Details of the Drug

General Information of Drug (ID: DMFP8WE)

Drug Name
ZM-447439
Synonyms
331771-20-1; ZM-447439; ZM447439; ZM 447439; N-[4-[[6-METHOXY-7-[3-(4-MORPHOLINYL)PROPOXY]-4-QUINAZOLINYL]AMINO]PHENYL]BENZAMIDE; TCMDC-125873; UNII-RSN3P9776R; CHEMBL202721; RSN3P9776R; N-(4-((6-methoxy-7-(3-morpholinopropoxy)quinazolin-4-yl)amino)phenyl)benzamide; C29H31N5O4; N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinazolin-4-yl}amino)phenyl]benzamide; N-(4-{[6-Methoxy-7-(3-Morpholin-4-Ylpropoxy)quinazolin-4-Yl]amino}phenyl)benzamide
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 1 Molecular Weight (mw) 513.6
Logarithm of the Partition Coefficient (xlogp) 4.2
Rotatable Bond Count (rotbonds) 10
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 8
Chemical Identifiers
Formula
C29H31N5O4
IUPAC Name
N-[4-[[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]phenyl]benzamide
Canonical SMILES
COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)NC(=O)C4=CC=CC=C4)OCCCN5CCOCC5
InChI
InChI=1S/C29H31N5O4/c1-36-26-18-24-25(19-27(26)38-15-5-12-34-13-16-37-17-14-34)30-20-31-28(24)32-22-8-10-23(11-9-22)33-29(35)21-6-3-2-4-7-21/h2-4,6-11,18-20H,5,12-17H2,1H3,(H,33,35)(H,30,31,32)
InChIKey
OGNYUTNQZVRGMN-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
9914412
ChEBI ID
CHEBI:91376
CAS Number
331771-20-1
TTD ID
D0QC0W
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Aurora kinase A (AURKA) TTPS3C0 AURKA_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Aurora kinase B (AURKB) OTIY4VHU AURKB_HUMAN Protein Interaction/Cellular Processes [3]
Neurogenic locus notch homolog protein 1 (NOTCH1) OTI1WADQ NOTC1_HUMAN Gene/Protein Processing [4]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Aurora kinase A (AURKA) DTT AURKA 9.41E-46 -1.78 -2.05
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 2.4552 4.3687 1.9733 11.4458
ES8 GDSC1; GDSC2 -0.5627 1.39 -0.5849 39.0852
ES7 GDSC1; GDSC2 -0.297 1.5455 -0.3191 36.4238
EW-12 GDSC2 0.0645 2.3777 -0.0269 33.1392
SK-ES-1 GDSC1; GDSC2 0.6336 3.5987 0.3081 28.6479
MHH-ES-1 GDSC1; GDSC2 0.7681 3.1954 0.5684 26.6619
TC-71 GDSC1; GDSC2 1.0451 3.0733 0.9004 23.6002
ES5 GDSC1; GDSC2 1.051 4.2214 0.5506 25.4465
ES1 GDSC1; GDSC2 1.2252 4.2628 0.7222 23.7461
EW-22 GDSC1; GDSC2 1.2286 3.696 0.9254 22.6203
A-673 GDSC1; GDSC2 1.3809 4.1313 0.9382 21.8741
SK-PN-DW GDSC1; GDSC2 1.4351 4.9406 0.6725 23.1129
EW-16 GDSC1; GDSC2 1.7902 6.1153 0.5077 22.5657
CADO-ES1 GDSC1; GDSC2 1.8597 3.4135 1.7002 15.5189
EW-7 GDSC1; GDSC2 2.3054 3.6992 2.0907 11.3694
EW-18 GDSC1; GDSC2 2.3928 7.1221 0.6012 19.8103
CHSA0011 GDSC1; GDSC2 2.4105 3.7034 2.2021 10.2836
EW-1 GDSC1; GDSC2 2.4501 3.5114 2.3127 9.4871
CAL-72 GDSC1; GDSC2 2.5786 6.3578 1.1473 16.013
EW-11 GDSC1; GDSC2 2.7335 4.0939 2.3789 7.9358
CHSA8926 GDSC1; GDSC2 2.7618 3.5004 2.654 6.2052
SaOS-2 GDSC1; GDSC2 2.8129 5.8923 1.5912 12.517
ES4 GDSC1; GDSC2 2.9148 5.1936 2.0283 9.4553
SJSA-1 GDSC1; GDSC2 3.2491 5.2408 2.3012 6.6774
HOS GDSC1; GDSC2 3.4128 5.4111 2.3521 5.6778
CAL-78 GDSC1; GDSC2 3.4229 5.1449 2.4931 4.9613
HuO-3N1 GDSC1; GDSC2 3.4956 5.47 2.389 5.4207
EW-3 GDSC1; GDSC2 3.5391 7.1487 1.5863 10.3401
EW-24 GDSC1; GDSC2 3.5706 5.2868 2.5383 4.2839
U-CH2 GDSC2 3.5822 6.1296 2.1287 6.8297
CHSA0108 GDSC1; GDSC2 3.6247 7.806 1.3269 11.6919
HuO9 GDSC1; GDSC2 3.7032 6.4665 2.055 6.9759
ES6 GDSC1; GDSC2 3.9642 5.8625 2.5388 3.3723
EW-13 GDSC1; GDSC2 4.0334 8.9084 1.0972 11.9675
G-292 clone A141B1 GDSC1; GDSC2 4.0826 6.6427 2.2448 4.8987
NY GDSC1; GDSC2 4.0993 7.6566 1.7634 7.8035
H-EMC-SS GDSC1; GDSC2 4.6927 8.1338 1.9399 5.4637
NOS-1 [Human HNSCC] GDSC1; GDSC2 4.9093 8.6997 1.8128 5.7843
MG-63 GDSC1; GDSC2 4.9365 7.5215 2.366 2.5749
U2OS GDSC1; GDSC2 5.4387 13.0251 0.1012 13.5801
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 168 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1; GDSC2 1.211 3.5185 0.9616 22.5028
EoL-1 GDSC1; GDSC2 -1.2598 0.6153 -1.2677 46.0026
MOLT-16 GDSC1; GDSC2 -1.2035 -0.5328 -1.2035 45.4129
Kasumi-1 GDSC2 -1.0541 0.1407 -1.0545 43.9159
ALL-SIL GDSC1; GDSC2 -1.0421 0.8137 -1.0517 43.8304
Karpas-45 GDSC1; GDSC2 -1.017 0.0346 -1.0172 43.5425
RS4;11 GDSC1; GDSC2 -1.0067 0.3532 -1.0078 43.4428
P12-Ichikawa GDSC1 -0.9327 0.2131 -0.9365 36.6824
MOLM-13 GDSC1; GDSC2 -0.8802 1.3487 -0.9119 42.2944
SIG-M5 GDSC2 -0.8584 -0.3432 -0.8584 41.9498
NALM-6 GDSC1; GDSC2 -0.816 2.3461 -0.9699 42.0677
RPMI-8402 GDSC1; GDSC2 -0.7923 1.7433 -0.8559 41.5376
697 GDSC1; GDSC2 -0.6205 0.5022 -0.621 39.5654
CRO-AP2 GDSC1; GDSC2 -0.604 1.962 -0.6823 39.7297
SU-DHL-5 GDSC1; GDSC2 -0.5622 1.0763 -0.5704 39.0167
MOLT-13 GDSC1; GDSC2 -0.4015 0.5613 -0.4017 37.3657
MV4-11 GDSC1; GDSC2 -0.3521 2.0723 -0.4284 37.2221
KE-37 GDSC1; GDSC2 -0.2949 1.1993 -0.3015 36.328
EM-2 GDSC1; GDSC2 -0.2833 2.2029 -0.3732 36.5977
P31/FUJ GDSC1; GDSC2 -0.2684 2.4772 -0.4022 36.6426
OCI-AML-5 GDSC1; GDSC2 -0.26 1.554 -0.2813 36.0486
CCRF-CEM GDSC1; GDSC2 -0.2582 1.7506 -0.294 36.0997
MOLT-4 GDSC1; GDSC2 -0.2269 1.6824 -0.2557 35.7532
BV-173 GDSC1; GDSC2 -0.2136 3.3958 -0.5569 36.9658
BC-3 GDSC2 -0.2028 1.6584 -0.2288 35.4982
BE-13 GDSC1; GDSC2 -0.1774 3.1204 -0.4439 36.311
P32/ISH GDSC1; GDSC2 -0.1469 1.4036 -0.1572 34.8612
SU-DHL-10 GDSC1; GDSC2 -0.1323 1.4934 -0.1461 34.7323
RCH-ACV GDSC1; GDSC2 -0.1187 2.2868 -0.2093 34.9628
ALL-PO GDSC1; GDSC2 -0.0678 1.7866 -0.0977 34.1642
MOLM-16 GDSC1; GDSC2 0.0692 2.5123 -0.0441 33.198
DoHH2 GDSC1; GDSC2 0.0899 1.3153 0.0866 32.4502
P30/OHK GDSC1; GDSC2 0.1001 1.43 0.0942 32.3611
Karpas-231 GDSC1; GDSC2 0.1713 2.058 0.1286 31.8305
SUP-M2 GDSC1; GDSC2 0.1718 2.631 0.0451 32.2404
OCI-Ly7 GDSC1; GDSC2 0.2112 1.4283 0.2072 31.2365
BL-41 GDSC1; GDSC2 0.2312 2.7534 0.0854 31.7417
SR GDSC1; GDSC2 0.261 2.1415 0.2145 30.9505
ATN-1 GDSC1; GDSC2 0.2906 3.6385 -0.0778 32.2192
Loucy GDSC1; GDSC2 0.3009 2.0905 0.2619 30.5128
JeKo-1 GDSC1; GDSC2 0.4215 4.5151 -0.234 32.2659
KOPN-8 GDSC1; GDSC2 0.4306 3.2567 0.1841 30.2577
ST486 GDSC1; GDSC2 0.499 3.5141 0.1866 29.9093
MHH-CALL-4 GDSC2 0.6269 5.3767 -0.3549 31.7871
SUP-B15 GDSC1; GDSC2 0.6336 3.0458 0.4586 27.8761
Ramos.2G6.4C10 GDSC1; GDSC2 0.6435 2.8642 0.51 27.5629
OCI-Ly19 GDSC1; GDSC2 0.6987 2.252 0.6649 26.4956
TALL-1 [Human adult T-ALL] GDSC2 0.7041 4.766 -0.0273 29.9553
NOMO-1 GDSC1; GDSC2 0.7226 4.059 0.2545 28.4945
CTB-1 GDSC1; GDSC2 0.7458 4.2978 0.1945 28.6853
NU-DUL-1 GDSC1; GDSC2 0.8157 3.0781 0.6493 26.0116
WSU-NHL GDSC1; GDSC2 0.8323 3.457 0.5669 26.3664
