Details of the Drug

General Information of Drug (ID: DMF30HL)

• Drug Name: Zarnestra
• Synonyms: JAN; Tipifarnib; Tipifarnib [USAN]; R 115777; R115777; R-11577; R-115777; Tipifarnib (USAN/INN); Zarnestra, IND 58359, R115777, Tipifarnib; (R)-6-(Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone; (R)-R115777; 2 (1H))-Quinolinone,6-(amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-chlorophenyl)-1-methyl-, 2(1H)-quinolinone; 6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2(1H)-one; 6-[(R)-amino-(4-chlorophenyl)-(3-methylimidazol-4-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2-one; 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE

Indication

Disease Entry	ICD 11	Status	REF
Acute myeloid leukaemia	2A60	Phase 3	[1]
Chronic myelogenous leukaemia	2A20.0	Phase 2	[2]
Human papillomavirus infection	1A9Y	Phase 2	[2]
Myelodysplastic syndrome	2A37	Phase 2	[2]
Peripheral T-cell lymphoma	2A90.C	Phase 2	[2]
Colorectal cancer	2B91.Z	Phase 1/2	[3]
Pancreatic cancer	2C10	Phase 1/2	[3]

• Therapeutic Class: Anticancer Agents
• Affected Organisms: Humans and other mammals
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 489.4
  Logarithm of the Partition Coefficient (xlogp); 4.1
  Rotatable Bond Count (rotbonds); 4
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 3
• Chemical Identifiers:
  Formula: C27H22Cl2N4O
  IUPAC Name: 6-[(R)-amino-(4-chlorophenyl)-(3-methylimidazol-4-yl)methyl]-4-(3-chlorophenyl)-1-methylquinolin-2-one
  Canonical SMILES: CN1C=NC=C1[C@@](C2=CC=C(C=C2)Cl)(C3=CC4=C(C=C3)N(C(=O)C=C4C5=CC(=CC=C5)Cl)C)N
  InChI: InChI=1S/C27H22Cl2N4O/c1-32-16-31-15-25(32)27(30,18-6-9-20(28)10-7-18)19-8-11-24-23(13-19)22(14-26(34)33(24)2)17-4-3-5-21(29)12-17/h3-16H,30H2,1-2H3/t27-/m1/s1
  InChIKey: PLHJCIYEEKOWNM-HHHXNRCGSA-N
• Cross-matching ID:
  PubChem CID: 159324
  ChEBI ID: CHEBI:141969
  CAS Number: 192185-72-1
  UNII: MAT637500A
  DrugBank ID: DB04960
  TTD ID: D07NPS
  VARIDT ID: DR00414
• Repurposed Drugs (RPD): Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Farnesyl protein transferase (Ftase)	TTXQKM3	FNTA_HUMAN ; FNTB_HUMAN	Modulator	[4]
Geranyltranstransferase (FDPS)	TTIKWV4	FPPS_HUMAN	Inhibitor	[2]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
ATP-dependent translocase ABCB1 (ABCB1)	OTEJROBO	MDR1_HUMAN	Drug Response	[5]
Granulocyte-macrophage colony-stimulating factor (CSF2)	OT1M7D28	CSF2_HUMAN	Gene/Protein Processing	[6]
GTP-binding protein Rheb (RHEB)	OTFLTSEC	RHEB_HUMAN	Gene/Protein Processing	[7]
GTPase HRas (HRAS)	OTWQN0DP	RASH_HUMAN	Biochemical Pathways	[8]

Molecular Expression Atlas of This Drug

• The Studied Disease: Acute myeloid leukaemia
• ICD Disease Classification: 2A60

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Farnesyl protein transferase (Ftase)	DTT	FNTB; FNTA	5.43E-01	-0.1	-0.4

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Bone Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
RPMI-3460/CS1	GDSC1	3.1953	11.8008	-0.5897	31.9858
EW-18	GDSC1	-1.2394	9.8023	-3.921	55.8345
SK-ES-1	GDSC1	-1.1528	4.3963	-1.7364	59.4108
ES6	GDSC1	-0.7267	4.5243	-1.3106	56.1894
ES4	GDSC1	-0.3589	6.5564	-1.6364	52.5187
ES7	GDSC1	0.2112	12.1135	-3.5265	49.0673
CADO-ES1	CTRP2	0.268	8.2967	-1.3126	36.2149
EW-16	GDSC1	0.4224	6.878	-0.9434	46.8774
ES1	GDSC1	0.7289	6.337	-0.3982	44.0571
A-673	CTRP2	1.1299	11.1496	-1.6697	36.0663
NY	GDSC1	1.2973	6.4749	0.1385	38.9503
NOS-1 [Human HNSCC]	GDSC1	1.2982	3.571	1.1565	34.6115
SK-PN-DW	GDSC1	1.3614	27.7656	-10.1474	47.1964
MHH-ES-1	CTRP2	1.4498	11.3131	-1.4267	32.7754
U2OS	GDSC1	1.5051	10.1039	-1.3179	41.227
HuO-3N1	GDSC1	1.8836	10.3646	-1.0815	38.9555
TC71	CTRP2	1.8939	13.1198	-1.8467	32.4938
ES8	GDSC1	1.9684	5.7295	1.1528	30.449
HOS	GDSC1	2.0063	4.956	1.5048	28.1566
MG-63	GDSC1	2.1979	4.3475	1.9285	24.3042
MHH-ES-1	GDSC1	2.2322	10.8036	-0.9679	37.1026
CAL-72	GDSC1	2.3818	6.1059	1.4142	26.6419
EW-13	GDSC1	2.545	14.8608	-2.686	39.2699
SJSA-1	GDSC1	2.8444	13.1321	-1.5615	36.0325
A-673	GDSC1	3.0401	5.2497	2.4659	16.0818
SaOS-2	GDSC1	3.0737	11.5014	-0.5481	32.3318
CAL-78	GDSC1	3.1561	9.8635	0.3383	28.5921
EW-1	GDSC1	3.1831	11.8169	-0.6085	32.0954
G-292 clone A141B1	GDSC1	3.3735	4.1124	3.2826	8.4373
ES5	GDSC1	3.4491	10.9374	0.0621	28.5733
EW-7	GDSC1	3.7111	13.0579	-0.7719	30.6544
SK-N-MC	CTRP2	3.8811	11.3108	0.8957	19.4496
TC-71	GDSC1	4.2798	5.6907	3.375	4.0041
EW-3	GDSC1	4.4011	8.3766	2.1363	13.0921
SaOS-2	CTRP2	4.5019	6.3199	3.9127	5.919
MHH-ES-1	CTRP2	4.5337	6.6543	3.7823	6.3804
EW-24	GDSC1	4.5417	6.074	3.3723	3.2981
Hs 888.T	CTRP2	4.5556	10.0056	2.1456	13.1147
HuO9	GDSC1	4.6173	7.0933	2.9327	6.4209
EW-11	GDSC1	4.6413	9.4919	1.7685	14.8639
Hs 822.T	CTRP2	4.7074	5.1177	4.6542	2.4349
HOS	CTRP2	4.7784	7.7306	3.4736	7.1346
U2OS	CTRP1	4.7894	10.1124	2.3042	23.8804
CHSA0108	GDSC1	5.2291	13.7861	0.0897	22.3135
CAL-78	CTRP2	5.2932	13.4835	1.0303	15.9876
SJSA-1	CTRP2	5.5356	7.5507	4.1733	2.8153
CAL-78	CTRP2	5.5757	10.0558	2.9666	7.754
G-292 clone A141B1	CTRP2	5.6071	19.7356	-1.8377	24.2172
SJSA-1	CTRP2	5.8961	16.8284	-0.1537	18.9202
CHSA8926	GDSC1	5.9878	14.2735	0.4109	18.6456
U2OS	CTRP2; CTRP1	6.48	21.9138	-2.2155	23.621
SW1353	CTRP2	6.5662	10.2688	3.5654	3.8196
SW1353	CTRP2	6.8945	17.2766	0.3934	15.3807
MG-63	CTRP2	7.0208	12.1467	2.9744	5.5333
CHSA0011	GDSC1	7.0269	9.4689	3.1938	0.8825
H-EMC-SS	GDSC1	7.9931	21.6589	-1.7638	22.3162

Cancer Drug Sensitivity Data Curated from 386 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JK1	CTRP2	-0.8541	4.5918	-1.2751	52.8716
MEC1	CTRP2	1.3358	13.6588	-2.6419	35.583
JK1	CTRP2	3.4683	7.4089	2.3839	14.6434
JM1	CTRP2	1.7392	7.5584	0.5376	26.2613
JM1	GDSC1	2.3142	11.7554	-1.3589	37.6718
MOLP-8	CTRP2	-7.8113	17.3151	-13.5368	61.1128
KMS-26	CTRP2	-6.2656	-1.6711	-6.2843	73.2192
A4/Fukuda	GDSC1	-5.4607	6.3378	-7.046	72.6225
RPMI-8402	CTRP2	-5.4316	8.9707	-7.6582	60.1096
SIG-M5	GDSC1	-5.4001	1.2973	-5.6672	83.0501
A4/Fukuda	CTRP2	-5.3797	1.2939	-5.5699	66.0513
QIMR-WIL	GDSC1	-5.1563	1.0208	-5.3648	83.4584
JVM-3	CTRP2	-4.1846	4.1998	-4.81	58.6023
ML-2	GDSC1	-4.1806	6.8644	-5.8464	68.8343
SEM	CTRP2	-4.0936	8.2178	-5.9449	56.3324
NALM-6	GDSC1	-4.0522	3.3807	-4.6265	74.7566
NB4	GDSC1	-3.9075	5.2047	-4.9864	70.6667
EoL-1	CTRP2	-3.8143	1.2906	-3.9147	58.2971
RPMI-6666	GDSC1	-3.8114	23.9889	-13.0698	57.4142
Reh	GDSC1	-3.6902	17.1589	-9.7271	59.467
MOLP-8	GDSC1	-3.6703	7.5253	-5.542	66.5247
MV4-11	CTRP2	-3.408	1.6419	-3.5214	55.8354
NB4	CTRP2	-3.3825	1.349	-3.4669	55.7659
Peer	CTRP2	-3.2852	2.2505	-3.4634	54.953
MOLM-16	CTRP2; CTRP1	-3.2667	-0.1175	-3.2752	73.7158
HPB-ALL	CTRP2	-3.1995	12.541	-6.7118	59.0186
KMS-12-BM	CTRP2	-3.0401	6.0353	-4.0677	63.3616
NALM-6	CTRP2	-3.0074	3.8106	-3.4393	53.0444
Reh	CTRP2	-2.7582	3.1495	-3.0383	51.7523
BC-1	GDSC1	-2.7455	4.1788	-3.4111	68.4591
DoHH2	CTRP2	-2.7035	0.289	-2.7127	51.6046
SKM-1	CTRP2; CTRP1	-2.7025	2.0538	-2.8193	51.5574
Pfeiffer	CTRP2	-2.5996	8.5848	-4.4752	50.5807
Ku812	GDSC1	-2.4899	7.6658	-4.3367	62.435
SU-DHL-8	CTRP2	-2.4423	4.5729	-3.0023	62.3462
OCI-Ly3	CTRP2	-2.4357	3.905	-2.8384	49.8566
PF-382	CTRP2	-2.3951	7.3085	-3.7887	49.6978
MOLT-16	CTRP2	-2.3808	2.6331	-2.5506	64.3111
MOLT-3	CTRP2	-2.3281	2.6731	-2.4999	49.1799
BCP-1	CTRP2	-2.2831	4.0478	-2.7039	48.98
JSC-1	GDSC1	-2.1995	12.5073	-6.1043	57.914
THP-1	CTRP2; CTRP1	-2.1668	6.2085	-3.1682	51.1042
SUP-M2	CTRP2	-2.146	4.2376	-2.598	48.1984
GDM-1	CTRP2; CTRP1	-2.0759	4.9145	-2.6886	47.9211
Ki-JK	CTRP2	-2.0624	4.9971	-2.6986	47.8156
MOLT-16	GDSC1	-1.8757	2.4828	-2.0709	67.3898
P30/OHK	GDSC1	-1.8514	7.7868	-3.7079	59.7583
OCI-AML-2	CTRP2	-1.8092	4.9107	-2.3991	46.3508
HH [Human lymphoma]	GDSC1	-1.7922	13.0812	-5.9565	56.3986
OCI-AML-3	CTRP1	-1.7566	5.5947	-2.532	71.3929
697	CTRP2	-1.7394	2.9594	-1.9115	45.4786
SU-DHL-6	CTRP2	-1.7331	2.4413	-1.8374	60.2708
GDM-1	GDSC1	-1.6409	4.8495	-2.4073	61.8935
MOLT-13	CTRP2	-1.5523	5.5993	-2.3137	45.0561
SIG-M5	CTRP2	-1.4988	2.3437	-1.5799	43.7735
BV-173	CTRP2	-1.44	3.8591	-1.7474	43.7948
Karpas-299	CTRP2	-1.4171	12.4416	-4.8304	46.2972
SU-DHL-6	GDSC1	-1.4117	3.1501	-1.6975	62.9362
HEL	GDSC1	-1.2883	5.8094	-2.3499	58.7844
ALL-PO	GDSC1	-1.1905	3.542	-1.5464	60.7341
KO52	CTRP2	-1.1302	3.5867	-1.3594	41.6886
OCI-Ly19	GDSC1	-1.0681	5.6387	-2.0515	57.6273
SUP-T1	CTRP2	-1.0497	9.6556	-3.2554	43.9423
SU-DHL-8	GDSC1	-0.9904	8.5374	-3.1163	55.3179
GA-10	CTRP2	-0.9896	5.4407	-1.653	41.6472
MV4-11	GDSC1	-0.9491	5.4402	-1.8532	57.0372
SU-DHL-5	GDSC1	-0.9346	3.8029	-1.3327	58.4598
ALL-SIL	GDSC1	-0.9077	4.6444	-1.5448	57.4346
Karpas-620	GDSC1	-0.8615	7.4683	-2.5346	55.1896
MOLM-13	CTRP2	-0.6362	6.7418	-1.6894	40.2785
RPMI-8402	GDSC1	-0.6154	9.0829	-2.9651	53.2607
RPMI-8226	CTRP2; CTRP1	-0.5721	6.3017	-1.4657	39.6546
NKM-1	GDSC1	-0.5546	4.4962	-1.1145	54.8508
Karpas-231	GDSC1	-0.5533	5.6791	-1.5111	54.1935
A3/Kawakami	GDSC1	-0.5294	8.0452	-2.4278	53.1191
BL-70	CTRP1	-0.5143	4.9132	-0.9841	67.4099
Kasumi-2	CTRP2	-0.5092	7.3429	-1.7694	39.9334
SUP-T1	GDSC1	-0.4903	10.6579	-3.5438	52.2965
MOLM-6	CTRP2	-0.4892	6.6542	-1.4999	50.1787
EB1	CTRP2	-0.4588	7.541	-1.7894	39.7789
SU-DHL-5	CTRP1	-0.4447	3.4808	-0.6017	70.5913
U-937	CTRP2; CTRP1	-0.4094	2.9403	-0.4916	39.248
KMS-26	CTRP2	-0.3248	1.9601	-0.3366	35.8093
Jurkat	CTRP2	-0.307	5.3513	-0.8824	37.2767
NU-DUL-1	CTRP2; CTRP1	-0.2353	5.7251	-0.9135	48.4798
TUR	GDSC1	-0.2107	3.5768	-0.487	52.1622
PL21	CTRP2; CTRP1	-0.1632	6.4815	-1.0835	37.2795
KMS-34	CTRP2	-0.1292	6.0195	-0.8952	47.7294
Kasumi-1	CTRP2	-0.0838	10.0538	-2.417	39.4961
SUP-B15	GDSC1	-0.0799	6.7979	-1.438	50.5632
697	GDSC1	-0.062	6.9408	-1.4774	50.4309
HC-1	GDSC1	-0.0575	8.442	-2.1116	50.3417
OCI-AML-2	GDSC1	-0.041	5.9823	-1.0746	50.3188
DEL	GDSC1	-0.0288	7.5193	-1.684	50.1889
SUP-HD1	CTRP2	0.0071	7.8233	-1.4004	37.3142
TK [Human B-cell lymphoma]	GDSC1	0.0138	9.2775	-2.4102	49.9239
Daudi	CTRP2	0.0276	5.7077	-0.6251	35.3764
SU-DHL-1	CTRP2	0.0326	5.5189	-0.5617	35.186
JURL-MK1	CTRP2	0.0454	5.7721	-0.6259	35.315
NCO2	CTRP2	0.0652	5.9145	-0.6498	35.3083
NU-DHL-1	CTRP2	0.0752	8.1413	-1.4537	37.1874
KMS-21-BM	CTRP2	0.0876	8.2245	-1.4739	37.1866
ST486	GDSC1	0.0923	8.3112	-1.9005	49.4357
KMS-11	CTRP2; CTRP1	0.0975	9.5308	-1.9994	38.2254
SUP-T11	CTRP2	0.1008	7.4932	-1.1727	46.5668
SU-DHL-16	GDSC1	0.1187	3.3422	-0.076	48.6987
OCI-AML-3	CTRP2; CTRP1	0.1404	6.402	-0.7275	35.304
SU-DHL-10	CTRP2	0.1863	2.0649	0.1805	44.1444
JVM-2	CTRP2	0.3055	12.8574	-3.2778	39.5166
Hs 445	GDSC1	0.3151	19.6869	-7.0924	49.1217
YT	GDSC1	0.3739	7.4376	-1.2309	47.4192
CML-T1	CTRP2	0.4476	8.7193	-1.2977	35.5762
RS4;11	CTRP2	0.5046	10.253	-1.8986	36.6538
PF-382	GDSC1	0.5089	9.8906	-2.1932	47.2233
CA46	CTRP2	0.5149	7.6072	-0.7758	34.0818
CCRF-CEM	GDSC1	0.5338	7.4	-1.0493	46.2366
Granta-519	CTRP2	0.5419	9.4988	-1.5309	35.781
OCI-Ly19	CTRP2	0.6594	5.8969	0.0016	31.3721
CESS	GDSC1	0.67	23.4584	-8.6268	48.4051
P12-Ichikawa	CTRP2	0.6745	8.1093	-0.8079	33.6367
SR	GDSC1	0.6784	7.1855	-0.8073	45.0238
HuNS1	CTRP2	0.7067	12.2429	-2.5949	37.2923
BL-41	GDSC1	0.7465	4.3419	0.3504	42.1993
ALL-SIL	CTRP2	0.7831	7.7335	-0.5413	32.5664
RS4;11	GDSC1	0.7949	8.867	-1.437	45.0833
LC4-1	GDSC1	0.7958	11.126	-2.4904	46.0146
M-07e	CTRP2	0.8012	6.2021	0.0527	30.7474
KE-37	CTRP2	0.82	10.9442	-1.8873	35.6469
KE-37	GDSC1	0.8294	7.8162	-0.928	44.2444
HH [Human lymphoma]	CTRP2	0.8366	11.9651	-2.3374	36.4572
EB2	GDSC1	0.8715	6.7494	-0.4209	43.1329
KE-97	CTRP2; CTRP1	0.9058	5.9441	0.2571	29.82
DEL	CTRP2	1.0022	3.7994	0.9001	27.275
MOLT-4	GDSC1	1.0159	7.0537	-0.4018	42.16
Ri-1	CTRP2	1.0577	7.5301	-0.1694	39.9996
MY-M12	GDSC1	1.1022	7.4743	-0.498	41.8278
TALL-1 [Human adult T-ALL]	CTRP2	1.1169	17.9458	-4.9138	45.0767
CA46	GDSC1	1.1512	9.0294	-1.1569	42.76
BV-173	GDSC1	1.1729	5.0227	0.5854	38.202
Daudi	GDSC1	1.1776	6.7573	-0.1067	40.4264
L-540	CTRP2	1.2046	5.5269	0.7129	36.7862
VL51	GDSC1	1.2206	11.7956	-2.4018	44.028
ST486	CTRP2	1.2258	9.9238	-1.0172	32.4397
MOLM-13	GDSC1	1.2392	6.8467	-0.0817	39.9696
Ku812	CTRP2; CTRP1	1.2437	7.3667	0.0977	29.2667
HT	CTRP2; CTRP1	1.273	5.3193	0.8533	26.6467
ATN-1	GDSC1	1.289	3.0847	1.2318	34.2355
CTV-1	GDSC1	1.3616	5.4103	0.642	36.6919
RCH-ACV	CTRP2	1.3617	9.258	-0.5826	39.4637
MEG-01	GDSC1	1.3753	7.8713	-0.4002	39.9883
JURL-MK1	GDSC1	1.3951	8.4781	-0.6594	40.487
HT	GDSC1	1.4011	7.988	-0.4277	39.909
SET-2	CTRP2	1.412	7.9756	0.0214	28.9297
HL-60	CTRP2	1.4387	11.2886	-1.4264	32.8067
GR-ST	GDSC1	1.4492	7.6137	-0.2088	39.0579
KYO-1	CTRP2	1.4783	6.5661	0.6522	35.6455
ME1	CTRP2	1.4819	5.6831	0.9651	25.5396
HDLM-2	CTRP2	1.4865	10.0709	-0.8197	31.1506
HL-60	GDSC1	1.4901	7.1497	0.0416	38.0727
Namalwa	CTRP2	1.4948	7.5995	0.2639	27.902
DoHH2	CTRP2	1.5048	10.4938	-0.9941	31.5542
VAL	GDSC1	1.5061	13.2992	-2.8623	43.3304
SUP-HD1	GDSC1	1.5379	6.0378	0.574	35.8446
BC-3	GDSC1	1.5393	6.8683	0.2168	37.1957
P32/ISH	GDSC1	1.5494	3.9219	1.3466	31.8806
BE-13	GDSC1	1.5658	11.6815	-2.0193	42.0583
Mono-Mac-6	GDSC1	1.5779	5.0869	0.9968	33.6383
MV4-11	CTRP2	1.5984	3.3331	1.5786	23.0239
RPMI-8402	CTRP2	1.6055	4.9303	1.322	23.8943
KG-1	GDSC1	1.6329	6.8197	0.3339	36.2139
EoL-1	GDSC1	1.6442	4.1899	1.3748	31.1184
KMOE-2	GDSC1	1.6481	6.142	0.6446	34.8656
Sc-1	GDSC1	1.6588	8.7281	-0.5162	38.7223
MHH-PREB-1	GDSC1	1.6881	3.3022	1.6275	29.281
KMS-20	CTRP2	1.7038	8.8001	-0.0306	28.227
Karpas-45	GDSC1	1.7062	9.5229	-0.8467	39.2835
H9	GDSC1	1.7194	7.5444	0.0941	36.5729
HuT 78	CTRP2	1.7228	8.5064	0.1175	27.7025
Mino	CTRP2	1.7375	6.6947	0.8809	25.0701
DB	CTRP2	1.7437	4.8344	1.4973	22.8441
KMS-12-BM	CTRP2	1.7767	4.7743	1.5482	22.5613
P3HR-1	CTRP2; CTRP1	1.7786	5.8146	1.2474	32.0929
JeKo-1	CTRP2	1.7848	9.2648	-0.1546	28.3766
Karpas-422	CTRP2	1.7941	12.9611	-1.8668	32.8063
LAMA-84	CTRP2	1.7959	5.4863	1.3693	23.1427
SUP-M2	GDSC1	1.8092	3.8133	1.6574	28.3534
Mono-Mac-1	CTRP2	1.8317	9.2925	-0.1195	36.3393
MC116	GDSC1	1.8659	4.9999	1.338	29.99
NK-92MI	GDSC1	1.8913	9.3639	-0.5926	37.7331
NCI-H929	CTRP2	1.8914	11.9494	-1.2916	31.2101
KMS-28BM	CTRP2	1.8958	14.3541	-2.4386	40.465
CMK	CTRP2	1.9469	5.7729	1.4403	22.4334
MJ	CTRP2	1.9483	10.2226	-0.4269	28.7275
U-698-M	GDSC1	1.9621	6.9735	0.5982	33.2389
OCI-AML-5	GDSC1	2.0019	6.8291	0.7039	32.5377
SKM-1	CTRP2; CTRP1	2.0586	4.8183	1.847	20.7024
WIL2 NS	GDSC1	2.0609	19.4283	-5.3843	43.651
L-540	GDSC1	2.0711	5.6937	1.2749	29.1704
DND-41	GDSC1	2.0765	8.1162	0.1802	34.3256
SK-MM-2	CTRP2	2.0773	18.7496	-4.4147	36.4773
KHM-1B	CTRP2	2.0833	12.2677	-1.2571	30.6036
P31/FUJ	CTRP2	2.0965	11.2683	-0.7698	29.2902
JJN-3	CTRP2	2.1043	11.4761	-0.8604	29.5162
K-562	CTRP2	2.11	7.2711	1.0453	23.4034
Jiyoye	GDSC1	2.1259	8.3552	0.1149	34.3136
SU-DHL-8	CTRP2	2.2163	4.5652	2.0744	19.3297
F-36P	CTRP2	2.223	5.8101	1.7267	20.5686
GDM-1	CTRP2; CTRP1	2.2295	5.3919	1.8741	20.0849
PL-21	GDSC1	2.2502	11.0864	-1.0895	37.3214
WSU-NHL	GDSC1	2.2613	8.8033	0.0306	33.9411
JJN-3	GDSC1	2.3318	6.935	0.9849	29.3565
KCL-22	GDSC1	2.3319	4.559	2.0012	23.0616
NOMO-1	CTRP2; CTRP1	2.371	14.2371	-1.9258	31.4752
MOLM-16	CTRP2; CTRP1	2.3792	5.3301	2.0561	18.9742
K-562	GDSC1	2.4019	4.9373	1.9335	23.1425
KM-H2	CTRP2	2.4202	13.1475	-1.3586	29.9712
SU-DHL-1	GDSC1	2.4715	4.5702	2.1477	21.2872
LAMA-84	GDSC1	2.4745	9.4156	-0.0646	33.261
Farage	GDSC1	2.491	6.2655	1.4521	25.8377
HEL	CTRP2	2.4911	6.1088	1.9089	19.1148
KOPN-8	GDSC1	2.5012	7.5317	0.8697	29.0855
Ki-JK	CTRP2	2.5024	5.1272	2.2472	17.8303
BV-173	CTRP2	2.5115	5.5146	2.1388	18.1992
KMS-27	CTRP2	2.5235	16.7382	-3.0166	33.2463
NU-DUL-1	CTRP2; CTRP1	2.5734	4.1573	2.5289	16.6932
TF-1	CTRP2	2.5915	5.286	2.2978	17.378
A3/Kawakami	CTRP2	2.6047	6.2291	1.9852	18.5043
BALL-1	GDSC1	2.611	8.1375	0.6841	29.4663
PL21	CTRP2; CTRP1	2.6207	5.5033	2.2646	17.4923
CTB-1	GDSC1	2.6753	10.6722	-0.4955	33.8203
NU-DUL-1	GDSC1	2.6767	7.6666	0.9737	27.6731
OCI-AML-3	GDSC1	2.6872	8.4574	0.6009	29.4971
L-428	CTRP2	2.6908	13.2808	-1.1688	28.801
KMS-34	CTRP2	2.6968	4.2938	2.6415	15.8278
EM-2	GDSC1	2.7334	5.7385	1.9355	21.4128
KMS-12-BM	GDSC1	2.7347	11.9412	-1.0688	35.239
DoHH2	GDSC1	2.7375	4.9133	2.2978	18.8185
HAL-01	GDSC1	2.7477	8.93	0.4269	30.0095
NB4	CTRP2	2.7484	4.4214	2.6772	15.539
SUP-B15	CTRP2	2.7549	11.5556	-0.2722	26.1063
Peer	CTRP2	2.8164	4.9986	2.6253	15.5105
LP-1	CTRP1	2.8447	17.4155	-3.0495	45.2761
Reh	CTRP2	2.8518	4.8477	2.7022	15.1263
Mono-Mac-6	CTRP2	2.8697	7.3327	1.8092	18.4523
MC116	CTRP2; CTRP1	2.8859	4.5716	2.8005	20.1085
PF-382	CTRP2	2.9026	5.6678	2.5113	15.6731
HPB-ALL	CTRP2	2.9167	5.892	2.4461	15.8772
WSU-DLCL2	CTRP2; CTRP1	2.922	9.4303	0.9104	21.7795
MOLT-13	CTRP2	2.9459	5.0838	2.7434	14.69
Ri-1	CTRP2	2.9522	6.8645	2.0958	17.1225
BL-70	CTRP1	3.029	4.2161	3.0044	29.173
Namalwa	GDSC1	3.0372	6.4591	1.8983	20.2149
EHEB	CTRP2	3.0456	10.0235	0.7415	22.0055
DND-41	CTRP2	3.0481	10.8808	0.3319	23.4217
L-428	GDSC1	3.0483	16.4435	-3.0316	38.151
KMS-11	CTRP2; CTRP1	3.0596	9.1666	1.1692	20.4776
RPMI-8226	GDSC1	3.0598	5.3806	2.4266	16.2777
DB	GDSC1	3.1434	7.4961	1.4952	22.4285
SU-DHL-6	CTRP2	3.1467	5.4635	2.8454	13.7178
THP-1	CTRP2; CTRP1	3.1486	6.1387	2.6047	14.7036
MOLT-16	CTRP2	3.1623	4.8033	3.0508	12.924
Ku812	CTRP1	3.1888	4.2401	3.1699	26.8498
OCI-M1	GDSC1	3.1955	6.674	1.945	19.1677
OCI-AML-2	CTRP2	3.1967	4.8612	3.0748	12.7319
KMS-18	CTRP2	3.2029	11.2017	0.3227	29.7651
RL	CTRP2	3.2772	5.2921	3.0429	12.6036
SUP-T1	CTRP2	3.289	5.5557	2.9682	12.8459
KE-97	CTRP1	3.297	4.6151	3.2366	25.6086
P12-Ichikawa	GDSC1	3.2975	9.234	0.7768	25.8897
SU-DHL-4	GDSC1	3.3019	4.7258	2.9653	11.0998
OPM-2	CTRP2	3.3286	14.3396	-1.1006	27.071
Hs 611.T	CTRP2	3.3635	11.4525	0.3505	22.5856
IM-9	GDSC1	3.3741	5.2128	2.8167	11.8759
NCI-H929	CTRP2	3.3788	6.5189	2.6862	13.6795
Karpas-299	CTRP2	3.3864	6.2731	2.797	13.227
MHH-CALL-4	CTRP2	3.3878	9.5878	1.2783	25.4611
RPMI-8226	CTRP2; CTRP1	3.3921	7.0394	2.4796	14.5388
SUP-T11	CTRP2	3.4797	5.8141	3.0786	11.8855
Granta-519	GDSC1	3.5221	9.7734	0.706	25.3205
MOTN-1	CTRP2	3.5658	8.5829	1.9304	16.2131
Mono-Mac-1	CTRP2	3.5798	6.109	3.0676	11.6516
LP-1	GDSC1	3.5914	6.1512	2.5674	12.8489
TALL-1 [Human adult T-ALL]	CTRP2	3.638	6.4683	2.9765	11.8529
L-1236	CTRP2	3.6464	7.4168	2.5581	14.4603
Raji	CTRP2	3.6479	6.6042	2.9273	12.0212
MOLM-6	CTRP2	3.6685	6.2949	3.0826	11.3548
SU-DHL-1	CTRP2	3.6731	5.3183	3.465	9.8768
AMO1	GDSC1	3.6738	12.9356	-0.7425	30.6918
Raji	GDSC1	3.6921	8.3296	1.5736	19.6006
KMS-27	CTRP2	3.6922	5.9257	3.2607	10.5976
MN-60	GDSC1	3.6954	11.4941	-0.0038	27.8918
U266B1	CTRP2	3.705	8.9197	1.9022	15.9929
HT	CTRP2; CTRP1	3.7451	5.1851	3.5888	9.2953
JVM-2	GDSC1	3.7548	5.6527	2.9614	9.1236
SU-DHL-5	CTRP1	3.7608	5.3021	3.5691	20.0033
SR	CTRP2	3.7788	6.4484	3.13	10.8779
L-363	GDSC1	3.795	11.1596	0.248	26.4354
SK-MM-2	GDSC1	3.8108	17.8907	-3.1037	35.9717
EM-2	CTRP2	3.8132	5.6938	3.4808	9.4166
CML-T1	CTRP2	3.8362	6.3979	3.211	10.4074
L-1236	GDSC1	3.8645	5.557	3.1059	7.5574
HEL	CTRP2	3.8655	5.1785	3.7188	8.3726
RC-K8	GDSC1	3.8656	4.9174	3.425	5.0465
WSU-DLCL2	CTRP2; CTRP1	3.8703	6.1401	3.3637	9.8012
P3HR-1	CTRP2; CTRP1	3.8802	5.8396	3.499	9.248
HEL 92.1.7	CTRP2	3.8817	9.3263	1.8712	15.7043
HDLM-2	CTRP2	3.9243	7.9258	2.5895	12.6998
MHH-CALL-3	CTRP2	3.9293	17.5849	-2.1778	28.375
P31/FUJ	CTRP2	3.9331	6.5819	3.2275	10.0932
U-937	CTRP2; CTRP1	3.9426	6.4687	3.2943	9.8871
ME1	CTRP2	3.9481	5.6406	3.6451	8.4114
RPMI-6666	CTRP2	3.964	14.7227	-0.7222	24.5647
RPMI-8866	GDSC1	3.9836	5.4989	3.2369	6.0782
SU-DHL-10	CTRP2	4.0394	6.3218	3.4522	8.9242
Mono-Mac-6	CTRP2	4.0425	14.0994	-0.3429	29.1889
Ramos.2G6.4C10	GDSC1	4.0635	9.0318	1.5368	18.4097
EJM	CTRP2; CTRP1	4.0662	9.1242	2.1495	14.2422
KCL-22	CTRP2	4.0982	9.522	1.9753	14.796
U266B1	GDSC1	4.1015	9.5791	1.2946	19.7864
RCH-ACV	CTRP2	4.131	6.0102	3.6835	7.7688
Karpas-422	GDSC1	4.1375	15.3731	-1.5724	31.6041
WSU-DLCL2	GDSC1	4.1497	5.6423	3.3	5.0013
L-1236	CTRP2	4.1584	7.2924	3.1175	9.9886
RS4;11	CTRP2	4.1612	7.1721	3.1777	9.7355
MC116	CTRP2; CTRP1	4.164	5.3602	3.9861	6.5962
P12-Ichikawa	CTRP2	4.1816	6.0062	3.7372	7.424
MOLM-13	CTRP2	4.2042	6.1089	3.7148	7.4546
AMO1	CTRP2; CTRP1	4.2107	7.4493	3.0998	13.6462
EJM	GDSC1	4.2184	7.5879	2.3847	11.8801
JURL-MK1	CTRP2	4.2374	5.9135	3.8351	6.891
MLMA	GDSC1	4.2397	10.34	1.0275	20.8497
MM1.S	CTRP2	4.2538	14.8351	-0.5245	24.6227
ROS-50	GDSC1	4.2582	7.2602	2.5798	10.2596
EHEB	GDSC1	4.2592	16.3484	-1.9595	32.2321
NOMO-1	CTRP2; CTRP1	4.3082	7.5065	3.1644	9.5313
KMS-18	CTRP2	4.3224	6.4787	3.6628	7.3695
OCI-M1	CTRP2	4.337	6.0487	3.8762	6.4714
L-363	CTRP2	4.37	8.9761	2.4916	12.0922
KM-H2	CTRP2	4.3806	6.1526	3.8722	6.3783
LAMA-84	CTRP2	4.3929	6.2269	3.85	6.438
L-540	CTRP2	4.418	5.8583	4.0441	5.5939
EJM	CTRP1	4.4953	12.9683	0.6252	32.8478
MHH-CALL-4	CTRP2	4.5123	6.5347	3.8199	6.2753
EHEB	CTRP2	4.5175	7.4117	3.3973	8.0121
SU-DHL-4	CTRP2; CTRP1	4.538	9.886	2.1986	17.4981
OCI-Ly10	CTRP1	4.5892	13.2754	0.5529	32.696
DEL	CTRP2	4.6099	5.1499	4.5377	3.1526
REC-1	CTRP2	4.6678	6.9384	3.7677	6.1403
SR	CTRP2	4.6868	7.3776	3.5679	6.9327
SU-DHL-4	CTRP2; CTRP1	4.7003	5.81	4.3545	3.7307
JVM-3	GDSC1	4.7102	6.3616	3.3456	3.0849
L-363	CTRP2	4.7286	11.2764	1.6614	14.6986
Raji	CTRP2	4.733	5.4766	4.5346	2.8309
KCL-22	CTRP2	4.753	6.2711	4.174	4.2628
MM1.S	CTRP2	4.8455	7.3172	3.7383	5.8863
KYO-1	CTRP2	4.8559	6.7777	4.0161	4.7005
SK-MM-2	CTRP2	4.8618	6.1218	4.3469	3.3046
HD-MY-Z	CTRP2	4.8711	10.7221	2.0598	12.8164
Ci-1	CTRP2	4.8916	5.4864	4.686	1.8298
RL	GDSC1	5.0076	6.8336	3.3087	2.705
AMO1	CTRP2; CTRP1	5.0192	7.726	3.6921	5.8164
LP-1	CTRP2; CTRP1	5.033	17.7315	-1.299	23.9799
REC-1	CTRP2	5.0804	10.3892	2.4019	14.8223
DG-75	GDSC1	5.0934	7.8843	2.876	5.5866
Karpas-299	GDSC1	5.1108	9.1978	2.2585	10.0222
BL-41	CTRP2	5.1946	6.5074	4.434	2.2899
OCI-Ly10	CTRP2; CTRP1	5.2042	12.6652	1.3761	14.9291
MOLP-2	CTRP2	5.2147	10.3117	2.5512	10.1333
MHH-CALL-3	CTRP2	5.3311	12.7554	1.4251	14.4267
P31/FUJ	GDSC1	5.4675	6.7777	3.5618	0.6105
Karpas-620	CTRP2	5.4873	6.8308	4.4879	1.6096
KM-H2	GDSC1	5.5102	14.9114	-0.2539	22.9615
KY821	GDSC1	5.5127	9.4317	2.4177	7.8394
KMM-1	CTRP2	5.5357	13.234	1.3515	14.3218
Karpas-620	CTRP2	5.6205	7.1102	4.4431	1.6079
KMM-1	CTRP2	5.7567	9.3476	3.4537	5.4298
SCC-3	GDSC1	5.8062	7.0933	3.5807	0.328
ME1	GDSC1	5.8624	16.7999	-0.9219	24.5345
MOLP-2	CTRP2	6.1496	9.0617	3.8653	3.1849
THP-1	GDSC1	6.2089	13.0965	1.1349	14.2567
OPM-2	GDSC1	6.2725	16.5573	-0.5002	21.8801
Loucy	GDSC1	6.4273	20.5871	-2.3678	27.5142
HDLM-2	GDSC1	6.5543	21.7399	-2.8416	28.4061
OCI-AML-5	CTRP2	6.5845	18.3679	-0.3814	18.4057
NOMO-1	GDSC1	6.8916	20.43	-1.9475	25.2743
ARH-77	GDSC1	6.9317	16.3654	0.0571	17.8958

