Details of the Drug

General Information of Drug (ID: DMF3DZX)

Drug Name
CI-1040
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 478.7
Logarithm of the Partition Coefficient (xlogp) 5.6
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C17H14ClF2IN2O2
IUPAC Name
2-(2-chloro-4-iodoanilino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide
Canonical SMILES
C1CC1CONC(=O)C2=C(C(=C(C=C2)F)F)NC3=C(C=C(C=C3)I)Cl
InChI
InChI=1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24)
InChIKey
GFMMXOIFOQCCGU-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
6918454
ChEBI ID
CHEBI:91353
CAS Number
212631-79-3
UNII
R3K9Y00J04
DrugBank ID
DB12429
TTD ID
D0B9BU
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Checkpoint kinase-1 (CHK1) TTTU902 CHK1_HUMAN Inhibitor [2]
Extracellular signal-regulated kinase 2 (ERK2) TT4TQBX MK01_HUMAN Inhibitor [2]
Glycogen synthase kinase-3 beta (GSK-3B) TTRSMW9 GSK3B_HUMAN Inhibitor [2]
LCK tyrosine protein kinase (LCK) TT860QF LCK_HUMAN Inhibitor [2]
MAP kinase p38 (MAPK12) TTYT93M MK12_HUMAN Inhibitor [2]
MAPK/ERK kinase kinase 1 (MAP3K1) TTQBCEJ M3K1_HUMAN Inhibitor [1]
MAPK/ERK kinase kinase 2 (MAP3K2) TTK1N5G M3K2_HUMAN Inhibitor [1]
Protein kinase C alpha (PRKCA) TTFJ8Q1 KPCA_HUMAN Inhibitor [2]
RAC-alpha serine/threonine-protein kinase (AKT1) TTWTSCV AKT1_HUMAN Inhibitor [2]
Rho-associated protein kinase 1 (ROCK1) TTZN7RP ROCK1_HUMAN Inhibitor [2]
Ribosomal protein S6 kinase beta-1 (S6K1) TTG0U4H KS6B1_HUMAN Inhibitor [2]
Serine/threonine-protein kinase Sgk1 (SGK1) TTTV8EJ SGK1_HUMAN Inhibitor [2]
Stress-activated protein kinase 2a (p38 alpha) TTQBR95 MK14_HUMAN Inhibitor [2]
Stress-activated protein kinase 2b (p38 beta) TT73U6C MK11_HUMAN Inhibitor [2]
Stress-activated protein kinase JNK1 (JNK1) TT0K6EO MK08_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Aryl hydrocarbon receptor (AHR) OTFE4EYE AHR_HUMAN Gene/Protein Processing [3]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Protein Interaction/Cellular Processes [4]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Post-Translational Modifications [5]
Caveolin-1 (CAV1) OTEZUR1L CAV1_HUMAN Gene/Protein Processing [6]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Gene/Protein Processing [7]
Cytochrome P450 3A5 (CYP3A5) OTSXFBXB CP3A5_HUMAN Gene/Protein Processing [7]
Cytochrome P450 3A7 (CYP3A7) OTTCDHHM CP3A7_HUMAN Gene/Protein Processing [7]
Dual specificity mitogen-activated protein kinase kinase 1 (MAP2K1) OT4Y9NQI MP2K1_HUMAN Gene/Protein Processing [8]
Epidermal growth factor receptor (EGFR) OTAPLO1S EGFR_HUMAN Post-Translational Modifications [9]
Interstitial collagenase (MMP1) OTI4I2V1 MMP1_HUMAN Gene/Protein Processing [10]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Glycogen synthase kinase-3 beta (GSK-3B) DTT GSK3B 1.26E-01 -0.23 -0.77
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 3.2673 5.1035 2.3852 7.587
H-EMC-SS GDSC1 0.6365 2.0919 0.6139 33.7073
HOS GDSC1 1.9192 6.4916 0.4569 27.1772
U2OS GDSC1 2.2862 5.2958 1.3793 19.4304
A-673 GDSC1 2.8337 5.3989 1.8529 13.4604
ES1 GDSC1 2.9903 4.6973 2.3415 9.0225
ES4 GDSC1 3.0495 6.1592 1.6703 13.9718
TC-71 GDSC1 3.1911 4.0457 2.846 4.2557
SJSA-1 GDSC1 3.2163 7.2011 1.2936 16.0935
CAL-72 GDSC1 3.3449 7.443 1.2805 15.703
EW-16 GDSC1 3.3499 5.6408 2.1857 8.8543
EW-11 GDSC1 3.4205 5.687 2.2205 8.3313
NOS-1 [Human HNSCC] GDSC1 3.4435 8.7463 0.7104 19.1357
ES8 GDSC1 3.4491 5.3387 2.4175 6.685
ES7 GDSC1 3.5178 6.0088 2.138 8.6415
EW-1 GDSC1 3.5693 6.6023 1.8831 10.4392
ES5 GDSC1 3.677 5.8063 2.3618 6.3774
HuO9 GDSC1 3.6829 5.9499 2.2953 6.8758
CHSA0011 GDSC1 3.7237 8.8492 0.8856 17.0236
MG-63 GDSC1 3.8073 7.785 1.4809 12.6471
G-292 clone A141B1 GDSC1 3.8583 6.4792 2.165 7.3444
CHSA8926 GDSC1 3.8861 6.1285 2.3565 5.7944
EW-22 GDSC1 3.9139 6.5022 2.1941 6.9565
CHSA0108 GDSC1 4.0356 10.3421 0.3874 19.0018
SK-PN-DW GDSC1 4.1354 8.3545 1.4472 11.8451
ES6 GDSC1 4.1443 6.5469 2.3326 5.2741
MHH-ES-1 GDSC1 4.1997 6.1549 2.553 3.5246
NY GDSC1 4.327 7.6117 1.9459 7.6624
SaOS-2 GDSC1 4.3451 7.9302 1.8048 8.6477
CAL-78 GDSC1 4.3732 6.1746 2.6472 2.5088
CADO-ES1 GDSC1 4.56 8.6791 1.5917 9.5911
HuO-3N1 GDSC1 4.9627 9.5153 1.4628 9.4306
EW-24 GDSC1 5.3822 6.9544 2.8062 0.4887
SK-ES-1 GDSC1 5.6422 7.3342 2.7695 0.4618
EW-7 GDSC1 5.6631 17.2652 -1.8079 24.0162
EW-13 GDSC1 6.2112 21.9737 -3.7192 28.1342
EW-3 GDSC1 6.8442 21.881 -3.211 25.512
EW-18 GDSC1 7.2671 19.4499 -1.7383 20.0747
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 157 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 3.854 5.283 2.7415 2.9715
SKM-1 GDSC1 -6.1083 3.1305 -6.9178 77.0542
JURL-MK1 GDSC1 -4.2108 1.7398 -4.5272 75.5236
KMOE-2 GDSC1 -3.1012 0.8973 -3.2049 72.9631
NB4 GDSC1 -2.7876 3.0607 -3.2761 66.2608
NOMO-1 GDSC1 -2.2974 4.51 -3.1717 61.3356
EoL-1 GDSC1 -2.2798 5.7332 -3.5854 59.8782
HL-60 GDSC1 -1.9191 4.9451 -2.9108 58.6874
KG-1 GDSC1 -1.7729 8.2928 -4.0884 55.6
OCI-AML-3 GDSC1 -1.4599 5.5513 -2.6388 55.4136
OCI-AML-2 GDSC1 -1.2588 6.8672 -2.9495 53.5772
PL-21 GDSC1 -1.1067 7.9402 -3.2482 52.414
H9 GDSC1 -0.8475 7.224 -2.6712 51.0513
ML-2 GDSC1 -0.6001 5.5866 -1.7355 49.4046
Ku812 GDSC1 -0.4853 5.1576 -1.4469 48.4293
LAMA-84 GDSC1 -0.2112 6.8109 -1.835 46.7644
MOLT-13 GDSC1 0.0761 10.0934 -3.0414 46.1182
Kasumi-1 GDSC1 0.1336 8.2552 -2.1286 45.0049
KY821 GDSC1 0.241 8.159 -1.9771 44.2304
EM-2 GDSC1 0.5145 9.9066 -2.5268 43.527
ALL-PO GDSC1 0.6582 8.2778 -1.6179 41.3872
MV4-11 GDSC1 0.7191 8.2202 -1.531 40.89