VAL GDSC1; GDSC2 0.9015 3.5493 0.615 25.789
LC4-1 GDSC1; GDSC2 0.9214 4.6089 0.2653 27.5167
CTV-1 GDSC1; GDSC2 1.0041 3.7682 0.6579 25.087
NB4 GDSC1; GDSC2 1.0046 3.0941 0.8514 24.0511
SUP-B8 GDSC1; GDSC2 1.0397 3.0607 0.8974 23.6416
SKM-1 GDSC1; GDSC2 1.0693 5.1834 0.1886 27.2361
BONNA-12 GDSC2 1.0901 4.6065 0.4456 25.8262
H9 GDSC1; GDSC2 1.1249 4.0678 0.686 24.3887
HL-60 GDSC1; GDSC2 1.1453 3.1027 1.0026 22.5862
ML-2 GDSC1; GDSC2 1.2918 4.3333 0.7666 23.2115
A4/Fukuda GDSC1; GDSC2 1.3253 5.5349 0.3026 25.5466
Reh GDSC1; GDSC2 1.3303 4.6109 0.6984 23.4183
SU-DHL-16 GDSC1; GDSC2 1.3325 4.9623 0.5562 24.1803
QIMR-WIL GDSC1; GDSC2 1.3843 4.6207 0.7514 22.895
RPMI-8226 GDSC1; GDSC2 1.3901 4.583 0.7728 22.7516
MY-M12 GDSC1; GDSC2 1.4088 4.193 0.9451 21.7143
Daudi GDSC1; GDSC2 1.4896 3.1721 1.3611 19.0588
DEL GDSC1; GDSC2 1.4929 3.6991 1.2115 19.8618
GA-10 GDSC1; GDSC2 1.502 3.8908 1.1558 20.1315
LAMA-84 GDSC1; GDSC2 1.5225 6.6119 0.0119 26.177
BC-1 GDSC1; GDSC2 1.5567 3.3713 1.3818 18.6376
L-540 GDSC1; GDSC2 1.5609 4.7407 0.8877 21.3893
L-363 GDSC1; GDSC2 1.6118 5.127 0.7754 21.8085
PL-21 GDSC1; GDSC2 1.6353 5.4251 0.6678 22.3099
OCI-AML-2 GDSC1; GDSC2 1.6837 3.6282 1.442 17.7343
JURL-MK1 GDSC1; GDSC2 1.6868 5.1822 0.8282 21.2066
GR-ST GDSC1; GDSC2 1.7032 4.9837 0.9319 20.5526
Farage GDSC1; GDSC2 1.7447 4.0499 1.3586 17.9387
JSC-1 GDSC1; GDSC2 1.7464 4.7643 1.071 19.5812
Ku812 GDSC1; GDSC2 1.7675 5.7084 0.6731 21.7504
AMO1 GDSC1; GDSC2 1.7868 3.8921 1.4624 17.1686
YT GDSC1; GDSC2 1.794 5.6066 0.7463 21.2374
JVM-2 GDSC1; GDSC2 1.8881 4.6961 1.2471 17.9877
A3/Kawakami GDSC1; GDSC2 1.8935 3.214 1.7911 14.87
DB GDSC1; GDSC2 1.9592 6.13 0.6668 21.0388
DG-75 GDSC1; GDSC2 1.9972 3.7561 1.7381 14.6984
Mono-Mac-6 GDSC1; GDSC2 2.0157 6.6818 0.4592 21.9596
SU-DHL-4 GDSC1; GDSC2 2.0765 3.1172 2.0127 12.8289
KCL-22 GDSC1; GDSC2 2.0823 3.3574 1.9592 13.0901
DND-41 GDSC1; GDSC2 2.0881 4.8179 1.3994 16.2993
PF-382 GDSC1; GDSC2 2.0901 3.7673 1.8343 13.7521
MEG-01 GDSC1; GDSC2 2.1012 6.4523 0.6512 20.5901
JJN-3 GDSC1; GDSC2 2.1082 3.3529 1.9887 12.8112
SUP-T1 GDSC1; GDSC2 2.1437 3.775 1.8891 13.2102
HDLM-2 GDSC1; GDSC2 2.1595 7.0713 0.4081 21.6987
NCI-H929 GDSC1; GDSC2 2.1879 5.1889 1.3316 16.3177
RPMI-6666 GDSC1; GDSC2 2.2303 4.7032 1.5952 14.5804
SU-DHL-8 GDSC1; GDSC2 2.2327 4.3713 1.7435 13.6894
CML-T1 GDSC1; GDSC2 2.2382 3.5641 2.0652 11.8056
KMS-11 GDSC1; GDSC2 2.2454 3.7727 1.9991 12.1477
KY821 GDSC1; GDSC2 2.2576 5.3416 1.3296 16.0681
WSU-DLCL2 GDSC1; GDSC2 2.265 3.4286 2.1377 11.2834
RPMI-8866 GDSC1; GDSC2 2.281 6.2034 0.9427 18.2709
MHH-PREB-1 GDSC1; GDSC2 2.312 3.3876 2.2011 10.7227
SU-DHL-6 GDSC1; GDSC2 2.3321 4.9144 1.6018 14.1521
NK-92MI GDSC2 2.3494 3.8409 2.0845 11.2176
Karpas-422 GDSC1; GDSC2 2.3639 4.7634 1.7028 13.4226
MOLP-8 GDSC1; GDSC2 2.3702 5.4377 1.3945 15.2625
OCI-AML-3 GDSC1 2.442 7.5533 -0.4174 16.7621
U266B1 GDSC1; GDSC2 2.4523 8.2959 0.0777 22.3582
BALL-1 GDSC1; GDSC2 2.4605 5.5685 1.4192 14.7872
JVM-3 GDSC1; GDSC2 2.4769 8.4097 0.0435 22.4427
HAL-01 GDSC1; GDSC2 2.5338 4.553 1.9693 11.1691
IM-9 GDSC1; GDSC2 2.5685 3.8043 2.3316 8.8739
Karpas-299 GDSC1; GDSC2 2.6051 4.2592 2.1745 9.6584
Granta-519 GDSC1; GDSC2 2.6176 4.0073 2.2983 8.8703
HC-1 GDSC1; GDSC2 2.6696 5.1482 1.821 11.5835
KG-1 GDSC1; GDSC2 2.6912 7.5196 0.6768 18.363
OCI-M1 GDSC1; GDSC2 2.6999 3.424 2.6127 6.7083
CMK GDSC1 2.7091 4.9153 1.0826 5.0325
CA46 GDSC1; GDSC2 2.7262 3.5899 2.5831 6.7613
Namalwa GDSC1; GDSC2 2.7531 5.4771 1.7401 11.7954
L-428 GDSC1; GDSC2 2.8004 3.7374 2.603 6.3373
MC116 GDSC1; GDSC2 2.8151 3.2316 2.7906 5.2129
HH [Human lymphoma] GDSC1; GDSC2 2.8313 5.4071 1.8468 10.8679
EHEB GDSC1 2.842 7.4392 -0.0537 13.0119
Karpas-1106P GDSC1; GDSC2 2.8464 5.3309 1.898 10.4982
KMOE-2 GDSC1; GDSC2 2.8841 8.7225 0.2487 20.0406
GDM-1 GDSC1; GDSC2 2.9503 4.1779 2.5552 6.0555
Jurkat GDSC1; GDSC2 3.0266 4.4028 2.5192 6.0114
NKM-1 GDSC1; GDSC2 3.0418 11.2991 -0.9024 24.8098
SUP-HD1 GDSC1; GDSC2 3.1046 5.5729 2.0105 8.9554
OPM-2 GDSC1; GDSC2 3.1061 5.3181 2.1387 8.1426
ARH-77 GDSC1; GDSC2 3.1862 6.0468 1.8448 9.7475
RL GDSC1; GDSC2 3.1988 4.37 2.692 4.3611
VL51 GDSC1; GDSC2 3.247 5.772 2.0339 8.3733
EB2 GDSC1; GDSC2 3.2654 4.9575 2.4565 5.6458
HEL GDSC1; GDSC2 3.2887 6.6757 1.6172 10.8658
U-698-M GDSC1; GDSC2 3.3023 6.6566 1.6382 10.6952
KMS-12-BM GDSC2 3.3643 6.8929 1.5716 10.9276
WIL2 NS GDSC1; GDSC2 3.3959 4.8416 2.6228 4.2157
KM-H2 GDSC1; GDSC2 3.433 9.1974 0.4762 17.1375
SU-DHL-1 GDSC2 3.4605 6.1486 2.0224 7.8306
Raji GDSC1; GDSC2 3.4643 5.1914 2.503 4.7858
L-1236 GDSC1; GDSC2 3.6008 5.5838 2.4141 4.9863
HT GDSC1; GDSC2 3.6456 5.3321 2.5722 3.8848
THP-1 GDSC1; GDSC2 3.6599 5.3494 2.5742 3.8372
Jiyoye GDSC1; GDSC2 3.6729 6.4167 2.0564 7.045
CESS GDSC1; GDSC2 3.7068 5.8042 2.3851 4.9018
ROS-50 GDSC1; GDSC2 3.7349 6.2831 2.1698 6.177
EJM GDSC1; GDSC2 3.7638 5.9597 2.3507 4.9774
MM1.S GDSC1; GDSC2 3.7808 6.9539 1.8727 7.9143
TK [Human B-cell lymphoma] GDSC1; GDSC2 3.8199 7.2754 1.7433 8.617
Hs 445 GDSC2 3.8247 9.5619 0.6104 15.2893
Karpas-620 GDSC1; GDSC2 3.9964 9.4616 0.7944 13.8021
K-562 GDSC1; GDSC2 3.9992 6.6186 2.1982 5.3688
SCC-3 GDSC2 4.0013 8.7557 1.1484 11.7509
RC-K8 GDSC1 4.0668 5.2526 1.6201 0.1449
MHH-CALL-2 GDSC1 4.1527 5.8114 1.4553 0.5298
MN-60 GDSC1; GDSC2 4.2059 7.6776 1.8296 7.1507
LP-1 GDSC1; GDSC2 4.3127 6.5707 2.4302 3.3316
Sc-1 GDSC1 4.3339 5.9786 1.4648 0.4051
ME1 GDSC1; GDSC2 4.4275 7.0274 2.2896 3.9332
TUR GDSC1; GDSC2 4.5622 11.0652 0.4291 14.3444
MLMA GDSC1; GDSC2 4.6819 8.2461 1.8801 5.8345
SK-MM-2 GDSC1; GDSC2 5.6085 7.3686 2.7439 0.4502
⏷ Show the Full List of 168 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACP4 C GDSC1; GDSC2 1.1979 3.041 1.0741 21.9581
KYSE-220 GDSC1; GDSC2 1.8855 4.3678 1.3825 17.2117
TE-12 GDSC1; GDSC2 2.7033 6.8629 1.0127 16.389
KYSE-50 GDSC1; GDSC2 2.7286 6.039 1.442 13.7178
FLO-1 GDSC1; GDSC2 3.2029 7.5518 1.1071 14.2364
OACM5.1 C GDSC1; GDSC2 3.7681 5.5994 2.5302 3.8552
ESO-51 GDSC1; GDSC2 3.8617 10.0828 0.3801 16.428
KYAE-1 GDSC1; GDSC2 3.9775 7.7748 1.6154 9.0048
SK-GT-4 GDSC1; GDSC2 4.031 7.5743 1.7538 8.0259
HCE-4 GDSC1; GDSC2 4.0385 7.3454 1.8717 7.2844
ESO-26 GDSC1; GDSC2 4.3902 7.3975 2.0909 5.1759
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2 5.4721 13.014 0.1298 13.754
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-14 GDSC1; GDSC2 -0.4628 1.8187 -0.5156 38.2214
CHP-134 GDSC1 0.3267 2.6348 -0.0318 23.3153
KP-N-YS GDSC1; GDSC2 0.5476 3.62 0.2079 29.5668
