Details of the Drug

General Information of Drug (ID: DMF57DM)

Drug Name
Pazopanib
Synonyms
Pazopanib; Pazopanib (GW-786034); 444731-52-6; 5-((4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide; 5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide; 5-[[4-[(2,3-dimethylindazol-6-yl)-methyl-amino]pyrimidin-2-yl]amino]-2-methyl-benzenesulfonamide; 790713-33-6; 7RN5DR86CK; CHEBI:71219; DSSTox_CID_28659; DSSTox_GSID_48733; DSSTox_RID_82929; GW 78603; GW 786034; GW-786034; GW786034; MFCD11616589; NCGC00188865-01; UNII-7RN5DR86CK
Affected Organisms
Humans and other mammals
ATC Code
L01EX03: Pazopanib
L01EX: Other protein kinase inhibitors
L01E: PROTEIN KINASE INHIBITORS
L01: ANTINEOPLASTIC AGENTS
L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 437.5
Logarithm of the Partition Coefficient (xlogp) 3.1
Rotatable Bond Count (rotbonds) 5
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 8
ADMET Property
BDDCS Class
Biopharmaceutics Drug Disposition Classification System (BDDCS) Class 2: low solubility and high permeability [1]
Clearance
The drug present in the plasma can be removed from the body at the rate of 0.06 mL/min/kg [2]
Half-life
The concentration or amount of drug in body reduced by one-half in 35 hours [2]
Metabolism
The drug is metabolized via the CYP3A4 and to a lesser extent by CYP1A2 and CYP2C8 []
Unbound Fraction
The unbound fraction of drug in plasma is 0.01% [2]
Vd
The volume of distribution (Vd) of drug is 11.1 L []
Adverse Drug Reaction (ADR)
ADR Term Variation Related DOT DOT ID REF
Hemorrhage rs3064744 UGT1A1 OTH1C8OJ [3]
Hepatotoxicty rs2395029 HCP5 OTV0YRI8 [4]
Chemical Identifiers
Formula
C21H23N7O2S
IUPAC Name
5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide
Canonical SMILES
CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N
InChI
CUIHSIWYWATEQL-UHFFFAOYSA-N
InChIKey
1S/C21H23N7O2S/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25)
Cross-matching ID
PubChem CID
10113978
ChEBI ID
CHEBI:71219
CAS Number
444731-52-6
UNII
7RN5DR86CK
DrugBank ID
DB06589
INTEDE ID
DR1248
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4)
Main DME 		DE4LYSA CP3A4_HUMAN Substrate [5]
Cytochrome P450 2D6 (CYP2D6) DECB0K3 CP2D6_HUMAN Substrate [6]
Cytochrome P450 1A2 (CYP1A2) DEJGDUW CP1A2_HUMAN Substrate [5]
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Substrate [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Gene/Protein Processing [7]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Gene/Protein Processing [8]
Cytochrome P450 1B1 (CYP1B1) OTYXFLSD CP1B1_HUMAN Gene/Protein Processing [8]
Cytochrome P450 2B6 (CYP2B6) OTOYO4S7 CP2B6_HUMAN Gene/Protein Processing [9]
Cytochrome P450 2C8 (CYP2C8) OTHCWT42 CP2C8_HUMAN Gene/Protein Processing [9]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Gene/Protein Processing [9]
HLA class I histocompatibility antigen protein P5 (HCP5) OTV0YRI8 HCP5_HUMAN Drug Response [4]
Interleukin-1 beta (IL1B) OT0DWXXB IL1B_HUMAN Protein Interaction/Cellular Processes [10]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Post-Translational Modifications [11]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Post-Translational Modifications [11]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 5.156 15.1233 -1.3722 21.6728
NOS-1 [Human HNSCC] GDSC1 -0.6364 2.6832 -0.8867 46.0609
NY GDSC1 0.9372 4.0354 0.4006 29.1968
H-EMC-SS GDSC1 2.2958 8.917 -0.5641 27.5621
CAL-72 GDSC1 2.375 11.1503 -1.6071 31.3492
ES6 GDSC1 2.3898 5.9881 0.9713 18.1323
SK-N-MC CTRP2 2.4332 4.6095 2.3828 24.2284
CHSA8926 GDSC1 2.7753 15.0491 -3.2128 34.315
G-292 clone A141B1 GDSC1; CTRP2 3.0601 6.4753 2.6605 21.2938
CAL-78 GDSC1; CTRP2 3.2252 8.2102 2.1913 22.5448
HuO-3N1 GDSC1 3.5727 8.7506 0.5869 16.2908
ES4 GDSC1 3.6016 5.576 2.1724 4.6427
EW-13 GDSC1 3.6611 7.1763 1.4339 10.0652
TC71 CTRP2 3.6682 6.4395 3.3335 17.0189
CHSA0108 GDSC1 3.7071 6.9271 1.59 8.7585
MHH-ES-1 GDSC1; CTRP2 3.8458 6.9174 3.3606 16.4021
SK-ES-1 GDSC1; CTRP2 3.9198 6.7772 3.4912 15.6987
EW-16 GDSC1 4.0124 7.497 1.5291 8.3392
ES1 GDSC1 4.0267 9.3567 0.6314 14.5494
ES8 GDSC1 4.037 6.3527 2.0889 4.1815
A-673 GDSC1; CTRP2 4.0718 5.8271 3.9469 13.5739
EW-24 GDSC1 4.18 6.0159 2.3248 2.277
ES5 GDSC1 4.382 7.7372 1.6602 6.4434
ES7 GDSC1 4.5291 15.6295 -2.0901 26.0198
CHSA0011 GDSC1 4.5292 7.944 1.6564 6.1277
EW-1 GDSC1 4.7227 7.5589 1.9457 3.7619
EW-11 GDSC1 4.8112 9.9642 0.8871 10.6896
TC-71 GDSC1 4.8531 11.2935 0.2776 14.366
SK-PN-DW GDSC1 4.879 6.707 2.3809 1.0337
U2OS GDSC1; CTRP2 4.8921 12.7522 1.6877 20.175
EW-3 GDSC1 5.1475 7.3219 2.2591 1.337
HuO9 GDSC1 5.1727 8.0267 1.9831 2.7871
EW-7 GDSC1 5.2611 6.9651 2.4417 0.5113
HOS GDSC1; CTRP2 5.2783 10.332 3.2329 13.3531
SW1353 CTRP2 5.3643 11.6245 2.6691 15.4337
EW-18 GDSC1 5.395 9.0218 1.673 4.306
SaOS-2 GDSC1; CTRP2 5.6904 10.3017 3.614 10.9074
SJSA-1 GDSC1; CTRP2 5.7124 10.5042 3.5321 11.2016
Hs 888.T CTRP2 5.853 17.3717 0.2205 22.8428
MG-63 GDSC1; CTRP2 6.9639 17.2773 1.1746 17.7294
Hs 822.T CTRP2 7.1335 8.0214 5.7509 0.1759
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 210 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 2.3487 5.0708 2.2292 25.0279
MEC1 CTRP2 4.286 6.2044 4.0795 12.4432
JM1 GDSC1; CTRP2 3.8267 6.0498 3.6227 15.4881
EoL-1 GDSC1; CTRP2 -9.8269 -6.5496 -9.827 95.5724
Kasumi-1 CTRP2 -2.8558 2.8448 -3.0185 58.278
KG-1 GDSC1 -0.3726 2.1262 -0.4841 42.6308
MY-M12 GDSC1 0.1849 4.0652 -0.4171 38.1283
Pfeiffer CTRP2 0.5434 3.4598 0.502 36.7808
KMS-26 CTRP2 0.9132 2.552 0.9116 34.1902
MOLM-13 GDSC1; CTRP2 1.1371 4.7574 0.9774 33.2142
GDM-1 GDSC1; CTRP2 1.2948 6.8853 0.6092 33.7815
MV4-11 GDSC1; CTRP2 1.4833 4.973 1.313 30.9546
NCO2 CTRP2 1.6956 3.9422 1.667 29.0681
GA-10 CTRP2 1.7113 3.7196 1.6955 28.9205
EB1 CTRP2 1.7321 4.8686 1.5993 29.1762
EB2 GDSC1 1.7774 4.3301 1.1621 19.5889
Peer CTRP2 1.9465 3.9295 1.9274 27.3647
KMS-21-BM CTRP2 2.0092 4.2533 1.9706 27.0127
ALL-SIL GDSC1; CTRP2 2.0595 4.7712 1.9655 26.866
Ku812 GDSC1; CTRP2 2.0596 5.052 1.9209 27.0184
LP-1 GDSC1; CTRP2 2.1604 4.2774 2.1268 25.9885
KMS-11 CTRP2 2.1955 7.8384 1.2469 28.8717
Daudi GDSC1; CTRP2 2.2531 4.9725 2.1426 25.6334
Karpas-231 GDSC1 2.2608 6.8477 0.4301 22.3209
CML-T1 CTRP2 2.3125 4.7545 2.2377 25.1152
SKM-1 CTRP2 2.3669 4.4954 2.3244 24.6431
MOLT-3 CTRP2 2.5366 4.7107 2.4811 23.5566
SU-DHL-6 GDSC1; CTRP2 2.545 5.6095 2.3348 24.0377
CTV-1 GDSC1 2.5472 7.0089 0.6067 19.9716
WSU-DLCL2 GDSC1; CTRP2 2.5671 5.0182 2.4725 23.4877
SU-DHL-10 CTRP2 2.617 3.2663 2.617 22.8338
Ri-1 CTRP2 2.6205 5.4128 2.4593 23.3635
SU-DHL-4 GDSC1; CTRP2 2.6365 4.5751 2.6002 22.8259
RPMI-8402 GDSC1; CTRP2 2.6641 4.483 2.6367 22.6119
P30/OHK GDSC1 2.7118 5.8686 1.319 14.2563
LAMA-84 GDSC1; CTRP2 2.7454 4.9041 2.6793 22.2021
KMS-34 CTRP2 2.7932 5.1297 2.6976 21.9856
697 GDSC1; CTRP2 2.7932 4.8824 2.733 21.8636
RS4;11 GDSC1; CTRP2 2.8641 5.9038 2.6111 22.067
NALM-6 GDSC1; CTRP2 2.8731 4.7417 2.8332 21.2622
WIL2 NS GDSC1 2.9054 4.7092 2.0653 7.7205
U-698-M GDSC1 2.9204 7.6021 0.6323 18.324
JURL-MK1 GDSC1; CTRP2 2.9412 5.155 2.8526 20.9758
MEG-01 GDSC1 2.9573 4.8012 2.0636 7.5407
SU-DHL-16 GDSC1 2.9706 5.6148 1.668 10.5918
P32/ISH GDSC1 2.985 6.3499 1.3126 13.2584
KM-H2 GDSC1; CTRP2 2.9873 5.2107 2.8932 20.6876
EM-2 GDSC1; CTRP2 3.0587 4.6995 3.0318 19.9813
SU-DHL-8 GDSC1; CTRP2 3.0958 7.5131 2.3331 22.391
Jurkat CTRP2 3.1382 4.7197 3.1132 19.4455
Hs 611.T CTRP2 3.1444 6.1618 2.8467 20.3641
KHM-1B CTRP2 3.15 5.1325 3.0798 19.5214
