Details of the Drug

General Information of Drug (ID: DMH4PEY)

Drug Name
Lofepramine
Synonyms Lopramine; DB-2182; Leo-640; WHR-2908A
Indication
Disease Entry ICD 11 Status REF
Major depressive disorder 6A70.3 Approved [1]
ATC Code
N06AA07: Lofepramine
N06AA: Non-selective monoamine reuptake inhibitors
N06A: ANTIDEPRESSANTS
N06: PSYCHOANALEPTICS
N: NERVOUS SYSTEM
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C26H27ClN2O
Canonical SMILES
CN(CCCN1C2=CC=CC=C2CCC3=CC=CC=C31)CC(=O)C4=CC=C(C=C4)Cl
InChI
1S/C26H27ClN2O/c1-28(19-26(30)22-13-15-23(27)16-14-22)17-6-18-29-24-9-4-2-7-20(24)11-12-21-8-3-5-10-25(21)29/h2-5,7-10,13-16H,6,11-12,17-19H2,1H3
InChIKey
SAPNXPWPAUFAJU-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
3947
ChEBI ID
CHEBI:47782
CAS Number
23047-25-8
UNII
OCA4JT7PAW
DrugBank ID
DB13411
TTD ID
D0K3MC

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7551).