CHP-212 GDSC1; GDSC2 0.9339 3.6417 0.622 25.6016
SJNB-17 GDSC1; GDSC2 1.0542 3.7109 0.7309 24.4664
IMR-5 GDSC1; GDSC2 1.1629 3.4199 0.9383 22.8494
Kelly GDSC1; GDSC2 1.2585 2.539 1.2256 20.8744
NB69 GDSC1; GDSC2 1.2984 3.7973 0.9676 22.0756
MHH-NB-11 GDSC1; GDSC2 1.3342 3.2157 1.1808 20.7505
SJNB-5 GDSC1; GDSC2 1.3756 3.1511 1.242 20.2291
NH-12 GDSC1; GDSC2 1.4115 3.5407 1.1734 20.4368
SJNB-13 GDSC1; GDSC2 1.5152 4.0311 1.1195 20.2779
SJNB-10 GDSC1; GDSC2 1.5907 3.5223 1.3742 18.5253
NB1 GDSC1; GDSC2 1.6296 4.0835 1.2228 19.2022
TGW GDSC1; GDSC2 1.6866 3.7236 1.4134 17.8808
GOTO GDSC1; GDSC2 1.7377 4.8236 1.0366 19.1366
KP-N-RT-BM-1 GDSC2 2.0292 4.5912 1.4382 16.3031
SJNB-6 GDSC1; GDSC2 2.0378 4.0688 1.6639 14.95
SK-N-SH GDSC1; GDSC2 2.0471 3.8501 1.7576 14.3727
SJNB-7 GDSC1; GDSC2 2.0674 6.751 0.4755 21.6783
SiMa GDSC1; GDSC2 2.2695 4.3159 1.8053 13.1766
SK-N-MC-IXC GDSC1; GDSC2 2.3352 3.3477 2.2379 10.4161
SK-N-BE(2)-M17 GDSC1; GDSC2 2.4145 5.2593 1.5221 14.3286
NB(TU)1 GDSC1; GDSC2 2.5618 5.664 1.4697 14.1213
LA-N-6 GDSC1; GDSC2 2.7776 4.3396 2.3102 8.1866
KP-N-YN GDSC1; GDSC2 2.9618 7.819 0.7666 16.9715
GI-ME-N GDSC1; GDSC2 2.9702 5.0665 2.1416 8.562
SJNB-12 GDSC1 3.0663 6.3809 0.6218 7.5141
SK-N-AS GDSC1; GDSC2 3.0681 6.456 1.5386 11.6126
SK-N-FI GDSC1; GDSC2 3.2097 4.6153 2.5795 5.0375
SK-N-DZ GDSC1; GDSC2 3.3441 4.7607 2.6209 4.3747
CHP-126 GDSC1; GDSC2 3.9956 8.165 1.4363 10.0479
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1; GDSC2 4.1079 9.5595 0.8315 13.3007
Cancer Drug Sensitivity Data Curated from 52 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-148 GDSC2 0.8967 3.483 0.6296 25.6445
OCUB-M GDSC1; GDSC2 1.1206 4.471 0.5309 25.1534
HCC1187 GDSC1; GDSC2 1.1368 3.503 0.8855 23.1731
COLO 824 GDSC1; GDSC2 1.2577 5.3656 0.3067 25.7292
HCC2157 GDSC1; GDSC2 1.5449 3.1523 1.4262 18.4524
Hs 578T GDSC1; GDSC2 1.8748 5.9332 0.6761 21.2417
MDA-MB-468 GDSC1; GDSC2 1.9431 4.497 1.389 16.8785
HCC1569 GDSC1; GDSC2 2.085 4.1548 1.6795 14.6129
HCC70 GDSC1; GDSC2 2.3934 5.7015 1.2912 15.7469
Evsa-T GDSC1; GDSC2 2.5112 5.3077 1.5928 13.5009
HCC1806 GDSC1; GDSC2 2.5344 4.8562 1.8291 11.9778
DU4475 GDSC1; GDSC2 2.5623 5.4195 1.5882 13.3481
JIMT-1 GDSC1; GDSC2 2.6588 3.777 2.4379 7.8549
HCC1395 GDSC1; GDSC2 2.763 4.1674 2.3753 7.5733
HCC1954 GDSC1; GDSC2 2.8385 4.2478 2.413 7.3082
MRK-nu-1 GDSC1; GDSC2 2.9993 6.679 1.3675 13.247
HCC1143 GDSC1; GDSC2 3.0649 6.8425 1.3431 13.1911
HCC1937 GDSC1; GDSC2 3.0685 4.8867 2.3195 6.8778
AU565 GDSC1; GDSC2 3.0858 5.4201 2.0701 8.6091
YMB-1-E GDSC2 3.1594 5.9344 1.8779 9.6213
HDQ-P1 GDSC1; GDSC2 3.2397 5.4078 2.2098 7.2584
CAL-85-1 GDSC1; GDSC2 3.3071 4.6921 2.6244 4.4437
BT-20 GDSC1; GDSC2 3.3186 6.2897 1.8353 9.3808
HCC1500 GDSC1; GDSC2 3.3617 4.6787 2.6763 3.9595
MDA-MB-453 GDSC1; GDSC2 3.3683 5.5334 2.2546 6.6006
HCC1599 GDSC2 3.4184 6.7351 1.6951 9.9694
MDA-MB-330 GDSC1; GDSC2 3.4987 6.6193 1.8181 9.0087
MFM-223 GDSC1; GDSC2 3.5719 5.385 2.4906 4.564
BT-549 GDSC1; GDSC2 3.5872 7.7688 1.3155 11.8253
HCC1419 GDSC1; GDSC2 3.7375 8.0127 1.3132 11.4277
MCF-7 GDSC1; GDSC2 3.7566 6.8764 1.8926 7.8253
BT-474 GDSC1; GDSC2 3.8144 6.2123 2.2638 5.3768
EFM-192A GDSC1; GDSC2 3.8988 7.3077 1.787 8.1196
MDA-MB-175-VII GDSC1; GDSC2 3.9286 6.9434 1.9885 6.804
MDA-MB-361 GDSC1; GDSC2 3.9526 8.4859 1.2449 11.2686
MDA-MB-231 GDSC1; GDSC2 3.9878 7.7638 1.6286 8.8683
ZR-75-30 GDSC1; GDSC2 4.0213 6.6015 2.2221 4.9939
CAL-51 GDSC1; GDSC2 4.0861 7.2051 1.9745 6.5195
UACC-812 GDSC2 4.1873 8.0161 1.6511 8.2779
MDA-MB-415 GDSC1; GDSC2 4.2222 6.3065 2.4966 3.1039
EFM-19 GDSC1; GDSC2 4.2871 9.5341 0.9789 11.9703
BT-483 GDSC1; GDSC2 4.2952 8.0131 1.7296 7.5267
UACC-893 GDSC1; GDSC2 4.3112 9.3074 1.1083 10.8432
HCC38 GDSC1; GDSC2 4.4118 8.538 1.5569 8.296
HCC1428 GDSC1; GDSC2 4.4807 7.3927 2.1522 4.6176
MDA-MB-157 GDSC1; GDSC2 4.5289 11.6351 0.1233 15.9467
CAL-120 GDSC1; GDSC2 4.703 6.7787 2.5635 1.9695
T-47D GDSC1; GDSC2 4.9732 10.5351 0.9815 10.3602
HCC2218 GDSC1; GDSC2 4.9911 9.3443 1.5623 7.0405
MDA-MB-436 GDSC1; GDSC2 5.1049 7.1941 2.5926 1.3565
HCC202 GDSC1 5.3487 7.1147 1.4367 0.1546
CAMA-1 GDSC1; GDSC2 5.7419 13.5646 0.0501 13.1912
⏷ Show the Full List of 52 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-172 GDSC1; GDSC2 0.5706 2.5129 0.4952 27.0266
H4 GDSC1; GDSC2 0.6553 2.2921 0.6149 26.9646
D-566MG GDSC1; GDSC2 0.6915 3.2829 0.4618 27.5817
MOG-G-UVW GDSC1; GDSC2 0.9188 4.0378 0.474 26.4525
D-336MG GDSC1; GDSC2 1.5746 4.3152 1.0748 19.5777
SW1088 GDSC1; GDSC2 1.6344 4.8174 0.932 20.1238
SF126 GDSC1; GDSC2 1.7304 3.8864 1.4037 17.7441
SF539 GDSC1; GDSC2 1.7386 3.6079 1.5082 17.1224
SF295 GDSC1; GDSC2 1.8694 3.8676 1.5602 16.2578
D-247MG GDSC1; GDSC2 1.8998 3.5436 1.7042 15.3168
42-MG-BA GDSC1; GDSC2 1.9068 4.1939 1.4754 16.5856
YKG-1 GDSC1; GDSC2 1.9321 4.8352 1.2322 17.8985
LN-18 GDSC1; GDSC2 1.972 3.534 1.7858 14.542
D-245MG GDSC2 1.998 4.6608 1.3759 16.7937
D-502MG GDSC1; GDSC2 2.0171 5.173 1.1679 17.9414
YH-13 GDSC1; GDSC2 2.0564 3.5936 1.8581 13.7648
Hs 683 GDSC1; GDSC2 2.057 4.4098 1.5445 15.5669
8-MG-BA GDSC1; GDSC2 2.0919 3.5589 1.9082 13.3284
M059J GDSC1; GDSC2 2.1707 4.0091 1.8286 13.4433
D-423MG GDSC1; GDSC2 2.2075 5.5671 1.1747 17.1779
D283 Med GDSC1; GDSC2 2.2516 5.1413 1.417 15.5665
GaMG GDSC1; GDSC2 2.335 6.32 0.9377 18.1047
T98G GDSC1; GDSC2 2.3422 5.2276 1.4662 14.9329
GI-1 GDSC1; GDSC2 2.4093 6.6057 0.8689 18.2387
GB-1 GDSC1; GDSC2 2.5042 5.6997 1.3979 14.7608
DK-MG GDSC1; GDSC2 2.5412 3.6101 2.3769 8.7287
CAS-1 GDSC1; GDSC2 2.558 3.3014 2.4937 8.0038
AM-38 GDSC1; GDSC2 2.5638 4.1331 2.1882 9.7376
ONS-76 GDSC1; GDSC2 2.7032 6.5946 1.1451 15.6029
Daoy GDSC1; GDSC2 2.7622 5.1228 1.9211 10.6413
MOG-G-CCM GDSC1; GDSC2 2.7765 5.2621 1.8668 10.9291
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 2.7918 6.1158 1.4619 13.3845
U-251MG GDSC1; GDSC2 2.8094 4.8381 2.1035 9.0228
KINGS-1 GDSC1; GDSC2 2.8507 4.7193 2.2 8.6034
D-542MG GDSC1; GDSC2 2.9178 4.1764 2.5243 6.3623
KALS-1 GDSC1; GDSC2 2.9204 4.5359 2.3547 7.1448
PFSK-1 GDSC1 2.984 6.5004 0.5077 8.5743
D-263MG GDSC1; GDSC2 3.0435 8.0618 0.7161 16.9987
SNB-75 GDSC1; GDSC2 3.1061 5.2854 2.155 8.0403
LNZTA3WT4 GDSC1; GDSC2 3.1566 5.5098 2.0874 8.3095
DBTRG-05MG GDSC1; GDSC2 3.25 6.9705 1.4374 12.0936
KNS-42 GDSC1; GDSC2 3.4524 6.5499 1.8154 9.1549
U-87MG ATCC GDSC1 3.5098 11.7423 -1.6773 20.4095
D-392MG GDSC1; GDSC2 3.5255 6.9324 1.6835 9.7749
SF268 GDSC1; GDSC2 3.6954 6.2759 2.1435 6.4419