SUP-T1 GDSC1; CTRP2 3.1505 6.4146 2.7779 20.5954
KYO-1 CTRP2 3.1544 5.5746 3.0052 19.7674
NU-DUL-1 GDSC1; CTRP2 3.1733 4.5434 2.9367 7.9951
CA46 GDSC1; CTRP2 3.2451 7.324 2.5646 21.1055
QIMR-WIL GDSC1 3.2549 6.7978 1.3092 12.32
OCI-Ly3 CTRP2 3.2621 6.7026 2.8057 20.1625
RPMI-6666 GDSC1; CTRP2 3.2861 11.1485 0.9421 26.676
VAL GDSC1 3.2902 7.5922 0.941 14.8654
JVM-3 GDSC1; CTRP2 3.3323 6.3483 2.9964 19.2544
OPM-2 GDSC1; CTRP2 3.3336 4.8338 3.3083 18.1451
BC-1 GDSC1 3.3418 8.094 0.732 16.1217
KMS-12-BM GDSC1; CTRP2 3.377 5.5805 3.2457 18.2221
OCI-AML-2 GDSC1; CTRP2 3.392 5.6807 3.2403 18.1942
Hs 445 GDSC1 3.4062 5.2105 2.2123 4.8863
HDLM-2 GDSC1; CTRP2 3.4068 6.6912 2.9665 19.1439
MOLM-16 CTRP2 3.4148 5.9157 3.2088 18.2357
SUP-M2 GDSC1; CTRP2 3.4443 5.6287 3.3086 17.7894
NU-DHL-1 CTRP2 3.445 5.29 3.3723 17.5649
KMS-20 CTRP2 3.4589 4.9346 3.4309 17.3194
KE-37 GDSC1; CTRP2 3.4678 4.7753 3.4523 17.2174
Sc-1 GDSC1 3.4845 5.5327 2.1112 5.4361
TALL-1 [Human adult T-ALL] CTRP2 3.5147 5.5541 3.4005 17.2453
Karpas-45 GDSC1 3.5154 7.3868 1.2199 12.1048
MOLT-16 GDSC1; CTRP2 3.5382 5.7586 3.3817 17.2379
SU-DHL-1 GDSC1; CTRP2 3.5433 5.6003 3.422 17.0798
SU-DHL-5 GDSC1 3.5632 6.0031 1.938 6.5367
L-540 GDSC1; CTRP2 3.6035 5.8308 3.4357 16.8434
U-937 CTRP2 3.6082 6.0391 3.3871 17.0036
PF-382 GDSC1; CTRP2 3.6154 5.463 3.5267 16.4856
KCL-22 GDSC1; CTRP2 3.6248 5.8249 3.4604 16.6897
MHH-PREB-1 GDSC1 3.6393 8.4182 0.8035 14.6342
RC-K8 GDSC1 3.671 7.0352 1.5106 9.4621
KE-97 CTRP2 3.6976 5.7717 3.5523 16.1373
Farage GDSC1 3.7037 6.2931 1.8967 6.4503
AMO1 GDSC1 3.7057 7.6245 1.2463 11.3078
JeKo-1 CTRP2 3.7073 6.3669 3.399 16.6623
Ki-JK CTRP2 3.7083 5.3406 3.6469 15.7723
P12-Ichikawa GDSC1; CTRP2 3.7085 5.8405 3.5478 16.1197
SUP-HD1 GDSC1; CTRP2 3.7142 6.7794 3.2686 17.1252
JSC-1 GDSC1 3.7188 5.5923 2.2428 3.8145
ARH-77 GDSC1 3.7554 5.7693 2.1829 4.166
YT GDSC1 3.7876 6.1936 2.0023 5.4276
A4/Fukuda GDSC1; CTRP2 3.7902 4.9345 3.7767 15.063
HuT 78 CTRP2 3.8277 6.006 3.6357 15.4385
ML-2 GDSC1 3.8325 6.9396 1.6735 7.77
DEL GDSC1; CTRP2 3.8456 5.5378 3.7617 14.9359
DND-41 GDSC1; CTRP2 3.8518 6.0172 3.659 15.281
NCI-H929 CTRP2 3.8722 5.1671 3.8434 14.5685
KMS-18 CTRP2 3.876 9.6265 2.233 20.6357
BL-41 GDSC1 3.887 9.603 0.4054 16.4158
Reh GDSC1; CTRP2 3.8945 6.271 3.6325 15.2482
TK [Human B-cell lymphoma] GDSC1 3.9085 6.0931 2.1291 4.1895
MOLM-6 CTRP2 3.9092 7.6582 3.1372 17.079
HT GDSC1; CTRP2 3.9349 5.6393 3.8389 14.3834
SUP-T11 CTRP2 3.9545 6.2073 3.7171 14.7597
BL-70 CTRP2 3.9732 6.433 3.6671 14.8874
MLMA GDSC1 3.9921 7.6579 1.4371 9.0681
Raji GDSC1; CTRP2 4.0201 5.4654 3.9621 13.6834
A3/Kawakami GDSC1; CTRP2 4.0221 6.6263 3.655 14.7896
Namalwa GDSC1; CTRP2 4.0257 7.3993 3.3657 15.8796
VL51 GDSC1 4.035 8.5526 1.0319 11.8356
DB GDSC1; CTRP2 4.0411 5.9931 3.8719 13.9367
HEL GDSC1; CTRP2 4.0431 5.4931 3.9824 13.5398
P31/FUJ GDSC1; CTRP2 4.0796 5.5446 4.013 13.3169
HuNS1 CTRP2 4.0798 7.2624 3.4779 15.2991
ST486 GDSC1; CTRP2 4.0857 6.3351 3.8209 13.9881
L-428 GDSC1; CTRP2 4.0931 6.6933 3.7081 14.3861
ALL-PO GDSC1 4.1075 8.9062 0.9113 12.4507
Kasumi-2 CTRP2 4.1174 5.7658 4.0104 13.207
CTB-1 GDSC1 4.1184 8.3812 1.1749 10.5935
BV-173 GDSC1; CTRP2 4.1299 6.8204 3.7016 14.3052
M-07e CTRP2 4.1324 5.8919 3.9974 13.2066
OCI-Ly19 GDSC1; CTRP2 4.1434 8.5128 3.0092 16.9564
MN-60 GDSC1 4.1457 6.86 1.9208 5.1374
KO52 CTRP2 4.1781 6.1498 3.9779 13.1373
CESS GDSC1 4.1864 6.1041 2.2896 2.4937
EHEB GDSC1; CTRP2 4.1973 6.8548 3.761 13.8891
Mono-Mac-1 CTRP2 4.2048 8.0583 3.2735 15.7588
NB4 GDSC1; CTRP2 4.2098 6.3304 3.9574 13.118
K-562 GDSC1; CTRP2 4.217 6.6721 3.8493 13.4994
BALL-1 GDSC1 4.2254 7.4529 1.6932 6.5868
NKM-1 GDSC1 4.2468 9.4589 0.7414 13.1777
Karpas-299 GDSC1; CTRP2 4.2539 7.3014 3.646 14.1732
DoHH2 GDSC1 4.275 8.2938 1.3255 9.0973
U266B1 GDSC1; CTRP2 4.2902 5.8662 4.1755 12.0839
IM-9 GDSC1 4.2989 6.1391 2.3351 2.013
RPMI-8226 GDSC1; CTRP2 4.2993 6.4208 4.0252 12.6037
WSU-NHL GDSC1 4.3123 6.4998 2.1849 2.9503
AML-193 CTRP2 4.331 6.1804 4.1356 12.1035
Ramos.2G6.4C10 GDSC1 4.3422 9.9487 0.5708 14.0007
NK-92MI GDSC1 4.3515 6.6004 2.1623 3.0264
GR-ST GDSC1 4.3598 8.2945 1.3822 8.473
F-36P CTRP2 4.363 6.2307 4.1554 11.9355
MM1.S CTRP2 4.3639 6.1756 4.1729 11.8687
RCH-ACV CTRP2 4.3688 8.6718 3.164 15.7696
MOTN-1 CTRP2 4.3706 7.7474 3.5796 14.1196
LC4-1 GDSC1 4.3927 8.9843 1.074 10.5356
Mono-Mac-6 GDSC1; CTRP2 4.4136 9.2721 2.9294 16.5882
JJN-3 GDSC1; CTRP2 4.4392 5.8409 4.3436 11.0244
L-363 GDSC1; CTRP2 4.4546 6.4041 4.1993 11.5029
MOLP-8 GDSC1; CTRP2 4.4656 6.3873 4.2169 11.4051
MC116 GDSC1; CTRP2 4.4739 6.0279 4.3349 10.9485
HC-1 GDSC1 4.4908 8.8662 1.197 9.4297
HH [Human lymphoma] GDSC1 4.5009 12.0606 -0.3485 18.8093
PL21 CTRP2 4.5121 6.5701 4.204 11.3187
TUR GDSC1 4.5326 10.1353 0.6148 13.183
RL GDSC1; CTRP2 4.5621 7.0762 4.0625 11.7195
SCC-3 GDSC1 4.563 10.4467 0.4851 13.91
JVM-2 GDSC1 4.5895 8.6551 1.362 8.0391
THP-1 GDSC1; CTRP2 4.5897 7.2747 4.0091 11.853
OCI-AML-3 GDSC1; CTRP2 4.6072 6.0811 4.4658 10.0706
KMS-27 CTRP2 4.6124 7.099 4.1061 11.4137
P3HR-1 CTRP2 4.6209 7.1186 4.1069 11.3878
HEL 92.1.7 CTRP2 4.6263 6.8726 4.2121 10.9662
BC-3 GDSC1 4.653 7.7771 1.8079 4.8157
L-1236 GDSC1 4.6582 8.3329 1.5562 6.5319
KY821 GDSC1 4.7004 7.7769 1.8357 4.5326
EJM GDSC1; CTRP2 4.7229 7.0839 4.2282 10.6402
HPB-ALL CTRP2 4.7248 8.4621 3.6147 13.0785
OCI-AML-5 GDSC1; CTRP2 4.731 5.7027 4.6878 8.8971
TF-1 CTRP2 4.8114 8.1422 3.849 11.9196
ME1 GDSC1 4.8131 5.9872 2.6207 0.2208
HD-MY-Z CTRP2 4.8601 7.7961 4.0567 10.9622
MHH-CALL-3 CTRP2 4.9053 6.7891 4.5409 8.9308
SEM CTRP2 4.9278 8.0678 3.9989 11.027
MOLT-4 GDSC1 4.94 6.4157 2.516 0.4548
BE-13 GDSC1 4.952 11.7433 0.1288 14.9614
Karpas-422 GDSC1; CTRP2 4.9654 7.545 4.2768 9.814
Granta-519 GDSC1; CTRP2 4.9772 8.601 3.7956 11.7339
CCRF-CEM GDSC1 4.9951 6.7925 2.398 0.8555
NOMO-1 GDSC1; CTRP2 5.0201 7.1108 4.5256 8.6828
SUP-B15 GDSC1; CTRP2 5.1019 9.1139 3.6675 11.9666
Karpas-620 GDSC1 5.1813 6.6332 2.5299 0.2988
KOPN-8 GDSC1 5.1844 7.0442 2.3818 0.7722
SIG-M5 GDSC1; CTRP2 5.1997 6.5189 4.9603 6.504
MHH-CALL-4 CTRP2 5.2028 8.9056 3.8635 10.9293
SET-2 CTRP2 5.2034 7.1681 4.6874 7.5663
Loucy GDSC1 5.2105 6.9055 2.4436 0.5342
PL-21 GDSC1 5.2312 7.9754 2.0338 2.414
Jiyoye GDSC1 5.3122 6.9856 2.454 0.4465
HAL-01 GDSC1 5.3182 7.1961 2.3797 0.6865
HL-60 GDSC1; CTRP2 5.3802 6.592 5.121 5.389
ROS-50 GDSC1 5.4176 7.7269 2.2201 1.2544
RPMI-8866 GDSC1 5.4184 11.5372 0.5393 11.3805
CMK CTRP2 5.4348 8.6903 4.1844 9.0797
H9 GDSC1 5.5144 6.9647 2.5352 0.1809
REC-1 CTRP2 5.55 10.83 3.2281 12.7901
Ci-1 CTRP2 5.5694 6.1905 5.4799 3.486
ME1 CTRP2 5.5759 6.1764 5.4918 3.4226
ATN-1 GDSC1 5.6228 14.0588 -0.5257 16.6939
MOLP-2 CTRP2 5.6239 6.2665 5.5102 3.2166
OCI-M1 GDSC1; CTRP2 5.6422 7.7279 4.8478 5.864
SR GDSC1; CTRP2 5.7442 8.1844 4.715 6.1958
KMOE-2 GDSC1 5.7736 7.3987 2.4787 0.2149
MOLT-13 CTRP2 5.8774 7.3041 5.2705 3.5904
DG-75 GDSC1 6.0273 7.7666 2.4427 0.2137
SK-MM-2 GDSC1; CTRP2 6.0919 9.4986 4.3567 7.0021
OCI-Ly10 CTRP2 7.5427 14.3152 3.0815 9.7465
⏷ Show the Full List of 210 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 4.4959 9.233 3.0284 15.9929
TE15 CTRP2 5.2516 10.727 3.0135 14.3023
TE-8 GDSC1 1.7484 5.9238 0.3981 24.8809
TE-15 GDSC1 2.5893 6.903 0.6964 19.2029
T.T GDSC1 3.4062 8.537 0.5623 17.0165
KYSE-270 GDSC1 3.5499 6.2415 1.8116 7.5449
KYSE-70 GDSC1; CTRP2 3.8322 7.1578 3.2556 16.8383
TE-6 GDSC1; CTRP2 4.5194 6.3442 4.2895 10.9785
TE-10 GDSC1; CTRP2 4.5926 6.4985 4.3164 10.665
TE-5 GDSC1; CTRP2 4.7383 7.0203 4.2707 10.4329