NKM-1 GDSC1 0.7458 17.8067 -6.1654 45.526
BV-173 GDSC1 0.7749 7.5954 -1.1854 39.8137
SUP-B15 GDSC1 0.9113 7.5564 -1.0319 38.6656
NCI-H929 GDSC1 0.9287 4.1447 0.4469 32.7806
ME1 GDSC1 0.9688 15.4385 -4.7941 43.9621
KOPN-8 GDSC1 0.9996 6.4248 -0.4253 36.2513
OCI-Ly19 GDSC1 1.225 4.9734 0.4392 31.0233
YT GDSC1 1.329 10.979 -2.2723 39.4544
MEG-01 GDSC1 1.3415 6.8037 -0.2563 33.6756
DoHH2 GDSC1 1.3737 8.4758 -1.0162 36.2103
A4/Fukuda GDSC1 1.3745 8.6076 -1.0787 36.395
RPMI-8866 GDSC1 1.3979 12.8516 -3.128 40.6123
RS4;11 GDSC1 1.5701 27.2846 -10.1488 45.2578
OCI-AML-5 GDSC1 1.6137 4.6661 0.9741 25.62
RPMI-8226 GDSC1 1.8616 19.0329 -5.7814 42.1135
SU-DHL-5 GDSC1 1.9887 5.8979 0.8048 24.7548
MOLM-16 GDSC1 1.9921 14.4878 -3.4046 38.9033
CCRF-CEM GDSC1 2.2005 17.9861 -4.9645 40.3535
JJN-3 GDSC1 2.2556 13.4227 -2.6424 36.59
SU-DHL-6 GDSC1 2.2574 4.7168 1.6166 17.8489
U266B1 GDSC1 2.276 7.9201 0.102 27.3803
K-562 GDSC1 2.391 8.5296 -0.0933 27.8309
Karpas-620 GDSC1 2.4113 6.0402 1.1453 20.4957
Karpas-231 GDSC1 2.4196 3.5492 2.267 12.3036
ST486 GDSC1 2.4597 6.0823 1.1707 20.1007
MOLT-16 GDSC1 2.4702 9.5806 -0.5428 29.4965
NU-DUL-1 GDSC1 2.4825 5.0394 1.6922 16.2247
697 GDSC1 2.5639 8.7571 -0.0506 26.8766
KE-37 GDSC1 2.58 9.1778 -0.2452 27.7336
DND-41 GDSC1 2.6048 7.2031 0.7555 22.2025
HAL-01 GDSC1 2.6237 17.4274 -4.3208 38.3099
OCI-Ly7 GDSC1 2.6427 3.478 2.5328 9.2265
Namalwa GDSC1 2.6782 3.7149 2.4834 9.3892
JSC-1 GDSC1 2.6907 10.267 -0.6897 29.1934
MY-M12 GDSC1 2.6959 9.8617 -0.4832 28.3145
Farage GDSC1 2.7116 7.7716 0.57 22.8798
Karpas-1106P GDSC1 2.7256 7.6764 0.6297 22.4611
GA-10 GDSC1 2.7364 4.9441 1.983 12.8831
KCL-22 GDSC1 2.7704 4.7235 2.1214 11.672
L-1236 GDSC1 2.7799 5.3068 1.8481 13.7259
KMS-12-BM GDSC1 2.8162 3.9551 2.525 8.3937
OCI-M1 GDSC1 2.8541 4.6393 2.2419 10.3775
SUP-M2 GDSC1 2.8967 4.1001 2.5394 7.906
RL GDSC1 2.908 7.4827 0.8872 20.0832
LC4-1 GDSC1 2.9922 10.9077 -0.7491 28.2605
JVM-3 GDSC1 3.002 17.1211 -3.846 36.4628
CESS GDSC1 3.0132 3.9798 2.7102 6.0728
BL-41 GDSC1 3.0187 3.9953 2.7082 6.0631
U-698-M GDSC1 3.0805 6.0245 1.7645 13.1346
SUP-HD1 GDSC1 3.1219 7.0424 1.2925 16.4644
HH [Human lymphoma] GDSC1 3.1567 11.8296 -1.0704 28.8917
HDLM-2 GDSC1 3.2057 4.5793 2.594 6.1762
MM1.S GDSC1 3.2064 16.2801 -3.2537 34.7498
WSU-NHL GDSC1 3.2463 5.6357 2.1014 9.8936
MOLP-8 GDSC1 3.2844 15.2793 -2.688 33.2657
EJM GDSC1 3.2927 5.7933 2.0618 10.0317
Jiyoye GDSC1 3.3026 4.4899 2.7218 4.8036
MC116 GDSC1 3.3287 4.2845 2.8462 3.7272
MOLM-13 GDSC1 3.3433 5.4433 2.279 8.1453
WSU-DLCL2 GDSC1 3.3498 7.0309 1.4906 14.1698
ATN-1 GDSC1 3.3691 6.9696 1.5372 13.7551
P32/ISH GDSC1 3.3817 4.4034 2.8302 3.6673
RCH-ACV GDSC1 3.4176 6.0344 2.0445 9.7167
L-540 GDSC1 3.426 7.9129 1.1126 16.5732
AMO1 GDSC1 3.4724 9.1827 0.516 20.2091
IM-9 GDSC1 3.4955 7.1662 1.5425 13.2617
MOLT-4 GDSC1 3.5577 10.5746 -0.1098 23.3044
HEL GDSC1 3.5589 6.2788 2.0361 9.2948
Sc-1 GDSC1 3.5873 4.8921 2.7455 3.671
SR GDSC1 3.5965 5.7068 2.3499 6.7251
Granta-519 GDSC1 3.6018 5.2093 2.6001 4.756
ALL-SIL GDSC1 3.6136 6.4941 1.9719 9.6076
OPM-2 GDSC1 3.6581 7.0249 1.7426 11.2074
BC-1 GDSC1 3.6768 6.6018 1.9676 9.4321
GR-ST GDSC1 3.724 20.9055 -5.1371 36.5568
CRO-AP2 GDSC1 3.7333 6.7093 1.9577 9.3244
P12-Ichikawa GDSC1 3.7726 11.072 -0.1842 22.9217
HC-1 GDSC1 3.8059 7.6145 1.5645 12.0419
HT GDSC1 3.813 9.1284 0.8171 17.1562
Loucy GDSC1 3.8299 5.937 2.4097 5.5483
A3/Kawakami GDSC1 3.8586 5.3836 2.6967 3.292
EB2 GDSC1 3.9001 5.6646 2.5904 3.9808
LP-1 GDSC1 3.9064 5.6932 2.5809 4.0355
BE-13 GDSC1 3.9417 27.2006 -8.105 39.3798
CTV-1 GDSC1 3.9529 10.2424 0.3725 19.3618
CTB-1 GDSC1 3.9537 10.4545 0.2675 19.949
MHH-PREB-1 GDSC1 4.0149 11.602 -0.2557 22.4557
Raji GDSC1 4.0323 7.1773 1.9494 8.4665
DG-75 GDSC1 4.1148 7.0075 2.0908 7.166
Daudi GDSC1 4.1703 8.0494 1.6225 10.4788
CA46 GDSC1 4.1818 6.9258 2.1764 6.3408
MHH-CALL-2 GDSC1 4.1923 9.6809 0.8355 15.7915
VAL GDSC1 4.198 6.4689 2.405 4.6038
NALM-6 GDSC1 4.2493 12.5596 -0.5486 23.0642
VL51 GDSC1 4.2732 9.9442 0.7663 15.9713
SK-MM-2 GDSC1 4.3239 6.3905 2.5204 3.4807
Karpas-299 GDSC1 4.3243 12.1771 -0.3006 21.6784
RPMI-6666 GDSC1 4.3518 9.4803 1.0532 13.8874
Karpas-45 GDSC1 4.3648 11.4477 0.092 19.5705
RPMI-8402 GDSC1 4.3709 7.1809 2.181 5.8189
ARH-77 GDSC1 4.5828 9.1149 1.3971 10.8891
JVM-2 GDSC1 4.6052 15.5245 -1.7457 26.6331
L-363 GDSC1 4.6105 21.0163 -4.4757 33.349
CML-T1 GDSC1 4.6493 11.9222 0.0716 18.8091
WIL2 NS GDSC1 4.6832 10.7709 0.662 15.3717
QIMR-WIL GDSC1 4.7469 15.6779 -1.7124 26.1211
DEL GDSC1 4.8613 14.6086 -1.0955 23.5384
THP-1 GDSC1 4.8709 10.3334 1.0081 12.6831
SU-DHL-4 GDSC1 4.9162 6.0828 2.9409 0.3217
SUP-B8 GDSC1 4.9273 6.8399 2.6523 1.5971
SUP-T1 GDSC1 5.0637 12.9486 -0.1283 18.6384
JeKo-1 GDSC1 5.0928 14.3421 -0.791 21.6331
EHEB GDSC1 5.1364 14.14 -0.6595 20.94
RC-K8 GDSC1 5.1587 6.9802 2.7033 1.0728
P31/FUJ GDSC1 5.268 11.0804 0.9201 12.1843
L-428 GDSC1 5.2885 14.1589 -0.5578 20.0675
MLMA GDSC1 5.2962 15.7636 -1.34 23.286
TK [Human B-cell lymphoma] GDSC1 5.2991 6.9621 2.7701 0.6697
DB GDSC1 5.3129 22.3453 -4.5857 31.932
ROS-50 GDSC1 5.3503 9.2362 1.8354 6.0218
Ramos.2G6.4C10 GDSC1 5.6039 21.1445 -3.7664 29.597
P30/OHK GDSC1 5.7199 14.0927 -0.2196 17.3355
KMS-11 GDSC1 5.8357 14.4022 -0.289 17.379
GDM-1 GDSC1 6.0237 7.6068 2.8141 0.2094
MN-60 GDSC1 6.0537 8.1491 2.6341 0.6609
Reh GDSC1 6.0724 16.0697 -0.9308 19.6734
Mono-Mac-6 GDSC1 6.0735 20.6448 -3.167 27.0814
Karpas-422 GDSC1 6.2138 19.8473 -2.6721 25.4085
KM-H2 GDSC1 6.3285 13.4101 0.5091 12.063
