Details of the Drug

General Information of Drug (ID: DMFO7RP)

Drug Name
KW-2449
Synonyms Tumor antigen-specific mAb (cancer), Kyowa; Tumor antigen-specific monoclonal antibody (cancer), Kyowa Hakko Kirin; Tumor antigen-specific monoclonal antibody (cancer), Kyowa Hakko Kogyo
Indication
Disease Entry ICD 11 Status REF
Acute myeloid leukaemia 2A60 Phase 1 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 332.4
Logarithm of the Partition Coefficient (xlogp) 2.7
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C20H20N4O
IUPAC Name
[4-[(E)-2-(1H-indazol-3-yl)ethenyl]phenyl]-piperazin-1-ylmethanone
Canonical SMILES
C1CN(CCN1)C(=O)C2=CC=C(C=C2)/C=C/C3=NNC4=CC=CC=C43
InChI
InChI=1S/C20H20N4O/c25-20(24-13-11-21-12-14-24)16-8-5-15(6-9-16)7-10-19-17-3-1-2-4-18(17)22-23-19/h1-10,21H,11-14H2,(H,22,23)/b10-7+
InChIKey
YYLKKYCXAOBSRM-JXMROGBWSA-N
Cross-matching ID
PubChem CID
11427553
ChEBI ID
CHEBI:91441
CAS Number
841258-76-2
TTD ID
D00ABO
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fibroblast growth factor receptor 1 (FGFR1) TTRLW2X FGFR1_HUMAN Not Available [2]
Fms-like tyrosine kinase 3 (FLT-3) TTGJCWZ FLT3_HUMAN Not Available [2]
Tyrosine-protein kinase ABL1 (ABL) TT3PJMV ABL1_HUMAN Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Acute myeloid leukaemia
ICD Disease Classification 2A60
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Fibroblast growth factor receptor 1 (FGFR1) DTT FGFR1 4.79E-02 -0.03 -0.15
Fms-like tyrosine kinase 3 (FLT-3) DTT FLT3 2.11E-01 -0.05 -0.16
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 151 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 0.2138 2.1282 0.2116 38.8513
MEC1 CTRP2 2.04 4.8041 1.9398 27.0169
JM1 CTRP2 0.7576 4.9217 0.5379 35.9
EoL-1 CTRP2 -6.204 -3.6989 -6.2041 80.9554
MOLM-13 CTRP2 -3.233 -1.3452 -3.233 61.8002
MV4-11 CTRP2 -2.6984 0.2992 -2.7028 58.169
MOLT-3 CTRP2 -1.4663 -0.0005 -1.4663 50.0371
SUP-M2 CTRP2 -1.3231 0.6625 -1.3237 49.0841
Pfeiffer CTRP2 -1.1664 2.067 -1.1882 48.0636
SEM CTRP2 -1.1162 1.252 -1.119 47.7092
RS4;11 CTRP2 -0.9361 0.2818 -0.9361 46.5048
MOLP-8 CTRP2 -0.6004 5.5149 -1.0699 45.0024
ALL-SIL CTRP2 -0.49 0.884 -0.4901 43.5335
697 CTRP2 -0.4708 3.0399 -0.524 43.5316
KO52 CTRP2 -0.4609 3.5527 -0.5618 43.5647
OCI-Ly19 CTRP2 -0.4088 3.7009 -0.5239 43.2538
Mono-Mac-1 CTRP2 -0.2775 5.8477 -0.8022 43.1423
NALM-6 CTRP2 -0.2692 1.3746 -0.2695 42.0629
DEL CTRP2 -0.2433 0.2399 -0.2433 41.8894
Granta-519 CTRP2 -0.235 6.9058 -1.0618 43.3361
MOLM-6 CTRP2 -0.234 2.0105 -0.2384 41.841
EM-2 CTRP2 -0.1085 1.0987 -0.1085 40.9917
GA-10 CTRP2 -0.0646 2.7295 -0.0853 40.7603
KMS-26 CTRP2 -0.0612 0.9466 -0.0612 40.6762
Ku812 CTRP2 0.0583 1.8773 0.0571 39.8839
JURL-MK1 CTRP2 0.0632 1.052 0.0632 39.8478
A4/Fukuda CTRP2 0.3259 3.099 0.299 38.1819
OCI-AML-5 CTRP2 0.3471 1.0499 0.3471 37.9561
Peer CTRP2 0.3762 1.1668 0.3762 37.7622
OPM-2 CTRP2 0.4388 3.0386 0.4182 37.4116
KYO-1 CTRP2 0.5548 1.5419 0.5548 36.5722
CML-T1 CTRP2 0.5571 2.3042 0.5555 36.5627
SUP-B15 CTRP2 0.5725 4.4542 0.4197 36.9213
MOLT-16 CTRP2 0.5936 1.2583 0.5936 36.3138
P31/FUJ CTRP2 0.6022 3.3808 0.5685 36.3652
Ki-JK CTRP2 0.6368 1.626 0.6368 36.026
BV-173 CTRP2 0.6605 1.853 0.6604 35.8685
P12-Ichikawa CTRP2 0.6681 1.2458 0.6681 35.8179
Daudi CTRP2 0.6935 4.5554 0.5336 36.1454
SU-DHL-1 CTRP2 0.6941 1.1387 0.6941 35.6446
Kasumi-1 CTRP2 0.7184 2.9815 0.7068 35.5207
Mino CTRP2 0.8868 2.9058 0.8802 34.3825
HuT 78 CTRP2 1.029 5.1428 0.7881 34.1818
K-562 CTRP2 1.039 2.2974 1.0388 33.3475
KHM-1B CTRP2 1.0672 2.7874 1.0645 33.1681
LAMA-84 CTRP2 1.0712 2.3373 1.071 33.1327
TALL-1 [Human adult T-ALL] CTRP2 1.0988 3.6818 1.0643 33.0627
NCI-H929 CTRP2 1.1925 3.0003 1.188 32.3393
SIG-M5 CTRP2 1.2599 2.7183 1.2589 31.8782
OCI-AML-3 CTRP2 1.269 5.059 1.065 32.4835
OCI-AML-2 CTRP2 1.3152 2.1968 1.3152 31.5066
MOLM-16 CTRP2 1.3377 2.6318 1.3373 31.3583
KMS-34 CTRP2 1.4455 3.1056 1.4421 30.6499
HPB-ALL CTRP2 1.4554 3.5213 1.4412 30.6201
NU-DUL-1 CTRP2 1.4755 3.721 1.4524 30.5156
HL-60 CTRP2 1.5646 4.4511 1.4805 30.127
KMS-11 CTRP2 1.5889 3.723 1.5694 29.7483
RPMI-8402 CTRP2 1.6613 4.0497 1.6235 29.3274
Namalwa CTRP2 1.6654 4.5116 1.5801 29.4597
NOMO-1 CTRP2 1.6905 5.3428 1.4644 29.7668
Karpas-299 CTRP2 1.7362 3.3822 1.7314 28.7179
AML-193 CTRP2 1.7411 4.8472 1.6125 29.1024
CA46 CTRP2 1.7628 5.1033 1.591 29.1044
L-540 CTRP2 1.7907 4.2269 1.7438 28.4961
SU-DHL-10 CTRP2 1.799 2.2949 1.799 23.1644
MC116 CTRP2 1.8144 2.247 1.8144 28.1809
SET-2 CTRP2 1.83 3.5739 1.8222 28.1027
KMS-21-BM CTRP2 1.8334 4.1021 1.7991 28.1693
ST486 CTRP2 1.846 5.0908 1.6832 28.5211
PL21 CTRP2 1.8524 4.1699 1.8135 28.0584
PF-382 CTRP2 1.8597 4.3206 1.8075 28.0543
JJN-3 CTRP2 1.8694 4.1736 1.831 27.9431
NB4 CTRP2 1.9742 3.5153 1.97 27.1301
Ri-1 CTRP2 1.9996 4.0792 1.9736 27.0341
SKM-1 CTRP2 2.0038 3.9784 1.984 26.9853
