Details of the Drug

General Information of Drug (ID: DMD0YJ5)

Drug Name
BIIB115
Synonyms ION306
Indication
Disease Entry ICD 11 Status REF
Spinal muscular atrophy 8B61 Phase 1 [1]
Drug Type
Antisense oligonucleotide
Cross-matching ID
TTD ID
DUWB31

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
SMN1 messenger RNA (SMN1 mRNA) TTSVGQ5 SMN_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT05575011) A Randomized, Blinded, Placebo-Controlled, Phase 1 Single Ascending Dose Study in Healthy Adult Male Volunteers and an Open-Label Multiple Ascending Dose Study in Pediatric SMA Participants Previously Treated With Onasemnogene Abeparvovec (Zolgensma?) to Evaluate the Safety, Tolerability, and Pharmacokinetics of BIIB115. U.S.National Institutes of Health.
2 Clinical pipeline report, company report or official report of Ionis