Details of the Drug

General Information of Drug (ID: DMF98Q0)

Drug Name
Momelotinib
Synonyms
Cyt387; 1056634-68-4; MOMELOTINIB; Cyt-387; N-(Cyanomethyl)-4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)benzamide; CYT 387; CYT 11387; UNII-6O01GMS00P; N-(cyanomethyl)-4-(2-(4-morpholinophenylamino)pyrimidin-4-yl)benzamide; 6O01GMS00P; CHEMBL1078178; AK102858; N-(cyanomethyl)-4-(2-((4-(4-morpholinyl)phenyl)amino)-4-pyrimidinyl)benzamide; N-(cyanomethyl)-4-(2-{[4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)benzamide; CYT387 sulfate salt; N-(Cyanomethyl)-4-(2-((4-morpholinophenyl)-amino)pyrimidin-4-yl)benzamide
Indication
Disease Entry ICD 11 Status REF
Myelofibrosis 2A20.2 Approved [1]
Polycythemia vera 2A20.4 Phase 2 [2]
Thrombocythemia 3B63 Phase 2 [2]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 414.5
Logarithm of the Partition Coefficient (xlogp) 2.6
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C23H22N6O2
IUPAC Name
N-(cyanomethyl)-4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]benzamide
Canonical SMILES
C1COCCN1C2=CC=C(C=C2)NC3=NC=CC(=N3)C4=CC=C(C=C4)C(=O)NCC#N
InChI
InChI=1S/C23H22N6O2/c24-10-12-25-22(30)18-3-1-17(2-4-18)21-9-11-26-23(28-21)27-19-5-7-20(8-6-19)29-13-15-31-16-14-29/h1-9,11H,12-16H2,(H,25,30)(H,26,27,28)
InChIKey
ZVHNDZWQTBEVRY-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
25062766
ChEBI ID
CHEBI:91407
CAS Number
1056634-68-4
UNII
6O01GMS00P
DrugBank ID
DB11763
TTD ID
D0D5ZJ
INTEDE ID
DR1880
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Janus kinase 1 (JAK-1) TT6DM01 JAK1_HUMAN Modulator [1]
Janus kinase 2 (JAK-2) TTRMX3V JAK2_HUMAN Modulator [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [4]
Cytochrome P450 2C9 (CYP2C9) DE5IED8 CP2C9_HUMAN Substrate [4]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Substrate [4]
Cytochrome P450 1A2 (CYP1A2) DEJGDUW CP1A2_HUMAN Substrate [4]
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Substrate [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [5]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [5]
Apoptotic protease-activating factor 1 (APAF1) OTJWIVY0 APAF_HUMAN Gene/Protein Processing [5]
Bcl2-associated agonist of cell death (BAD) OT63ERYM BAD_HUMAN Gene/Protein Processing [5]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Protein Interaction/Cellular Processes [5]
Eukaryotic translation initiation factor 4E (EIF4E) OTDAWNLA IF4E_HUMAN Gene/Protein Processing [5]
Eukaryotic translation initiation factor 4E-binding protein 3 (EIF4EBP3) OTYY2WS5 4EBP3_HUMAN Gene/Protein Processing [5]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Gene/Protein Processing [5]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Post-Translational Modifications [5]
Ribosomal protein S6 kinase beta-1 (RPS6KB1) OTAELNGX KS6B1_HUMAN Gene/Protein Processing [5]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Myelofibrosis
ICD Disease Classification 2A20.2
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Janus kinase 2 (JAK-2) DTT JAK2 2.46E-01 -0.41 -0.6
Cytochrome P450 2C8 (CYP2C8) DME CYP2C8 6.03E-01 7.61E-02 6.10E-01
Cytochrome P450 1A2 (CYP1A2) DME CYP1A2 1.93E-01 3.11E-01 8.10E-01
Mephenytoin 4-hydroxylase (CYP2C19) DME CYP2C19 1.67E-02 8.33E-01 1.75E+00
Cytochrome P450 2C9 (CYP2C9) DME CYP2C9 1.21E-01 5.16E-01 1.33E+00
Cytochrome P450 3A4 (CYP3A4) DME CYP3A4 1.23E-01 4.92E-01 1.13E+00
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 133 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 0.6153 4.6551 0.4328 36.7259
MEC1 CTRP2 1.8385 3.565 1.8311 28.0449
JM1 CTRP2 0.9471 3.6315 0.91 34.0811
MV4-11 CTRP2 -2.92 2.6151 -3.0596 58.7362
EoL-1 CTRP2 -2.6099 0.0292 -2.6117 57.6222
JVM-2 CTRP2 -2.4641 7.6031 -3.7093 54.4995
Pfeiffer CTRP2 -1.4553 2.0667 -1.4848 49.9649
SET-2 CTRP2 -1.0671 3.1015 -1.1544 47.477
F-36P CTRP2 -0.536 5.4397 -0.9813 44.5847
OCI-AML-5 CTRP2 -0.2938 2.9748 -0.3352 42.3356
M-07e CTRP2 -0.2288 4.7111 -0.4892 42.381
HH [Human lymphoma] CTRP2 -0.1349 4.7454 -0.3942 41.7809
MOLM-16 CTRP2 0.0259 4.109 -0.1144 40.4748
Ri-1 CTRP2 0.0758 4.7678 -0.1704 40.4028
KE-97 CTRP2 0.1542 5.869 -0.3367 40.4416
NALM-6 CTRP2 0.3668 4.0409 0.2583 38.1501
SEM CTRP2 0.386 3.8001 0.3066 37.9395
Mino CTRP2 0.3911 3.72 0.3202 37.8812
Hs 611.T CTRP2 0.4607 4.5652 0.2816 37.7304
JJN-3 CTRP2 0.5001 3.8487 0.4219 37.1804
NU-DUL-1 CTRP2 0.6515 2.5116 0.6486 35.9379
Mono-Mac-1 CTRP2 0.6829 5.0818 0.4252 36.4978
Kasumi-2 CTRP2 0.8118 4.7224 0.6329 35.4225
MOTN-1 CTRP2 0.84 4.4517 0.707 35.0964
P31/FUJ CTRP2 0.8853 4.0316 0.8093 34.6173
JVM-3 CTRP2 0.9312 3.681 0.8898 34.2007
Kasumi-1 CTRP2 0.9832 3.4589 0.9582 33.801
AML-193 CTRP2 1.0556 3.7681 1.013 33.3767
L-540 CTRP2 1.0581 3.2908 1.0432 33.2687
Ku812 CTRP2 1.0653 10.7313 -1.1241 38.5089
SU-DHL-6 CTRP2 1.0727 3.9023 1.0196 33.2972
MOLT-16 CTRP2 1.2649 2.9101 1.2624 31.85
OCI-Ly3 CTRP2 1.2831 3.7899 1.2485 31.8358
GA-10 CTRP2 1.3011 2.8442 1.2995 31.6059