Cancer Drug Sensitivity Data Curated from 59 Cell Line(s) in Oesophagus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
TE15	CTRP2	2.7985	10.2494	0.3953	23.8396
TE8	CTRP2	4.8132	15.2027	-0.2287	21.2609
TE8	CTRP2	5.3982	7.092	4.2984	2.5154
KYSE-270	GDSC1	-2.405	0.5816	-2.4292	75.6353
TE-15	GDSC1	-1.4165	3.8227	-1.8637	61.944
T.T	GDSC1	-1.1207	5.0701	-1.9133	58.483
TE-10	GDSC1	-0.783	4.7181	-1.4322	56.4633
TE-8	GDSC1	-0.4133	5.6768	-1.3596	53.1883
KYSE-510	GDSC1	-0.0971	2.7718	-0.2057	51.1055
KYSE-140	GDSC1	-0.0809	5.2488	-0.8478	50.685
KYSE-450	GDSC1	0.006	9.6325	-2.5783	49.9679
KYSE-70	GDSC1	0.2995	5.4289	-0.5023	47.4012
TE-1	GDSC1	0.5188	6.1732	-0.5537	45.7862
COLO 680N	GDSC1	0.6423	6.2625	-0.4591	44.7664
KYSE-410	GDSC1	0.7013	8.5881	-1.4041	45.5755
TE-11	GDSC1	0.7571	5.0497	0.1274	42.7367
KYSE-150	GDSC1	1.35	5.5405	0.5787	37.0293
OE21	GDSC1	1.3692	7.7357	-0.3447	39.8841
KYSE-180	GDSC1	1.7252	5.7801	0.8775	33.3225
TE-5	CTRP2	2.1058	6.6246	1.3007	22.4815
OE21	CTRP2	2.1486	7.4796	0.9987	23.4629
OE19	GDSC1	2.5444	8.1744	0.6031	30.1752
TE-6	GDSC1	2.5783	10.1662	-0.3355	33.7257
KYSE-70	CTRP2	2.5996	8.2363	1.1331	23.221
TE-5	GDSC1	2.6575	17.681	-3.9892	40.6593
TE-9	GDSC1	3.057	11.3505	-0.4879	32.1994
TE-6	CTRP2	3.1106	7.4222	2.0163	17.0134
OE33	GDSC1	3.3969	12.6711	-0.8478	32.0404
KYSE-140	CTRP2; CTRP1	3.4947	10.0307	1.1736	19.392
KYSE-520	GDSC1	3.7301	5.0142	3.2535	6.9432
KYSE-140	CTRP2; CTRP1	4.0202	6.2504	3.4704	8.9877
KYSE-410	CTRP2; CTRP1	4.083	6.9348	3.2209	9.832
KYSE-450	CTRP1	4.1167	5.1296	4.0105	14.2608
TE-14	CTRP2	4.4887	5.844	4.1219	5.1029
TE-4	CTRP2	4.5515	8.1627	3.0576	9.3525
KYSE-150	CTRP2	4.6319	5.3103	4.5015	3.2282
TE-1	CTRP2	4.6522	12.4515	1.0092	18.4589
EC-GI-10	CTRP2	4.6575	9.6854	2.3941	11.8847
KYSE-180	CTRP2	4.7545	11.6837	1.4801	15.3546
KYSE-70	CTRP2	4.7625	7.1281	3.7592	5.9721
TE-6	CTRP2	4.8805	7.0957	3.8791	5.2238
TE-11	CTRP2	4.8812	8.6571	3.1004	8.4899
TE-9	CTRP2	4.94	12.1268	1.4158	15.2273
TE-10	CTRP2	5.0175	7.1173	3.9854	4.5033
TE-4	CTRP2	5.0914	6.486	4.3623	2.7775
COLO 680N	CTRP2	5.0994	7.2522	3.986	4.3437
TE-10	CTRP2	5.2332	13.3587	1.0435	16.0552
TE-9	CTRP2	5.2732	6.4327	4.5305	1.7566
TE-1	CTRP2	5.3665	7.8156	3.9172	4.1517
KYSE-410	CTRP2; CTRP1	5.3941	7.8673	3.9233	4.1601
KYSE-180	CTRP2	5.407	6.7902	4.4521	1.8707
EC-GI-10	GDSC1	6.3713	8.1861	3.4044	0.5688
COLO 680N	CTRP2	6.7356	8.2301	4.5452	0.3622
KYSE-510	CTRP2	6.7591	13.3687	2.2102	8.9056
KYSE-450	CTRP2; CTRP1	7.3893	14.3224	2.1958	8.1165
OE33	CTRP2	7.533	17.4106	0.7925	12.9981
OE19	CTRP2	7.6104	13.6001	2.6691	5.9535
KYSE-520	CTRP2	8.9169	18.2087	1.3417	9.162
KYSE-30	CTRP2	12.4178	31.1437	-2.491	15.9835

