Details of the Drug

General Information of Drug (ID: DMHJTR2)

Drug Name
XL880
Synonyms GSK 089; GSK 1363089; GSK1363089; XL 880; GSK1363089, GSK089, foretinib, EXEL-2880, XL880; 88Z; MET inhibitors
Indication
Disease Entry ICD 11 Status REF
Breast cancer 2C60-2C65 Phase 2 [1]
Gastric adenocarcinoma 2B72 Phase 2 [2]
Renal cell carcinoma 2C90 Phase 2 [2]
Squamous head and neck cell carcinom 2D60.0 Phase 2 [2]
Solid tumour/cancer 2A00-2F9Z Phase 1 [2]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 3 Molecular Weight (mw) 632.7
Logarithm of the Partition Coefficient (xlogp) 5.5
Rotatable Bond Count (rotbonds) 12
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 10
Chemical Identifiers
Formula
C34H34F2N4O6
IUPAC Name
1-N'-[3-fluoro-4-[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
Canonical SMILES
COC1=CC2=C(C=CN=C2C=C1OCCCN3CCOCC3)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F
InChI
InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)
InChIKey
CXQHYVUVSFXTMY-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
42642645
ChEBI ID
CHEBI:91418
CAS Number
849217-64-7
UNII
81FH7VK1C4
DrugBank ID
DB12307
TTD ID
D0D1GF
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Proto-oncogene c-Met (MET) TTNDSF4 MET_HUMAN Modulator [3]
Vascular endothelial growth factor receptor 2 (KDR) TTUTJGQ VGFR2_HUMAN Modulator [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Hepatocyte growth factor receptor (MET) OT7K55MU MET_HUMAN Post-Translational Modifications [4]
Proto-oncogene tyrosine-protein kinase Src (SRC) OTETYX40 SRC_HUMAN Post-Translational Modifications [4]
Tyrosine-protein kinase receptor UFO (AXL) OTKA2SUX UFO_HUMAN Gene/Protein Processing [5]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Breast cancer
ICD Disease Classification 2C60-2C65
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Vascular endothelial growth factor receptor 2 (KDR) DTT KDR 1.98E-01 0.11 0.2
Proto-oncogene c-Met (MET) DTT MET 1.08E-03 -0.24 -0.4
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 -0.9542 4.6482 -1.764 44.6856
ES7 GDSC1; GDSC2 -3.5313 -0.7352 -3.5429 67.7691
H-EMC-SS GDSC1; GDSC2 -2.6923 0.9621 -2.7794 59.3122
NOS-1 [Human HNSCC] GDSC1; GDSC2 -2.5263 0.4175 -2.5599 58.2487
ES1 GDSC1; GDSC2 -2.2497 -0.5856 -2.2507 55.8941
SK-PN-DW GDSC1; GDSC2 -2.178 -0.7295 -2.1783 55.1863
ES5 GDSC1; GDSC2 -1.9717 1.2365 -2.0475 52.9214
EW-18 GDSC1; GDSC2 -1.3057 1.0029 -1.3311 46.5016
SK-N-MC CTRP2 -1.2641 -0.8272 -1.2641 48.6905
ES8 GDSC1; GDSC2 -1.2145 1.4856 -1.2743 45.6795
CADO-ES1 GDSC1; GDSC2 -1.115 0.5477 -1.1193 44.5418
EW-11 GDSC1; GDSC2 -1.0357 2.6682 -1.2724 44.3616
MHH-ES-1 GDSC1; GDSC2; CTRP2 -0.9901 1.0703 -0.9911 46.867