697 CTRP2 1.3123 3.1675 1.3061 31.5466
EB1 CTRP2 1.3321 4.1758 1.2659 31.6142
DND-41 CTRP2 1.3572 4.1007 1.3001 31.417
DB CTRP2 1.3828 3.2205 1.3765 31.0772
Ki-JK CTRP2 1.4062 5.729 1.0651 32.0185
U266B1 CTRP2 1.4408 5.6524 1.1218 31.7206
KMS-26 CTRP2 1.445 4.9253 1.2802 31.1904
KMS-12-BM CTRP2 1.4802 3.9092 1.4451 30.5245
RS4;11 CTRP2 1.4811 4.5687 1.2745 26.1921
OCI-M1 CTRP2 1.4972 2.7423 1.4968 30.2953
WSU-DLCL2 CTRP2 1.5119 2.4712 1.5119 30.1959
EHEB CTRP2 1.5122 5.5871 1.2152 31.1796
HDLM-2 CTRP2 1.5591 5.057 1.3794 30.4831
RCH-ACV CTRP2 1.5831 4.8406 1.4436 30.1896
Jurkat CTRP2 1.6249 5.8617 1.2699 30.6274
OCI-AML-3 CTRP2 1.6284 2.831 1.6281 29.4212
ST486 CTRP2 1.727 2.4756 1.727 28.7633
SUP-M2 CTRP2 1.7285 2.4864 1.7285 28.7533
L-428 CTRP2 1.7363 4.7554 1.6218 29.0867
Daudi CTRP2 1.7458 3.2085 1.7438 28.6446
A3/Kawakami CTRP2 1.7493 2.5814 1.7493 28.6142
KM-H2 CTRP2 1.7576 6.4377 1.253 30.2473
RPMI-8402 CTRP2 1.7646 3.7855 1.7472 28.5706
TF-1 CTRP2 1.8205 5.3202 1.6104 28.8509
SUP-HD1 CTRP2 1.8423 5.1725 1.6637 28.5993
HEL CTRP2 1.8442 3.486 1.8388 28.0006
THP-1 CTRP2 1.8482 4.4827 1.7778 28.1925
KMS-34 CTRP2 1.8872 3.9575 1.8646 27.7715
NU-DHL-1 CTRP2 1.9024 4.172 1.8656 27.7178
CMK CTRP2 1.9281 4.9472 1.7971 27.867
JeKo-1 CTRP2 1.96 3.9558 1.94 27.2778
NCI-H929 CTRP2 1.9831 4.0446 1.9587 27.1387
Ci-1 CTRP2 1.9885 4.3188 1.9432 27.1731
A4/Fukuda CTRP2 2.0086 2.8546 2.0086 26.887
BL-70 CTRP2 2.0138 3.2344 2.0131 26.8547
KMS-27 CTRP2 2.0246 5.5812 1.7748 27.6325
KCL-22 CTRP2 2.0394 8.8631 0.6768 31.1252
RPMI-6666 CTRP2 2.0406 3.0883 2.0403 26.6748
KMS-28BM CTRP2 2.1146 5.0575 1.9792 26.6411
HuT 78 CTRP2 2.1191 4.7952 2.0257 26.4669
SIG-M5 CTRP2 2.172 3.1122 2.1719 25.799
CA46 CTRP2 2.1906 3.8781 2.1805 25.7081
BV-173 CTRP2 2.2079 4.605 2.1449 25.772
OPM-2 CTRP2 2.2099 3.888 2.1999 25.5794
KMS-20 CTRP2 2.2187 3.8798 2.2092 25.5191
HuNS1 CTRP2 2.2501 3.5489 2.2482 25.2846
OCI-Ly19 CTRP2 2.2515 4.5585 2.1963 25.4549
CML-T1 CTRP2 2.2669 4.4279 2.2255 25.3054
KHM-1B CTRP2 2.3195 4.1435 2.3011 24.8775
PF-382 CTRP2 2.3515 4.6124 2.2961 24.7893
ALL-SIL CTRP2 2.3701 4.0599 2.3573 24.5213
Namalwa CTRP2 2.392 3.9376 2.3843 24.3585
GDM-1 CTRP2 2.4095 5.5372 2.2037 24.9232
DEL CTRP2 2.4196 2.9088 2.4196 24.1488
EJM CTRP2 2.4264 4.604 2.3762 24.2728
HT CTRP2 2.4339 4.3312 2.4079 24.1407
KMS-18 CTRP2 2.4679 4.7899 2.3986 24.0615
Karpas-422 CTRP2 2.4758 3.6561 2.4744 23.7794
MOLP-8 CTRP2 2.513 3.0879 2.513 23.5268
NCO2 CTRP2 2.5472 4.5326 2.5103 23.4232
MOLT-3 CTRP2 2.5496 4.1038 2.5396 23.3161
HEL 92.1.7 CTRP2 2.5784 4.3199 2.5586 23.1575
Granta-519 CTRP2 2.6485 6.9421 2.0595 24.699
AMO1 CTRP2 2.6742 3.1985 2.6742 22.4531
U-937 CTRP2 2.6757 4.1051 2.6684 22.4674
SU-DHL-10 CTRP2 2.6797 3.1771 2.6797 22.4164
MC116 CTRP2 2.6847 3.1217 2.6847 22.3829
NB4 CTRP2 2.6964 3.1128 2.6964 22.3046
SU-DHL-8 CTRP2 2.7094 4.551 2.6786 22.3217
SR CTRP2 2.7135 3.7443 2.7128 22.1933
SU-DHL-4 CTRP2 2.7146 4.3702 2.6967 22.2437
OCI-Ly10 CTRP2 2.7809 5.7475 2.5593 22.5087
L-363 CTRP2 2.81 4.6121 2.7789 21.6526
SU-DHL-1 CTRP2 2.8401 3.4563 2.8401 21.3476
TALL-1 [Human adult T-ALL] CTRP2 2.8776 6.4197 2.479 22.5004
KYO-1 CTRP2 2.9405 5.2426 2.8374 21.0304
MOLM-6 CTRP2 2.9449 5.6906 2.7515 21.3177
MM1.S CTRP2 2.9502 6.2963 2.5956 21.8595
KO52 CTRP2 2.9603 4.2733 2.9535 20.5696
SUP-T11 CTRP2 2.9842 4.7128 2.9527 20.4933
KMS-11 CTRP2 2.9892 4.3602 2.9799 20.3852
MOLP-2 CTRP2 2.9976 4.0501 2.9959 20.3038
HL-60 CTRP2 3.0949 5.0662 3.0303 19.869
SUP-B15 CTRP2 3.1217 5.2423 3.0325 19.7753
LAMA-84 CTRP2 3.2189 16.6835 -1.7809 33.5468
RL CTRP2 3.2468 4.938 3.2072 18.7717
MHH-CALL-4 CTRP2 3.2752 5.0374 3.226 18.6152
HD-MY-Z CTRP2 3.309 6.221 3.0092 19.2778
HPB-ALL CTRP2 3.5186 5.3536 3.4412 17.0908
LP-1 CTRP2 3.6942 5.4343 3.6167 15.9219
SK-MM-2 CTRP2 3.839 5.178 3.8072 14.7998
K-562 CTRP2 4.1344 6.3352 3.8739 13.6487
Mono-Mac-6 CTRP2 4.1859 13.1408 0.8491 24.6545
MHH-CALL-3 CTRP2 4.2145 8.6854 3.003 16.7977
KMM-1 CTRP2 4.2585 11.8916 1.5256 22.2388
P3HR-1 CTRP2 5.0566 9.4977 3.4385 13.009
Karpas-620 CTRP2 6.7863 8.3009 5.4581 1.3468
Toledo CTRP2 7.3799 10.9928 4.5751 4.0233
REC-1 CTRP2 8.089 12.8971 4.1352 4.8246
⏷ Show the Full List of 133 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 1.6954 4.7779 1.5743 29.3811
TE8 CTRP2 2.9185 6.2166 2.5845 21.9957
OE21 CTRP2 1.8629 3.1736 1.8618 27.8615
TE-11 CTRP2 2.398 3.6638 2.3959 24.2998
KYSE-30 CTRP2 2.5472 5.1945 2.4217 23.727
OE33 CTRP2 2.7495 4.9467 2.6779 22.1938
TE-6 CTRP2 2.9489 4.1151 2.9458 20.6329
TE-5 CTRP2 2.9754 5.8287 2.7514 21.2236
EC-GI-10 CTRP2 3.4919 5.6908 3.3468 17.506
TE-4 CTRP2 3.6434 6.2986 3.3505 17.0301
TE-14 CTRP2 3.7222 5.9494 3.5354 16.1218
KYSE-510 CTRP2 3.7289 4.6539 3.7255 15.4373
KYSE-410 CTRP2 4.2815 9.1674 2.8482 17.2372
COLO 680N CTRP2 4.4148 7.5775 3.6986 13.5353
KYSE-450 CTRP2 4.5498 6.3125 4.3329 10.7285
KYSE-520 CTRP2 4.5545 9.0815 3.1571 15.336
KYSE-150 CTRP2 4.681 9.9459 2.8668 16.1906
