25.4439
TC71	CTRP2	2.3643	3.0042	2.3643	24.5174
Hs 822.T	CTRP2	2.3705	2.8453	2.3705	24.4761
SW1353	CTRP2	2.3978	3.5836	2.3965	24.2985
G-292 clone A141B1	CTRP2	2.4322	3.2516	2.4322	24.0648
MG-63	CTRP2	2.4565	2.9285	2.4565	23.903
HOS	CTRP2	2.5169	2.9359	2.5169	23.5005
Hs 888.T	CTRP2	2.844	6.1493	2.2714	16.745
A-673	CTRP2	2.8475	4.636	2.7448	14.989
TC71	CTRP2	2.9462	4.9575	2.7777	14.5657
SJSA-1	CTRP2	3.2389	4.3612	3.2347	18.7044
Hs 822.T	CTRP2	3.3982	5.8396	2.9818	12.4834
G-292 clone A141B1	CTRP2	3.4566	5.0476	3.3108	11.0883
MG-63	CTRP2	3.5063	4.7118	3.4435	10.4621
SJSA-1	CTRP2	3.5369	4.1676	3.5339	10.0534
HOS	CTRP2	5.0474	7.9019	3.6182	5.9889

Cancer Drug Sensitivity Data Curated from 119 Cell Line(s) in Breast Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HCC2218	CTRP2	-1.7665	2.1378	-1.8098	51.9784
HCC2218	CTRP2	-1.5454	3.7657	-1.8429	44.4367
AU565	CTRP2	-0.3323	3.8407	-0.5439	36.4658
UACC-812	CTRP2	-0.2998	3.8823	-0.431	42.5775
BT-474	CTRP2	0.08	6.4493	-0.5796	41.2237
Hs 578Bst	CTRP2	0.378	7.0396	-4.6788	14.5505
CAL-85-1	CTRP2	0.5521	2.5227	0.5482	36.6031
ZR-75-30	CTRP2	0.7497	4.3734	0.6217	35.6783
SK-BR-3	CTRP2	0.8782	8.5556	-0.7793	32.9036
MDA-MB-361	CTRP2	1.1241	10.7172	-1.478	33.8504
MDA-MB-361	CTRP2	1.1988	4.8563	1.0268	32.8451
HCC1954	CTRP2	1.2618	3.8829	1.2193	32.0038
CAL-85-1	CTRP2	1.3031	3.506	1.2562	25.083
AU565	CTRP2	1.3429	11.2192	-6.0284	18.9988
MDA-MB-468	CTRP2	1.3502	2.3697	1.3498	24.6127
DU4475	CTRP2	1.3688	1.9658	1.3688	31.1492
BT-474	CTRP2	1.4092	3.535	1.365	24.3671
MDA-MB-453	CTRP2	1.5022	3.3463	1.4779	23.68
MDA-MB-468	CTRP2	1.5599	2.1333	1.5599	29.8765
DU4475	CTRP2	1.7074	2.2382	1.7074	22.2314
HCC38	CTRP2	1.7963	3.9551	1.7706	28.3877
HDQ-P1	CTRP2	1.805	4.2012	1.7612	28.3902
HCC1500	CTRP2	1.9161	2.8047	1.9161	27.5032
HCC1500	CTRP2	1.9512	3.2933	1.9435	20.6329
MDA-MB-453	CTRP2	1.9774	2.8256	1.9773	27.0953
HCC202	CTRP2	2.0302	5.7026	1.752	27.6927
HCC1143	CTRP2	2.104	4.6001	2.0353	26.4836
HCC1419	CTRP2	2.1452	9.6295	0.0426	26.7434
BT-20	CTRP2	2.1634	3.5441	2.1608	25.8643
HCC1395	CTRP2	2.1968	3.3005	2.1963	25.6348
BT-549	CTRP2	2.2676	4.0123	2.2209	18.6575
KPL-1	CTRP2	2.2961	3.0937	2.2961	24.9715
HCC1937	CTRP2	2.3196	3.6975	2.3163	24.8264
T-47D	CTRP2	2.3509	3.6412	2.3487	24.6139
CAL-148	CTRP2	2.397	3.0498	2.397	24.2996
JIMT-1	CTRP2	2.4018	3.0477	2.4018	24.2674
ZR-75-1	CTRP2	2.4446	5.2222	2.1567	19.6412
HCC202	CTRP2	2.4795	7.3248	1.4088	21.0309
HMC-1-8	CTRP2	2.4905	2.8996	2.4905	23.6766
HCC1806	CTRP2	2.5246	4.667	2.4732	23.6226
CAL-51	CTRP2	2.5836	3.3308	2.5836	23.0564
Hs 578Bst	CTRP2	2.8035	5.2665	2.5347	15.878
BT-549	CTRP2	2.8064	4.4007	2.7898	21.6275
HCC38	CTRP2	2.9504	5.6427	2.5717	15.3089
HCC1143	CTRP2	2.9738	5.5541	2.6275	15.033
ZR-75-1	CTRP2	3.3239	5.1972	3.123	12.1707
CAL-51	CTRP2	3.5288	4.4094	3.5109	10.1575
MDA-MB-231	CTRP2	3.573	4.569	3.539	9.918
HCC1428	CTRP2	3.8217	5.0821	3.7984	14.8861
HCC1428	CTRP2	4.1959	5.6277	3.9128	6.6974
T-47D	CTRP2	4.3075	9.2204	2.3144	12.9564
BT-20	CTRP2	4.7428	8.2292	3.1942	8.3785
CAMA-1	CTRP2	5.432	6.1084	5.3576	4.3427
MCF-7	CTRP2	5.5383	7.2381	4.9869	5.5291
BT 271	CTRP2	-0.3206	3.8035	-0.4429	42.694
BT 239	CTRP2	-0.2045	2.6676	-0.2263	41.6933
BT 231	CTRP2	0.2675	4.032	0.1538	38.8196
BT164	CTRP2	0.434	4.1355	0.3176	37.7295
BT 112	CTRP2	0.4946	4.1951	0.3741	37.3414
BT 139	CTRP2	0.5818	3.9549	0.4967	36.6598
BT 145	CTRP2	0.6646	4.959	0.43	36.5519
BT 231	CTRP2	1.0992	3.0107	1.0807	26.3455
BT 239	CTRP2	1.1061	3.0029	1.0883	26.297
BT 172	CTRP2	1.1593	3.4203	1.1416	32.6038
BT 271	CTRP2	1.2117	3.8375	1.1187	25.8488
BT164	CTRP2	1.2864	1.8712	1.2864	25.0365
BT 159	CTRP2	1.3348	3.2364	1.3114	24.7923
BT 139	CTRP2	1.3424	2.8761	1.3355	24.6865
BT147	CTRP2	1.3474	3.8031	1.2684	24.8973
BT 428	CTRP2	1.3673	2.1783	1.3673	24.4973
BT 112	CTRP2	1.3859	2.5395	1.385	24.3764
BT 228	CTRP2	1.3999	2.9968	1.3903	24.3121
BT 145	CTRP2	1.4148	2.025	1.4148	24.1812
BT 330	CTRP2	1.4191	3.4249	1.3853	24.2656
BT 504	CTRP2	1.4515	2.0284	1.4515	23.9364
BT 286	CTRP2	1.4558	2.0394	1.4558	23.908
BT 416	CTRP2	1.4759	2	1.4759	23.7739
BT 428	CTRP2	1.4774	3.0953	1.4745	30.4357
BT 172	CTRP2	1.4828	3.216	1.4657	23.7852
BT 245	CTRP2	1.5266	3.1782	1.5128	23.4823
BT 131	CTRP2	1.5441	2.0065	1.5441	23.3196
BT147	CTRP2	1.5978	3.1287	1.5955	29.6314
BT 187	CTRP2	1.6415	3.7656	1.5859	22.8586
BT 187	CTRP2	1.6663	4.1286	1.6221	29.3157
BT 232	CTRP2	1.7199	3.9941	1.6887	28.9148
BT 444	CTRP2	1.8199	3.6239	1.7881	21.5891
BT 228	CTRP2	1.8739	3.9867	1.8491	27.8674
BT 416	CTRP2	1.8798	2.7141	1.8798	27.745
BT 286	CTRP2	1.8897	2.583	1.8897	27.6789
BT 498	CTRP2	1.9382	5.1974	1.6116	21.8384
BT 340	CTRP2	2.0141	3.7917	1.9768	20.3139
BT 131	CTRP2	2.0526	3.0944	2.0524	26.5946
BT 440	CTRP2	2.0644	2.9045	2.0644	26.5153
BT 504	CTRP2	2.0817	2.9465	2.0817	26.4003
BT 359	CTRP2	2.1566	4.1661	2.0819	19.4928
BT 248	CTRP2	2.1777	3.5427	2.1753	25.7686
BT 179	CTRP2	2.1844	2.9249	2.1844	25.7161
BT 245	CTRP2	2.2002	3.326	2.1996	25.6126
BT 159	CTRP2	2.2059	4.5095	2.1534	25.7495
BT 359	CTRP2	2.2062	3.2742	2.2058	25.572
BT 340	CTRP2	2.3042	3.4719	2.3033	24.9206
BT 216	CTRP2	2.3421	3.0517	2.342	24.6656
BT 328	CTRP2	2.3451	2.8587	2.3451	24.6453
BT 444	CTRP2	2.3491	3.0429	2.3491	24.6189
BT 333	CTRP2	2.3678	4.1486	2.3103	18.0266
BT 333	CTRP2	2.4082	3.917	2.4013	24.248
BT 224	CTRP2	2.4404	5.3392	2.2789	24.5632
BT 482	CTRP2	2.441	3.1676	2.441	24.0063
BT 498	CTRP2	2.5221	3.0539	2.5221	23.4661
BT 320	CTRP2	2.5251	3.3183	2.5251	23.4462
BT 422	CTRP2	2.6378	2.9843	2.6378	22.695
BT 179	CTRP2	2.6682	5.3027	2.3763	16.862
BT 224	CTRP2	2.7015	4.6538	2.5826	16.0179
BT 232	CTRP2	2.7763	5.8785	2.3	16.829
BT 440	CTRP2	2.9157	4.4719	2.8488	14.4099
BT 216	CTRP2	3.3319	5.6578	2.9782	12.6849
BT 422	CTRP2	3.6006	4.0483	3.6003	9.6196
BT 328	CTRP2	3.618	5.9131	3.1872	11.085
BT 320	CTRP2	4.3364	6.4645	3.6832	7.2525