EW-7 GDSC1; GDSC2 -0.9844 0.9827 -0.9989 43.2717
CHSA8926 GDSC1; GDSC2 -0.9454 2.8669 -1.2192 43.6105
EW-13 GDSC1 -0.8967 1.072 -0.943 40.8981
HuO9 GDSC1; GDSC2 -0.8231 2.034 -0.9262 41.976
SK-ES-1 GDSC1; GDSC2; CTRP2 -0.7106 1.4535 -0.7127 45.0082
EW-1 GDSC1; GDSC2 -0.5595 1.4148 -0.5831 39.0596
TC-71 GDSC1; GDSC2 -0.5347 0.7558 -0.5364 38.7099
CAL-78 GDSC1; GDSC2; CTRP2 -0.3832 2.1244 -0.3914 42.8449
EW-22 GDSC2 -0.3328 2.1373 -0.4167 37.0635
EW-12 GDSC2 -0.3 2.0285 -0.3673 36.663
EW-16 GDSC1; GDSC2 -0.1369 2.2169 -0.2185 35.1022
A-673 GDSC1; GDSC2; CTRP2 -0.046 1.7286 -0.0469 40.5779
CHSA0108 GDSC1; GDSC2 -0.0389 3.1798 -0.3081 34.9777
CHSA0011 GDSC1; GDSC2 0.2755 2.8449 0.1143 31.3766
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 0.3346 2.7863 0.3213 38.0824
EW-3 GDSC1; GDSC2 0.3745 3.6076 0.023 31.322
Hs 888.T CTRP2 0.4326 4.8364 0.2025 38.0527
ES6 GDSC1; GDSC2 0.5257 2.8826 0.3781 28.8132
ES4 GDSC1; GDSC2 0.5695 3.7382 0.1949 29.5251
SaOS-2 GDSC1; GDSC2; CTRP2 0.7016 2.3468 0.7004 35.5984
SJSA-1 GDSC1; GDSC2; CTRP2 0.7375 3.1718 0.7192 35.4155
TC71 CTRP2 0.7799 1.6409 0.7799 35.0728
U2OS GDSC1; GDSC2; CTRP2 0.9895 3.6049 0.9559 33.7872
SW1353 CTRP2 1.1466 5.2859 0.8856 33.471
NY GDSC1; GDSC2 1.2221 3.8128 0.8797 22.8989
EW-24 GDSC1; GDSC2 1.6182 2.4054 1.6121 17.1276
Hs 822.T CTRP2 1.7292 3.8629 1.7066 28.8241
HOS GDSC1; GDSC2; CTRP2 1.7445 2.985 1.7439 28.6484
HuO-3N1 GDSC1; GDSC2 1.8931 6.5103 0.4226 22.6219
CAL-72 GDSC1; GDSC2 2.1029 2.9733 2.068 12.4117
MG-63 GDSC1; GDSC2; CTRP2 2.2669 3.3582 2.2664 25.168
U-CH2 GDSC2 2.3126 7.326 0.4271 21.0429
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 220 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 -4.4792 1.1681 -4.5635 67.6381
MEC1 CTRP2 0.1691 2.7723 0.1525 39.194
JM1 GDSC1; GDSC2; CTRP2 -0.4453 1.266 -0.4457 43.2368
MV4-11 GDSC1; GDSC2; CTRP2 -12.5186 -3.7512 -12.594 91.1093
MOLM-16 GDSC2; CTRP2 -10.9468 0.6274 -11.3496 83.0244
EoL-1 GDSC1; GDSC2; CTRP2 -10.8528 -9.3572 -10.8528 99.725
MOLM-13 GDSC1; GDSC2; CTRP2 -10.3273 -7.5052 -10.3273 97.4547
Mono-Mac-6 GDSC1; GDSC2; CTRP2 -8.6507 4.6574 -9.6364 74.3844
Kasumi-1 GDSC2; CTRP2 -7.26 -1.4443 -7.2945 81.3105
SEM CTRP2 -7.1232 1.439 -7.3802 76.0184
NKM-1 GDSC1; GDSC2 -6.6406 -4.1497 -6.641 92.1037
Mono-Mac-1 CTRP2 -5.1516 6.7498 -6.3738 64.3903
GDM-1 GDSC1; GDSC2 -5.0662 -0.8504 -5.114 77.4014
ALL-PO GDSC1; GDSC2 -4.5974 -0.3607 -4.6598 74.0354
MOLM-6 CTRP2 -3.9108 0.1609 -3.928 65.5987
NCO2 CTRP2 -3.6642 -1.1986 -3.6646 64.6154
OCI-AML-5 GDSC1; GDSC2; CTRP2 -3.5768 -0.7706 -3.5781 63.9778
MEG-01 GDSC1; GDSC2 -3.535 -1.3717 -3.5368 68.4074
ALL-SIL GDSC1; GDSC2; CTRP2 -3.3047 -1.3794 -3.3048 62.2762
Ku812 GDSC1; GDSC2; CTRP2 -3.1692 -1.1554 -3.1693 61.3717
