Details of the Drug

General Information of Drug (ID: DME0WX2)

Drug Name

Org-43902

Synonyms

LH-ago1; ORG-41247; ORG-42619; ORG-43311; SC-20565; Luteinizing hormone receptor (LHR) agonist, NV Organon; Oral LH agonist, Schering-Plough; Low molecular weight luteinizing hormone (LMW LH) receptor agonist, Merck & Co; Luteinizing hormone agonist (oral), Merck & Co; Luteinizing hormone agonist (oral), Schering-Plough

Indication

Disease Entry	ICD 11	Status	REF
Infertility	GB04	Phase 1	[1]
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Structure

3D Structure is Not Available

3D MOL

2D MOL

Cross-matching ID

TTD ID: D0M3TD

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Luteinizing hormone receptor (LHCGR)	TT2O4W9	LSHR_HUMAN	Agonist	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Infertility

ICD Disease Classification

GB04

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Luteinizing hormone receptor (LHCGR)	DTT	LHCGR	3.55E-01	5.41E-04	4.54E-03

Molecular Expression Atlas (MEA)

MEA Detail

Jump to Detail Molecular Expression Atlas of This Drug

References

1	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800042073)
2	First evidence of ovulation induced by oral LH agonists in healthy female volunteers of reproductive age. J Clin Endocrinol Metab. 2013 Apr;98(4):1558-66.