SK-MG-1 GDSC1; GDSC2 3.7353 8.3047 1.1661 12.3527
NMC-G1 GDSC1; GDSC2 3.9791 6.8512 2.0705 6.2012
Onda 10 GDSC1; GDSC2 3.9866 7.4798 1.7676 8.0496
U-118MG GDSC1; GDSC2 4.1682 8.3896 1.4541 9.512
KNS-81-FD GDSC1; GDSC2 4.3286 7.3641 2.0657 5.4541
LN-405 GDSC1; GDSC2 4.5844 6.9621 2.4152 2.9439
Onda 11 GDSC1; GDSC2 4.6868 8.8313 1.6049 7.4381
LN-229 GDSC1; GDSC2 4.7245 9.3053 1.403 8.5367
Becker GDSC1; GDSC2 4.8397 8.4176 1.9006 5.4108
SW1783 GDSC1; GDSC2 5.6692 8.8538 2.1805 2.6245
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1; GDSC2 2.6193 3.7817 2.3944 8.2986
TGBC24TKB GDSC1; GDSC2 3.3111 6.6771 1.6353 10.3223
TGBC1TKB GDSC1; GDSC2 5.3922 13.2935 -0.0616 14.8522
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESS-1 GDSC1; GDSC2 1.713 4.4056 1.1854 19.0621
RL95-2 GDSC1; GDSC2 1.7619 5.2754 0.8635 20.7046
MFE-296 GDSC1; GDSC2 2.217 7.0342 0.4802 21.1016
EN GDSC1; GDSC2 2.7558 6.1761 1.3994 13.8879
MFE-280 GDSC1; GDSC2 3.6113 6.2455 2.0937 6.7321
KLE GDSC1; GDSC2 3.6124 6.0786 2.1776 6.4425
AN3-CA GDSC1; GDSC2 3.9062 8.9493 0.9791 12.5711
MFE-319 GDSC1; GDSC2 5.5925 8.7344 2.1916 2.574
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB2241-RCC GDSC1; GDSC2 0.5349 10.0588 -2.5797 38.7452
A-498 GDSC1; GDSC2 1.5231 3.4513 1.322 19.1176
Caki-1 GDSC1; GDSC2 1.7985 3.2059 1.6895 15.3095
RXF 393L GDSC1; GDSC2 1.903 4.1799 1.4769 16.5928
BB65-RCC GDSC1; GDSC2 1.9142 8.1196 -0.3317 26.242
NCC010 GDSC1; GDSC2 2.1954 4.2901 1.7392 13.8641
UO-31 GDSC1; GDSC2 2.3474 3.6547 2.152 10.465
KTCTL-140 GDSC1; GDSC2 2.3728 3.8169 2.1188 10.9214
786-O GDSC1; GDSC2 2.4106 3.5166 2.2682 9.9104
KTCTL-26A GDSC1; GDSC2 2.4134 4.5651 1.8427 12.3913
KTCTL-195 GDSC1; GDSC2 2.5597 3.4575 2.4495 8.2392
LB996-RCC GDSC1; GDSC2 2.7178 7.0333 0.9415 16.2054
KMRC-20 GDSC1; GDSC2 2.8309 4.3006 2.3808 7.5587
SW13 GDSC1; GDSC2 2.8773 4.2744 2.4385 6.7928
BFTC-909 GDSC1; GDSC2 2.8821 6.7397 1.234 13.9921
KTCTL-13 GDSC1; GDSC2 2.972 4.1843 2.5731 5.8672
CAL-54 GDSC1; GDSC2 3.0238 6.0305 1.7118 10.7032
HA7-RCC GDSC1; GDSC2 3.0593 5.4663 2.0237 9.0145
VMRC-RCW GDSC1; GDSC2 3.1428 4.6387 2.5089 5.4967
KTCTL-1M GDSC1; GDSC2 3.1639 4.6282 2.5328 5.4757
OS-RC-2 GDSC1; GDSC2 3.2468 7.0102 1.4149 12.2412
SW156 GDSC1; GDSC2 3.3214 5.0965 2.4342 5.4281
NCC021 GDSC1; GDSC2 3.526 5.3567 2.4692 4.8343
RCC10RGB GDSC1; GDSC2 3.6078 5.4984 2.4618 4.6694
ACHN GDSC1; GDSC2 3.801 6.3432 2.1896 5.6861
A-704 GDSC1; GDSC2 3.8336 6.1805 2.2934 5.1662
LB1047-RCC GDSC1; GDSC2 3.8882 7.3719 1.7473 8.4187
769-P GDSC1; GDSC2 3.9431 6.2202 2.3522 4.3942
TK-10 GDSC1; GDSC2 4.075 7.0709 2.0319 6.2157
VMRC-RCZ GDSC1; GDSC2 4.7257 7.0781 2.4445 2.5634
KTCTL-21 GDSC1; GDSC2 4.7479 10.623 0.7808 12.0106
KMRC-1 GDSC1; GDSC2 5.1354 9.0326 1.7991 5.4462
SN12C GDSC1; GDSC2 5.319 8.881 1.9775 4.0129
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW48 GDSC1; GDSC2 -0.1987 1.7053 -0.228 35.473
HCT 116 GDSC1; GDSC2 1.0528 5.816 -0.1003 28.7008
RKO GDSC1; GDSC2 1.1186 6.6427 -0.4043 29.7659
SK-CO-1 GDSC1; GDSC2 1.2928 3.7587 0.9745 22.063
COLO205 GDSC1; GDSC2 1.3403 3.7791 1.0192 21.6047
SNU-175 GDSC2 1.5896 5.3046 0.6747 22.4586
HT115 GDSC1; GDSC2 1.6744 3.6428 1.4271 17.8583
CCK-81 GDSC1; GDSC2 1.7719 5.481 0.7812 21.1293
LS513 GDSC1; GDSC2 1.9036 3.868 1.5969 15.9024
NCI-H716 GDSC1; GDSC2 1.92 5.4441 0.9468 19.6045
NCI-H508 GDSC1; GDSC2 2.0305 4.0236 1.6739 14.923
MDST8 GDSC1; GDSC2 2.0379 3.3459 1.9141 13.5389
GP5d GDSC1; GDSC2 2.1742 6.0299 0.9233 18.7744
CL-11 GDSC1; GDSC2 2.2453 4.2122 1.8241 13.1632
NCI-H747 GDSC1; GDSC2 2.2776 7.4093 0.3538 21.5578
DiFi GDSC1; GDSC2 2.3333 6.6819 0.7606 19.1279
SW948 GDSC1; GDSC2 2.3906 3.4607 2.2646 10.0191
KM12 GDSC1; GDSC2 2.4157 4.979 1.6548 13.5188
LS123 GDSC1; GDSC2 2.4164 4.8054 1.7361 13.0233
SNU-C2B GDSC1; GDSC2 2.6111 4.128 2.239 9.2486
HCC2998 GDSC1; GDSC2 2.6739 4.4041 2.1775 9.3796
RCM-1 [Human ESC] GDSC1; GDSC2 2.6801 4.411 2.1805 9.3384
HT-29 GDSC1; GDSC2 2.694 4.477 2.1636 9.3896
CaR-1 GDSC1; GDSC2 2.8116 6.427 1.3259 14.1514
SW626 GDSC1; GDSC2 2.8831 5.133 2.029 9.5571
HCT 15 GDSC1; GDSC2 2.9229 4.5168 2.3663 7.3198
SNU-407 GDSC1; GDSC2 2.9646 6.5717 1.3904 13.262
SNU-C5 GDSC1; GDSC2 3.3465 5.4276 2.2895 6.4652
HT-55 GDSC1; GDSC2 3.4245 4.9463 2.5935 4.3223
SW1417 GDSC1; GDSC2 3.4266 6.0801 2.029 7.8839
SNU-61 GDSC1; GDSC2 3.4456 7.5427 1.3136 12.277
LS411N GDSC1; GDSC2 3.476 5.1804 2.5177 4.6613
LS180 GDSC1; GDSC2 3.6226 8.412 1.0229 13.5094
SW1116 GDSC1; GDSC2 3.6259 5.492 2.4786 4.5182
COLO 678 GDSC1; GDSC2 3.6885 6.4249 2.0644 6.9551
LS1034 GDSC1; GDSC2 3.822 6.6129 2.0723 6.568
COLO 320HSR GDSC1; GDSC2 3.9063 5.6987 2.5782 3.256
SNU-81 GDSC1; GDSC2 3.9754 15.0071 -1.9854 26.0124
SNU-283 GDSC2 4.17 8.0101 1.6416 8.3763
SW1463 GDSC1; GDSC2 4.288 10.5673 0.4695 14.8198
LoVo GDSC1; GDSC2 4.319 8.6017 1.4599 9.1171
SW837 GDSC1; GDSC2 4.3644 8.9397 1.3273 9.4734
SW620 GDSC1; GDSC2 4.5716 8.5382 1.6674 7.0683
T84 GDSC1; GDSC2 4.7703 6.9843 2.5104 2.1548
CW-2 GDSC1; GDSC2 5.265 8.0402 2.3177 2.4643
SNU-C1 GDSC1; GDSC2 5.3118 11.5112 0.7435 10.9601
C2BBe1 GDSC1; GDSC2 5.8101 7.8625 2.6425 0.6095
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 2.3924 3.7095 2.1805 10.4848
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-1 GDSC1; GDSC2 2.3666 4.3299 1.8995 12.2328
JHH-4 GDSC1; GDSC2 2.4235 3.3465 2.3347 9.4849
HLE GDSC1; GDSC2 2.6512 7.4954 0.6529 18.0338
SNU-387 GDSC1; GDSC2 2.6802 3.6544 2.5093 7.3796
JHH-1 GDSC1; GDSC2 2.6863 4.0875 2.3337 8.3893
Hep 3B2.1-7 GDSC1; GDSC2 2.9112 5.1481 2.0474 9.3478
SNU-398 GDSC1; GDSC2 2.9866 6.5392 1.426 12.9737
SNU-423 GDSC1; GDSC2 3.009 4.6656 2.3743 6.9759
JHH-6 GDSC1; GDSC2 3.0507 6.8467 1.3287 12.9174
JHH-2 GDSC1; GDSC2 3.1705 4.7577 2.4743 5.8238
Hep-G2/C3A GDSC1; GDSC2 3.2109 4.8533 2.4619 5.7771
SK-HEP-1 GDSC1; GDSC2 3.916 8.3728 1.2729 11.2346
SNU-449 GDSC1; GDSC2 3.9217 5.8246 2.5283 3.5255
JHH-7 GDSC1; GDSC2 4.0977 7.1005 2.0336 6.1534
Huh-7 GDSC1; GDSC2 4.8387 8.4575 1.8813 5.5235
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 186 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1963 GDSC2 -0.6762 1.8494 -0.745 40.4077
NCI-H2171 GDSC2 -0.5271 0.4294 -0.5272 38.6257
LK-2 GDSC1; GDSC2 -0.08 1.069 -0.0815 34.1461
NCI-H524 GDSC1; GDSC2 -0.0756 1.145 -0.0781 34.1073
COR-L311 GDSC2 -0.0099 3.8622 -0.4749 35.5166
Lu-135 GDSC1; GDSC2 0.2135 2.1527 0.1628 31.4477
IST-SL1 GDSC1; GDSC2 0.2536 2.1953 0.2003 31.0587
UMC-11 GDSC1; GDSC2 0.5859 2.5163 0.5111 26.8756