LAMA-84 GDSC1; GDSC2; CTRP2 -3.1206 -1.3106 -3.1206 58.2741
SU-DHL-16 GDSC1; GDSC2 -2.9865 -2.5137 -2.9865 63.3058
BV-173 GDSC1; GDSC2; CTRP2 -2.9159 0.1389 -2.9203 59.5909
WSU-NHL GDSC1; GDSC2 -2.8459 -0.8483 -2.848 61.7662
JURL-MK1 GDSC1; GDSC2; CTRP2 -2.8358 -1.3557 -2.8358 59.1609
CML-T1 GDSC2; CTRP2 -2.5889 -0.396 -2.5893 57.5066
SU-DHL-5 GDSC1; GDSC2 -2.4875 -0.9894 -2.4878 58.2845
697 GDSC1; GDSC2; CTRP2 -2.4748 -1.4274 -2.4748 56.756
EM-2 GDSC1; GDSC2; CTRP2 -2.4359 -0.3913 -2.4361 56.492
Peer CTRP2 -2.4147 -0.2422 -2.4151 56.3485
BE-13 GDSC1; GDSC2 -2.3605 -0.1064 -2.3685 56.907
KYO-1 CTRP2 -2.2828 -0.3246 -2.2829 55.4742
P32/ISH GDSC1; GDSC2 -2.2692 -0.9426 -2.2693 56.1038
MY-M12 GDSC1; GDSC2 -2.2329 0.1959 -2.2473 55.6123
Karpas-45 GDSC1; GDSC2 -2.073 -0.1686 -2.0764 54.1115
RS4;11 GDSC1; GDSC2; CTRP2 -2.0555 -0.2081 -2.0556 53.9617
CCRF-CEM GDSC1; GDSC2 -1.9295 -1.0015 -1.9295 52.6981
MOLT-16 GDSC1; GDSC2; CTRP2 -1.7941 -0.0509 -1.7941 52.2206
SUP-B8 GDSC2 -1.7891 0.2036 -1.7955 51.2786
NALM-6 GDSC1; GDSC2; CTRP2 -1.7253 -0.502 -1.7253 51.7632
P30/OHK GDSC1; GDSC2 -1.6922 0.0589 -1.6951 50.3156
CTV-1 GDSC1; GDSC2 -1.6537 -0.003 -1.6557 49.931
OCI-Ly19 GDSC1; GDSC2; CTRP2 -1.5585 1.0801 -1.5628 50.6492
SUP-M2 GDSC1; GDSC2; CTRP2 -1.553 -0.4196 -1.553 50.6147
Loucy GDSC1; GDSC2 -1.52 -0.0347 -1.521 48.5906
SUP-B15 GDSC1; GDSC2; CTRP2 -1.5037 -0.3392 -1.5037 50.2865
KMS-11 GDSC1; GDSC2; CTRP2 -1.4644 3.564 -1.6303 50.0232
MOLT-3 CTRP2 -1.4639 -1.0348 -1.4639 50.0213
K-562 GDSC1; GDSC2; CTRP2 -1.4492 0.1174 -1.4492 49.9231
Mino CTRP2 -1.4237 -1.0615 -1.4237 49.7538
RPMI-8402 GDSC1; GDSC2; CTRP2 -1.4219 0.6935 -1.4228 49.7419
ST486 GDSC1; GDSC2; CTRP2 -1.4007 0.4439 -1.401 49.6007
A4/Fukuda GDSC1; GDSC2; CTRP2 -1.3977 2.3253 -1.4391 49.5899
KCL-22 GDSC1; GDSC2; CTRP2 -1.3857 0.2659 -1.3858 49.5004
MOLT-4 GDSC1; GDSC2 -1.3592 0.0492 -1.3601 46.9782
HAL-01 GDSC1; GDSC2 -1.3156 1.3079 -1.3638 46.6447
PF-382 GDSC1; GDSC2 -1.3026 0.4428 -1.3073 46.4214
KE-37 GDSC1; GDSC2; CTRP2 -1.2835 -0.1534 -1.2835 48.8195
KG-1 GDSC1; GDSC2 -1.2702 1.4124 -1.3257 46.215
P12-Ichikawa GDSC1; GDSC2; CTRP2 -1.2479 -0.5232 -1.2479 48.5824
Pfeiffer CTRP2 -1.2327 0.7556 -1.2333 48.4819
NB4 GDSC1; GDSC2 -1.1997 1.4764 -1.2578 45.5307
Reh GDSC1; GDSC2 -1.1793 0.4257 -1.1824 45.1819
MHH-PREB-1 GDSC1; GDSC2 -1.1581 0.8787 -1.1727 45.006
RL GDSC1; GDSC2; CTRP2 -1.1527 2.1338 -1.1769 47.9754
DoHH2 GDSC2; CTRP2 -1.0991 -0.1291 -1.0991 47.5909
MOLT-13 GDSC1; GDSC2 -1.064 0.09 -1.0642 44.014
OCI-AML-2 GDSC1; GDSC2 -1.0392 -0.2366 -1.0393 43.7648
VAL GDSC1; GDSC2 -0.9894 1.3373 -1.0249 43.3935
QIMR-WIL GDSC1; GDSC2 -0.9613 2.2017 -1.1012 43.4255