Cancer Drug Sensitivity Data Curated from 88 Cell Line(s) in Pancreas Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
N2a-PK1	CTRP2	7.8483	15.1374	2.0996	7.7941
HPAC	GDSC1	-3.243	12.185	-7.0221	61.0631
MIA PaCa-2	GDSC1	-1.8292	4.7476	-2.5804	63.0789
KP-2	GDSC1	-1.2561	2.2198	-1.3662	63.1875
PSN1	GDSC1	-0.9514	2.2004	-1.0395	60.4293
KP-1N	GDSC1	0.5116	5.2983	-0.2266	45.3743
SUIT-2	GDSC1	0.5215	6.0655	-0.508	45.7067
HuP-T4	GDSC1	1.1613	6.5363	-0.0289	40.3191
BxPC-3	GDSC1	1.1874	7.4827	-0.4149	41.1286
Panc 10.05	GDSC1	1.3739	5.4477	0.6406	36.6162
MZ-PC-1	GDSC1	1.4295	4.5706	1.0204	34.4742
CFPAC-1	GDSC1	1.8091	9.0423	-0.5185	37.949
Panc 03.27	GDSC1	1.9368	11.6877	-1.6745	39.9039
BxPC-3	CTRP2	1.9729	10.7077	-0.6278	29.2353
PaTu 8988t	GDSC1	2.2986	3.8971	2.1702	22.104
SW1990	GDSC1	2.8296	7.0567	1.4128	24.3988
HPAF-II	GDSC1	2.851	13.3533	-1.6656	36.2446
Capan-2	CTRP1	2.9004	5.9698	2.4041	34.0774
Capan-2	GDSC1	3.1992	8.6626	0.9718	25.2776
Hs 766T	GDSC1	3.385	7.7827	1.5745	20.8617
KP-4	GDSC1	3.4228	8.5512	1.2271	22.8645
PL4	GDSC1	3.5115	12.0324	-0.4302	30.2223
Panc 02.03	GDSC1	3.5657	5.3229	2.9491	10.0068
HuP-T3	GDSC1	3.7298	14.2927	-1.3732	32.3938
YAPC	GDSC1	3.8141	4.5711	3.5479	4.3015
KP-3	GDSC1	3.8667	13.7293	-0.9761	30.7618
Capan-1	GDSC1	3.9083	7.3861	2.2299	14.1622
PaTu 8902	CTRP2; CTRP1	3.9605	5.2443	3.8049	8.4234
Panc 03.27	CTRP1	4.0034	5.8795	3.6122	18.1771
Panc 04.03	GDSC1	4.0134	22.6157	-5.2967	38.5664
PSN1	CTRP2	4.2219	7.7713	2.9468	10.5427
PK-59	CTRP2	4.2357	10.857	1.4394	17.7209
SUIT-2	CTRP2; CTRP1	4.2397	6.1344	3.7456	7.3288
HPAC	CTRP2; CTRP1	4.2575	5.2865	4.113	6.269
HuP-T4	CTRP2; CTRP1	4.2583	13.8696	-0.0302	23.1224
Panc 10.05	CTRP2; CTRP1	4.2844	11.5081	1.1681	17.6109
QGP-1	CTRP2; CTRP1	4.2913	5.4893	4.0742	5.9028
Panc 10.05	CTRP1	4.4298	8.8182	2.6322	23.4703
QGP-1	CTRP2; CTRP1	4.5014	11.07	1.577	15.5765
KP-3	CTRP2; CTRP1	4.5199	16.3882	-1.061	24.3776
Panc 08.13	CTRP2	4.5624	7.1659	3.5594	7.2392
Capan-2	CTRP2; CTRP1	4.5707	7.2	3.5585	7.3098
PaTu 8902	CTRP2; CTRP1	4.5781	5.8257	4.2264	4.5487
HuP-T3	CTRP2	4.6929	7.642	3.4421	7.4453
PaTu 8988s	CTRP2	4.7052	6.6183	3.9596	5.2598
HuP-T4	CTRP2; CTRP1	4.739	6.6289	3.9936	5.1312
AsPC-1	CTRP2	4.7985	7.5576	3.5774	6.6577
MIA PaCa-2	CTRP2	4.7989	11.2929	1.7133	14.35
L3.3	CTRP2	4.8145	7.2692	3.735	6.3898
SW1990	CTRP2	4.8195	7.3078	3.7202	6.0158
HPAC	CTRP2; CTRP1	4.8343	5.7322	4.5207	2.7338
Panc 04.03	CTRP2	4.8638	8.2883	3.2696	7.8152
SNU-410	CTRP2	4.8745	8.3195	3.2632	7.8204
AsPC-1	GDSC1	4.8813	9.5513	1.9202	13.0701
Capan-1	CTRP2	4.9361	8.5278	3.2117	7.914
TCC-Pan2	CTRP2	4.9394	9.4634	2.7468	10.5489
SU.86.86	GDSC1	4.9781	23.8549	-5.1246	36.1362
Panc 03.27	CTRP2; CTRP1	4.9886	6.7773	4.1404	3.9945
PaTu 8988t	CTRP2	4.9902	5.619	4.7108	1.5105
KP-4	CTRP2	5.0095	13.3413	0.8668	17.1451
SU.86.86	CTRP2	5.0225	6.4981	4.2992	3.1749
YAPC	CTRP2	5.0615	5.81	4.6758	1.5168
BxPC-3	CTRP2	5.074	8.2111	3.4856	6.4949
PK-59	CTRP2	5.0784	7.7041	3.7428	5.406
SNU-213	CTRP2	5.0842	6.4272	4.3859	2.692
KP-3	CTRP2; CTRP1	5.1132	8.6885	3.2892	7.3264
Panc 08.13	GDSC1	5.1558	10.1261	1.8386	12.799
CFPAC-1	CTRP2; CTRP1	5.2247	6.625	4.4093	2.4242
KP-4	CTRP2	5.2595	6.8592	4.3094	2.6982
Panc 02.03	CTRP2	5.3006	8.1277	3.7107	5.1304
SNU-410	CTRP2	5.3487	15.8728	-0.1184	24.8772
TCC-Pan2	CTRP2	5.398	6.9657	4.3601	2.2616
CFPAC-1	CTRP2; CTRP1	5.4021	9.307	3.2136	7.1096
PaTu 8902	GDSC1	5.4367	13.5114	0.3821	20.3389
SU.86.86	CTRP2	5.5582	7.0227	4.4437	1.6882
Panc 05.04	CTRP2	5.5583	7.458	4.2344	2.5314
HPAF-II	CTRP2	5.576	7.9548	4.0049	3.4439
YAPC	CTRP2	5.9394	14.0643	1.2568	14.8291
DAN-G	GDSC1	5.9668	11.5126	1.7293	11.3103
L3.3	CTRP2	6.0189	8.6706	3.965	2.965
SNU-213	CTRP2	6.2732	7.6104	4.5834	0.5054
SUIT-2	CTRP2; CTRP1	6.3543	14.5968	1.3218	13.0456
DAN-G	CTRP2	6.8915	18.4059	-0.1664	17.2139
HPAF-II	CTRP2	7.39	15.947	1.4026	11.0304
PK-45H	CTRP2	8.0679	9.6449	4.5416	0.0703
Hs 766T	CTRP2	8.1141	19.8179	0.0332	14.6538
Panc 05.04	CTRP2	8.227	21.9556	-0.9279	18.2263
KP-2	CTRP2	9.0411	20.1667	0.4985	11.8496

Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Aero Dig Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KYSE-50	GDSC1	0.5595	4.4274	0.1204	44.3296
HCE-4	GDSC1	1.1334	8.4163	-0.8918	42.4098
TE-12	GDSC1	1.6122	6.646	0.3894	36.1271
KYSE-220	GDSC1	2.4716	6.4229	1.3605	26.4987

Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Ascites Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
COLO 684	GDSC1	1.0321	12.665	-3.0003	45.3587
COLO 684	CTRP2	3.3824	9.9042	1.1208	19.7887

Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Autonomic Ganglia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MHH-NB-11	CTRP2	-2.8223	4.5566	-3.4126	51.9427
SK-N-SH	GDSC1	-2.3558	4.0449	-2.9486	66.9458
SJNB-7	GDSC1	-1.215	0.8151	-1.2215	64.6751
CHP-212	GDSC1	0.2519	3.5326	0.0271	47.2574
SK-N-SH	CTRP2	0.7796	7.2771	-0.3654	32.08
NB(TU)1	GDSC1	0.909	8.5905	-1.1963	44.1512
Kelly	CTRP2	0.9701	7.0887	-0.0894	30.6447
MHH-NB-11	GDSC1	1.2813	10.0046	-1.4872	42.6018
SK-N-DZ	GDSC1	1.4754	44.1714	-18.2265	48.1094
SJNB-10	GDSC1	1.6233	7.1535	0.1749	36.8453
SJNB-13	GDSC1	1.6517	7.3687	0.1063	36.9166
SK-N-MC-IXC	GDSC1	1.6893	4.2285	1.4124	30.6132
SK-N-DZ	CTRP2	1.8504	6.3362	1.1367	23.8213
CHP-212	CTRP2	2.0719	6.3844	1.3564	22.3744
NH-12	GDSC1	2.1006	5.0065	1.586	27.1063
SK-N-AS	CTRP2	2.42	8.0557	1.0306	22.5952
KP-N-YS	GDSC1	2.9817	8.6472	0.7814	27.2486
SJNB-12	GDSC1	2.991	7.2635	1.4664	23.3045
SiMa	GDSC1	3.2426	5.2738	2.6583	13.6821
TGW	GDSC1	3.253	4.1496	3.1395	10.0962
SiMa	CTRP2	3.3379	6.7179	2.5587	14.2877
IMR-5	GDSC1	3.3947	8.0581	1.4468	21.6391
SK-N-AS	GDSC1	3.4523	3.9061	3.4251	7.022
SJNB-14	GDSC1	3.6761	14.0441	-1.2944	32.3583
LA-N-6	GDSC1	3.7214	5.619	2.9481	9.3621
NH-6	CTRP2	3.8137	10.2382	1.362	17.8558
SK-N-BE(2)	CTRP2	3.9262	11.2905	0.9467	19.1601
GOTO	GDSC1	3.9551	9.4639	1.2306	20.719
Kelly	GDSC1	3.9744	9.6369	1.1602	21.0624
NB69	GDSC1	3.978	6.0001	2.9815	8.1102
CHP-126	CTRP2	4.2444	12.3729	0.6938	25.0567
Kelly	CTRP2	4.2939	5.7242	3.9753	6.1895
CHP-126	GDSC1	4.3415	9.4469	1.5557	17.2853
KP-N-SI9s	CTRP2	4.3677	7.2936	3.3158	8.6867
GI-ME-N	GDSC1	4.6748	7.3209	2.8628	6.7889
NB1	CTRP2	4.8366	5.4352	4.6571	2.0793
SK-N-FI	CTRP2	5.0212	19.5012	-2.2033	26.2099
CHP-126	CTRP2	5.1067	7.446	3.8951	4.7118
SK-N-BE(2)-M17	GDSC1	5.2891	11.4734	1.2756	15.9705
SK-N-FI	GDSC1	5.4575	7.7537	3.1535	2.8914
SJNB-6	GDSC1	5.493	17.7619	-1.6798	27.9607
KP-N-YN	GDSC1	5.621	9.5337	2.4392	7.428
KP-N-SI9s	CTRP2	5.6916	16.5843	-0.1954	19.4326
SJNB-5	GDSC1	6.0786	11.7005	1.7137	11.1298
NB1	CTRP2	6.5592	14.4886	1.5176	11.8991
KP-N-YN	CTRP2	7.0701	8.9481	4.4129	0.5088
NB1	GDSC1	8.174	25.516	-3.509	26.5868

Cancer Drug Sensitivity Data Curated from 14 Cell Line(s) in Biliary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HuCC-T1	GDSC1	1.8547	9.8833	-0.8769	38.6257
SNU-1079	CTRP2	3.007	10.5988	0.4286	23.1961
HuH-28	CTRP2	4.0254	7.7383	2.7763	11.6989
SNU-478	CTRP2	4.2012	9.9344	1.8655	15.0078
HuH-28	CTRP2	4.5256	6.9673	3.6225	7.0594
SNU-869	CTRP2	4.6038	6.5762	3.8862	5.791
SNU-478	CTRP2	4.9197	7.7265	3.5981	6.3244
SNU-1196	CTRP2	5.2263	7.8655	3.7824	4.9636
HuCC-T1	CTRP2	5.2417	7.3376	4.0578	3.7816
SNU-308	CTRP2	5.2524	7.6925	3.8895	4.4677
HuCC-T1	CTRP2	5.3185	10.322	2.6304	9.6117
SNU-308	CTRP2	5.4233	9.8979	2.9257	8.1937
SNU-245	CTRP2	5.5702	8.6686	3.6497	4.9224
SNU-1196	CTRP2	7.0022	15.3162	1.4346	11.5032

Cancer Drug Sensitivity Data Curated from 140 Cell Line(s) in Breast Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MCF-7	GDSC1	-2.4389	2.1996	-2.63	71.4092
HCC2157	GDSC1	-1.7193	10.4814	-4.7114	57.3708
CAL-148	CTRP2	-1.7125	7.7512	-3.2125	46.5051
EFM-192A	GDSC1	-1.2865	5.6954	-2.3074	58.8841
DU4475	CTRP2	-1.247	7.0235	-2.4483	43.875
JIMT-1	GDSC1	-1.117	8.2441	-3.1241	56.0838
OCUB-M	GDSC1	-1.0624	4.4925	-1.6667	58.6792
CAL-148	GDSC1	-0.3899	23.9841	-9.8508	50.8692
MRK-nu-1	GDSC1	-0.2345	27.725	-11.553	50.4569
HCC2218	CTRP2	-0.0975	5.6232	-0.7352	36.1225
HCC70	GDSC1	0.0462	8.6996	-2.1191	49.7298
CAL-85-1	GDSC1	0.0646	6.4161	-1.1317	49.5163
AU565	GDSC1	0.2442	8.6101	-1.8774	48.5296
EFM-19	GDSC1	0.378	6.7997	-0.9573	47.1941
HCC202	GDSC1	0.4216	15.1865	-4.7976	48.4767
DU4475	GDSC1	0.5373	9.7729	-2.1105	47.0286
CAL-51	GDSC1	0.7841	9.2826	-1.6387	45.3524
MDA-MB-330	GDSC1	0.8639	5.9074	-0.0822	42.4641
MDA-MB-361	GDSC1	0.8774	5.2292	0.1922	41.6591
HCC1569	GDSC1	1.2526	5.5683	0.4643	38.1229
ZR-75-30	GDSC1	1.3542	5.2611	0.6914	36.5305
HCC1419	GDSC1	2.2669	6.4428	1.1461	28.8242
HCC1937	GDSC1	2.3532	3.4073	2.3232	20.7752
MDA-MB-231	GDSC1	2.4582	3.9877	2.3207	20.1735
MDA-MB-436	GDSC1	2.5279	10.0676	-0.3337	33.9457
AU565	CTRP2	2.5681	11.3534	-0.3536	26.8351
HCC38	GDSC1	2.6058	6.5241	1.447	25.2838
BT-549	GDSC1	2.6346	5.6647	1.8683	22.3744
HCC1187	GDSC1	2.7354	11.6375	-0.9179	34.826
SK-BR-3	CTRP2	2.8288	11.8559	-0.3471	26.1459
HCC1954	GDSC1	2.9323	7.6752	1.2112	25.1268
CAL-120	GDSC1	2.942	10.7191	-0.2775	31.9492
HCC1395	GDSC1	2.9748	7.0957	1.5324	22.9606
HCC1500	GDSC1	3.1837	9.849	0.3702	28.3323
Hs 578T	GDSC1	3.266	5.4466	2.6009	14.0072
HCC1806	GDSC1	3.355	9.3405	0.7749	25.6571
MDA-MB-157	GDSC1	3.3572	11.8679	-0.4816	30.9918
MDA-MB-415	GDSC1	3.3592	13.6287	-1.3582	33.6415
T-47D	GDSC1	3.3925	20.2601	-4.6416	39.3568
COLO 824	GDSC1	3.3975	10.9755	-0.0018	29.0394
HCC2218	GDSC1	3.547	12.8816	-0.8237	31.413
UACC-893	GDSC1	3.5547	18.3052	-3.527	37.4094
HCC1569	CTRP2	3.6347	7.7749	2.3798	14.2461
MFM-223	GDSC1	3.6424	4.1939	3.5438	5.1462
MDA-MB-468	GDSC1	3.688	14.9118	-1.718	33.4366
MDA-MB-453	CTRP2	3.7139	11.0422	0.8754	19.9082
HDQ-P1	GDSC1	3.8976	10.2393	0.7946	23.3872
CAL-85-1	CTRP2	3.9049	9.7289	1.6958	16.3469
CAMA-1	GDSC1	3.9435	5.8944	3.0053	8.0499
HCC1428	CTRP2	3.9496	10.2798	1.4664	17.1425
ZR-75-1	CTRP2	3.9838	11.5514	0.8697	20.549
Evsa-T	GDSC1	4.053	12.5441	-0.2279	27.4868
MDA-MB-175-VII	GDSC1	4.077	5.7159	3.2054	5.9935
MCF-7	CTRP2; CTRP1	4.1995	13.9035	-0.0985	22.2077
MCF-7	CTRP2; CTRP1	4.2037	8.1408	2.7579	11.4442
HCC1500	CTRP2	4.2715	14.3335	-0.259	22.4977
T-47D	CTRP2	4.3244	7.1098	3.3639	8.5884
Hs 578Bst	CTRP2	4.3755	13.7208	0.1369	21
BT-20	GDSC1	4.4904	22.08	-4.6346	36.5906
HCC1599	GDSC1	4.5195	15.7108	-1.4283	30.012
CAL-148	CTRP2	4.5746	8.3553	2.9828	9.6146
EFM-192A	CTRP2	4.5779	12.1999	1.0709	17.2782
MDA-MB-453	GDSC1	4.6922	8.7359	2.1812	11.8206
BT-474	CTRP2	4.7325	7.891	3.3535	7.7327
HCC1395	CTRP2	4.8283	8.3386	3.2139	8.1205
HCC1419	CTRP2	4.8946	10.1666	2.3574	11.554
ZR-75-30	CTRP2	4.9531	8.2038	3.3879	7.1405
HCC1143	CTRP2	4.979	13.1626	0.9306	18.0398
HCC1569	CTRP2	5.0018	7.035	4.0134	4.4167
MDA-MB-231	CTRP2	5.0662	9.7845	2.6925	9.8309
MDA-MB-415	CTRP2	5.0775	12.2541	1.4671	14.7564
JIMT-1	CTRP2	5.0846	7.689	3.7555	5.3406
CAMA-1	CTRP2	5.1214	8.2823	3.4891	6.39
HMC-1-8	CTRP2	5.1357	7.4529	3.9154	4.5725
HCC1806	CTRP2	5.1497	7.5879	3.8593	4.782
ZR-75-1	CTRP2	5.1959	6.9315	4.2239	3.1673
HCC1954	CTRP2	5.197	7.2654	4.0584	3.8593
HCC1143	CTRP2	5.222	7.1876	4.117	3.5687
CAL-51	CTRP2	5.3417	7.8471	3.8824	4.3395
UACC-812	GDSC1	5.5504	8.2248	2.997	3.7473
HCC1806	CTRP2	5.5699	7.1648	4.3837	1.9116
JIMT-1	CTRP2	5.6087	7.003	4.4859	1.4556
BT-483	GDSC1	5.6635	7.6851	3.2898	1.746
HCC1937	CTRP2	5.7053	11.6408	2.2795	10.353
CAL-51	CTRP2	5.7611	15.4279	0.4372	17.2161
MDA-MB-231	CTRP2	5.7794	7.9602	4.1442	2.5784
BT-474	GDSC1	5.7855	13.949	0.4237	19.1392
HCC1395	CTRP2	5.7979	16.025	0.1687	18.0541
BT-549	CTRP2	5.8567	11.1234	2.6524	8.5698
Hs 578T	CTRP2	5.8773	10.8864	2.7852	7.9902
CAMA-1	CTRP2	5.8814	8.1374	4.1274	2.5065
UACC-812	CTRP2	5.9278	32.0802	-7.7445	33.5562
HCC1937	CTRP2	5.9974	8.7844	3.8966	3.2657
CAL-120	CTRP2	6.0449	8.5247	4.0507	2.5944
KPL-1	CTRP2	6.1641	6.9454	4.7904	0.0995
HCC1954	CTRP2	6.4042	20.6653	-1.6638	22.34
MDA-MB-361	CTRP2	6.4131	19.3751	-1.0147	20.5726
KPL-1	CTRP2	6.4793	7.3362	4.7692	0.0648
HCC38	CTRP2	6.505	11.7336	2.825	6.843
CAL-120	CTRP2	6.5348	7.7381	4.647	0.2325
MDA-MB-468	CTRP2	7.0054	15.8627	1.1697	12.4739
HCC202	CTRP2	7.0273	11.5069	3.2782	4.3525
BT-20	CTRP2	7.1829	16.4908	0.9908	12.8399
HMC-1-8	CTRP2	7.2816	16.7773	0.9218	12.9312
HDQ-P1	CTRP2	7.3867	9.4276	4.364	0.4782
HCC1428	GDSC1	7.4677	27.463	-4.9818	30.8251
HDQ-P1	CTRP2	8.5459	23.8374	-1.6179	18.791
BT 239	CTRP2	0.4529	6.9843	-0.6037	33.8335
BT 416	CTRP2	0.5284	6.1961	-0.2406	32.5464
BT 286	CTRP2	0.9685	9.938	-1.2853	33.8792
BT 231	CTRP2	1.2437	8.3937	-0.3302	30.5105
BT 330	CTRP2	1.2826	14.2304	-2.9656	36.2824
BT 271	CTRP2	1.3424	17.3258	-4.4007	38.1861
BT 428	CTRP2	2.2033	10.4423	-0.2768	27.5762
BT 131	CTRP2	2.2707	9.6344	0.1655	26.003
BT 422	CTRP2	2.4882	15.8257	-2.601	32.5463
BT 245	CTRP2	2.5449	14.4837	-1.8917	30.9164
BT 145	CTRP2	2.8189	7.9461	1.4857	19.8285
BT147	CTRP2	2.8425	9.3357	0.8699	22.0607
BT 248	CTRP2	3.2913	6.6354	2.5457	14.4626
BT 498	CTRP2	3.3617	9.6285	1.2338	19.414
BT 112	CTRP2	3.5532	11.5273	0.4894	21.657
BT 228	CTRP2	3.5737	8.0315	2.1994	15.1198
BT 320	CTRP2	3.5739	8.0279	2.2013	15.1118
BT 482	CTRP2	3.6042	16.5401	-1.9438	28.5473
BT 172	CTRP2	3.6224	14.7798	-1.0538	26.2641
BT 139	CTRP2	4.1967	6.9164	3.3336	9.0139
BT 216	CTRP2	4.7732	17.2926	-1.3071	24.4712
BT 340	CTRP2	4.8001	18.884	-2.08	26.3552
BT 159	CTRP2	4.8668	10.936	1.9493	13.2712
BT 440	CTRP2	5.1078	13.9685	0.635	17.7801
BT164	CTRP2	5.1207	12.1098	1.5751	14.2523
BT 444	CTRP2	5.1452	17.3978	-1.0485	23.023
BT 232	CTRP2	5.1957	15.8162	-0.2159	20.4517
BT 504	CTRP2	5.3607	22.4463	-3.3944	28.1087
BT 359	CTRP2	5.7154	18.7138	-1.2395	22.4579
BT 224	CTRP2	6.7579	11.2749	3.2152	4.938
BT 328	CTRP2	7.0358	18.5905	-0.1492	16.9199
BT 179	CTRP2	7.0965	15.0167	1.6477	10.5596
BT 333	CTRP2	7.2569	20.8143	-1.0812	19.3331

Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Tongue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
YD-38	CTRP2	4.8187	13.4061	0.674	18.2249
YD-38	CTRP2	5.4302	6.4478	4.6323	1.1136