TE-11 GDSC1; CTRP2 4.8634 11.3384 2.3586 17.7546
KYSE-410 GDSC1; CTRP2 5.0299 7.8509 4.2007 9.9592
OE21 GDSC1; CTRP2 5.0765 8.2403 4.0633 10.4049
KYSE-140 GDSC1; CTRP2 5.112 10.2541 3.1196 14.1822
TE-9 GDSC1; CTRP2 5.5514 9.1932 4.0424 9.4161
EC-GI-10 GDSC1; CTRP2 5.746 9.9639 3.8307 9.8912
TE-1 GDSC1; CTRP2 6.2832 9.8707 4.3264 6.7726
COLO 680N GDSC1; CTRP2 6.6282 9.7852 4.6354 4.8863
OE19 GDSC1; CTRP2 6.6419 12.0756 3.5111 9.5195
OE33 GDSC1; CTRP2 6.6705 8.6624 5.2132 2.4541
KYSE-520 GDSC1; CTRP2 6.7008 11.7422 3.7223 8.5482
TE-14 CTRP2 6.7187 9.3642 4.9074 3.6242
KYSE-150 GDSC1; CTRP2 7.0007 21.3841 -0.8438 23.512
KYSE-180 GDSC1; CTRP2 7.1593 13.7966 3.0536 10.4801
TE-4 CTRP2 7.244 10.5872 4.6781 3.7983
KYSE-510 GDSC1; CTRP2 7.2982 9.607 5.1677 1.8542
KYSE-450 GDSC1; CTRP2 7.6487 11.3144 4.5962 3.5976
KYSE-30 CTRP2 7.9615 11.3814 4.7536 2.6547
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 6.4541 10.2853 4.2549 6.7657
KP-1N GDSC1 3.2872 6.2228 1.6212 9.8437
MZ-PC-1 GDSC1 3.5265 6.7784 1.5296 9.7658
Panc 10.05 GDSC1 3.6851 9.9283 0.089 18.9614
MIA PaCa-2 GDSC1; CTRP2 3.8732 9.8276 2.1372 21.0005
BxPC-3 GDSC1; CTRP2 4.2021 7.4888 3.5144 14.8236
HPAC GDSC1; CTRP2 4.2284 6.8105 3.811 13.6117
PL4 GDSC1 4.2356 6.3679 2.2002 2.993
HuP-T4 GDSC1; CTRP2 4.2465 7.7601 3.4459 14.9722
PSN1 GDSC1; CTRP2 4.3277 9.4858 2.7448 17.5276
SNU-213 CTRP2 4.5252 6.413 4.2729 11.023
KP-4 GDSC1; CTRP2 4.8136 9.3645 3.273 14.2471
Panc 08.13 GDSC1; CTRP2 5.3068 7.5731 4.6031 7.6504
L3.3 CTRP2 5.3827 8.1941 4.3783 8.3945
PK-59 CTRP2 5.4334 8.1612 4.4419 8.016
HPAF-II GDSC1; CTRP2 5.4962 11.0748 3.0589 13.5921
DAN-G GDSC1; CTRP2 5.6283 11.7296 2.8481 14.1642
KP-3 GDSC1; CTRP2 5.6344 11.9846 2.726 14.6375
Panc 03.27 GDSC1; CTRP2 5.7382 11.3197 3.1475 12.7291
SU.86.86 GDSC1; CTRP2 5.7775 8.0354 4.8186 5.6921
SW1990 GDSC1; CTRP2 5.8308 11.9456 2.914 13.4857
QGP-1 CTRP2 5.9517 9.6244 4.1765 8.0306
Capan-1 GDSC1; CTRP2 6.0475 7.5939 5.2722 3.2399
CFPAC-1 GDSC1; CTRP2 6.0513 11.7887 3.178 11.9798
HuP-T3 GDSC1; CTRP2 6.0867 9.1941 4.5046 6.3908
YAPC GDSC1; CTRP2 6.1374 10.7694 3.7589 9.4177
TCC-Pan2 CTRP2 6.1908 9.7111 4.3316 6.9208
PaTu 8988s CTRP2 6.2121 10.3866 4.0114 8.2228
SUIT-2 GDSC1; CTRP2 6.3623 10.0486 4.3007 6.737
PANC-1 CTRP2 6.7012 9.8738 4.6457 4.7263
PaTu 8988t GDSC1; CTRP2 6.7224 8.075 5.5231 1.1769
PK-45H CTRP2 6.7513 12.1308 3.5683 9.0942
Panc 04.03 GDSC1; CTRP2 6.7769 10.1131 4.5835 4.8627
Panc 05.04 CTRP2 6.9244 10.1018 4.694 4.1856
Capan-2 GDSC1; CTRP2 6.9271 11.685 3.9217 7.3473
AsPC-1 GDSC1; CTRP2 7.0073 11.3583 4.1409 6.3189
Panc 02.03 GDSC1; CTRP2 7.2723 9.9481 4.9962 2.5236
Hs 766T GDSC1; CTRP2 7.4006 10.9609 4.6037 3.8834
KP-2 GDSC1; CTRP2 7.872 16.3381 2.3298 12.0978
PaTu 8902 GDSC1; CTRP2 8.0034 9.6011 5.5162 0.3169
SNU-410 CTRP2 8.2211 10.3171 5.3357 0.6179
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 6.1988 12.6573 2.8657 12.9541
LB2518-MEL GDSC1 2.0264 8.8436 -0.7682 29.6106
G-mel GDSC1 2.1678 9.1867 -0.8116 29.1917
G-361 GDSC1; CTRP2 2.275 5.589 2.0456 25.8995
SH-4 GDSC1 2.5751 9.1235 -0.4227 25.7492
IST-MEL1 GDSC1 2.7246 7.3725 0.5802 19.4283
M14 GDSC1 2.7971 3.7222 2.4584 5.068
A-388 GDSC1 2.8316 4.1806 2.2641 6.4437
A-431 GDSC1 2.9036 6.1631 1.3374 13.3756
WM1552C GDSC1 2.9319 7.6698 0.6081 18.4395
CP50-MEL-B GDSC1 3.0365 26.9942 -8.9667 40.9473
COLO 679 GDSC1 3.0862 8.8637 0.1397 20.7642
LB373-MEL-D GDSC1 3.1483 6.5999 1.3221 12.5965
MZ-MEL-2 GDSC1 3.2148 9.7008 -0.1732 22.0437
HMV-II GDSC1 3.3746 13.7014 -2.0418 29.2876
GAK GDSC1 3.7618 7.3355 1.4298 9.7902
WM278 GDSC1 3.784 9.9452 0.1572 18.2409
COLO 792 GDSC1; CTRP2 3.8121 5.1212 3.7846 14.9645
VMRC-MELG GDSC1 4.1854 8.5126 1.1582 10.5225
MMAc-SF GDSC1 4.2162 9.7205 0.5915 14.2367
451Lu GDSC1 4.3008 6.5454 2.1581 3.1495
CP66-MEL GDSC1 4.4353 9.7241 0.746 12.6118
LOX-IMVI GDSC1; CTRP2 4.4483 6.3443 4.2123 11.4732
MZ-MEL-7 GDSC1 4.541 10.5462 0.4213 14.3635
WM88 CTRP2 4.5617 7.5843 3.8474 12.5622
HT-144 GDSC1; CTRP2 4.6334 9.451 3.0585 15.5392
DJM-1 GDSC1 4.7389 9.8369 0.8996 10.7926
CHL-1 GDSC1 4.7738 9.3056 1.1745 8.873
Hs 294T CTRP2 4.8093 9.3924 3.2554 14.328
COLO 783 GDSC1 4.9016 6.2945 2.545 0.3851
WM115 GDSC1; CTRP2 4.956 7.0337 4.4925 8.9821
IGR-37 GDSC1; CTRP2 5.0616 8.7316 3.8141 11.4589
RPMI-7951 GDSC1; CTRP2 5.0802 9.4263 3.4952 12.7229
Hs 936.T CTRP2 5.168 6.5737 4.905 6.8041
MDA-MB-435S CTRP2 5.2221 8.5413 4.0584 10.0824
SK-MEL-5 GDSC1; CTRP2 5.2765 8.6147 4.0741 9.8927
WM1799 CTRP2 5.2827 8.6766 4.0499 9.9785
Mel Ho GDSC1; CTRP2 5.385 9.8509 3.5671 11.7479
WM266-4 CTRP2 5.3937 8.5407 4.2197 9.0251
Hs 938.T GDSC1 5.4276 11.6225 0.5051 11.5638
MeWo GDSC1; CTRP2 5.5672 9.6198 3.8449 10.2049
CJM [Human melanoma] CTRP2 5.6325 8.7702 4.3246 8.0651
HMCB CTRP2 5.6599 8.3353 4.5646 7.0043
A101D GDSC1; CTRP2 5.6829 6.2438 5.582 2.7775
WM35 GDSC1 5.7078 15.6904 -1.2548 19.7867
COLO 800 GDSC1; CTRP2 5.746 8.0592 4.7787 5.9255
COLO 829 GDSC1; CTRP2 5.7648 7.8873 4.8807 5.459
IGR-1 GDSC1; CTRP2 5.777 7.0402 5.3092 3.6484
IPC-298 GDSC1; CTRP2 5.7775 12.1193 2.7818 14.122
Hs 895.T CTRP2 5.8178 13.3323 2.21 16.26
A2058 GDSC1; CTRP2 5.8801 6.4871 5.6747 1.903
K029AX CTRP2 5.979 7.3004 5.3611 3.0011
WT2-iPS GDSC1; CTRP2 6.0641 8.8121 4.677 5.7097
SK-MEL-24 GDSC1; CTRP2 6.0893 9.4396 4.3841 6.8921
SK-MEL-2 GDSC1; CTRP2 6.1093 7.502 5.3689 2.7164
Hs 940.T GDSC1; CTRP2 6.2468 14.4915 1.9883 16.2324
WM793 GDSC1; CTRP2 6.3295 11.1211 3.7396 9.1385
UACC-62 GDSC1; CTRP2 6.3457 9.4607 4.5804 5.5958
IGR-39 CTRP2 6.3602 11.3567 3.6466 9.4677
WM983B CTRP2 6.3716 10.3474 4.1591 7.3127
Hs 944.T CTRP2 6.4121 15.4079 1.6654 17.0789
A-375 GDSC1; CTRP2 6.6362 11.1572 3.9629 7.6645
SK-MEL-1 GDSC1; CTRP2 6.7227 9.0065 5.0835 2.9024
Mel JuSo GDSC1; CTRP2 6.7758 11.2895 4.0037 7.2592
UACC-257 GDSC1; CTRP2 6.8599 11.9233 3.7538 8.1484
Hs 688(A).T CTRP2 6.9295 9.47 5.0012 2.942
SK-MEL-31 CTRP2 6.9934 10.4893 4.5546 4.65
SK-MEL-30 GDSC1; CTRP2 7.0232 12.0403 3.8179 7.6169
SK-MEL-3 GDSC1; CTRP2 7.024 10.7525 4.4484 5.0363
Hs 934.T CTRP2 7.0425 9.1815 5.209 1.9879
SK-MEL-28 GDSC1; CTRP2 7.1839 7.9784 5.7861 0.101
RVH-421 GDSC1; CTRP2 7.2493 12.6678 3.6753 7.8368
Hs 852.T CTRP2 8.254 13.8981 3.771 6.017
COLO 741 CTRP2 10.3213 30.3443 -2.7517 22.5866
Hs 839.T CTRP2 12.1619 30.099 -1.346 17.1098
EquiPSC Line K2 GDSC1 5.1321 10.9083 0.6504 11.3933
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCE-4 GDSC1 2.7666 8.9997 -0.1965 23.8446
TE-12 GDSC1 3.0527 6.2528 1.4173 12.2206
KYSE-50 GDSC1 4.2117 17.9997 -3.5155 30.8989
KYSE-220 GDSC1 5.98 7.8638 2.3926 0.3265
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; CTRP2 4.3022 6.4926 4.0042 12.6731
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-7 GDSC1 0.3821 2.4332 0.2755 33.3724
SK-N-DZ GDSC1; CTRP2 2.224 6.7165 1.6739 27.3502
IMR-32 CTRP2 2.5055 5.0006 2.409 23.9046
SK-N-MC-IXC GDSC1 2.5437 13.7743 -2.772 34.0492
NH-12 GDSC1 3.1455 6.2276 1.5058 11.2154
GI-ME-N GDSC1 3.1571 12.325 -1.5322 28.2733
SiMa GDSC1; CTRP2 4.2092 6.6501 3.8487 13.5243
NB1 GDSC1; CTRP2 4.218 6.0532 4.0488 12.7599
SK-N-SH GDSC1; CTRP2 4.2522 8.7818 2.9969 16.7256
KP-N-SI9s CTRP2 4.5147 7.415 3.8717 12.5911
IMR-5 GDSC1 4.5648 6.6853 2.2401 2.175
SK-N-FI GDSC1; CTRP2 4.6345 7.1851 4.0935 11.4032
MHH-NB-11 GDSC1; CTRP2 4.64 6.6292 4.32 10.516
SK-N-BE(2)-M17 GDSC1 4.6849 6.3116 2.4498 0.9048
SJNB-6 GDSC1 4.795 13.9418 -1.0565 21.323
NH-6 CTRP2 4.8774 7.2583 4.3145 9.8907
SJNB-13 GDSC1 4.9075 6.8708 2.3293 1.2484
TGW GDSC1 4.9185 6.5398 2.4616 0.6607
