Details of the Drug

General Information of Drug (ID: DMG82ZA)

Drug Name
Ad35-GRIN/ENV
Synonyms Ad35 vector-delivered gag/rt/int/nef + Ad35 vector-delivered env combination vaccine (HIV infection), International AIDS Vaccine Initiative
Indication
Disease Entry ICD 11 Status REF
Human immunodeficiency virus infection 1C62 Phase 1 [1]
Drug Type
Vaccine
Cross-matching ID
TTD ID
D09ZKB

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Human immunodeficiency virus Envelope glycoprotein gp160 (HIV env) TTEC2T3 ENV_HV1H2 Not Available [2]
Human immunodeficiency virus GAG protein (HIV gag) TTFGZB6 GAG_HV1H2 Not Available [2]
Human immunodeficiency virus Negative factor (HIV nef) TT4NXYM NEF_HV1A2 Not Available [2]
Human immunodeficiency virus Rev protein (HIV rev) TTF7I5O REV_HV1H2 Not Available [2]
Human immunodeficiency virus Reverse transcriptase (HIV RT) TT84ETX POL_HV1B1 Not Available [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 ClinicalTrials.gov (NCT01496989) Safety and Immunogenicity Study of HIV-MAG Vaccine +/- IL-12 and Ad35-GRIN/ENV in HIV-uninfected Volunteers. U.S. National Institutes of Health.
2 A phase I double blind, placebo-controlled, randomized study of a multigenic HIV-1 adenovirus subtype 35 vector vaccine in healthy uninfected adults. PLoS One. 2012;7(8):e41936.