OE19 CTRP2 5.0102 7.8213 4.195 10.0309
KYSE-140 CTRP2 5.3657 7.541 4.6757 7.2125
TE-10 CTRP2 5.4335 11.4516 2.8162 14.7016
KYSE-70 CTRP2 5.7781 10.4469 3.6174 10.7136
KYSE-180 CTRP2 5.9885 8.9875 4.526 6.4908
TE-9 CTRP2 6.0367 8.9897 4.5653 6.2316
TE-1 CTRP2 6.25 11.5947 3.4387 10.5312
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 3.1384 6.5191 2.7317 20.8003
PaTu 8988s CTRP2 0.9697 8.6297 -0.365 37.3712
Panc 08.13 CTRP2 2.0993 5.1835 1.9398 26.8254
BxPC-3 CTRP2 2.3757 4.224 2.3545 24.5125
Panc 03.27 CTRP2 2.7175 3.2881 2.7175 22.1642
SW1990 CTRP2 2.75 6.0929 2.4357 23.0442
PSN1 CTRP2 3.0633 7.9595 2.1232 23.2528
MIA PaCa-2 CTRP2 3.2147 5.4314 3.0994 19.2469
YAPC CTRP2 3.2221 6.4424 2.8471 20.129
SU.86.86 CTRP2 3.2497 5.2354 3.1712 18.8858
Hs 766T CTRP2 3.338 5.9806 3.108 18.8331
Capan-2 CTRP2 3.4725 5.3072 3.3991 17.3844
HuP-T4 CTRP2 3.5564 5.9945 3.3427 17.3213
Capan-1 CTRP2 3.7988 6.1929 3.5516 15.8304
HuP-T3 CTRP2 3.961 8.3589 2.8915 17.8918
KP-4 CTRP2 4.0759 6.6878 3.6915 14.4976
Panc 02.03 CTRP2 4.5259 6.6041 4.2066 11.2695
PK-45H CTRP2 4.5449 11.7699 1.8528 20.3869
KP-2 CTRP2 4.5492 7.5962 3.8294 12.666
KP-3 CTRP2 4.5812 7.208 4.0282 11.801
L3.3 CTRP2 4.621 7.277 4.0407 11.6455
SNU-410 CTRP2 4.7131 7.9268 3.8495 12.1638
Panc 04.03 CTRP2 4.7586 7.2739 4.185 10.7139
DAN-G CTRP2 4.8396 6.2501 4.6681 8.6358
Panc 10.05 CTRP2 4.8437 8.46 3.7325 12.3114
QGP-1 CTRP2 4.8671 7.517 4.1897 10.4125
PaTu 8988t CTRP2 4.9212 7.647 4.186 10.2893
PK-59 CTRP2 4.9416 9.4744 3.3416 13.6691
CFPAC-1 CTRP2 5.0768 8.3805 3.9968 10.6756
PaTu 8902 CTRP2 5.4944 8.6901 4.2393 8.7199
HPAF-II CTRP2 6.2942 9.105 4.7169 5.1159
HPAC CTRP2 6.3331 12.5271 3.0403 11.9985
AsPC-1 CTRP2 6.7958 10.758 4.2807 6.0813
TCC-Pan2 CTRP2 7.0678 10.5804 4.5623 4.5093
SUIT-2 CTRP2 7.1872 9.0672 5.3456 1.3309
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 49 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 2.8256 10.6422 0.7164 28.6504
Malme-3M CTRP2 1.9136 6.7713 1.3188 29.5272
RPMI-7951 CTRP2 2.193 3.5257 2.1909 25.6654
LOX-IMVI CTRP2 2.6106 4.257 2.5955 22.9271
CJM [Human melanoma] CTRP2 2.6592 4.8116 2.5992 22.7555
WM88 CTRP2 2.7249 4.5829 2.6921 22.2253
WM266-4 CTRP2 2.7932 3.4462 2.7932 21.6599
Hs 294T CTRP2 2.8975 4.4505 2.8812 21.0198
WM115 CTRP2 2.9389 4.0935 2.936 20.6991
G-361 CTRP2 2.9687 7.0962 2.3514 22.6932
MeWo CTRP2 3.1978 5.1467 3.1289 19.1984
IGR-39 CTRP2 3.3078 7.1324 2.7033 20.4092
Hs 895.T CTRP2 3.3797 7.5132 2.6357 20.4567
HT-144 CTRP2 3.5251 4.855 3.5065 16.8465
IGR-37 CTRP2 3.6754 4.5081 3.6739 15.7876
UACC-257 CTRP2 3.7457 5.6745 3.6262 15.726
IPC-298 CTRP2 3.8337 6.715 3.4203 16.2123
A-375 CTRP2 3.8916 6.4978 3.5571 15.5346
Hs 944.T CTRP2 3.9736 6.398 3.6789 14.8431
K029AX CTRP2 4.1227 6.4459 3.8252 13.8631
WM983B CTRP2 4.1492 7.3734 3.5064 14.9985
A2058 CTRP2 4.1508 5.3036 4.1231 12.7089
A101D CTRP2 4.1756 5.3778 4.1408 12.5678
Hs 852.T CTRP2 4.258 10.053 2.4089 19.0023
RVH-421 CTRP2 4.3201 5.5631 4.2688 11.6621
SK-MEL-5 CTRP2 4.4363 5.2596 4.4261 10.7476
HMCB CTRP2 4.4549 6.2408 4.2523 11.3063
SK-MEL-1 CTRP2 4.4662 6.182 4.2826 11.1616
UACC-62 CTRP2 4.4958 6.0063 4.3646 10.7749
COLO 800 CTRP2 4.6155 6.8908 4.1934 11.0678
SK-MEL-24 CTRP2 4.6559 6.9355 4.2184 10.8603
SK-MEL-30 CTRP2 4.7478 6.733 4.396 9.9234
SK-MEL-3 CTRP2 4.7521 6.0577 4.6304 9.0358
SK-MEL-31 CTRP2 4.821 6.5461 4.5451 9.1497
COLO 829 CTRP2 4.8731 6.0621 4.7613 8.1951
Hs 839.T CTRP2 4.9353 9.6438 3.2536 14.0411
IGR-1 CTRP2 4.9645 6.5682 4.6906 8.192
WM793 CTRP2 5.2628 8.0248 4.3459 8.8064
SK-MEL-2 CTRP2 5.351 6.471 5.1399 5.3949
WM1799 CTRP2 5.4605 8.7927 4.1577 9.1335
COLO 792 CTRP2 5.6927 11.2163 3.1598 12.7721
Mel JuSo CTRP2 6.0255 8.887 4.6073 6.0768
Mel Ho CTRP2 6.0302 11.2717 3.4189 11.0339
SK-MEL-28 CTRP2 6.1476 8.2996 5.0016 4.1882
MDA-MB-435S CTRP2 6.2145 11.1483 3.6328 9.796
Hs 934.T CTRP2 6.3764 13.9257 2.3769 14.5254
Hs 936.T CTRP2 7.644 8.8008 5.667 0.1642
Hs 940.T CTRP2 8.0406 16.205 2.5164 11.1383
Hs 688(A).T CTRP2 10.4473 25.25 -0.1829 16.3513
⏷ Show the Full List of 49 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 3.3723 5.801 3.1909 18.4308
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-SH CTRP2 2.4668 3.8688 2.4622 23.8497
IMR-32 CTRP2 2.5161 3.2647 2.5161 23.506
SK-N-BE(2) CTRP2 2.6323 8.4938 1.4518 26.8671
CHP-212 CTRP2 2.7905 4.6613 2.754 21.8007
NH-6 CTRP2 3.266 6.1763 2.9753 19.5306
SK-N-DZ CTRP2 3.6498 5.6201 3.5336 16.3528
SK-N-FI CTRP2 3.9224 6.9371 3.4356 15.9008
SK-N-AS CTRP2 4.4195 6.1911 4.2289 11.4976
KP-N-YN CTRP2 5.0594 12.7061 1.8608 19.1751
NB1 CTRP2 6.0749 7.0946 5.5445 2.0431
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-28 CTRP2 1.1106 3.9327 1.0567 33.0477
SNU-478 CTRP2 2.2711 3.0913 2.2711 25.1382
SNU-1079 CTRP2 2.388 3.2857 2.3879 24.3599
SNU-869 CTRP2 4.3995 5.6561 4.3384 11.1677
SNU-1196 CTRP2 4.4172 7.8956 3.5628 14.0637
SNU-308 CTRP2 4.6993 7.4176 4.0617 11.3559
SNU-245 CTRP2 5.1777 8.5034 4.0346 10.2834
