Details of the Drug

General Information of Drug (ID: DMH5LME)

Drug Name
Levoleucovorin
Synonyms FUSILEV (TN)
Indication
Disease Entry ICD 11 Status REF
Anemia 3A00-3A9Z Approved [1]
Colon adenocarcinoma N.A. Approved [2]
Colorectal carcinoma N.A. Approved [2]
Non-small-cell lung cancer 2C25.Y Approved [2]
Pervasive developmental disorder 6A00-6A0Z Approved [2]
Pneumocystis pneumonia CA40.20 Approved [2]
Rectal adenocarcinoma 2B92 Approved [2]
Rectum mucinous adenocarcinoma N.A. Approved [2]
Colon cancer 2B90.Z Investigative [2]
Colon mucinous adenocarcinoma N.A. Investigative [2]
Gastric cancer 2B72 Investigative [2]
Megaloblastic anemia N.A. Investigative [2]
Methotrexate toxicity N.A. Investigative [2]
⏷ Show the Full List of Indication(s)
Affected Organisms
Humans and other mammals
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
Chemical Identifiers
Formula
C20H23N7O7
Canonical SMILES
C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
InChI
InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12-,13-/m0/s1
InChIKey
VVIAGPKUTFNRDU-STQMWFEESA-N
Cross-matching ID
PubChem CID
135398559
ChEBI ID
CHEMBL63606
CAS Number
68538-85-2
UNII
990S25980Y
DrugBank ID
DB11596
TTD ID
D0Q6LA
Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Levoleucovorin FDA Label