BALL-1 GDSC1 6.3492 18.3598 -1.8478 22.4954
TUR GDSC1 6.577 16.7684 -0.9201 18.4337
SU-DHL-16 GDSC1 6.9512 19.1062 -1.7886 20.9318
Jurkat GDSC1 7.267 19.4645 -1.7454 20.1
PF-382 GDSC1 7.5009 19.0723 -1.402 18.3473
CMK GDSC1 7.6515 19.5768 -1.5423 18.5652
⏷ Show the Full List of 157 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-GT-4 GDSC1 0.6327 6.2985 -0.743 39.4785
TE-12 GDSC1 2.1896 7.6732 0.1431 27.5669
OACP4 C GDSC1 2.4896 6.8272 0.8351 22.206
ESO-51 GDSC1 2.7581 14.2302 -2.6089 34.7813
KYAE-1 GDSC1 2.9918 10.7683 -0.6798 27.9801
KYSE-220 GDSC1 3.153 7.8799 0.9007 19.0195
HCE-4 GDSC1 3.3749 6.4006 1.8266 11.5533
KYSE-50 GDSC1 4.1871 6.4638 2.4003 4.6655
FLO-1 GDSC1 4.6626 9.9532 1.0463 13.0193
ESO-26 GDSC1 5.0164 12.1647 0.2208 16.9463
OACM5.1 C GDSC1 5.3321 9.9887 1.4778 8.4383
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 3.7486 7.277 1.6878 11.3181
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHP-212 GDSC1 -4.8949 1.8162 -5.2837 77.3744
SK-N-AS GDSC1 0.374 6.3934 -1.0504 41.8673
NB69 GDSC1 0.4638 5.8211 -0.7114 40.4572
SK-N-BE(2)-M17 GDSC1 1.6744 5.5543 0.6495 27.3197
LA-N-6 GDSC1 1.9483 9.0462 -0.7525 32.5964
SJNB-5 GDSC1 2.074 6.1121 0.7871 24.4465
MHH-NB-11 GDSC1 2.0978 9.9032 -1.0373 32.9392
NH-12 GDSC1 2.2565 7.2576 0.4083 25.8316
SJNB-14 GDSC1 2.5219 4.2856 2.0782 13.1509
KP-N-YS GDSC1 2.5671 21.2865 -6.2968 40.754
NB(TU)1 GDSC1 2.6337 4.8949 1.9078 13.9131
TGW GDSC1 2.6655 4.2424 2.2432 11.2274
SJNB-7 GDSC1 2.8279 5.0462 2.0199 12.2023
SK-N-FI GDSC1 2.9121 7.0956 1.0835 18.7584
SK-N-SH GDSC1 2.9447 4.6833 2.306 9.4914
CHP-126 GDSC1 2.9881 4.0158 2.6687 6.5035
Kelly GDSC1 3.0754 4.8465 2.3455 8.6418
SK-N-MC-IXC GDSC1 3.1391 3.83 2.9031 4.0313
SJNB-13 GDSC1 3.2764 4.4059 2.7415 4.745
GI-ME-N GDSC1 3.2977 11.1677 -0.6212 26.5989
NB1 GDSC1 3.3666 5.4267 2.3065 7.8457
SJNB-17 GDSC1 3.3949 5.9395 2.0734 9.5719
KP-N-YN GDSC1 3.6003 5.3366 2.5362 5.2585
SiMa GDSC1 3.6204 5.7508 2.3463 6.6765
SJNB-10 GDSC1 3.7214 11.7373 -0.5576 24.8332
GOTO GDSC1 4.336 8.4286 1.5564 10.4692
SJNB-12 GDSC1 4.4484 6.8354 2.3916 4.1176
SJNB-6 GDSC1 4.4557 6.8556 2.3868 4.1358
SK-N-DZ GDSC1 4.6135 10.2296 0.8764 14.2506
IMR-5 GDSC1 6.3522 15.5964 -0.5105 17.1631
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 2.4919 11.9488 -1.7014 33.4146
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 GDSC1 -3.2857 -0.0426 -3.3189 76.7371
MDA-MB-231 GDSC1 2.0751 5.9014 0.8878 23.8007
MDA-MB-468 GDSC1 2.0895 4.8189 1.4003 20.2363
HCC70 GDSC1 2.3504 12.0506 -1.8763 34.4338
HCC1143 GDSC1 2.3621 10.12 -0.9067 31.3632
Hs 578T GDSC1 2.9838 10.7569 -0.6809 28.015
MDA-MB-175-VII GDSC1 2.9972 4.6182 2.3866 8.6433
MDA-MB-361 GDSC1 3.0442 4.46 2.5076 7.5041
MFM-223 GDSC1 3.152 3.8231 2.9187 3.8537
CAMA-1 GDSC1 3.1616 5.3415 2.1756 9.6338
CAL-51 GDSC1 3.2347 4.0932 2.8614 3.9604
HCC1937 GDSC1 3.2408 7.6403 1.0947 17.3861
HDQ-P1 GDSC1 3.2722 8.4778 0.7025 19.8239
HCC1806 GDSC1 3.2787 4.4977 2.6976 5.0827
Evsa-T GDSC1 3.3273 4.3039 2.8354 3.8177
CAL-120 GDSC1 3.3493 4.9197 2.5458 6.0224
MDA-MB-436 GDSC1 3.412 6.0844 2.015 9.9663
MDA-MB-157 GDSC1 3.4217 11.1957 -0.5321 25.7674
HCC1428 GDSC1 3.4619 4.5729 2.8089 3.5672
EFM-19 GDSC1 3.4747 5.1445 2.5346 5.6774
MCF-7 GDSC1 3.5368 5.0832 2.6133 4.8568
MDA-MB-330 GDSC1 3.6693 5.3427 2.5844 4.6725
MDA-MB-415 GDSC1 3.7071 5.4662 2.5514 4.8161
CAL-85-1 GDSC1 3.7231 7.3625 1.6255 11.8655
MDA-MB-453 GDSC1 3.7286 5.2455 2.6744 3.809
OCUB-M GDSC1 3.789 5.7826 2.4558 5.3122
HCC2157 GDSC1 3.827 6.552 2.1061 7.8916
UACC-893 GDSC1 3.8491 7.1866 1.8094 10.0815
AU565 GDSC1 3.8537 6.4359 2.1828 7.2212
HCC38 GDSC1 3.8992 6.1853 2.3382 5.8974
JIMT-1 GDSC1 3.9096 10.7159 0.1026 20.992
T-47D GDSC1 3.9273 5.8048 2.5416 4.2764
EFM-192A GDSC1 4.0032 6.4097 2.3024 5.8781
ZR-75-30 GDSC1 4.0163 6.1473 2.4376 4.8225
MRK-nu-1 GDSC1 4.0883 6.2196 2.4512 4.5358
HCC202 GDSC1 4.2643 7.4313 1.9897 7.5085
HCC1395 GDSC1 4.2965 7.0107 2.2128 5.7725
BT-20 GDSC1 4.321 11.3968 0.0839 19.7512
HCC1419 GDSC1 4.6977 12.1672 -0.0131 19.1071
BT-474 GDSC1 4.9727 6.297 2.885 0.4719
HCC1954 GDSC1 5.1499 13.1784 -0.1784 18.6475
BT-549 GDSC1 5.2726 7.6189 2.4991 1.9907
HCC2218 GDSC1 5.6346 20.9453 -3.6445 29.25
COLO 824 GDSC1 6.0677 8.1804 2.6282 0.672
HCC1569 GDSC1 6.2 8.4098 2.5965 0.6985
HCC1187 GDSC1 6.5419 17.0927 -1.0999 19.2544
BT-483 GDSC1 7.0672 17.1986 -0.7983 16.8263
HCC1500 GDSC1 7.2074 22.5729 -3.289 24.9648
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ONS-76 GDSC1 0.5399 3.3815 0.2693 36.2713
GaMG GDSC1 1.0603 14.8048 -4.3983 43.3188
D-423MG GDSC1 1.3654 8.0952 -0.842 35.7028
8-MG-BA GDSC1 1.5714 16.8008 -4.9266 42.1675
D-566MG GDSC1 1.8161 9.0152 -0.8598 33.585
H4 GDSC1 2.1974 6.0983 0.913 23.0485
LN-229 GDSC1 2.3255 9.1557 -0.4619 29.7753
SW1088 GDSC1 2.3313 11.0221 -1.382 33.0874
D-263MG GDSC1 2.3682 14.7313 -3.1958 37.2815
DBTRG-05MG GDSC1 2.5427 13.0723 -2.2169 34.598
MOG-G-UVW GDSC1 2.7068 8.5614 0.1734 25.1312
MOG-G-CCM GDSC1 2.746 4.9901 1.9699 12.9406
YKG-1 GDSC1 2.8445 4.898 2.1076 11.4553
U-118MG GDSC1 2.8514 4.1919 2.4519 8.7804
T98G GDSC1 2.953 6.5723 1.3799 16.5075
D-336MG GDSC1 3.0408 5.2174 2.1308 10.4593
KALS-1 GDSC1 3.0661 7.14 1.1957 17.3657
YH-13 GDSC1 3.0811 5.2908 2.1303 10.3025
SF126 GDSC1 3.1226 8.679 0.4755 21.7671
SF295 GDSC1 3.14 5.4348 2.1103 10.2286
DK-MG GDSC1 3.1649 8.0652 0.8182 19.506
KS-1 [Human Krukenberg tumour] GDSC1 3.1679 12.8756 -1.5838 30.6116
AM-38 GDSC1 3.1844 8.7188 0.5081 21.3364
U-251MG GDSC1 3.2021 5.5543 2.1044 10.0364