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U2OS CTRP2 1.496 4.925 1.3353 30.8384
SK-ES-1 CTRP2 1.9593 4.7182 1.8658 27.5315
TC71 CTRP2 1.9863 3.3093 1.9849 27.0405
G-292 clone A141B1 CTRP2 2.0213 5.9417 1.6815 27.963
SaOS-2 CTRP2 2.0799 5.8764 1.7626 27.4982
A-673 CTRP2 2.4285 4.6505 2.3734 24.2757
MHH-ES-1 CTRP2 2.718 6.8902 2.1525 24.1575
SW1353 CTRP2 3.0234 6.5212 2.6059 21.6022
SK-N-MC CTRP2 3.1827 5.1343 3.1146 19.2963
SJSA-1 CTRP2 3.314 6.2148 2.7446 14.5995
CAL-78 CTRP2 3.4101 4.6943 3.3973 17.5929
HOS CTRP2 3.7873 6.4814 3.4494 16.2396
Hs 822.T CTRP2 7.2861 8.0593 5.7954 0.0678
Hs 888.T CTRP2 8.0004 14.0696 3.5217 7.3304
MG-63 CTRP2 8.2752 20.9853 0.3418 18.0849
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 71 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-157 CTRP2 0.605 5.04 0.3492 37.0002
BT-549 CTRP2 1.5538 3.9197 1.521 30.0268
AU565 CTRP2 2.3539 4.4727 2.3128 24.7249
DU4475 CTRP2 2.4387 4.8303 2.3622 24.2809
MDA-MB-468 CTRP2 2.488 3.123 2.488 23.693
HCC1806 CTRP2 2.4908 3.9747 2.4838 23.6979
CAL-85-1 CTRP2 2.7408 5.6814 2.5314 22.7325
HCC202 CTRP2 2.916 5.6602 2.727 21.4946
MDA-MB-453 CTRP2 2.9345 4.585 2.9109 20.7977
SK-BR-3 CTRP2 3.1914 4.4954 3.1818 19.0392
HCC1569 CTRP2 3.2416 5.9083 3.0217 19.4381
HCC1395 CTRP2 3.288 6.6256 2.8596 19.8878
CAL-51 CTRP2 3.3287 5.5338 3.2028 18.525
HCC2218 CTRP2 3.4261 5.8911 3.2274 18.1345
HCC38 CTRP2 3.5485 7.9444 2.6404 19.9679
BT-20 CTRP2 3.9267 5.4628 3.8622 14.3282
HCC1954 CTRP2 4.0052 5.487 3.9427 13.7984
EFM-192A CTRP2 4.0477 5.9708 3.885 13.8694
BT-474 CTRP2 4.1458 5.7386 4.0472 12.9886
HDQ-P1 CTRP2 4.4028 7.4925 3.7224 13.4736
HCC1500 CTRP2 4.5001 7.2156 3.9401 12.363
JIMT-1 CTRP2 4.5267 8.2072 3.5345 13.8948
MDA-MB-231 CTRP2 4.7668 11.259 2.3084 18.169
ZR-75-30 CTRP2 4.818 6.2697 4.6383 8.8094
HCC1419 CTRP2 5.1311 6.9737 4.6996 7.7048
CAL-120 CTRP2 5.3664 7.2372 4.819 6.6285
T-47D CTRP2 5.3678 10.3447 3.3072 12.8545
HCC1143 CTRP2 5.3841 11.4081 2.7942 14.8951
HCC1428 CTRP2 5.457 9.2487 3.9298 10.0884
CAL-148 CTRP2 6.1262 10.8959 3.6864 9.7409
HCC1937 CTRP2 6.3026 9.2706 4.6411 5.4184
MCF-7 CTRP2 6.3526 9.2387 4.6963 5.099
MDA-MB-361 CTRP2 6.3891 9.3214 4.6836 5.0881
ZR-75-1 CTRP2 6.9308 10.9137 4.3031 5.7739
Hs 578Bst CTRP2 7.0476 12.917 3.4041 9.2616
KPL-1 CTRP2 7.1952 14.9693 2.501 12.5719
CAMA-1 CTRP2 7.7982 9.502 5.4675 0.5119
HMC-1-8 CTRP2 10.2785 25.1968 -0.274 16.8309
BT 416 CTRP2 2.1855 5.4955 1.9693 26.4485
BT164 CTRP2 3.0288 4.6947 3.0009 20.184
BT 145 CTRP2 3.272 5.6429 3.1182 19.0003
BT 139 CTRP2 3.3783 4.4801 3.3734 17.7785
BT 428 CTRP2 3.5855 4.7297 3.5763 16.4124
BT 239 CTRP2 3.6087 5.7324 3.4645 16.7253
BT 482 CTRP2 3.6939 5.2574 3.6434 15.8304
BT 112 CTRP2 3.7157 6.4235 3.3902 16.6694
BT 231 CTRP2 3.748 5.4067 3.6792 15.5333
BT 228 CTRP2 3.7963 5.1572 3.7643 15.0851
BT 159 CTRP2 3.8457 4.8099 3.8399 14.6676
BT 440 CTRP2 4.2262 8.931 2.9025 17.1633
BT 245 CTRP2 4.2657 6.374 4.0043 12.7798
BT 286 CTRP2 4.3804 6.4278 4.1109 12.0481
BT 504 CTRP2 4.6279 7.6084 3.905 12.1614
BT 422 CTRP2 4.6426 6.9427 4.2014 10.9621
BT 333 CTRP2 4.659 6.6897 4.3177 10.4708
BT 131 CTRP2 4.7064 7.2281 4.1504 10.9884
BT 330 CTRP2 4.7684 7.0136 4.3051 10.2174
BT 179 CTRP2 4.7879 6.5927 4.4923 9.4436
BT 187 CTRP2 5.0016 10.5776 2.8593 15.4782
BT 271 CTRP2 5.0535 7.47 4.3995 9.099
BT 248 CTRP2 5.1227 8.1007 4.1744 9.8408
BT 328 CTRP2 5.1465 12.0531 2.2624 17.4856
BT 224 CTRP2 5.1996 7.8895 4.3492 8.9433
BT 216 CTRP2 5.3496 8.3958 4.2492 9.0033
BT 172 CTRP2 5.3627 8.1902 4.3612 8.5108
BT147 CTRP2 5.4492 8.5631 4.2601 8.7336
BT 444 CTRP2 6.089 9.0489 4.5792 6.073
BT 232 CTRP2 6.2044 9.4719 4.4621 6.3482
BT 320 CTRP2 6.8794 12.6475 3.4103 9.5197
BT 340 CTRP2 7.0959 10.2048 4.7618 3.6674
BT 359 CTRP2 7.3008 10.114 4.937 2.7151
⏷ Show the Full List of 71 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 4.669 6.7264 4.3145 10.4551
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAS-1 CTRP2 1.1815 4.65 1.0428 32.8524
SF539 CTRP2 1.7225 4.4083 1.6532 29.0259
42-MG-BA CTRP2 1.9807 5.1889 1.8105 27.6511
D283 Med CTRP2 2.1992 3.9493 2.1865 25.6597
SF268 CTRP2 2.2711 4.8512 2.1802 25.4464
YH-13 CTRP2 2.3078 4.1117 2.2907 24.9509
Daoy CTRP2 2.4374 4.3601 2.4094 24.1243
T98G CTRP2 2.5627 5.4823 2.3822 23.8158
DK-MG CTRP2 2.6568 5.1296 2.551 22.9288
M059K CTRP2 2.7633 5.3222 2.6318 22.3091
SW1088 CTRP2 2.7728 6.2342 2.4204 23.0292
KNS-60 CTRP2 2.814 5.5864 2.4433 17.3386
SNU-738 CTRP2 2.8438 4.2804 2.8341 21.3555
A-172 CTRP2 3.0915 6.7591 2.6017 21.4152
8-MG-BA CTRP2 3.2142 5.7318 3.0351 19.4748
SNB-75 CTRP2 3.216 5.466 3.0942 19.2608
SNU-489 CTRP2 3.3201 5.1814 3.2547 18.3715
SF126 CTRP2 3.4275 7.7529 2.5912 20.4894
ONS-76 CTRP2 3.5309 6.5641 3.1436 18.1245
Hs 683 CTRP2 3.6296 6.013 3.4175 16.8287
SNU-201 CTRP2 3.8776 12.4317 0.9041 25.247
CCF-STTG1 CTRP2 3.8911 6.7887 3.4561 15.9132
GaMG CTRP2 3.908 5.8246 3.769 14.7147
Becker CTRP2 4.2704 7.4265 3.6119 14.2605
TM-31 CTRP2 4.3128 8.0911 3.3696 15.0984