HCC44 GDSC1 0.837 2.1999 0.2594 6.4594
ABC-1 GDSC1; GDSC2 0.9204 3.5793 0.6265 25.6406
HCC33 GDSC2 0.9844 3.4871 0.7239 24.8248
NCI-H460 GDSC1; GDSC2 1.0177 4.7384 0.3166 26.8191
NCI-H1048 GDSC1; GDSC2 1.0217 3.6815 0.705 24.7543
NCI-H292 GDSC1; GDSC2 1.0284 3.7639 0.6857 24.8271
LC-2/ad GDSC1; GDSC2 1.0562 2.9709 0.9355 22.5546
NCI-H847 GDSC1; GDSC2 1.0949 2.9195 0.9884 22.899
NCI-H209 GDSC1; GDSC2 1.0964 4.5116 0.4894 25.5675
SBC-1 GDSC1; GDSC2 1.1026 3.6195 0.8126 23.8046
NCI-H748 GDSC2 1.1559 6.6113 -0.3525 29.3824
NCI-H720 GDSC1; GDSC2 1.1993 4.6555 0.542 24.8335
NCI-H2081 GDSC1; GDSC2 1.28 3.1278 1.1434 21.2037
NCI-H2170 GDSC1; GDSC2 1.3335 3.0009 1.2304 19.78
NCI-H1436 GDSC1; GDSC2 1.3507 3.6643 1.0683 21.2882
NCI-H1876 GDSC1; GDSC2 1.3527 3.6783 1.066 21.2914
NCI-H2227 GDSC1; GDSC2 1.4002 4.3172 0.8885 22.0673
NCI-H446 GDSC1; GDSC2 1.4003 4.0728 0.9807 21.5536
DMS 273 GDSC1; GDSC2 1.4391 3.5695 1.1946 20.1963
HCC15 GDSC1; GDSC2 1.4639 2.9884 1.3745 19.1085
VMRC-LCD GDSC1; GDSC2 1.49 2.9212 1.4161 18.7652
LXF 289 GDSC1; GDSC2 1.4984 3.7204 1.2103 19.8441
NCI-H1781 GDSC1; GDSC2 1.5412 3.961 1.173 19.8646
LB647-SCLC GDSC1; GDSC2 1.5551 4.2286 1.0878 20.2845
CPC-N GDSC1; GDSC2 1.5641 4.196 1.11 20.1199
NCI-H2085 GDSC1; GDSC2 1.5669 3.3733 1.3923 17.8931
Calu-6 GDSC1; GDSC2 1.6129 4.8056 0.9147 21.0206
NCI-H810 GDSC1; GDSC2 1.6136 3.7143 1.3374 18.6273
NCI-H211 GDSC1 1.6914 4.4915 0.4886 11.6176
NCI-H841 GDSC1 1.7001 3.6536 0.9117 9.7325
A-427 GDSC1; GDSC2 1.7376 4.2931 1.2566 18.5512
Lu-139 GDSC1; GDSC2 1.7472 5.2748 0.8487 20.8471
NCI-H1437 GDSC1; GDSC2 1.8165 4.3612 1.3126 17.2833
NCI-H647 GDSC1; GDSC2 1.8576 4.2141 1.4151 17.1384
BEN GDSC1; GDSC2 1.8685 4.2608 1.4081 16.5423
NCI-H1155 GDSC1; GDSC2 1.8777 6.0001 0.6477 21.459
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2 1.9063 4.4009 1.3908 17.0777
NCI-H1755 GDSC1; GDSC2 1.9701 4.0227 1.6099 15.545
Lu-134-A GDSC1; GDSC2 1.9794 4.8189 1.2878 17.3851
NCI-H1105 GDSC1; GDSC2 2.0076 4.9759 1.247 17.5139
A-549 GDSC1; GDSC2 2.1058 4.788 1.4307 16.0444
LCLC-97TM1 GDSC1; GDSC2 2.114 6.3645 0.7055 20.2389
NCI-H2122 GDSC1; GDSC2 2.1763 5.8232 1.0234 17.571
SBC-3 GDSC1; GDSC2 2.1946 6.2043 0.8595 19.0666
COR-L279 GDSC1; GDSC2 2.2267 3.9329 1.9181 12.6921
NCI-H1648 GDSC1; GDSC2 2.2376 4.8945 1.5163 14.507
NCI-H1693 GDSC1; GDSC2 2.3393 4.0725 1.9808 11.4522
NCI-H2731 GDSC1; GDSC2 2.3616 4.1145 1.9865 11.7381
SW1271 GDSC1; GDSC2 2.4113 4.0358 2.0714 11.0378
PC-14 GDSC1; GDSC2 2.4276 4.1173 2.0542 10.6907
NCI-H2228 GDSC1; GDSC2 2.4572 3.9673 2.1479 10.0429
RERF-LC-KJ GDSC1; GDSC2 2.4602 5.2103 1.5898 13.7506
EPLC-272H GDSC1; GDSC2 2.4951 5.6057 1.4345 14.5708
NCI-H1792 GDSC1; GDSC2 2.5263 3.2988 2.4598 8.3336
COR-L303 GDSC2 2.5338 4.3809 2.0476 10.6964
NCI-H2023 GDSC1; GDSC2 2.5657 4.3727 2.0835 9.9998
NCI-H82 GDSC1; GDSC2 2.5663 3.4364 2.4634 8.1325
NCI-H69 GDSC1; GDSC2 2.5667 4.9641 1.8098 12.0199
NCI-H520 GDSC1; GDSC2 2.5729 5.0942 1.7541 12.3387
RERF-LC-MS GDSC1; GDSC2 2.5893 3.6732 2.405 8.3624
HCC78 GDSC1; GDSC2 2.5945 5.2661 1.6927 12.6388
LC-1/sq GDSC1; GDSC2 2.6104 5.6744 1.5104 13.7025
RERF-LC-Sq1 GDSC1; GDSC2 2.6487 5.3831 1.6878 12.4784
COR-L321 GDSC1; GDSC2 2.749 4.8535 2.0385 9.9607
NCI-H1770 GDSC1; GDSC2 2.7555 4.6119 2.1603 9.1861
LCLC-103H GDSC1; GDSC2 2.7998 15.9363 -3.4255 32.4556
NCI-H1703 GDSC1; GDSC2 2.8038 5.1524 1.9457 10.3454
NCI-H3255 GDSC1; GDSC2 2.8548 5.7079 1.7204 11.5767
NCI-H2009 GDSC1; GDSC2 2.914 6.9885 1.1385 14.9507
NCI-H740 GDSC2 2.9374 4.4859 2.395 7.0915
SK-MES-1 GDSC1; GDSC2 2.9658 5.7613 1.7941 10.7546
DMS 114 GDSC1; GDSC2 2.9709 3.7876 2.757 4.7479
NCI-H1734 GDSC2 2.9835 4.3635 2.4978 6.2928
HCC827 GDSC1; GDSC2 2.9927 6.0511 1.6741 11.4174
NCI-H322M GDSC1; GDSC2 3.0021 6.2881 1.5645 12.0693
NCI-H64 GDSC1; GDSC2 3.0147 5.6277 1.9039 9.9097
NCI-H358 GDSC1; GDSC2 3.0498 6.4434 1.529 11.7253
EMC-BAC-1 GDSC1; GDSC2 3.0557 7.7301 0.8923 15.9527
NCI-H838 GDSC1; GDSC2 3.0626 6.6058 1.4591 12.5312
HCC366 GDSC1; GDSC2 3.0651 4.202 2.6531 5.0458
NCI-H2810 GDSC1; GDSC2 3.1077 4.9234 2.3363 6.6544
NCI-H596 GDSC1; GDSC2 3.1332 4.261 2.6871 4.6038
NCI-H1568 GDSC1; GDSC2 3.1341 6.6941 1.4769 12.2009
NCI-H1623 GDSC1; GDSC2 3.1512 6.3261 1.6752 10.9168
NCI-H1688 GDSC1; GDSC2 3.1709 4.5499 2.578 5.1683
NCI-H187 GDSC1 3.1714 4.564 1.5126 1.1588
NCI-H2110 GDSC1; GDSC2 3.1764 6.4711 1.6245 11.1561
NCI-H1944 GDSC1; GDSC2 3.1862 5.3419 2.1967 7.5285
NCI-H1304 GDSC1 3.2048 4.9183 1.3804 1.8848
NCI-H290 GDSC1; GDSC2 3.2058 8.1257 0.8226 15.8904
Ms-1 GDSC1; GDSC2 3.2097 5.7119 2.0321 8.4965
NCI-H661 GDSC1; GDSC2 3.2137 7.8135 0.9853 14.4358
NCI-H2196 GDSC2 3.2257 6.5311 1.6365 10.9327
NCI-H526 GDSC1; GDSC2 3.2397 7.1778 1.3251 12.8116
IST-SL2 GDSC1; GDSC2 3.2511 7.9824 0.9324 15.119
NCI-H1838 GDSC1; GDSC2 3.2957 5.372 2.275 6.4732
NCI-H2030 GDSC1; GDSC2 3.2978 8.2443 0.8406 15.011
NCI-H3122 GDSC1; GDSC2 3.3125 6.1786 1.8857 8.8007
NCI-H250 GDSC2 3.3238 8.7615 0.6037 16.7663
NCI-H1694 GDSC1; GDSC2 3.3353 7.5619 1.2131 13.2059
NCI-H2795 GDSC1; GDSC2 3.347 5.8392 2.0842 7.7626
ChaGo-K-1 GDSC1; GDSC2 3.409 8.2081 0.951 14.5417
CAL-12T GDSC1; GDSC2 3.4619 5.9146 2.1403 7.0826
NCI-H2172 GDSC1; GDSC2 3.4801 5.0199 2.6009 4.1253
NCI-H1869 GDSC1 3.4902 6.2636 0.9448 4.2168
NCI-H146 GDSC1; GDSC2 3.5231 8.4817 0.9077 14.4619
HOP-62 GDSC1; GDSC2 3.5291 5.1172 2.5905 4.0625
Lu-65 GDSC1; GDSC2 3.5298 6.1205 2.0919 7.202
SHP-77 GDSC1; GDSC2 3.5301 12.0352 -0.8624 23.1857
Lu-165 GDSC1; GDSC2 3.5647 4.7744 2.7868 2.7446
NCI-H2066 GDSC1; GDSC2 3.5965 5.2293 2.5863 3.9176
NCI-H510A GDSC1; GDSC2 3.6884 8.6148 0.9744 13.6083
NCI-H2804 GDSC1; GDSC2 3.7187 10.7978 -0.0907 18.6715
NCI-H1563 GDSC1; GDSC2 3.7511 5.1903 2.7167 2.7495
HOP-92 GDSC1; GDSC2 3.7775 9.5589 0.5745 15.1376
NCI-H345 GDSC1; GDSC2 3.7892 6.1947 2.2539 5.5183
NCI-H2291 GDSC1; GDSC2 3.7912 7.0453 1.8354 8.1194
Lu-99A GDSC1; GDSC2 3.8027 8.684 1.0303 12.5495
NCI-H2373 GDSC1; GDSC2 3.8163 6.4057 2.1701 5.9736
NCI-H2135 GDSC1; GDSC2 3.8851 5.6153 2.6039 3.1461
COR-L88 GDSC1; GDSC2 3.9098 6.5673 2.1593 5.8164
COR-L32 GDSC2 3.9453 7.3942 1.7791 8.0807
DMS 79 GDSC1; GDSC2 3.9601 6.0244 2.4584 3.8667
NCI-H2347 GDSC1; GDSC2 3.9668 6.4246 2.2696 5.0044
EBC-1 GDSC1; GDSC2 4.0769 6.9308 2.1014 5.786
SBC-5 GDSC1; GDSC2 4.0781 7.7528 1.7008 8.2364
LOU-NH91 GDSC1; GDSC2 4.0831 7.3596 1.8969 7.0244
NCI-H1573 GDSC1; GDSC2 4.1117 6.7201 2.2275 4.7699
NCI-H2803 GDSC2 4.1524 7.0187 2.1116 5.5557