Cancer Drug Sensitivity Data Curated from 118 Cell Line(s) in Central Nervous System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Daoy	GDSC1	-4.5717	2.4875	-4.9892	78.2719
D-566MG	GDSC1	-2.6029	21.7115	-10.8198	55.7913
NMC-G1	GDSC1	-1.5145	4.3516	-2.1177	61.824
YKG-1	GDSC1	-0.8667	4.9694	-1.6044	56.8643
KS-1 [Human Krukenberg tumour]	GDSC1	-0.8138	7.4935	-2.4948	54.9153
SW1783	GDSC1	-0.163	8.0406	-2.0459	50.9979
SF295	GDSC1	-0.0245	6.9879	-1.4575	50.1704
ONS-76	GDSC1	0.4844	7.0358	-0.9451	46.4602
H4	GDSC1	0.9037	7.2217	-0.5904	43.2403
Hs 683	GDSC1	0.9069	6.7779	-0.3961	42.8508
GB-1	GDSC1	1.0468	12.0867	-2.7076	45.0653
8-MG-BA	GDSC1	1.1615	3.6055	1.0004	36.3907
Onda 11	GDSC1	1.2584	5.7345	0.4045	38.3041
MOG-G-CCM	GDSC1	1.4014	5.6458	0.5914	36.6414
D-542MG	GDSC1	1.4439	7.3844	-0.1105	38.8085
D283 Med	CTRP2	1.4477	5.7182	0.9165	25.8154
SF126	GDSC1	1.5936	10.0301	-1.1974	40.5747
A-172	GDSC1	1.5983	4.0769	1.3576	31.5074
GI-1	GDSC1	1.9447	5.4496	1.2442	30.072
KNS-81-FD	GDSC1	1.956	8.926	-0.3211	36.6393
KNS-42	GDSC1	2.2362	11.214	-1.165	37.5615
SK-MG-1	GDSC1	2.2531	7.3862	0.6968	31.2114
DBTRG-05MG	GDSC1	2.2707	9.9901	-0.5352	35.7523
MOG-G-UVW	GDSC1	2.5011	4.6012	2.1681	20.9848
U-251MG	GDSC1	2.5903	6.7363	1.3325	26.062
SF268	GDSC1	2.6539	8.0352	0.7743	28.8158
Becker	GDSC1	2.682	7.2841	1.1622	26.6045
U-118MG	GDSC1	2.7771	8.0733	0.872	27.7286
GaMG	GDSC1	2.8713	9.5676	0.2274	30.309
LN-18	GDSC1	2.9345	5.4135	2.2853	17.922
SNB-75	GDSC1	2.9438	11.0904	-0.4597	32.5684
SW1088	GDSC1	3.0228	5.6265	2.2768	17.5603
Onda 10	GDSC1	3.0746	3.9762	2.9965	12.0787
YH-13	GDSC1	3.1671	4.4935	2.921	12.1053
LNZTA3WT4	GDSC1	3.1749	5.1661	2.6398	14.1405
D283 Med	GDSC1	3.2524	4.6703	2.9379	11.5478
T98G	GDSC1	3.3724	7.1794	1.8611	18.983
ONS-76	CTRP2	3.4505	9.1173	1.5641	17.9325
D-423MG	GDSC1	3.5202	8.6038	1.287	22.1002
42-MG-BA	GDSC1	3.536	4.9349	3.106	8.9326
SNU-466	CTRP2	3.5391	11.2163	0.6289	21.2023
D-392MG	GDSC1	3.6794	6.8199	2.3147	14.4176
CAS-1	GDSC1	3.732	10.8525	0.348	26.2223
SF539	GDSC1	3.7468	5.8071	2.8777	9.8098
Hs 683	CTRP2	3.875	13.2816	-0.0852	24.1527
SF539	CTRP2	3.8991	5.8237	3.5204	9.0268
M059K	CTRP2	4.0077	6.422	3.3751	9.3131
LN-229	GDSC1	4.149	9.0226	1.6118	17.6077
SF268	CTRP2	4.1906	8.9876	2.3227	13.18
LN-405	GDSC1	4.2471	12.0592	0.1744	25.1206
U-118MG	CTRP2	4.2719	10.4704	1.6635	15.6557
42-MG-BA	CTRP2	4.3372	8.4921	2.7008	11.3002
SNU-466	CTRP2	4.4025	5.0296	4.3479	4.467
AM-38	GDSC1	4.4563	12.2557	0.2459	24.0765
KNS-60	CTRP2	4.4728	12.2231	0.9683	17.8806
PFSK-1	GDSC1	4.5298	9.1338	1.8601	14.6095
LN-18	CTRP2	4.5597	5.159	4.4802	3.5132
SW1088	CTRP2	4.6282	13.4041	0.5129	20.3519
LN-18	CTRP2	4.6655	5.149	4.5983	2.765
GMS-10	CTRP2	4.6856	5.3496	4.5417	2.926
KNS-60	CTRP2	4.6875	5.8764	2.665	0.198
SNB-75	CTRP2	4.7389	6.7865	3.9072	5.4042
D-502MG	GDSC1	4.7686	8.0247	2.5867	8.6023
GaMG	CTRP2; CTRP1	4.7866	7.6713	3.5194	7.0096
KINGS-1	GDSC1	4.8359	15.0527	-0.8461	27.1985
SF295	CTRP2; CTRP1	4.8531	6.9158	3.9538	5.0532
GOS-3	CTRP2	4.875	13.4823	0.6835	18.0759
LN-229	CTRP2; CTRP1	4.8756	7.527	3.669	6.1999
GB-1	CTRP2	4.9392	6.9223	4.0164	4.5284
ONS-76	CTRP2	4.9394	9.1914	2.8828	9.2851
YKG-1	CTRP2	4.9427	11.6167	1.6731	14.2193
Daoy	CTRP2	4.9455	12.7638	1.1019	16.4073
YH-13	CTRP2	5.0088	8.3986	3.3375	7.2429
U-87MG ATCC	GDSC1	5.0228	7.154	3.1719	3.6228
SW1088	CTRP2	5.2139	6.7612	4.3228	2.7211
SNU-738	CTRP2	5.248	6.3364	4.5592	1.6787
8-MG-BA	CTRP2	5.2743	10.3482	2.5816	9.896
CAS-1	CTRP2	5.3234	21.7548	-3.0795	27.5481
SNU-489	CTRP2	5.3337	9.0695	3.2676	6.927
KALS-1	CTRP2	5.3395	10.1342	2.741	9.1142
M059J	GDSC1	5.352	12.0499	1.0386	17.1589
SF126	CTRP2	5.3976	7.7217	3.9875	3.8057
KALS-1	GDSC1	5.4851	12.5157	0.9075	17.4973
Daoy	CTRP2	5.5427	9.6396	3.1477	7.0578
D-263MG	GDSC1	5.5822	10.0535	2.1685	9.3904
CAS-1	CTRP2	5.6153	7.1715	4.4107	1.7423
NMC-G1	CTRP2	5.7317	9.4773	3.3714	5.8104
SNU-489	CTRP2	5.7462	7.7474	4.2235	2.3078
SNU-1105	CTRP2	5.786	8.0876	4.0876	2.7954
U-87MG ATCC	CTRP2	5.8197	7.832	4.2316	2.1777
DK-MG	GDSC1	5.8632	7.493	3.4564	0.723
KALS-1	CTRP2	5.8907	8.7137	3.8581	3.5701
KNS-81	CTRP2	5.9129	9.5157	3.4848	5.0566
GaMG	CTRP2; CTRP1	5.9197	12.8449	1.858	12.5182
SNU-626	CTRP2	6.0021	7.6105	4.4442	1.1665
KNS-42	CTRP2	6.1389	10.8859	2.978	6.7791
SNU-201	CTRP2	6.1988	7.759	4.4856	0.8498
SNU-1105	CTRP2	6.2032	13.4704	1.7539	11.5841
NMC-G1	CTRP2	6.2066	8.3936	4.2106	1.7962
SF295	CTRP2; CTRP1	6.3047	13.8518	1.6526	11.8748
SF126	CTRP2	6.3714	10.2489	3.4477	4.5398
SNU-626	CTRP2	6.3718	14.2537	1.4937	12.3003
SNU-201	CTRP2	6.4258	13.7487	1.783	11.1007
DBTRG-05MG	CTRP2	6.4677	8.4687	4.3224	1.154
SW1783	CTRP2	6.4835	10.0297	3.6247	3.6939
T98G	CTRP2	6.5078	10.1409	3.5881	3.8055
GB-1	CTRP2	6.5507	14.5472	1.4825	12.046
KNS-81	CTRP2	6.5516	7.7305	4.6566	0.2092
CCF-STTG1	CTRP2	6.5906	11.2311	3.1254	5.5192
U-87MG ATCC	CTRP2	6.746	12.3176	2.7096	6.9517
A-172	CTRP2	7.1528	11.8544	3.195	4.5174
LN-229	CTRP2; CTRP1	7.5296	18.7482	0.1482	15.2311
Becker	CTRP2	7.6608	18.3431	0.4293	14.0427
DBTRG-05MG	CTRP2	8.2672	16.6321	1.6659	8.8422
DK-MG	CTRP2	9.6279	23.0462	-0.4828	14.1209
TM-31	CTRP2	10.3357	22.5338	0.2177	11.118
U-251MG	CTRP2	10.4727	24.5644	-0.6473	13.522
KG-1-C	CTRP2	11.465	33.9314	-4.4615	21.234

Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
ETK-1	GDSC1	-2.7863	-0.278	-2.7923	80.6332
TGBC24TKB	GDSC1	2.5159	9.8247	-0.2259	33.6376
TGBC1TKB	GDSC1	4.6882	12.5656	0.2763	23.1628

Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Endometrium Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
AN3-CA	GDSC1	-2.1305	3.149	-2.4787	67.5342
JHUEM-2	CTRP2; CTRP1	-0.0967	5.6189	-0.7299	36.1636
RL95-2	CTRP2	0.1886	13.039	-3.478	40.1249
MFE-296	GDSC1	0.3372	8.4943	-1.7312	47.9274
MFE-319	GDSC1	0.4638	4.0683	0.122	45.143
KLE	GDSC1	1.104	3.6011	0.9388	37.1121
HEC-151	CTRP2; CTRP1	2.4195	5.4963	2.0481	20.2285
ESS-1	GDSC1	2.4423	3.4117	2.4172	19.6303
JHUEM-7	CTRP2	2.7121	12.2163	-0.6319	27.2807
EN	GDSC1	2.8933	7.7761	1.1255	25.8023
MFE-319	CTRP1	2.9131	4.9936	2.7346	31.9069
RL95-2	CTRP2	3.5702	7.6215	2.3876	14.3737
JHUEM-2	CTRP2; CTRP1	3.5747	6.1221	3.0622	11.7707
HEC-265	CTRP2; CTRP1	3.7006	4.6865	3.6591	9.1819
HEC-6	CTRP2; CTRP1	4.1182	7.7906	2.8472	11.2735
MFE-296	CTRP2	4.1617	7.9557	2.8006	11.2827
MFE-280	GDSC1	4.1737	6.3179	2.9824	7.415
HEC-108	CTRP2; CTRP1	4.2272	8.9464	2.3849	12.9234
HEC-1-A	CTRP2	4.2652	5.6574	3.9734	6.274
JHUEM-1	CTRP2	4.3447	10.9198	1.505	17.1994
HEC-59	CTRP2; CTRP1	4.4006	6.0971	3.9245	6.2061
MFE-319	CTRP2; CTRP1	4.6134	6.5645	3.9089	5.7629
KLE	CTRP2; CTRP1	4.6676	7.7214	3.389	7.8049
ESS-1	CTRP2	4.7274	8.323	3.134	8.6624
HEC-59	CTRP2; CTRP1	4.8585	5.9055	4.4589	2.9346
JHUEM-3	CTRP2	4.884	6.9041	3.9778	4.8029
HEC-1-B	CTRP2	4.9174	6.8141	4.0516	4.4249
HEC-6	CTRP2; CTRP1	4.9552	6.2892	4.3553	3.1609
HEC-151	CTRP2; CTRP1	4.9978	9.338	2.8682	9.3108
HEC-251	CTRP2; CTRP1	5.0496	6.3226	4.4193	2.7039
AN3-CA	CTRP2	5.131	13.6767	0.8002	17.1448
HEC-251	CTRP2; CTRP1	5.1478	7.8222	3.7506	5.3246
EFE-184	CTRP2	5.6023	8.7917	3.613	5.38
EFE-184	CTRP2	5.7017	7.2024	4.4516	1.4722
HEC-265	CTRP2; CTRP1	5.7503	7.0493	4.5637	1.0642
HEC-108	CTRP2; CTRP1	5.7707	10.4405	2.9359	7.6248
HEC-1-B	CTRP2	6.0045	15.106	0.7896	15.5371
KLE	CTRP2; CTRP1	6.1934	17.5181	-0.2523	18.7492
HEC-50B	CTRP2	6.6598	19.4216	-0.8463	24.0545
EN	CTRP2	7.5473	16.7959	1.1012	11.8878
HEC-50B	CTRP2	7.8884	22.593	-1.4872	19.4379
Ishikawa (Heraklio) 02 ER-	CTRP2; CTRP1	3.976	5.1027	3.8649	7.5972
Ishikawa (Heraklio) 02 ER-	CTRP2; CTRP1	4.6481	11.4984	1.4907	15.6048

Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Kidney Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
786-O	GDSC1	-3.1515	1.8921	-3.3466	75.5663
VMRC-RCW	GDSC1	-2.8013	5.0965	-3.7484	67.0514
ACHN	GDSC1	-0.2173	9.7213	-2.8439	51.1283
HA7-RCC	GDSC1	0.186	7.7258	-1.5494	48.7805
UO-31	CTRP2	0.3321	4.7002	-0.0086	32.5031
BB65-RCC	GDSC1	0.9546	7.0656	-0.4702	42.6901
UO-31	GDSC1	1.0128	11.1392	-2.2866	44.8441
LB2241-RCC	GDSC1	1.5664	4.9369	1.0401	33.4875
VMRC-RCZ	GDSC1	1.5767	9.514	-0.9678	40.1976
SW13	GDSC1	1.8469	3.8395	1.692	27.905
769-P	GDSC1	1.8807	6.0599	0.9209	32.1823
BFTC-909	GDSC1	2.2358	6.8544	0.9268	30.1682
TK-10	GDSC1	2.3496	7.4566	0.7581	30.4151
LB996-RCC	GDSC1	2.5302	7.955	0.6952	29.8079
RCC10RGB	GDSC1	2.6497	4.4911	2.3682	18.7817
LB1047-RCC	GDSC1	2.678	7.0361	1.2765	25.9593
SN12C	GDSC1	2.9045	5.5518	2.1925	18.7432
A-704	GDSC1	2.9219	3.9502	2.8367	14.033
SW156	GDSC1	2.9263	8.9184	0.5973	28.4071
CAL-54	GDSC1	3.2919	8.6819	1.0456	24.4681
OS-RC-2	GDSC1	3.8861	16.7658	-2.478	34.5433
KMRC-3	CTRP2	4.2279	21.1133	-3.6802	30.7817
TUHR10TKB	CTRP2	4.6142	5.889	4.2259	5.9602
Caki-2	CTRP2	4.6389	6.1067	4.1464	4.6377
RCC10RGB	CTRP1	4.7621	5.443	4.5856	5.6774
RXF 393L	GDSC1	4.8098	9.8525	1.7181	14.6572
A-498	CTRP2	4.8637	6.3751	4.2231	3.8177
VMRC-RCW	CTRP2; CTRP1	4.9261	7.8513	3.5505	6.5949
VMRC-RCZ	CTRP2	5.0816	9.2127	2.9911	8.5549
SNU-1272	CTRP2	5.1092	6.194	4.5226	2.0714
SNU-1272	CTRP2	5.118	6.2419	4.5058	2.1258
TUHR10TKB	CTRP2	5.1626	6.1553	4.5841	1.7185
A-498	GDSC1	5.3558	6.7532	3.5225	0.8912
BFTC-909	CTRP2	5.3732	8.6251	3.5201	5.7996
TUHR14TKB	CTRP2	5.5322	16.4117	-0.238	31.5647
VMRC-RCW	CTRP2; CTRP1	5.6138	15.4493	0.3186	19.0005
769-P	CTRP2	5.6706	9.9916	3.0713	7.1562
769-P	CTRP2	5.7242	7.6216	4.2688	2.1578
TUHR4TKB	CTRP2	5.7323	12.1691	2.0378	11.2793
CAL-54	CTRP2	5.7467	19.1198	-1.4169	22.8766
OS-RC-2	CTRP2	5.9222	7.9012	4.2644	1.9211
KMRC-20	CTRP2	6.0465	9.7476	3.4665	4.9289
Caki-1	GDSC1	6.188	13.3601	0.994	15.0955
BFTC-909	CTRP2	6.3987	7.9828	4.4916	0.6829
KMRC-1	GDSC1	6.6119	13.8925	1.0245	13.8715
OS-RC-2	CTRP2	6.8463	13.7841	2.0699	9.3217
KMRC-2	CTRP2	6.934	12.9093	2.5534	7.2998
KMRC-1	CTRP2	7.0508	11.4904	3.3005	4.2393
Caki-1	CTRP2	7.5465	13.3096	2.7643	5.6722
RCC10RGB	CTRP2; CTRP1	7.7319	15.8806	1.681	9.5752
786-O	CTRP2	7.7693	14.4581	2.3685	6.8878
KMRC-20	GDSC1	8.4405	23.1142	-2.1574	22.5944
KMRC-20	CTRP2	9.8246	22.3456	-0.0205	12.4777
ACHN	CTRP2	9.9962	21.5163	0.4786	10.7074

Cancer Drug Sensitivity Data Curated from 133 Cell Line(s) in Large Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SNU-81	CTRP2; CTRP1	-4.0621	9.8733	-6.526	55.6689
KM12	GDSC1	-3.2545	4.6509	-4.104	69.5479
SW48	CTRP2; CTRP1	-2.3828	4.2103	-2.8475	49.6011
HCT 15	GDSC1	-2.3093	6.0147	-3.5246	63.6418
LoVo	GDSC1	-2.0901	5.2665	-3.0307	63.6647
CCK-81	CTRP2	-1.4281	5.9243	-2.2777	44.4562
HCC2998	GDSC1	-1.1597	2.9441	-1.3818	61.311
T84	GDSC1	-0.927	5.9484	-2.0114	56.5067
LS180	GDSC1	-0.8182	6.8865	-2.2544	55.2562
LS411N	GDSC1	-0.7961	4.3297	-1.3278	56.8806
LoVo	CTRP2; CTRP1	-0.7469	9.5918	-2.9062	44.5786
HT-29	GDSC1	-0.5586	6.8152	-1.9508	53.7234
RKO	GDSC1	-0.4192	3.7238	-0.7503	54.1117
GP5d	GDSC1	-0.3353	8.1143	-2.256	52.0016
SNU-175	CTRP2; CTRP1	-0.2897	10.0958	-2.6425	40.5729
SW948	CTRP1	-0.1306	17.7343	-5.9926	55.0987
SW620	GDSC1	-0.0753	6.2076	-1.1981	50.5681
SW626	GDSC1	0.2828	6.7756	-1.0473	47.9174
NCI-H747	GDSC1	0.285	5.3616	-0.4934	47.5106
LS1034	GDSC1	0.7484	9.1658	-1.6205	45.5274
CW-2	CTRP2; CTRP1	0.8992	13.8585	-3.1534	44.6692
GP2d	CTRP1	0.9149	13.3269	-2.8876	52.7585
SW1116	CTRP2	1.2581	11.5888	-1.7446	41.845
SW948	CTRP2; CTRP1	1.412	15.2929	-3.3436	36.5828
LS123	GDSC1	1.5304	6.5082	0.3654	36.7135
SW48	CTRP2; CTRP1	1.7932	4.2123	1.6853	22.1032
CL-34	CTRP2; CTRP1	1.8745	23.1062	-6.7389	39.4861
COLO205	GDSC1	1.9741	2.885	1.9679	25.3624
T84	CTRP2	2.1507	10.9121	-0.5489	28.5216
HCT 116	GDSC1	2.1875	7.0591	0.7842	31.1413
LS513	CTRP2; CTRP1	2.237	7.3769	1.1396	22.774
GP2d	CTRP2; CTRP1	2.2451	25.7081	-7.6952	39.5809
SNU-407	CTRP2	2.2574	10.6039	-0.2994	29.1478
KM12	CTRP2; CTRP1	2.2977	6.3227	1.6259	20.8023
SW48	GDSC1	2.5233	6.1584	1.5333	25.1612
HT115	CTRP2; CTRP1	2.575	10.9859	-0.164	26.299
SK-CO-1	CTRP2; CTRP1	2.6973	6.8807	1.8281	18.9217
SNU-61	CTRP2; CTRP1	2.7005	9.1814	0.8088	24.2245
COLO 320	CTRP1	2.7756	22.3633	-5.5627	46.6361
NCI-H747	CTRP2	2.8255	8.4656	1.2567	20.6781
COLO 320HSR	GDSC1	3.0085	12.2457	-0.9757	33.8982
SNU-C2B	GDSC1	3.2283	13.5299	-1.4224	34.2783
MDST8	GDSC1	3.2824	10.8867	-0.0582	29.7256
CW-2	CTRP2; CTRP1	3.3834	7.6349	2.2022	15.6604
CCK-81	GDSC1	3.4155	9.0581	0.9687	24.3707
COLO205	CTRP2; CTRP1	3.425	8.566	1.8092	17.1113
SNU-175	CTRP1	3.4512	5.7853	3.0636	25.8927
CCK-81	CTRP2	3.4746	5.6235	3.1443	11.6508
LoVo	CTRP2; CTRP1	3.4922	7.1597	2.5276	14.0916
CL-11	CTRP2	3.5095	12.1016	0.1671	22.8519
SNU-C4	CTRP1	3.5976	13.2074	-0.2892	39.0999
LS411N	CTRP2; CTRP1	3.6874	6.4198	3.0542	11.5007
CaR-1	GDSC1	3.7725	11.1913	0.2131	26.6752
SW1463	GDSC1	3.7733	12.0498	-0.2153	28.446
SNU-1033	CTRP2	3.7904	18.404	-2.7072	29.8129
KM12	CTRP2; CTRP1	3.8105	9.1773	1.8851	15.89
LS123	CTRP2; CTRP1	3.8191	7.9085	2.5038	13.3792
SNU-C5	CTRP2; CTRP1	3.8269	15.9794	-1.4593	28.2501
SW403	CTRP1	3.8525	6.1305	3.3494	21.2029
LS513	CTRP2; CTRP1	3.9427	6.1877	3.4182	9.3958
HT115	CTRP2; CTRP1	3.9489	6.8822	3.1127	10.5989
HCT 15	CTRP2	3.953	10.1592	1.5289	16.892
COLO 320	CTRP2; CTRP1	3.9891	11.4418	0.9372	19.1219
SNU-407	CTRP2	4.0353	6.0404	3.5718	8.4608
HCT 116	CTRP2; CTRP1	4.0382	7.9282	2.7048	12.0427
SNU-81	CTRP1	4.0675	7.9027	2.745	24.5719
DLD-1	CTRP2; CTRP1	4.0797	5.7851	3.7313	7.8055
SNU-C4	CTRP2; CTRP1	4.1733	5.0816	4.0862	6.1993
SW1417	GDSC1	4.1875	6.7866	2.7597	9.1091
SW1417	CTRP2	4.2201	10.8373	1.4353	16.6604
SNU-C5	CTRP2; CTRP1	4.2814	6.9217	3.4204	8.5423
C2BBe1	CTRP1	4.3075	5.9192	3.9105	13.9458
LS180	CTRP2; CTRP1	4.3284	9.2694	2.3177	12.9756
C2BBe1	GDSC1	4.3292	9.2424	1.6478	16.7262
NCI-H508	CTRP2; CTRP1	4.3652	11.1619	1.4116	16.5093
HT-55	CTRP2; CTRP1	4.3903	12.84	0.598	20.6559
NCI-H716	GDSC1	4.391	6.205	3.2039	4.9959
SNU-61	CTRP2; CTRP1	4.4178	6.6446	3.6842	7.1406
NCI-H716	CTRP2	4.4352	10.6105	1.7387	15.0062
SNU-1040	CTRP1	4.4425	5.1651	4.3545	9.4761
LS513	GDSC1	4.4481	7.7228	2.4976	10.2578
LS123	CTRP2; CTRP1	4.4754	10.1339	2.0201	14.8266
DLD-1	CTRP2; CTRP1	4.5064	8.2963	2.9594	9.9402
SW837	GDSC1	4.5128	12.5451	0.1469	24.333
CL-34	CTRP1	4.5229	11.8491	1.2074	30.5947
SNU-1040	CTRP1	4.5637	5.1981	4.4749	7.7566
HCT 8	CTRP2; CTRP1	4.5834	5.2862	4.464	3.5987
C2BBe1	CTRP2; CTRP1	4.5885	5.2389	4.4872	3.4965
SW403	CTRP1	4.6003	6.153	4.0947	10.7937
LS1034	CTRP2	4.6172	5.2679	4.5025	3.2648
COLO205	CTRP2; CTRP1	4.7134	7.3385	3.6198	6.7441
HT-55	CTRP2; CTRP1	4.7139	7.0438	3.7661	6.1328
SW620	CTRP2; CTRP1	4.7217	7.5087	3.5427	7.0482
RCM-1 [Human ESC]	CTRP1	4.7375	13.2972	0.669	31.7032
SW1116	CTRP2	4.7718	6.6077	4.0253	4.8404
HCC-56	CTRP2	4.8059	5.6032	4.5478	2.5982
COLO 678	CTRP1	4.9114	16.4472	-0.7587	35.0558
COLO201	CTRP2	4.9536	11.0681	1.9566	13.0686
RKO	CTRP2; CTRP1	4.9687	7.6758	3.6746	5.9892
COLO 678	GDSC1	5.0129	20.0646	-3.2046	32.9053
NCI-H508	CTRP2; CTRP1	5.0239	9.0858	3.0163	8.6415
MDST8	CTRP2; CTRP1	5.096	7.1779	4.0301	4.249
CL-11	CTRP2	5.1168	8.4765	3.3883	6.8219
OUMS-23	CTRP2	5.1355	7.1336	4.0748	3.9032
LS411N	CTRP2; CTRP1	5.1574	7.2671	4.0357	4.1104
OUMS-23	CTRP2	5.1643	6.1005	4.6126	1.5962
SNU-C2A	CTRP2; CTRP1	5.1859	8.1066	3.6395	5.7198
RCM-1 [Human ESC]	GDSC1	5.2105	8.9134	2.4642	8.2776
HT115	GDSC1	5.326	7.4475	3.2156	2.7238
LS180	CTRP2; CTRP1	5.3269	7.9108	3.8497	4.584
RCM-1 [Human ESC]	CTRP2; CTRP1	5.3302	9.4005	3.1098	7.6732
SK-CO-1	CTRP2; CTRP1	5.3404	7.4577	4.0853	3.5768
COLO201	CTRP2	5.362	6.7876	4.4212	2.0666
CL-11	GDSC1	5.3651	8.0028	2.9894	4.1683
CL-40	CTRP1	5.5042	8.2509	3.8171	9.4334
HT-29	CTRP2; CTRP1	5.6251	7.0965	4.4644	1.5923
HT-55	GDSC1	5.6969	7.5208	3.3725	1.2634
SW480	CTRP1	5.8237	10.5826	2.9056	15.6175
MDST8	CTRP2; CTRP1	5.8347	10.1318	3.1364	7.1648
CL-40	CTRP1	5.8367	10.7673	2.8241	16.1576
SNU-C1	GDSC1	5.9748	7.8912	3.3513	1.0777
SW480	CTRP1	6.0088	14.0072	1.3496	24.1537
SW620	CTRP2; CTRP1	6.0388	16.4807	0.1427	18.7621
SW948	GDSC1	6.0859	7.806	3.4306	0.6588
HT-29	CTRP2; CTRP1	6.1393	14.0828	1.4127	13.0726
SNU-503	CTRP2	6.2466	15.5462	0.7587	15.218
CW-2	GDSC1	6.4503	7.9622	3.5133	0.241
HCT 116	CTRP2; CTRP1	6.6417	13.624	2.0131	9.9287
HCT 8	CTRP1	7.1699	19.0733	-0.2763	26.8208
SNU-C2A	CTRP2; CTRP1	7.1915	22.9586	-2.1818	22.3503
COLO 678	CTRP2; CTRP1	7.329	19.1703	-0.2059	16.6775
SNU-C1	CTRP2	7.8015	22.6296	-1.5696	19.7904
RKO	CTRP2; CTRP1	8.5102	17.8035	1.2823	9.9533