GB-1 CTRP2 4.3494 9.141 2.9276 16.7544
SNU-626 CTRP2 4.521 7.7493 3.7335 13.1185
GOS-3 CTRP2 4.5235 7.8029 3.7124 13.1956
SF295 CTRP2 4.7147 7.6658 3.9683 11.6855
YKG-1 CTRP2 4.9912 8.6843 3.7693 11.808
U-118MG CTRP2 5.0276 8.0583 4.1015 10.3668
LN-18 CTRP2 5.0298 7.7282 4.2575 9.7296
KALS-1 CTRP2 5.0343 8.7337 3.787 11.6341
KNS-81 CTRP2 5.1938 7.0601 4.1582 3.6922
LN-229 CTRP2 5.4177 9.4994 3.7704 10.8358
KNS-42 CTRP2 5.9718 10.4631 3.7742 9.6743
SW1783 CTRP2 5.9808 11.6601 3.1834 12.096
DBTRG-05MG CTRP2 6.0195 8.3276 4.882 4.9344
U-251MG CTRP2 6.103 9.5433 4.3435 7.0364
SNU-1105 CTRP2 6.1614 10.1485 4.089 7.9934
KG-1-C CTRP2 6.1997 17.3098 0.5406 21.1983
SNU-466 CTRP2 6.5059 11.8933 3.4951 9.8279
GMS-10 CTRP2 6.8259 13.7387 2.8276 11.9482
U-87MG ATCC CTRP2 7.6897 9.2454 5.5198 0.4405
NMC-G1 CTRP2 7.8141 9.1282 5.6145 0.2015
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2 -1.1229 6.856 -2.0133 48.256
JHUEM-7 CTRP2 1.8812 3.0739 1.8807 27.7377
AN3-CA CTRP2 2.2278 3.9497 2.2159 25.4665
ESS-1 CTRP2 2.5096 4.0702 2.4999 23.5815
HEC-151 CTRP2 2.722 3.7081 2.7215 22.1358
JHUEM-1 CTRP2 2.7563 3.5995 2.7562 21.9059
RL95-2 CTRP2 2.8328 5.6537 2.6379 22.0689
KLE CTRP2 3.4842 7.3111 2.8252 19.4486
EN CTRP2 3.5418 5.6608 3.4076 17.135
MFE-296 CTRP2 3.7736 9.94 1.9864 21.8154
EFE-184 CTRP2 3.7935 4.9194 3.781 15.0375
JHUEM-3 CTRP2 4.2069 6.0438 4.0392 12.8283
MFE-319 CTRP2 4.4692 6.2808 4.2554 11.2524
HEC-1-A CTRP2 4.7771 9.2045 3.3146 14.1651
HEC-50B CTRP2 5.2279 8.2487 4.205 9.4661
HEC-59 CTRP2 6.0317 9.1795 4.4662 6.6579
HEC-1-B CTRP2 6.1513 11.7854 3.2625 11.4419
HEC-251 CTRP2 7.0625 9.9255 4.8726 3.2721
Ishikawa (Heraklio) 02 ER- CTRP2 7.5617 8.7725 5.6451 0.2268
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-54 CTRP2 1.9167 3.8613 1.9002 27.5544
KMRC-3 CTRP2 2.3121 4.5304 2.2632 25.0299
TUHR4TKB CTRP2 2.4308 3.1191 2.4308 24.0745
UO-31 CTRP2 2.4383 6.5505 1.96 25.691
OS-RC-2 CTRP2 2.5147 4.0723 2.505 23.5478
BFTC-909 CTRP2 2.6392 4.082 2.6319 22.7103
786-O CTRP2 2.6887 3.8852 2.6864 22.3638
KMRC-1 CTRP2 2.7619 4.0621 2.7573 21.8839
KMRC-2 CTRP2 2.7728 7.3994 2.0301 24.4337
TUHR10TKB CTRP2 2.8284 4.224 2.8204 21.452
Caki-2 CTRP2 2.9524 5.4962 2.8023 21.1151
A-498 CTRP2 3.0212 4.1439 3.0184 20.1504
ACHN CTRP2 3.594 5.8623 3.4177 16.9371
VMRC-RCW CTRP2 3.8706 6.2607 3.6097 15.403
769-P CTRP2 3.952 7.4118 3.2828 16.4014
VMRC-RCZ CTRP2 4.3844 8.3516 3.3256 15.0885
SNU-1272 CTRP2 4.7734 6.5673 4.4861 9.5084
RCC10RGB CTRP2 4.8117 7.3042 4.2268 10.4089
KMRC-20 CTRP2 5.5064 7.6653 4.7512 6.5715
TUHR14TKB CTRP2 6.9025 11.0792 4.2014 6.2367
Caki-1 CTRP2 8.9257 17.1217 2.6838 9.2322
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H716 CTRP2 1.3405 4.5602 1.2268 31.7155
SW48 CTRP2 1.6616 4.3602 1.5943 29.4247
GP2d CTRP2 1.6906 5.4414 1.443 29.8379
SNU-C1 CTRP2 1.8777 3.1455 1.8769 27.7618
COLO 320 CTRP2 2.1416 4.0427 2.1228 26.0642
HT115 CTRP2 2.1734 3.2408 2.173 25.7904
LoVo CTRP2 2.1876 4.5663 2.1279 25.896
SNU-81 CTRP2 2.2352 4.3534 2.1988 25.4996
SNU-C5 CTRP2 2.6008 5.09 2.4973 23.2941
MDST8 CTRP2 2.6397 3.1174 2.6397 22.6824
HCC-56 CTRP2 2.8916 3.4379 2.8916 21.0044
LS513 CTRP2 3.0768 5.4521 2.9462 20.2187
LS1034 CTRP2 3.1127 5.5219 2.971 20.0186
T84 CTRP2 3.1528 4.7961 3.1221 19.3676
SW620 CTRP2 3.1681 5.9947 2.9188 20.0323
SNU-1033 CTRP2 3.1906 4.9378 3.1478 19.157
CW-2 CTRP2 3.2465 8.2541 2.1954 22.4702
C2BBe1 CTRP2 3.2904 6.8388 2.7898 20.1384
COLO201 CTRP2 3.3384 4.7602 3.3189 18.0931
SNU-61 CTRP2 3.404 5.4453 3.3015 17.9414
SNU-407 CTRP2 3.4205 5.9835 3.1972 18.26
HCT 15 CTRP2 3.6288 5.3179 3.5651 16.3095
LS123 CTRP2 3.7562 4.9971 3.7369 15.3091
LS411N CTRP2 3.7633 5.7338 3.6324 15.649
SW948 CTRP2 3.8571 7.4108 3.1828 17.0469
NCI-H747 CTRP2 3.8701 5.6409 3.7683 14.8351
HT-55 CTRP2 3.9022 5.5594 3.8188 14.5571
KM12 CTRP2 3.9164 6.2062 3.676 15.0239
SNU-C2A CTRP2 3.9506 7.1732 3.3759 16.0484
COLO 678 CTRP2 4.0551 7.775 3.2408 16.2831
RKO CTRP2 4.085 5.7057 3.9881 13.3871
CL-11 CTRP2 4.0956 7.7446 3.2958 15.9607
HCT 8 CTRP2 4.1165 6.7532 3.7117 14.3053
SK-CO-1 CTRP2 4.2621 5.6394 4.193 12.1104
OUMS-23 CTRP2 4.2689 4.968 4.2665 11.8365
SNU-C4 CTRP2 4.4267 6.8208 4.0195 12.2597
DLD-1 CTRP2 4.638 7.0283 4.1619 11.1276
SW1417 CTRP2 4.719 7.5375 4.0295 11.4315
SNU-503 CTRP2 4.8437 7.3116 4.2566 10.2077
COLO205 CTRP2 4.9386 8.4276 3.8405 11.6434
RCM-1 [Human ESC] CTRP2 5.1796 9.3209 3.6394 11.9053
HCT 116 CTRP2 6.0806 10.8327 3.6803 9.8537
NCI-H508 CTRP2 6.1876 10.7333 3.8182 9.0759
HT-29 CTRP2 7.3246 8.5974 5.612 0.4016
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-423 CTRP2 2.592 5.4246 2.426 23.5702
HLF CTRP2 2.6822 4.7271 2.6333 22.5642
SNU-449 CTRP2 2.9312 5.7446 2.7238 21.4585
HuH-1 CTRP2 2.9578 5.8947 2.7156 21.4055
SNU-886 CTRP2 3.281 5.0069 3.2357 18.563
JHH-1 CTRP2 3.3588 4.6828 3.345 17.9382
SNU-387 CTRP2 3.3595 6.2351 3.06 18.9411
SNU-475 CTRP2 3.7064 6.7677 3.2643 17.1639
JHH-4 CTRP2 3.8697 5.5453 3.7863 14.7737