NCI-H2141 GDSC1; GDSC2 4.1608 5.8807 2.6556 2.3131
COR-L95 GDSC1; GDSC2 4.1614 5.8679 2.6618 2.2772
PaCa-3 GDSC1; GDSC2 4.2341 6.3065 2.504 3.0495
NCI-H1993 GDSC1; GDSC2 4.2872 7.7761 1.839 6.9102
NCI-H196 GDSC1; GDSC2 4.3036 6.2726 2.5622 2.5048
NCI-H2869 GDSC1; GDSC2 4.3118 7.1217 2.1702 4.8642
NCI-H2369 GDSC1; GDSC2 4.3393 6.5607 2.4514 3.161
NCI-H2461 GDSC1; GDSC2 4.3395 8.0097 1.7624 7.2557
NCI-H1651 GDSC1; GDSC2 4.3587 9.7294 0.9358 12.0772
NCI-H1975 GDSC1; GDSC2 4.3626 8.5857 1.4988 8.7832
NCI-H1581 GDSC1; GDSC2 4.383 10.5192 0.5648 13.6437
NCI-H2722 GDSC1; GDSC2 4.4194 8.0783 1.7846 6.946
NCI-H1915 GDSC1; GDSC2 4.42 7.9103 1.8658 6.2379
NCI-H2405 GDSC1; GDSC2 4.4523 6.7595 2.4288 3.0902
COR-L23 GDSC1; GDSC2 4.4894 9.7896 1.0019 11.3845
NCI-H522 GDSC1; GDSC2 4.5024 8.8453 1.4714 8.3396
EKVX GDSC1; GDSC2 4.5181 9.705 1.064 10.9622
NCI-H2342 GDSC1; GDSC2 4.5416 7.1916 2.2844 3.7537
NCI-H1836 GDSC1; GDSC2 4.5767 6.5461 2.5964 1.9828
NCI-H2029 GDSC1; GDSC2 4.6091 6.9629 2.4293 2.8261
IA-LM GDSC1; GDSC2 4.6453 8.6238 1.6762 7.1066
NCI-H2444 GDSC1; GDSC2 4.6523 8.3269 1.8224 6.2316
NCI-H835 GDSC1; GDSC2 4.6529 8.391 1.7923 6.4074
NCI-H1793 GDSC1; GDSC2 4.6869 6.5341 2.6602 1.4656
NCI-H727 GDSC1; GDSC2 4.6879 8.7702 1.6349 7.2601
NCI-H1092 GDSC1; GDSC2 4.7214 8.5027 1.7844 6.3151
NCI-H1299 GDSC1; GDSC2 4.748 9.5074 1.3218 8.663
NCI-H2595 GDSC1; GDSC2 4.7694 9.656 1.265 9.2369
SK-LU-1 GDSC1 4.7934 18.7036 -4.1535 26.0858
NCI-H1435 GDSC1; GDSC2 4.8355 6.6932 2.6681 1.3098
SW1573 GDSC1; GDSC2 4.9841 9.2476 1.6034 6.8426
Calu-3 GDSC1; GDSC2 5.0245 8.5125 1.9709 4.6774
NCI-H1650 GDSC1; GDSC2 5.0337 8.4728 1.9947 4.374
NCI-H23 GDSC1; GDSC2 5.0539 10.7011 0.9569 10.3537
NCI-H226 GDSC1; GDSC2 5.0666 11.3731 0.6413 12.0378
COLO 668 GDSC1; GDSC2 5.1053 9.192 1.7066 6.0228
NCI-H650 GDSC1; GDSC2 5.1626 7.3029 2.5758 1.3758
EMC-BAC-2 GDSC1; GDSC2 5.1789 11.1444 0.8291 10.7831
NCI-H2818 GDSC1; GDSC2 5.1917 9.9413 1.4106 7.5322
COR-L105 GDSC1; GDSC2 5.3687 14.4061 -0.6207 17.4371
KNS-62 GDSC1; GDSC2 5.3885 10.8105 1.1281 8.7175
NCI-H1666 GDSC1; GDSC2 5.5155 11.7211 0.7797 10.0297
NCI-H1355 GDSC1; GDSC2 5.5411 8.5973 2.2234 2.487
NCI-H513 GDSC1; GDSC2 5.6643 7.6149 2.6754 0.6149
NCI-H1341 GDSC1; GDSC2 5.7466 10.205 1.6295 5.3397
NCI-H441 GDSC1; GDSC2 5.8646 7.736 2.7103 0.4212
DMS 53 GDSC1; GDSC2 5.8768 7.9332 2.6431 0.5936
NCI-H2591 GDSC1; GDSC2 5.8921 13.9536 -0.0345 13.2818
NCI-H2087 GDSC1; GDSC2 6.5373 17.6285 -1.3613 17.9146
⏷ Show the Full List of 186 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 2.8212 4.8453 2.1112 9.2568
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-11 GDSC1; GDSC2 0.1166 3.5691 -0.2466 33.8812
KYSE-510 GDSC1; GDSC2 1.3238 3.9142 0.955 22.0326
KYSE-150 GDSC1; GDSC2 1.5036 5.3728 0.5566 23.4575
OE19 GDSC1; GDSC2 2.08 3.4283 1.9361 13.2269
EC-GI-10 GDSC1; GDSC2 2.5746 6.2587 1.1922 15.7579
KYSE-410 GDSC1; GDSC2 2.5839 4.9025 1.8557 11.6765
OE33 GDSC1; GDSC2 2.6055 3.5876 2.4543 8.0121
OE21 GDSC1; GDSC2 2.7722 9.2773 -0.1254 22.2691
KYSE-520 GDSC1; GDSC2 2.8439 4.048 2.5109 6.7179
KYSE-140 GDSC1; GDSC2 2.8635 5.537 1.8125 10.9739
TE-1 GDSC1; GDSC2 3.2162 6.3736 1.7071 10.5205
KYSE-450 GDSC1; GDSC2 3.249 8.7738 0.535 17.3694
KYSE-70 GDSC1; GDSC2 3.33 4.9437 2.5178 5.068
T.T GDSC1; GDSC2 3.4243 8.3555 0.8899 14.851
KYSE-180 GDSC1; GDSC2 3.4571 6.1765 2.0057 7.9455
TE-10 GDSC1; GDSC2 3.4605 6.4672 1.8632 8.8321
TE-4 GDSC1; GDSC2 3.4607 6.3069 1.9434 8.3276
KYSE-270 GDSC1; GDSC2 3.5194 6.7251 1.782 8.8629
TE-5 GDSC1; GDSC2 3.861 7.286 1.7692 8.3522
TE-8 GDSC1; GDSC2 3.918 8.0947 1.4123 10.3914
TE-15 GDSC1; GDSC2 4.0201 8.2376 1.4189 10.0908
TE-9 GDSC1; GDSC2 4.2165 7.3887 1.9772 6.2303
COLO 680N GDSC1; GDSC2 4.9477 9.8016 1.3164 8.5603
TE-6 GDSC1; GDSC2 5.872 8.1638 2.5547 0.8706
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Caov-3 GDSC2 -0.2533 1.9964 -0.3139 36.1663
TOV-21G GDSC1; GDSC2 0.6745 3.6139 0.3479 28.2491
OVK18 GDSC1; GDSC2 1.1293 6.9596 -0.5391 30.2829
OVISE GDSC1; GDSC2 1.9908 7.7201 -0.0656 24.7222
EFO-21 GDSC1; GDSC2 1.9918 5.8914 0.8109 20.104
TYK-nu GDSC1; GDSC2 2.1157 5.8399 0.9565 18.8
JHOS-2 GDSC1; GDSC2 2.1234 6.3465 0.7232 20.1049
OC 314 GDSC1; GDSC2 2.4268 6.2842 1.0417 17.1689
OAW42 GDSC1 2.5038 5.247 0.7748 7.9669
DOV13 GDSC1; GDSC2 2.5152 5.2604 1.6192 13.3727
OVTOKO GDSC1; GDSC2 2.7906 6.3069 1.3664 13.9736
ES-2 GDSC1; GDSC2 2.8093 4.6694 2.1846 8.8445
JHOS-4 GDSC1; GDSC2 2.9358 4.4305 2.4202 6.9405
OAW28 GDSC1; GDSC2 3.1119 8.049 0.7811 15.8901
A2780 GDSC1; GDSC2 3.1361 4.5473 2.5482 5.4671
OV56 GDSC1; GDSC2 3.3368 5.1085 2.441 5.5343
Caov-4 GDSC1; GDSC2 3.5046 5.2142 2.5234 4.5493
RMG-I GDSC1; GDSC2 3.5203 6.209 2.0402 7.5535
OVKATE GDSC1; GDSC2 3.596 4.991 2.7033 3.1884
FU-OV-1 GDSC1 3.6054 6.7837 0.7767 5.1273
OVCAR-4 GDSC1; GDSC2 3.65 7.9986 1.251 12.0797
SK-OV-3 GDSC1; GDSC2 3.9636 8.1845 1.4025 10.3332
EFO-27 GDSC1; GDSC2 4.079 8.5292 1.3192 10.5403
Kuramochi GDSC1; GDSC2 4.1499 6.5347 2.3421 4.1685
IGROV-1 GDSC1; GDSC2 4.247 9.2687 1.0799 11.5277
OVCAR-8 GDSC1; GDSC2 4.5003 8.4756 1.6488 7.58
TOV-112D GDSC1; GDSC2 5.0895 17.2483 -2.2286 24.0341
OVCAR-5 GDSC1; GDSC2 5.1281 10.747 0.9854 10.0376
OVCAR-3 GDSC1; GDSC2 5.2769 10.3724 1.2625 8.1945
OV-90 GDSC1; GDSC2 6.3452 14.4308 0.0398 12.3921
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HPAC GDSC1; GDSC2 0.9018 3.0718 0.7447 25.1011
MIA PaCa-2 GDSC1; GDSC2 1.395 4.1431 0.949 21.0055
HuP-T4 GDSC1; GDSC2 2.161 5.3529 1.229 17.0301
HPAF-II GDSC1 2.4002 7.1346 -0.9934 10.9745
BxPC-3 GDSC1; GDSC2 2.5619 4.9749 1.8001 12.0969
KP-4 GDSC1; GDSC2 2.5974 7.8874 0.4104 19.5113
DAN-G GDSC1; GDSC2 2.7183 3.5489 2.5897 6.7576
PSN1 GDSC1; GDSC2 3.1848 9.7869 -0.0256 20.4727
Capan-2 GDSC1; GDSC2 3.1854 4.7826 2.4749 5.7736
Hs 766T GDSC1; GDSC2 3.2698 5.0871 2.3955 6.0189
SUIT-2 GDSC1; GDSC2 3.2832 4.4086 2.746 3.6302
Panc 02.03 GDSC1; GDSC2 3.3398 6.1085 1.9435 8.671
Panc 04.03 GDSC1; GDSC2 3.3922 5.1447 2.4684 5.2031
Panc 10.05 GDSC1; GDSC2 3.4052 7.0291 1.5372 10.6484
CFPAC-1 GDSC1; GDSC2 3.4338 6.706 1.7222 9.7911
Capan-1 GDSC1; GDSC2 3.4656 4.6134 2.7917 2.8593
KP-1N GDSC1; GDSC2 3.8079 6.1328 2.298 5.1989
SU.86.86 GDSC1; GDSC2 3.8498 6.823 1.9895 6.7735
Panc 03.27 GDSC1; GDSC2 3.8576 6.1105 2.3449 4.6255
QGP-1 GDSC1; GDSC2 4.0728 6.7416 2.1902 5.2526
PaTu 8902 GDSC1; GDSC2 4.2791 6.3061 2.532 2.8078
KP-2 GDSC1; GDSC2 4.3698 7.2043 2.1692 4.7527
HuP-T3 GDSC1; GDSC2 4.7876 11.3867 0.4362 13.3577