Karpas-422 CTRP2 2.0322 3.8368 2.0199 26.7708
A3/Kawakami CTRP2 2.0717 3.3864 2.0701 26.4722
KM-H2 CTRP2 2.084 4.4979 2.0259 26.5805
TF-1 CTRP2 2.0898 4.315 2.0498 26.4807
RCH-ACV CTRP2 2.1268 5.0739 1.9895 26.5662
L-363 CTRP2 2.1756 3.9873 2.1606 25.8244
Mono-Mac-6 CTRP2 2.1958 8.9674 0.7983 30.2766
OCI-Ly10 CTRP2 2.2014 7.1247 1.5126 27.9707
SU-DHL-6 CTRP2 2.2687 3.5356 2.2671 25.1595
KMS-27 CTRP2 2.3058 4.5502 2.2546 25.0797
Hs 611.T CTRP2 2.313 5.2678 2.1549 25.3991
KMS-12-BM CTRP2 2.3401 4.5994 2.2855 24.8629
MM1.S CTRP2 2.3543 3.4195 2.3538 24.5858
MOLT-13 CTRP2 2.3648 4.6724 2.3034 24.7213
CMK CTRP2 2.3679 3.568 2.3666 24.4974
SUP-HD1 CTRP2 2.3729 4.9055 2.2812 24.7712
BL-70 CTRP2 2.3813 5.0178 2.2731 24.772
KMS-28BM CTRP2 2.3816 4.794 2.3062 24.6573
EB1 CTRP2 2.4013 6.1698 2.0337 25.5458
KCL-22 CTRP2 2.4186 4.3374 2.3916 24.2463
Ci-1 CTRP2 2.4218 5.4223 2.2418 24.7512
HH [Human lymphoma] CTRP2 2.4349 6.0312 2.1089 25.1767
SR CTRP2 2.4535 3.3652 2.4533 23.9236
OCI-M1 CTRP2 2.4554 4.2862 2.4333 23.9845
MOTN-1 CTRP2 2.4928 5.9977 2.181 24.7424
JeKo-1 CTRP2 2.5016 7.0725 1.8554 25.8657
KE-97 CTRP2 2.5937 5.432 2.4263 23.5634
KMS-20 CTRP2 2.6408 4.28 2.6254 22.7265
RPMI-6666 CTRP2 2.6544 4.7638 2.5998 22.7693
M-07e CTRP2 2.7099 5.6697 2.5004 22.9382
KE-37 CTRP2 2.7332 6.0698 2.4238 23.1381
MHH-CALL-4 CTRP2 2.7554 4.8191 2.7004 22.0978
KMS-18 CTRP2 2.7682 5.7189 2.5524 22.5727
Kasumi-2 CTRP2 2.7881 5.9293 2.5215 22.6208
DB CTRP2 2.8279 7.4043 2.0874 24.0654
F-36P CTRP2 2.8283 4.4509 2.8096 21.4885
SU-DHL-4 CTRP2 2.8446 4.7979 2.7062 16.2147
SUP-T1 CTRP2 2.8454 13.4762 -0.5862 32.0383
LP-1 CTRP2 2.8471 4.7299 2.8069 21.4363
AMO1 CTRP2 2.8814 4.1879 2.8509 15.5493
JVM-3 CTRP2 2.9393 6.0504 2.6541 21.6822
GDM-1 CTRP2 2.9709 6.5073 2.5532 21.9509
EJM CTRP2 2.9727 8.3567 1.8658 24.4395
DND-41 CTRP2 2.9881 5.1872 2.8978 20.669
U266B1 CTRP2 3.0204 5.0691 2.9503 20.3841
RPMI-8226 CTRP2 3.1282 5.1685 3.0511 19.6901
SU-DHL-8 CTRP2 3.1362 6.2001 2.5625 15.8749
Jurkat CTRP2 3.2046 5.4177 3.0912 19.3075
BDCM CTRP2 3.2122 7.1026 2.6115 21.0263
HEL 92.1.7 CTRP2 3.3068 5.7488 3.1321 18.8429
HEL CTRP2 3.3341 4.9115 3.3019 18.1648
HuNS1 CTRP2 3.3407 6.3204 3.0141 19.1646
OCI-Ly3 CTRP2 3.5235 6.7725 3.0649 18.4378
NU-DHL-1 CTRP2 3.6644 6.7045 3.2409 17.3731
MHH-CALL-3 CTRP2 3.6703 7.5783 2.9181 18.5755
U-937 CTRP2 3.7287 5.3977 3.6598 15.6621
Toledo CTRP2 3.7339 6.8481 3.2654 17.0807
WSU-DLCL2 CTRP2 3.9876 5.1603 3.9655 13.777
L-428 CTRP2 4.3139 6.358 4.0618 12.4254
KMM-1 CTRP2 4.3197 7.3549 3.6931 13.8114
RL CTRP2 4.3652 6.239 4.1552 11.9297
SK-MM-2 CTRP2 4.3762 6.4005 4.1154 12.0437
HD-MY-Z CTRP2 4.4141 6.0267 4.27 11.3646
THP-1 CTRP2 4.429 5.9292 4.3115 11.1701
HDLM-2 CTRP2 4.4834 6.7409 4.1103 11.7545
REC-1 CTRP2 4.5026 6.9718 4.0416 11.9637
EHEB CTRP2 4.5293 7.7649 3.7351 13.0906
SUP-T11 CTRP2 4.5527 7.7881 3.7488 12.9757
HT CTRP2 4.6997 5.7043 4.6538 9.1152
JVM-2 CTRP2 4.7431 6.0203 4.6307 9.0618
MOLP-2 CTRP2 4.7597 6.4894 4.4998 9.4957
P3HR-1 CTRP2 5.2187 7.4101 4.0034 4.3397
ME1 CTRP2 5.5292 6.2726 5.4067 3.8769
Karpas-620 CTRP2 6.4928 8.3898 5.2212 2.6848
Raji CTRP2 7.6232 8.9592 5.6007 0.2911
Reh CTRP2 7.7228 12.7555 3.9635 5.9779
⏷ Show the Full List of 151 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 2.1316 4.8137 2.0364 26.3901
TE15 CTRP2 3.6583 7.2019 3.0529 18.097
OE21 CTRP2 3.4403 7.4558 2.7225 19.9593
KYSE-70 CTRP2 4.2152 6.194 4.0054 12.9257
TE-10 CTRP2 4.3517 6.3869 4.0934 12.1972
TE-6 CTRP2 4.3534 5.6345 4.0752 6.0424
TE-11 CTRP2 4.4206 8.6783 3.2127 15.4459
TE-9 CTRP2 4.5576 6.8573 4.1451 11.4138
KYSE-180 CTRP2 4.5678 5.3498 4.5567 9.8746
TE-4 CTRP2 4.5759 5.7867 4.5041 10.0301
KYSE-150 CTRP2 4.7631 6.3097 4.5656 9.24
TE-14 CTRP2 4.889 6.0607 4.779 8.0829
KYSE-410 CTRP2 4.9349 6.2178 4.7821 7.9336
EC-GI-10 CTRP2 4.9895 9.4662 3.3907 13.3583
COLO 680N CTRP2 4.9943 7.0406 4.5293 8.7363
KYSE-140 CTRP2 5.0565 6.1998 4.9202 7.0653
TE-5 CTRP2 5.0844 12.0051 2.2305 17.7448
KYSE-30 CTRP2 5.1027 6.0398 5.018 6.5699
TE-1 CTRP2 5.112 6.7753 4.764 7.5032
OE33 CTRP2 5.3286 6.246 5.2002 5.2293
KYSE-510 CTRP2 5.4351 6.0785 5.3698 4.2887
KYSE-450 CTRP2 5.4642 6.089 5.3985 4.0966
OE19 CTRP2 5.4873 8.0007 4.5704 7.3619
KYSE-520 CTRP2 5.7316 8.0532 4.7688 5.9978
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 3.6777 6.7056 3.2549 17.2821
QGP-1 CTRP2 0.5921 7.5753 -0.3845 38.8046
MIA PaCa-2 CTRP2 1.8351 4.9556 1.6955 28.5146
KP-4 CTRP2 3.3855 6.517 3.0011 19.079
PaTu 8988s CTRP2 3.5423 7.5496 2.7941 19.4027
SNU-410 CTRP2 3.6493 12.4977 0.6549 26.5988
SW1990 CTRP2 3.8766 6.351 3.5883 15.4636
PSN1 CTRP2 3.8924 6.4873 3.5615 15.5161
HuP-T4 CTRP2 4.0067 6.14 3.7938 14.3232
TCC-Pan2 CTRP2 4.1146 6.9962 3.6191 14.6618
Hs 766T CTRP2 4.1708 5.3345 4.1408 12.5836
PK-59 CTRP2 4.2173 6.2039 4.0047 12.922
Panc 08.13 CTRP2 4.2257 5.619 4.1575 12.3496