SNU-182 CTRP2 3.9461 6.2711 3.6888 14.8881
SNU-878 CTRP2 4.1864 5.7444 4.09 12.7104
SK-HEP-1 CTRP2 4.5444 5.4486 4.5234 10.0639
SNU-761 CTRP2 4.6641 8.5716 3.5037 13.6754
PLC/PRF/5 CTRP2 4.6669 6.5485 4.3786 10.2177
JHH-2 CTRP2 4.7654 10.0876 2.8781 15.9467
JHH-6 CTRP2 4.9391 5.4132 4.9365 7.3723
Hep-G2 CTRP2 4.9638 8.2316 3.9575 11.1067
JHH-5 CTRP2 5.1628 7.7953 4.3576 8.9979
Hep 3B2.1-7 CTRP2 6.451 11.1646 3.8147 8.6055
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 136 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H146 CTRP2 -0.478 5.9153 -1.0389 44.3903
HCC44 CTRP2 0.1591 2.3846 0.1531 39.228
NCI-H1838 CTRP2 0.9988 8.6478 -0.341 37.2157
NCI-H647 CTRP2 1.6769 5.0991 1.4989 29.6956
DV-90 CTRP2 1.7664 2.9636 1.766 28.5019
NCI-H209 CTRP2 1.8387 10.4091 -0.1858 34.0486
COR-L279 CTRP2 1.8817 5.8568 1.5513 28.8532
NCI-H2170 CTRP2 1.8917 4.96 1.7558 28.1256
RERF-LC-A1 CTRP2 1.8945 5.3996 1.6738 28.3961
COR-L88 CTRP2 1.937 24.4765 -6.7844 42.1332
SK-MES-1 CTRP2 1.994 4.9032 1.8752 27.3868
LXF 289 CTRP2 1.998 4.9772 1.8673 27.4006
NCI-H810 CTRP2 2.0123 5.0097 1.8772 27.3205
NCI-H1563 CTRP2 2.0973 5.4803 1.8766 27.0498
NCI-H1734 CTRP2 2.1026 4.1583 2.0753 26.3525
NCI-H1944 CTRP2 2.1842 3.5322 2.1819 25.7247
NCI-H2085 CTRP2 2.2319 12.1831 -0.5832 33.7669
NCI-H1755 CTRP2 2.2326 7.0535 1.5709 27.6758
NCI-H1703 CTRP2 2.2741 5.5721 2.0484 25.8929
NCI-H358 CTRP2 2.2828 4.4974 2.2356 25.2191
NCI-H211 CTRP2 2.2894 4.4572 2.2465 25.1609
COLO 668 CTRP2 2.296 5.6584 2.0523 25.81
NCI-H2009 CTRP2 2.3844 5.0625 2.269 24.7764
NCI-H1915 CTRP2 2.4153 4.0957 2.4021 24.2218
LOU-NH91 CTRP2 2.4229 5.7384 2.1713 24.9944
HCC15 CTRP2 2.4481 7.7046 1.5677 27.0255
NCI-H526 CTRP2 2.5582 5.7915 2.3058 24.0983
SHP-77 CTRP2 2.5698 4.3699 2.5465 23.2265
NCI-H1341 CTRP2 2.5699 3.155 2.5699 23.1475
HCC366 CTRP2 2.5919 4.3272 2.5722 23.0673
LK2 CTRP2 2.6381 5.0766 2.5395 23.0288
NCI-H838 CTRP2 2.681 4.4966 2.6533 22.5005
NCI-H1568 CTRP2 2.6905 3.5965 2.6903 22.345
NCI-H1694 CTRP2 2.693 6.1161 2.3671 23.4639
NCI-H1435 CTRP2 2.7367 5.0971 2.6421 22.3584
HCC2279 CTRP2 2.779 4.0523 2.7749 21.7684
DMS 114 CTRP2 2.7969 5.5226 2.6279 22.2169
Lu-99 CTRP2 2.8178 5.9668 2.544 22.449
HCC827 CTRP2 2.8302 4.9229 2.7671 21.6272
SK-LU-1 CTRP2 2.8757 6.1525 2.5562 22.2281
LUDLU-1 CTRP2 2.8775 6.3846 2.4897 22.4617
EPLC-272H CTRP2 2.8815 4.4243 2.8662 21.1229
NCI-H2087 CTRP2 2.9057 7.6654 2.0716 23.8946
NCI-H1693 CTRP2 2.9697 7.8402 2.0715 23.7092
HCC4006 CTRP2 3.0268 7.0686 2.424 22.2572
NCI-H1869 CTRP2 3.0732 5.6776 2.8941 20.4134
NCI-H520 CTRP2 3.1063 7.8079 2.2292 22.7426
NCI-H446 CTRP2 3.124 5.3568 3.0153 19.8278
EBC-1 CTRP2 3.1681 6.0915 2.8924 20.1272
NCI-H23 CTRP2 3.1696 5.2672 3.08 19.4576
NCI-H1623 CTRP2 3.1761 6.3914 2.813 20.3909
NCI-H1651 CTRP2 3.182 5.5138 3.0478 19.5308
NCI-H1666 CTRP2 3.1905 5.158 3.1194 19.2546
Sq-1 CTRP2 3.2259 5.4767 3.1028 19.1995
RERF-LC-MS CTRP2 3.2498 5.0848 3.193 18.8105
NCI-H2110 CTRP2 3.3138 5.3971 3.2129 18.5369
NCI-H1155 CTRP2 3.3295 5.8053 3.1433 18.7328
NCI-H522 CTRP2 3.3364 8.2178 2.3047 21.8152
ChaGo-K-1 CTRP2 3.3485 6.5045 2.9649 19.3217
NCI-H1105 CTRP2 3.3577 6.0452 3.1121 18.7577
NCI-H1373 CTRP2 3.3685 4.5376 3.3616 17.8501
NCI-H292 CTRP2 3.37 6.8634 2.8672 19.6194
LC-1/sq-SF CTRP2 3.3795 5.8976 3.1748 18.466
NCI-H2405 CTRP2 3.4407 10.1228 1.5705 24.1791
NCI-H661 CTRP2 3.4909 6.9739 2.9582 18.9307
SW1271 CTRP2 3.4985 11.1722 1.1397 25.4737
LCLC-97TM1 CTRP2 3.5453 4.9472 3.5204 16.7329
DMS 53 CTRP2 3.5486 5.4995 3.4478 16.9725
NCI-H1792 CTRP2 3.5567 8.5998 2.3706 20.9641
NCI-H1385 CTRP2 3.5636 8.0628 2.6069 20.0532
HARA [Human squamous cell lung carcinoma] CTRP2 3.5741 6.2009 3.3042 17.4069
Lu-65 CTRP2 3.5896 9.44 2.0312 22.1361
NCI-H1581 CTRP2 3.6102 5.6424 3.4859 16.6451
NCI-H322 CTRP2 3.6273 6.1667 3.3721 16.9999
NCI-H2029 CTRP2 3.8237 7.2901 3.1951 17.0924
NCI-H1339 CTRP2 3.8238 5.8199 3.6784 15.2973
NCI-H1793 CTRP2 3.8249 8.4448 2.7141 18.9378
RERF-LC-Ad2 CTRP2 3.8519 8.34 2.7877 18.5825
PC-14 CTRP2 4.0119 5.659 3.7057 8.5732
COLO 699 CTRP2 4.0251 6.7521 3.6138 14.9357
NCI-H2141 CTRP2 4.0744 7.0525 3.5545 15.0209
VMRC-LCD CTRP2 4.0895 7.1676 3.5257 15.0888
LCLC-103H CTRP2 4.1014 6.4102 3.8139 13.9676
COR-L105 CTRP2 4.1079 7.5532 3.3889 15.5659
HCC95 CTRP2 4.1082 10.2439 2.1729 20.2697
NCI-H1355 CTRP2 4.1102 9.3512 2.5932 18.6635
DMS 273 CTRP2 4.1201 6.2095 3.897 13.6067
HCC1588 CTRP2 4.1249 5.9074 3.9854 13.2725
HCC1833 CTRP2 4.1348 8.1025 3.1823 16.2999
NCI-H1650 CTRP2 4.1497 6.8571 3.7092 14.2204
Calu-3 CTRP2 4.1862 7.2431 3.5982 14.5432
T3M-10 CTRP2 4.2823 7.6068 3.5485 14.4755
NCI-H841 CTRP2 4.2983 6.5329 3.9861 12.752
NCI-H69 CTRP2 4.4046 6.8279 3.9932 12.4219
HCC1438 CTRP2 4.4176 6.2092 4.2214 11.5306
NCI-H2106 CTRP2 4.4354 6.442 4.1657 11.6837
NCI-H1184 CTRP2 4.5398 9.2599 3.0585 15.7659
NCI-H2081 CTRP2 4.5539 7.6634 3.8049 12.7506
NCI-H2228 CTRP2 4.6276 8.1318 3.6702 13.0975
NCI-H727 CTRP2 4.6987 6.6697 4.3678 10.1685
