Details of the Drug

General Information of Drug (ID: DMH4PEY)

Drug Name
Lofepramine
Synonyms Lopramine; DB-2182; Leo-640; WHR-2908A
Indication
Disease Entry ICD 11 Status REF
Major depressive disorder 6A70.3 Approved [1]
ATC Code
N06AA07: Lofepramine
N06AA: Non-selective monoamine reuptake inhibitors
N06A: ANTIDEPRESSANTS
N06: PSYCHOANALEPTICS
N: NERVOUS SYSTEM
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C26H27ClN2O
Canonical SMILES
CN(CCCN1C2=CC=CC=C2CCC3=CC=CC=C31)CC(=O)C4=CC=C(C=C4)Cl
InChI
InChI=1S/C26H27ClN2O/c1-28(19-26(30)22-13-15-23(27)16-14-22)17-6-18-29-24-9-4-2-7-20(24)11-12-21-8-3-5-10-25(21)29/h2-5,7-10,13-16H,6,11-12,17-19H2,1H3
InChIKey
SAPNXPWPAUFAJU-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
3947
ChEBI ID
CHEMBL87708
CAS Number
23047-25-8
UNII
OCA4JT7PAW
DrugBank ID
DB13411
TTD ID
D0K3MC
Drug-Molecule Activity Atlas (DMA)NEW Click to Jump to the Detailed DMA Information of This Drug
Drug Pharmacogenomic Perturbation (DPP)NEW Click to Jump to the Detailed DPP Information of This Drug
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7551).