KP-3 CTRP2 4.2525 7.1856 3.6914 14.0017
BxPC-3 CTRP2 4.2775 5.6372 4.2101 12.002
PK-45H CTRP2 4.3058 7.2007 3.7416 13.6615
HPAC CTRP2 4.4016 6.0291 4.2557 11.4547
AsPC-1 CTRP2 4.4315 8.842 3.1479 15.6764
PaTu 8988t CTRP2 4.4318 6.9977 3.9562 12.4878
HuP-T3 CTRP2 4.6 7.1406 4.0759 11.5646
SNU-213 CTRP2 4.6032 5.8149 4.5278 9.8609
DAN-G CTRP2 4.7126 5.6182 4.6813 8.979
SU.86.86 CTRP2 4.7733 6.0427 4.6577 8.8725
L3.3 CTRP2 4.8693 5.4258 4.8645 7.8447
Panc 05.04 CTRP2 4.8751 7.1947 4.3396 9.7979
YAPC CTRP2 4.9535 5.8941 4.8912 7.4828
PaTu 8902 CTRP2 4.9791 6.5125 4.7273 8.0112
Capan-2 CTRP2 5.036 5.8874 4.9825 6.9024
Panc 03.27 CTRP2 5.0496 9.9179 3.2268 13.8879
KP-2 CTRP2 5.0741 7.8107 4.2632 9.5974
SUIT-2 CTRP2 5.0871 7.3702 4.4787 8.6967
HPAF-II CTRP2 5.1026 6.4805 4.8716 7.1142
Capan-1 CTRP2 5.2587 7.4789 4.6 7.78
Panc 04.03 CTRP2 5.3515 7.5871 4.6401 7.3918
Panc 02.03 CTRP2 5.5808 6.3693 5.4236 3.6691
CFPAC-1 CTRP2 6.1232 8.3369 4.9631 4.395
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 3.0538 5.3366 2.9431 20.3024
IGR-39 CTRP2 2.5181 5.2914 2.3724 23.9909
Hs 895.T CTRP2 2.5328 5.2679 2.3927 23.8739
LOX-IMVI CTRP2 2.8876 4.658 2.8562 21.1369
CJM [Human melanoma] CTRP2 3.1204 6.0433 2.8536 20.4121
MeWo CTRP2 3.1949 6.0787 2.9252 19.9277
RPMI-7951 CTRP2 3.3764 4.4698 3.3717 17.7902
Hs 294T CTRP2 3.5156 7.3966 2.8257 19.3581
Hs 688(A).T CTRP2 3.687 5.6524 3.5671 16.118
WM88 CTRP2 3.7834 6.134 3.5519 15.8756
A-375 CTRP2 3.8935 6.1735 3.6606 15.1487
COLO 829 CTRP2 4.0749 5.9243 3.9265 13.6371
G-361 CTRP2 4.0814 5.7724 3.9698 13.4633
WM983B CTRP2 4.1306 8.6876 2.9174 17.3489
Hs 839.T CTRP2 4.2211 7.0512 3.7113 14.0118
Hs 940.T CTRP2 4.2655 5.5992 4.204 12.0614
WT2-iPS CTRP2 4.4071 6.7759 4.0155 12.3299
Mel Ho CTRP2 4.4517 5.8348 4.3587 10.9319
Mel JuSo CTRP2 4.4636 6.4157 4.2052 11.4544
Hs 852.T CTRP2 4.473 5.6344 4.4215 10.6448
SK-MEL-1 CTRP2 4.5519 6.2384 4.3588 10.6268
HMCB CTRP2 4.6218 8.1495 3.6563 13.1678
IGR-1 CTRP2 4.6401 7.4057 4.0057 11.7324
MDA-MB-435S CTRP2 4.81 6.6339 4.5004 9.3508
Hs 944.T CTRP2 4.8954 5.766 4.8541 7.796
IGR-37 CTRP2 4.9092 5.8921 4.8436 7.7893
WM1799 CTRP2 4.9767 6.0896 4.8665 7.5
Hs 934.T CTRP2 5.0257 6.159 4.8994 7.233
SK-MEL-5 CTRP2 5.0785 5.785 5.0481 6.5387
WM793 CTRP2 5.1084 6.1546 4.9908 6.6514
IPC-298 CTRP2 5.1456 5.9715 5.0824 6.2073
RVH-421 CTRP2 5.1508 9.3234 3.6114 12.0855
SK-MEL-24 CTRP2 5.1667 6.5172 4.9259 6.7274
WM266-4 CTRP2 5.1885 8.3601 4.1138 9.9328
K029AX CTRP2 5.2288 8.5885 4.0419 10.135
Hs 936.T CTRP2 5.2369 6.0189 5.1699 5.6133
UACC-62 CTRP2 5.3165 5.8572 5.2922 4.9321
HT-144 CTRP2 5.3407 9.255 3.8206 10.7966
SK-MEL-3 CTRP2 5.3604 10.9201 3.0154 14.058
COLO 800 CTRP2 5.365 6.1383 5.2754 4.8436
A101D CTRP2 5.3941 5.9268 5.3631 4.439
WM115 CTRP2 5.4034 5.9567 5.3667 4.3968
A2058 CTRP2 5.4185 5.9417 5.3863 4.2806
COLO 792 CTRP2 5.4537 6.3227 5.3069 4.4693
SK-MEL-30 CTRP2 5.4572 5.994 5.4166 4.0528
SK-MEL-28 CTRP2 5.8484 6.2231 5.7647 1.6183
SK-MEL-31 CTRP2 5.9158 7.6053 5.1543 3.9971
UACC-257 CTRP2 5.9659 9.896 4.0528 8.5212
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 3.5515 7.284 2.9074 18.9486
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IMR-32 CTRP2 -1.5237 0.1706 -1.5238 50.4196
CHP-212 CTRP2 0.111 4.6023 -0.1019 40.0972
SK-N-DZ CTRP2 0.3057 4.2581 0.1634 38.6462
CHP-126 CTRP2 0.9513 3.7854 0.9025 34.0913
NH-6 CTRP2 1.091 5.6496 0.7411 34.1065
Kelly CTRP2 1.7567 3.0715 1.7558 28.5683
NB1 CTRP2 1.8385 2.5327 1.8385 28.0201
SK-N-FI CTRP2 2.0297 4.2445 1.9928 26.8701
SK-N-SH CTRP2 2.0626 5.0456 1.9252 26.994
KP-N-SI9s CTRP2 2.4294 4.1683 2.4131 24.1382
SK-N-AS CTRP2 2.7723 7.3534 2.0466 24.3762
KP-N-YN CTRP2 3.0949 10.8376 0.8967 27.3427
SK-N-BE(2) CTRP2 3.8278 6.3969 3.5206 15.8574
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-478 CTRP2 4.2 5.6194 4.1296 12.5286
SNU-1196 CTRP2 4.3845 6.1709 4.1968 11.7198
HuH-28 CTRP2 4.4465 5.9369 4.3287 11.0549
HuCC-T1 CTRP2 4.7302 5.9398 4.6373 9.078
SNU-308 CTRP2 5.475 6.9482 5.0605 5.3842
SNU-245 CTRP2 5.5571 7.2409 5.0037 5.4159
SNU-869 CTRP2 5.8021 6.8478 5.4264 3.1063
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-ES-1 CTRP2 0.7298 2.3856 0.7285 35.411
CADO-ES1 CTRP2 0.9239 3.826 0.8703 34.289
A-673 CTRP2 1.0671 4.5396 0.9371 33.5829
SK-N-MC CTRP2 1.6732 2.3074 1.6732 29.1218
MHH-ES-1 CTRP2 1.998 4.2335 1.9605 27.0836
G-292 clone A141B1 CTRP2 2.2787 3.5181 2.2773 25.0924
TC71 CTRP2 2.401 4.7289 2.3351 24.4954
SJSA-1 CTRP2 2.7357 4.7751 2.6846 22.2158
MG-63 CTRP2 2.8943 6.2127 2.5592 22.1603
SaOS-2 CTRP2 2.9598 4.4963 2.943 20.6066
Hs 888.T CTRP2 3.0273 5.771 2.8222 20.8107
CAL-78 CTRP2 3.1285 4.5162 3.1161 19.4677
U2OS CTRP2 3.3303 4.8169 3.3063 18.1624
HOS CTRP2 3.7236 6.1115 3.493 16.2705
SW1353 CTRP2 4.1003 4.9329 4.0959 12.9666
Hs 822.T CTRP2 4.4065 5.7381 4.3303 11.1737