SF268 GDSC1 3.2854 8.598 0.6534 20.077
A-172 GDSC1 3.3627 10.9263 -0.4464 25.5987
SF539 GDSC1 3.5003 7.2037 1.5276 13.3543
U-87MG ATCC GDSC1 3.5028 9.3864 0.439 20.5489
D-247MG GDSC1 3.5653 8.6389 0.8635 17.7238
Becker GDSC1 3.5815 6.6173 1.8853 10.3807
LNZTA3WT4 GDSC1 3.5818 5.1081 2.6351 4.5451
SK-MG-1 GDSC1 3.6201 6.3953 2.0261 9.1675
M059J GDSC1 3.669 5.2756 2.6171 4.4206
PFSK-1 GDSC1 3.672 6.7034 1.9134 9.8632
LN-18 GDSC1 3.6884 4.7029 2.9078 2.153
D-502MG GDSC1 3.7372 10.3982 0.1236 21.4699
SNB-75 GDSC1 3.756 10.4461 0.1148 21.4513
CAS-1 GDSC1 3.8585 8.7845 1.0239 15.6559
Daoy GDSC1 3.8932 12.5606 -0.8304 25.4204
NMC-G1 GDSC1 3.9275 11.3191 -0.1839 22.3956
SW1783 GDSC1 4.035 6.3088 2.3729 5.2596
GB-1 GDSC1 4.1694 7.8349 1.7268 9.7195
42-MG-BA GDSC1 4.4545 12.4006 -0.3116 21.327
Hs 683 GDSC1 4.5687 7.5984 2.112 5.8383
Onda 10 GDSC1 4.5887 10.3647 0.7924 14.8501
KNS-81-FD GDSC1 4.5942 10.5278 0.7165 15.3019
LN-405 GDSC1 4.6688 7.3291 2.2984 4.2954
D-542MG GDSC1 4.9405 6.4457 2.8156 0.7706
D-392MG GDSC1 5.0046 14.4884 -0.9286 22.4585
GI-1 GDSC1 5.289 12.5328 0.235 16.12
KNS-42 GDSC1 5.2939 11.7982 0.5933 14.0866
Onda 11 GDSC1 5.3483 15.754 -1.2968 22.9841
D283 Med GDSC1 5.3581 6.8698 2.8275 0.4346
KINGS-1 GDSC1 5.436 12.1228 0.5343 14.0584
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1 2.8336 4.921 2.0863 11.6664
ETK-1 GDSC1 3.7407 10.6739 -0.0112 22.163
TGBC24TKB GDSC1 3.8528 7.3427 1.735 10.6281
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RL95-2 GDSC1 -0.5646 6.9728 -2.2703 49.2559
AN3-CA GDSC1 2.7691 6.9142 1.0466 19.6018
MFE-319 GDSC1 2.903 4.2782 2.4617 8.4716
MFE-280 GDSC1 3.1554 5.12 2.2806 8.8349
ESS-1 GDSC1 3.2671 5.3383 2.2677 8.513
MFE-296 GDSC1 3.7024 5.69 2.4381 5.7067
KLE GDSC1 3.8167 6.3659 2.19 7.2777
EN GDSC1 4.1712 7.0327 2.1178 6.8079
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-140 GDSC1 0.8826 8.6004 -1.5498 40.0752
BB65-RCC GDSC1 0.9397 10.7659 -2.5333 41.5901
786-O GDSC1 1.0715 3.5099 0.8122 29.7675
LB2241-RCC GDSC1 1.1035 8.3817 -1.2315 38.1825
RXF 393L GDSC1 1.7368 7.6652 -0.2797 31.7271
SN12C GDSC1 1.9813 4.8371 1.2817 21.6156
CAL-54 GDSC1 2.0181 6.3152 0.6365 25.643
LB1047-RCC GDSC1 2.3266 5.9942 1.0868 21.2857
TK-10 GDSC1 2.5858 6.2924 1.1861 19.4323
KMRC-20 GDSC1 2.6245 6.2931 1.2215 19.0156
OS-RC-2 GDSC1 2.6828 25.067 -8.0877 41.927
Caki-1 GDSC1 2.9091 6.2071 1.5224 15.6426
ACHN GDSC1 3.0559 15.5884 -3.0344 34.7537
SW156 GDSC1 3.1287 12.9893 -1.6737 31.0289
SW13 GDSC1 3.1534 4.9313 2.3728 8.1183
HA7-RCC GDSC1 3.4251 6.3704 1.8828 10.9419
A-704 GDSC1 3.4374 5.1834 2.4856 6.1888
NCC010 GDSC1 3.4386 5.5737 2.2917 7.7095
A-498 GDSC1 3.5194 7.2307 1.5296 13.2721
BFTC-909 GDSC1 3.526 9.3405 0.4809 20.2204
KTCTL-1M GDSC1 3.5976 13.3684 -1.4735 28.7984
NCC021 GDSC1 3.6555 5.6931 2.4015 6.1354
769-P GDSC1 3.669 8.5107 1.0108 16.392
VMRC-RCZ GDSC1 3.7065 7.321 1.6331 11.8646
KTCTL-195 GDSC1 3.7522 8.7296 0.9678 16.3885
VMRC-RCW GDSC1 3.7823 6.5702 2.0637 8.3555
KTCTL-13 GDSC1 3.8572 13.0614 -1.1092 26.6405
UO-31 GDSC1 4.3178 6.9482 2.2564 5.3987
KTCTL-26A GDSC1 5.3454 14.9429 -0.9006 21.4078
KMRC-1 GDSC1 5.3887 15.7859 -1.2827 22.8232
KTCTL-21 GDSC1 6.2326 9.0223 2.3793 1.5243
RCC10RGB GDSC1 7.8277 18.648 -0.9905 16.0604
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-81 GDSC1 -2.2709 14.1139 -7.2307 55.1971
CL-11 GDSC1 -1.3359 4.87 -2.2546 54.9974
C2BBe1 GDSC1 -0.2528 3.669 -0.6793 45.7131
HCC2998 GDSC1 -0.0616 3.6876 -0.4766 43.6656
SNU-C1 GDSC1 0 10.1444 -3.1397 46.547
MDST8 GDSC1 0.2205 7.6777 -1.7781 44.079
SW620 GDSC1 0.2427 5.3192 -0.7361 42.0072
RCM-1 [Human ESC] GDSC1 0.287 5.2213 -0.6499 41.4795
NCI-H716 GDSC1 0.3857 13.9459 -4.5992 45.8448
GP5d GDSC1 0.4496 6.9139 -1.2026 41.7301
SW1463 GDSC1 0.4528 6.0335 -0.8134 40.8001
LS411N GDSC1 0.4924 6.1883 -0.8392 40.615
SW1116 GDSC1 0.5152 6.0958 -0.7757 40.3028
LS513 GDSC1 0.5383 3.2399 0.3061 36.0957
LoVo GDSC1 0.5637 5.1301 -0.3207 38.583
COLO205 GDSC1 0.5658 6.7555 -1.0137 40.6016
HT-29 GDSC1 1.109 6.0393 -0.1415 34.5019
SK-CO-1 GDSC1 1.2469 3.2282 1.0823 26.9982
SNU-407 GDSC1 1.6272 8.0451 -0.5671 33.4253
KM12 GDSC1 1.6303 5.8137 0.4875 28.493
SW626 GDSC1 1.7521 7.4623 -0.1676 31.161
NCI-H508 GDSC1 2 11.4537 -1.8921 35.8412
NCI-H747 GDSC1 2.1374 5.5745 1.1025 22.0766
HCT 116 GDSC1 2.1936 5.1518 1.3544 20.0516
DiFi GDSC1 2.2332 5.7617 1.1079 21.5804
COLO 678 GDSC1 2.3198 13.9386 -2.843 36.7732
SNU-C5 GDSC1 2.44 6.4199 0.988 21.4302
SW48 GDSC1 2.7017 7.6432 0.6249 22.5916
RKO GDSC1 2.8747 7.7901 0.705 21.3776
SW1417 GDSC1 2.8815 9.3218 -0.0525 25.5738
LS180 GDSC1 3.1929 7.9617 0.8937 18.9104
SW837 GDSC1 3.1933 8.2348 0.7575 19.7815
HT115 GDSC1 3.4552 4.8326 2.6746 4.6429
LS1034 GDSC1 3.4707 8.5261 0.8427 18.1995
HCT 15 GDSC1 3.5504 6.4607 1.9387 10.0764
LS123 GDSC1 3.6413 6.3196 2.0802 8.6792
CaR-1 GDSC1 3.7381 7.0501 1.7923 10.5678
CCK-81 GDSC1 3.9204 6.9541 1.9773 8.5902
SNU-C2B GDSC1 4.3251 10.1416 0.7077 16.1719
CW-2 GDSC1 4.387 7.4346 2.0711 6.5833
SW948 GDSC1 4.5409 15.0523 -1.5609 26.1879
SNU-61 GDSC1 4.7065 10.8984 0.6164 15.5773
T84 GDSC1 5.0833 7.2607 2.5546 1.9346
COLO 320HSR GDSC1 6.7817 15.6311 -0.2434 14.9363
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 4.1339 12.7672 -0.7423 24.275
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-1 GDSC1 -1.7391 7.103 -3.5509 56.0699
Huh-7 GDSC1 2.3005 3.8668 2.0224 14.6737
JHH-6 GDSC1 2.3572 5.7241 1.2456 20.0471
SNU-387 GDSC1 2.7703 8.9934 0.0143 25.6908
HLE GDSC1 3.1748 12.5332 -1.4069 30.0104