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MO-T	GDSC1	4.7924	9.3948	1.9311	13.2714

Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Liver Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SNU-398	GDSC1	-4.8019	1.2479	-5.0183	82.1713
HLE	GDSC1	-1.6516	3.6384	-2.0729	63.7651
SNU-449	GDSC1	-1.3162	0.9703	-1.3287	65.58
SK-HEP-1	GDSC1	-1.2482	3.5746	-1.6172	61.1158
Hep 3B2.1-7	GDSC1	-0.9564	2.3096	-1.0587	60.35
SNU-423	GDSC1	-0.3958	4.4484	-0.9268	53.5565
JHH-7	GDSC1	-0.3302	4.5944	-0.9004	52.9385
SNU-398	CTRP2; CTRP1	0.9397	15.6634	-3.973	38.6979
JHH-4	GDSC1	0.9429	4.0167	0.6591	39.5743
SNU-182	CTRP2	1.5429	9.947	-0.7067	30.6799
Hep-G2/C3A	GDSC1	1.8951	8.1221	0.0001	35.9293
JHH-1	GDSC1	2.0918	3.9649	1.927	24.9238
JHH-5	CTRP2	2.303	6.8342	1.4269	22.9612
SNU-387	GDSC1	2.494	4.3536	2.2479	20.4697
Huh-7	GDSC1	2.5125	4.5256	2.2079	20.6458
SNU-886	CTRP2	2.6103	21.6938	-5.3867	41.5248
SNU-398	CTRP2; CTRP1	3.0779	8.0154	1.7221	18.3224
JHH-6	GDSC1	3.3244	9.6503	0.5938	26.6936
HuH-1	GDSC1	3.3737	9.1653	0.8785	25.0344
SNU-449	CTRP1	3.6752	5.5797	3.3803	22.0318
SNU-761	CTRP2	3.6778	13.7762	-0.5069	24.5792
Li-7	CTRP2	4.0459	13.9655	-0.2733	23.0367
SNU-449	CTRP2; CTRP1	4.0817	5.3637	3.896	7.1708
Hep-G2	CTRP2; CTRP1	4.2682	6.3593	3.6718	8.0917
SNU-761	CTRP2	4.3888	7.8702	3.0538	9.7234
HLF	CTRP2	4.4601	10.1798	1.9749	14.0084
JHH-1	CTRP2	4.4698	11.6364	1.2581	16.8014
HuH-6	CTRP2	4.6225	7.2116	3.5919	6.9717
Li-7	CTRP2	4.6395	9.0397	2.7001	10.6552
Hep 3B2.1-7	CTRP2	4.6583	7.4666	3.4982	7.2849
SNU-878	CTRP2	4.6778	11.5591	1.4767	15.5256
SNU-878	CTRP2	4.7226	7.0243	3.775	5.9912
JHH-6	CTRP1	4.7663	5.1951	4.6943	4.7408
SNU-387	CTRP2	4.9076	8.6365	3.1331	8.3003
JHH-2	GDSC1	4.931	15.368	-0.928	27.1916
JHH-6	CTRP2; CTRP1	5.0527	5.7568	4.7048	1.499
Hep-G2	CTRP2; CTRP1	5.1405	6.3379	4.486	2.2528
Hep 3B2.1-7	CTRP2	5.218	6.4558	4.4777	2.0675
SNU-475	CTRP2	5.2261	7.6834	3.8731	4.5836
SNU-886	CTRP2	5.525	10.2877	2.8117	8.4858
SNU-475	GDSC1	5.5917	9.7971	2.2964	8.4877
JHH-2	CTRP2	5.5953	13.5049	1.2641	14.5422
HuH-1	CTRP2	6.3536	18.4954	-0.6236	19.5423
SNU-423	CTRP2	6.767	13.825	1.9937	9.7391
PLC/PRF/5	CTRP2	7.3564	15.5007	1.5951	10.3676
JHH-4	CTRP2	7.7733	19.7128	-0.1586	15.7744
SK-HEP-1	CTRP2	7.785	16.1291	1.5861	9.7849