GOTO GDSC1 4.9663 7.3712 2.1541 2.0982
SJNB-10 GDSC1 5.0427 6.8432 2.3988 0.8137
SJNB-12 GDSC1 5.0441 8.584 1.6713 4.9506
Kelly GDSC1; CTRP2 5.0912 6.9917 4.6505 8.0031
NB(TU)1 GDSC1 5.1028 6.739 2.462 0.5369
SK-N-AS GDSC1; CTRP2 5.1144 7.0062 4.6682 7.8728
SJNB-14 GDSC1 5.1386 6.6883 2.4943 0.4151
LA-N-6 GDSC1 5.2077 7.2587 2.3101 1.0473
NB69 GDSC1 5.232 7.5019 2.226 1.408
CHP-212 GDSC1; CTRP2 5.4713 8.5911 4.2667 8.6567
KP-N-YS GDSC1 5.4861 7.5554 2.3142 0.8115
KP-N-YN GDSC1; CTRP2 5.578 8.4199 4.4486 7.6655
SJNB-5 GDSC1 5.7658 7.5193 2.4345 0.307
CHP-126 GDSC1; CTRP2 6.3679 8.065 5.2894 2.6013
SK-N-BE(2) CTRP2 6.769 9.7481 4.7561 4.1662
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 2.3058 7.3672 1.5396 27.556
HuCC-T1 GDSC1; CTRP2 5.0644 8.1684 4.0856 10.3427
SNU-1196 CTRP2 5.0657 7.2405 4.5152 8.6056
SNU-478 CTRP2 5.1336 7.8009 4.3263 9.196
HuH-28 CTRP2 6.823 10.7833 4.2884 6.0056
SNU-245 CTRP2 7.2137 10.9886 4.4659 4.6878
SNU-308 CTRP2 7.4399 9.5363 5.2785 1.3242
SNU-869 CTRP2 7.6651 16.0719 2.3089 12.5093
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 89 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCUB-M GDSC1 1.7926 4.2082 1.2308 19.019
Hs 578T GDSC1; CTRP2 1.9534 6.0683 1.5732 28.549
EFM-19 GDSC1 2.3622 9.6798 -0.8853 28.702
HCC1569 GDSC1 2.9076 5.6077 1.6184 11.2107
AU565 GDSC1 3.3133 16.9759 -3.7286 33.8157
MRK-nu-1 GDSC1 3.8047 7.2848 1.4856 9.2494
DU4475 GDSC1 3.9251 5.7004 2.3206 2.7905
MCF-7 GDSC1; CTRP2 4.2441 6.8719 3.8047 13.591
HCC1954 GDSC1; CTRP2 4.2572 7.5506 3.5462 14.5519
ZR-75-30 GDSC1; CTRP2 4.2671 9.8429 2.5173 18.563
HCC2218 GDSC1; CTRP2 4.3215 7.3045 3.7158 13.7183
MFM-223 GDSC1 4.4718 9.8812 0.6954 12.8373
HCC70 GDSC1 4.4758 9.4239 0.9193 11.3569
MDA-MB-436 GDSC1 4.4786 7.98 1.608 6.5846
T-47D GDSC1; CTRP2 4.489 7.0988 3.9762 12.2532
MDA-MB-415 GDSC1 4.529 13.1167 -0.8475 21.1462
MDA-MB-157 GDSC1 4.5601 14.1698 -1.344 23.1863
UACC-812 GDSC1 4.5614 6.9791 2.1116 2.9782
HCC1187 GDSC1 4.58 9.9216 0.7511 12.1807
CAL-51 GDSC1; CTRP2 4.7064 6.927 4.2751 10.5026
Evsa-T GDSC1 4.7156 6.9083 2.2227 2.0554
BT-474 GDSC1; CTRP2 4.7432 8.1732 3.7669 12.4199
HCC1395 GDSC1; CTRP2 4.8978 10.1349 2.9795 15.2338
MDA-MB-453 GDSC1; CTRP2 4.8979 7.9199 4.0378 10.9438
COLO 824 GDSC1 5.0031 9.4765 1.2399 7.8971
HCC1599 GDSC1 5.0448 9.3758 1.3122 7.3235
HCC1500 GDSC1; CTRP2 5.0881 9.8423 3.2995 13.505
HCC1419 GDSC1; CTRP2 5.0913 8.7055 3.855 11.222
MDA-MB-468 GDSC1; CTRP2 5.1569 10.212 3.1815 13.8307
BT-483 GDSC1 5.2113 6.9487 2.4281 0.5856
MDA-MB-175-VII GDSC1 5.2154 6.874 2.457 0.4885
HMC-1-8 CTRP2 5.2177 8.3718 4.1361 9.7733
UACC-893 GDSC1 5.2901 7.6335 2.2002 1.472
HCC2157 GDSC1 5.4859 7.0678 2.4897 0.2805
EFM-192A GDSC1; CTRP2 5.5587 14.8709 1.2201 20.333
JIMT-1 GDSC1; CTRP2 5.5819 9.9151 3.7113 10.7294
KPL-1 CTRP2 5.6462 7.8407 4.7961 6.0696
BT-549 GDSC1; CTRP2 5.6937 8.5068 4.51 7.1598
BT-20 GDSC1; CTRP2 5.8829 10.1155 3.8728 9.4388
MDA-MB-361 GDSC1; CTRP2 5.9359 9.1109 4.4198 7.0409
HCC1143 CTRP2 6.0805 10.438 3.8776 9.0315
CAL-85-1 GDSC1; CTRP2 6.0919 10.921 3.6456 9.9761
HCC1937 GDSC1; CTRP2 6.1889 9.381 4.4949 6.2391
HCC38 GDSC1; CTRP2 6.206 10.3589 4.0203 8.197
MDA-MB-231 GDSC1; CTRP2 6.2266 11.268 3.5828 9.9801
CAL-120 GDSC1; CTRP2 6.3432 9.1871 4.7146 5.0389
MDA-MB-330 GDSC1 6.4277 15.4157 -0.6364 15.3447
CAL-148 GDSC1; CTRP2 6.5275 8.8846 5.004 3.5243
CAMA-1 GDSC1; CTRP2 6.5523 9.1958 4.8693 4.0412
HCC1428 GDSC1; CTRP2 6.7552 12.8425 3.218 10.5139
HCC202 GDSC1; CTRP2 6.7819 14.3454 2.4914 13.3355
SK-BR-3 CTRP2 6.7881 9.4623 4.9085 3.5157
Hs 578Bst CTRP2 6.8527 8.768 5.2828 1.9359
HCC1806 GDSC1; CTRP2 6.8982 11.8242 3.8315 7.7653
ZR-75-1 CTRP2 7.4201 9.4929 5.2867 1.3144
HDQ-P1 GDSC1; CTRP2 7.4207 10.8578 4.6652 3.6163
BT 440 CTRP2 1.1836 6.0183 0.7467 33.766
BT 416 CTRP2 2.1911 5.2415 2.028 26.2274
BT147 CTRP2 3.8472 15.6392 -0.688 29.7036
BT 231 CTRP2 4.072 7.3891 3.4187 15.5484
BT 172 CTRP2 4.286 6.7875 3.8813 13.182
BT 504 CTRP2 4.3128 11.4816 1.7756 21.2227
BT 428 CTRP2 4.4294 8.1375 3.4676 14.4097
BT 145 CTRP2 4.811 7.9947 3.9166 11.6483
BT 239 CTRP2 4.8876 6.1563 4.7497 8.1932
BT 159 CTRP2 4.9517 6.5367 4.6888 8.2349
BT 228 CTRP2 5.088 9.0407 3.6899 11.9071
BT 216 CTRP2 5.1263 14.6164 0.9712 22.0844
BT 112 CTRP2 5.1721 8.1664 4.1909 9.6557
BT164 CTRP2 5.1934 7.5832 4.487 8.398
BT 139 CTRP2 5.2514 8.7323 3.9934 10.2831
BT 482 CTRP2 5.2557 9.2166 3.761 11.2326
BT 248 CTRP2 5.6421 9.4069 4.0172 9.3287
BT 330 CTRP2 5.6527 12.5171 2.4761 15.5801
BT 271 CTRP2 5.6907 16.8329 0.3526 22.7891
BT 187 CTRP2 5.7626 8.031 4.8075 5.7698
BT 179 CTRP2 5.8157 7.5868 5.0752 4.5379
BT 286 CTRP2 5.8839 15.0004 1.432 18.939
BT 232 CTRP2 5.9262 13.6054 2.1649 16.2101
BT 224 CTRP2 6.5185 10.8961 4.0015 7.7089
BT 359 CTRP2 6.8277 13.3455 3.0243 11.1646
BT 340 CTRP2 7.1488 13.4221 3.2307 9.7917
BT 328 CTRP2 7.1758 14.528 2.7046 11.822
BT 131 CTRP2 7.1804 10.8735 4.4984 4.6044
BT 320 CTRP2 7.3908 11.2899 4.4411 4.5393
BT 444 CTRP2 7.5412 20.4352 0.0552 20.1508
BT 422 CTRP2 8.0045 19.4267 0.9082 16.7896
BT 333 CTRP2 8.832 18.6614 1.8809 12.2435
BT 498 CTRP2 10.3564 26.2365 -0.7229 17.9092
⏷ Show the Full List of 89 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 6.0506 8.2616 4.941 4.6262
Cancer Drug Sensitivity Data Curated from 66 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GI-1 GDSC1 0.4095 10.1699 -2.9206 42.6143
M059J GDSC1 1.5151 8.0754 -0.8611 32.3033
H4 GDSC1 1.6703 7.5065 -0.4389 29.7631
MOG-G-UVW GDSC1 1.8544 16.1766 -4.5657 39.5354
SF539 GDSC1; CTRP2 2.3465 5.6348 2.1128 25.4394
LN-405 GDSC1 2.476 3.3595 2.3015 7.758
SNU-1105 CTRP2 2.6413 4.6169 2.6013 22.8066
DK-MG GDSC1; CTRP2 2.7601 7.7954 1.8661 25.0559
KS-1 [Human Krukenberg tumour] GDSC1 2.808 9.3214 -0.3221 24.3349
D-502MG GDSC1 2.8258 7.2697 0.7183 18.1133
D-542MG GDSC1 3.0156 21.6149 -6.2945 38.5587
D-566MG GDSC1 3.0931 8.264 0.4452 18.8848
D-392MG GDSC1 3.3026 13.4355 -1.9678 29.281
MOG-G-CCM GDSC1 3.608 10.554 -0.283 21.2588
GaMG GDSC1; CTRP2 3.7219 10.086 1.8674 22.3827
D283 Med GDSC1; CTRP2 3.8292 6.0129 3.6354 15.4352
D-423MG GDSC1 3.9301 8.0462 1.2038 10.9336
D-263MG GDSC1 4.0734 9.8855 0.4057 15.8324
42-MG-BA GDSC1; CTRP2 4.3021 12.4472 1.296 22.9183
SNU-466 CTRP2 4.4006 7.5059 3.7144 13.5109
SNU-738 CTRP2 4.5358 7.7676 3.7406 13.0518
LN-18 GDSC1; CTRP2 4.5491 8.9372 3.2195 15.0994
Onda 11 GDSC1 4.5973 13.6401 -1.0546 21.8706
LNZTA3WT4 GDSC1 4.6097 10.2606 0.6079 13.0143
PFSK-1 GDSC1 4.6329 7.534 1.9058 4.1957
SK-MG-1 GDSC1 4.7792 9.4409 1.1142 9.2656
Onda 10 GDSC1 4.8639 6.8318 2.325 1.3163
AM-38 GDSC1 4.9642 7.3623 2.1568 2.0861
Hs 683 GDSC1; CTRP2 5.0033 10.8233 2.7401 15.9484
SNU-201 CTRP2 5.0258 12.8238 1.7724 19.5704
A-172 GDSC1; CTRP2 5.0587 13.6802 1.3769 20.8858
CAS-1 GDSC1; CTRP2 5.1417 11.926 2.3211 17.2722
KNS-81-FD GDSC1 5.1499 12.0329 0.1253 14.4622
LN-229 GDSC1; CTRP2 5.2415 8.6781 4.0105 10.2352
YH-13 GDSC1; CTRP2 5.585 12.7361 2.3084 16.3671
T98G GDSC1; CTRP2 5.5919 17.4144 -0.0219 24.0668
KNS-60 CTRP2 5.6443 10.6907 3.38 11.97
SF268 GDSC1; CTRP2 5.8362 9.816 3.9824 9.0741
TM-31 CTRP2 5.949 9.2111 4.3809 7.1781
CCF-STTG1 CTRP2 5.9876 13.7497 2.1443 16.1643
SF126 GDSC1; CTRP2 6.0278 13.2766 2.4145 15.0574
ONS-76 GDSC1; CTRP2 6.1659 9.634 4.3498 6.8912
SNU-489 CTRP2 6.1674 10.544 3.8962 8.7882
SW1088 GDSC1; CTRP2 6.2754 14.3397 2.0877 15.8096
Daoy GDSC1; CTRP2 6.2915 12.1693 3.1854 11.4896
SNB-75 GDSC1; CTRP2 6.3645 12.4301 3.1143 11.6412
NMC-G1 GDSC1; CTRP2 6.444 9.3189 4.7271 4.8121