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
YD-38	CTRP2	0.9898	2.2398	0.9896	33.675

Cancer Drug Sensitivity Data Curated from 67 Cell Line(s) in Central Nervous System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
LN-229	CTRP2	-0.1634	1.3317	-0.1635	41.3577
CAS-1	CTRP2	1.2919	3.6409	1.2671	31.7446
D283 Med	CTRP2	1.445	2.0773	1.445	23.98
SF539	CTRP2	1.4733	3.2245	1.4555	23.8509
KNS-60	CTRP2	1.5437	2.1135	1.5437	29.9843
SNB-75	CTRP2	1.5995	3.84	1.5322	23.1784
M059K	CTRP2	1.7337	3.1644	1.7257	22.0829
SNB-75	CTRP2	1.8294	3.9996	1.8021	28.1725
SF268	CTRP2	1.8521	3.656	1.8191	21.3784
D283 Med	CTRP2	1.979	3.3814	1.9768	27.0916
42-MG-BA	CTRP2	1.9826	3.415	1.9708	20.4374
SF539	CTRP2	2.153	3.1308	2.1528	25.9258
SF268	CTRP2	2.1549	3.3951	2.1537	25.9165
KNS-60	CTRP2	2.1662	4.7316	1.9829	19.8091
M059K	CTRP2	2.174	2.7776	2.174	25.7849
Hs 683	CTRP2	2.1962	2.8208	2.1962	25.6372
U-118MG	CTRP2	2.2067	2.9951	2.2067	25.5672
GB-1	CTRP2	2.237	3.2701	2.2367	25.3664
GOS-3	CTRP2	2.2714	2.826	2.2714	25.1363
Daoy	CTRP2	2.2823	2.9945	2.2823	25.0636
DK-MG	CTRP2	2.2867	4.0972	2.2697	25.0911
GMS-10	CTRP2	2.3219	2.7548	2.3219	24.7996
SNU-201	CTRP2	2.3297	3.3054	2.3295	24.7483
KG-1-C	CTRP2	2.3613	3.0317	2.3613	24.5375
42-MG-BA	CTRP2	2.3888	2.9804	2.3888	24.3541
SNU-738	CTRP2	2.3965	3.0611	2.3965	24.3025
TM-31	CTRP2	2.4313	2.8391	2.4313	24.0709
SF126	CTRP2	2.4348	2.9039	2.4348	24.048
U-251MG	CTRP2	2.4521	3.0657	2.4521	23.9323
SNU-489	CTRP2	2.4901	2.9901	2.4901	23.6794
ONS-76	CTRP2	2.5072	3.7056	2.5056	23.5707
T98G	CTRP2	2.5541	3.4306	2.554	23.253
YKG-1	CTRP2	2.5812	2.9513	2.5812	23.0722
KNS-42	CTRP2	2.5943	2.9774	2.5943	22.9852
YH-13	CTRP2	2.5983	3.0235	2.5983	22.9581
A-172	CTRP2	2.6545	9.8032	0.4661	23.9715
SW1088	CTRP2	2.7265	4.1905	2.7174	22.1345
CCF-STTG1	CTRP2	2.8049	4.1583	2.7985	21.6036
Becker	CTRP2	2.8436	4.5854	2.8161	21.4165
NMC-G1	CTRP2	2.9231	4.115	2.9197	20.8057
SW1088	CTRP2	2.9949	4.6818	2.8953	13.9966
DK-MG	CTRP2	3.0506	5.0363	2.8707	13.9119
GaMG	CTRP2	3.1137	4.0764	3.1126	19.5284
KNS-81	CTRP2	3.2121	4.1558	3.2109	18.873
SW1783	CTRP2	3.2901	5.7636	3.1103	18.9725
GMS-10	CTRP2	3.314	5.6738	2.9531	12.8309
KNS-81	CTRP2	3.337	4.0557	3.3334	11.387
SNU-1105	CTRP2	3.3939	5.9247	3.1836	18.3903
GaMG	CTRP2	3.4076	4.08	3.4047	10.914
KG-1-C	CTRP2	3.4814	5.0907	3.3258	10.959
Hs 683	CTRP2	3.5177	5.4349	3.2573	11.103
KALS-1	CTRP2	3.8096	4.8651	3.7412	8.4622
U-251MG	CTRP2	3.8621	7.3949	2.7812	12.0695
SW1783	CTRP2	3.9231	9.7022	1.7258	16.1867
U-118MG	CTRP2	3.9644	5.7208	3.6308	8.4216
YH-13	CTRP2	4.0077	6.5923	3.2978	9.6228
TM-31	CTRP2	4.129	6.414	3.5009	8.5019
DBTRG-05MG	CTRP2	4.2479	5.2681	4.1052	5.818
GOS-3	CTRP2	4.6239	8.5353	2.9372	9.7007
Becker	CTRP2	5.0555	8.5582	3.2967	7.3238
DBTRG-05MG	CTRP2	5.3492	12.8303	2.0561	17.8201
U-87MG ATCC	CTRP2	5.515	5.9463	5.4902	3.6121
YKG-1	CTRP2	6.245	9.6206	3.6629	3.857
8-MG-BA	CTRP2	6.283	10.3463	3.3412	5.0902
CCF-STTG1	CTRP2	6.4739	11.4468	2.9421	6.4185
KNS-42	CTRP2	6.815	10.7363	3.5038	3.749
T98G	CTRP2	9.9707	20.5632	0.9051	9.3639

Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Endometrium Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JHUEM-3	CTRP2	1.0846	4.2734	0.9064	26.9876
JHUEM-3	CTRP2	1.6682	5.2334	1.463	29.8447
JHUEM-7	CTRP2	1.731	3.0109	1.7271	22.0871
AN3-CA	CTRP2	1.7838	3.0429	1.78	21.7353
JHUEM-1	CTRP2	1.8633	2.3664	1.8633	21.1928
AN3-CA	CTRP2	1.8988	2.7115	1.8988	27.6184
HEC-1-B	CTRP2	1.9304	5.7131	1.6406	28.3936
RL95-2	CTRP2	2.0066	3.3992	2.0044	26.9078
EFE-184	CTRP2	2.1052	28.6776	-9.303	40.9508
HEC-251	CTRP2	2.111	4.4695	2.0574	26.3854
JHUEM-1	CTRP2	2.1304	2.6925	2.1304	26.0757
JHUEM-7	CTRP2	2.1919	3.4392	2.1906	25.67
EN	CTRP2	2.1921	2.7892	2.1921	25.6644
HEC-1-A	CTRP2	2.213	3.1592	2.2128	25.526
MFE-296	CTRP2	2.4485	3.3973	2.4483	23.9568
ESS-1	CTRP2	2.449	3.0571	2.449	23.9531
HEC-6	CTRP2	2.5358	3.9482	2.5304	23.3927
HEC-151	CTRP2	2.5898	3.3751	2.5897	23.0155
HEC-59	CTRP2	2.5921	3.9736	2.5869	23.0169
HEC-1-A	CTRP2	2.7159	5.0194	2.51	16.2321
HEC-108	CTRP2	2.735	3.5272	2.7349	22.0478
HEC-50B	CTRP2	2.7717	4.4332	2.752	21.8691
MFE-319	CTRP2	3.0066	4.3254	2.999	20.2638
HEC-151	CTRP2	3.389	4.4244	3.3617	11.1207
EFE-184	CTRP2	3.4878	5.0971	3.4445	17.1788
MFE-296	CTRP2	3.6709	5.7788	3.2963	10.5193
ESS-1	CTRP2	5.8729	10.557	2.9444	7.3429
HEC-50B	CTRP2	6.0276	8.5334	4.0354	2.6763
MFE-319	CTRP2	6.1039	9.8283	3.4675	4.8401
EN	CTRP2	6.577	9.2951	4.0196	2.0966
Ishikawa (Heraklio) 02 ER-	CTRP2	3.7671	5.5416	3.6762	15.483

Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Kidney Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
TUHR14TKB	CTRP2	0.7654	6.467	0.1626	36.892
CAL-54	CTRP2	1.0245	2.8643	1.0108	26.8271
UO-31	CTRP2	1.1174	3.4998	1.0609	26.3528
UO-31	CTRP2	1.4681	4.1918	1.4078	30.6893
TUHR14TKB	CTRP2	1.5326	5.5589	1.0599	50.1902
CAL-54	CTRP2	1.5606	4.0317	1.5196	30.009
KMRC-3	CTRP2	1.6239	3.3837	1.6018	22.8621
VMRC-RCW	CTRP2	1.9294	3.8815	1.8776	20.9275
KMRC-3	CTRP2	2.0276	3.3378	2.0261	26.7655
769-P	CTRP2	2.0774	5.3471	1.8836	27.0894
KMRC-2	CTRP2	2.2126	3.8694	2.1781	18.9821
VMRC-RCZ	CTRP2	2.229	2.935	2.229	25.4185
KMRC-2	CTRP2	2.3218	2.8336	2.3218	24.8007
KMRC-1	CTRP2	2.3271	2.91	2.3271	24.7651
KMRC-20	CTRP2	2.3557	4.3434	2.3256	24.6756
VMRC-RCZ	CTRP2	2.3596	4.4934	2.2443	18.2821
Caki-2	CTRP2	2.3687	3.1012	2.3687	24.488
ACHN	CTRP2	2.3832	4.108	2.3686	24.4404
TUHR4TKB	CTRP2	2.3838	3.981	2.3744	24.4188
786-O	CTRP2	2.4215	3.027	2.4215	24.1364
VMRC-RCW	CTRP2	2.4591	3.4615	2.4588	23.8866
A-498	CTRP2	2.5828	3.2441	2.5828	23.0617
OS-RC-2	CTRP2	2.6017	3.905	2.5982	22.9474
TUHR10TKB	CTRP2	2.6463	3.1078	2.6463	22.6389
RCC10RGB	CTRP2	2.7024	4.303	2.6877	22.3138
BFTC-909	CTRP2	2.7281	4.1179	2.7214	22.1161
SNU-1272	CTRP2	3.1355	4.5439	3.1219	19.425
Caki-2	CTRP2	3.2191	5.9688	2.7411	13.9036
Caki-1	CTRP2	3.2305	7.0994	2.6324	20.8958
TUHR10TKB	CTRP2	3.2909	4.3183	3.2694	11.7543
ACHN	CTRP2	3.3049	6.4758	2.6274	14.1072
A-498	CTRP2	3.7549	5.8772	3.3465	10.0939
KMRC-1	CTRP2	4.1361	7.1964	3.1418	9.9419
786-O	CTRP2	4.8346	7.7254	3.5253	6.8022
Caki-1	CTRP2	5.3293	10.8632	2.3689	10.6696
RCC10RGB	CTRP2	7.2513	14.3197	2.0921	8.6396

Cancer Drug Sensitivity Data Curated from 72 Cell Line(s) in Large Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SW48	CTRP2	-0.0939	3.3513	-0.1553	41.0643
CCK-81	CTRP2	0.5071	2.8011	0.4804	30.3173
CW-2	CTRP2	0.7967	3.5781	0.7573	35.0894
CW-2	CTRP2	0.988	4.3083	0.7946	27.6822
HCC-56	CTRP2	1.0331	1.7852	1.0331	33.3857
SW1116	CTRP2	1.1058	3.5625	1.0417	26.4556
HT115	CTRP2	1.1894	2.3215	1.1894	32.3447
NCI-H747	CTRP2	1.3638	4.2919	1.2053	25.0626
COLO 320	CTRP2	1.496	3.2337	1.4909	30.3191
SW1116	CTRP2	1.4985	2.8134	1.4979	30.2877
NCI-H716	CTRP2	1.5208	2.7475	1.5187	23.4816
HT-55	CTRP2	1.5865	3.0454	1.5849	29.7046
T84	CTRP2	1.6043	2.895	1.6037	29.5825
NCI-H747	CTRP2	1.6288	3.4032	1.622	29.4402
GP2d	CTRP2	1.672	5.401	1.2607	23.9083
COLO 678	CTRP2	1.6992	5.2419	1.3379	23.5491
LoVo	CTRP2	1.759	4.3472	1.6224	22.3555
HT-55	CTRP2	1.7778	3.3309	1.764	21.8088
LoVo	CTRP2	1.786	4.2157	1.74	28.5244
COLO 320	CTRP2	1.7935	5.0726	1.4888	22.7207
NCI-H716	CTRP2	1.8474	3.9099	1.8262	28.0322
SNU-503	CTRP2	1.8717	5.4992	1.6271	28.6284
C2BBe1	CTRP2	1.8765	3.6572	1.8671	27.7986
GP2d	CTRP2	1.9349	3.3782	1.9324	27.3865
C2BBe1	CTRP2	1.9456	4.6069	1.7712	21.246
SNU-C2A	CTRP2	2.0028	4.4757	1.9424	27.1289
SNU-1033	CTRP2	2.0288	4.7342	1.8326	20.7695
SNU-407	CTRP2	2.1039	4.3977	2.0571	26.4095
SK-CO-1	CTRP2	2.1231	2.9988	2.123	26.1245
COLO 678	CTRP2	2.138	3.9807	2.1222	26.0779
SW948	CTRP2	2.1761	3.8132	2.1678	25.7987
HCT 15	CTRP2	2.2299	2.9376	2.2299	25.4124
SW1417	CTRP2	2.2303	4.7657	2.1486	25.6869
T84	CTRP2	2.2458	4.5748	2.1044	19.131
SNU-C1	CTRP2	2.2671	4.4508	2.2237	25.3109
SNU-1033	CTRP2	2.2746	3.444	2.2737	25.1179
SNU-503	CTRP2	2.2808	5.0397	2.0297	19.2889
LS123	CTRP2	2.3096	3.3603	2.3092	24.8828
SNU-C4	CTRP2	2.3117	3.0548	2.3117	24.8679
LS513	CTRP2	2.3659	3.0233	2.3659	24.5065
SNU-C5	CTRP2	2.4405	3.6393	2.439	24.0148
OUMS-23	CTRP2	2.5242	2.9215	2.5242	23.4523
RCM-1 [Human ESC]	CTRP2	2.7034	3.662	2.703	22.2594
SNU-61	CTRP2	2.7904	4.0808	2.7858	21.6938
LS180	CTRP2	2.832	4.9947	2.7595	21.6475
LS411N	CTRP2	2.8438	3.8332	2.843	21.3256
DLD-1	CTRP2	2.8605	3.329	2.8605	21.2117
LS1034	CTRP2	2.954	4.5077	2.9364	20.6477
SNU-407	CTRP2	2.9971	4.7608	2.8807	14.0414
SNU-C5	CTRP2	3.0446	4.6976	2.9459	13.6625
SW620	CTRP2	3.0566	5.0123	2.9967	20.108
SNU-61	CTRP2	3.1057	10.3697	0.6331	22.2394
NCI-H508	CTRP2	3.1099	4.5866	3.0383	13.1326
SNU-C1	CTRP2	3.1283	12.8135	-0.5333	25.9574
LS123	CTRP2	3.1736	13.23	-0.6958	26.3192
SNU-C4	CTRP2	3.3168	5.0077	3.169	12.0255
CL-11	CTRP2	3.4226	5.0871	3.2627	11.3653
LS1034	CTRP2	3.5113	4.891	3.4105	10.5631
HCT 15	CTRP2	3.6158	5.8109	3.225	10.9457
COLO201	CTRP2	3.6281	4.0131	3.628	9.4362
KM12	CTRP2	3.7645	4.5523	3.7449	8.5931
RKO	CTRP2	3.8301	4.6183	3.8066	8.1693
SW948	CTRP2	3.9426	7.2128	2.9456	11.2065
SW620	CTRP2	4.2046	6.1486	3.6974	7.5232
HCT 8	CTRP2	4.2288	4.9759	4.172	5.6306
HCT 8	CTRP2	4.2528	6.0609	4.0846	12.5249
RCM-1 [Human ESC]	CTRP2	4.8648	7.9203	3.4541	7.0392
SW1417	CTRP2	4.925	9.9622	2.4853	10.9662
MDST8	CTRP2	5.0545	8.2636	4.0308	10.5898
COLO205	CTRP2	5.3731	6.5569	5.1282	5.3798
HCC-56	CTRP2	6.3618	7.5946	4.6293	0.3411
MDST8	CTRP2	7.2497	8.5145	4.6392	0.0823

Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Liver Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SNU-182	CTRP2	1.0307	2.9491	1.0252	33.4202
JHH-5	CTRP2	1.0801	3.385	1.0332	26.5685
SNU-761	CTRP2	1.4439	2.6715	1.4436	30.6505
JHH-4	CTRP2	1.4943	2.1176	1.4943	30.3136
HuH-6	CTRP2	1.5541	4.0079	1.5148	30.0465
JHH-4	CTRP2	1.635	2.8499	1.6327	22.7217
Li-7	CTRP2	1.8027	3.4683	1.7971	28.2773
SNU-878	CTRP2	1.8814	3.2464	1.8798	27.7398
SNU-761	CTRP2	1.9875	3.833	1.9445	20.5107
JHH-5	CTRP2	1.9898	3.9855	1.9691	27.0817
JHH-2	CTRP2	2.0219	3.6451	1.9976	20.2182
SNU-398	CTRP2	2.1383	3.8074	2.1294	26.0527
HuH-1	CTRP2	2.2792	3.0046	2.2792	25.084
SNU-387	CTRP2	2.323	4.1577	2.2612	18.3398
JHH-2	CTRP2	2.3398	3.0179	2.3398	24.6803
JHH-1	CTRP2	2.3726	2.8848	2.3726	24.4619
SNU-423	CTRP2	2.4302	3.0303	2.4302	24.0785
HLF	CTRP2	2.4569	2.9274	2.4569	23.9003
SK-HEP-1	CTRP2	2.5351	3.1362	2.5351	23.3796
SNU-449	CTRP2	2.5496	3.8752	2.5306	16.6845
Hep-G2	CTRP2	2.6921	3.6946	2.6869	15.6889
PLC/PRF/5	CTRP2	2.7664	3.6406	2.7662	21.8389
JHH-6	CTRP2	2.8064	3.2295	2.8064	21.5722
SNU-449	CTRP2	2.8255	4.4141	2.8088	21.5009
SNU-423	CTRP2	2.934	5.0407	2.7423	14.7301
SNU-398	CTRP2	3.0113	6.3857	2.356	15.9566
HLF	CTRP2	3.094	5.5648	2.7541	14.2113
SNU-475	CTRP2	3.124	4.2338	3.1209	19.4663
HuH-1	CTRP2	3.533	5.3666	3.2969	10.911
JHH-1	CTRP2	3.8157	6.3615	3.206	10.4807
Hep-G2	CTRP2	4.0166	5.2295	3.8673	7.9048
SNU-886	CTRP2	4.336	6.1352	1.4775	0.4523
PLC/PRF/5	CTRP2	4.6967	7.5947	3.4691	7.3245
SNU-475	CTRP2	5.0184	8.8307	3.1296	8.0968
Hep 3B2.1-7	CTRP2	5.0468	6.3141	4.8717	7.2732
SK-HEP-1	CTRP2	6.2727	9.8298	3.5817	4.1421
JHH-6	CTRP2	6.3656	7.5951	4.6307	0.3361