SBC-5 CTRP2 4.7771 15.3577 0.2936 24.9382
COR-L95 CTRP2 4.8167 7.174 4.288 10.155
A-549 CTRP2 4.8665 9.5401 3.2387 14.2614
CAL-12T CTRP2 4.9192 7.5429 4.231 10.1143
HCC2108 CTRP2 5.0129 9.7277 3.2856 13.7325
HCC1195 CTRP2 5.1613 9.2463 3.6588 11.8669
NCI-H2444 CTRP2 5.1781 7.8054 4.3678 8.9193
NCI-H1395 CTRP2 5.1785 6.9504 4.7585 7.3479
NCI-H650 CTRP2 5.2309 12.3269 2.2019 17.5298
NCI-H2342 CTRP2 5.2459 10.9942 2.8762 14.8669
Calu-6 CTRP2 5.3229 9.3461 3.7595 11.0889
NCI-H226 CTRP2 5.3233 8.4692 4.1888 9.3126
NCI-H2196 CTRP2 5.3511 7.752 4.5612 7.7156
HCC2935 CTRP2 5.365 8.812 4.0603 9.7498
HOP-92 CTRP2 5.5241 15.5694 0.8417 21.6402
NCI-H1299 CTRP2 5.5693 7.6618 4.8122 6.1754
HOP-62 CTRP2 5.5726 14.9073 1.2139 20.3245
NCI-H196 CTRP2 5.609 13.2969 2.0492 17.2937
EKVX CTRP2 5.6553 14.6992 1.3886 19.5592
SW1573 CTRP2 5.695 9.2737 4.1301 8.7458
NCI-H889 CTRP2 5.7849 7.7504 4.9665 5.0578
IA-LM CTRP2 5.923 9.3454 4.2916 7.6046
HCC78 CTRP2 5.9514 8.499 4.7388 5.6699
NCI-H2291 CTRP2 6.0409 9.6168 4.2552 7.5262
KNS-62 CTRP2 6.0823 9.335 4.4306 6.7104
Calu-1 CTRP2 6.119 14.9537 1.6518 17.6984
DMS 79 CTRP2 6.2299 9.7829 4.3274 6.866
NCI-H441 CTRP2 6.235 11.5414 3.4531 10.5
DMS 454 CTRP2 6.3323 9.7411 4.4302 6.2487
BEN CTRP2 6.5606 7.9494 5.4801 1.5412
NCI-H2126 CTRP2 7.103 9.7082 5.0017 2.7114
HCC1171 CTRP2 7.3033 11.6591 4.2044 5.612
NCI-H2172 CTRP2 7.3446 12.1862 3.978 6.465
NCI-H460 CTRP2 7.5832 14.9943 2.7781 10.8638
NCI-H2023 CTRP2 7.6028 12.1699 4.1628 5.3539
Hs 888.Lu CTRP2 4.8526 11.0489 2.4908 17.2693
⏷ Show the Full List of 136 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 0.7489 5.2603 0.459 36.1591
JHOM-1 CTRP2 1.2778 3.4304 1.2628 31.8058
SNU-840 CTRP2 2.2945 5.3182 2.1249 25.5621
EFO-27 CTRP2 2.3369 5.216 2.1906 25.199
OC 314 CTRP2 2.3677 2.9391 2.3677 24.4948
EFO-21 CTRP2 2.3945 4.0928 2.3809 24.3616
COV434 CTRP2 2.4114 4.4046 2.3789 24.3125
SNU-8 CTRP2 2.4181 2.8933 2.4181 24.1592
COV362 CTRP2 2.6441 7.1268 1.9904 24.9587
TYK-nu CTRP2 2.7772 5.3154 2.6481 22.2083
OVTOKO CTRP2 2.9201 4.5588 2.8978 20.8892
OAW42 CTRP2 2.9634 3.9487 2.9624 20.5293
COV644 CTRP2 2.9711 5.9553 2.7143 21.369
OV56 CTRP2 3.0049 4.5036 2.9892 20.3023
SNU-119 CTRP2 3.1107 5.4301 2.9871 19.9682
Caov-3 CTRP2 3.2024 6.8383 2.6947 20.747
IGROV-1 CTRP2 3.3522 5.3789 3.2576 18.2589
MCAS CTRP2 3.3988 5.503 3.285 18.0157
DOV13 CTRP2 3.6289 8.5201 2.4797 20.3577
OVK18 CTRP2 3.9127 4.864 3.9065 14.2225
TOV-21G CTRP2 3.9484 6.182 3.718 14.7748
FU-OV-1 CTRP2 4.0031 6.0571 3.8132 14.2642
OV7 CTRP2 4.0683 7.898 3.2022 16.3985
JHOS-2 CTRP2 4.112 6.8252 3.6806 14.4356
TOV-112D CTRP2 4.1632 6.4493 3.8681 13.5853
RMG-I CTRP2 4.2331 9.4947 2.6478 18.1423
ONCO-DG-1 CTRP2 4.4541 6.1656 4.2743 11.2284
OV-90 CTRP2 4.4691 5.9484 4.3504 10.9076
OVSAHO CTRP2 4.5098 10.7849 2.2991 18.8097
OVISE CTRP2 4.6946 5.2488 4.6923 9.0002
ES2 CTRP2 4.7152 7.1229 4.2038 10.7557
OVCAR-4 CTRP2 4.7723 8.8046 3.5003 13.4252
OVCAR-5 CTRP2 4.9869 10.9919 2.6422 16.3716
HEY A8 CTRP2 5.0373 8.6703 3.8202 11.4912
OVCAR-8 CTRP2 5.1564 8.6001 3.9677 10.608
OAW28 CTRP2 5.2 9.9647 3.3427 13.0775
Kuramochi CTRP2 5.2273 9.1611 3.7619 11.2928
SK-OV-3 CTRP2 5.8985 13.1927 2.348 15.5715
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 2.043 5.4502 1.8243 27.4037
P-STS CTRP2 3.5377 8.7481 2.2864 21.3309
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 2.4789 6.2666 2.0904 25.1057
Aska-SS CTRP2 2.9701 7.2523 2.2963 22.8908
GCT CTRP2 0.2191 5.0839 -0.0788 39.6038
A-204 CTRP2 0.3683 8.6215 -1.0048 40.8016
G-401 CTRP2 1.1003 4.9924 0.8953 33.6008
TTC-709 CTRP2 1.4465 6.2536 0.9679 32.1884
SW982 CTRP2 1.8327 4.5273 1.756 28.3173
Rh41 CTRP2 2.1335 4.3294 2.0944 26.1864
TE 617.T CTRP2 2.4369 3.8436 2.4323 24.0491
G-402 CTRP2 2.5628 5.5494 2.3677 23.8662
Tm87-16 CTRP2 2.5773 3.5393 2.577 23.0994
BT-16 CTRP2 2.6212 3.4719 2.6211 22.8063
TE 441.T CTRP2 2.6772 3.2118 2.6772 22.4325
BT-12 CTRP2 3.3931 3.8621 3.3931 17.6636
HT-1080 CTRP2 3.6679 6.216 3.4021 16.7685
Hs 729.T CTRP2 3.8692 7.3061 3.2372 16.8049
RD CTRP2 3.9874 6.1898 3.7581 14.5113
KYM-1 CTRP2 4.1886 9.5762 2.5658 18.5715
Rh18 CTRP2 4.3848 8.6476 3.1911 15.6217
SK-LMS-1 CTRP2 4.9995 11.2631 2.5201 16.821
RKN CTRP2 5.9727 8.8684 4.5722 6.3279
SK-UT-1 CTRP2 6.5018 12.3596 3.2595 10.799
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 2.641 5.1971 2.5225 23.0785
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2 2.514 7.4555 1.7315 26.2615
ACC-MESO-1 CTRP2 3.3288 7.4512 2.6055 20.7138
NCI-H2452 CTRP2 3.4198 6.0506 3.1784 18.33
MPP 89 CTRP2 3.7428 6.8037 3.2909 16.9595
IST-Mes1 CTRP2 4.4711 7.2112 3.9114 12.553
NCI-H2052 CTRP2 4.6744 9.0221 3.3021 14.4622
JL-1 CTRP2 6.039 11.4278 3.3482 11.3076
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC CTRP2 2.7955 5.4697 2.6376 22.1871
VCaP CTRP2 3.2024 5.202 3.1256 19.1953
22Rv1 CTRP2 4.6442 7.7428 3.8623 12.2889
PaCa-3 CTRP2 4.806 8.3746 3.7356 12.3909
DU145 CTRP2 5.4224 10.1094 3.4728 12.0562