YKG-1 GDSC1; CTRP2 6.4813 7.723 5.5353 1.429
KINGS-1 GDSC1 6.5698 17.2777 -1.4277 18.4883
DBTRG-05MG GDSC1; CTRP2 6.6057 10.6224 4.2047 6.7126
KALS-1 GDSC1; CTRP2 6.7168 9.7879 4.6992 4.4812
GB-1 GDSC1; CTRP2 6.761 13.7713 2.7607 12.3269
M059K CTRP2 6.8111 10.5984 4.3705 5.6863
GOS-3 CTRP2 6.8114 11.0353 4.1558 6.5718
8-MG-BA GDSC1; CTRP2 6.9002 11.1239 4.1778 6.3373
U-118MG GDSC1; CTRP2 6.9898 16.6307 1.517 16.522
KNS-81 CTRP2 7.0379 8.5247 5.5016 0.9344
SNU-626 CTRP2 7.1694 12.5438 3.6779 7.9529
GMS-10 CTRP2 7.264 12.1265 3.95 6.7002
U-251MG GDSC1; CTRP2 7.3549 10.7023 4.6961 3.5808
SF295 GDSC1; CTRP2 7.4731 12.8616 3.7406 7.2291
KG-1-C CTRP2 7.5229 8.8681 5.5933 0.3491
U-87MG ATCC GDSC1; CTRP2 7.588 11.0435 4.6842 3.3343
SW1783 GDSC1; CTRP2 7.6828 18.581 1.0837 16.7634
Becker GDSC1; CTRP2 9.4956 19.6345 1.8658 11.356
KNS-42 GDSC1; CTRP2 13.4341 26.6996 1.0314 9.396
⏷ Show the Full List of 66 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1 3.7912 6.0183 2.0884 4.7764
TGBC1TKB GDSC1 4.2703 9.2884 0.8413 12.4498
ETK-1 GDSC1 4.5723 9.3401 1.0252 10.3889
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2 0.6342 4.4033 0.4937 36.4788
AN3-CA GDSC1; CTRP2 0.7263 10.6327 -1.4344 40.1708
JHUEM-1 CTRP2 3.7497 5.8337 3.5944 15.8262
RL95-2 CTRP2 4.1966 6.3308 3.9429 13.2101
EN GDSC1; CTRP2 4.2814 7.1774 3.7252 13.7916
HEC-151 CTRP2 4.4 6.5106 4.1039 12.0173
JHUEM-7 CTRP2 4.4893 7.0477 3.9971 12.1716
HEC-265 CTRP2 4.5048 7.3339 3.8956 12.5237
HEC-59 CTRP2 4.5675 7.7104 3.7982 12.7417
MFE-280 GDSC1 4.623 12.0797 -0.2685 18.0424
HEC-1-B CTRP2 4.6412 6.8956 4.2188 10.8992
HEC-6 CTRP2 4.8139 7.9367 3.9461 11.5225
ESS-1 GDSC1; CTRP2 5.1642 9.7737 3.4036 12.908
HEC-50B CTRP2 5.4906 9.7062 3.7337 10.8302
MFE-296 GDSC1; CTRP2 5.5028 9.6861 3.7546 10.7177
HEC-108 CTRP2 5.8809 9.5343 4.1614 8.2348
HEC-251 CTRP2 5.961 9.9872 4.0031 8.7392
KLE GDSC1; CTRP2 6.2069 10.9903 3.7055 9.5085
JHUEM-3 CTRP2 6.7091 11.8342 3.6831 8.6957
MFE-319 GDSC1; CTRP2 6.7468 11.2362 4.0081 7.2895
HEC-1-A CTRP2 6.829 10.3502 4.5052 5.1031
EFE-184 CTRP2 8.0757 13.6488 3.7726 6.2462
Ishikawa (Heraklio) 02 ER- CTRP2 5.1673 7.8658 4.3288 9.1041
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-704 GDSC1 0.3659 4.2057 -0.275 36.3061
LB1047-RCC GDSC1 1.3505 7.7178 -0.8433 33.0275
BB65-RCC GDSC1 2.87 7.6679 0.5569 19.011
SW13 GDSC1 3.5199 8.5886 0.6262 16.2122
RXF 393L GDSC1 3.5558 10.5691 -0.3319 21.6885
A-498 GDSC1 3.9233 8.4449 1.0034 12.3673
LB996-RCC GDSC1 4.017 7.4127 1.5729 8.005
HA7-RCC GDSC1 4.1594 9.0654 0.8709 12.5719
TK-10 GDSC1 4.1801 10.9464 -0.0377 18.103
LB2241-RCC GDSC1 4.5972 8.4017 1.4859 7.1602
SN12C GDSC1 4.6536 10.5399 0.5034 13.5472
CAL-54 GDSC1; CTRP2 4.8501 8.6585 3.6451 12.6505
769-P GDSC1; CTRP2 5.0971 11.1667 2.6565 16.0681
786-O GDSC1; CTRP2 5.2321 11.5384 2.5942 16.0151
OS-RC-2 GDSC1; CTRP2 5.418 12.1168 2.4716 16.0916
KMRC-2 CTRP2 5.5613 9.8226 3.739 10.6579
KMRC-1 GDSC1; CTRP2 5.6819 10.7223 3.3969 11.8225
SW156 GDSC1 5.7381 8.017 2.2447 0.8934
BFTC-909 GDSC1; CTRP2 5.8378 8.5694 4.6059 6.4575
KMRC-3 CTRP2 6.0701 12.5443 2.8158 13.4024
SNU-1272 CTRP2 6.3154 9.8201 4.3774 6.5005
TUHR14TKB CTRP2 6.6284 11.712 3.6814 8.8428
UO-31 GDSC1; CTRP2 6.8236 10.4417 4.4565 5.3118
KMRC-20 GDSC1; CTRP2 6.9305 14.0341 2.7618 12.0223
VMRC-RCZ GDSC1; CTRP2 6.9831 12.2896 3.6654 8.3056
TUHR10TKB CTRP2 6.9955 8.5392 5.4721 1.0754
VMRC-RCW GDSC1; CTRP2 7.5486 16.2592 2.13 13.3618
RCC10RGB GDSC1; CTRP2 7.6408 12.0877 4.2272 5.0471
ACHN GDSC1; CTRP2 7.7484 13.2664 3.7359 6.8443
Caki-2 CTRP2 7.8285 12.7601 4.0317 5.5644
Caki-1 GDSC1; CTRP2 9.4395 18.3026 2.4612 9.3517
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H716 GDSC1; CTRP2 0.1366 5.0934 -0.1704 40.1527
LoVo GDSC1; CTRP2 3.0366 5.9472 2.788 20.9042
SW1463 GDSC1; CTRP2 3.8791 10.6249 1.7696 22.3271
SNU-C1 GDSC1; CTRP2 3.9587 6.1474 3.7392 14.6666
HT115 GDSC1; CTRP2 3.9933 5.1617 3.9713 13.739
CaR-1 GDSC1 4.0445 8.8146 0.9106 12.6418
GP5d GDSC1 4.2513 6.8895 1.9727 4.5274
SNU-407 CTRP2 4.2555 6.2558 4.0305 12.7136
SW626 GDSC1 4.2739 9.2224 0.876 12.2076
COLO201 CTRP2 4.3615 7.8761 3.5142 14.4012
SW48 GDSC1; CTRP2 4.395 7.3275 3.7835 13.2562
GP2d CTRP2 4.4075 6.8362 3.993 12.4146
CCK-81 GDSC1; CTRP2 4.5463 6.923 4.1072 11.5904
SW620 GDSC1; CTRP2 4.5799 6.6324 4.2543 10.9352
COLO205 GDSC1; CTRP2 4.647 7.3995 4.0155 11.6757
LS513 GDSC1; CTRP2 4.6852 6.5066 4.4133 10.0348
MDST8 GDSC1; CTRP2 4.6887 5.9008 4.6015 9.3337
SNU-61 CTRP2 4.7102 10.1278 2.8066 16.3603
SNU-C2A CTRP2 4.7131 10.7028 2.5302 17.4391
HT-55 GDSC1; CTRP2 4.7325 7.1697 4.2023 10.7151
T84 GDSC1; CTRP2 4.9781 6.7399 4.6377 8.3572
CW-2 GDSC1; CTRP2 5.0013 8.3231 3.9509 11.0431
LS180 GDSC1; CTRP2 5.0292 7.4087 4.4028 9.1477
HT-29 GDSC1; CTRP2 5.1519 7.5097 4.4799 8.5291
COLO 320HSR GDSC1 5.2669 7.7402 2.147 1.7615
LS123 GDSC1; CTRP2 5.3147 10.1365 3.3624 12.7441
LS1034 GDSC1; CTRP2 5.4248 7.9957 4.5141 7.7372
HCT 15 GDSC1; CTRP2 5.5089 13.3502 1.9362 17.9222
SW837 GDSC1 5.79 7.6902 2.3835 0.421
HCC2998 GDSC1 5.981 7.8759 2.3887 0.3347
KM12 GDSC1; CTRP2 6.0295 7.0593 5.5245 2.2145
SNU-C5 CTRP2 6.0592 11.4605 3.3487 11.2664
SK-CO-1 CTRP2 6.0825 8.5827 4.8068 5.1288
SNU-1033 CTRP2 6.2725 9.5535 4.4762 6.1642
HCC-56 CTRP2 6.3066 7.2908 5.6239 1.3209
SNU-C4 CTRP2 6.3485 8.0764 5.2694 2.7158
CL-11 GDSC1; CTRP2 6.4495 8.5961 5.0884 3.3008
SW1417 GDSC1; CTRP2 6.4535 8.8076 4.9872 3.7139
SNU-C2B GDSC1 6.6417 17.4443 -1.459 18.4561
DLD-1 CTRP2 6.6834 9.484 4.8237 4.0214
SW948 GDSC1; CTRP2 6.7079 10.1841 4.4981 5.325
C2BBe1 GDSC1; CTRP2 6.8044 10.397 4.4644 5.3097
NCI-H508 CTRP2 6.9086 9.8573 4.8013 3.7739
COLO 678 GDSC1; CTRP2 6.9119 10.9677 4.263 5.9683
LS411N GDSC1; CTRP2 7.1505 9.8873 4.948 2.8596
RCM-1 [Human ESC] GDSC1; CTRP2 7.1664 9.8985 4.9529 2.8205
HCT 116 GDSC1; CTRP2 7.2795 8.9287 5.455 0.882
OUMS-23 CTRP2 7.4818 9.8018 5.1852 1.6052
RKO GDSC1; CTRP2 7.7328 13.7085 3.5119 7.7551
HCT 8 CTRP2 8.2946 9.6907 5.5948 0.1209
NCI-H747 GDSC1; CTRP2 8.4189 11.0964 5.1159 1.0814
SNU-503 CTRP2 8.4271 9.9688 5.5464 0.1541
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 4.7923 8.0611 1.761 4.85
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HLE GDSC1 0.723 6.0901 -0.6956 35.7983
JHH-7 GDSC1 1.3586 3.5973 1.0162 22.8115
Li-7 CTRP2 1.6466 11.0333 -0.6564 35.712
Hep 3B2.1-7 GDSC1; CTRP2 1.7833 4.9856 1.6345 28.8903
SNU-398 GDSC1 2.073 8.9986 -0.803 29.5576
Huh-7 GDSC1 2.5848 9.4105 -0.5575 26.357
SNU-886 CTRP2 2.7561 11.9902 0.0265 30.7805
Hep-G2/C3A GDSC1 2.7952 5.2538 1.6982 11.0204
HuH-6 CTRP2 2.9954 9.9829 1.1855 46.8202
JHH-1 GDSC1; CTRP2 3.9292 8.1075 2.9681 17.6791
SNU-182 CTRP2 4.1582 8.1014 3.2068 16.1423
JHH-2 GDSC1; CTRP2 4.368 7.3159 3.76 13.4206
SNU-475 GDSC1; CTRP2 4.4998 7.3231 3.8949 12.5401
Hep-G2 CTRP2 4.5418 9.5414 2.927 16.2843
JHH-5 CTRP2 4.6818 6.8713 4.2714 10.5845
PLC/PRF/5 CTRP2 4.7619 8.3079 3.7232 12.5494
SNU-878 CTRP2 5.0858 10.8022 2.826 15.4215
JHH-4 GDSC1; CTRP2 5.164 14.1875 1.2178 21.1909
SNU-449 GDSC1; CTRP2 5.4861 12.8907 2.1455 17.1926
SNU-423 GDSC1; CTRP2 5.4892 11.0938 3.0433 13.6703
HLF CTRP2 6.4561 12.7456 3.0304 11.8093
HuH-1 GDSC1; CTRP2 6.4871 10.6344 4.1071 7.3243
SNU-761 CTRP2 6.5742 11.4701 3.7594 8.6158
JHH-6 GDSC1; CTRP2 6.7441 8.1643 5.4952 1.2562
SNU-387 GDSC1; CTRP2 7.2016 18.6443 0.6809 18.8857
SK-HEP-1 GDSC1; CTRP2 7.7633 13.8311 3.4738 7.8606
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 208 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2369 GDSC1 -0.4947 0.1111 -0.4947 43.6839