Cancer Drug Sensitivity Data Curated from 452 Cell Line(s) in Lung Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H847	GDSC1	-6.6048	6.1815	-8.2349	74.9522
NCI-H2369	GDSC1	-6.1536	-2.7558	-6.1579	95.7383
IA-LM	GDSC1	-3.8378	5.4315	-4.9834	70.0693
NCI-H3122	GDSC1	-3.5139	2.988	-3.9476	74.0081
SBC-3	GDSC1	-2.462	3.1572	-2.8412	69.263
NCI-H2122	GDSC1	-2.4317	3.4411	-2.8747	68.5059
NCI-H2009	GDSC1	-1.557	2.9681	-1.8171	64.2794
NCI-H2342	GDSC1	-1.5502	2.1916	-1.6763	65.6478
NCI-H1355	GDSC1	-1.3723	5.6459	-2.3826	59.4269
NCI-H1341	CTRP2	-1.3344	5.5559	-2.0632	43.7732
NCI-H1299	GDSC1	-1.065	2.5474	-1.2095	61.048
NCI-H1568	CTRP1	-1.0408	6.8696	-2.1675	66.1922
DMS 273	GDSC1	-0.8252	2.0447	-0.8886	59.3395
CAL-12T	GDSC1	-0.5607	5.199	-1.3495	54.4954
NCI-H1963	CTRP1	-0.5156	11.2557	-3.3789	59.2464
NCI-H2795	GDSC1	-0.3755	7.7075	-2.1247	52.3253
LC-2/ad	GDSC1	-0.3403	3.1268	-0.53	53.6249
NCI-H727	GDSC1	-0.2627	4.0615	-0.669	52.5219
NCI-H1568	GDSC1	-0.2552	6.3618	-1.4498	51.8533
LK-2	GDSC1	-0.2403	6.5339	-1.5017	51.7141
A-427	GDSC1	-0.2298	3.2909	-0.4437	52.4344
HCC44	GDSC1	-0.1417	3.5489	-0.4052	51.4709
NCI-H211	CTRP2	-0.0974	12.8771	-3.6892	41.2344
NCI-H1975	GDSC1	-0.0942	9.5516	-2.6428	50.5022
EBC-1	GDSC1	-0.0769	8.0035	-1.9409	50.4769
SW1271	GDSC1	-0.0763	4.0148	-0.4526	50.754
NCI-H524	CTRP2	0.075	6.6943	-0.9045	38.2049
LCLC-103H	GDSC1	0.0914	7.4138	-1.5142	49.3862
NCI-H810	GDSC1	0.1981	6.7267	-1.1162	48.5465
SK-MES-1	GDSC1	0.2646	4.7935	-0.3179	47.5247
Calu-6	GDSC1	0.3087	4.4446	-0.1581	46.9672
NCI-H522	GDSC1	0.41	4.3235	-0.0107	45.8621
NCI-H1944	GDSC1	0.4475	11.8414	-3.1679	47.9448
NCI-H1105	CTRP2; CTRP1	0.5705	11.546	-2.4051	37.4223
NCI-H650	GDSC1	0.5889	11.0764	-2.6685	47.0872
ChaGo-K-1	GDSC1	0.6192	4.2135	0.2499	43.5183
NCI-H1915	GDSC1	0.6587	13.9148	-3.958	47.3686
NCI-H596	GDSC1	0.7451	10.4436	-2.2178	46.0545
COR-L279	CTRP1	0.7753	7.6486	-0.5108	55.6579
NCI-H520	GDSC1	0.7848	6.52	-0.415	43.7032
NCI-H1105	CTRP1	0.8069	11.0961	-1.9629	53.8303
LCLC-97TM1	GDSC1	0.9343	5.2998	0.2272	41.1412
NCI-H1648	GDSC1	0.9951	8.2479	-0.9539	43.3035
SCLC-21H	CTRP1	1.1499	9.0274	-0.6934	52.6428
NCI-H2087	GDSC1	1.1615	10.21	-1.7009	43.4898
NCI-H2087	CTRP2	1.2297	14.0589	-2.9349	36.3751
NCI-H2869	GDSC1	1.2457	5.8918	0.3277	38.66
ABC-1	GDSC1	1.2596	9.664	-1.3474	42.4961
NCI-H1963	CTRP1	1.3324	7.0802	0.3046	51.8897
NCI-H441	GDSC1	1.3354	7.5023	-0.2735	39.8989
NCI-H2030	GDSC1	1.3544	5.4919	0.6026	36.9028
SBC-5	GDSC1	1.3906	4.7579	0.9144	35.2638
NCI-H2228	GDSC1	1.4296	9.5701	-1.1373	41.2748
Lu-135	GDSC1	1.4331	6.5219	0.259	37.6968
NCI-H596	CTRP1	1.4643	20.8587	-6.0057	50.2644
NCI-H82	CTRP1	1.4779	5.8345	0.9146	50.8162
SCLC-21H	CTRP1	1.4888	7.157	0.4408	50.5913
NCI-H2110	GDSC1	1.5226	7.8452	-0.2406	38.7257
NCI-H1568	CTRP2; CTRP1	1.5311	6.6346	0.6875	26.4315
NCI-H146	CTRP2	1.568	8.1336	0.1175	28.1577
NCI-H460	GDSC1	1.5747	12.5407	-2.4285	42.5617
Lu-99	CTRP2; CTRP1	1.6009	7.575	0.3907	27.2317
NCI-H23	CTRP1	1.6321	7.4418	0.478	49.3917
DMS 273	CTRP1	1.6478	6.3426	0.9209	49.1408
COLO 668	GDSC1	1.7644	6.3573	0.672	34.0473
NCI-H1693	CTRP2	1.794	6.3664	1.065	24.2458
NCI-H2196	CTRP2	1.8313	6.3815	1.0995	24.0119
LXF 289	GDSC1	1.8324	7.0445	0.4354	34.6596
NCI-H446	CTRP2	1.9256	11.5209	-1.0557	38.1042
Calu-3	GDSC1	1.9606	13.7571	-2.6674	41.3545
NCI-H1581	CTRP2	1.984	9.2507	0.0534	27.1592
EBC-1	CTRP2; CTRP1	1.995	11.8021	-1.1138	32.202
NCI-H810	CTRP1	2.0001	6.9801	1.053	45.92
SK-LU-1	GDSC1	2.015	4.8025	1.5717	27.6865
NCI-H211	GDSC1	2.0849	25.4081	-8.3391	45.162
NCI-H1944	CTRP1	2.1129	9.8824	-0.0992	46.3785
NCI-H1734	CTRP2	2.1254	10.0672	-0.1791	27.4923
NCI-H1666	CTRP2; CTRP1	2.1263	10.1792	-0.2232	27.6854
Lu-99A	GDSC1	2.1533	12.1966	-1.7234	39.0885
VMRC-LCD	CTRP1	2.1675	6.6821	1.3486	44.0046
COR-L105	GDSC1	2.1698	4.5461	1.8307	25.1175
Calu-6	CTRP2; CTRP1	2.1874	4.7574	2.002	21.1611
NCI-H1048	CTRP1	2.1934	5.3417	1.8501	42.4201
HOP-62	GDSC1	2.2585	6.9265	0.9161	30.1026
COLO 668	CTRP1	2.2849	9.8361	0.0931	45.1449
HCC15	GDSC1	2.2959	7.2833	0.787	30.5528
RERF-LC-KJ	GDSC1	2.2961	10.4773	-0.749	36.2434
NCI-H2135	GDSC1	2.3044	9.2491	-0.1437	34.347
PaCa-3	GDSC1	2.3133	13.348	-2.1447	39.22
NCI-H2085	GDSC1	2.337	6.436	1.2197	28.033
NCI-H358	GDSC1	2.393	5.8879	1.5228	25.9071
NCI-H3255	GDSC1	2.4383	10.1848	-0.474	34.8
NCI-H1437	GDSC1	2.4608	6.7625	1.1927	27.5406
KNS-62	CTRP1	2.4678	13.1627	-1.3132	45.5335
NCI-H2106	CTRP2	2.4882	10.835	-0.1835	26.5268
NCI-H1703	CTRP2	2.5045	14.2493	-1.8149	30.843
COR-L47	CTRP2	2.5312	13.9768	-1.657	30.4102
NCI-H2029	CTRP1	2.5402	5.2209	2.2643	37.6231
SHP-77	CTRP2; CTRP1	2.5412	5.8984	2.0436	18.5445
BEN	GDSC1	2.5589	4.8539	2.1331	20.9205
NCI-H1876	CTRP1	2.5613	12.8723	-1.0842	44.9112
NCI-H526	CTRP2	2.5964	10.0786	0.2795	24.7546
ChaGo-K-1	CTRP1	2.6656	4.7655	2.5208	35.1511
COR-L23	GDSC1	2.6921	4.5576	2.3893	18.4047
DMS 454	CTRP2	2.7006	6.0437	2.1579	17.5802
NCI-H2347	GDSC1	2.7187	8.525	0.5975	29.3645
NCI-H1975	CTRP2; CTRP1	2.7459	9.5507	0.6812	23.0529
NCI-H2405	GDSC1	2.7622	7.5621	1.1054	26.5365
HOP-92	GDSC1	2.7801	12.7924	-1.4501	36.0161
NCI-H1734	GDSC1	2.8038	10.0355	-0.0647	31.767
IST-SL2	GDSC1	2.8261	9.3091	0.3133	30.1478
NCI-H520	CTRP2	2.8349	9.1631	0.9432	21.8138
NCI-H2170	GDSC1	2.9113	15.1313	-2.497	37.6964
NCI-H2722	GDSC1	2.9147	10.4452	-0.1665	31.6645
EPLC-272H	CTRP2; CTRP1	2.9417	12.2668	-0.4323	26.1766
NCI-H1930	CTRP1	2.9486	4.7054	2.8418	30.908
NCI-H661	GDSC1	2.953	9.0968	0.5339	28.5871
PC-14	GDSC1	3.0173	9.235	0.5243	28.346
COR-L51	CTRP1	3.0302	6.6873	2.2572	33.9678
NCI-H1563	GDSC1	3.0561	8.2715	1.0344	25.5673
NCI-H2803	GDSC1	3.0602	10.7867	-0.2052	31.194
NCI-H2087	CTRP2	3.0738	7.2168	2.0696	16.9011
NCI-H2171	GDSC1	3.0757	20.2907	-4.9279	40.5078
COLO 668	CTRP2; CTRP1	3.0765	7.1294	2.1165	16.7893
NCI-H358	CTRP2; CTRP1	3.0871	6.9598	2.2009	16.4326
LC-1/sq	GDSC1	3.0969	8.6359	0.8923	26.156
NCI-H2405	CTRP2; CTRP1	3.1035	11.416	0.1331	24.0086
NCI-H292	GDSC1	3.1067	9.2129	0.6162	27.515
NCI-H82	GDSC1	3.1099	5.4521	2.4439	15.9114
NCI-H2081	CTRP1	3.1205	7.9953	1.7739	35.6651
LXF 289	CTRP2; CTRP1	3.1313	5.9682	2.6521	15.6094
Calu-3	CTRP2; CTRP1	3.1447	10.2571	0.732	21.8601
NCI-H1048	CTRP1	3.1447	4.2362	3.124	27.4925
NCI-H64	GDSC1	3.1664	8.2418	1.1498	24.4225
SW1271	CTRP2	3.174	9.3482	1.1873	20.0511
HCC78	GDSC1	3.193	8.1897	1.1997	24.0149
A-549	GDSC1	3.2065	8.2169	1.1985	23.9624
DMS 79	CTRP2	3.21	13.5654	-0.8271	26.6035
NCI-H810	CTRP2; CTRP1	3.2204	13.1738	-0.6169	26.0356
NCI-H1048	GDSC1	3.2388	4.7098	2.907	11.8426
NCI-H1666	CTRP2; CTRP1	3.2514	6.1283	2.718	13.9844
DV-90	CTRP2; CTRP1	3.2533	9.475	1.2109	19.8383
EPLC-272H	GDSC1	3.2601	8.4448	1.1344	24.101
DMS 273	CTRP2; CTRP1	3.2696	5.5022	2.9693	12.9818
NCI-H2172	GDSC1	3.2986	9.8312	0.4811	27.3398
NCI-H1694	CTRP2; CTRP1	3.3068	6.4491	2.646	14.1114
NCI-H82	CTRP1	3.3071	4.9492	3.1759	25.9929
NCI-H841	CTRP2; CTRP1	3.3456	7.0367	2.4333	14.8424
NCI-H1092	CTRP2	3.3636	7.1512	2.3947	14.8679
COR-L279	CTRP1	3.4012	5.0352	3.2563	24.7569
SHP-77	GDSC1	3.4232	9.0829	0.9632	24.3687
HCC1833	CTRP2; CTRP1	3.4297	16.5444	-2.0924	29.3243
NCI-H2023	GDSC1	3.4342	10.0056	0.5136	26.6261
DMS 53	CTRP2	3.4345	5.8534	3.0153	12.2539
NCI-H1155	CTRP2	3.4348	8.9415	1.6331	17.7019
NCI-H1688	GDSC1	3.4419	4.3967	3.2504	8.3038
SHP-77	CTRP2; CTRP1	3.476	5.8097	3.0809	11.9715
NCI-H889	CTRP2	3.476	10.0956	1.1166	25.8395
NCI-H1355	CTRP2; CTRP1	3.4789	7.0314	2.5716	13.951
NCI-H1573	CTRP2; CTRP1	3.482	6.67	2.734	13.3011
NCI-H2804	GDSC1	3.4839	6.821	2.1392	16.521
NCI-H226	GDSC1	3.5065	10.4595	0.3503	27.0951
NCI-H1781	GDSC1	3.5175	11.2777	-0.0484	28.755
SBC-1	GDSC1	3.5228	9.2797	0.9526	24.0154
SK-MES-1	CTRP2	3.5236	10.6232	0.9046	20.2488
NCI-H2029	CTRP2; CTRP1	3.5297	4.915	3.427	10.5337
Ms-1	GDSC1	3.5429	15.6755	-2.2229	35.0748
NCI-H2731	GDSC1	3.5618	12.301	-0.5211	30.3532
COR-L88	GDSC1	3.5757	5.7686	2.7413	11.5724
NCI-H1770	GDSC1	3.6462	15.5009	-2.0479	34.357
LCLC-97TM1	CTRP2; CTRP1	3.6494	10.3378	1.1691	19.0423
NCI-H290	GDSC1	3.653	7.5124	1.9469	17.215
NCI-H1694	CTRP1	3.6565	10.4703	1.1109	35.102
CPC-N	GDSC1	3.6762	11.949	-0.2475	28.9297
HARA [Human squamous cell lung carcinoma]	GDSC1	3.6834	14.8084	-1.6702	33.3319
LXF 289	CTRP2; CTRP1	3.6951	4.7362	3.6446	9.2495
COR-L88	CTRP1	3.6962	5.2725	3.5084	20.8901
NCI-H1703	GDSC1	3.7069	8.8379	1.3326	21.0658
LC-1/sq-SF	CTRP1	3.7139	12.9832	-0.0733	38.1316
NCI-H841	GDSC1	3.7162	6.121	2.6946	11.3594
EKVX	GDSC1	3.7315	12.1233	-0.2875	28.8765
NCI-H1944	CTRP2; CTRP1	3.7641	9.2638	1.7993	16.3388
NCI-H1184	CTRP2	3.7732	7.501	2.6442	13.7545
NCI-H2081	CTRP2; CTRP1	3.7896	6.8718	2.9579	11.6195
Lu-99	CTRP2; CTRP1	3.7976	6.5029	3.1313	10.9083
NCI-H2342	CTRP1	3.8113	6.3833	3.1978	22.6499
NCI-H1299	CTRP2; CTRP1	3.814	10.2745	1.3527	17.9631
Calu-6	CTRP2; CTRP1	3.8207	5.0066	3.7216	8.5858
NCI-H1963	GDSC1	3.8352	13.9265	-1.1012	31.2528
NCI-H661	CTRP2; CTRP1	3.8403	6.619	3.1232	14.7555
NCI-H1355	CTRP2; CTRP1	3.8465	6.0876	3.3612	9.8748
NCI-H2196	GDSC1	3.8494	5.5488	3.0968	7.6876
NCI-H2591	GDSC1	3.9045	20.1003	-4.1298	37.347
LOU-NH91	GDSC1	3.9051	19.1263	-3.6423	36.6112
NCI-H2023	CTRP2; CTRP1	3.912	7.1668	2.9441	12.1804
Lu-139	GDSC1	3.9186	5.6693	3.0966	7.4251
Sq-1	CTRP2; CTRP1	3.9228	7.5138	2.7916	12.8136
NCI-H1299	CTRP2; CTRP1	3.932	5.6245	3.6388	8.5683
NCI-H1755	GDSC1	3.9375	10.2728	0.8113	23.1478
NCI-H209	GDSC1	3.9504	13.5423	-0.8125	29.9494
NCI-H1651	GDSC1	3.9528	7.6299	2.1456	14.6172
COR-L95	CTRP2	3.9622	9.2007	2.0074	14.9741
EKVX	CTRP2	3.9799	6.3789	3.3661	9.4202
NCI-H2444	GDSC1	3.9808	4.7108	3.6284	3.0008
NCI-H596	CTRP1	3.9869	9.3321	1.9743	29.6692
NCI-H1573	CTRP2; CTRP1	3.9939	13.4408	-0.0497	22.5064
NCI-H522	CTRP1	3.9977	8.3419	2.4665	26.7946
COR-L51	CTRP2; CTRP1	4.0009	5.5491	3.7412	7.985
ChaGo-K-1	CTRP2; CTRP1	4.0024	5.3441	3.8171	7.695
NCI-H2122	CTRP2; CTRP1	4.0139	5.7806	3.6639	8.2456
NCI-H69	CTRP2	4.0163	7.5752	2.8455	11.4372
NCI-H2291	CTRP2	4.0187	12.9756	0.1947	21.5901
EBC-1	CTRP2; CTRP1	4.0206	7.8095	2.745	11.9196
NCI-H1373	CTRP2; CTRP1	4.0283	9.0252	2.1627	14.2744
NCI-H1930	CTRP1	4.0348	5.1652	3.9106	15.5693
NCI-H446	CTRP2	4.0474	6.7705	3.2554	9.6949
HCC33	CTRP1	4.0798	16.1727	-1.3337	39.0914
NCI-H1836	CTRP1	4.0815	15.0757	-0.7857	38.1093
NCI-H520	CTRP2	4.0816	8.4094	2.5048	12.6805
NCI-H1435	GDSC1	4.0975	7.5568	2.3022	12.9262
NCI-H1437	CTRP1	4.1011	5.6263	3.8181	15.9055
NCI-H1623	GDSC1	4.1052	7.5031	2.3353	12.6508
NCI-H1869	GDSC1	4.1118	7.0689	2.5577	10.9362
NCI-H647	GDSC1	4.1155	6.3211	2.9343	7.9922
HCC44	CTRP2; CTRP1	4.1364	11.2992	1.1402	18.0406
NCI-H1792	GDSC1	4.1544	12.2581	-0.0011	26.2063
NCI-H1793	CTRP1	4.1613	11.5492	1.0384	32.8842
NCI-H2595	GDSC1	4.1668	14.9892	-1.3562	30.9062
NCI-H2141	CTRP1	4.2107	5.0107	4.1459	12.6
NCI-H23	CTRP2; CTRP1	4.2188	8.4565	2.6177	11.987
NCI-H650	CTRP2; CTRP1	4.2283	10.4318	1.6523	15.8692
NCI-H1435	CTRP2; CTRP1	4.2396	9.3231	2.2107	14.5578
LCLC-103H	CTRP2; CTRP1	4.2423	6.9484	3.3699	8.8418
DMS 114	GDSC1	4.298	7.368	2.5575	10.2963
NCI-H1435	CTRP2; CTRP1	4.3122	6.4551	3.6709	7.4484
NCI-H1915	CTRP1	4.324	7.4813	3.1915	19.8796
NCI-H1693	GDSC1	4.3261	8.4729	2.0291	14.1176
NCI-H1836	CTRP1	4.3368	5.826	3.9815	13.181
NCI-H2085	CTRP2	4.3485	16.3501	-1.1984	30.6572
COR-L88	CTRP1	4.3622	5.194	4.2578	10.7492
NCI-H2286	CTRP2; CTRP1	4.3641	8.1782	2.8881	10.5471
Lu-65	CTRP1	4.3903	9.0764	2.4689	24.7395
HCC2935	CTRP2; CTRP1	4.4269	6.1307	3.9352	6.0979
NCI-H1838	CTRP2	4.4494	7.737	3.1749	9.0866
NCI-H1975	CTRP1	4.4526	5.9847	4.0281	12.146
NCI-H1563	CTRP2	4.4562	5.7699	4.1224	5.1835
NCI-H2122	CTRP2; CTRP1	4.4579	8.5052	2.8125	10.6551
COLO 699	CTRP2; CTRP1	4.4817	15.4802	-0.6402	23.2603
NCI-H2141	CTRP1	4.4848	5.1406	4.4083	8.7826
UMC-11	GDSC1	4.4868	8.1495	2.3157	11.4941
HCC4006	CTRP1	4.4869	14.529	-0.1609	35.1614
HCC1359	CTRP1	4.4876	4.9152	4.468	8.3045
NCI-H1623	CTRP2	4.5027	10.4195	1.8931	14.2472
NCI-H345	GDSC1	4.5045	6.3003	3.2384	4.4067
HCC44	CTRP2; CTRP1	4.51	6.0392	4.06	5.3885
LK2	CTRP2	4.5196	5.1618	4.4358	3.7956
NCI-H1781	CTRP1	4.5246	14.2278	0.022	34.5345
NCI-H1581	CTRP2	4.5248	6.9137	3.6479	6.9562
HOP-62	CTRP2	4.5274	5.8261	4.1689	4.817
NCI-H1876	CTRP1	4.5356	10.4245	1.9284	27.187
NCI-H1573	GDSC1	4.5408	8.7183	2.075	13.0682
HCC33	CTRP1	4.5521	6.5791	3.8439	13.2334
HCC1588	CTRP2	4.5642	5.9188	4.1627	4.7504
HCC1438	CTRP2	4.5662	5.0196	4.5291	3.3152
NCI-H1373	CTRP2; CTRP1	4.5664	6.6959	3.8008	6.3162
RERF-LC-KJ	CTRP1	4.568	9.651	2.3419	24.673
HCC2279	CTRP2	4.5698	16.6493	-1.1581	24.4871
BEN	CTRP2; CTRP1	4.5738	5.8876	4.1937	4.6913
NCI-H1755	CTRP2; CTRP1	4.5776	7.2955	3.5179	7.4633
NCI-H727	CTRP2; CTRP1	4.5802	8.4288	2.9601	9.7791
NCI-H2170	CTRP2	4.5823	5.9646	4.1591	4.7212
NCI-H1437	CTRP1	4.5855	5.6589	4.3096	9.0078
HCC2935	CTRP1	4.586	12.2371	1.0685	30.8718
A-549	CTRP2; CTRP1	4.5881	8.3589	3.0018	9.5887
DMS 114	CTRP2	4.5942	13.2004	0.5854	19.0037
DMS 79	CTRP2	4.5988	5.7763	4.2631	4.2591
COR-L105	CTRP2	4.5993	8.2911	3.0366	9.3377
NCI-H1915	CTRP2; CTRP1	4.5998	6.3859	3.9825	5.4909
HCC4006	CTRP2; CTRP1	4.6012	7.3086	3.533	7.3481
NCI-H2023	CTRP2; CTRP1	4.6094	6.5922	3.8916	5.8432
NCI-H2228	CTRP2	4.6156	14.208	0.1005	20.6106
NCI-H522	CTRP2; CTRP1	4.6301	5.9519	4.2189	4.4516
MOR/CPR	CTRP2	4.6306	5.0558	4.5896	2.9007
IA-LM	CTRP2	4.6426	6.4886	3.9651	5.3769
NCI-H2106	CTRP2	4.6451	5.9662	4.2195	4.3234
T3M-10	CTRP1	4.6472	6.9338	3.7596	13.5079
DV-90	CTRP1	4.6477	5.31	4.5232	6.8544
NCI-H841	CTRP1	4.6763	10.8175	1.8549	26.926
COLO 699	CTRP2; CTRP1	4.6784	9.2546	2.636	10.9203
HCC1359	CTRP1	4.6837	5.3091	4.5617	6.324
IST-SL1	GDSC1	4.6842	11.5681	0.7699	20.7265
HCC15	CTRP2; CTRP1	4.718	13.8737	0.3643	19.5756
NCI-H526	CTRP2	4.7208	14.5809	0.0039	20.7078
NCI-H1184	CTRP2	4.7259	5.888	4.3347	3.6606
HCC827	CTRP2; CTRP1	4.7345	9.6961	2.4647	11.5133
NCI-H661	CTRP2; CTRP1	4.7397	7.5165	3.5549	6.9593
HCC95	CTRP2	4.7428	8.6631	2.9779	9.2832
NCI-H2073	CTRP1	4.7519	6.5982	4.0205	10.7084
NCI-H2405	CTRP2; CTRP1	4.7697	7.996	3.3429	7.7833
NCI-H647	CTRP2	4.7722	6.2585	4.1978	4.121
LB647-SCLC	GDSC1	4.7971	7.8572	2.6886	7.7566
NCI-H1734	CTRP2	4.8071	7.0328	3.8461	5.5142
Sq-1	CTRP2; CTRP1	4.8075	6.5493	4.095	4.5601
NCI-H1155	CTRP2	4.8087	6.1315	4.2937	3.6418
HCC33	GDSC1	4.8146	13.6066	-0.1424	24.595
NCI-H1651	CTRP2	4.815	6.8953	3.9215	5.1822
NCI-H2030	CTRP2; CTRP1	4.8259	6.6491	4.0622	4.6574
NCI-H3255	CTRP1	4.8437	6.736	4.0349	10.1555
NCI-H69	GDSC1	4.8626	9.0325	2.1615	11.4378
NCI-H1650	GDSC1	4.8728	43.8347	-15.1948	43.2013
DMS 79	GDSC1	4.8774	10.3355	1.5304	15.6619
NCI-H2126	CTRP2; CTRP1	4.8826	7.4388	3.7191	6.4016
T3M-10	CTRP2; CTRP1	4.8881	5.8175	4.5293	2.5765
BEN	CTRP2; CTRP1	4.8892	5.8029	4.5374	2.5406
NCI-H526	GDSC1	4.8919	15.6754	-1.112	27.9184
COR-L23	CTRP1	4.8932	6.1347	4.3773	6.8651
NCI-H2461	GDSC1	4.8976	27.1582	-6.8399	38.288
NCI-H2444	CTRP2	4.9003	6.4899	4.1983	3.8446
DMS 53	GDSC1	4.9027	11.3887	1.0283	18.5993
NCI-H513	GDSC1	4.9164	7.9767	2.7139	7.2364
CAL-12T	CTRP2; CTRP1	4.9325	9.3097	2.8273	9.6101
Calu-3	CTRP2; CTRP1	4.9433	7.1621	3.9095	5.0543
EPLC-272H	CTRP2; CTRP1	4.9515	7.9621	3.5168	6.6854
Calu-1	CTRP2	4.9523	9.614	2.6824	10.0953
NCI-H650	CTRP2; CTRP1	4.9565	7.0399	3.9818	4.7242
Lu-165	GDSC1	4.9565	8.0515	2.7053	7.1921
SBC-5	CTRP2	4.9601	5.6841	4.6518	1.8204
NCI-H1581	GDSC1	4.9735	10.5874	1.4782	15.6899
NCI-H1436	GDSC1	4.9766	9.6791	1.9275	12.7293
SW1271	CTRP2	4.9767	6.4353	4.2917	3.2968
NCI-H1781	CTRP1	4.9823	9.0846	2.9818	18.3947
NCI-H1838	CTRP2	4.9863	7.5926	3.7215	5.6738
NCI-H2081	GDSC1	4.9999	8.8878	2.331	9.8165
NCI-H2172	CTRP2; CTRP1	5.0102	7.1176	3.9887	4.589
NCI-H3255	CTRP1	5.0186	6.0687	4.52	5.0267
HCC1833	CTRP2; CTRP1	5.026	10.5535	2.2841	11.6724
CAL-12T	CTRP2; CTRP1	5.0542	6.9566	4.1061	4.0101
NCI-H1650	CTRP2	5.0726	7.4251	3.8774	4.851
LUDLU-1	CTRP2	5.0733	6.7775	4.2018	3.4861
NCI-H1755	CTRP2; CTRP1	5.0788	16.9291	-0.8596	23.8402
RERF-LC-MS	GDSC1	5.0806	17.4306	-1.8374	29.5321
HARA [Human squamous cell lung carcinoma]	CTRP2; CTRP1	5.0842	13.3906	0.9141	16.891
NCI-H748	GDSC1	5.094	7.224	3.1827	3.3951
NCI-H2286	CTRP2; CTRP1	5.1077	30.2188	-7.4804	34.5359
NCI-H2085	CTRP2	5.111	6.962	4.1405	3.6729
COR-L23	CTRP1	5.1171	6.6892	4.2917	6.6773
HCC827	GDSC1	5.1179	19.4052	-2.7919	31.7725
NCI-H2444	CTRP2	5.124	6.3492	4.4571	2.319
NCI-H1793	GDSC1	5.1347	16.9007	-1.5309	28.5096
MOR/CPR	CTRP2	5.1622	5.9516	4.6848	1.2988
NCI-H1869	CTRP2	5.1908	9.8957	2.7397	9.3967
NCI-H292	CTRP2	5.196	7.918	3.7319	5.2312
NCI-H2172	CTRP2; CTRP1	5.2006	6.6596	4.3733	2.6169
NCI-H2291	CTRP2	5.2079	8.6422	3.3799	6.6867
HCC95	CTRP2	5.2163	6.5593	4.425	2.2902
NCI-H2126	CTRP2; CTRP1	5.225	5.9475	4.7442	1.0335
NCI-H510A	GDSC1	5.2583	15.3478	-0.6624	25.2832
NCI-H727	CTRP2; CTRP1	5.2729	7.0228	4.2491	3.0095
Lu-65	CTRP2; CTRP1	5.2734	7.6362	3.9444	4.2826
NCI-H524	GDSC1	5.3071	11.584	1.2345	16.161
NCI-H1694	GDSC1	5.311	10.0307	1.995	11.2987
HCC1195	CTRP2; CTRP1	5.3482	6.729	4.451	2.0461
NCI-H2818	GDSC1	5.3631	13.2277	0.4671	20.1423
LOU-NH91	CTRP2	5.3638	7.3589	4.1413	3.2222
HCC366	CTRP2	5.3803	7.556	4.0564	3.5481
NCI-H2141	GDSC1	5.3843	10.8395	1.654	13.35
NCI-H2029	GDSC1	5.3977	8.8982	2.5947	6.8711
HCC15	CTRP2; CTRP1	5.4062	8.7813	3.4787	5.9951
RERF-LC-A1	CTRP2	5.4285	9.08	3.3371	6.4673
NCI-H358	CTRP2; CTRP1	5.4389	7.2989	4.2377	2.7811
RERF-LC-Ad1	CTRP2	5.4584	6.5421	4.6061	1.1797
NCI-H460	CTRP2; CTRP1	5.4669	11.6433	2.1002	11.5824
Lu-65	GDSC1	5.4719	15.8643	-0.7546	25.008
NCI-H2373	GDSC1	5.4779	13.1943	0.5688	19.2973
KNS-62	CTRP2; CTRP1	5.484	12.275	1.7987	12.7543
NCI-H2228	CTRP2	5.4975	7.7302	4.0578	3.3502
NCI-H2009	CTRP2; CTRP1	5.4977	7.4445	4.2091	2.806
A-549	CTRP2; CTRP1	5.5131	7.4688	4.2083	2.7852
NCI-H1339	CTRP2	5.5267	16.4277	-0.2505	19.9185
LCLC-97TM1	CTRP2; CTRP1	5.5683	9.8847	3.0563	7.4723
HCC78	CTRP2; CTRP1	5.5792	7.8123	4.088	3.1763
HARA [Human squamous cell lung carcinoma]	CTRP2; CTRP1	5.6035	8.0952	3.9672	3.635
NCI-H1836	GDSC1	5.6075	13.8999	0.3175	20.1526
NCI-H720	GDSC1	5.6096	6.9558	3.5536	0.5344
NCI-H446	GDSC1	5.6137	10.3513	2.0476	10.1304
HCC78	CTRP2; CTRP1	5.6487	7.1847	4.4382	1.6646
NCI-H1304	GDSC1	5.6692	7.7111	3.2818	1.7832
NCI-H1395	CTRP2	5.6693	11.5123	2.3153	10.2709
NCI-H226	CTRP2	5.6777	7.8995	4.1039	2.8851
PC-14	CTRP2	5.697	13.3126	1.4408	13.6834
HCC2108	CTRP2; CTRP1	5.7012	8.1474	4.0117	3.3027
HCC827	CTRP2; CTRP1	5.7037	7.9951	4.0872	2.992
NCI-H292	CTRP2	5.7128	14.5541	0.8344	15.9084
NCI-H441	CTRP2; CTRP1	5.7271	9.0148	3.6064	4.9252
HCC2279	CTRP2	5.7281	9.2147	3.498	5.2931
NCI-H2342	CTRP2; CTRP1	5.7321	12.437	1.9148	11.8427
NCI-H1838	GDSC1	5.7344	7.8745	3.2461	1.8957
NCI-H2110	CTRP2; CTRP1	5.751	12.097	2.0987	11.0755
NCI-H2227	GDSC1	5.7561	7.4011	3.446	0.856
NCI-H196	GDSC1	5.7675	12.7094	1.0159	16.0982
NCI-H226	CTRP2	5.777	10.5039	2.8985	7.6915
SK-LU-1	CTRP2; CTRP1	5.8094	14.5426	0.927	16.4144
NCI-H187	GDSC1	5.8466	9.3849	2.6464	5.5085
NCI-H1155	GDSC1	5.8495	7.2227	3.5508	0.3948
SW1573	GDSC1	5.873	14.5588	0.1885	20.0112
NCI-H23	GDSC1	5.8758	7.7106	3.3781	1.0496
RERF-LC-KJ	CTRP1	5.8844	9.5352	3.4659	11.0673
HCC1171	CTRP2	5.9309	9.4228	3.5428	4.7919
SK-LU-1	CTRP2; CTRP1	5.9636	10.1362	3.229	6.1029
NCI-H838	GDSC1	5.9725	23.5594	-4.1884	32.4831
Lu-134-A	GDSC1	5.9818	10.733	2.107	8.827
LCLC-103H	CTRP2; CTRP1	6.0214	8.2886	4.1583	2.2787
HCC366	CTRP2	6.0417	16.4405	0.1546	17.6544
NCI-H1650	CTRP2	6.0422	15.0646	0.8396	19.6438
NCI-H1993	GDSC1	6.0573	21.7196	-3.2092	30.3797
SBC-5	CTRP2	6.105	7.1525	4.6888	0.3261
PC-14	CTRP2	6.1409	8.5843	4.0834	2.349
NCI-H1792	CTRP2; CTRP1	6.1664	9.5039	3.6778	3.9791
NCI-H2291	GDSC1	6.1818	8.6907	3.127	1.9676
SW1573	CTRP2	6.2422	19.1567	-1.0401	25.538
NCI-H441	CTRP2; CTRP1	6.2447	18.1403	-0.5218	19.4854
NCI-H1793	CTRP2; CTRP1	6.2515	14.4559	1.3135	13.2523
HCC1588	CTRP2	6.2892	18.5258	-0.6891	19.8508
RERF-LC-Ad1	CTRP2	6.3105	7.3451	4.7023	0.2062
NCI-H1876	GDSC1	6.3136	8.469	3.2747	1.1076
NCI-H196	CTRP2	6.3469	9.6645	3.7087	3.5415
NCI-H2110	CTRP1	6.3579	21.6434	-2.1772	33.712
SW1573	CTRP2	6.5144	19.8953	-1.1944	20.897
NCI-H1666	GDSC1	6.5335	8.6824	3.2861	0.8838
COR-L95	GDSC1	6.5676	13.6313	1.1193	13.4557
RERF-LC-MS	CTRP2	6.6893	15.5314	1.1007	13.2357
RERF-LC-A1	CTRP2	6.7467	13.6469	2.066	9.4889
NCI-H1792	CTRP2; CTRP1	6.7651	16.2419	0.8178	14.1906
LOU-NH91	CTRP2	6.7998	19.463	-0.7593	23.4927
LC-1/sq-SF	CTRP2; CTRP1	6.865	14.9986	1.502	11.5335
NCI-H1092	GDSC1	6.8657	22.7309	-3.0977	28.3169
NCI-H322M	GDSC1	7.0141	9.0838	3.3281	0.4704
NCI-H322	CTRP2	7.058	19.3601	-0.5124	18.0053
NCI-H838	CTRP2	7.1259	13.8851	2.2154	8.3441
NCI-H2009	CTRP2; CTRP1	7.1772	18.5037	0.0099	16.2393
HCC1195	CTRP2; CTRP1	7.3448	15.0246	1.8285	12.5779
HOP-92	CTRP2	7.4521	20.33	-0.6964	17.9129
VMRC-LCD	CTRP2; CTRP1	7.4959	23.7798	-2.3563	22.2773
NCI-H460	CTRP2; CTRP1	7.6821	14.6286	2.2438	7.5378
RERF-LC-Ad2	CTRP2	7.7139	13.446	2.805	5.3169
NCI-H2073	CTRP1	7.9435	16.3744	1.5869	17.1566
RERF-LC-Sq1	GDSC1	8.4218	20.555	-0.946	18.6793
HCC1171	CTRP2	8.5609	21.7225	-0.5769	15.8718
NCI-H2030	CTRP2; CTRP1	9.9783	20.9286	0.7529	9.9057
HCC2108	CTRP2; CTRP1	10.3425	28.4664	-2.5878	18.7475
NCI-H196	CTRP2	10.4163	24.484	-0.646	13.5878
Hs 888.Lu	CTRP2	6.2365	14.3883	1.3249	13.1676

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
CBTCi002-A	GDSC1	2.4675	8.0398	0.5944	30.5942