Cancer Drug Sensitivity Data Curated from 221 Cell Line(s) in Lung Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H1666	CTRP2	-8.745	4.2139	-9.6353	75.0996
HCC827	CTRP2	-7.1589	-3.1546	-7.1615	84.1396
NCI-H1975	CTRP2	-5.3965	-0.8334	-5.4133	73.9952
PC-14	CTRP2	-4.3118	-1.5014	-4.3126	68.7761
PC-14	CTRP2	-4.0722	-2.2829	-4.0722	60.7324
HCC4006	CTRP2	-3.9566	0.8639	-4.0279	59.2899
HCC4006	CTRP2	-2.1986	2.167	-2.2604	54.6914
HCC2935	CTRP2	-1.6398	2.8792	-1.7934	44.8153
NCI-H1693	CTRP2	-1.6114	3.9007	-1.8381	50.9082
HCC2935	CTRP2	-0.7453	2.6996	-0.786	45.3153
NCI-H292	CTRP2	-0.1136	3.2895	-0.1707	41.1835
EPLC-272H	CTRP2	0.1697	4.6862	-0.0537	39.7426
COR-L105	CTRP2	0.1993	3.1239	0.1668	39.0406
NCI-H2291	CTRP2	0.4244	5.407	0.0727	38.4196
CAL-12T	CTRP2	0.5238	3.6715	0.4643	36.9664
NCI-H1666	CTRP2	0.5598	3.0668	0.5158	30.0242
Calu-3	CTRP2	0.6675	2.9878	0.6546	35.8642
NCI-H1623	CTRP2	0.6833	3.7767	0.5616	29.4633
SK-MES-1	CTRP2	0.7091	2.8977	0.6837	28.9673
NCI-H2228	CTRP2	0.7268	6.6888	-0.2004	31.7676
DV-90	CTRP2	0.7625	3.0455	0.7497	35.2307
EKVX	CTRP2	0.7968	3.4863	0.7229	28.5466
EKVX	CTRP2	0.9154	4.2895	0.8102	34.5102
NCI-H1693	CTRP2	0.9613	3.0421	0.9362	27.2865
COR-L105	CTRP2	0.9974	3.02	0.975	27.0367
NCI-H2171	CTRP2	1.0063	2.283	1.0061	33.5652
LUDLU-1	CTRP2	1.032	3.4812	1.0074	33.4746
NCI-H211	CTRP2	1.0521	3.1379	1.0423	33.2918
NCI-H2170	CTRP2	1.11	3.7366	1.0721	32.9993
COR-L51	CTRP2	1.1712	2.6205	1.1704	32.4687
HCC44	CTRP2	1.1781	2.9436	1.1743	32.4328
NCI-H1623	CTRP2	1.1867	4.1977	1.1098	32.6169
NCI-H1341	CTRP2	1.2613	2.6561	1.2606	31.8682
NCI-H1563	CTRP2	1.3067	3.7864	1.2273	25.1696
NCI-H358	CTRP2	1.3347	2.8557	1.3332	31.3818
NCI-H1650	CTRP2	1.3447	4.6017	1.2252	31.7068
NCI-H1568	CTRP2	1.3597	2.7919	1.3552	24.563
NCI-H322	CTRP2	1.4013	3.6672	1.3427	24.4687
NCI-H1341	CTRP2	1.4019	2.0713	1.4019	24.2665
NCI-H2106	CTRP2	1.4086	2.5204	1.4085	30.8848
NCI-H2141	CTRP2	1.4179	4.3111	1.3417	31.0763
NCI-H2009	CTRP2	1.485	3.4573	1.4739	30.4122
NCI-H1915	CTRP2	1.4885	3.5103	1.4755	30.3954
NCI-H810	CTRP2	1.4997	2.6613	1.4995	30.2783
NCI-H1435	CTRP2	1.507	3.0895	1.5043	30.2378
NCI-H2085	CTRP2	1.5163	2.7841	1.5158	30.1684
NCI-H810	CTRP2	1.5263	2.0633	1.5263	23.4381
DV-90	CTRP2	1.5286	3.026	1.5208	23.4487
NCI-H841	CTRP2	1.539	2.2682	1.539	30.0153
NCI-H1435	CTRP2	1.5456	3.4728	1.5137	50.0668
NCI-H510A	CTRP2	1.5732	2.4695	1.5731	23.126
HOP-92	CTRP2	1.5925	4.928	1.3084	23.9825
NCI-H2081	CTRP2	1.5975	2.5921	1.5975	29.626
NCI-H2110	CTRP2	1.5975	3.2868	1.5927	29.6419
HCC95	CTRP2	1.6039	4.5706	1.5067	29.9092
NCI-H1184	CTRP2	1.6039	3.4822	1.5739	23.0216
EPLC-272H	CTRP2	1.6099	3.8664	1.5399	23.1182
COR-L88	CTRP2	1.6107	4.3578	1.5406	29.7726
NCI-H661	CTRP2	1.6116	6.2342	1.1536	31.0488
COR-L95	CTRP2	1.6298	3.1843	1.627	29.4202
NCI-H1155	CTRP2	1.6429	2.2557	1.6429	29.3231
NCI-H1838	CTRP2	1.6615	3.7217	1.6441	29.2577
NCI-H322	CTRP2	1.7127	2.6363	1.7127	28.8583
NCI-H522	CTRP2	1.7144	4.2368	1.5946	22.5942
NCI-H1105	CTRP2	1.7145	3.5183	1.7061	28.8743
LOU-NH91	CTRP2	1.754	4.2745	1.7007	28.7622
NCI-H1755	CTRP2	1.7545	15.3319	-3.0452	35.1797
NCI-H1184	CTRP2	1.762	2.7751	1.7619	28.5302
NCI-H2170	CTRP2	1.7704	5.1966	1.4287	23.0066
NCI-H1694	CTRP2	1.7811	2.9923	1.7782	21.7501
NCI-H1568	CTRP2	1.7856	2.7973	1.7855	28.3728
NCI-H526	CTRP2	1.7902	2.6297	1.7902	28.3421
NCI-H1755	CTRP2	1.7961	3.3122	1.7932	28.3122
NCI-H2085	CTRP2	1.8245	3.6128	1.7939	21.5543
NCI-H2081	CTRP2	1.836	4.3883	1.6978	21.8486
NCI-H2342	CTRP2	1.8723	3.9872	1.8474	27.8783
HOP-62	CTRP2	1.9044	4.057	1.8762	27.6757
NCI-H1694	CTRP2	1.9161	2.7558	1.9161	27.5036
HOP-92	CTRP2	1.9201	4.2091	1.881	27.6079
EBC-1	CTRP2	1.9408	2.8788	1.9408	27.3387
SK-MES-1	CTRP2	1.9559	3.3437	1.954	27.2443
NCI-H2029	CTRP2	1.9708	4.2287	1.9325	27.2673
NCI-H23	CTRP2	1.9725	2.957	1.9724	27.1276
LXF 289	CTRP2	1.9825	3.5989	1.9599	20.4746
NCI-H446	CTRP2	1.9928	2.9663	1.9928	26.9923
Lu-65	CTRP2	2.0397	3.6468	2.0336	26.7005
NCI-H522	CTRP2	2.0402	4.6158	1.9656	26.9283
HOP-62	CTRP2	2.0502	4.5108	1.9054	20.4456
Sq-1	CTRP2	2.0534	3.0027	2.0533	26.5889
NCI-H2196	CTRP2	2.0661	2.9223	2.066	26.5043
NCI-H1581	CTRP2	2.0736	3.1748	2.0732	26.4552
NCI-H1563	CTRP2	2.0892	3.8773	2.0767	26.3919
HCC2279	CTRP2	2.0978	4.0036	2.0796	26.3536
EBC-1	CTRP2	2.0978	3.7391	2.0694	19.7263
Sq-1	CTRP2	2.0985	4.0185	2.0404	19.8226
NCI-H1869	CTRP2	2.1006	4.3672	2.0565	26.4225
COLO 668	CTRP2	2.1091	3.134	2.1089	26.2179
COR-L51	CTRP2	2.121	4.2054	2.0377	19.7594
HCC366	CTRP2	2.1263	3.4879	2.1241	26.1105
NCI-H520	CTRP2	2.1312	3.2098	2.1309	26.0714
ChaGo-K-1	CTRP2	2.1379	2.9829	2.1378	26.0259
A-549	CTRP2	2.1446	4.065	2.1246	26.0481
T3M-10	CTRP2	2.1572	3.0989	2.1571	25.8975
NCI-H2087	CTRP2	2.1588	4.6921	1.984	19.8284
DMS 273	CTRP2	2.1595	3.6817	2.1544	25.8987
NCI-H1944	CTRP2	2.1679	3.9439	2.1232	19.3146
VMRC-LCD	CTRP2	2.1849	3.4169	2.1837	25.7166
RERF-LC-MS	CTRP2	2.1964	2.9557	2.1964	25.6357
DMS 53	CTRP2	2.1991	3.9122	2.1879	25.6553
NCI-H647	CTRP2	2.226	3.4366	2.2249	25.4424
RERF-LC-A1	CTRP2	2.2313	3.4966	2.2298	25.4083
HCC1833	CTRP2	2.2374	3.2124	2.2373	25.3631
NCI-H1703	CTRP2	2.2512	3.0063	2.2512	25.2707
NCI-H1944	CTRP2	2.2743	3.233	2.2741	25.1175
Lu-99	CTRP2	2.2961	3.0376	2.2961	24.9718
RERF-LC-Ad2	CTRP2	2.2987	3.9674	2.2879	24.9904
HCC1588	CTRP2	2.3011	2.9296	2.3011	24.9386
NCI-H1355	CTRP2	2.3386	4.2247	2.2682	18.2658
LXF 289	CTRP2	2.3556	3.6871	2.3529	24.5844
HARA [Human squamous cell lung carcinoma]	CTRP2	2.3585	4.1307	2.342	24.6113
NCI-H1651	CTRP2	2.3659	4.083	2.3519	24.5536
NCI-H1092	CTRP2	2.3859	3.1363	2.3859	24.3732
DMS 114	CTRP2	2.4219	3.0524	2.4219	24.1334
HCC15	CTRP2	2.4517	4.081	2.4401	23.9738
NCI-H1793	CTRP2	2.4611	3.8368	2.457	23.8863
NCI-H196	CTRP2	2.4675	4.4254	2.4359	23.9359
HCC1438	CTRP2	2.4981	3.9834	2.491	23.6498
NCI-H838	CTRP2	2.5009	3.9532	2.4947	23.628
DMS 454	CTRP2	2.5251	3.4084	2.5249	23.4468
LCLC-103H	CTRP2	2.5325	2.9597	2.5325	23.3969
NCI-H2342	CTRP2	2.5393	5.1552	2.2795	17.6017
T3M-10	CTRP2	2.5425	4.665	2.4075	17.1334
SHP-77	CTRP2	2.5569	3.4097	2.5568	23.2344
LOU-NH91	CTRP2	2.5592	4.5505	2.4493	16.934
NCI-H1395	CTRP2	2.5695	3.7937	2.5674	23.1573
LK2	CTRP2	2.5818	2.8481	2.5818	23.0683
HCC1171	CTRP2	2.5883	6.0912	2.2597	24.1683
NCI-H661	CTRP2	2.6156	4.4887	2.5222	16.5006
NCI-H2444	CTRP2	2.6216	3.9442	2.6176	22.8165
NCI-H1650	CTRP2	2.625	8.2862	1.1364	21.6543
NCI-H2228	CTRP2	2.6325	4.1422	2.623	22.762
COLO 699	CTRP2	2.6577	5.181	2.5432	22.9533
NCI-H841	CTRP2	2.6582	4.863	2.4875	16.4897
HCC1195	CTRP2	2.6672	7.2436	1.6384	19.651
IA-LM	CTRP2	2.6846	4.3055	2.6692	22.4351
NCI-H2126	CTRP2	2.687	3.8305	2.6759	15.7425
HCC78	CTRP2	2.6891	4.1315	2.6813	22.3795
NCI-H2029	CTRP2	2.7353	4.4732	2.6543	15.6603
NCI-H2405	CTRP2	2.7442	6.727	2.2357	23.7796
LUDLU-1	CTRP2	2.7786	5.6677	2.3772	16.5332
NCI-H209	CTRP2	2.7884	4.8989	2.6205	15.6132
NCI-H1703	CTRP2	2.7965	5.4958	2.4546	16.1935
A-549	CTRP2	2.8429	4.1497	2.8143	14.7631
SW1271	CTRP2	2.9674	4.7156	2.9348	20.6093
COR-L95	CTRP2	2.9958	5.595	2.6374	14.9317
NCI-H2023	CTRP2	2.9987	4.0419	2.9861	13.6706
NCI-H2286	CTRP2	3.0238	4.3227	2.9863	13.5885
NCI-H446	CTRP2	3.0505	4.7135	2.949	13.6328
NCI-H441	CTRP2	3.053	4.9909	2.8855	13.8512
NCI-H1092	CTRP2	3.0691	5.2868	2.8179	14.0482
LCLC-97TM1	CTRP2	3.0831	4.7123	2.9847	13.4052
NCI-H727	CTRP2	3.1003	5.1089	3.0301	19.8524
NCI-H889	CTRP2	3.1111	4.6205	3.0333	13.1461
SW1271	CTRP2	3.1273	4.5567	3.0623	12.9941
Calu-6	CTRP2	3.1328	4.4533	3.1234	19.4287
LC-1/sq-SF	CTRP2	3.153	5.0477	3.0947	19.4605
DMS 454	CTRP2	3.1604	5.0294	2.9924	13.1388
SK-LU-1	CTRP2	3.1798	5.5374	3.0406	19.5627
NCI-H2196	CTRP2	3.2399	5.4378	2.9552	13.0373
NCI-H647	CTRP2	3.257	6.2704	2.6619	14.1032
DMS 273	CTRP2	3.2698	6.3841	2.6288	14.1966
NCI-H1915	CTRP2	3.2882	5.2024	3.0824	12.4262
HCC2108	CTRP2	3.2929	5.189	3.2245	18.563
NCI-H520	CTRP2	3.3093	4.9561	3.1742	12.0299
ChaGo-K-1	CTRP2	3.3758	4.9846	3.2394	11.5921
COLO 668	CTRP2	3.4411	5.7867	3.0478	12.1116
NCI-H2030	CTRP2	3.458	6.8836	2.955	19.0374
Calu-1	CTRP2	3.5287	5.5635	3.4137	17.1552
SK-LU-1	CTRP2	3.531	6.187	2.9843	12.1078
NCI-H1869	CTRP2	3.5427	7.2404	2.5355	13.8506
NCI-H2110	CTRP2	3.5453	6.3521	2.9302	12.2801
DMS 114	CTRP2	3.5685	5.222	3.3819	10.4929
NCI-H23	CTRP2	3.5752	7.0698	2.6456	13.3284
NCI-H2444	CTRP2	3.612	5.407	3.369	10.4121
NCI-H2172	CTRP2	3.6146	4.3783	3.6034	9.563
NCI-H1339	CTRP2	3.6909	5.1516	3.6534	15.806
HCC1195	CTRP2	3.764	5.457	3.688	15.4514
RERF-LC-MS	CTRP2	3.7896	5.8066	3.4115	9.7479
SBC-5	CTRP2	3.8596	5.1155	3.8351	14.6381
NCI-H1395	CTRP2	3.8752	8.7131	2.1633	14.5459
VMRC-LCD	CTRP2	3.9948	6.9699	3.1106	10.4103
IA-LM	CTRP2	4.0979	7.0825	3.1589	9.9634
NCI-H1299	CTRP2	4.1047	5.4522	4.0549	13.0921
NCI-H1373	CTRP2	4.1078	5.3579	3.9222	6.9082
NCI-H2122	CTRP2	4.1224	5.2515	4.0985	12.8852
MOR/CPR	CTRP2	4.1361	5.2739	4.1107	12.7992
NCI-H838	CTRP2	4.2041	6.7563	3.4164	8.6585
NCI-H226	CTRP2	4.2046	5.2256	4.0726	6.0656
HCC1438	CTRP2	4.2493	8.1398	2.7927	11.1159
NCI-H650	CTRP2	4.2848	7.8802	3.4335	14.9197
RERF-LC-Ad2	CTRP2	4.2873	8.7673	2.5196	12.158
NCI-H226	CTRP2	4.2946	5.236	4.2805	11.7047
NCI-H2122	CTRP2	4.3113	5.0008	4.2558	5.0771
KNS-62	CTRP2	4.3575	5.0239	4.3003	4.7756
NCI-H2126	CTRP2	4.3983	6.4754	4.1142	11.984
Lu-65	CTRP2	4.5485	15.1843	-0.4445	22.4781
LK2	CTRP2	4.5628	4.8446	4.5569	3.2284
NCI-H1792	CTRP2	4.6095	6.1245	4.1097	4.8578
NCI-H1793	CTRP2	4.6482	11.9771	1.2426	16.4856
KNS-62	CTRP2	4.823	6.6316	4.5151	9.2579
NCI-H460	CTRP2	4.8453	11.6211	2.203	18.3888
NCI-H460	CTRP2	4.8593	5.39	4.7006	1.8473
NCI-H1792	CTRP2	4.891	8.9349	3.5531	12.9267
NCI-H2023	CTRP2	5.0536	7.8221	3.6632	6.201
Calu-1	CTRP2	5.6083	13.1928	1.4301	13.8873
SW1573	CTRP2	6.0755	8.5072	4.0783	2.4485
LC-1/sq-SF	CTRP2	6.6778	10.5934	3.4843	3.9929
Calu-6	CTRP2	6.7727	9.7445	3.9305	2.2149
NCI-H1339	CTRP2	7.3738	14.1281	2.2664	7.7995
Hs 888.Lu	CTRP2	2.7941	5.0181	2.7156	21.9203
Hs 888.Lu	CTRP2	3.6716	6.626	2.942	11.9017

Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Clivus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
U-CH1	CTRP2	0.6355	4.759	0.3076	30.4687
U-CH1	CTRP2	0.818	4.875	0.6121	35.4624

Cancer Drug Sensitivity Data Curated from 64 Cell Line(s) in Ovary Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
2004	CTRP2	1.8191	2.6705	1.819	28.1499
2004	CTRP2	4.9354	10.6026	2.1739	12.2244
COV434	CTRP2	-0.0742	6.3638	-0.7229	42.1263
COV434	CTRP2	1.1202	3.4972	1.0641	26.3325
SNU-119	CTRP2	1.4346	2.547	1.4345	30.7114
COV644	CTRP2	1.6141	3.2425	1.6104	29.5277
OC 314	CTRP2	1.6385	3.216	1.6261	22.7321
RMG-I	CTRP2	1.7489	3.7864	1.7311	28.6768
FU-OV-1	CTRP2	1.7492	5.393	1.3473	23.3631
RMG-I	CTRP2	1.7605	7.8966	0.4182	26.6039
IGROV-1	CTRP2	1.8804	3.3353	1.8694	21.1158
OVCAR-5	CTRP2	2.0014	4.1287	1.9212	20.5454
COV644	CTRP2	2.0419	4.3533	1.9272	20.3957
SNU-840	CTRP2	2.1341	5.4322	1.9272	26.7577
Caov-3	CTRP2	2.1487	4.1569	2.1233	26.0389
OC 314	CTRP2	2.2007	3.4848	2.1991	25.6125
OVCAR-5	CTRP2	2.2521	3.9308	2.2415	25.3004
SNU-8	CTRP2	2.3234	3.8559	2.3167	24.8123
COV362	CTRP2	2.3391	3.1373	2.3391	24.6851
JHOM-1	CTRP2	2.3592	3.0449	2.3592	24.5516
Caov-3	CTRP2	2.3825	6.1253	1.7862	19.885
JHOC-5	CTRP2	2.387	4.4639	2.3483	24.4965
JHOS-2	CTRP2	2.3982	2.962	2.3982	24.2917
OVTOKO	CTRP2	2.4034	4.9958	2.3003	24.6073
OAW28	CTRP2	2.4051	4.1271	2.3901	24.2956
ONCO-DG-1	CTRP2	2.4057	3.9771	2.397	24.2706
OV7	CTRP2	2.4171	3.0217	2.4171	24.1652
SNU-840	CTRP2	2.4182	5.7701	1.9518	19.1648
A2780	CTRP2	2.468	3.875	2.4455	17.2401
TOV-112D	CTRP2	2.4915	3.1255	2.4915	23.6698
OAW28	CTRP2	2.5227	4.6025	2.3992	17.2249
TOV-21G	CTRP2	2.5655	3.093	2.5655	23.177
EFO-27	CTRP2	2.6057	3.8758	2.6026	22.9194
Kuramochi	CTRP2	2.6874	5.5594	2.5009	23.0069
OAW42	CTRP2	2.7247	3.1575	2.7247	22.1162
OVK18	CTRP2	2.7966	3.5194	2.7966	21.6374
SK-OV-3	CTRP2	2.8215	6.7275	2.3194	23.2461
OV56	CTRP2	2.8907	3.4754	2.8907	21.0106
JHOM-1	CTRP2	2.9061	5.5006	2.572	15.4371
TYK-nu	CTRP2	2.9199	3.9903	2.9183	20.8214
EFO-27	CTRP2	3.0555	5.2379	2.818	14.0885
HEY A8	CTRP2	3.135	4.5529	3.1209	19.4299
JHOS-2	CTRP2	3.2111	6.7593	2.4096	15.2082
COV362	CTRP2	3.2633	5.1686	3.0654	12.5628
OVK18	CTRP2	3.4213	6.0497	2.9244	12.6389
OVCAR-8	CTRP2	3.4742	5.7337	3.3178	17.6637
TOV-112D	CTRP2	3.5079	6.0349	3.022	12.0247
TYK-nu	CTRP2	3.6033	4.3122	3.5959	9.6255
OVSAHO	CTRP2	3.7132	6.4752	3.3708	16.7486
SK-OV-3	CTRP2	3.8436	8.5074	2.2327	14.3393
OVCAR-4	CTRP2	3.9579	4.8244	3.9107	7.4002
OVCAR-8	CTRP2	3.9645	4.762	3.9292	7.3151
HEY A8	CTRP2	4.0776	7.56	2.9118	11.0215
MCAS	CTRP2	4.0891	5.0963	3.9872	6.7226
TOV-21G	CTRP2	4.1821	7.1467	3.2099	9.5543
EFO-21	CTRP2	4.2125	5.2471	4.1937	12.2676
OAW42	CTRP2	4.2499	4.8373	4.2238	5.3819
DOV13	CTRP2	4.2951	5.7257	4.212	11.9397
OVISE	CTRP2	4.4208	4.8915	4.4206	10.8171
ES2	CTRP2	4.4271	4.9115	4.4268	10.7757
EFO-21	CTRP2	4.5657	5.1337	4.4952	3.44
OV7	CTRP2	4.6561	7.9393	3.2619	8.2769
OV56	CTRP2	6.1639	9.1334	3.8407	3.2627
OV-90	CTRP2	7.365	9.7597	4.226	0.8158

Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Thigh Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
P-STS	CTRP2	2.0145	2.9169	2.0145	26.8478
H-STS	CTRP2	2.2354	3.5737	2.2331	25.3837
SYO-1	CTRP2	2.4686	2.9955	2.4686	23.8222
SYO-1	CTRP2	7.4285	8.9949	4.5378	0.1647

Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Soft Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Yamato-SS	CTRP2	2.3832	3.0498	2.3832	24.3912
Aska-SS	CTRP2	2.6298	3.1194	2.6298	22.7487
Yamato-SS	CTRP2	6.5544	8.0664	4.5301	0.4843
Aska-SS	CTRP2	6.6901	8.401	4.459	0.5917
TE 617.T	CTRP2	-1.1503	1.5559	-1.1575	47.9417
TE 617.T	CTRP2	-0.1626	1.7975	-0.1678	34.7073
TE 441.T	CTRP2	0.4217	2.8317	0.4088	37.501
Rh18	CTRP2	1.297	2.1517	1.2969	24.966
Rh41	CTRP2	1.4211	2.1688	1.4211	30.8012
A-204	CTRP2	1.4636	3.5452	1.4213	23.9981
TE 441.T	CTRP2	1.6077	2.9675	1.6029	22.9115
GCT	CTRP2	1.6454	3.5027	1.6156	22.7447
KYM-1	CTRP2	1.8417	2.691	1.8415	21.3376
BT-16	CTRP2	1.8794	3.363	1.8766	27.7574
A-204	CTRP2	2.0627	3.3958	2.061	26.5323
G-401	CTRP2	2.0696	3.047	2.0695	26.4808
RD	CTRP2	2.105	3.1393	2.1048	26.2454
G-401	CTRP2	2.1082	3.7622	2.0783	19.6619
TTC-709	CTRP2	2.1668	3.0121	2.1668	25.8332
Tm87-16	CTRP2	2.1992	3.0959	2.1992	25.6172
GCT	CTRP2	2.2726	3.1286	2.2726	25.1281
KYM-1	CTRP2	2.3256	2.9672	2.3256	24.7749
Hs 729.T	CTRP2	2.3865	2.8664	2.3865	24.3695
G-402	CTRP2	2.4036	3.1986	2.4036	24.2557
BT-12	CTRP2	2.4361	2.7727	2.4361	24.039
SK-LMS-1	CTRP2	2.4892	3.9062	2.4841	23.7023
HT-1080	CTRP2	2.5148	2.937	2.5148	23.5146
SW982	CTRP2	2.576	3.1018	2.576	23.1071
MES-SA	CTRP2	2.6145	2.9524	2.6145	22.8506
RD	CTRP2	2.879	4.9139	2.7155	14.9946
MES-SA	CTRP2	3.0488	4.5417	2.9803	13.529
G-402	CTRP2	3.2151	5.3551	2.9553	13.1098
Hs 729.T	CTRP2	3.4349	5.4286	3.1698	11.67
HT-1080	CTRP2	4.1162	5.7591	3.7752	7.4481
SK-LMS-1	CTRP2	4.5806	8.058	3.1355	8.9651
RKN	CTRP2	5.2097	6.2303	5.0767	6.0355
BT-12	CTRP2	5.7348	7.0615	4.5366	1.1129
BT-16	CTRP2	5.8696	10.2547	3.0909	6.7447
Tm87-16	CTRP2	6.3278	14.0135	1.5793	12.0477
SK-UT-1	CTRP2	6.8455	14.7646	1.5913	11.1604
SW982	CTRP2	6.8959	8.3403	4.5694	0.2544
TTC-709	CTRP2	7.0824	9.894	4.0335	1.5783
RKN	CTRP2	7.1241	8.3378	4.6552	0.0843

Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Pleura Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MPP 89	CTRP2	0.7266	3.5219	0.6883	35.5522
IST-Mes1	CTRP2	1.8145	3.1768	1.8078	21.5404
MSTO-211H	CTRP2	2.2595	4.017	2.2118	18.7147
IST-Mes1	CTRP2	2.3426	3.0702	2.3426	24.662
ACC-MESO-1	CTRP2	2.417	2.9773	2.417	24.1664
NCI-H2452	CTRP2	2.5576	4.4037	2.5315	23.3173
NCI-H2452	CTRP2	2.9021	5.0428	2.7069	14.9551
MPP 89	CTRP2	3.0493	4.76	2.9376	13.6769
JL-1	CTRP2	3.1696	4.5926	3.1545	19.2031
NCI-H2052	CTRP2	3.5156	6.4351	2.8641	12.6183
NCI-H2052	CTRP2	4.773	8.2792	3.7474	12.4243
JL-1	CTRP2	4.9259	8.8357	3.0491	8.6156

Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Prostate Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H660	CTRP2	1.0797	4.2957	0.8966	27.037
VCaP	CTRP2	1.2874	2.5802	1.2854	25.0365
VCaP	CTRP2	1.8772	3.2547	1.8755	27.7681
DU145	CTRP2	2.3276	4.3553	2.2953	24.8703
22Rv1	CTRP2	2.3539	3.251	2.3538	24.5867
LNCaP clone FGC	CTRP2	2.3849	3.4239	2.3845	24.3816
PaCa-3	CTRP2	2.9973	3.6355	2.9973	20.3004
LNCaP clone FGC	CTRP2	3.8169	5.589	3.5247	9.2388
DU145	CTRP2	4.2153	7.6137	3.0169	10.269
PaCa-3	CTRP2	4.442	5.047	4.3863	4.2083

Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Salivary Gland Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
YD-15	CTRP2	1.0876	3.0254	1.0813	33.0438
A-253	CTRP2	2.1704	2.9831	2.1703	25.8095
A-253	CTRP2	3.1361	5.3575	2.8686	13.6632

Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Stomach Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-N87	CTRP2	-3.0823	0.4796	-3.0939	60.5593
NUGC-4	CTRP2	0.5173	4.1858	0.3997	37.1829
23132/87	CTRP2	0.5932	5.9816	0.1124	37.6685
SNU-16	CTRP2	0.9674	2.0154	0.9674	33.8238
OCUM-1	CTRP2	1.0276	4.5699	0.89	50.2098
SNU-16	CTRP2	1.2635	1.9988	1.2635	25.1887
SNU-216	CTRP2	1.3993	3.2308	1.3785	24.3539
ECC10	CTRP2	1.4788	3.6412	1.4276	23.9272
HGC-27	CTRP2	1.5467	3.0138	1.5397	23.3255
SNU-216	CTRP2	1.562	2.9821	1.5607	29.8666
HuG1-N	CTRP2	1.5992	4.2361	1.5415	29.808
KATO III	CTRP2	1.6202	3.6383	1.6055	29.5237
ECC10	CTRP2	1.6527	2.7289	1.6525	29.2587
KATO III	CTRP2	1.8503	3.1698	1.8445	21.2987
IM95	CTRP2	1.878	2.7874	1.878	27.757
HGC-27	CTRP2	1.9456	2.7844	1.9455	27.307
KE-39	CTRP2	2.0149	5.4862	1.7858	27.626
SNU-1	CTRP2	2.0627	4.2457	1.9685	20.1854
SNU-719	CTRP2	2.0803	3.9978	2.0619	26.4709
KE-39	CTRP2	2.1014	8.0211	0.7184	24.5957
MKN1	CTRP2	2.1167	3.7636	2.1088	26.1932
NUGC-3	CTRP2	2.1924	5.9948	1.6289	22.5112
NUGC-3	CTRP2	2.1973	3.809	2.1677	19.0675
SNU-668	CTRP2	2.2272	2.9073	2.2272	25.4304
SNU-1	CTRP2	2.2376	3.5137	2.236	25.3668
Hs 746.T	CTRP2	2.268	2.9181	2.268	25.1591
MKN7	CTRP2	2.336	3.139	2.3359	24.7063
Fu97	CTRP2	2.4869	3.5322	2.4863	23.7024
IM95	CTRP2	2.5307	6.4709	1.8128	19.3648
GSU	CTRP2	2.5401	2.7939	2.5401	23.3458
LMSU	CTRP2	2.5609	3.5494	2.5605	23.2088
SNU-601	CTRP2	2.574	3.0444	2.574	23.1199
MKN74	CTRP2	2.5987	4.7576	2.5415	23.1488
HuG1-N	CTRP2	2.6055	5.3018	2.3083	17.2979
SNU-620	CTRP2	2.6212	3.0987	2.6212	22.806
SH-10-TC	CTRP2	2.8307	3.338	2.8307	21.4098
ECC12	CTRP2	2.9098	4.3682	2.8981	20.9221
Fu97	CTRP2	2.9225	3.8766	2.916	14.1584
Hs 746.T	CTRP2	3.0414	5.0331	2.8616	13.9727
LMSU	CTRP2	3.159	4.7621	3.0564	12.9145
MKN7	CTRP2	3.3653	7.3753	2.2956	15.2564
MKN74	CTRP2	3.5187	5.2522	3.3183	10.8742
SNU-601	CTRP2	4.1085	5.0042	4.0337	6.4954
SH-10-TC	CTRP2	4.365	4.8499	4.3455	4.5926
MKN45	CTRP2	7.6889	8.7435	5.704	0.1023
SNU-1077	CTRP2	2.4813	3.0589	2.4813	23.7378
SNG-M	CTRP2	3.6476	4.278	3.6433	9.32
SNU-685	CTRP2	3.8869	5.869	3.7353	14.8999
SNU-685	CTRP2	4.5104	7.5527	3.3214	8.3432

Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Thyroid Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SW579	CTRP2	2.0398	3.3318	2.0328	20.0403
ML-1 [Human leukemia]	CTRP2	2.1723	5.3957	1.8075	20.4223
SW579	CTRP2	2.2001	3.1615	2.2	25.6116
8305C	CTRP2	2.2041	2.9289	2.2041	25.5847
FTC-238	CTRP2	2.3797	2.8427	2.3797	24.4148
8505C	CTRP2	2.4183	3.8079	2.4142	24.1713
CGTH-W-1	CTRP2	2.4611	3.0118	2.4611	23.8724
TT	CTRP2	2.4767	4.7516	2.4128	23.9845
B-CPAP	CTRP2	2.5042	3.0401	2.5042	23.5855
BHT-101	CTRP2	2.5056	2.9863	2.5056	23.5759
ML-1 [Human leukemia]	CTRP2	2.704	4.16	2.6955	22.2824
TT2609-C02	CTRP2	2.859	4.2685	2.8501	21.2511
FTC-133	CTRP2	3.8675	4.8023	3.8624	14.52
FTC-238	CTRP2	3.927	6.263	3.3634	9.5678
CAL-62	CTRP2	4.175	5.368	4.1413	12.5681
FTC-133	CTRP2	4.354	4.9389	4.3169	4.7271
TT2609-C02	CTRP2	4.665	8.1473	3.1664	8.6569

Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Upper Aerodigestive Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SNU-1214	CTRP2	-0.5276	2.4065	-0.5469	43.8319
CAL-27	CTRP2	-0.0561	2.2543	-0.0624	40.6618
PE/CA-PJ34 (clone C12)	CTRP2	0.2876	1.8844	0.2871	38.3545
BHY	CTRP2	0.5388	3.5074	0.4937	36.8227
PE/CA-PJ49	CTRP2	0.6193	2.2937	0.6181	36.1466
SNU-1076	CTRP2	0.8336	3.4424	0.8045	34.8106
SCC-25	CTRP2	0.8929	2.2092	0.8917	27.662
PE/CA-PJ41 (clone D2)	CTRP2	1.0474	3.8702	0.9959	33.4603
Detroit 562	CTRP2	1.1391	4.4041	1.0334	33.0271
PE/CA-PJ34 (clone C12)	CTRP2	1.2525	3.4911	1.2044	25.4242
HSC-2	CTRP2	1.3912	2.6265	1.391	31.0009
PE/CA-PJ15	CTRP2	1.4142	4.3143	1.3374	31.103
CAL-27	CTRP2	1.4849	3.7569	1.4208	23.9305
HSC-2	CTRP2	1.5609	2.699	1.5597	23.2114
BICR 56	CTRP2	1.6672	4.8347	1.4139	23.3772
BICR 56	CTRP2	1.8545	3.1394	1.8536	27.9169
CAL-33	CTRP2	1.8564	4.1786	1.7576	21.5758
SCC-4	CTRP2	1.8587	3.7293	1.8463	27.9272
CAL-33	CTRP2	1.9148	4.256	1.8715	27.6575
SCC-9	CTRP2	1.9476	4.1344	1.9157	27.4004
SNU-1066	CTRP2	1.9759	4.7782	1.875	27.446
BICR 22	CTRP2	1.9935	5.4236	1.7762	27.7275
BICR 6	CTRP2	2.0528	4.6348	1.9766	26.85
SCC-4	CTRP2	2.0622	4.6102	1.8973	20.4364
BICR 31	CTRP2	2.0992	3.1775	2.0989	26.2846
PE/CA-PJ41 (clone D2)	CTRP2	2.1214	5.1908	1.8133	20.5545
HSC-4	CTRP2	2.1302	4.8748	2.0258	26.4307
BICR 18	CTRP2	2.1681	3.8496	2.1585	25.8567
SNU-46	CTRP2	2.2436	3.8504	2.2356	25.348
FaDu	CTRP2	2.2436	3.0219	2.2436	25.3216
HSC-4	CTRP2	2.2476	4.1815	2.1771	18.872
YD-8	CTRP2	2.2593	3.4376	2.2584	25.2199
PE/CA-PJ15	CTRP2	2.2955	5.3202	1.9649	19.4795
PE/CA-PJ49	CTRP2	2.3203	5.5957	1.9046	19.6268
YD-8	CTRP2	2.4284	3.8125	2.4089	17.4935
BICR 16	CTRP2	2.4317	3.5119	2.4311	24.0703
BICR 31	CTRP2	2.4712	5.49	2.103	18.4505
SCC-9	CTRP2	2.9969	5.9718	2.5024	15.4366
BICR 6	CTRP2	3.0882	5.528	2.7603	14.2053
BICR 16	CTRP2	3.2581	5.7311	2.8722	13.2957
BICR 22	CTRP2	3.6331	6.4104	2.9964	11.787
FaDu	CTRP2	4.0639	8.0679	2.654	12.1096
BICR 18	CTRP2	4.1902	7.674	2.9641	10.5444
SNU-1041	CTRP2	4.8633	11.0417	2.504	17.1932

Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Urinary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
U-BLC1	CTRP2	-1.5997	1.158	-1.6123	44.2953
U-BLC1	CTRP2	-1.3885	1.2691	-1.3937	49.521
SCaBER	CTRP2	0.8675	2.5845	0.8654	34.4962
5637	CTRP2	1.0452	3.1556	1.0347	33.3405
SCaBER	CTRP2	1.1075	2.427	1.1058	26.2337
HT-1376	CTRP2	1.6383	3.8639	1.5704	22.9219
KMBC-2	CTRP2	1.7792	4.0344	1.7475	28.5218
JMSU-1	CTRP2	1.8112	2.5727	1.8112	28.202
BC-3C	CTRP2	1.8643	4.4754	1.711	21.713
HT-1376	CTRP2	2.0137	3.2989	2.0125	26.8568
253J	CTRP2	2.0212	3.4051	2.0191	26.8102
VM-CUB-1	CTRP2	2.1672	5.1631	2.017	26.342
253J-BV	CTRP2	2.2656	3.3146	2.2652	25.1762
TCCSUP	CTRP2	2.33	3.5025	2.329	24.7495
647V	CTRP2	2.358	2.9176	2.358	24.5594
BC-3C	CTRP2	2.461	3.3671	2.4608	23.8739
UM-UC-1	CTRP2	2.4906	3.0042	2.4906	23.6757
HT-1197	CTRP2	2.5593	3.0066	2.5593	23.2181
CAL-29	CTRP2	2.565	4.0866	2.556	23.2101
UM-UC-1	CTRP2	3.2536	4.7521	3.1614	12.2481
HT-1197	CTRP2	3.3106	5.3311	3.0668	12.4167
RT-112	CTRP2	3.5118	4.5592	3.475	10.3355
J82	CTRP2	3.6153	7.918	2.2935	14.6405
UM-UC-3	CTRP2	3.6157	5.3934	3.539	16.4417
647V	CTRP2	3.6531	6.1241	3.1383	11.1783
T24	CTRP2	4.1	6.561	3.4045	8.9623
RT-4	CTRP2	4.1216	6.0004	3.9578	13.3815
KMBC-2	CTRP2	4.1297	11.2771	1.1364	17.9992
UM-UC-3	CTRP2	4.25	5.6847	3.9462	6.4207
639V	CTRP2	4.3355	4.9027	4.3348	11.3873
KU-19-19	CTRP2	4.4041	5.5402	4.3625	11.0694
RT-4	CTRP2	6.4175	10.256	3.4749	4.3691

Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Urogenital System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HeLa	CTRP2	3.8702	4.8924	3.801	8.0618
HeLa	CTRP2	4.9122	5.6047	4.8953	7.6001

References

• [1] URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1797).