Details of the Drug

General Information of Drug (ID: DMEC1I9)

Drug Name

Zn2+

Synonyms

zinc ion; Zinc cation; zinc(2+); Zinc, ion (Zn2+); 23713-49-7; Zn(II); Velmanase Alfa; UNII-13S1S8SF37; Zinc (II) ion; zinc(2+) ion; Zinc (II); Velmanase Alfa [INN]; Zn+2; CHEBI:29105; Zn(2+); 13S1S8SF37; 9025-42-7; Microheterogeneityzinc Ion; alpha-Mannanase; Zinc ions; alpha-Mannosidase; Zinc(2+)ions; Mannosidase, alpha-; alpha-Mannopyranosidase; Zinc 2+; Rhlaman; dietary zinc; UNII-M91TG242P2; Zinc dication; zinc(II) cation; Zinc divalent ion; alpha-Mannosidase recombinant human; Recombinant Human Alpha-mannosidase

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]
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Affected Organisms

Humans and other mammals

ATC Code

A16AB15: Zn2+

A16AB: Enzymes

A16A: OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS

A16: OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS

A: ALIMENTARY TRACT AND METABOLISM

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski):
0

Molecular Weight

65.4

Logarithm of the Partition Coefficient

Not Available

Rotatable Bond Count

Hydrogen Bond Donor Count

Hydrogen Bond Acceptor Count

Chemical Identifiers

Formula: Zn+2
IUPAC Name: zinc(2+)
Canonical SMILES: [Zn+2]
InChI: InChI=1S/Zn/q+2
InChIKey: PTFCDOFLOPIGGS-UHFFFAOYSA-N

Cross-matching ID

PubChem CID: 32051
ChEBI ID: CHEBI:29105
CAS Number: 23713-49-7
UNII: J41CSQ7QDS
DrugBank ID: DB01593
TTD ID: D04DWJ

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Mycobacterium CDP-diacylglycerol-inositol phosphatidyltransferase (MycB pssA)	TTI0TCK	PSS_MYCTU	Inhibitor	[2]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 566).
2	Phosphatidylinositol synthesis in mycobacteria. Biochim Biophys Acta. 1999 Jan 4;1436(3):437-50.