NCI-H1703 GDSC1; CTRP2 0.4493 12.3565 -2.4653 42.4213
A-427 GDSC1 0.582 5.6978 -0.6644 36.5116
SBC-3 GDSC1 0.6908 6.0866 -0.7266 36.0996
LK-2 GDSC1 1.0596 2.7883 0.9362 25.0518
NCI-H2731 GDSC1 1.8746 8.4126 -0.6932 29.957
NCI-H3122 GDSC1 2.1341 4.685 1.3596 16.4262
NCI-H2591 GDSC1 2.3877 6.1567 0.8862 18.7422
NCI-H1581 GDSC1; CTRP2 2.6173 8.2878 1.5197 26.6814
NCI-H810 GDSC1; CTRP2 2.7672 5.6437 2.5688 22.5182
LC-2/ad GDSC1 2.8749 10.8184 -1.0139 27.2647
NCI-H2869 GDSC1 2.9215 8.9805 -0.0559 22.4901
LC-1F CTRP2 2.9317 7.9678 1.9806 24.1468
NCI-H1341 CTRP2 3.0571 5.6752 2.8772 20.5231
HCC827 GDSC1; CTRP2 3.099 10.6098 1.0055 26.9895
NCI-H520 GDSC1; CTRP2 3.1623 7.3853 2.4529 21.7578
LXF 289 GDSC1; CTRP2 3.1988 7.299 2.5244 21.3877
Lu-99 CTRP2 3.2077 5.4952 3.0795 19.3386
NCI-H1944 GDSC1; CTRP2 3.2128 8.9544 1.8622 23.7746
HCC44 GDSC1; CTRP2 3.2321 7.3568 2.5383 21.2406
COR-L23 GDSC1 3.2714 5.1884 2.1229 5.9937
NCI-H211 GDSC1; CTRP2 3.2813 5.9796 3.0463 19.2279
Calu-6 GDSC1; CTRP2 3.2948 4.8761 3.264 18.4218
NCI-H510A GDSC1; CTRP2 3.4211 9.4457 1.8582 23.2166
NCI-H358 GDSC1; CTRP2 3.442 8.0272 2.4945 20.8128
NCI-H1155 GDSC1; CTRP2 3.5751 5.8173 3.408 17.0302
HCC15 GDSC1; CTRP2 3.6415 6.193 3.38 16.9286
PC-14 GDSC1; CTRP2 3.6556 7.2427 3.0344 18.1748
NCI-H1993 GDSC1 3.6721 9.2953 0.3934 17.1862
NCI-H1734 GDSC1; CTRP2 3.6856 5.484 3.5986 16.0121
NCI-H69 GDSC1; CTRP2 3.7214 6.5492 3.3554 16.781
COLO 699 CTRP2 3.7303 7.7246 2.9219 18.3956
NCI-H1568 GDSC1; CTRP2 3.7468 7.2071 3.1455 17.4968
NCI-H2405 GDSC1; CTRP2 3.7499 8.3835 2.6637 19.3318
NCI-H2286 CTRP2 3.7734 6.5672 3.4058 16.4421
NCI-H1770 GDSC1 3.8274 6.0191 2.1118 4.5125
Sq-1 CTRP2 3.8416 9.8249 2.1072 21.194
NCI-H3255 GDSC1 3.8567 9.6179 0.3751 16.6997
NCI-H596 GDSC1 3.8641 6.4662 1.9234 5.8158
NCI-H2347 GDSC1 3.9093 8.1819 1.1223 11.5754
NCI-H2373 GDSC1 3.9093 9.2443 0.5995 15.1194
Ms-1 GDSC1 3.9182 6.7361 1.8306 6.3639
SK-MES-1 GDSC1; CTRP2 3.9354 8.3821 2.855 18.1009
NCI-H513 GDSC1 3.9988 8.6198 0.9728 12.3518
NCI-H446 GDSC1; CTRP2 4.0324 7.5301 3.3193 16.0402
Calu-3 GDSC1; CTRP2 4.0653 9.5077 2.476 19.2287
RERF-LC-Sq1 GDSC1 4.0745 7.2649 1.6829 7.0451
SBC-1 GDSC1 4.0984 6.6146 2.0055 4.6384
COR-L105 GDSC1; CTRP2 4.1243 8.7132 2.8995 17.4353
NCI-H647 GDSC1; CTRP2 4.1362 8.4994 3.0079 16.98
NCI-H2795 GDSC1 4.1544 16.7649 -2.9457 29.6213
NCI-H847 GDSC1 4.1564 5.8287 2.3934 1.8826
NCI-H64 GDSC1 4.1859 6.6639 2.0367 4.2202
NCI-H1436 GDSC1 4.1895 6.2064 2.246 2.7753
PaCa-3 GDSC1 4.2158 9.2707 0.8111 12.8076
DV-90 CTRP2 4.2181 6.9002 3.7663 13.8104
HCC2108 CTRP2 4.2361 7.4747 3.5558 14.5711
LB647-SCLC GDSC1 4.2591 6.0065 2.371 1.8562
NCI-H1373 CTRP2 4.261 6.9501 3.793 13.5884
NCI-H345 GDSC1 4.2639 5.2206 2.6864 0.2908
COR-L88 GDSC1 4.2696 11.8406 -0.412 19.8182
NCI-H2106 CTRP2 4.3208 8.1956 3.3313 15.2292
IST-SL2 GDSC1 4.3454 7.1858 1.8937 4.8762
COR-L51 CTRP2 4.3461 7.7271 3.5631 14.2489
SHP-77 GDSC1; CTRP2 4.3489 6.5703 4.0278 12.45
NCI-H2595 GDSC1 4.3621 6.5981 2.1693 2.961
NCI-H82 GDSC1 4.3644 6.7939 2.0833 3.5287
IST-SL1 GDSC1 4.3786 6.7469 2.1124 3.3061
NCI-H2085 GDSC1; CTRP2 4.3797 11.3543 1.9004 20.6088
NCI-H1781 GDSC1 4.3802 8.5731 1.2629 9.2601
NCI-H2804 GDSC1 4.3849 9.4049 0.8654 11.9659
NCI-H2141 GDSC1; CTRP2 4.4106 7.4539 3.7469 13.357
NCI-H1105 CTRP2 4.4164 12.4291 1.4111 22.2519
ChaGo-K-1 GDSC1; CTRP2 4.4425 8.5065 3.3135 14.9892
Lu-135 GDSC1 4.4437 11.3533 -0.0431 17.346
NCI-H1688 GDSC1 4.475 8.3856 1.4149 7.9515
NCI-H1876 GDSC1 4.4975 9.814 0.7458 12.44
NCI-H1048 GDSC1 4.5132 8.8613 1.2142 9.2527
NCI-H1694 GDSC1 4.5221 6.3611 2.3546 1.573
NCI-H290 GDSC1 4.5235 6.6504 2.2336 2.278
NCI-H2227 GDSC1 4.5249 6.3013 2.3805 1.4268
NCI-H2722 GDSC1 4.5252 13.3311 -0.9561 21.6452
NCI-H748 GDSC1 4.5276 6.6683 2.2281 2.3052
EBC-1 GDSC1; CTRP2 4.5367 7.2433 3.9669 12.1597
VMRC-LCD CTRP2 4.5765 7.2088 4.023 11.8339
NCI-H1975 GDSC1 4.5961 12.0222 -0.26 18.0745
UMC-11 GDSC1 4.6107 10.7564 0.3684 14.4894
NCI-H209 GDSC1 4.6114 8.3709 1.5093 6.9644
LK2 CTRP2 4.619 6.1008 4.473 10.0087
NCI-H1755 GDSC1; CTRP2 4.6264 9.1876 3.177 15.0812
NCI-H841 GDSC1; CTRP2 4.6299 9.0048 3.2668 14.712
MOR/CPR CTRP2 4.6303 6.1926 4.4583 10.0287
NCI-H2171 GDSC1 4.6424 6.0755 2.5221 0.632
NCI-H1838 GDSC1; CTRP2 4.6659 7.3796 4.0436 11.5149
NCI-H2196 GDSC1; CTRP2 4.6745 7.5296 3.9874 11.7142
NCI-H2818 GDSC1 4.6823 7.6983 1.8606 4.4017
NCI-H838 GDSC1; CTRP2 4.7084 7.7831 3.9095 11.936
NCI-H524 GDSC1 4.7131 6.6437 2.3306 1.4612
ABC-1 GDSC1 4.7285 7.759 1.8599 4.3162
NCI-H1304 GDSC1 4.7599 13.6918 -0.9596 20.9949
Lu-65 GDSC1; CTRP2 4.7809 9.0181 3.4073 13.781
Lu-165 GDSC1 4.7824 9.3141 1.1761 8.8415
NCI-H727 GDSC1; CTRP2 4.7872 10.5044 2.6962 16.6166
NCI-H1666 GDSC1; CTRP2 4.7883 8.0245 3.8803 11.8511
NCI-H2087 GDSC1; CTRP2 4.8095 8.4665 3.6959 12.543
NCI-H720 GDSC1 4.8135 6.0285 2.6064 0.2554
HCC1588 CTRP2 4.8213 7.2535 4.2586 10.2585
A-549 GDSC1; CTRP2 4.8331 7.3952 4.2091 10.4232
LCLC-103H GDSC1; CTRP2 4.8886 6.9175 4.4709 9.2475
NCI-H1648 GDSC1 4.9001 7.0932 2.2364 1.7325
COLO 668 GDSC1; CTRP2 4.9093 7.4341 4.2697 9.9854
DMS 114 GDSC1; CTRP2 4.9147 8.8671 3.6084 12.6455
RERF-LC-MS GDSC1; CTRP2 4.9288 8.6531 3.724 12.1409
NCI-H1184 CTRP2 4.9335 7.6396 4.2017 10.1954
HARA [Human squamous cell lung carcinoma] GDSC1; CTRP2 4.9542 7.3738 4.3423 9.5808
NCI-H526 GDSC1; CTRP2 4.9572 8.9346 3.6168 12.5107
NCI-H2135 GDSC1 4.9736 6.7583 2.402 0.8568
NCI-H1836 GDSC1 4.9772 6.5144 2.4947 0.5032
NCI-H1915 GDSC1; CTRP2 4.9957 9.2094 3.521 12.812
NCI-H2081 GDSC1; CTRP2 5.0065 8.8652 3.6973 12.0663
NCI-H661 GDSC1; CTRP2 5.008 8.4253 3.909 11.1979
NCI-H2461 GDSC1 5.0321 16.0154 -1.9015 24.0123
CPC-N GDSC1 5.0379 6.7076 2.4477 0.6288
HCC2279 CTRP2 5.0634 9.2624 3.5593 12.4989
NCI-H23 GDSC1; CTRP2 5.0639 8.3412 4.0031 10.6807
DMS 273 GDSC1; CTRP2 5.072 7.3221 4.485 8.71
Lu-139 GDSC1 5.102 12.3642 -0.0672 15.6545
CAL-12T GDSC1; CTRP2 5.13 9.6375 3.4386 12.8418
NCI-H1793 GDSC1 5.1307 6.7571 2.4664 0.506
NCI-H1092 GDSC1; CTRP2 5.1644 7.1143 4.6718 7.7283
NCI-H1435 GDSC1; CTRP2 5.1784 10.6683 2.9763 14.6133
NCI-H2110 GDSC1; CTRP2 5.181 7.4674 4.5284 8.2614
IA-LM GDSC1; CTRP2 5.1827 9.7021 3.4557 12.653
DMS 79 GDSC1; CTRP2 5.1934 6.3779 5.0073 6.3427
HCC33 GDSC1 5.2071 7.1043 2.3686 0.8067
NCI-H2029 GDSC1; CTRP2 5.214 8.591 4.0267 10.2314
NCI-H1437 GDSC1 5.2239 11.5383 0.4117 12.6152
NCI-H1963 GDSC1 5.2523 6.874 2.4712 0.4263
SK-LU-1 GDSC1; CTRP2 5.2921 10.3015 3.2604 13.2108
DMS 53 GDSC1; CTRP2 5.3331 10.1893 3.353 12.7423
NCI-H1299 GDSC1; CTRP2 5.3422 9.0658 3.9148 10.4033
NCI-H1573 GDSC1; CTRP2 5.3843 9.8938 3.5452 11.84
NCI-H650 GDSC1; CTRP2 5.4055 10.9845 3.0236 13.928
COR-L95 GDSC1; CTRP2 5.4126 6.8997 5.0199 5.7042
SW1573 GDSC1 5.5455 7.8015 2.2462 1.0325
HCC366 CTRP2 5.5711 9.0175 4.147 8.9375
NCI-H2228 GDSC1; CTRP2 5.6234 9.7729 3.8186 10.1956
NCI-H1563 GDSC1; CTRP2 5.6277 8.003 4.6993 6.5131
KNS-62 CTRP2 5.646 10.456 3.4984 11.478
LUDLU-1 CTRP2 5.6812 8.9114 4.298 8.0729
HCC4006 CTRP2 5.6948 7.3118 5.1001 4.6999
NCI-H1395 CTRP2 5.8889 8.9686 4.4508 7.0046
NCI-H2803 GDSC1 5.8926 17.5196 -2.0132 22.2641
NCI-H1792 GDSC1; CTRP2 5.9253 9.2472 4.3427 7.3854
NCI-H1650 GDSC1; CTRP2 5.9399 13.2006 2.3788 15.3699
LC-1/sq-SF CTRP2 5.9401 8.7203 4.6185 6.1979
NCI-H522 GDSC1; CTRP2 5.9972 12.3136 2.8704 13.328
T3M-10 CTRP2 6.0174 7.4819 5.303 3.1689
SBC-5 GDSC1; CTRP2 6.019 6.7695 5.6605 1.6632
NCI-H2009 GDSC1; CTRP2 6.0207 10.0467 4.0234 8.5373