AsPC-1 GDSC1; GDSC2 4.8656 8.3267 1.9591 4.8556
PaTu 8988t GDSC1; GDSC2 4.8672 6.3169 2.8336 0.5867
YAPC GDSC1; GDSC2 4.9581 8.5272 1.9235 5.062
Panc 08.13 GDSC1; GDSC2 4.968 11.6215 0.4511 12.8735
SW1990 GDSC1; GDSC2 5.4443 8.9063 2.0372 3.5224
MZ-PC-1 GDSC1; GDSC2 5.5669 8.8224 2.1404 2.95
KP-3 GDSC1; GDSC2 5.7367 9.5068 1.9345 3.7578
PL4 GDSC1; GDSC2 6.4276 8.3547 2.7014 0.2515
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-Mes1 GDSC1; GDSC2 2.556 6.1101 1.2474 15.4906
MSTO-211H GDSC1; GDSC2 2.5741 6.6489 1.0005 16.8985
NCI-H2452 GDSC1; GDSC2 3.3839 5.9978 2.0353 7.9655
NCI-H2052 GDSC1; GDSC2 3.4595 4.906 2.6414 3.9251
NCI-H28 GDSC1; GDSC2 3.6882 7.2668 1.6458 9.5657
MPP 89 GDSC1; GDSC2 4.0883 7.5319 1.8164 7.5049
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1; GDSC2 3.1654 5.4806 2.1095 8.1429
DU145 GDSC1; GDSC2 4.2932 8.2822 1.5973 8.0732
22Rv1 GDSC1; GDSC2 4.4204 6.8638 2.3613 3.532
VCaP GDSC1; GDSC2 4.9361 7.9109 2.1922 3.5988
NCI-H660 GDSC2 5.3086 6.8414 2.8185 0.3945
PC-3 GDSC1; GDSC2 7.737 21.0912 -2.2071 18.2352
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; GDSC2 2.7165 5.0887 1.8944 10.9657
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 800 GDSC1; GDSC2 1.4153 6.2442 0.0752 26.3103
COLO 792 GDSC1; GDSC2 1.6356 4.125 1.2135 18.5662
G-mel GDSC1; GDSC2 1.7168 3.1548 1.6128 16.6501
CHL-1 GDSC1; GDSC2 1.7733 6.0176 0.5364 22.4772
HMV-II GDSC1; GDSC2 1.8857 3.9692 1.5401 15.7393
WM35 GDSC1; GDSC2 1.8906 4.1174 1.4884 16.5785
A101D GDSC1; GDSC2 1.9648 5.5549 0.9407 19.4655
WM793 GDSC1; GDSC2 1.967 4.6377 1.3539 17.0468
A-431 GDSC1; GDSC2 1.9684 3.948 1.6365 15.3999
RPMI-7951 GDSC1; GDSC2 2.0359 3.7604 1.7782 14.304
A-388 GDSC1; GDSC2 2.0395 4.1443 1.6356 15.107
WM1552C GDSC1; GDSC2 2.1016 3.7078 1.8679 13.5121
IPC-298 GDSC1; GDSC2 2.216 3.2395 2.1364 11.5146
SK-MEL-24 GDSC1; GDSC2 2.2424 2.9819 2.2162 10.5881
SK-MEL-30 GDSC1; GDSC2 2.2937 3.4166 2.1726 10.5826
Hs 938.T GDSC1; GDSC2 2.3664 3.2051 2.3086 9.89
Mel Ho GDSC1; GDSC2 2.3871 3.4153 2.2747 9.9789
G-361 GDSC1; GDSC2 2.4312 3.6079 2.259 9.8715
UACC-62 GDSC1; GDSC2 2.457 4.18 2.0578 10.9349
A-375 GDSC1; GDSC2 2.4655 5.7489 1.3373 14.7443
IST-MEL1 GDSC1; GDSC2 2.5716 7.211 0.7214 18.5167
M14 GDSC1 2.6092 6.4035 0.2831 11.3413
MZ-MEL-7 GDSC1; GDSC2 2.6206 3.4514 2.5176 7.5898
Mel JuSo GDSC1; GDSC2 2.6543 4.039 2.3224 8.5818
DJM-1 GDSC1; GDSC2 2.7231 6.2332 1.3414 14.3507
SK-MEL-3 GDSC1; GDSC2 2.7278 3.6923 2.545 6.9741
SK-MEL-2 GDSC1 2.7754 6.3892 0.4133 9.871
LOX-IMVI GDSC1; GDSC2 2.7798 5.5579 1.7253 11.7966
MZ-MEL-2 GDSC1; GDSC2 2.7883 6.147 1.4433 13.5109
HT-144 GDSC1; GDSC2 2.8028 5.9604 1.5485 12.815
Hs 940.T GDSC1; GDSC2 2.8312 4.1914 2.4321 7.2441
SK-MEL-1 GDSC1; GDSC2 2.8505 6.378 1.3852 13.6618
IGR-1 GDSC1; GDSC2 2.8561 3.4703 2.7666 5.1596
SK-MEL-31 GDSC1; GDSC2 2.9407 3.8159 2.7138 5.1244
CP50-MEL-B GDSC1; GDSC2 2.9502 4.7874 2.2602 7.887
VMRC-MELG GDSC2 3.0973 6.9476 1.3187 13.2846
SK-MEL-5 GDSC1; GDSC2 3.0998 5.5465 2.0195 8.9141
SK-MEL-28 GDSC1; GDSC2 3.1435 4.6797 2.4892 5.6142
LB2518-MEL GDSC1; GDSC2 3.2364 4.3895 2.7153 4.097
WM278 GDSC1; GDSC2 3.2376 5.1625 2.3305 6.3012
GAK GDSC1; GDSC2 3.2469 4.0325 2.9023 2.8833
COLO 783 GDSC1; GDSC2 3.4406 4.6636 2.7473 3.3076
LB373-MEL-D GDSC1; GDSC2 3.7592 5.9941 2.3304 5.115
UACC-257 GDSC1; GDSC2 3.7728 6.156 2.2608 5.5152
WM115 GDSC1; GDSC2 3.7801 5.3143 2.6769 2.9287
COLO 679 GDSC1; GDSC2 3.8934 6.9032 1.9824 6.9516
IGR-37 GDSC1; GDSC2 4.0635 7.0829 2.0179 6.1104
SH-4 GDSC1; GDSC2 4.0774 7.0882 2.0253 6.251
MeWo GDSC1; GDSC2 4.0856 5.6613 2.7108 2.0581
CP66-MEL GDSC1; GDSC2 4.2451 7.9887 1.706 7.8104
MMAc-SF GDSC1; GDSC2 4.2489 7.6199 1.8879 6.4706
A2058 GDSC1; GDSC2 4.516 6.8888 2.408 2.991
WT2-iPS GDSC1; GDSC2 4.6572 7.8629 2.0444 4.9243
COLO 829 GDSC1; GDSC2 4.8001 11.2148 0.5293 12.8492
451Lu GDSC1; GDSC2 5.6218 8.3135 2.3825 1.7497
RVH-421 GDSC1; GDSC2 5.6564 10.7594 1.3219 7.1519
EquiPSC Line K2 GDSC1; GDSC2 3.2963 5.1113 2.4058 5.8756
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 -0.406 4.2288 -1.0258 39.675
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EW-8 GDSC1; GDSC2 0.4742 1.9211 0.457 28.6643
TE 441.T GDSC2 1.4986 5.3699 0.5528 23.4993
Hs 633.T GDSC1; GDSC2 1.6462 3.6254 1.4021 17.4961
G-402 GDSC1; GDSC2 1.8395 4.3417 1.3447 17.62
SW982 GDSC1; GDSC2 1.9033 3.7318 1.6451 15.6314
SK-LMS-1 GDSC1; GDSC2 2.2777 3.7251 2.0514 11.7113
STS-0421 GDSC1; GDSC2 2.2818 3.7171 2.0587 11.6521
GCT GDSC1; GDSC2 2.6178 5.0851 1.8018 11.4753
RKN GDSC1; GDSC2 3 8.6932 0.3635 19.067
SW684 GDSC1; GDSC2 3.1758 3.951 2.8786 3.2626
MES-SA GDSC1; GDSC2 3.1821 8.7494 0.4908 17.8147
Rh18 GDSC1; GDSC2 3.3321 4.8068 2.5879 4.6178
G-401 GDSC1; GDSC2 3.4249 6.4325 1.8516 9.0051
RD GDSC1; GDSC2 3.735 6.0828 2.2688 5.3662
HT-1080 GDSC1; GDSC2 3.8258 6.9042 1.9314 7.4351
Rh41 GDSC1; GDSC2 4.0008 8.855 1.0988 11.6517
SW872 GDSC1; GDSC2 4.0022 6.6397 2.1901 5.225
Rh30 GDSC1; GDSC2 4.0398 6.4249 2.3203 4.5331
A-204 GDSC1; GDSC2 4.7247 11.9707 0.1036 15.168
SK-UT-1 GDSC1; GDSC2 4.9824 9.5643 1.4525 7.4561
VA-ES-BJ GDSC1; GDSC2 5.0447 8.5522 1.9649 4.676
MFH-ino GDSC1; GDSC2 5.1959 7.5294 2.4986 1.6844
KYM-1 GDSC1; GDSC2 5.5874 6.8572 2.9157 0.11
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-39 GDSC1; GDSC2 0.5527 1.5961 0.5499 27.8034
HGC-27 GDSC1; GDSC2 0.5915 2.0353 0.5712 27.5027
ECC10 GDSC1; GDSC2 0.795 2.9044 0.666 26.0229
SK-GT-2 GDSC1; GDSC2 1.4729 4.0129 1.0807 20.6788
MKN1 GDSC1 1.7918 6.6987 -1.2194 14.2975
RERF-GC-1B GDSC1; GDSC2 1.8054 3.8626 1.4931 16.3296
AGS GDSC1; GDSC2 2.127 4.8498 1.4247 15.9975
SNU-16 GDSC1; GDSC2 2.2552 5.0523 1.4617 15.285
NCI-N87 GDSC1; GDSC2 2.5337 3.7214 2.3272 9.0443
IM95 GDSC1; GDSC2 2.5544 7.058 0.7811 17.6418
GCIY GDSC1; GDSC2 2.8161 4.1177 2.4511 7.185
NUGC-3 GDSC1; GDSC2 2.8173 7.6872 0.7057 17.2126
MKN28 GDSC1; GDSC2 3.1493 4.2272 2.7185 4.2034
SCH GDSC1; GDSC2 3.1726 4.5914 2.5588 5.2842
SNU-1 GDSC1; GDSC2 3.2107 6.3118 1.7333 10.3734
NUGC-4 GDSC1; GDSC2 3.2605 4.2797 2.791 3.5445
OCUM-1 GDSC1; GDSC2 3.2744 8.1096 0.8884 15.304
MKN45 GDSC1; GDSC2 3.6038 6.1256 2.1475 6.4245
MKN7 GDSC1; GDSC2 3.6922 6.6571 1.952 7.6486
ECC12 GDSC2 3.968 6.9173 2.0301 6.4765
Fu97 GDSC1; GDSC2 3.9704 6.8702 2.0549 6.3177
23132/87 GDSC1; GDSC2 3.9889 6.237 2.3758 4.306
KATO III GDSC1; GDSC2 4.052 7.7436 1.6861 8.3893
RF-48 GDSC1; GDSC2 4.1156 9.6679 0.7836 13.5501
TGBC11TKB GDSC1; GDSC2 4.2553 7.5059 1.9475 6.3247
Hs 746.T GDSC1; GDSC2 4.4359 9.4818 1.1138 10.521