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 2.2781 4.9359 2.1751 25.441
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GSS CTRP2 1.2301 2.5616 1.2297 32.0748
SNU-16 CTRP2 1.3154 2.8924 1.3134 31.5119
HGC-27 CTRP2 1.4747 4.6536 1.3567 30.8382
SNU-1 CTRP2 1.8334 5.352 1.6177 28.7844
NCC-StC-K140 CTRP2 1.9608 4.6563 1.8758 27.4925
LMSU CTRP2 2.4796 5.6386 2.2569 24.5164
23132/87 CTRP2 2.6253 4.0948 2.6173 22.8051
SNU-216 CTRP2 2.7486 6.6991 2.2496 23.7166
SH-10-TC CTRP2 2.9299 4.6569 2.9006 20.8477
SNU-620 CTRP2 2.9956 5.853 2.7674 21.104
IM95 CTRP2 3.0025 5.0337 2.9361 20.4909
ECC10 CTRP2 3.2687 5.5545 3.1335 18.957
MKN74 CTRP2 3.3287 6.5557 2.9268 19.5202
MKN1 CTRP2 3.6765 10.6258 1.5708 23.5524
SNU-5 CTRP2 4.1142 7.9113 3.2441 16.1127
MKN7 CTRP2 4.4216 9.0777 3.0283 16.1767
HuG1-N CTRP2 4.47 6.3667 4.2285 11.3492
Hs 746.T CTRP2 4.4729 7.2927 3.8796 12.672
ECC12 CTRP2 4.4826 6.3145 4.2592 11.1989
GSU CTRP2 4.5216 4.7843 4.5216 10.1449
SNU-668 CTRP2 4.6197 9.9781 2.7928 16.6294
NUGC-4 CTRP2 4.6569 6.3155 4.4483 9.9866
KATO III CTRP2 4.6762 12.4143 1.6579 20.7778
SNU-601 CTRP2 4.8861 7.698 4.1275 10.6125
NCI-N87 CTRP2 4.9921 7.9884 4.0994 10.4622
SNU-719 CTRP2 5.897 8.9569 4.4636 6.9347
AGS CTRP2 6.2814 8.8898 4.8141 4.7319
KE-39 CTRP2 6.5972 10.1068 4.4535 5.6922
NUGC-3 CTRP2 6.7823 11.1254 4.0896 6.8933
MKN45 CTRP2 7.2227 8.183 5.727 0.1901
SNG-M CTRP2 2.1834 3.7754 2.1764 25.7456
SNU-685 CTRP2 2.9383 6.1665 2.6205 21.8063
SNU-1077 CTRP2 5.1508 8.2221 4.1438 9.8988
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 1.5333 3.6828 1.514 30.1179
CGTH-W-1 CTRP2 1.9349 4.4811 1.8699 27.5968
8305C CTRP2 2.2564 3.9539 2.245 25.2744
TT CTRP2 2.4784 4.1651 2.4638 23.8059
FTC-238 CTRP2 2.7839 4.0431 2.78 21.7348
TT2609-C02 CTRP2 3.2765 7.8265 2.402 21.6211
B-CPAP CTRP2 3.4892 6.0345 3.2586 17.8293
BHT-101 CTRP2 3.6868 6.4349 3.3552 16.884
8505C CTRP2 3.9704 6.645 3.5926 15.173
ML-1 [Human leukemia] CTRP2 4.092 7.0053 3.5915 14.8303
FTC-133 CTRP2 5.9565 8.1552 4.9149 4.9203
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-10B CTRP2 1.6543 3.8932 1.6272 29.3381
SCC-4 CTRP2 1.7645 4.2697 1.7123 28.6886
BICR 18 CTRP2 2.0138 3.5149 2.0101 26.8647
BICR 6 CTRP2 2.2098 4.5035 2.1581 25.7211
HSC-3 CTRP2 2.3497 4.0558 2.3365 24.6588
BICR 22 CTRP2 2.3916 3.1758 2.3915 24.3358
BHY CTRP2 2.6198 4.7318 2.5668 22.9943
Detroit 562 CTRP2 2.6377 6.119 2.3059 23.8519
SNU-899 CTRP2 2.686 4.6107 2.6489 22.4988
HSC-4 CTRP2 2.7294 3.3066 2.7294 22.0849
PE/CA-PJ34 (clone C12) CTRP2 2.7778 4.618 2.7445 21.8745
CAL-27 CTRP2 2.8807 3.9899 2.8787 21.0837
BICR 31 CTRP2 2.935 5.4768 2.7875 21.2219
SNU-1076 CTRP2 3.0234 5.314 2.9143 20.4991
SCC-25 CTRP2 3.186 4.7525 3.1606 19.1282
BICR 16 CTRP2 3.2239 5.9757 2.9848 19.6244
YD-8 CTRP2 3.4404 7.4344 2.731 19.9273
CAL-33 CTRP2 3.4632 4.9815 3.4309 17.3052
HSC-2 CTRP2 3.5494 5.0902 3.5105 16.7535
SNU-46 CTRP2 3.5973 10.4168 1.5903 23.6929
PE/CA-PJ49 CTRP2 3.618 5.2348 3.5655 16.3433
FaDu CTRP2 3.8047 6.701 3.3938 16.3957
SCC-9 CTRP2 4.0313 7.3036 3.41 15.6937
PE/CA-PJ15 CTRP2 4.0496 6.526 3.7191 14.471
SNU-1041 CTRP2 4.0522 8.8059 2.7849 18.0683
BICR 56 CTRP2 4.2166 6.0803 4.0398 12.7967
SNU-1066 CTRP2 4.2343 9.2521 2.7621 17.6932
PE/CA-PJ41 (clone D2) CTRP2 4.6398 8.7397 3.4013 14.1471
SNU-1214 CTRP2 6.5181 13.3534 2.7768 12.7052
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1710 CTRP2 0.901 9.0129 -0.5875 38.0781
253J CTRP2 1.4841 3.2564 1.4785 30.4
5637 CTRP2 2.2276 4.8084 2.1398 25.7254
JMSU-1 CTRP2 2.245 4.3088 2.2126 25.4209
647V CTRP2 2.4858 3.1901 2.4858 23.708
T24 CTRP2 2.5646 4.9813 2.4753 23.4863
BC-3C CTRP2 2.5756 3.1246 2.5756 23.1099
UM-UC-3 CTRP2 2.9626 6.9424 2.3992 22.5368
U-BLC1 CTRP2 3.0918 6.1075 2.8047 20.6752
SCaBER CTRP2 3.6517 5.2231 3.603 16.1057
VM-CUB-1 CTRP2 3.908 6.3796 3.6134 15.2786
HT-1197 CTRP2 4.2341 6.2856 3.998 12.8965
KU-19-19 CTRP2 4.5791 5.9771 4.4632 10.1657
TCCSUP CTRP2 4.6261 12.5488 1.5459 21.2894
J82 CTRP2 4.64 8.2633 3.6225 13.2577
639V CTRP2 5.5077 8.8547 4.1702 8.978
HT-1376 CTRP2 5.5603 9.9552 3.6722 10.9374
KMBC-2 CTRP2 5.8063 9.8829 3.9233 9.382
RT-4 CTRP2 6.0096 14.3207 1.8772 17.1073
CAL-29 CTRP2 6.219 9.3171 4.5512 5.9473
253J-BV CTRP2 7.7567 9.4581 5.4664 0.5363
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 3.3694 5.8531 3.175 18.4965

References

1 FDA Approved Drug Products from FDA Official Website. 2023. Application Number: 216873
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
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4 Pharmacokinetics and disposition of momelotinib revealed a disproportionate human metabolite-resolution for clinical development. Drug Metab Dispos. 2018 Mar;46(3):237-247.
5 The effect of quercetin nanoparticle on cervical cancer progression by inducing apoptosis, autophagy and anti-proliferation via JAK2 suppression. Biomed Pharmacother. 2016 Aug;82:595-605. doi: 10.1016/j.biopha.2016.05.029. Epub 2016 Jun 9.