Details of the Drug

General Information of Drug (ID: DMEF9JW)

Drug Name
IM0-8400
Indication
Disease Entry ICD 11 Status REF
Diffuse large B-cell lymphoma 2A81 Discontinued in Phase 1/2 [1]
Cross-matching ID
TTD ID
D0H4XV

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Toll-like receptor 7 (TLR7) TTRJ1K4 TLR7_HUMAN Antagonist [2]
Toll-like receptor 8 (TLR8) TT8CWFK TLR8_HUMAN Antagonist [2]
Toll-like receptor 9 (TLR9) TTSHG0T TLR9_HUMAN Antagonist [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Diffuse large B-cell lymphoma
ICD Disease Classification 2A81
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Toll-like receptor 7 (TLR7) DTT TLR7 3.32E-25 0.44 0.88
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 Clinical pipeline report, company report or official report of Idera Pharmaceuticals.
2 Clinical pipeline report, company report or official report of Idera Pharmaceuticals.