Cancer Drug Sensitivity Data Curated from 108 Cell Line(s) in Ovary Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
2004	CTRP2	2.4158	12.0444	-0.8309	28.6045
A2780	GDSC1	-2.6391	4.9777	-3.5342	66.5842
IGROV-1	GDSC1	-1.7907	5.3409	-2.7307	62.0627
TOV-112D	GDSC1	-1.714	2.749	-1.9443	65.7695
A2780	CTRP2; CTRP1	-1.6991	7.342	-3.0453	46.3772
EFO-27	GDSC1	-0.5186	10.5647	-3.5297	52.4415
OAW42	GDSC1	-0.2705	6.7439	-1.6175	51.8781
SK-OV-3	GDSC1	-0.1061	5.9686	-1.1389	50.8207
OVKATE	CTRP1	0.2838	12.1459	-2.9664	55.6822
OVTOKO	GDSC1	0.9683	8.8178	-1.241	43.8808
OVCAR-4	GDSC1	1.0217	5.865	0.1018	40.8856
OVK18	CTRP2; CTRP1	1.6967	11.065	-1.0601	32.9671
COV434	CTRP1	1.8209	7.4829	0.6597	47.7897
EFO-21	GDSC1	1.9474	8.9238	-0.3284	36.7045
Kuramochi	GDSC1	2.1231	5.0295	1.601	26.8839
OC 314	GDSC1	2.1887	8.463	0.1241	33.9589
FU-OV-1	GDSC1	2.3053	4.4373	2.015	23.1154
COV434	CTRP2; CTRP1	2.3776	9.8475	0.1796	25.7309
OVCAR-8	GDSC1	2.3951	5.7611	1.5809	25.5262
A2780	CTRP2; CTRP1	2.5301	6.0186	1.9883	18.7828
RMUG-S	CTRP1	3.2883	7.9184	1.977	33.678
OVISE	GDSC1	3.3556	9.4794	0.7063	26.0047
TYK-nu	GDSC1	3.3653	4.3892	3.1725	9.2623
OVCAR-5	GDSC1	3.4982	5.1295	2.9771	10.0892
JHOS-4	CTRP1	3.6368	6.0275	3.1661	23.9446
OC 314	CTRP2	3.804	6.585	3.0952	10.951
OV7	CTRP2; CTRP1	3.8202	7.1071	2.8808	11.8525
TOV-112D	CTRP2	3.8815	8.8807	2.0879	14.8355
OVKATE	CTRP1	3.9038	11.2898	0.9352	34.4676
OAW28	CTRP2	3.9887	8.6083	2.321	14.606
OVK18	CTRP2; CTRP1	4.0158	7.0943	3.0801	10.5664
RMG-I	GDSC1	4.0933	6.5491	2.8023	9.1035
OVKATE	GDSC1	4.1193	5.3404	3.4264	4.1096
OVCAR-5	CTRP2	4.1929	8.4464	2.5904	12.0767
Caov-3	CTRP2; CTRP1	4.2188	13.3494	0.1943	22.4684
RMG-I	CTRP2; CTRP1	4.3586	10.6149	1.6777	16.5347
OV-90	GDSC1	4.3753	9.5236	1.5443	17.2404
EFO-21	CTRP1	4.3912	6.7397	3.6131	16.0445
HEY A8	CTRP2; CTRP1	4.4029	11.8426	1.106	18.7249
OAW28	GDSC1	4.4149	9.9616	1.3575	18.2799
SNU-119	CTRP2	4.4241	6.2575	3.8664	6.2948
OAW42	CTRP2; CTRP1	4.4328	8.3645	2.8591	10.5162
OVCAR-3	GDSC1	4.4362	13.7669	-0.5249	27.3147
IGROV-1	CTRP2; CTRP1	4.4793	7.0253	3.5589	7.5135
JHOS-4	CTRP1	4.4956	5.9523	4.0859	11.4171
RMUG-S	CTRP1	4.5198	6.0536	4.063	11.4874
JHOM-1	CTRP1	4.5666	8.0846	3.1184	19.2506
ES2	CTRP2	4.6219	11.2019	1.6069	15.1335
OVMANA	CTRP1	4.6474	5.8514	4.2831	8.9045
OV56	CTRP2	4.6621	5.1669	4.5883	2.8123
TYK-nu	CTRP2; CTRP1	4.6826	6.3487	4.0787	4.9043
DOV13	CTRP2	4.7085	8.9762	2.792	10.1295
HEY A8	CTRP2; CTRP1	4.7108	7.315	3.629	6.7112
OV7	CTRP1	4.7129	5.4503	4.5321	6.4056
COV318	CTRP1	4.7247	6.2399	4.1711	9.5002
RMG-I	CTRP2; CTRP1	4.7459	7.0474	3.7931	5.9511
OVCAR-8	CTRP2; CTRP1	4.7894	11.3157	1.7032	14.4827
TOV-21G	CTRP2	4.7968	6.6376	4.0331	4.7543
Caov-3	GDSC1	4.814	8.0991	2.5828	8.4998
ONCO-DG-1	CTRP2	4.8601	8.4225	3.1995	8.1169
MCAS	CTRP2	4.864	8.4984	3.1649	8.254
IGROV-1	CTRP2; CTRP1	4.8944	6.5993	4.1476	4.1563
FU-OV-1	CTRP2	4.9252	8.4048	3.2638	10.5067
TYK-nu	CTRP2; CTRP1	4.9351	11.8943	1.5375	15.8204
OAW42	CTRP1	4.9481	6.3018	4.3429	6.9272
Kuramochi	CTRP2	4.962	11.3213	1.837	13.5312
SNU-119	CTRP2	5.0034	6.2066	4.4288	2.6675
ES2	CTRP2	5.0408	5.8343	4.6465	1.6794
OAW28	CTRP2	5.0931	6.655	4.2793	3.1234
COV362	CTRP2; CTRP1	5.0992	8.4706	3.3865	6.9448
OVCAR-4	CTRP2; CTRP1	5.1048	13.3804	0.9364	16.7689
OVSAHO	CTRP2	5.1204	7.9224	3.6682	5.6393
ONCO-DG-1	CTRP2	5.1262	6.2266	4.52	2.0513
ES-2	GDSC1	5.142	6.9676	3.3251	2.342
OVCAR-4	CTRP2; CTRP1	5.1906	7.7481	3.8224	4.9437
COV644	CTRP1	5.2335	11.9606	1.7524	25.0781
DOV13	CTRP2	5.2718	6.4859	4.5032	1.8718
JHOC-5	CTRP2; CTRP1	5.277	12.6176	1.4597	14.468
EFO-21	CTRP2; CTRP1	5.3054	8.6891	3.4449	6.3166
FU-OV-1	CTRP2	5.3064	6.8285	4.3602	2.4082
OVMANA	CTRP1	5.4128	6.9886	4.3707	4.8816
OVISE	CTRP2	5.4211	7.8719	3.931	4.0016
SNU-840	CTRP2; CTRP1	5.4442	12.3797	1.7144	14.0358
OVTOKO	CTRP2	5.4445	10.4266	2.6791	9.1796
Caov-3	CTRP2; CTRP1	5.4705	7.8049	4.012	3.6633
Kuramochi	CTRP2	5.4939	9.9509	2.9549	7.9461
COV318	CTRP1	5.5497	7.1951	4.367	4.4727
MCAS	CTRP2	5.5963	11.3195	2.3541	10.2429
OV-90	CTRP1	5.623	17.9658	-0.9307	33.1409
COV362	CTRP1	5.6432	13.3817	1.3738	25.3484
OVCAR-8	CTRP2; CTRP1	5.761	10.3253	2.9855	7.4361
JHOC-5	CTRP2; CTRP1	5.8048	8.758	3.788	4.0587
TOV-21G	GDSC1	6.0065	7.4763	3.5199	0.4065
OVISE	CTRP2	6.014	7.1926	4.6303	0.5429
SNU-840	CTRP2; CTRP1	6.0301	8.9619	3.8454	3.4991
OVTOKO	CTRP2	6.0324	14.1028	1.31	13.5787
SNU-8	CTRP2	6.0899	15.6144	0.6034	16.0416
SK-OV-3	CTRP2; CTRP1	6.1031	8.2476	4.2278	1.9161
SNU-8	CTRP2	6.1156	10.8391	2.9841	6.7907
Caov-4	GDSC1	6.2292	17.7595	-1.1219	24.2721
SK-OV-3	CTRP2; CTRP1	6.4473	13.3971	1.9827	11.0495
EFO-27	CTRP2; CTRP1	6.5301	11.8744	2.7857	7.036
COV644	CTRP2; CTRP1	6.681	10.7127	3.4425	4.2217
JHOM-1	CTRP2; CTRP1	6.7935	14.272	1.8058	10.493
OVSAHO	CTRP2	6.9145	17.6514	0.2235	15.9154
JHOS-2	CTRP2	6.9412	10.839	3.5337	3.487
EFO-27	CTRP1	7.3953	16.5318	1.1337	20.8209
OV-90	CTRP2; CTRP1	8.7768	17.0377	1.8115	7.7436

Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Soft Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Aska-SS	CTRP2	2.7857	21.8006	-5.2832	36.082
Yamato-SS	CTRP2	5.3545	18.2519	-1.3027	23.3118
SK-LMS-1	GDSC1	-2.1691	2.5545	-2.4001	69.0469
MFH-ino	GDSC1	-1.7346	2.5043	-1.9226	66.3919
Hs 633.T	GDSC1	-1.4707	2.0606	-1.5741	65.2564
G-401	GDSC1	-1.0006	3.4073	-1.3077	59.4268
G-402	GDSC1	0.619	5.1799	-0.068	44.248
SW872	GDSC1	0.7939	4.639	0.3079	41.9545
VA-ES-BJ	GDSC1	1.3089	15.2831	-4.0159	45.0341
Rh41	CTRP2	1.3655	10.9157	-1.327	32.7848
EW-8	GDSC1	1.5377	6.9197	0.1924	37.2903
A-204	GDSC1	1.6992	8.3653	-0.3064	37.9367
SK-UT-1	GDSC1	1.7043	4.5952	1.3101	31.1304
MES-SA	GDSC1	1.7706	9.1279	-0.5965	38.3505
HT-1080	GDSC1	2.2004	3.2711	2.1767	22.6454
G-401	CTRP1	2.2856	7.026	1.3358	43.0763
TTC-709	CTRP2	2.708	17.2403	-3.0955	32.9592
SW982	GDSC1	2.713	17.5591	-3.8798	40.3637
Rh30	GDSC1	2.9444	6.7202	1.6841	22.1103
A-204	CTRP2	3.0382	10.6357	0.4407	23.0764
RKN	GDSC1	3.1875	13.5496	-1.4678	34.5409
Rh41	GDSC1	3.2095	8.1063	1.2558	23.6109
TE 441.T	CTRP2	3.2111	9.3064	1.2431	19.7493
GCT	GDSC1	3.2953	9.5509	0.6174	26.7003
TE 617.T	CTRP2	3.3741	9.1769	1.4622	18.5124
Rh41	CTRP2	3.411	5.9375	2.9577	12.5398
Rh18	CTRP2	3.4689	5.8758	3.0434	12.0505
RD	GDSC1	3.5104	10.8527	0.1576	27.9292
G-402	CTRP2	3.6433	8.5633	2.0144	15.6918
STS-0421	GDSC1	3.6655	15.5695	-2.0658	34.335
GCT	CTRP2	3.7494	8.167	2.3059	14.2662
SW684	GDSC1	4.1543	5.2664	3.4904	3.4938
SK-LMS-1	CTRP2	4.3513	11.7215	1.112	17.6068
KYM-1	CTRP2	4.3534	8.0544	2.9309	10.3118
MES-SA	CTRP2	4.4299	5.4358	4.2375	4.8018
G-401	CTRP2; CTRP1	4.765	9.3843	2.6467	10.6982
TE 441.T	GDSC1	5.089	8.9856	2.3461	9.4567
Rh18	CTRP2	5.1442	11.7546	1.7721	13.4314
RKN	CTRP2; CTRP1	5.3196	9.6171	2.9932	8.7587
RKN	CTRP2; CTRP1	5.5688	8.098	3.9405	3.7997
HT-1080	CTRP1	5.6043	14.8496	0.6103	28.6423
BT-16	CTRP2	5.7714	9.3533	3.4617	5.3733
KYM-1	GDSC1	6.1297	13.3542	0.9568	15.4516
Hs 729.T	CTRP2	6.1721	12.2406	2.3374	9.9661
SW982	CTRP2	6.2733	11.9902	2.5348	8.3666
BT-12	CTRP2	6.5714	12.3823	2.557	7.8165
SK-UT-1	CTRP2	6.9708	10.9705	3.4913	3.612
HT-1080	CTRP2; CTRP1	7.0122	15.9049	1.1651	12.545
RD	CTRP2	7.191	11.7853	3.2506	4.2612
Tm87-16	CTRP2	7.5644	20.374	-0.6351	17.5532

Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SYO-1	CTRP2	4.2795	15.2385	-0.7033	23.8202
P-STS	CTRP2	6.5599	16.449	0.5506	15.4054

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
U-CH1	CTRP2	6.7368	10.352	3.6333	3.3499

Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Pleura Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MSTO-211H	CTRP2; CTRP1	-1.4219	5.6179	-2.174	56.0931
MSTO-211H	CTRP2; CTRP1	1.7642	5.91	1.1995	23.9229
IST-Mes1	GDSC1	3.0368	6.8776	1.6966	21.5974
MPP 89	GDSC1	3.3777	6.0898	2.4	15.0304
NCI-H2052	GDSC1	3.5959	4.9789	3.1433	8.3777
NCI-H28	CTRP2; CTRP1	3.9305	9.722	1.7311	16.2242
NCI-H28	GDSC1	4.4019	21.1719	-4.2534	36.2571
MPP 89	CTRP2	4.7225	6.2332	4.1642	4.3716
IST-Mes1	CTRP2	5.0705	9.5694	2.8036	9.3597
NCI-H28	CTRP2; CTRP1	5.1892	7.9092	3.7408	5.2889
MSTO-211H	GDSC1	5.2554	7.4675	3.167	3.1779
NCI-H2052	CTRP2; CTRP1	5.2736	7.8942	3.8159	4.8199
NCI-H2052	CTRP2; CTRP1	5.3388	14.3253	0.6568	22.199
ACC-MESO-1	CTRP2	5.5406	7.1422	4.3747	1.9892
NCI-H2452	CTRP2	5.7417	9.593	3.3218	5.9996
NCI-H2452	CTRP2	5.7466	19.3933	-1.5536	23.2358
ACC-MESO-1	CTRP2	5.7818	11.0374	2.6381	8.7558
NCI-H2452	GDSC1	5.8649	15.8796	-0.4663	22.8265
JL-1	CTRP2	7.0181	15.0437	1.5789	10.9387

Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Prostate Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
22Rv1	GDSC1	1.7184	7.9623	-0.0996	37.213
VCaP	GDSC1	1.7328	10.2117	-1.1512	39.814
NCI-H660	CTRP2	1.9155	9.2037	0.0053	27.5055
LNCaP clone FGC	CTRP2	2.1569	7.6487	0.9359	23.6663
22Rv1	CTRP2	2.264	15.4645	-2.6319	33.1539
DU145	GDSC1	2.845	5.572	2.1234	19.5316
PC-3	GDSC1	3.3923	7.2062	1.866	18.8635
LNCaP clone FGC	GDSC1	3.4194	7.6482	1.672	20.0728
PaCa-3	CTRP2; CTRP1	4.2323	5.4001	4.0451	6.1792
VCaP	CTRP2	4.899	15.5119	-0.311	21.3433
22Rv1	CTRP2	4.9591	8.7294	3.1303	8.2097
DU145	CTRP2	5.0994	8.9044	3.16	7.8131
PaCa-3	CTRP1	5.1627	11.3226	2.0131	23.9663

Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Salivary Gland Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
A-253	GDSC1	3.0012	6.192	1.9907	19.7321
A-253	CTRP2	3.9477	7.057	3.0235	10.8782
YD-15	CTRP2	5.5424	7.7777	4.0672	3.2403
YD-15	CTRP2	7.537	20.5893	-0.7612	17.9671

Cancer Drug Sensitivity Data Curated from 121 Cell Line(s) in Skin Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Mel JuSo	GDSC1	-5.9977	4.4562	-7.0387	76.823
HMV-II	GDSC1	-1.4099	7.0819	-2.9597	58.3134
WM793	GDSC1	-1.0851	18.1281	-7.6478	53.0457
A-431	GDSC1	-0.9223	5.5369	-1.8581	56.7861
SK-MEL-2	GDSC1	-0.9181	2.7996	-1.0937	59.4303
A-388	GDSC1	-0.721	8.0909	-2.6465	54.1465
MZ-MEL-7	GDSC1	-0.548	5.41	-1.4091	54.2905
WM278	GDSC1	-0.2056	4.9377	-0.8761	51.7812
A101D	GDSC1	-0.0438	8.7372	-2.2276	50.2532
SK-MEL-24	GDSC1	0.1294	7.0777	-1.3333	49.0951
CHL-1	GDSC1	0.2835	7.7379	-1.4538	48.124
451Lu	GDSC1	0.2968	6.8138	-1.0484	47.8208
G-361	GDSC1	0.3403	4.4715	-0.132	46.6558
SH-4	GDSC1	0.4545	5.8186	-0.4828	46.1732
WM1552C	GDSC1	0.4763	6.6524	-0.7934	46.3643
A-375	GDSC1	0.7761	7.1422	-0.6877	44.2195
HT-144	GDSC1	0.8006	4.3168	0.417	41.5612
IGR-37	GDSC1	0.8202	5.7474	-0.0656	42.7365
MZ-MEL-2	GDSC1	0.8304	5.6924	-0.0334	42.5881
IGR-1	GDSC1	0.8765	5.1991	0.2022	41.6374
IPC-298	GDSC1	0.9137	6.0751	-0.0968	42.1502
COLO 679	GDSC1	0.918	5.0643	0.2957	41.0536
Mel Ho	GDSC1	1.1364	4.6034	0.6915	38.0245
IST-MEL1	GDSC1	1.1792	7.2176	-0.3058	40.9222
MeWo	GDSC1	1.186	7.4778	-0.4142	41.1357
LB2518-MEL	GDSC1	1.4719	4.2349	1.1735	33.3754
WM35	GDSC1	1.6317	5.0973	1.0504	33.0224
Hs 940.T	GDSC1	1.6454	4.4824	1.2841	31.6452
SK-MEL-30	GDSC1	1.7061	7.0111	0.3228	35.8267
SK-MEL-3	GDSC1	1.7819	8.7675	-0.4146	37.8043
GAK	GDSC1	1.8359	4.2563	1.5635	28.7899
G-mel	GDSC1	1.8471	38.6487	-15.1496	47.2588
M14	GDSC1	1.854	3.0825	1.8304	26.9734
COLO 792	CTRP2	2.0838	5.6264	1.6376	21.3066
A2058	GDSC1	2.2276	3.948	2.0797	23.119
LB373-MEL-D	GDSC1	2.285	7.7568	0.5533	31.7051
Mel JuSo	CTRP2	2.3997	12.7503	-1.1861	29.589
WM88	CTRP2	2.5609	6.7727	1.724	19.6164
CP66-MEL	GDSC1	2.6841	4.2687	2.4825	17.7955
G-361	CTRP2; CTRP1	2.7255	6.1127	2.1632	18.8186
Hs 938.T	GDSC1	2.9776	4.5032	2.7155	14.5714
SK-MEL-24	CTRP2	3.0563	7.5713	1.8946	17.6302
RPMI-7951	GDSC1	3.1665	15.4979	-2.4576	36.7722
DJM-1	GDSC1	3.1872	4.2183	3.045	11.1155
COLO 792	GDSC1	3.2344	11.4299	-0.3708	31.0847
RVH-421	CTRP2	3.3558	8.008	1.9958	16.4693
IPC-298	CTRP2	3.3729	7.577	2.2114	16.6737
MMAc-SF	GDSC1	3.4257	10.6967	0.1618	28.2481
SK-MEL-28	GDSC1	3.4622	3.7244	3.4595	6.7394
RVH-421	GDSC1	3.6086	13.5601	-1.11	32.0649
COLO 829	GDSC1	3.6134	5.2688	3.0204	9.2499
SK-MEL-5	GDSC1	3.6479	6.8736	2.2602	14.9519
Hs 944.T	CTRP2; CTRP1	3.7543	5.5761	3.4667	13.25
HT-144	CTRP2	3.8329	10.5176	1.2425	18.2678
WM983B	CTRP2	4.0227	7.8644	2.7131	11.9637
Hs 936.T	CTRP2; CTRP1	4.1246	10.8585	1.3479	18.4275
LOX-IMVI	CTRP2	4.1848	9.2299	2.1982	14.6598
UACC-257	GDSC1	4.1904	9.2273	1.5433	17.903
CP50-MEL-B	GDSC1	4.2074	10.283	1.0297	20.9533
WM115	GDSC1	4.2106	9.272	1.5374	17.8686
Hs 852.T	CTRP2; CTRP1	4.2144	8.1029	2.7863	12.106
G-361	CTRP2; CTRP1	4.2649	5.456	4.0589	6.0347
MDA-MB-435S	CTRP2	4.333	10.9959	1.4568	17.4224
COLO 741	CTRP2; CTRP1	4.3466	21.3269	-3.676	30.5799
Hs 936.T	CTRP2; CTRP1	4.381	7.8183	3.0803	9.7143
Hs 940.T	CTRP2	4.4765	6.2566	3.9181	5.958
IGR-37	CTRP2	4.5661	5.4139	4.3899	3.8399
RPMI-7951	CTRP2	4.5747	7.7403	3.2875	8.3441
UACC-62	GDSC1	4.5968	13.0208	-0.0232	24.796
Mel Ho	CTRP2	4.5996	6.3174	4.0077	5.2997
Hs 852.T	CTRP2; CTRP1	4.6325	6.0455	4.177	4.617
Hs 944.T	CTRP2; CTRP1	4.6338	5.4257	4.4611	3.4722
A101D	CTRP2	4.6497	6.1366	4.1424	4.629
IGR-1	CTRP2	4.6704	7.5588	3.4634	7.4041
WM115	CTRP2	4.6828	10.1583	2.1802	13.5922
SK-MEL-28	CTRP2; CTRP1	4.7194	10.3699	2.1154	13.8709
A2058	CTRP2	4.758	5.2231	4.6698	2.2321
UACC-257	CTRP2	4.7791	7.642	3.5183	6.9456
SK-MEL-5	CTRP2; CTRP1	4.8283	7.2566	3.7624	5.906
Mel JuSo	CTRP2	4.8881	8.0087	3.43	7.0934
LOX-IMVI	CTRP2	4.9766	8.4189	3.3003	7.462
MDA-MB-435S	CTRP2	5.0074	5.8745	4.5981	1.9487
WM1799	CTRP2	5.0715	12.3051	1.4366	15.863
Mel Ho	CTRP2	5.1085	6.0182	4.6099	1.7065
WT2-iPS	GDSC1	5.1092	7.7201	2.9631	4.9181
IPC-298	CTRP2	5.1955	6.4613	4.4576	2.1896
SK-MEL-1	CTRP2; CTRP1	5.2083	9.461	2.981	8.4366
Hs 688(A).T	CTRP2	5.2486	21.3464	-2.937	27.3925
WM1799	CTRP2	5.3436	6.9395	4.3332	2.4591
WM793	CTRP2	5.3488	7.1736	4.2216	2.9134
A-375	CTRP2; CTRP1	5.3605	8.2318	3.7163	5.0826
IGR-39	CTRP2	5.3875	6.5946	4.5332	1.5697
A-375	CTRP2; CTRP1	5.3889	13.7968	0.9618	16.1225
SK-MEL-30	CTRP2	5.4094	11.4403	2.1453	12.2166
SK-MEL-28	CTRP2; CTRP1	5.4729	6.519	4.6382	1.1094
WT2-iPS	CTRP2	5.5271	13.4349	1.2443	14.7439
COLO 800	GDSC1	5.5394	10.9917	1.6891	12.691
LOX-IMVI	GDSC1	5.5829	11.2631	1.5881	13.2129
COLO 741	CTRP2; CTRP1	5.586	9.3971	3.3119	6.379
UACC-62	CTRP2	5.6	12.8099	1.6144	13.1908
COLO 783	GDSC1	5.7248	7.0555	3.5629	0.4266
VMRC-MELG	GDSC1	5.7285	9.4205	2.559	6.355
Hs 839.T	CTRP2	5.855	10.9406	2.7416	8.2068
Hs 294T	CTRP2	5.9014	13.3021	1.6061	12.6796
WM793	CTRP2	5.9118	14.47	1.0335	15.7434
Hs 895.T	CTRP2	5.9198	13.9933	1.2769	13.9028
SK-MEL-5	CTRP2; CTRP1	5.9743	11.8284	2.4035	10.1137
SK-MEL-1	GDSC1	5.9907	7.2981	3.5772	0.2576
WM266-4	CTRP2	6.0125	15.2457	0.7263	16.6966
SK-MEL-31	CTRP2	6.1407	7.8065	4.4345	1.0681
SK-MEL-1	CTRP2; CTRP1	6.3449	18.6011	-0.6726	19.7578
COLO 829	CTRP2	6.5349	15.9796	0.7638	14.7033
SK-MEL-30	CTRP2	6.5831	7.8987	4.6069	0.2942
SK-MEL-31	CTRP2	6.7265	13.1796	2.2791	9.2753
HMCB	CTRP2	7.1486	17.4756	0.4833	14.6627
MeWo	CTRP2	7.2222	15.3952	1.5525	10.7267
SK-MEL-3	CTRP2	7.3163	16.2151	1.2205	11.8064
CJM [Human melanoma]	CTRP2	8.3097	20.8693	-0.3396	15.5263
COLO 800	CTRP2	10.0967	26.7363	-1.9345	17.4509
K029AX	CTRP2	10.5368	23.3103	-0.0178	11.5973
EquiPSC Line K2	GDSC1	2.8441	8.1221	0.9111	27.2081

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HuTu 80	GDSC1	-1.7609	2.5399	-1.957	66.5017