JHH-2 GDSC1 3.2536 8.1741 0.8387 19.0344
HuH-1 GDSC1 3.3014 6.2627 1.8344 11.7611
JHH-4 GDSC1 3.3096 5.0909 2.4271 7.1011
JHH-7 GDSC1 3.5263 7.0726 1.614 12.6232
SK-HEP-1 GDSC1 3.5577 24.2034 -6.923 39.0737
Hep-G2/C3A GDSC1 3.6288 6.4288 2.0162 9.2151
SNU-449 GDSC1 3.7937 6.0517 2.3275 6.2874
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 173 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC15 GDSC1 -1.3142 6.9331 -3.0349 53.8695
NCI-H1666 GDSC1 -0.9077 5.164 -1.9015 51.7767
NCI-H1437 GDSC1 0.3441 5.3326 -0.6344 41.0437
NCI-H2291 GDSC1 0.4429 5.0783 -0.4278 39.7567
NCI-H2795 GDSC1 0.7431 3.0261 0.5825 33.2077
A-549 GDSC1 0.7649 4.8633 -0.0011 36.0114
NCI-H460 GDSC1 0.8042 8.8437 -1.7413 40.8675
LCLC-97TM1 GDSC1 0.8491 6.7623 -0.7297 38.1458
NCI-H727 GDSC1 0.99 21.0738 -7.5652 45.5211
NCI-H292 GDSC1 1.0277 7.7363 -1.001 37.9485
EBC-1 GDSC1 1.0996 3.6607 0.7963 29.6959
HCC44 GDSC1 1.1691 4.7045 0.4903 31.0726
KNS-62 GDSC1 1.2666 9.709 -1.7127 38.5664
SW1271 GDSC1 1.5018 6.826 -0.1086 32.1822
NCI-H358 GDSC1 1.6114 8.7949 -0.9443 34.829
NCI-H2087 GDSC1 1.7634 4.6721 1.1279 23.7989
NCI-H1915 GDSC1 1.7866 3.7827 1.5013 21.1052
SBC-5 GDSC1 1.7971 4.0768 1.4045 21.7201
SK-LU-1 GDSC1 1.8068 4.8192 1.11 23.691
A-427 GDSC1 1.8451 6.4903 0.3854 27.9465
NCI-H2009 GDSC1 1.8944 8.4543 -0.5131 31.9298
HOP-92 GDSC1 1.9234 7.7802 -0.1583 30.2817
NCI-H23 GDSC1 2.0136 6.1904 0.6913 25.3349
NCI-H1792 GDSC1 2.0989 5.2802 1.2009 21.5901
EPLC-272H GDSC1 2.1401 6.778 0.5317 25.6721
Calu-6 GDSC1 2.1472 7.1519 0.3574 26.6251
NCI-H1693 GDSC1 2.1614 14.984 -3.5024 38.4928
Lu-99A GDSC1 2.1737 4.0125 1.8303 16.7146
NCI-H1876 GDSC1 2.206 3.345 2.0977 14.6609
NCI-H2122 GDSC1 2.3202 3.5416 2.1617 13.5829
SK-MES-1 GDSC1 2.3353 4.3156 1.8735 15.5802
NCI-H290 GDSC1 2.3683 8.814 -0.2544 28.6815
RERF-LC-MS GDSC1 2.4 5.3144 1.4818 18.1571
NCI-H3122 GDSC1 2.4055 7.9671 0.1975 26.3034
NCI-H1944 GDSC1 2.4997 4.5878 1.9193 14.4448
NCI-H2170 GDSC1 2.5642 4.6092 1.9737 13.7332
NCI-H1355 GDSC1 2.6184 6.1817 1.2704 18.6977
HOP-62 GDSC1 2.6319 5.8551 1.4426 17.4002
NCI-H2085 GDSC1 2.6373 5.014 1.8545 14.3018
NCI-H1975 GDSC1 2.6479 5.406 1.676 15.6014
LXF 289 GDSC1 2.6775 6.386 1.2245 18.7656
NCI-H1048 GDSC1 2.758 3.829 2.5202 8.7148
COR-L23 GDSC1 2.7673 5.0843 1.9445 13.0423
NCI-H1581 GDSC1 2.7679 5.1249 1.9254 13.1867
COR-L105 GDSC1 2.7796 9.6404 -0.2999 27.1634
NCI-H2591 GDSC1 2.8177 8.1362 0.4827 22.9497
BEN GDSC1 2.8191 5.6177 1.732 14.443
EMC-BAC-2 GDSC1 2.8452 4.8856 2.1143 11.4
CAL-12T GDSC1 2.8643 7.1964 0.9912 19.5774
RERF-LC-KJ GDSC1 2.896 4.5422 2.3286 9.526
NCI-H2030 GDSC1 2.9107 4.4611 2.3816 9.0528
EMC-BAC-1 GDSC1 3.0125 6.8907 1.2735 17.031
NCI-H1573 GDSC1 3.1073 7.5528 1.0251 18.3737
NCI-H1734 GDSC1 3.1573 5.6408 2.0226 10.8456
HCC827 GDSC1 3.159 5.2627 2.2127 9.3534
NCI-H2373 GDSC1 3.1931 7.0117 1.3686 15.6448
DMS 273 GDSC1 3.2043 4.1223 2.82 4.4062
NCI-H647 GDSC1 3.215 5.5203 2.1324 9.7691
NCI-H1648 GDSC1 3.2606 5.4372 2.2128 8.9677
VMRC-LCD GDSC1 3.2793 4.152 2.8708 3.7152
NCI-H841 GDSC1 3.2842 5.1127 2.3949 7.448
NCI-H2810 GDSC1 3.2926 5.7244 2.0962 9.7633
NCI-H2228 GDSC1 3.3064 5.7707 2.0846 9.8036
NCI-H2369 GDSC1 3.3307 5.594 2.1932 8.8647
IST-SL2 GDSC1 3.334 5.8487 2.0686 9.8281
NCI-H1838 GDSC1 3.3533 4.5589 2.7294 4.5602
NCI-H2731 GDSC1 3.3538 6.2136 1.9026 11.0452
NCI-H1623 GDSC1 3.3663 14.9285 -2.4444 32.4085
NCI-H661 GDSC1 3.3931 5.9103 2.0865 9.4762
PC-14 GDSC1 3.4103 5.7952 2.1581 8.8553
ChaGo-K-1 GDSC1 3.4367 5.9197 2.1174 9.0809
LC-2/ad GDSC1 3.4401 6.2097 1.9753 10.1753
DMS 114 GDSC1 3.4706 4.9628 2.6219 5.0055
Calu-3 GDSC1 3.4744 5.4601 2.3771 6.9164
UMC-11 GDSC1 3.4767 6.3942 1.9128 10.5298
NCI-H3255 GDSC1 3.4795 5.7756 2.2238 8.101
NCI-H441 GDSC1 3.4945 7.9705 1.1399 16.1374
IST-SL1 GDSC1 3.5072 6.6275 1.8209 11.1285
NCI-H1563 GDSC1 3.5129 6.7653 1.7567 11.5975
NCI-H2722 GDSC1 3.526 4.6916 2.7989 3.4427
NCI-H1703 GDSC1 3.538 5.692 2.3118 7.2149
NCI-H2023 GDSC1 3.5435 5.6111 2.3564 6.8478
NCI-H2347 GDSC1 3.6142 8.9716 0.7368 18.3541
NCI-H838 GDSC1 3.6186 7.0477 1.7001 11.6603
PaCa-3 GDSC1 3.6199 6.9013 1.7741 11.0982
SBC-3 GDSC1 3.6355 5.6371 2.4141 6.0997
LOU-NH91 GDSC1 3.6445 5.5249 2.4764 5.5867
NCI-H211 GDSC1 3.6847 5.7579 2.3914 6.1233
NCI-H1869 GDSC1 3.6946 6.7549 1.9052 9.8515
NCI-H1299 GDSC1 3.7377 7.7232 1.4575 13.0479
SW1573 GDSC1 3.7462 8.7497 0.953 16.5067
NCI-H513 GDSC1 3.7575 6.068 2.2928 6.664
NCI-H1963 GDSC1 3.778 6.0116 2.3356 6.2715
NCI-H226 GDSC1 3.7803 9.1336 0.7887 17.4477
NCI-H596 GDSC1 3.8108 6.3212 2.2077 7.1592
NCI-H1770 GDSC1 3.8467 5.2185 2.7672 2.7995
NCI-H1694 GDSC1 3.8481 6.2345 2.2775 6.5109
NCI-H1781 GDSC1 3.8552 5.5111 2.6336 3.774
NCI-H2461 GDSC1 3.863 6.2883 2.2619 6.5866
RERF-LC-Sq1 GDSC1 3.874 15.1837 -2.1554 30.0552
NCI-H2405 GDSC1 3.8856 6.0461 2.3962 5.4928
NCI-H196 GDSC1 3.9147 7.0665 1.9178 9.0588
NCI-H2869 GDSC1 3.9249 7.0493 1.9338 8.9062
NCI-H1650 GDSC1 3.9256 5.4684 2.7004 3.0979
NCI-H1651 GDSC1 3.9313 6.0044 2.4483 4.9701
NCI-H1105 GDSC1 3.9772 5.9768 2.4929 4.5104
NCI-H1092 GDSC1 3.9851 8.1744 1.4238 12.481
NCI-H2595 GDSC1 3.9994 7.2776 1.8764 9.1139
COR-L279 GDSC1 4.049 5.8848 2.5839 3.6538
NCI-H2803 GDSC1 4.069 16.0725 -2.442 30.279
EKVX GDSC1 4.0712 11.59 -0.2055 22.027
NCI-H1755 GDSC1 4.0746 14.2775 -1.5419 27.5139
NCI-H187 GDSC1 4.0846 5.6366 2.7215 2.5821
NCI-H650 GDSC1 4.1008 6.8652 2.1499 6.7602
NCI-H2110 GDSC1 4.1291 8.4704 1.3855 12.3014
NCI-H524 GDSC1 4.1428 6.4618 2.3721 4.9844
NCI-H2141 GDSC1 4.201 5.8158 2.709 2.427