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DU4475 CTRP2 1.0427 2.4756 1.042 33.3243
MDA-MB-468 CTRP2 2.1014 4.4416 2.0501 26.4414
CAL-51 CTRP2 3.0822 5.6035 2.9205 20.2922
MDA-MB-157 CTRP2 3.3349 5.9925 3.1015 18.8656
HMC-1-8 CTRP2 3.4261 4.4088 3.4235 17.4523
BT-549 CTRP2 3.6726 6.3914 3.3535 16.9321
MDA-MB-231 CTRP2 3.946 6.562 3.5947 15.2357
MCF-7 CTRP2 3.9931 6.5369 3.6543 14.8767
MDA-MB-453 CTRP2 4.0871 5.9868 3.9238 13.6096
KPL-1 CTRP2 4.2659 7.1525 3.7188 13.859
CAL-120 CTRP2 4.2813 5.7276 4.1966 12.0373
HCC1395 CTRP2 4.5115 5.9236 4.4029 10.5894
HDQ-P1 CTRP2 4.6669 6.0755 4.5325 9.648
HCC1500 CTRP2 4.873 5.9477 4.7911 8.088
CAL-85-1 CTRP2 4.8928 6.7591 4.5397 8.9696
HCC1143 CTRP2 4.9508 6.4986 4.7021 8.1867
HCC1806 CTRP2 5.0842 5.9737 5.0149 6.6378
ZR-75-1 CTRP2 5.0888 6.8381 4.7135 7.7622
HCC38 CTRP2 5.1155 7.5033 4.4465 8.7544
Hs 578Bst CTRP2 5.2757 6.9171 4.8729 6.6417
UACC-812 CTRP2 5.3803 7.8631 4.5359 7.7507
HCC1954 CTRP2 5.4463 6.12 5.3696 4.2561
HCC2218 CTRP2 5.4939 6.6163 5.2287 4.6643
BT-20 CTRP2 5.5268 6.7817 5.1886 4.7394
HCC202 CTRP2 5.5518 7.4029 4.9209 5.768
BT-474 CTRP2 5.5556 6.3523 5.4039 3.8144
SK-BR-3 CTRP2 5.5619 6.508 5.3457 4.0239
T-47D CTRP2 5.6331 6.883 5.2473 4.2392
CAMA-1 CTRP2 5.6524 6.5349 5.4268 3.4674
HCC1937 CTRP2 5.7857 7.0719 5.3018 3.6596
ZR-75-30 CTRP2 5.8023 7.0131 5.346 3.439
HCC1428 CTRP2 5.8211 11.1664 3.295 11.9577
JIMT-1 CTRP2 5.9353 6.7726 5.5858 2.1492
MDA-MB-361 CTRP2 6.0486 7.2136 5.4633 2.4346
HCC1419 CTRP2 6.2509 7.5583 5.4519 2.1193
BT 440 CTRP2 2.1508 4.6042 2.0845 26.1637
BT 286 CTRP2 2.1523 9.7351 0.4293 31.4787
BT 416 CTRP2 2.2972 10.1767 0.3871 31.1528
BT 271 CTRP2 2.796 6.4704 2.3744 23.1242
BT 504 CTRP2 2.9942 5.6797 2.8076 20.9656
BT 330 CTRP2 3.5492 7.285 2.9047 18.9653
BT 482 CTRP2 3.5936 6.117 3.3496 17.1835
BT 239 CTRP2 3.6467 6.1372 3.4018 16.8336
BT 131 CTRP2 3.8373 6.4227 3.5227 15.8215
BT147 CTRP2 4.3056 7.395 3.6618 13.9715
BT 145 CTRP2 4.3913 10.4905 2.3285 18.9831
BT 228 CTRP2 4.5126 6.0352 4.3752 10.6851
BT164 CTRP2 4.5534 7.8492 3.7224 13.0788
BT 428 CTRP2 4.6115 8.4661 3.5006 13.8177
BT 172 CTRP2 4.6168 8.1749 3.6397 13.2468
BT 231 CTRP2 4.7487 6.5623 4.4615 9.6714
BT 139 CTRP2 4.8279 7.1882 4.2935 10.1038
BT 444 CTRP2 4.8368 6.5403 4.5643 9.0323
BT 245 CTRP2 4.8589 6.6848 4.533 9.0894
BT 340 CTRP2 4.9301 6.3314 4.7394 8.1062
BT 359 CTRP2 5.052 7.8693 4.2141 9.8506
BT 159 CTRP2 5.0574 6.2993 4.8882 7.1813
BT 333 CTRP2 5.1542 8.2107 4.1525 9.8554
BT 187 CTRP2 5.1842 6.6709 4.8829 6.845
BT 248 CTRP2 5.1906 6.4863 4.9634 6.5172
BT 216 CTRP2 5.4007 7.4984 4.7299 6.9077
BT 179 CTRP2 5.4448 6.9427 5.0328 5.5714
BT 422 CTRP2 5.4652 6.0914 5.3988 4.0926
BT 112 CTRP2 5.4786 5.9783 5.4436 3.8903
BT 328 CTRP2 5.5794 8.6634 4.3297 8.1579
BT 224 CTRP2 5.5895 7.4907 4.9143 5.708
BT 498 CTRP2 5.5977 6.6534 5.3182 4.0407
BT 232 CTRP2 5.6231 6.025 5.5898 2.9225
BT 320 CTRP2 5.9802 7.1081 5.4581 2.5912
⏷ Show the Full List of 69 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 4.8192 5.8328 4.7586 8.3707
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med CTRP2 2.1406 5.5683 1.904 26.8171
KNS-60 CTRP2 2.5196 3.7111 2.5179 23.4884
YH-13 CTRP2 2.526 3.7695 2.5238 23.4474
A-172 CTRP2 2.6553 7.6674 1.8035 25.5868
M059K CTRP2 2.7632 4.3714 2.7468 21.9149
SF539 CTRP2 2.7969 3.9436 2.7948 21.6423
Hs 683 CTRP2 2.8228 4.7034 2.784 21.5933
CAS-1 CTRP2 2.8334 4.4184 2.8168 21.4478
T98G CTRP2 2.8503 5.9505 2.5838 22.207
42-MG-BA CTRP2 2.8629 4.488 2.8431 21.2622
GaMG CTRP2 2.9146 4.1638 2.91 20.8663
SNU-738 CTRP2 3.1983 4.4794 3.1895 18.9908
SF126 CTRP2 3.3925 4.8505 3.3685 17.7479
YKG-1 CTRP2 3.5302 7.4929 2.8036 19.4007
SW1088 CTRP2 3.5591 5.275 3.4969 16.7687
LN-18 CTRP2 3.618 4.4757 3.6165 16.1699
GOS-3 CTRP2 3.8581 7.2276 3.2562 16.7636
SNU-489 CTRP2 3.863 4.7444 3.8595 14.5443
SF268 CTRP2 3.8926 5.2431 3.8566 14.4575
SNU-201 CTRP2 3.9599 4.9009 3.9533 13.9094
GMS-10 CTRP2 3.9663 6.6812 3.5754 15.249
SW1783 CTRP2 3.9777 6.8657 3.5214 15.4194
U-118MG CTRP2 4.0847 6.4014 3.7986 14.0732
SNU-1105 CTRP2 4.1426 4.8483 4.1409 12.6757
CCF-STTG1 CTRP2 4.1623 6.35 3.8995 13.4719
SNU-466 CTRP2 4.1785 4.8683 4.1769 12.4361
GB-1 CTRP2 4.1987 7.0532 3.6867 14.1684
ONS-76 CTRP2 4.3252 5.9713 4.1876 11.9327
SF295 CTRP2 4.3323 7.6599 3.5778 14.2279
KNS-81 CTRP2 4.4629 5.326 4.4491 10.5826
KG-1-C CTRP2 4.4749 5.6747 4.4164 10.6562
KALS-1 CTRP2 4.6695 5.9554 4.5673 9.5149
U-251MG CTRP2 4.7044 5.6781 4.6633 9.0675
SNU-626 CTRP2 4.7052 6.4454 4.4566 9.8145
8-MG-BA CTRP2 4.7351 7.6271 4.0063 11.4818
Daoy CTRP2 4.7466 6.5188 4.4751 9.626
DBTRG-05MG CTRP2 4.7558 5.7653 4.7033 8.7648
LN-229 CTRP2 4.7712 6.6007 4.4714 9.5702
DK-MG CTRP2 4.7866 6.4051 4.5587 9.1975
Becker CTRP2 4.8149 6.8733 4.4114 9.6788
TM-31 CTRP2 4.8348 6.6799 4.5092 9.2477
SNB-75 CTRP2 4.9742 6.0306 4.8802 7.4581