NCI-H2172 GDSC1; CTRP2 6.0448 9.5932 4.2703 7.4554
NCI-H322M GDSC1 6.1121 8.1036 2.3573 0.3597
NCI-H187 GDSC1 6.1557 14.4793 -0.371 14.6657
HCC95 CTRP2 6.172 8.8356 4.7536 5.1842
NCI-H2023 GDSC1; CTRP2 6.1845 8.9474 4.7079 5.3531
NCI-H2291 GDSC1; CTRP2 6.1883 8.2741 5.0471 3.9224
Lu-99A GDSC1 6.2052 18.0462 -2.0483 21.6605
NCI-H226 GDSC1; CTRP2 6.2291 11.6702 3.3839 10.7958
LC-1/sq GDSC1 6.2711 8.5765 2.2498 0.5678
NCI-H889 CTRP2 6.3025 8.5925 4.9785 4.0065
EPLC-272H GDSC1; CTRP2 6.3218 13.0496 2.7702 13.0987
NCI-H2030 GDSC1; CTRP2 6.3912 11.0551 3.8219 8.6836
NCI-H2122 GDSC1; CTRP2 6.4828 12.6936 3.0777 11.5697
NCI-H1339 CTRP2 6.5326 11.7266 3.5992 9.3513
HCC78 GDSC1; CTRP2 6.5516 12.6492 3.1546 11.1339
NCI-H460 GDSC1; CTRP2 6.5657 9.0486 4.9515 3.68
NCI-H1693 GDSC1; CTRP2 6.5705 13.0601 2.9647 11.8627
NCI-H1623 GDSC1; CTRP2 6.6104 9.8257 4.6022 5.053
NCI-H2126 CTRP2 6.6441 10.7092 4.191 6.7044
NCI-H2444 GDSC1; CTRP2 6.6726 9.7323 4.6941 4.572
SW1271 GDSC1; CTRP2 6.69 16.2031 1.4925 17.1576
NCI-H1869 GDSC1; CTRP2 6.705 10.51 4.3354 6.0036
LCLC-97TM1 GDSC1; CTRP2 6.7176 8.8845 5.1386 2.6872
EKVX GDSC1; CTRP2 6.9348 10.2649 4.6223 4.4621
RERF-LC-Ad1 CTRP2 6.9931 8.3727 5.5434 0.8344
NCI-H292 GDSC1; CTRP2 6.9988 9.699 4.9382 3.0979
HCC1833 CTRP2 7.0208 17.9288 0.8951 18.5365
RERF-LC-KJ GDSC1 7.0698 18.0212 -1.4499 17.5034
NCI-H1651 GDSC1; CTRP2 7.1264 13.0441 3.4003 9.1469
RERF-LC-Ad2 CTRP2 7.2324 11.5536 4.206 5.71
HCC1195 CTRP2 7.2448 11.3529 4.3117 5.264
RERF-LC-A1 CTRP2 7.2526 12.4344 3.7918 7.3596
HCC1438 CTRP2 7.2546 9.1872 5.3301 1.3196
HOP-92 GDSC1; CTRP2 7.2886 13.2444 3.4213 8.7992
NCI-H322 CTRP2 7.3795 11.5504 4.3089 5.0825
BEN GDSC1; CTRP2 7.4196 9.5271 5.2715 1.3664
NCI-H1355 GDSC1; CTRP2 7.5021 11.1482 4.581 3.8402
HCC1171 CTRP2 7.5366 13.5422 3.4546 8.2778
Lu-134-A GDSC1 7.5607 16.3285 -0.3563 11.7087
NCI-H441 GDSC1; CTRP2 7.6324 12.9607 3.8035 6.7422
Calu-1 CTRP2 7.7321 9.8435 5.2987 1.0199
NCI-H2170 GDSC1; CTRP2 7.9085 15.8242 2.6075 11.0005
NCI-H2342 GDSC1; CTRP2 7.9257 18.4066 1.3525 15.4666
LOU-NH91 GDSC1; CTRP2 7.9275 15.1935 2.9284 9.7464
HOP-62 GDSC1; CTRP2 7.9891 12.1299 4.4291 3.825
HCC2935 CTRP2 8.235 9.7873 5.539 0.2073
NCI-H196 GDSC1; CTRP2 9.0595 17.6732 2.5101 9.6832
Hs 888.Lu CTRP2 5.7663 10.2936 3.6838 10.462
⏷ Show the Full List of 208 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 4.4944 8.7058 1.2758 8.8748
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -0.8483 8.5834 -2.2972 47.1322
A2780 GDSC1; CTRP2 2.7286 6.4338 2.3124 23.551
OV7 CTRP2 3.5203 13.7113 -0.0529 28.931
COV434 CTRP2 3.5512 5.6403 3.4222 17.0543
ES-2 GDSC1 3.9191 6.9896 1.7095 7.2619
OVCAR-3 GDSC1 4.182 11.5289 -0.3239 19.6333
Caov-4 GDSC1 4.205 8.4299 1.2119 10.0903
DOV13 CTRP2 4.2879 6.36 4.0328 12.6089
HEY A8 CTRP2 4.4333 7.8754 3.5882 13.9218
ONCO-DG-1 CTRP2 4.454 11.2741 2.0093 20.0302
SK-OV-3 GDSC1; CTRP2 4.4875 10.6057 2.3646 18.6131
IGROV-1 GDSC1; CTRP2 4.5521 9.8492 2.7901 16.8019
OVTOKO GDSC1; CTRP2 4.6153 7.8553 3.7827 12.6796
OVSAHO CTRP2 4.6788 5.9326 4.583 9.4303
Caov-3 GDSC1; CTRP2 4.7548 7.7605 3.9667 11.5892
MCAS CTRP2 5.1679 10.2395 3.178 13.8205
TOV-21G GDSC1 5.1905 6.5846 2.5502 0.2473
SNU-119 CTRP2 5.2059 10.4103 3.1285 13.9373
ES2 CTRP2 5.3261 8.863 3.9994 10.0894
OV-90 GDSC1; CTRP2 5.3911 9.9917 3.503 11.9992
RMG-I GDSC1; CTRP2 5.4341 8.4779 4.2879 8.652
EFO-21 GDSC1; CTRP2 5.5814 9.3123 4.0101 9.4863
OVKATE GDSC1 5.6867 7.5147 2.407 0.4037
OVK18 CTRP2 5.7312 7.8621 4.8629 5.6058
JHOC-5 CTRP2 5.7823 8.1498 4.766 5.9019
SNU-840 CTRP2 5.9398 11.1533 3.4022 11.28
TYK-nu GDSC1; CTRP2 6.1584 10.338 3.9918 8.4058
SNU-8 CTRP2 6.1701 8.1266 5.1061 3.7081
COV644 CTRP2 6.2098 10.0631 4.1711 7.5585
JHOM-1 CTRP2 6.2193 11.0304 3.6956 9.5262
Kuramochi GDSC1; CTRP2 6.2288 10.8755 3.7808 9.1542
OAW42 GDSC1; CTRP2 6.2512 7.935 5.2654 2.8962
FU-OV-1 GDSC1; CTRP2 6.3444 9.0678 4.7749 4.7845
OAW28 GDSC1; CTRP2 6.3972 14.2905 2.2115 15.1127
EFO-27 GDSC1; CTRP2 6.4482 10.1548 4.3152 6.5242
OV56 CTRP2 6.468 8.8396 4.9822 3.7109
OVCAR-8 GDSC1; CTRP2 6.8056 11.6817 3.8323 7.9165
OVCAR-4 GDSC1; CTRP2 6.9934 13.3093 3.1693 10.2983
OVISE GDSC1; CTRP2 7.0557 9.6345 5.006 2.7551
COV362 CTRP2 7.3591 13.6751 3.2615 9.326
OVCAR-5 GDSC1; CTRP2 7.5202 11.4987 4.4274 4.4191
OC 314 GDSC1; CTRP2 7.7325 9.1381 5.5785 0.2942
TOV-112D GDSC1; CTRP2 7.8864 15.3604 2.818 10.2336
JHOS-2 CTRP2 9.1834 18.0189 2.4277 9.8118
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 4.4195 11.7604 1.7404 21.0913
H-STS CTRP2 4.7766 11.4605 2.2188 18.4871
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 4.605 9.7416 2.8923 16.2701
Aska-SS CTRP2 4.6261 6.6344 4.3031 10.6194
A-204 GDSC1; CTRP2 -1.9906 4.4875 -2.3537 53.0146
STS-0421 GDSC1 -0.688 2.6299 -0.9301 46.6177
G-402 GDSC1; CTRP2 -0.4239 8.1707 -1.6914 44.8744
G-401 GDSC1; CTRP2 2.0836 6.5032 1.5884 28.0832
TTC-709 CTRP2 2.5401 9.5236 0.9215 28.8574
VA-ES-BJ GDSC1 2.843 10.8796 -1.0714 27.6176
Rh41 GDSC1; CTRP2 3.0064 7.2575 2.3334 22.6489
SW684 GDSC1 3.0855 12.284 -1.5709 28.6574
MFH-ino GDSC1 3.6021 8.5064 0.7311 15.2435
GCT GDSC1; CTRP2 4.0684 6.9766 3.5771 14.9516
Hs 633.T GDSC1 4.1674 6.5082 2.0969 3.838
Rh30 GDSC1 4.2819 12.3044 -0.6318 20.8656
EW-8 GDSC1 4.3487 8.0345 1.4985 7.6758
BT-12 CTRP2 4.3945 6.6707 4.041 12.2694
TE 441.T GDSC1 4.6636 5.7885 2.6353 0.2435
SW872 GDSC1 4.6638 7.1417 2.0962 2.9005
MES-SA GDSC1; CTRP2 4.7041 8.6404 3.5109 13.5479
BT-16 CTRP2 4.987 6.2121 4.8406 7.5642
SK-UT-1 GDSC1; CTRP2 5.165 9.2913 3.6403 11.9348
Tm87-16 CTRP2 5.3798 12.4331 2.2806 16.9081
TE 617.T CTRP2 5.4577 7.6314 4.7212 6.8086
SK-LMS-1 GDSC1; CTRP2 5.7644 9.7289 3.9639 9.2973
RKN GDSC1; CTRP2 5.8751 10.5358 3.6561 10.3575
KYM-1 GDSC1; CTRP2 6.0044 9.0984 4.4839 6.6366
HT-1080 GDSC1; CTRP2 6.5251 12.8315 3.0427 11.6332
RD GDSC1; CTRP2 6.6366 16.3656 1.3686 17.6829
SW982 GDSC1; CTRP2 6.6612 18.2529 0.4462 20.5954
Hs 729.T CTRP2 6.9538 13.3029 3.1424 10.474
Rh18 CTRP2 8.1934 14.1908 3.5929 6.7861
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 7.8924 9.9063 5.35 0.8818
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; CTRP2 3.2651 6.0424 3.0118 19.4012
MPP 89 GDSC1; CTRP2 3.2895 8.2732 2.2325 22.2131
NCI-H2452 GDSC1; CTRP2 4.6827 11.8869 1.923 19.8068
NCI-H28 GDSC1; CTRP2 4.8788 6.5148 4.6188 8.7068
NCI-H2052 GDSC1; CTRP2 5.6698 9.095 4.1966 8.5206
ACC-MESO-1 CTRP2 5.962 9.6231 4.1859 7.971
JL-1 CTRP2 6.0439 7.7425 5.1949 3.5716
IST-Mes1 GDSC1; CTRP2 6.2037 12.8927 2.752 13.396
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1; CTRP2 3.41 7.7424 2.5769 20.592
22Rv1 GDSC1; CTRP2 4.5724 8.4494 3.4695 14.0399
PC-3 GDSC1 5.4043 7.8997 2.1464 1.6122
VCaP GDSC1; CTRP2 6.7181 10.6185 4.2917 6.163
DU145 GDSC1; CTRP2 6.8112 12.5784 3.3923 9.7097
PaCa-3 CTRP2 6.8157 10.9371 4.2073 6.3523
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 4.1324 5.9394 3.9855 13.2493
A-253 GDSC1; CTRP2 6.139 14.0294 2.1304 15.9162
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 0.3407 5.6417 -0.8882 38.7612
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Fu97 GDSC1 -0.4449 2.381 -0.6104 43.67
SNU-16 GDSC1; CTRP2 0.9113 5.8129 0.504 35.4393
LMSU CTRP2 2.2936 9.5818 0.6414 30.4409
NCC-StC-K140 CTRP2 2.5191 7.4294 1.7466 26.1935
HSC-39 GDSC1 2.6053 6.3715 0.975 17.2079
HGC-27 GDSC1; CTRP2 2.6441 5.3916 2.4892 23.1846
GSS CTRP2 2.977 5.1915 2.8852 20.7482
ECC10 GDSC1; CTRP2 3.4814 5.9554 3.2712 17.8077
SCH GDSC1 3.5893 5.6644 2.1212 5.0639
OCUM-1 GDSC1; CTRP2 3.6578 10.2745 1.7164 23.0905
