Details of the Drug

General Information of Drug (ID: DMCLR6G)

Drug Name
Pegloticase
Synonyms Krystexxa (TN)
Indication
Disease Entry ICD 11 Status REF
Gout FA25 Approved [1]
Affected Organisms
Humans and other mammals
ATC Code
M04AX02: Pegloticase
M04AX: Other antigout preparations
M04A: ANTIGOUT PREPARATIONS
M04: ANTIGOUT PREPARATIONS
M: MUSCULO-SKELETAL SYSTEM
Sequence
TYKKNDEVEFVRTGYGKDMIKVLHIQRDGKYHSIKEVATTVQLTLSSKKDYLHGDNSDVI
PTDTIKNTVNVLAKFKGIKSIETFAVTICEHFLSSFKHVIRAQVYVEEVPWKRFEKNGVK
HVHAFIYTPTGTHFCEVEQIRNGPPVIHSGIKDLKVLKTTQSGFEGFIKDQFTTLPEVKD
RCFATQVYCKWRYHQGRDVDFEATWDTVRSIVLQKFAGPYDKGEYSPSVQKTLYDIQVLT
LGQVPEIEDMEISLPNIHYLNIDMSKMGLINKEEVLLPLDNPYGKITGTVKRKLSSRL
Cross-matching ID
UNII
R581OT55EA
DrugBank ID
DB09208
TTD ID
D06ZIT

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Uric acid (URA) TTZ1SWF NOUNIPROTAC Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7463).
2 Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5.