Details of the Drug

General Information of Drug (ID: DMDCQW0)

Drug Name
Quinotolast
Synonyms Aslock; Quinotalast; FK-021; FR-71021
Indication
Disease Entry ICD 11 Status REF
Asthma CA23 Phase 3 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 348.32
Logarithm of the Partition Coefficient (xlogp) 1.5
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 6
Chemical Identifiers
Formula
C17H12N6O3
IUPAC Name
4-oxo-1-phenoxy-N-(2H-tetrazol-5-yl)quinolizine-3-carboxamide
Canonical SMILES
C1=CC=C(C=C1)OC2=C3C=CC=CN3C(=O)C(=C2)C(=O)NC4=NNN=N4
InChI
InChI=1S/C17H12N6O3/c24-15(18-17-19-21-22-20-17)12-10-14(26-11-6-2-1-3-7-11)13-8-4-5-9-23(13)16(12)25/h1-10H,(H2,18,19,20,21,22,24)
InChIKey
ZUPLNRDTYQWUHP-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
65871
CAS Number
101193-40-2
TTD ID
D09YDO
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Histamine/peptide leukotriene release (His/p-LT rele) TT7KY5U NOUNIPROTAC Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Studies on structures of urinary metabolites of quinotolast, a new oral anti-allergics. Yakugaku Zasshi. 1993 Aug;113(8):579-85.
2 Effects of quinotolast, a new orally active antiallergic drug, on experimental allergic models. Jpn J Pharmacol. 1993 Sep;63(1):73-81.