KNS-42 CTRP2 5.1275 8.3169 4.076 10.2316
U-87MG ATCC CTRP2 5.4843 6.2841 5.3542 4.2032
NMC-G1 CTRP2 5.6603 7.9587 4.7509 6.2268
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2 1.1011 3.547 1.0752 33.0188
JHUEM-7 CTRP2 2.3772 5.4713 2.1829 25.0982
AN3-CA CTRP2 3.1554 5.6953 2.9795 19.8548
ESS-1 CTRP2 4.2596 7.0216 3.7638 13.7039
MFE-296 CTRP2 4.6837 6.843 4.2846 10.5287
JHUEM-1 CTRP2 4.8683 10.0806 2.9784 15.3067
KLE CTRP2 4.8723 5.9001 4.8016 8.0533
HEC-151 CTRP2 4.9182 5.716 4.8869 7.6094
RL95-2 CTRP2 4.9772 6.2627 4.8136 7.6926
HEC-265 CTRP2 5.0556 5.8042 5.0202 6.7085
HEC-1-B CTRP2 5.0819 6.946 4.6606 7.9883
HEC-6 CTRP2 5.1924 6.1546 5.0823 6.066
EFE-184 CTRP2 5.2742 6.2759 5.131 5.6455
EN CTRP2 5.2833 5.998 5.226 5.2697
HEC-50B CTRP2 5.3589 6.8559 4.3854 2.3771
MFE-319 CTRP2 5.4299 6.8146 5.0757 5.4375
HEC-1-A CTRP2 5.4601 6.8424 5.0938 5.2882
HEC-108 CTRP2 5.4768 6.0229 5.4307 3.9421
JHUEM-3 CTRP2 5.5462 6.4127 5.3695 3.973
HEC-251 CTRP2 5.6927 6.9524 5.272 3.9957
HEC-59 CTRP2 5.7245 7.1487 5.2073 4.189
Ishikawa (Heraklio) 02 ER- CTRP2 6.1781 7.1707 5.5885 1.6732
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMRC-2 CTRP2 3.1647 5.2588 3.0761 19.487
TUHR4TKB CTRP2 3.598 5.3284 3.5304 16.5282
KMRC-3 CTRP2 3.9007 5.5343 3.8218 14.5513
CAL-54 CTRP2 3.9096 7.5622 3.177 16.9247
OS-RC-2 CTRP2 3.9847 5.9815 3.8134 14.3196
UO-31 CTRP2 4.0088 5.388 3.9616 13.7218
BFTC-909 CTRP2 4.0569 5.0921 4.0433 13.2866
TUHR10TKB CTRP2 4.569 5.2008 4.5656 9.8406
KMRC-1 CTRP2 4.7081 5.946 4.6117 9.2372
786-O CTRP2 4.7138 8.2259 3.7133 12.7087
TUHR14TKB CTRP2 4.8452 8.9854 3.4849 13.3127
VMRC-RCW CTRP2 4.8524 5.7018 4.8185 8.0567
RCC10RGB CTRP2 4.9839 5.9845 4.9029 7.3471
SNU-1272 CTRP2 5.0368 6.6483 4.7363 7.8154
VMRC-RCZ CTRP2 5.0668 7.6568 4.3273 9.3564
KMRC-20 CTRP2 5.1233 6.2742 4.9682 6.6911
769-P CTRP2 5.1532 5.8407 5.1188 6.0549
Caki-2 CTRP2 5.322 5.8825 5.2936 4.9099
A-498 CTRP2 5.456 6.1094 5.3833 4.1768
Caki-1 CTRP2 6.0579 12.1167 3.0195 12.6097
ACHN CTRP2 6.0744 9.2231 4.48 6.5178
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-175 CTRP2 0.0417 3.9009 -0.0698 40.2991
SW948 CTRP2 0.4734 9.0382 -5.5738 19.1712
SW48 CTRP2 1.3865 3.1703 1.3813 31.0488
KM12 CTRP2 1.3905 5.52 1.0985 31.9648
SNU-C1 CTRP2 2.5106 3.6038 2.5098 23.5454
GP2d CTRP2 2.9112 6.3259 2.5442 22.1632
LS513 CTRP2 3.0235 5.3459 2.9087 20.5185
SNU-81 CTRP2 3.1238 4.7723 3.0938 19.5584
HT115 CTRP2 3.2429 5.4301 3.1302 19.0503
COLO205 CTRP2 3.2439 5.3489 3.146 18.9917
CL-11 CTRP2 3.3438 7.8772 2.4526 21.2434
LS1034 CTRP2 3.4042 5.879 3.2066 18.2763
HCT 15 CTRP2 3.5789 6.2764 3.2869 17.4554
LoVo CTRP2 3.7641 5.7135 3.6378 15.6272
COLO201 CTRP2 3.7995 6.206 3.5485 15.8397
SK-CO-1 CTRP2 3.8672 5.8293 3.7234 15.003
LS411N CTRP2 4.134 5.1443 4.1198 12.775
SW620 CTRP2 4.1537 6.4301 3.8641 13.628
SW1417 CTRP2 4.1584 6.9318 3.6904 14.2672
SNU-C2A CTRP2 4.194 6.2293 3.9717 13.1125
C2BBe1 CTRP2 4.3363 7.8559 3.4972 14.5341
SNU-407 CTRP2 4.488 6.5044 4.2012 11.3987
MDST8 CTRP2 4.5228 5.2053 4.5182 10.1525
HCC-56 CTRP2 4.5273 6.5109 4.2414 11.1343
CCK-81 CTRP2 4.5398 6.1994 4.3576 10.6671
NCI-H747 CTRP2 4.599 5.689 4.5479 9.8039
SNU-1033 CTRP2 4.6142 5.6825 4.5654 9.6948
SNU-C5 CTRP2 4.6654 6.8128 4.2771 10.6079
LS180 CTRP2 4.6662 5.8906 4.5794 9.4823
SNU-61 CTRP2 4.7328 6.077 4.6039 9.19
HT-55 CTRP2 4.7855 6.8835 4.3762 9.8952
NCI-H508 CTRP2 4.8008 5.911 4.7212 8.5609
HT-29 CTRP2 4.8383 6.7664 4.479 9.354
COLO 678 CTRP2 4.849 10.1835 2.9102 15.6239
HCT 116 CTRP2 4.8783 6.0584 4.768 8.1549
CW-2 CTRP2 4.9555 6.3723 4.305 3.5181
DLD-1 CTRP2 5.0112 6.2576 4.8521 7.4501
LS123 CTRP2 5.022 5.8855 4.9677 6.9984
RKO CTRP2 5.0228 6.2201 4.877 7.3242
OUMS-23 CTRP2 5.0832 5.8507 5.0412 6.5478
RCM-1 [Human ESC] CTRP2 5.1275 7.5701 4.4277 8.8004
SNU-503 CTRP2 5.4202 6.5142 5.1953 4.9917
SNU-C4 CTRP2 5.5505 6.412 5.3743 3.9427
HCT 8 CTRP2 5.653 6.5473 5.4219 3.485
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-387 CTRP2 3.0615 5.9908 2.8036 20.772
Hep 3B2.1-7 CTRP2 3.2473 4.2603 3.2452 18.6417
Li-7 CTRP2 3.3892 5.6167 3.2513 18.1645
Hep-G2 CTRP2 3.7774 6.1865 3.5301 15.9731
HLF CTRP2 3.8091 5.9984 3.6173 15.5614
SNU-886 CTRP2 4.0222 5.7486 3.9107 13.8569
SNU-182 CTRP2 4.1607 5.8204 4.0452 12.9488
HuH-1 CTRP2 4.182 7.5571 3.4649 15.0704
SNU-449 CTRP2 4.2844 7.4027 3.6364 14.1276
JHH-5 CTRP2 4.3064 9.277 2.8217 17.279
SNU-398 CTRP2 4.3676 7.1687 3.3764 9.039
SNU-761 CTRP2 4.4863 6.0134 4.0417 5.8199
SNU-423 CTRP2 4.5465 6.4488 4.2837 10.9208
SNU-878 CTRP2 4.8891 7.5361 4.2035 10.301
SNU-475 CTRP2 5.0696 6.5794 4.7983 7.4866
JHH-4 CTRP2 5.0784 7.9282 4.2124 9.7929
SK-HEP-1 CTRP2 5.2072 6.1847 5.0889 5.9975
JHH-2 CTRP2 5.3021 6.5035 5.0751 5.7793
JHH-1 CTRP2 5.3281 6.3761 5.1524 5.4107
PLC/PRF/5 CTRP2 5.5244 6.0546 5.4741 3.6406