HARA [Human squamous cell lung carcinoma] GDSC1 4.2226 12.3854 -0.4829 22.8514
NCI-H847 GDSC1 4.2414 5.6506 2.8051 1.7146
ABC-1 GDSC1 4.2864 12.5675 -0.5238 22.836
COR-L321 GDSC1 4.2903 10.4345 0.5369 17.311
NCI-H345 GDSC1 4.3172 5.0924 3.067 0.2551
NCI-H64 GDSC1 4.354 7.9423 1.805 8.6212
NCI-H2227 GDSC1 4.39 7.8137 1.8917 7.89
NCI-H810 GDSC1 4.403 6.7038 2.4245 3.9852
DMS 79 GDSC1 4.4046 6.7354 2.4109 4.0783
SHP-77 GDSC1 4.4179 6.4063 2.569 2.9489
COR-L95 GDSC1 4.42 6.1624 2.6788 2.2146
NCI-H1793 GDSC1 4.4426 12.251 -0.2465 21.0498
NCI-H2029 GDSC1 4.4612 6.6141 2.5005 3.3305
NCI-H446 GDSC1 4.4632 6.6228 2.4977 3.3454
NCI-H69 GDSC1 4.5557 8.8372 1.5125 10.1607
NCI-H1436 GDSC1 4.6 6.5726 2.5976 2.4213
NCI-H1155 GDSC1 4.6409 14.1673 -1.0446 23.9717
NCI-H146 GDSC1 4.6691 8.1479 1.9181 6.9835
NCI-H2444 GDSC1 4.6745 13.5921 -0.7341 22.5857
LCLC-103H GDSC1 4.7141 12.7548 -0.2905 20.4438
NCI-H1688 GDSC1 4.789 6.4239 2.7561 1.2124
COLO 668 GDSC1 4.8025 7.4236 2.334 3.7809
DMS 53 GDSC1 4.8026 6.609 2.6868 1.5706
NCI-H1568 GDSC1 4.8936 7.2611 2.4565 2.8143
NCI-H720 GDSC1 4.9004 12.3914 0.0259 18.3135
NCI-H1341 GDSC1 4.9028 9.6826 1.343 10.3943
NCI-H209 GDSC1 4.9212 12.4296 0.0224 18.2719
HCC78 GDSC1 4.9299 8.8302 1.7648 7.4337
NCI-H526 GDSC1 4.9535 6.9519 2.6189 1.7486
LB647-SCLC GDSC1 4.9674 7.0921 2.5673 2.0243
NCI-H2172 GDSC1 5.0239 6.8713 2.6854 1.3038
NCI-H2804 GDSC1 5.0612 8.2656 2.1051 4.808
Lu-165 GDSC1 5.1508 6.4824 2.8872 0.3618
CPC-N GDSC1 5.1526 7.4734 2.5004 2.1474
COR-L88 GDSC1 5.2384 24.3947 -5.663 33.9084
Ms-1 GDSC1 5.2666 13.0916 -0.0524 17.6938
LC-1/sq GDSC1 5.2808 14.9988 -0.9753 21.8919
NCI-H1836 GDSC1 5.2994 6.8826 2.7997 0.5612
NCI-H1435 GDSC1 5.321 10.3945 1.2806 9.7585
NCI-H1304 GDSC1 5.3538 14.8125 -0.8305 21.0896
NCI-H82 GDSC1 5.3858 6.8052 2.861 0.3243
NCI-H2081 GDSC1 5.3974 15.443 -1.108 22.1172
NCI-H1993 GDSC1 5.4099 7.2458 2.7091 0.8247
NCI-H2818 GDSC1 5.4665 16.8543 -1.7508 24.3201
Lu-134-A GDSC1 5.5294 10.6841 1.2776 9.2868
Lu-135 GDSC1 5.5868 15.865 -1.1768 21.8942
NCI-H2135 GDSC1 5.6482 6.9632 2.901 0.1519
NCI-H835 GDSC1 5.8288 7.6889 2.7135 0.5339
LK-2 GDSC1 5.8541 7.302 2.8581 0.1747
SBC-1 GDSC1 5.8754 19.2591 -2.6317 26.08
NCI-H510A GDSC1 6.0994 14.7347 -0.2686 16.6308
Lu-65 GDSC1 6.1633 16.6517 -1.1491 20.3449
NCI-H322M GDSC1 6.2179 25.6188 -5.5146 31.6801
NCI-H520 GDSC1 6.4251 8.1496 2.7704 0.1864
NCI-H2342 GDSC1 6.4498 23.6091 -4.3476 29.019
Lu-139 GDSC1 6.7399 19.3505 -2.0535 22.3029
⏷ Show the Full List of 173 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 4.6463 9.4514 1.2784 11.5232
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-510 GDSC1 2.4668 11.0862 -1.294 32.27
TE-8 GDSC1 2.5485 5.1194 1.7185 15.7263
TE-15 GDSC1 2.62 11.7571 -1.494 32.3118
KYSE-520 GDSC1 2.94 6.3086 1.4994 15.6864
TE-5 GDSC1 2.9744 5.9517 1.7072 13.992
TE-4 GDSC1 2.9806 4.3442 2.5045 7.7996
KYSE-180 GDSC1 2.9808 4.7577 2.3031 9.3614
KYSE-140 GDSC1 2.9953 5.4759 1.9619 11.9546
KYSE-270 GDSC1 3.1414 5.6745 1.992 11.1451
OE33 GDSC1 3.2181 7.2355 1.278 16.1974
T.T GDSC1 3.2381 11.7305 -0.9524 28.1539
KYSE-410 GDSC1 3.3313 9.898 0.0417 23.3586
EC-GI-10 GDSC1 3.3619 6.1167 1.9577 10.59
KYSE-450 GDSC1 3.422 6.9869 1.5722 13.304
KYSE-70 GDSC1 3.4336 9.0701 0.5403 20.2068
OE21 GDSC1 3.4488 10.3188 -0.0713 23.503
TE-11 GDSC1 3.5258 9.7422 0.28 21.3673
TE-6 GDSC1 3.6216 6.1652 2.1417 8.2669
TE-9 GDSC1 3.7946 5.4506 2.6211 4.0315
OE19 GDSC1 3.892 5.5159 2.6559 3.5111
COLO 680N GDSC1 4.0154 7.6753 1.6927 10.4333
KYSE-150 GDSC1 4.114 7.6197 1.7921 9.4012
TE-10 GDSC1 4.2338 6.7733 2.2843 5.4042
TE-1 GDSC1 4.281 9.5487 0.9672 14.6676
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OV-90 GDSC1 -1.0254 2.5152 -1.229 53.6681
TYK-nu GDSC1 0.0804 4.7156 -0.6745 43.0288
OVCAR-5 GDSC1 0.7565 4.1292 0.2665 34.8251
OVK18 GDSC1 1.0234 11.6676 -2.893 41.758
A2780 GDSC1 1.2738 6.7542 -0.3005 34.2254
JHOS-2 GDSC1 1.6376 6.5957 0.1328 30.3321
EFO-27 GDSC1 1.8555 9.4976 -1.0594 34.0764
ES-2 GDSC1 2.0286 5.1987 1.1677 22.166
DOV13 GDSC1 2.6392 8.0187 0.3828 24.2736
TOV-21G GDSC1 2.7377 9.6783 -0.3553 27.5838
Caov-4 GDSC1 2.8804 6.42 1.3911 16.7219
OV56 GDSC1 2.9771 10.2639 -0.4405 27.0161
OVTOKO GDSC1 3.1946 9.4223 0.165 23.2248
OAW28 GDSC1 3.3241 4.6486 2.6604 5.2098
OVCAR-8 GDSC1 3.4084 8.4365 0.8363 18.4692
OVCAR-3 GDSC1 3.5166 6.0077 2.1376 8.6488
OAW42 GDSC1 3.5456 10.604 -0.1344 23.4694
TOV-112D GDSC1 3.5487 10.1307 0.1047 22.2353
OVCAR-4 GDSC1 3.5664 12.086 -0.8581 26.63
SK-OV-3 GDSC1 3.5771 5.6993 2.3386 6.8763
OC 314 GDSC1 3.7137 6.2906 2.1501 7.9054
EFO-21 GDSC1 3.84 6.9188 1.9349 9.1599
OVISE GDSC1 4.0453 14.9354 -1.8935 28.7522
Kuramochi GDSC1 4.4336 9.1061 1.2958 12.011
OVKATE GDSC1 4.4544 7.3419 2.1592 5.7727
JHOS-4 GDSC1 4.8866 6.7042 2.6884 1.4528
IGROV-1 GDSC1 5.0384 10.1975 1.188 11.0701
RMG-I GDSC1 5.0707 9.4603 1.5591 8.5098
FU-OV-1 GDSC1 5.2736 17.1679 -2.0495 25.8095
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Panc 02.03 GDSC1 -0.9675 4.5103 -1.7303 52.4056
PSN1 GDSC1 0.0013 2.8711 -0.1896 42.2969
HuP-T4 GDSC1 0.1071 8.8155 -2.4132 45.4405
SUIT-2 GDSC1 0.7693 6.6897 -0.7776 38.7558
MIA PaCa-2 GDSC1 0.9887 5.2532 0.0752 34.2661
SU.86.86 GDSC1 1.0674 5.6724 -0.0225 34.2325
Hs 766T GDSC1 1.2261 12.3386 -3.0334 41.1391
HPAC GDSC1 1.3471 23.0519 -8.2335 44.9604
HuP-T3 GDSC1 1.5723 10.1876 -1.6594 37.0555
PaTu 8902 GDSC1 1.609 6.8052 0.0063 31.0923
Panc 03.27 GDSC1 1.709 6.2907 0.3457 28.8598
Panc 10.05 GDSC1 1.7571 5.3129 0.8418 25.7035
KP-2 GDSC1 1.8968 7.2298 0.0824 29.2696