SNU-5 GDSC1; GDSC2 4.8647 10.9708 0.6945 12.2096
TMK-1 GDSC1; GDSC2 5.261 7.7204 2.4512 1.8291
SNG-M GDSC1; GDSC2 2.8619 5.7995 1.6816 11.7942
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TT2609-C02 GDSC1; GDSC2 0.3697 3.0435 0.1716 29.5727
CGTH-W-1 GDSC1; GDSC2 1.3042 4.0192 0.8966 22.441
IHH-4 GDSC1; GDSC2 1.4308 3.8222 1.1026 20.7415
BHT-101 GDSC1; GDSC2 1.4523 3.2655 1.2967 19.579
ML-1 [Human leukemia] GDSC1; GDSC2 2.0974 5.3056 1.1876 16.9181
FTC-133 GDSC1; GDSC2 2.2815 6.2206 0.9349 18.3144
8505C GDSC1; GDSC2 2.6183 5.1117 1.7896 11.9588
KMH-2 GDSC1; GDSC2 2.7594 5.4033 1.782 11.5143
B-CPAP GDSC1; GDSC2 2.7852 4.5164 2.2344 8.3251
8305C GDSC1; GDSC2 2.8102 4.6226 2.2079 8.6968
K5 GDSC1; GDSC2 3.2556 6.352 1.7513 9.7788
ASH-3 GDSC1; GDSC2 3.3182 4.8112 2.5742 4.7446
TT GDSC1; GDSC2 3.3875 6.917 1.5788 10.4483
WRO GDSC1; GDSC2 3.4199 8.5575 0.7853 15.4629
CAL-62 GDSC1; GDSC2 3.6504 6.5227 1.9864 7.2829
HTC-C3 GDSC1; GDSC2 3.7688 9.0236 0.8344 13.741
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-06A GDSC1; GDSC2 -0.3954 1.1906 -0.4037 37.344
HO-1-N-1 GDSC1; GDSC2 0.3219 3.1526 0.0926 31.2493
JHU-011 GDSC1; GDSC2 0.76 3.0745 0.5895 26.59
HSC-3 GDSC1; GDSC2 0.8009 3.1892 0.6058 26.3099
Detroit 562 GDSC1; GDSC2 0.835 3.1235 0.6594 25.8671
PCI-38 GDSC1 0.8907 10.3664 -3.1402 34.8099
PCI-04B GDSC1; GDSC2 0.9449 3.611 0.6435 25.4365
CAL-33 GDSC1; GDSC2 1.2109 3.2054 1.0489 22.0319
KOSC-2 GDSC1; GDSC2 1.2395 3.7624 0.9154 22.6256
BICR 22 GDSC1; GDSC2 1.3142 3.9688 0.9254 22.2378
BB30-HNC GDSC1; GDSC2 1.3971 3.8774 1.0471 21.1981
KON GDSC1; GDSC2 1.4132 4.7282 0.7381 22.8449
Ca9-22 GDSC1; GDSC2 1.7004 5.2942 0.7925 21.3522
NCI-H3118 GDSC1; GDSC2 1.7755 4.0757 1.3819 17.6748
CAL-27 GDSC1; GDSC2 1.7971 3.5609 1.587 15.8568
BB49-HNC GDSC1 2.1777 5.0242 0.6333 10.1226
JHU-029 GDSC1; GDSC2 2.178 3.879 1.887 13.0759
SCC-4 GDSC1; GDSC2 2.2338 4.6513 1.6219 14.4074
PCI-15A GDSC1; GDSC2 2.245 3.481 2.0996 11.5836
SCC-15 GDSC1; GDSC2 2.2579 5.798 1.1145 17.3473
SAT [Human HNSCC] GDSC1; GDSC2 2.3338 8.1504 0.0418 22.9517
FaDu GDSC1; GDSC2 2.3362 3.3186 2.2471 10.361
DOK GDSC1; GDSC2 2.5652 8.8011 -0.0713 22.0383
BICR 78 GDSC1; GDSC2 2.6304 6.3308 1.2084 15.4694
BICR 31 GDSC2 2.6624 4.1437 2.2844 8.7773
OSC-20 GDSC1; GDSC2 2.8315 6.956 1.0816 15.0396
BICR 10 GDSC1 2.9482 6.9634 0.2573 10.4972
PE/CA-PJ15 GDSC1; GDSC2 3.0188 4.9625 2.2371 7.804
UPCI-SCC-090 GDSC1; GDSC2 3.1227 5.0852 2.2692 7.268
SAS GDSC1; GDSC2 3.1251 4.1749 2.722 4.4119
JHU-022 GDSC1; GDSC2 3.1483 8.7027 0.4855 17.9483
HO-1-u-1 GDSC1; GDSC2 3.2447 4.9428 2.4462 5.7732
HSC-2 GDSC1; GDSC2 3.3529 5.9241 2.0465 7.9833
OSC-19 GDSC1; GDSC2 4.157 8.4605 1.4111 9.7975
BHY GDSC1; GDSC2 4.389 8.9177 1.3558 9.2541
LB771-HNC GDSC1; GDSC2 4.4854 7.7183 2.0014 5.5142
SCC-25 GDSC1; GDSC2 4.7421 7.6899 2.1774 4.007
HSC-4 GDSC2 5.0027 8.8059 1.822 5.5574
SKN-3 GDSC1; GDSC2 5.1563 9.2256 1.7227 5.8383
PCI-30 GDSC1; GDSC2 5.254 11.3534 0.78 10.8876
SCC-9 GDSC1; GDSC2 5.6579 12.8144 0.3531 12.2525
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
5637 GDSC1; GDSC2 0.9258 3.1983 0.7396 25.0147
CAL-29 GDSC1; GDSC2 1.2196 3.1867 1.063 21.9155
BFTC-905 GDSC1; GDSC2 1.4524 3.5889 1.203 20.0897
RT-112 GDSC1; GDSC2 1.6408 3.2805 1.4984 17.6183
KU-19-19 GDSC1; GDSC2 2.2492 3.4657 2.109 11.5126
SW1710 GDSC1; GDSC2 2.2541 5.3544 1.3202 16.1375
SW780 GDSC1; GDSC2 2.4335 6.4163 0.9838 17.4854
647V GDSC1; GDSC2 2.4849 3.4547 2.369 9.0195
RT-4 GDSC1; GDSC2 3.1019 4.4263 2.5772 5.3966
HT-1197 GDSC1; GDSC2 3.3086 4.5468 2.6983 3.9872
639V GDSC1; GDSC2 3.6316 7.5549 1.4577 10.8769
TCCSUP GDSC1; GDSC2 3.8076 7.222 1.7604 8.5432
J82 GDSC1; GDSC2 4.201 6.0982 2.58 2.5803
HT-1376 GDSC1; GDSC2 4.7114 7.0784 2.4363 2.6288
UM-UC-3 GDSC1; GDSC2 5.8781 7.906 2.6537 0.5436
T24 GDSC1; GDSC2 5.9711 8.0691 2.6308 0.5798
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TC-YIK GDSC1 -0.182 1.4412 -0.2553 27.7404
SW954 GDSC1; GDSC2 0.4334 3.9967 -0.0375 31.3142
NT2-D1 GDSC1; GDSC2 1.1375 3.2741 0.9509 22.1078
BPH-1 GDSC1; GDSC2 1.6215 4.1115 1.2036 18.6785
JAR GDSC1; GDSC2 1.9605 3.9847 1.6142 15.5616
KGN GDSC1; GDSC2 1.9617 4.862 1.2507 17.6728
MS751 GDSC1; GDSC2 2.0162 3.907 1.7033 14.8146
HEY GDSC1; GDSC2 2.031 6.4216 0.5983 21.1455
CAL-39 GDSC1; GDSC2 2.0526 3.7932 1.7844 14.1969
PWR-1E GDSC1; GDSC2 2.3968 4.8693 1.687 13.3943
ACC-OV7 GDSC1; GDSC2 2.4265 6.1972 1.0836 16.9227
JEG-3 GDSC1; GDSC2 2.5428 5.4954 1.533 13.8012
OVCA433 GDSC1; GDSC2 2.6431 5.4116 1.6687 12.6158
PA-1 GDSC1; GDSC2 2.7222 5.4289 1.7347 11.934
HeLa GDSC1; GDSC2 2.7616 4.7672 2.0919 9.5857
Ca Ski GDSC1; GDSC2 2.8048 5.2999 1.8746 10.7841
OV17R GDSC1; GDSC2 2.9426 4.8213 2.2366 8.0603
JHOS-3 GDSC1; GDSC2 3.0507 4.3492 2.5678 5.6267
DoTc2 4510 GDSC1; GDSC2 3.162 4.1727 2.7569 3.9306
C-33 A GDSC1; GDSC2 3.2791 5.783 2.0556 8.1414
SiSo GDSC1; GDSC2 3.495 6.1109 2.0689 7.4418
UWB1.289 GDSC1; GDSC2 3.5491 5.4807 2.4255 5.0484
ME-180 GDSC1; GDSC2 3.5637 7.8673 1.2474 12.3414
SKN GDSC1; GDSC2 3.703 9.0066 0.7906 14.622
DSH1 GDSC1; GDSC2 3.7071 10.0246 0.2859 17.3537
C-4-I GDSC1; GDSC2 3.7351 6.9452 1.842 8.2235
OVCA420 GDSC1; GDSC2 3.8093 5.6713 2.5245 3.796
OVMIU GDSC1; GDSC2 4.0455 8.1 1.5058 9.502
LB831-BLC GDSC1; GDSC2 4.0968 6.9138 2.1236 5.6059
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 4.1566 6.2374 2.4872 3.2939
SiHa GDSC1; GDSC2 4.2367 6.3088 2.5046 3.0414
SW962 GDSC1; GDSC2 4.3243 9.8469 0.8525 12.6327
PEO1 GDSC1; GDSC2 4.3323 9.1112 1.2201 10.5025
NCC-IT GDSC2 4.5971 9.8514 1.0493 10.861
HT-3 GDSC1; GDSC2 4.6128 6.9697 2.4284 2.8253
SW756 GDSC1; GDSC2 4.9688 9.6004 1.4264 7.8878
HEC-1 GDSC1; GDSC2 4.9711 9.4601 1.4944 7.4932
NEC8 GDSC1; GDSC2 5.0934 6.9484 2.6865 0.9802
SKG-IIIa GDSC1; GDSC2 5.2317 8.2363 2.2146 3.0318
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8353).
2 Accurate prediction of the relative potencies of members of a series of kinase inhibitors using molecular docking and MM-GBSA scoring. J Med Chem. 2006 Aug 10;49(16):4805-8.
3 DNA double-strand breaks and Aurora B mislocalization induced by exposure of early mitotic cells to H(2)O(2) appear to increase chromatin bridges and resultant cytokinesis failure. Free Radic Biol Med. 2017 Jul;108:129-145. doi: 10.1016/j.freeradbiomed.2017.03.025. Epub 2017 Mar 24.
4 PLK1 targets NOTCH1 during DNA damage and mitotic progression. J Biol Chem. 2019 Nov 22;294(47):17941-17950. doi: 10.1074/jbc.RA119.009881. Epub 2019 Oct 9.