SNU-1 GDSC1; CTRP2 3.6812 6.2306 3.4123 16.6913
SNU-620 CTRP2 3.6939 5.1101 3.6611 15.7699
KATO III CTRP2 3.8387 14.5526 -0.1635 28.4187
SNU-5 GDSC1; CTRP2 4.1394 6.1312 3.9411 13.3881
SNU-668 CTRP2 4.241 5.8495 4.1259 12.4131
NCI-N87 GDSC1; CTRP2 4.339 6.6183 4.0001 12.5823
MKN28 GDSC1 4.4069 7.7049 1.6912 6.1654
RF-48 GDSC1 4.4932 7.1236 2.0095 3.7739
23132/87 GDSC1; CTRP2 4.7857 7.706 4.0225 11.2877
TMK-1 GDSC1 4.8194 10.2702 0.7466 11.576
NUGC-3 GDSC1; CTRP2 4.8444 9.9421 3.0232 15.1821
MKN1 GDSC1; CTRP2 5.0529 9.066 3.6445 12.1739
TGBC11TKB GDSC1 5.1591 7.3265 2.2625 1.3093
SNU-719 CTRP2 5.2624 7.5696 4.5613 7.9282
HuG1-N CTRP2 5.3248 10.1829 3.3486 12.7785
SNU-216 CTRP2 5.3941 7.607 4.6718 7.161
KE-39 CTRP2 5.4381 8.8856 4.0915 9.4581
SH-10-TC CTRP2 5.5215 8.6136 4.3016 8.4012
AGS GDSC1; CTRP2 5.5693 9.6424 3.8356 10.2393
IM95 GDSC1; CTRP2 5.6345 14.3794 1.5305 19.1114
SNU-601 CTRP2 5.6415 8.2075 4.6111 6.85
RERF-GC-1B GDSC1 5.7972 8.1791 2.2083 0.9887
GCIY GDSC1 6.0016 15.3211 -0.8742 17.4204
MKN7 GDSC1; CTRP2 6.2825 10.4234 4.05 7.9308
Hs 746.T CTRP2 6.4209 10.6304 4.0571 7.6502
GSU CTRP2 6.667 8.3432 5.3632 1.861
MKN45 GDSC1; CTRP2 6.7061 8.4419 5.3421 1.8924
ECC12 CTRP2 6.7165 8.7593 5.1979 2.4507
NUGC-4 GDSC1; CTRP2 7.6407 10.995 4.7391 3.0631
MKN74 CTRP2 8.402 15.4976 3.1089 8.3626
SNU-1077 CTRP2 2.9981 6.1955 2.6775 21.4189
SNU-685 CTRP2 5.6128 9.9447 3.7239 10.6121
SNG-M GDSC1; CTRP2 5.9437 10.4828 3.7407 9.869
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 -1.2606 5.3727 -1.7548 48.8718
CGTH-W-1 GDSC1; CTRP2 -0.4744 4.3568 -0.6903 43.861
TT2609-C02 GDSC1; CTRP2 1.6477 6.3726 1.1527 30.9323
ASH-3 GDSC1 3.3905 16.9972 -3.6759 33.4881
IHH-4 GDSC1 3.4063 5.7867 1.9291 7.0779
KMH-2 GDSC1 3.549 9.2982 0.296 18.1956
ML-1 [Human leukemia] GDSC1; CTRP2 3.8651 13.3661 0.4396 26.6872
K5 GDSC1 4.3193 6.5696 2.1578 3.1168
HTC-C3 GDSC1 4.6514 7.4271 1.9641 3.774
WRO GDSC1 4.6697 14.4372 -1.3937 23.0767
BHT-101 GDSC1; CTRP2 4.813 6.5855 4.5219 9.2606
8305C GDSC1; CTRP2 4.8172 7.6665 4.0721 11.0093
TT GDSC1; CTRP2 5.3572 11.1037 2.9215 14.4433
FTC-238 CTRP2 5.6461 8.1676 4.635 6.7404
8505C GDSC1; CTRP2 6.0973 9.9394 4.1407 7.8981
FTC-133 GDSC1; CTRP2 6.2974 10.8997 3.8242 8.8457
CAL-62 GDSC1; CTRP2 6.2978 9.3326 4.6064 5.5727
B-CPAP GDSC1; CTRP2 6.8709 11.6043 3.9196 7.448
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-8 CTRP2 2.3083 6.0982 1.9523 26.1206
JHU-011 GDSC1 2.6856 5.6678 1.3958 13.7799
BICR 10 GDSC1 3.1989 8.0928 0.6174 17.3897
OSC-20 GDSC1 3.3124 7.9114 0.7995 15.7673
HO-1-u-1 GDSC1 3.5097 6.7418 1.535 9.7779
HO-1-N-1 GDSC1 3.5408 5.5563 2.1397 5.058
JHU-029 GDSC1 3.6876 7.1031 1.4895 9.57
YD-10B CTRP2 3.9903 5.8378 3.8555 14.1518
SAS GDSC1 4.0067 10.4282 0.0879 17.9306
Detroit 562 GDSC1; CTRP2 4.0341 6.0175 3.8578 14.0085
BB30-HNC GDSC1 4.0812 9.3217 0.6887 14.0116
SNU-899 CTRP2 4.0966 7.6908 3.3196 15.8653
PCI-15A GDSC1 4.2111 7.9499 1.4471 8.399
BICR 18 CTRP2 4.3691 11.2498 1.941 20.486
SNU-46 CTRP2 4.4474 8.1232 3.4923 14.2654
SCC-15 GDSC1 4.4765 12.6961 -0.6793 20.5161
SNU-1214 CTRP2 4.5726 8.4762 3.4572 14.0887
KON GDSC1 4.7425 9.6767 0.9783 10.2641
LB771-HNC GDSC1 4.7842 12.1761 -0.1995 17.2248
BHY GDSC1; CTRP2 4.8005 7.8478 3.9733 11.447
SAT [Human HNSCC] GDSC1 4.8769 8.3925 1.6608 5.3502
Ca9-22 GDSC1 4.9441 8.8992 1.47 6.4886
HSC-3 GDSC1; CTRP2 4.9488 7.9308 4.0833 10.6337
PCI-30 GDSC1 4.9492 7.0292 2.2853 1.4205
PCI-38 GDSC1 4.9494 6.7057 2.4118 0.836
HSC-2 GDSC1; CTRP2 4.979 8.445 3.8715 11.4201
SNU-1076 CTRP2 5.1354 7.9646 4.2511 9.4977
NCI-H3118 GDSC1 5.1677 7.2353 2.3019 1.1197
BICR 22 GDSC1; CTRP2 5.2698 6.854 4.8944 6.5719
UPCI-SCC-090 GDSC1 5.3128 11.6613 0.4119 12.3942
OSC-19 GDSC1 5.3597 7.3077 2.355 0.7481
PE/CA-PJ34 (clone C12) CTRP2 5.3696 10.0253 3.4669 12.1947
PE/CA-PJ15 GDSC1; CTRP2 5.4013 8.2992 4.3447 8.4908
PCI-04B GDSC1 5.4284 7.5721 2.2841 0.9721
CAL-27 GDSC1; CTRP2 5.6155 6.9851 5.1819 4.5481
BB49-HNC GDSC1 5.6634 19.1699 -2.987 25.917
JHU-022 GDSC1 5.7021 7.7254 2.3376 0.5962
SKN-3 GDSC1 5.8062 18.5219 -2.5647 24.3132
PE/CA-PJ49 CTRP2 5.8749 7.47 5.1858 3.9499
BICR 78 GDSC1 5.9105 7.6594 2.4381 0.2537
DOK GDSC1 5.9482 14.9936 -0.7534 16.9922
SNU-1041 CTRP2 6.0021 9.9964 4.033 8.5332
PCI-06A GDSC1 6.1863 8.0177 2.4132 0.2253
KOSC-2 GDSC1 6.3384 8.2837 2.3762 0.252
SCC-4 GDSC1; CTRP2 6.5911 8.2147 5.3741 1.9207
SCC-25 GDSC1; CTRP2 6.6396 10.241 4.4191 5.7647
SCC-9 GDSC1; CTRP2 6.9882 13.4646 3.0885 10.6305
CAL-33 GDSC1; CTRP2 7.1679 11.1763 4.3437 5.2473
FaDu GDSC1; CTRP2 7.287 14.2647 2.9182 10.8018
BICR 6 CTRP2 7.4262 12.2823 3.9884 6.3023
BICR 16 CTRP2 7.4896 10.9701 4.6566 3.5625
SNU-1066 CTRP2 7.5255 10.45 4.9193 2.5197
HSC-4 GDSC1; CTRP2 7.7139 14.2775 3.2226 8.9258
BICR 56 CTRP2 8.4007 9.8331 5.5838 0.1154
BICR 31 GDSC1; CTRP2 8.882 19.2183 1.6463 12.9778
PE/CA-PJ41 (clone D2) CTRP2 10.6594 20.5363 2.188 8.7905
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JMSU-1 CTRP2 0.6832 3.6638 0.632 35.8818
UM-UC-1 CTRP2 0.846 7.8174 -0.1956 37.4471
RT-112 GDSC1; CTRP2 0.871 4.9172 0.6615 35.1252
253J CTRP2 1.4755 4.3496 1.3982 30.6968
5637 GDSC1; CTRP2 4.4219 9.5939 2.7858 17.1347
BFTC-905 GDSC1 4.427 7.3468 1.8693 4.8686
J82 GDSC1; CTRP2 4.4767 11.0364 2.146 19.4673
RT-4 GDSC1; CTRP2 4.5584 9.7663 2.8357 16.6064
VM-CUB-1 CTRP2 4.6986 7.7071 3.9336 11.8652
U-BLC1 CTRP2 4.9494 8.3874 3.87 11.4973
SW780 GDSC1 5.4687 9.0096 1.7176 3.9112
SW1710 GDSC1; CTRP2 5.6587 11.266 3.1056 13.063
HT-1197 GDSC1; CTRP2 5.8129 10.983 3.3796 11.6267
TCCSUP GDSC1; CTRP2 5.8719 9.5201 4.1608 8.2552
253J-BV CTRP2 5.8744 8.2611 4.7914 5.6045
T24 GDSC1; CTRP2 5.9586 12.3751 2.8073 13.6563
KU-19-19 GDSC1; CTRP2 6.0131 9.6444 4.2182 7.7355
BC-3C CTRP2 6.0294 10.5539 3.7772 9.5495
639V GDSC1; CTRP2 6.0336 8.2777 4.9188 4.7523
UM-UC-3 GDSC1; CTRP2 6.1003 12.2902 2.9679 12.735
CAL-29 GDSC1; CTRP2 6.1018 7.7032 5.2623 3.1783
647V GDSC1; CTRP2 6.1363 8.0985 5.0929 3.8255
SCaBER CTRP2 6.1487 10.2619 4.0219 8.298
HT-1376 GDSC1; CTRP2 6.235 9.9793 4.2334 7.2509
KMBC-2 CTRP2 7.4916 10.7026 4.7825 3.0754
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB831-BLC GDSC1 0.9608 7.2252 -0.9841 35.5265
KGN GDSC1 1.9159 8.928 -0.9097 30.6742
SKN GDSC1 1.9961 7.5221 -0.1439 26.7981
BPH-1 GDSC1 2.434 5.0137 1.4898 14.1056
JEG-3 GDSC1 2.8619 3.7273 2.5157 4.3507
NT2-D1 GDSC1 3.2467 11.388 -0.9903 25.8378
DoTc2 4510 GDSC1 3.4968 9.3693 0.2193 18.8337
NEC8 GDSC1 3.6302 7.8957 1.0555 12.9168
HEC-1 GDSC1 3.8782 6.7993 1.7731 6.8997
SW962 GDSC1 4.0711 13.0077 -1.1417 23.794
SKG-IIIa GDSC1 4.1176 6.0186 2.2889 2.6252
NCC-IT GDSC1 4.1305 6.9197 1.8832 5.4447
SW954 GDSC1 4.176 11.7759 -0.4505 20.297
PA-1 GDSC1 4.1797 5.9113 2.3702 1.9893
ME-180 GDSC1 4.1895 6.5585 2.0872 3.8588
DSH1 GDSC1 4.2784 8.5967 1.1821 10.0975
JAR GDSC1 4.4722 11.1903 0.0575 16.7
MS751 GDSC1 4.4844 7.7254 1.73 5.7149
C-33 A GDSC1 4.5126 12.0292 -0.3244 18.651
SiHa GDSC1 4.6256 10.5612 0.4735 13.8077
OVMIU GDSC1 4.9655 7.7458 1.9957 3.0294
OMC-1 [Human cervical carcinoma] GDSC1 5.132 7.1054 2.3366 0.9996
SiSo GDSC1 5.1675 10.8454 0.7032 10.9786
C-4-I GDSC1 5.1807 6.8539 2.4507 0.5283
SW756 GDSC1 5.2476 11.4506 0.469 12.2144
HeLa GDSC1; CTRP2 5.3338 6.3536 5.1669 5.3397
Ca Ski GDSC1 5.3591 10.5395 0.9679 8.866
HT-3 GDSC1 5.768 7.5068 2.4396 0.2949
CAL-39 GDSC1 5.8058 7.5391 2.4421 0.2773
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug

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