HPAF-II GDSC1 1.9698 4.3522 1.4775 20.2951
AsPC-1 GDSC1 2.1462 7.3469 0.2617 27.1483
Panc 04.03 GDSC1 2.2329 11.1516 -1.5338 33.9379
KP-4 GDSC1 2.6022 3.661 2.4235 10.2163
PaTu 8988t GDSC1 2.6686 5.29 1.7517 14.9408
KP-3 GDSC1 2.8177 5.685 1.6977 14.709
BxPC-3 GDSC1 2.9627 5.4227 1.959 12.1094
Capan-1 GDSC1 2.9881 6.544 1.4249 16.0394
SW1990 GDSC1 3.0349 5.9513 1.761 13.3411
PL4 GDSC1 3.0388 6.1393 1.6709 14.0101
DAN-G GDSC1 3.0922 5.2395 2.1656 9.983
Capan-2 GDSC1 3.3593 10.5116 -0.2418 24.6643
MZ-PC-1 GDSC1 3.787 6.5963 2.0543 8.413
KP-1N GDSC1 3.9346 9.4987 0.7281 17.3047
Panc 08.13 GDSC1 4.0127 7.8841 1.5879 11.2106
QGP-1 GDSC1 4.1309 10.0801 0.5911 17.4964
CFPAC-1 GDSC1 4.1478 11.0117 0.1418 19.9956
YAPC GDSC1 4.4992 7.9055 1.9214 7.3869
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1 2.7928 11.6907 -1.3112 31.0742
NCI-H2452 GDSC1 3.1577 5.2348 2.2255 9.2581
MPP 89 GDSC1 3.2409 7.1153 1.3573 15.5449
NCI-H28 GDSC1 3.4053 8.1188 0.9926 17.4584
IST-Mes1 GDSC1 4.1788 7.6514 1.8231 8.9829
NCI-H2052 GDSC1 4.404 10.3993 0.6395 16.3436
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU145 GDSC1 3.0327 3.9205 2.7572 5.6253
PC-3 GDSC1 3.936 5.8448 2.5283 4.3527
LNCaP clone FGC GDSC1 4.2141 6.6794 2.3158 5.221
22Rv1 GDSC1 4.2307 7.051 2.1496 6.4113
VCaP GDSC1 5.7443 7.0716 2.8978 0.1357
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 3.5632 5.2125 2.5694 5.1161
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-mel GDSC1 -3.4148 0.4628 -3.4908 75.9101
MMAc-SF GDSC1 -2.8244 2.848 -3.2625 66.8639
IGR-37 GDSC1 -2.3489 0.5733 -2.3858 68.4569
SK-MEL-28 GDSC1 -2.3174 3.074 -2.7665 63.5015
CP50-MEL-B GDSC1 -2.2369 5.1782 -3.3365 60.2315
M14 GDSC1 -2.2352 1.4121 -2.348 65.8933
LOX-IMVI GDSC1 -2.2207 6.0528 -3.643 59.2776
WT2-iPS GDSC1 -2.2015 0.8945 -2.2564 66.5869
CP66-MEL GDSC1 -2.1619 10.2699 -5.3564 56.2647
451Lu GDSC1 -1.9324 1.4686 -2.0329 63.2851
Mel Ho GDSC1 -1.7625 3.1348 -2.1769 59.5991
COLO 679 GDSC1 -1.484 3.4045 -1.9457 57.1724
A101D GDSC1 -1.2899 7.8316 -3.3902 53.4189
A-375 GDSC1 -1.2883 1.5317 -1.3571 56.9592
SH-4 GDSC1 -0.9697 2.6278 -1.192 53.0596
WM115 GDSC1 -0.9105 2.9927 -1.2115 52.3514
HT-144 GDSC1 -0.7052 3.0385 -0.999 50.2801
SK-MEL-1 GDSC1 -0.6849 5.8985 -1.9495 50.0497
IPC-298 GDSC1 -0.624 3.0532 -0.9141 49.4376
LB2518-MEL GDSC1 -0.5594 5.3078 -1.5836 49.0586
UACC-257 GDSC1 -0.2516 4.9873 -1.1323 46.3529
SK-MEL-5 GDSC1 -0.1427 7.5561 -2.0916 46.5523
RVH-421 GDSC1 0.0017 9.0446 -2.6239 46.1748
SK-MEL-2 GDSC1 0.0181 4.1258 -0.5313 43.1605
Hs 938.T GDSC1 0.0609 11.7858 -3.8613 46.6959
HMV-II GDSC1 0.3016 4.6312 -0.4058 40.6771
MZ-MEL-2 GDSC1 0.4627 5.3099 -0.5001 39.8494
WM35 GDSC1 0.463 4.6341 -0.234 38.959
COLO 829 GDSC1 0.5855 4.4964 -0.051 37.4101
MeWo GDSC1 0.8755 4.9273 0.0904 34.8979
G-361 GDSC1 1.1001 6.1881 -0.2171 34.867
COLO 783 GDSC1 1.1339 5.1121 0.2859 32.3696
WM278 GDSC1 1.1739 9.0373 -1.4769 38.4515
GAK GDSC1 1.2843 2.6532 1.2387 25.7596
SK-MEL-3 GDSC1 1.3897 10.9891 -2.2208 39.0962
CHL-1 GDSC1 1.4013 8.5025 -1.0026 36.0328
SK-MEL-30 GDSC1 1.4209 5.2201 0.5382 29.3504
COLO 792 GDSC1 1.429 5.0297 0.6282 28.7847
SK-MEL-24 GDSC1 1.6706 6.4491 0.2339 29.6488
A2058 GDSC1 2.2543 6.615 0.7186 24.0124
WM793 GDSC1 2.3372 6.104 1.0441 21.5253
Mel JuSo GDSC1 2.358 7.6134 0.328 25.814
RPMI-7951 GDSC1 2.3912 7.0572 0.6314 23.9144
A-431 GDSC1 2.5195 5.6709 1.4263 18.0157
DJM-1 GDSC1 3.0526 7.4344 1.0371 18.5082
IST-MEL1 GDSC1 3.0748 5.7203 1.9111 12.0315
UACC-62 GDSC1 3.1233 3.8511 2.8779 4.2946
A-388 GDSC1 3.687 6.8865 1.834 10.419
COLO 800 GDSC1 3.8109 5.5404 2.589 4.2313
WM1552C GDSC1 3.9006 9.0281 0.9356 16.0966
SK-MEL-31 GDSC1 3.9139 6.9257 1.9864 8.5405
LB373-MEL-D GDSC1 4.1541 15.0368 -1.8573 28.3115
VMRC-MELG GDSC1 4.2668 6.8821 2.2543 5.5419
IGR-1 GDSC1 4.4332 8.3572 1.6595 9.456
MZ-MEL-7 GDSC1 5.1329 7.2788 2.5714 1.7752
EquiPSC Line K2 GDSC1 -0.1002 7.0895 -1.8419 46.0706
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 2.5122 4.834 1.8177 15.1483
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RKN GDSC1 0.1542 9.4716 -2.6725 45.4394
Hs 633.T GDSC1 0.3899 5.675 -0.7271 40.9847
SW872 GDSC1 0.6908 5.457 -0.3215 37.7564
RD GDSC1 0.9912 10.3173 -2.2675 40.9305
HT-1080 GDSC1 1.5808 4.0191 1.1944 24.3394
SW982 GDSC1 1.774 9.003 -0.8931 33.8938
SK-LMS-1 GDSC1 1.83 5.036 1.0392 24.0432
MFH-ino GDSC1 1.9686 8.0879 -0.2652 30.5437
GCT GDSC1 2.2335 12.6455 -2.2753 35.864
SK-UT-1 GDSC1 2.4789 5.6191 1.4126 18.2983
VA-ES-BJ GDSC1 2.7662 6.4995 1.2492 18.2132
G-401 GDSC1 3.0657 4.948 2.2866 9.1416
KYM-1 GDSC1 3.0847 4.5793 2.486 7.5048
A-204 GDSC1 3.1075 5.3113 2.1433 10.0967
STS-0421 GDSC1 3.7068 5.5417 2.5142 5.1041
SW684 GDSC1 4.1323 6.6927 2.2547 5.8874
MES-SA GDSC1 4.1765 5.6265 2.7798 1.9969
Rh41 GDSC1 4.2153 7.7751 1.7888 9.1305
EW-8 GDSC1 4.4243 6.6083 2.4812 3.5406
Rh18 GDSC1 5.4574 12.7752 0.235 15.674
G-402 GDSC1 5.4833 9.4524 1.8156 5.8819
Rh30 GDSC1 5.491 7.1224 2.7876 0.4868
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCUM-1 GDSC1 -1.9107 1.3687 -1.9977 63.2457
AGS GDSC1 -1.108 5.3372 -2.1811 53.1815
TMK-1 GDSC1 0.8311 11.3808 -2.9338 42.6181
NUGC-3 GDSC1 2.3937 7.8395 0.2495 26.0796
RERF-GC-1B GDSC1 2.5249 5.1897 1.6623 16.2533
TGBC11TKB GDSC1 2.5935 7.9261 0.3878 24.4418
NUGC-4 GDSC1 2.8048 7.0561 1.0082 19.7107
MKN45 GDSC1 2.8517 4.7619 2.1804 10.8625
SNU-1 GDSC1 3.0534 12.4706 -1.4781 30.6737
MKN28 GDSC1 3.1511 6.3513 1.6626 13.6343
Fu97 GDSC1 3.1686 9.5918 0.0583 23.8864
