Details of the Drug

General Information of Drug (ID: DMD0YJ5)

Drug Name
BIIB115
Synonyms ION306
Indication
Disease Entry ICD 11 Status REF
Spinal muscular atrophy 8B61 Phase 1 [1]
Drug Type
Antisense oligonucleotide
Cross-matching ID
DrugBank ID
DB18418
TTD ID
DUWB31

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
SMN1 messenger RNA (SMN1 mRNA) TTSVGQ5 SMN_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT05575011) A Randomized, Blinded, Placebo-Controlled, Phase 1 Single Ascending Dose Study in Healthy Adult Male Volunteers and an Open-Label Multiple Ascending Dose Study in Pediatric SMA Participants Previously Treated With Onasemnogene Abeparvovec (Zolgensma?) to Evaluate the Safety, Tolerability, and Pharmacokinetics of BIIB115. U.S.National Institutes of Health.
2 Clinical pipeline report, company report or official report of Ionis