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 139 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LC-1F CTRP2 0.2454 34.2719 -18.2609 40.9382
VMRC-LCD CTRP2 0.7355 3.4329 0.7034 35.473
NCI-H2081 CTRP2 0.9737 6.8132 0.283 35.816
DV-90 CTRP2 1.0488 5.6214 0.7019 34.3728
COR-L51 CTRP2 1.1276 4.9403 0.9347 33.3823
NCI-H1703 CTRP2 1.1772 5.3594 0.9028 33.3114
NCI-H2106 CTRP2 1.5744 5.1771 1.3727 30.4547
Lu-99 CTRP2 1.609 3.9205 1.5784 29.6515
NCI-H1341 CTRP2 1.6815 4.1869 1.6329 29.2293
HCC44 CTRP2 1.6929 3.6392 1.6799 29.0337
NCI-H2228 CTRP2 1.9561 4.5578 1.8834 27.4819
NCI-H810 CTRP2 2.0214 7.7928 1.0775 29.9621
LUDLU-1 CTRP2 2.1543 6.1035 1.7827 27.1936
HCC15 CTRP2 2.2235 6.6557 1.6929 27.2865
NCI-H1581 CTRP2 2.3001 5.8312 2.0144 25.9293
LOU-NH91 CTRP2 2.3463 4.0043 2.3352 24.6742
NCI-H841 CTRP2 2.39 6.3758 1.961 25.8362
HARA [Human squamous cell lung carcinoma] CTRP2 2.4953 5.6017 2.2824 24.3775
COLO 668 CTRP2 2.594 5.7487 2.3553 23.812
NCI-H522 CTRP2 2.6274 7.5898 1.8031 25.671
NCI-H446 CTRP2 2.6714 5.4084 2.5154 23.0067
NCI-H2141 CTRP2 2.7055 6.0234 2.4062 23.2862
PC-14 CTRP2 2.714 5.3546 2.5723 22.6731
NCI-H23 CTRP2 2.7589 6.1686 2.4242 23.0581
Lu-65 CTRP2 2.7908 6.0255 2.4988 22.6932
NCI-H1975 CTRP2 2.8222 4.2564 2.8129 21.4976
HCC95 CTRP2 2.9545 6.1429 2.645 21.6686
HCC827 CTRP2 2.963 5.4424 2.8248 21.0031
NCI-H1155 CTRP2 3.0384 6.077 2.7549 21.0173
NCI-H211 CTRP2 3.0713 5.4094 2.9485 20.2278
NCI-H1105 CTRP2 3.0745 6.8909 2.5381 21.6986
NCI-H2405 CTRP2 3.0894 6.974 2.5251 21.703
NCI-H526 CTRP2 3.1147 5.5414 2.9691 20.0189
NCI-H69 CTRP2 3.1461 7.9578 2.2113 22.6948
HCC1588 CTRP2 3.1764 5.202 3.0977 19.3746
NCI-H2009 CTRP2 3.196 5.9833 2.9523 19.8265
SK-MES-1 CTRP2 3.2011 5.2512 3.1164 19.2309
NCI-H1694 CTRP2 3.2463 5.557 3.1086 19.115
NCI-H838 CTRP2 3.2822 6.3902 2.9289 19.6507
HCC1195 CTRP2 3.2858 5.3932 3.1834 18.7283
NCI-H1563 CTRP2 3.3044 4.7153 3.2866 18.3141
A-549 CTRP2 3.3305 5.2468 3.2561 18.3333
HCC2108 CTRP2 3.4659 5.3937 3.3777 17.4794
CAL-12T CTRP2 3.515 4.8547 3.4961 16.9147
NCI-H889 CTRP2 3.5468 6.9969 3.01 18.576
DMS 114 CTRP2 3.5498 5.4385 3.4602 16.9254
LXF 289 CTRP2 3.5541 5.1397 3.5097 16.7408
SW1271 CTRP2 3.556 7.0177 3.0123 18.5409
NCI-H358 CTRP2 3.5913 7.5118 2.861 19.0124
NCI-H146 CTRP2 3.5977 6.9426 3.0845 18.1503
NCI-H1184 CTRP2 3.6194 5.5542 3.5138 16.5181
NCI-H1734 CTRP2 3.6755 5.7402 3.5354 16.2661
NCI-H2029 CTRP2 3.6787 8.5602 2.5135 20.0951
LK2 CTRP2 3.68 5.9523 3.4886 16.4187
NCI-H1623 CTRP2 3.7384 7.3269 3.09 17.7312
EBC-1 CTRP2 3.8501 6.1542 3.6188 15.4315
NCI-H1092 CTRP2 3.8779 7.853 3.0232 17.6039
NCI-H647 CTRP2 3.9583 6.6405 3.5811 15.2508
NCI-H520 CTRP2 3.9954 7.0102 3.4863 15.5024
NCI-H2126 CTRP2 4.0014 6.4478 3.6929 14.7093
HOP-62 CTRP2 4.0115 5.9119 3.8606 14.068
ChaGo-K-1 CTRP2 4.0359 7.3638 3.3907 15.7553
NCI-H292 CTRP2 4.0509 6.1809 3.8301 14.0584
HCC2279 CTRP2 4.0637 5.5665 3.9921 13.4405
NCI-H1755 CTRP2 4.0951 5.7541 3.9887 13.3535
NCI-H727 CTRP2 4.1128 6.0219 3.9424 13.4639
COR-L95 CTRP2 4.1353 6.5289 3.8111 13.8787
LCLC-103H CTRP2 4.171 4.9409 4.1676 12.4921
NCI-H1568 CTRP2 4.1932 7.1526 3.6417 14.3564
SK-LU-1 CTRP2 4.2409 5.6584 4.1665 12.2701
NCI-H650 CTRP2 4.2644 6.9497 3.7968 13.5643
COLO 699 CTRP2 4.2658 6.5976 3.9284 13.0619
HCC1438 CTRP2 4.2768 6.404 4.0064 12.7392
RERF-LC-A1 CTRP2 4.3083 5.5406 4.2598 11.7311
NCI-H2122 CTRP2 4.4147 5.8415 4.3169 11.1952
RERF-LC-MS CTRP2 4.4237 6.411 4.1635 11.726
NCI-H2110 CTRP2 4.4314 8.2006 3.4413 14.5091
NCI-H1573 CTRP2 4.4462 5.6378 4.392 10.8323
NCI-H1915 CTRP2 4.4772 6.3911 4.2282 11.3292
HOP-92 CTRP2 4.4842 6.3243 4.2578 11.1992
NCI-H1944 CTRP2 4.4936 15.58 -0.0703 26.6048
NCI-H1435 CTRP2 4.5251 5.2654 4.5178 10.1463
MOR/CPR CTRP2 4.5347 5.1325 4.5326 10.0646
NCI-H2085 CTRP2 4.5436 5.8054 4.1946 5.0064
SHP-77 CTRP2 4.5635 5.9003 4.4652 10.2067
EKVX CTRP2 4.5819 6.1199 4.4271 10.2875
EPLC-272H CTRP2 4.6033 6.0206 4.4781 10.0378
NCI-H1650 CTRP2 4.6099 7.0398 4.1277 11.3367
HCC366 CTRP2 4.6223 5.9007 4.5292 9.7967
NCI-H1355 CTRP2 4.6297 7.9713 3.7452 12.7924
NCI-H1666 CTRP2 4.6334 5.6938 4.5841 9.5688
NCI-H1385 CTRP2 4.7135 6.243 4.5332 9.5061
NCI-H1373 CTRP2 4.7451 6.4954 4.482 9.6045
NCI-H1693 CTRP2 4.7536 6.7396 4.3995 9.8935
RERF-LC-Ad2 CTRP2 4.7688 7.724 3.9973 11.4313
HCC1833 CTRP2 4.7917 7.3032 4.2066 10.5414
NCI-H2170 CTRP2 4.8009 8.9176 3.4744 13.461
NCI-H1838 CTRP2 4.8033 6.4431 4.5634 9.1312
COR-L105 CTRP2 4.8129 8.3524 3.7528 12.3044
DMS 53 CTRP2 4.8485 6.4541 4.6083 8.833
COR-L88 CTRP2 4.8727 7.3191 4.2831 10.027
NCI-H2030 CTRP2 4.9209 5.846 4.8662 7.6727
NCI-H661 CTRP2 4.9261 6.4349 4.2482 3.8379
NCI-H460 CTRP2 4.9419 6.0949 4.8271 7.7484
NCI-H1299 CTRP2 4.9697 6.9153 4.5567 8.6946
NCI-H196 CTRP2 4.9831 6.6704 4.6706 8.2167
NCI-H2087 CTRP2 4.9911 6.4924 4.7477 7.8999
Sq-1 CTRP2 5.0147 5.8474 4.9677 7.0214
NCI-H1792 CTRP2 5.0191 7.7068 4.2567 9.7596
