Details of Disease

General Information of Disease (ID: DISXZXEI)

• Disease Name: Colon mucinous adenocarcinoma
• Synonyms: colloidal adenocarcinoma of colon; mucinous colon adenocarcinoma; colonic colloidal adenocarcinoma; mucinous adenocarcinoma of the colon; colonic mucinous adenocarcinoma; colloid adenocarcinoma of colon; colon colloid adenocarcinoma; colon mucinous adenocarcinoma; mucinous adenocarcinoma of colon; colloid colon adenocarcinoma; colloidal colon adenocarcinoma; colonic colloid adenocarcinoma; colloid adenocarcinoma of the colon; colloidal adenocarcinoma of the colon; colon colloidal adenocarcinoma
• Definition: An invasive adenocarcinoma of the colon characterized by the presence of pools of extracellular mucin. Malignant glandular epithelial cells are present in the mucin collections. Mucin constitutes more than 50% of the lesion.
• Disease Hierarchy:
  DISKNFE8: Mucinous adenocarcinoma
  DISDRE0J: Colon adenocarcinoma
  DISXZXEI: Colon mucinous adenocarcinoma
• Disease Identifiers:
  MONDO ID: MONDO_0005007
  UMLS CUI: C0279639
  MedGen ID: 76007

Drug-Interaction Atlas (DIA) of This Disease

This Disease is Treated as An Indication in 5 Approved Drug(s)

Drug Name	Drug ID	Highest Status	Drug Type	REF
Fluorouracil	DMUM7HZ	Approved	Small molecular drug	[1]
Gefitinib	DM15F0X	Approved	Small molecular drug	[2]
Irinotecan	DMP6SC2	Approved	Small molecular drug	[3]
Leucovorin	DMUAZWG	Approved	Small molecular drug	[4]
Levoleucovorin	DMH5LME	Approved	Small molecular drug	[5]

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 1 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
CHST4	OTESMIW5	Strong	Biomarker	[6]

References

• [1] Fluorouracil FDA Label
• [2] Gefitinib FDA Label
• [3] Irinotecan FDA Label
• [4] Leucovorin FDA Label
• [5] Levoleucovorin FDA Label
• [6] Ectopic expression of a GlcNAc 6-O-sulfotransferase, GlcNAc6ST-2, in colonic mucinous adenocarcinoma.Glycobiology. 2002 Jun;12(6):379-88. doi: 10.1093/glycob/12.6.379.