KATO III GDSC1 3.268 5.8461 2.0146 10.4907
SNU-5 GDSC1 3.3468 17.0185 -3.5057 34.8393
GCIY GDSC1 3.3773 9.2412 0.4084 21.1863
23132/87 GDSC1 3.4089 6.419 1.8452 11.2885
Hs 746.T GDSC1 3.5481 7.8648 1.2362 15.2785
MKN7 GDSC1 3.6419 7.8711 1.3082 14.4435
HGC-27 GDSC1 3.7786 5.1413 2.759 3.0328
SK-GT-2 GDSC1 3.7819 6.7368 1.981 8.9907
MKN1 GDSC1 3.8921 7.5793 1.6478 11.1507
HSC-39 GDSC1 3.9193 6.7473 2.078 7.8274
IM95 GDSC1 3.9612 17.5318 -3.2576 32.5857
SNU-16 GDSC1 4.3743 13.2344 -0.7869 23.7135
RF-48 GDSC1 4.4573 14.1343 -1.1696 25.0031
NCI-N87 GDSC1 4.5698 24.2906 -6.1415 35.9977
SCH GDSC1 4.7792 6.5622 2.6947 1.5577
ECC10 GDSC1 5.3425 23.7633 -5.2676 33.0633
SNG-M GDSC1 5.797 16.0793 -1.1302 21.1726
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BHT-101 GDSC1 -1.7128 1.3638 -1.7876 61.4192
K5 GDSC1 -1.4777 -0.2256 -1.4779 59.9705
TT2609-C02 GDSC1 -1.0926 2.9426 -1.3978 54.121
HTC-C3 GDSC1 -0.7635 2.9548 -1.042 50.8841
KMH-2 GDSC1 -0.6377 2.6263 -0.8312 49.5594
IHH-4 GDSC1 0.4925 3.2657 0.2493 36.7004
ASH-3 GDSC1 1.1256 7.717 -0.8958 37.1168
CAL-62 GDSC1 1.456 5.4124 0.4904 29.4245
ML-1 [Human leukemia] GDSC1 1.6014 7.3496 -0.2587 32.3181
8505C GDSC1 1.6119 8.0027 -0.5612 33.4784
B-CPAP GDSC1 2.3011 4.4655 1.7729 16.4892
8305C GDSC1 2.518 12.418 -1.9123 33.9025
CGTH-W-1 GDSC1 2.609 9.646 -0.4523 28.5361
WRO GDSC1 3.4626 9.2784 0.4601 20.573
TT GDSC1 3.6063 6.1365 2.1441 8.2984
FTC-133 GDSC1 4.1201 11.4806 -0.1128 21.4084
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-4 GDSC1 -2.453 5.4382 -3.6629 61.0513
NCI-H3118 GDSC1 -1.188 6.1239 -2.5721 53.4229
JHU-011 GDSC1 -0.1179 7.0175 -1.8286 46.168
BICR 78 GDSC1 0.0284 6.4218 -1.4196 44.751
DOK GDSC1 0.0695 12.1574 -4.0313 46.7492
CAL-27 GDSC1 0.1667 7.4132 -1.7133 44.303
PCI-04B GDSC1 0.6033 6.4376 -0.8343 39.9127
HO-1-N-1 GDSC1 0.6916 3.6171 0.3656 34.7483
PE/CA-PJ15 GDSC1 0.7921 5.5789 -0.2673 36.9151
BICR 22 GDSC1 0.9742 5.1705 0.0946 34.2646
CAL-33 GDSC1 1.0271 8.5375 -1.3796 38.9464
JHU-022 GDSC1 1.3612 9.7009 -1.6195 37.9101
Ca9-22 GDSC1 1.4179 6.2789 0.062 31.8487
HSC-3 GDSC1 1.5227 8.6292 -0.9481 35.2674
UPCI-SCC-090 GDSC1 1.8494 6.1702 0.5403 27.0518
PCI-06A GDSC1 2.0246 9.0794 -0.6984 32.0496
FaDu GDSC1 2.0843 5.5915 1.0422 22.7419
PCI-38 GDSC1 2.1236 7.537 0.148 27.8496
JHU-029 GDSC1 2.1382 6.9238 0.4594 26.0975
BB30-HNC GDSC1 2.4925 6.5256 0.9854 21.2117
HO-1-u-1 GDSC1 2.5806 5.3714 1.6288 16.2524
SKN-3 GDSC1 2.5934 21.6581 -6.4602 40.8403
KON GDSC1 2.6955 5.0613 1.8875 13.7919
SCC-25 GDSC1 2.7214 7.5706 0.6785 22.1812
KOSC-2 GDSC1 2.8781 6.1998 1.4982 15.9485
OSC-20 GDSC1 3.0231 9.628 -0.0834 25.166
BHY GDSC1 3.308 6.3537 1.7945 12.0426
SAS GDSC1 3.3824 8.7764 0.6449 19.7651
Detroit 562 GDSC1 3.3882 6.6457 1.7149 12.3561
BB49-HNC GDSC1 3.3957 12.5386 -1.2251 28.6124
SCC-4 GDSC1 3.4296 7.5691 1.2874 15.3438
SCC-15 GDSC1 3.5195 5.9109 2.1882 8.2439
HSC-2 GDSC1 3.5792 9.0945 0.6471 19.0336
BICR 10 GDSC1 3.6108 7.2197 1.6082 12.3738
SAT [Human HNSCC] GDSC1 3.9067 21.0493 -5.0593 35.9985
SCC-9 GDSC1 4.094 6.1246 2.5 4.1606
LB771-HNC GDSC1 4.5799 37.382 -12.6714 41.3351
PCI-15A GDSC1 4.876 6.7446 2.6667 1.5852
OSC-19 GDSC1 4.914 6.4008 2.8215 0.7685
PCI-30 GDSC1 7.3992 20.91 -2.3498 21.8534
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RT-112 GDSC1 -0.119 10.7475 -3.5406 47.3211
639V GDSC1 1.3251 8.7681 -1.203 36.9967
KU-19-19 GDSC1 1.6098 5.1943 0.7439 27.096
BFTC-905 GDSC1 1.6485 3.1918 1.5295 21.6925
T24 GDSC1 1.67 11.0492 -1.992 37.4292
SW780 GDSC1 1.6887 5.6196 0.6344 27.3338
CAL-29 GDSC1 2.2569 9.2097 -0.5507 30.4414
SW1710 GDSC1 2.4472 5.8091 1.2909 19.3141
UM-UC-3 GDSC1 2.5523 7.7989 0.4136 24.4743
J82 GDSC1 3.2885 7.9371 0.9864 17.9352
5637 GDSC1 3.3589 4.5128 2.757 4.3234
TCCSUP GDSC1 3.3707 8.3164 0.8652 18.4227
647V GDSC1 3.9772 10.6597 0.1838 20.3297
HT-1376 GDSC1 4.4326 8.2429 1.7143 9.0633
RT-4 GDSC1 4.5918 6.6981 2.5378 2.8241
HT-1197 GDSC1 5.2378 12.3278 0.2985 15.9105
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BPH-1 GDSC1 0.3129 4.8264 -0.4676 40.7844
CAL-39 GDSC1 1.1813 5.0479 0.3624 31.6925
HEY GDSC1 1.3571 4.263 0.8632 27.7625
OVMIU GDSC1 1.3983 6.6908 -0.1476 32.908
NEC8 GDSC1 2.3483 3.3624 2.2481 12.8306
ACC-OV7 GDSC1 2.462 10.2234 -0.8693 30.8132
TC-YIK GDSC1 2.5347 6.7296 0.9245 21.4263
PA-1 GDSC1 2.5992 4.2701 2.1636 12.1403
NT2-D1 GDSC1 2.6054 3.9667 2.303 11.075
SKN GDSC1 2.6469 10.3847 -0.7866 29.751
ME-180 GDSC1 2.6901 7.8502 0.5118 23.3151
C-4-I GDSC1 2.7911 8.2459 0.4047 23.5098
JHOS-3 GDSC1 2.9249 6.7035 1.2899 17.2677
KGN GDSC1 2.9635 6.7418 1.3049 17.0041
OVCA433 GDSC1 2.9922 10.5746 -0.5827 27.5738
PWR-1E GDSC1 2.9945 4.5981 2.394 8.5973
OVCA420 GDSC1 3.0147 5.6045 1.9155 12.2354
SW954 GDSC1 3.0461 9.596 -0.0478 24.8995
C-33 A GDSC1 3.2577 4.9712 2.4431 7.1668
SW756 GDSC1 3.2661 6.0564 1.9079 11.3252
PEO1 GDSC1 3.2771 4.8623 2.5141 6.5354
LB831-BLC GDSC1 3.3611 4.9609 2.5349 6.0669
JEG-3 GDSC1 3.4762 5.5787 2.3194 7.3632
HT-3 GDSC1 3.6098 7.2495 1.5926 12.4931
DoTc2 4510 GDSC1 3.6409 9.9573 0.2661 21.0334
SiHa GDSC1 3.6416 5.1659 2.6509 4.2406
OV17R GDSC1 3.6502 5.5909 2.448 5.7898
SW962 GDSC1 3.7359 14.1184 -1.7353 29.2112
DSH1 GDSC1 3.9976 7.0118 2.0053 8.1473
UWB1.289 GDSC1 4.407 8.4196 1.611 9.8766
SKG-IIIa GDSC1 4.6347 8.2441 1.8501 7.5546
Ca Ski GDSC1 4.8301 9.8746 1.2014 11.5342
HEC-1 GDSC1 5.4347 7.281 2.7061 0.8173
JAR GDSC1 5.6828 7.3916 2.7644 0.4561
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug

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