NCI-H1869 CTRP2 5.0292 6.5537 4.7652 7.7259
DMS 454 CTRP2 5.0643 6.9084 4.6583 8.0441
NCI-H441 CTRP2 5.066 6.8938 4.6663 8.0083
NCI-H2023 CTRP2 5.0722 7.2888 4.5002 8.6486
RERF-LC-Ad1 CTRP2 5.0985 6.1047 4.995 6.6657
Calu-1 CTRP2 5.113 6.8503 4.7336 7.6192
NCI-H2444 CTRP2 5.1649 6.5218 4.4035 2.6465
Calu-6 CTRP2 5.2302 6.1105 5.137 5.7526
HCC4006 CTRP2 5.2331 7.6872 4.4773 8.3403
HCC78 CTRP2 5.2562 6.2551 5.1186 5.7438
T3M-10 CTRP2 5.2762 6.7209 4.9583 6.3033
NCI-H1395 CTRP2 5.3236 10.6704 3.1062 13.77
NCI-H2342 CTRP2 5.3302 7.6638 4.583 7.6759
Calu-3 CTRP2 5.3364 6.2707 5.1999 5.2078
NCI-H226 CTRP2 5.3393 9.9185 3.4923 12.156
NCI-H1339 CTRP2 5.386 9.9681 3.5101 11.9813
DMS 273 CTRP2 5.4777 6.1144 5.4055 4.0307
LC-1/sq-SF CTRP2 5.4814 6.0243 5.4353 3.9113
NCI-H1793 CTRP2 5.5506 7.7669 4.7436 6.5019
HCC2935 CTRP2 5.5508 6.7298 5.2363 4.4873
NCI-H2196 CTRP2 5.5843 6.1472 5.5109 3.3271
NCI-H2172 CTRP2 5.6487 6.9805 5.2162 4.3289
BEN CTRP2 5.7242 6.3796 5.5688 2.7177
NCI-H2291 CTRP2 5.7419 7.1216 5.2368 4.0274
KNS-62 CTRP2 6.002 7.3953 5.3333 3.0719
SBC-5 CTRP2 6.0451 6.893 5.6207 1.7793
HCC1171 CTRP2 6.7175 9.5686 4.8069 4.0375
NCI-H2286 CTRP2 7.6549 9.3 5.4831 0.5491
NCI-H322 CTRP2 7.9064 15.2256 2.8978 9.8963
Hs 888.Lu CTRP2 3.0337 6.5028 2.623 21.5094
⏷ Show the Full List of 139 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 1.0911 3.9887 1.0308 33.1983
A2780 CTRP2 2.3026 4.836 2.2161 25.2213
Caov-3 CTRP2 3.1568 5.9893 2.908 20.1055
COV434 CTRP2 3.3078 6.2005 3.0139 19.2643
JHOS-2 CTRP2 3.68 6.6572 3.2741 17.204
COV362 CTRP2 3.8153 7.7021 3.0205 17.7846
OV7 CTRP2 3.9018 6.482 3.5735 15.4437
JHOM-1 CTRP2 4.0626 5.7587 3.9524 13.5834
SNU-119 CTRP2 4.3937 6.0809 4.2329 11.5607
FU-OV-1 CTRP2 4.4189 6.1747 4.2332 11.484
OVCAR-5 CTRP2 4.4325 6.6145 4.1022 11.9298
COV644 CTRP2 4.4334 6.2865 4.2146 11.5086
OC 314 CTRP2 4.661 5.2122 4.659 9.2228
IGROV-1 CTRP2 4.7157 6.4382 4.4705 9.7326
DOV13 CTRP2 4.7458 7.1182 4.2378 10.5409
SK-OV-3 CTRP2 4.8199 5.993 4.7217 8.4998
SNU-840 CTRP2 4.8702 6.0647 4.7574 8.2179
OVCAR-8 CTRP2 4.8756 5.7272 4.8394 7.9101
OV-90 CTRP2 4.9538 6.5357 4.6914 8.2191
TYK-nu CTRP2 5.0332 6.7407 4.6955 7.9829
OVTOKO CTRP2 5.0431 6.1405 4.9239 7.0914
TOV-112D CTRP2 5.0661 9.5877 3.4035 13.1302
RMG-I CTRP2 5.1202 7.0669 4.6476 7.9389
MCAS CTRP2 5.1247 6.6549 4.8267 7.2252
OAW42 CTRP2 5.1446 8.3798 4.0624 10.2469
SNU-8 CTRP2 5.1574 6.0631 5.0713 6.211
OAW28 CTRP2 5.1582 7.1311 4.6581 7.7988
OVCAR-4 CTRP2 5.2852 6.735 4.9616 6.2665
EFO-21 CTRP2 5.2965 8.7257 4.0389 9.9927
EFO-27 CTRP2 5.3007 8.2957 4.2516 9.1055
JHOC-5 CTRP2 5.3381 5.9018 5.3073 4.811
OVK18 CTRP2 5.386 6.012 5.3344 4.5658
HEY A8 CTRP2 5.3965 7.2655 4.8355 6.488
TOV-21G CTRP2 5.4026 6.9251 4.9984 5.8156
ONCO-DG-1 CTRP2 5.4056 6.7259 5.09 5.4434
ES2 CTRP2 5.4818 6.4933 5.2686 4.5397
Kuramochi CTRP2 5.4889 6.8625 5.1137 5.1352
OV56 CTRP2 5.5024 5.9836 5.4684 3.7284
OVISE CTRP2 5.5874 6.0343 5.5484 3.1807
OVSAHO CTRP2 5.6676 6.637 5.3959 3.5525
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SYO-1 CTRP2 1.7824 5.7194 1.4777 29.4226
H-STS CTRP2 2.2902 5.4427 2.0945 25.6814
P-STS CTRP2 5.2865 13.6712 1.5823 19.6718
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 3.903 6.4066 3.5994 15.3445
Yamato-SS CTRP2 4.276 5.7557 4.185 12.0947
TE 441.T CTRP2 1.1271 5.1472 0.8936 33.5135
A-204 CTRP2 1.5321 4.391 1.4533 30.3253
TTC-709 CTRP2 1.8149 5.5455 1.5547 29.0576
G-402 CTRP2 1.9743 5.65 1.7037 28.0375
SW982 CTRP2 2.1608 4.2341 2.1305 25.9748
G-401 CTRP2 2.1918 5.6381 1.9435 26.5179
Rh41 CTRP2 2.2797 3.4651 2.2787 25.084
Tm87-16 CTRP2 2.3898 4.0809 2.3765 24.3919
MES-SA CTRP2 2.3902 4.5145 2.347 24.4902
TE 617.T CTRP2 2.5448 7.3779 1.793 25.9542
Hs 729.T CTRP2 2.9724 5.7246 2.7734 21.1545
GCT CTRP2 3.1498 4.5891 3.1342 19.3366
RD CTRP2 3.1738 6.2307 2.8588 20.2315
BT-16 CTRP2 3.4771 5.5752 3.3554 17.5222
Rh18 CTRP2 4.1535 5.5799 4.0866 12.826
KYM-1 CTRP2 4.2606 5.7854 4.1618 12.2245
BT-12 CTRP2 4.7107 5.1223 4.7104 8.8861
HT-1080 CTRP2 5.0948 6.6073 4.8141 7.3561
SK-UT-1 CTRP2 5.1922 10.587 3.0289 14.3711
SK-LMS-1 CTRP2 5.2117 7.8568 4.3763 8.8035
RKN CTRP2 5.4278 6.0495 5.3701 4.3096
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 5.2158 7.3219 4.63 7.7653
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MPP 89 CTRP2 2.3539 3.4764 2.3532 24.5888
MSTO-211H CTRP2 2.6491 4.3189 2.6318 22.678
NCI-H28 CTRP2 2.9539 5.3761 2.8278 21.0209
IST-Mes1 CTRP2 3.1136 5.149 3.0384 19.7812
JL-1 CTRP2 3.3556 5.2653 3.2802 18.1699
ACC-MESO-1 CTRP2 3.4472 5.1854 3.39 17.4969
NCI-H2452 CTRP2 4.1384 5.3873 4.1 12.8279
NCI-H2052 CTRP2 4.7538 7.4215 3.6058 7.1055
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
22Rv1 CTRP2 4.6215 7.135 4.1007 11.4098
VCaP CTRP2 4.6386 10.0704 2.7664 16.6887
DU145 CTRP2 4.8962 7.9412 4.0263 10.9942
