Details of the Drug

General Information of Drug (ID: DMGJTL3)

Drug Name

SMaRT FVIII

Synonyms

SMaRT FVIII (hemophilia A); Factor VIII modulator (SMaRT), Intronn; Factor VIII modulator (SMaRT), VIRxSYS; Hemophilia therapeutic (SMaRT), Intronn; Hemophilia therapeutic (SMaRT), VIRxSYS; SMaRT FVIII (hemophilia A), Intronn; SMaRT FVIII (hemophilia A), VIRxSYS

Indication

Disease Entry	ICD 11	Status	REF
Hemophilia	3B10.0	Investigative	[1]
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Cross-matching ID

TTD ID: D0XK6O

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Coagulation factor VIII (F8)	TT1290U	FA8_HUMAN	Modulator	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease

Hemophilia

ICD Disease Classification

3B10.0

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Coagulation factor VIII (F8)	DTT	F8	1.08E-22	0.89	1.82

Molecular Expression Atlas (MEA)

MEA Detail

Jump to Detail Molecular Expression Atlas of This Drug

References

1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2607).