Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMCLR6G)

Drug Name
Pegloticase Drug Info
Synonyms Krystexxa (TN)
Indication
Disease Entry ICD 11 Status REF
Gout FA25 Approved [1]
Cross-matching ID
TTD Drug ID
DMCLR6G

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
Drug Status:
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Uric acid (URA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pegadricase DMB5JWX Gout FA25 Phase 1 [3]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Uric acid (URA) TTZ1SWF NOUNIPROTAC Modulator [2]

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7463).
2 Mullard A: 2010 FDA drug approvals. Nat Rev Drug Discov. 2011 Feb;10(2):82-5.
3 Uricase formulated with polyethylene glycol (uricase-PEG 20): biochemical rationale and preclinical studies. J Rheumatol. 2002 Sep;29(9):1942-9.