LNCaP clone FGC CTRP2 4.9877 11.0089 2.6346 16.3997
PaCa-3 CTRP2 5.9968 7.9635 5.0449 4.2942
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 0.8088 1.3305 0.8088 34.8802
A-253 CTRP2 5.6167 6.4602 5.4229 3.5754
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 CTRP2 -1.4339 2.6625 -1.5002 49.8275
SNU-620 CTRP2 0.9571 3.6286 0.9206 34.0126
HGC-27 CTRP2 1.6351 4.5782 1.539 29.698
GSS CTRP2 1.8542 4.0889 1.8217 28.0247
SNU-1 CTRP2 1.9227 4.9934 1.7835 27.9305
Fu97 CTRP2 2.1449 3.4312 2.1367 20.7251
IM95 CTRP2 2.4583 6.1375 2.1049 25.1181
OCUM-1 CTRP2 2.6312 6.0194 2.3263 23.7996
ECC10 CTRP2 2.884 4.7646 2.8424 21.1953
LMSU CTRP2 2.9311 5.4322 2.7922 21.2181
SNU-668 CTRP2 3.3306 5.2031 3.2628 18.3099
SNU-5 CTRP2 3.7134 5.4569 3.6334 15.8027
HuG1-N CTRP2 3.8149 6.8141 3.3649 16.4744
KATO III CTRP2 3.8996 11.4273 1.408 23.5378
GSU CTRP2 4.0927 5.3303 4.0585 13.1181
KE-39 CTRP2 4.3396 5.8546 4.2321 11.7296
Hs 746.T CTRP2 4.4447 6.4362 4.1778 11.6117
ECC12 CTRP2 4.5294 5.9669 4.4115 10.5034
NCI-N87 CTRP2 4.5307 5.8251 4.4467 10.3742
NUGC-4 CTRP2 4.7546 5.7292 4.7086 8.7498
SNU-216 CTRP2 4.7925 5.981 4.6949 8.6799
23132/87 CTRP2 4.8663 5.865 4.8029 8.0674
SNU-719 CTRP2 5.0182 7.3097 4.436 9.0434
AGS CTRP2 5.1142 6.052 5.0271 6.5021
NUGC-3 CTRP2 5.131 5.9778 5.0649 6.3149
SNU-601 CTRP2 5.1891 6.39 4.9982 6.3893
SH-10-TC CTRP2 5.2896 9.7988 3.5062 12.2077
MKN74 CTRP2 5.3546 6.9353 4.9452 6.1509
MKN1 CTRP2 5.4535 12.6092 2.2574 16.839
MKN7 CTRP2 5.7434 6.7232 5.4302 3.2282
MKN45 CTRP2 7.1152 8.527 5.541 0.7407
SNU-685 CTRP2 4.441 7.9922 3.5443 14.0754
SNU-1077 CTRP2 4.5585 6.1515 4.3923 10.4846
SNG-M CTRP2 4.8451 5.8721 4.7782 8.2207
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 1.2661 4.2461 1.1883 32.0918
CGTH-W-1 CTRP2 2.2836 4.1475 2.2636 25.1219
FTC-238 CTRP2 2.8862 5.2951 2.7696 21.4387
TT2609-C02 CTRP2 3.4265 7.9214 2.5217 20.7534
BHT-101 CTRP2 3.6552 5.0222 3.629 16.0051
ML-1 [Human leukemia] CTRP2 3.8658 6.2261 3.6148 15.3989
8505C CTRP2 3.8871 5.4789 3.8169 14.6118
B-CPAP CTRP2 4.0597 5.742 3.9529 13.5907
TT CTRP2 4.124 5.1827 4.1065 12.8527
CAL-62 CTRP2 4.2652 5.5656 4.2094 12.0437
8305C CTRP2 4.2779 5.2357 4.263 11.8188
FTC-133 CTRP2 6.7217 9.3278 4.9272 3.5389
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BICR 18 CTRP2 2.1662 4.7514 2.0822 26.1213
YD-10B CTRP2 2.3211 4.9032 2.2261 25.1275
YD-8 CTRP2 2.9846 4.6739 2.9564 20.4794
SNU-46 CTRP2 3.2865 4.472 3.28 18.3954
PE/CA-PJ49 CTRP2 3.3793 7.0858 2.7973 19.853
BICR 31 CTRP2 3.3909 5.5559 3.2658 18.1077
CAL-27 CTRP2 3.5795 6.8381 3.1024 18.1361
SCC-4 CTRP2 3.6733 5.3751 3.604 16.0326
BHY CTRP2 4.1617 5.6975 4.073 12.8477
BICR 16 CTRP2 4.1749 5.5537 4.1141 12.6624
SNU-1214 CTRP2 4.2247 6.4452 3.9362 13.1522
Detroit 562 CTRP2 4.3155 6.1236 4.1354 12.1506
SCC-9 CTRP2 4.4671 7.6762 3.71 13.3522
SNU-1041 CTRP2 4.5349 5.6925 4.4781 10.2508
HSC-3 CTRP2 4.5795 5.9253 4.4766 10.1165
SNU-899 CTRP2 4.6169 5.5635 4.5866 9.6131
BICR 6 CTRP2 4.6443 8.136 3.6851 12.9955
BICR 22 CTRP2 4.6608 7.2259 4.1039 11.2918
HSC-4 CTRP2 4.7062 5.9669 4.6044 9.2696
SNU-1076 CTRP2 4.7608 6.5391 4.483 9.556
CAL-33 CTRP2 4.9622 6.4259 4.7409 8.0076
PE/CA-PJ15 CTRP2 5.1158 11.1245 2.6943 15.8776
HSC-2 CTRP2 5.3055 9.5147 3.6607 11.5359
PE/CA-PJ41 (clone D2) CTRP2 5.3869 6.3702 5.2175 4.9975
BICR 56 CTRP2 5.6846 7.1625 5.163 4.463
SNU-1066 CTRP2 5.814 7.1108 5.3088 3.5675
FaDu CTRP2 5.8982 10.1498 3.8686 9.4259
PE/CA-PJ34 (clone C12) CTRP2 6.7888 15.3752 1.9839 15.2261
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-1 CTRP2 1.7246 6.2146 1.2826 30.2583
JMSU-1 CTRP2 1.8111 3.4108 1.8067 28.2175
5637 CTRP2 2.2108 5.0038 2.0919 25.9441
RT-112 CTRP2 2.374 4.5061 2.3308 24.5982
TCCSUP CTRP2 3.2238 5.074 3.1667 18.9844
J82 CTRP2 3.56 7.5572 2.8098 19.294
U-BLC1 CTRP2 3.5743 5.613 3.4531 16.8729
647V CTRP2 3.939 7.2313 3.3408 16.215
253J CTRP2 3.9444 5.1811 3.9181 14.079
639V CTRP2 4.0612 5.4017 4.0156 13.367
BFTC-905 CTRP2 4.2378 5.152 4.2272 12.0714
VM-CUB-1 CTRP2 4.4498 6.8991 4.014 12.2161
BC-3C CTRP2 4.5489 6.4712 4.2787 10.9325
T24 CTRP2 4.5957 6.801 4.2075 11.0687
CAL-29 CTRP2 4.6773 5.5793 4.6489 9.2041
KU-19-19 CTRP2 4.7638 6.4255 4.5269 9.3821
253J-BV CTRP2 4.8353 6.1268 4.7015 8.5263
KMBC-2 CTRP2 4.8353 6.3582 4.6276 8.7985
SW1710 CTRP2 5.0137 6.1221 4.8974 7.2763
UM-UC-3 CTRP2 5.06 6.2616 4.9038 7.1155
SCaBER CTRP2 5.0684 10.1218 3.1445 14.1797
RT-4 CTRP2 5.2829 7.8014 4.4717 8.2438
HT-1376 CTRP2 5.3551 7.5713 4.651 7.3387
HT-1197 CTRP2 5.5005 6.0248 5.4561 3.7781
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 2.7329 4.2214 2.7228 22.0956

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5691).
2 KW-2449, a novel multikinase inhibitor, suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutated BCR/ABL translocation. Blood. 2009 Aug 20;114(8):1607-17.