Cancer Drug Sensitivity Data Curated from 83 Cell Line(s) in Stomach Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SNU-620	CTRP2	-6.2927	5.181	-7.3657	65.2997
ECC10	CTRP2	-1.023	4.0867	-1.3424	54.2253
IM95	GDSC1	-0.7397	5.5333	-1.6597	55.5718
AGS	GDSC1	-0.2808	14.9529	-5.354	50.9854
MKN28	GDSC1	-0.2342	7.3738	-1.8373	51.5249
HGC-27	GDSC1	0.3771	4.0019	0.0457	46.0583
RF-48	GDSC1	0.4559	14.059	-4.2203	48.2214
SNU-620	CTRP2	0.4638	5.3397	-0.0383	32.1495
NCC-StC-K140	CTRP2	0.4828	13.5673	-3.4318	39.2058
MKN1	GDSC1	0.5144	7.4884	-1.1075	46.4162
NCI-N87	CTRP2	0.632	9.8742	-1.6014	35.642
ECC10	GDSC1	1.1599	5.7661	0.2876	39.3706
MKN45	GDSC1	1.252	6.8564	-0.0728	39.8649
SNU-16	CTRP2	1.3873	4.9595	1.0762	25.4399
Fu97	GDSC1	1.5264	4.7581	1.0612	33.632
GSS	CTRP2	1.65	11.4213	-1.2793	31.8521
OCUM-1	GDSC1	1.7285	3.6653	1.6038	29.1839
NUGC-3	GDSC1	1.9241	8.2007	-0.0084	35.8036
HGC-27	CTRP2	1.9883	7.6821	0.7463	24.818
23132/87	GDSC1	2.4868	6.8512	1.1769	27.4975
TMK-1	GDSC1	2.6961	6.3987	1.5946	23.8964
GCIY	GDSC1	2.7018	6.8338	1.3956	25.1244
SNU-1	CTRP2	2.9984	9.8867	0.7612	22.0536
NCI-N87	GDSC1	3.1539	11.1861	-0.3204	31.2282
SNU-1	GDSC1	3.1711	19.3801	-4.3913	39.6572
SNU-5	CTRP2	3.2425	13.2157	-0.6255	25.9506
AGS	CTRP2; CTRP1	3.3579	5.2768	3.1388	12.096
Hs 746.T	CTRP2	3.509	7.9174	2.1893	15.319
ECC10	CTRP2	3.7242	5.4734	3.4673	9.7199
SNU-5	GDSC1	3.9711	5.2231	3.3642	5.1199
MKN7	CTRP1	4.0306	5.8853	3.6383	17.8032
Fu97	CTRP2; CTRP1	4.085	7.8846	2.7703	11.6658
NUGC-4	GDSC1	4.094	13.6867	-0.7652	29.3023
RERF-GC-1B	GDSC1	4.1715	7.3054	2.488	11.26
MKN74	CTRP2; CTRP1	4.2654	7.2264	3.2592	9.2405
SH-10-TC	CTRP1	4.3158	5.3435	4.1556	11.8561
GSS	CTRP2	4.3314	5.4312	4.1348	5.4689
23132/87	CTRP2	4.4014	9.3448	2.3373	12.6586
SNU-601	CTRP2	4.4098	5.6854	4.112	11.4822
KE-39	CTRP2	4.4274	8.9591	2.5518	11.7197
KATO III	CTRP2	4.6069	8.1396	3.1186	8.9795
MKN7	CTRP2; CTRP1	4.6334	5.5843	4.3917	3.7473
SNU-5	CTRP2	4.6407	7.7068	3.3634	7.8856
MKN74	CTRP2; CTRP1	4.7504	6.4979	4.0684	4.795
NCI-N87	CTRP2	4.8032	7.758	3.4817	7.0491
Fu97	CTRP2; CTRP1	4.8446	7.7487	3.5315	6.8394
OCUM-1	CTRP2	4.8646	7.5069	3.6603	13.2032
23132/87	CTRP2	4.8815	6.7865	4.0341	4.5719
NUGC-4	CTRP2; CTRP1	4.8976	6.6712	4.1147	4.2872
SNU-16	GDSC1	4.9627	6.3681	3.4893	1.6027
AGS	CTRP2; CTRP1	5.0537	9.4145	2.8768	9.1664
SNU-668	CTRP2	5.1432	6.7721	4.2615	3.1051
GSU	CTRP2	5.1495	5.8932	4.7041	1.2401
SH-10-TC	CTRP2; CTRP1	5.218	6.3596	4.5359	1.9077
ECC12	CTRP2	5.3055	6.3442	4.5971	1.4321
NUGC-3	CTRP2	5.3532	13.4872	1.0775	16.6896
MKN45	CTRP2	5.4095	6.8359	4.4317	1.9504
MKN1	CTRP2	5.4102	7.2315	4.2387	2.7427
SNU-216	CTRP2	5.4476	14.4435	0.6765	16.9715
NUGC-3	CTRP2	5.5203	6.9287	4.4632	1.6625
MKN1	CTRP2	5.5684	7.1316	4.3986	1.8541
SCH	GDSC1	5.6924	6.8668	3.6184	0.2758
OCUM-1	CTRP2	5.7341	9.8616	3.1836	6.5841
SNU-719	CTRP2	5.7675	9.9075	3.186	6.5188
NUGC-4	CTRP2; CTRP1	5.8108	22.1874	-2.8871	26.305
GSU	CTRP2	6.0385	6.7325	4.8188	0.0885
ECC12	CTRP2	6.1742	7.3308	4.6497	0.3876
MKN45	CTRP2	6.3883	7.5885	4.6429	0.2982
TGBC11TKB	GDSC1	6.3995	13.7179	0.966	14.7114
MKN7	GDSC1	6.5003	9.1669	3.0838	1.8168
HSC-39	GDSC1	6.5484	8.0332	3.5239	0.1922
IM95	CTRP2	6.6532	13.6887	1.9787	9.9747
SNU-719	CTRP2	6.9663	25.6673	-3.7124	25.9927
KE-39	CTRP2	7.223	19.3973	-0.4072	17.4151
SNU-668	CTRP2	7.8024	20.1244	-0.3389	16.2885
HuG1-N	CTRP2	7.8261	21.5374	-1.0143	18.2395
LMSU	CTRP2	8.3287	15.2581	2.3458	6.288
SNG-M	GDSC1	-2.1353	2.4747	-2.3494	69.0305
SNU-1077	CTRP2	4.5479	10.4914	1.8969	14.1365
SNG-M	CTRP2; CTRP1	4.7923	7.6284	3.5457	6.8877
SNU-1077	CTRP2	5.0151	6.1301	4.4769	2.4425
SNG-M	CTRP2; CTRP1	5.3773	7.0567	4.3113	2.576
SNU-685	CTRP2	8.8046	16.4437	2.09	6.6584

Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Thyroid Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
IHH-4	GDSC1	-3.795	3.3391	-4.336	74.0883
KMH-2	GDSC1	-0.8273	4.2867	-1.3492	57.1578
TT2609-C02	GDSC1	-0.2661	2.803	-0.392	52.965
8505C	GDSC1	-0.1229	3.6483	-0.4085	51.2636
8305C	GDSC1	0.0437	3.0723	-0.1043	49.5107
B-CPAP	GDSC1	0.3263	5.0708	-0.3454	47.03
ASH-3	GDSC1	0.9245	3.8636	0.6799	39.6267
ML-1 [Human leukemia]	GDSC1	0.9708	3.8816	0.7257	39.0834
CAL-62	GDSC1	1.3024	8.7767	-0.8898	41.4724
BHT-101	GDSC1	1.4379	7.8198	-0.3139	39.4077
CGTH-W-1	GDSC1	1.6641	8.6728	-0.485	38.6132
HTC-C3	GDSC1	2.0601	10.8227	-1.1377	38.2743
FTC-133	GDSC1	2.4497	26.1699	-8.402	44.4143
TT	GDSC1	4.0006	6.1621	2.9195	8.5156
8305C	CTRP2	4.1308	12.684	0.4389	20.5126
TT2609-C02	CTRP2	4.212	11.6159	1.0416	18.1725
WRO	GDSC1	4.2262	16.6407	-2.1328	32.7516
B-CPAP	CTRP2	4.3817	11.2327	1.382	16.5158
K5	GDSC1	4.6228	18.5028	-2.7391	32.9772
8505C	CTRP2	4.7259	10.3524	2.1205	12.8642
TT	CTRP2	4.9427	7.3301	3.8157	5.3642
8305C	CTRP2	4.9454	8.0762	3.4452	6.9153
B-CPAP	CTRP2	5.0393	6.5502	4.2872	3.1926
8505C	CTRP2	5.0518	7.5267	3.8094	5.1767
CGTH-W-1	CTRP2	5.1029	9.7496	2.7403	9.5613
CGTH-W-1	CTRP2	5.138	7.2388	4.0242	4.1111
FTC-238	CTRP2	5.24	13.2612	1.0978	15.8406
SW579	CTRP2	5.302	20.4019	-2.4208	26.1719
BHT-101	CTRP2	5.6874	11.6216	2.2751	10.4026
TT	CTRP2	5.8098	14.2234	1.0761	14.849
CAL-62	CTRP2	5.8115	20.6556	-2.1315	24.5571
CAL-62	CTRP2	5.9329	11.3618	2.5922	8.6883
FTC-133	CTRP2	5.9518	11.8775	2.3514	9.6355
BHT-101	CTRP2	6.0498	9.6195	3.5309	4.6627
ML-1 [Human leukemia]	CTRP2	7.0308	9.2941	4.2581	0.9315
ML-1 [Human leukemia]	CTRP2	7.389	15.7733	1.486	10.7244

Cancer Drug Sensitivity Data Curated from 85 Cell Line(s) in Upper Aerodigestive Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KON	GDSC1	-2.7772	6.737	-4.2898	64.5777
BB30-HNC	GDSC1	-1.1173	4.866	-1.8431	58.6655
JHU-029	GDSC1	-0.8281	8.5012	-2.9324	54.5331
BHY	GDSC1	-0.7953	6.0882	-1.922	55.5848
Ca9-22	GDSC1	-0.6053	4.7611	-1.2526	55.0886
JHU-011	GDSC1	-0.4364	4.7691	-1.0715	53.7473
SCC-4	GDSC1	-0.2842	11.6913	-3.8147	51.2477
PCI-04B	GDSC1	-0.007	5.7445	-0.9482	50.0562
OSC-20	GDSC1	0.1304	4.607	-0.4031	48.7712
LB771-HNC	GDSC1	0.1606	3.9995	-0.1899	48.3627
NCI-H3118	GDSC1	0.2397	5.4213	-0.5638	47.933
SNU-1214	CTRP2	0.857	13.4235	-2.9968	37.5081
CAL-27	GDSC1	0.901	7.8837	-0.8852	43.7492
HSC-3	GDSC1	0.9759	4.9707	0.3916	40.3188
PCI-06A	GDSC1	1.2591	5.8815	0.3459	38.5083
BICR 31	GDSC1	1.8809	14.1822	-2.9495	42.0072
FaDu	GDSC1	1.9096	5.3494	1.2478	30.2565
PE/CA-PJ34 (clone C12)	CTRP2	1.9382	11.0387	-0.8167	29.8539
UPCI-SCC-090	GDSC1	1.9538	7.6907	0.2596	34.6774
CAL-33	GDSC1	1.955	7.1685	0.5021	33.6941
BICR 10	GDSC1	2.0573	9.3643	-0.434	36.4706
KOSC-2	GDSC1	2.1428	8.7789	-0.071	34.8907
HSC-2	GDSC1	2.2603	3.6224	2.1895	22.2011
BB49-HNC	GDSC1	2.2954	8.6285	0.1472	33.3366
SCC-25	GDSC1	2.5731	7.8638	0.78	29.1814
OSC-19	GDSC1	2.7263	8.3067	0.7109	28.783
SCC-25	CTRP2	2.7562	8.154	1.3287	20.5885
SCC-9	GDSC1	2.8448	18.495	-4.2313	40.3872
BICR 22	GDSC1	2.8484	6.5579	1.6688	22.6678
HO-1-u-1	GDSC1	2.9158	6.2158	1.8962	20.7992
HO-1-N-1	GDSC1	2.9733	13.7111	-1.7356	35.9525
SCC-15	GDSC1	3.0517	13.3812	-1.5025	35.1215
Detroit 562	GDSC1	3.0967	15.0926	-2.3159	36.7328
PCI-15A	GDSC1	3.1562	7.2619	1.6217	21.5521
YD-10B	CTRP2	3.3113	15.4911	-1.6854	28.5988
HSC-2	CTRP1	3.4913	4.5714	3.4523	22.6765
JHU-022	GDSC1	3.5165	6.0731	2.5373	13.3919
BICR 78	GDSC1	3.6667	9.2016	1.1165	22.5112
SNU-46	CTRP2	3.7095	13.6424	-0.4122	24.2216
SAS	GDSC1	3.8506	17.749	-2.9994	35.6684
CAL-27	CTRP2	3.8975	11.6299	0.753	19.9294
CAL-33	CTRP2	3.9822	12.3191	0.4879	20.6745
HSC-4	GDSC1	4.0532	10.7314	0.6785	23.409
SNU-1214	CTRP2	4.0585	6.9707	3.1729	10.0017
SCC-9	CTRP1	4.4171	14.2675	-0.0906	35.2534
SCC-4	CTRP2	4.4325	9.9545	2.0625	13.713
SNU-46	CTRP2	4.4346	8.5585	2.7564	10.8568
FaDu	CTRP2	4.4578	8.6579	2.7282	11.6986
BICR 56	CTRP2	4.4988	16.2101	-0.9994	24.1983
Detroit 562	CTRP2	4.551	8.9338	2.6746	10.947
HSC-3	CTRP2	4.631	7.1213	3.6441	6.7353
HSC-2	CTRP2; CTRP1	4.6648	5.5651	4.4322	3.5055
PE/CA-PJ41 (clone D2)	CTRP2	4.7584	7.1173	3.7609	5.9734
YD-10B	CTRP2	4.8107	7.0662	3.8327	5.5629
SCC-25	CTRP2	4.9296	14.199	0.371	19.0553
YD-8	CTRP2	4.9512	20.2325	-2.6274	32.2665
YD-8	CTRP2	5.115	8.8502	3.2	7.6159
Detroit 562	CTRP2	5.319	7.1595	4.2061	3.0279
HSC-4	CTRP2	5.3245	7.4917	4.0456	3.6876
SCC-9	CTRP2; CTRP1	5.497	12.6442	1.6249	13.4118
SNU-1066	CTRP2	5.5491	19.2034	-1.619	23.7729
SNU-899	CTRP2	5.623	6.9593	4.5154	1.3233
BHY	CTRP2	5.648	20.5593	-2.216	25.0559
HSC-3	CTRP2	5.7314	7.5318	4.3161	1.9616
BICR 22	CTRP2	5.9187	23.6701	-3.5502	27.4217
PE/CA-PJ15	CTRP2	5.9273	17.414	-0.4209	19.6972
DOK	GDSC1	6.0159	15.3503	-0.0954	20.888
SNU-1041	CTRP2	6.0553	16.9933	-0.1099	18.49
SKN-3	GDSC1	6.1547	8.3342	3.2575	1.3373
SNU-1041	CTRP2	6.1679	9.8057	3.5225	4.5253
BHY	CTRP2	6.2464	11.3968	2.8057	7.3126
SNU-1066	CTRP2	6.2562	10.2403	3.3739	4.9971
PE/CA-PJ49	CTRP2	6.5425	13.9552	1.7675	10.9705
PE/CA-PJ15	GDSC1	6.7979	13.6365	1.2662	12.0913
PCI-30	GDSC1	6.8309	13.8891	1.1687	12.562
PCI-38	GDSC1	6.8314	24.2165	-3.8565	30.0176
BICR 31	CTRP2	6.9731	17.0798	0.5487	14.7235
BICR 18	CTRP2	7.1343	13.457	2.4265	7.5133
HSC-4	CTRP2	7.4427	19.205	-0.1502	17.1345
BICR 16	CTRP2	7.5145	20.434	-0.7014	17.8278
SNU-1076	CTRP2	7.7	15.4582	1.8497	8.9272
BICR 6	CTRP2	7.9858	20.1074	-0.1988	15.5759
SAT [Human HNSCC]	GDSC1	8.1713	19.688	-0.6994	18.2697
SNU-1076	CTRP2	8.438	22.5558	-1.0695	17.4684
SNU-899	CTRP2	10.8492	22.6683	0.4716	9.745

Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Urinary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
RT-112	GDSC1	-1.5483	7.3423	-3.2094	58.7717
SW1710	GDSC1	-0.5205	3.9314	-0.9149	54.9083
5637	GDSC1	-0.3659	5.4018	-1.2095	52.9342
639V	GDSC1	-0.2721	7.6607	-1.9972	51.712
647V	GDSC1	0.9899	12.0595	-2.7489	45.3436
BFTC-905	GDSC1	0.9995	3.7623	0.7872	38.5965
TCCSUP	GDSC1	1.2101	12.3027	-2.6564	44.326
J82	GDSC1	1.8509	3.0222	1.8323	26.9811
RT-4	CTRP2; CTRP1	2.1491	9.3436	0.1839	28.0191
HT-1197	GDSC1	2.7564	11.3711	-0.7671	34.3082
RT-4	GDSC1	2.78	7.9549	0.9322	27.3981
U-BLC1	CTRP2	3.1016	8.3857	1.5686	18.7802
HT-1197	CTRP2	3.1133	12.8355	-0.5581	26.0668
UM-UC-3	GDSC1	3.1375	4.9214	2.7109	13.7922
CAL-29	GDSC1	3.1898	15.8189	-2.5975	36.9563
JMSU-1	CTRP2	3.3848	11.7175	0.2408	22.904
HT-1376	GDSC1	3.4572	6.5844	2.2316	15.9516
5637	CTRP2; CTRP1	3.542	14.2216	-0.8408	25.9147
KU-19-19	GDSC1	3.5882	4.0116	3.5474	5.4156
RT-4	CTRP2; CTRP1	3.6139	5.4387	3.364	10.5116
KMBC-2	CTRP1	3.6939	5.3544	3.4792	21.1336
T24	GDSC1	3.8148	12.8083	-0.5595	29.5648
BC-3C	CTRP2	4.1902	6.9669	3.3033	9.153
JMSU-1	CTRP2	4.2809	6.5412	3.5928	7.7549
647V	CTRP2	4.3602	11.5602	1.2001	17.2559
253J	CTRP2	4.4359	9.6465	2.2185	13.0713
5637	CTRP2; CTRP1	4.4452	6.3874	3.833	6.468
KMBC-2	CTRP2; CTRP1	4.4458	6.0708	3.9817	5.8632
T24	CTRP2	4.7822	13.9604	0.3661	19.373
253J	CTRP2	4.8315	7.6028	3.5838	6.563
SCaBER	CTRP2	4.9672	13.183	0.9106	17.0705
UM-UC-3	CTRP2; CTRP1	4.9847	9.9375	2.5575	11.3743
BFTC-905	CTRP2	5.0396	6.1242	4.5005	2.2956
253J-BV	CTRP2	5.1222	15.7697	-0.2536	20.7158
639V	CTRP2	5.1515	6.3575	4.4748	2.1954
RT-112	CTRP2	5.1777	19.22	-1.9326	25.2639
SW780	GDSC1	5.2792	6.9946	3.3865	1.7326
VM-CUB-1	CTRP2	5.3164	8.6124	3.4817	6.0618
CAL-29	CTRP2	5.3514	9.6648	2.9848	8.0775
253J-BV	CTRP2	5.3962	8.9302	3.3863	6.3187
HT-1376	CTRP2; CTRP1	5.4008	8.9772	3.3769	6.4298
UM-UC-3	CTRP2; CTRP1	5.4357	8.2158	3.7824	4.6762
SW1710	CTRP2	5.5128	9.0051	3.4396	5.8934
SW1710	CTRP2	5.5639	7.8074	4.0683	3.2022
TCCSUP	CTRP2	5.576	9.354	3.315	6.3046
HT-1376	CTRP2; CTRP1	5.5788	11.2424	2.389	10.914
BFTC-905	CTRP2	5.6903	7.2815	4.4074	1.6573
KU-19-19	CTRP2	5.7432	8.5871	3.8163	3.9595
KU-19-19	CTRP2	5.8418	13.9841	1.2204	14.2549
639V	CTRP2	6.1605	7.8476	4.4273	1.0747
RT-112	CTRP2	6.1864	9.6477	3.6109	4.1448
TCCSUP	CTRP2	6.8861	18.4507	-0.1926	17.3057
J82	CTRP2	6.9339	11.9995	2.9873	5.5973
UM-UC-1	CTRP2	7.4777	21.6459	-1.326	19.6512
VM-CUB-1	CTRP2	8.8189	21.7633	-0.4169	15.0265

Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Urogenital System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KGN	GDSC1	-2.1727	7.8196	-4.0609	61.0549
NT2-D1	GDSC1	-1.9081	2.7899	-2.1621	66.957
CAL-39	GDSC1	0.0008	5.3674	-0.8017	49.9931
NCC-IT	GDSC1	0.2582	7.5434	-1.3962	48.2599
PA-1	GDSC1	0.3108	2.2426	0.2847	46.1984
DoTc2 4510	GDSC1	0.3946	4.3601	-0.0386	46.0423
SW954	GDSC1	0.7993	8.6499	-1.3335	44.942
BPH-1	GDSC1	0.9231	7.1743	-0.5498	43.0433
SW962	GDSC1	1.1246	8.7343	-1.0467	42.725
C-33 A	GDSC1	1.1655	7.7096	-0.5387	41.5342
LB831-BLC	GDSC1	1.3158	5.1542	0.6907	36.7899
SiSo	GDSC1	1.3162	5.7751	0.4493	37.7572
OVMIU	GDSC1	1.8471	8.54	-0.2436	36.9665
HeLa	GDSC1	2.1746	3.71	2.0789	23.4349
ME-180	GDSC1	2.3536	3.9097	2.227	21.4053
OMC-1 [Human cervical carcinoma]	GDSC1	2.5577	7.4994	0.9397	28.4387
JEG-3	GDSC1	2.5748	4.3564	2.3346	19.4239
Ca Ski	GDSC1	2.8307	10.5476	-0.293	32.4763
HEC-1	GDSC1	2.8881	4.5104	2.617	15.7475
MS751	GDSC1	3.0026	10.5668	-0.1477	31.2223
DSH1	GDSC1	3.0877	9.4987	0.4577	28.3468
SKN	GDSC1	3.3311	7.0954	1.8648	19.1351
C-4-I	GDSC1	3.4304	11.1268	-0.0485	29.0966
SW756	GDSC1	3.6042	9.8573	0.7353	24.8401
SiHa	GDSC1	4.0122	6.0524	2.9839	7.9672
HeLa	CTRP2	4.0177	4.9241	3.9543	7.5631
HT-3	GDSC1	4.6122	7.7402	2.6124	8.8747
JAR	GDSC1	4.6488	6.3336	3.3195	3.4218
SKG-IIIa	GDSC1	4.8537	10.1953	1.5819	15.4078
NEC8	GDSC1	5.6537	20.894	-3.1115	31.1243
HeLa	CTRP2	5.7035	7.3974	4.3614	1.82

References

• [1] ClinicalTrials.gov (NCT00093990) Tipifarnib Versus Best Supportive Care in the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML). U.S. National Institutes of Health.
• [2] Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
• [3] Emerging therapies for multiple myeloma. Expert Opin Emerg Drugs. 2009 Mar;14(1):99-127.
• [4] Tipifarnib in the treatment of newly diagnosed acute myelogenous leukemia. Biologics. 2008 Sep;2(3):491-500.
• [5] Pharmacogenetics of tipifarnib (R115777) transport and metabolism in cancer patients. Invest New Drugs. 2004 Aug;22(3):285-9.
• [6] Genetic disruption of the PI3K regulatory subunits, p85, p55, and p50, normalizes mutant PTPN11-induced hypersensitivity to GM-CSF. Haematologica. 2012 Jul;97(7):1042-7. doi: 10.3324/haematol.2011.046896. Epub 2012 Feb 7.
• [7] Ras homologue enriched in brain is a critical target of farnesyltransferase inhibitors in non-small cell lung cancer cells. Cancer Lett. 2010 Nov 1;297(1):117-25. doi: 10.1016/j.canlet.2010.05.004.
• [8] Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells. Blood. 2005 Jun 15;105(12):4759-66. doi: 10.1182/blood-2004-11-4307. Epub 2005 Feb 22.