Sc-1 GDSC1 -0.9509 1.4646 -1.0544 41.809
NOMO-1 GDSC1; GDSC2 -0.9453 3.7245 -1.4509 44.096
RCH-ACV GDSC2; CTRP2 -0.9138 2.5685 -0.9526 46.4208
KOPN-8 GDSC1; GDSC2 -0.9051 0.5508 -0.9074 42.4292
ML-2 GDSC1; GDSC2 -0.8815 0.6306 -0.8845 42.1952
SIG-M5 GDSC1; GDSC2; CTRP2 -0.8707 -0.0457 -0.8707 46.0691
SR GDSC1; GDSC2; CTRP2 -0.7081 0.4904 -0.7081 44.9862
AML-193 CTRP2 -0.7037 3.1614 -0.778 45.1006
Ki-JK CTRP2 -0.6658 2.2181 -0.6815 44.7412
Farage GDSC1; GDSC2 -0.6564 1.3542 -0.6798 40.0278
CESS GDSC1; GDSC2 -0.6305 2.4146 -0.7819 40.2632
KO52 CTRP2 -0.6148 1.6011 -0.6175 44.3719
GA-10 GDSC2; CTRP2 -0.6096 2.5329 -0.6366 44.3926
U-937 CTRP2 -0.5733 5.0914 -0.9416 44.7085
SUP-T11 CTRP2 -0.5361 3.152 -0.6014 43.9861
Kasumi-2 CTRP2 -0.5242 2.8233 -0.5646 43.8566
MJ CTRP2 -0.4811 3.1063 -0.54 43.6117
EB1 CTRP2 -0.4791 3.6263 -0.5896 43.702
EB2 GDSC1; GDSC2 -0.4661 2.6395 -0.6478 38.776
Daudi GDSC1; GDSC2; CTRP2 -0.4622 1.2352 -0.4625 43.3488
VL51 GDSC1; GDSC2 -0.4474 1.6613 -0.4845 37.9981
GR-ST GDSC1; GDSC2 -0.4409 1.8608 -0.497 38.0174
CA46 GDSC1; GDSC2; CTRP2 -0.4236 1.912 -0.4284 43.1042
TK [Human B-cell lymphoma] GDSC1; GDSC2 -0.4017 2.5558 -0.5612 38.061
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 -0.3524 1.9586 -0.3572 42.6302
BC-1 GDSC1; GDSC2 -0.3416 3.0365 -0.602 37.8719
Ri-1 CTRP2 -0.3274 3.2803 -0.3938 42.6166
MOLP-8 GDSC1; GDSC2; CTRP2 -0.3173 2.6915 -0.3434 42.4533
KMS-21-BM CTRP2 -0.3126 3.211 -0.3724 42.5039
SU-DHL-10 GDSC1; GDSC2; CTRP2 -0.3002 0.9006 -0.3002 42.2688
P31/FUJ GDSC1; GDSC2; CTRP2 -0.2947 0.5228 -0.2947 42.2322
SU-DHL-6 GDSC1; GDSC2; CTRP2 -0.2544 1.0146 -0.2545 41.9639
F-36P CTRP2 -0.2374 9.7347 -2.0809 44.4862
OPM-2 GDSC1; GDSC2; CTRP2 -0.2316 1.5092 -0.2322 41.8133
KHM-1B CTRP2 -0.2163 2.2994 -0.2259 41.7381
A3/Kawakami GDSC1; GDSC2; CTRP2 -0.1971 2.397 -0.2089 41.6164
JVM-3 GDSC1; GDSC2; CTRP2 -0.1506 2.9224 -0.1836 41.3653
BONNA-12 GDSC2 -0.1409 3.0133 -0.3776 35.8319
TUR GDSC1; GDSC2 -0.1099 2.2295 -0.1915 34.8329
JSC-1 GDSC1; GDSC2 -0.1094 2.1905 -0.1855 34.802
WIL2 NS GDSC1; GDSC2 -0.0824 2.173 -0.1543 34.5122
H9 GDSC1; GDSC2 -0.0763 3.6124 -0.4699 35.8581
MC116 GDSC1; GDSC2; CTRP2 -0.0639 2.011 -0.0668 40.7036
SCC-3 GDSC1; GDSC2 -0.0637 0.7515 -0.0638 33.9758
SU-DHL-1 GDSC1; GDSC2; CTRP2 -0.0624 0.3029 -0.0624 40.6844
Ramos.2G6.4C10 GDSC1; GDSC2 -0.0553 1.7923 -0.0851 34.0381
YT GDSC1; GDSC2 -0.0512 1.7892 -0.0805 33.9947
OCI-Ly7 GDSC2 -0.0486 1.5174 -0.0611 33.8855
RPMI-6666 GDSC1; GDSC2; CTRP2 -0.0459 3.3095 -0.1015 40.7317
MM1.S GDSC2; CTRP2 -0.0066 2.1985 -0.0114 40.3277
KE-97 CTRP2 -0.0022 2.3015 -0.0087 40.3035
BC-3 GDSC1; GDSC2 0.0878 1.9903 0.0474 32.656
JeKo-1 GDSC2; CTRP2 0.0918 3.2662 0.0456 39.7937
BL-70 CTRP2 0.1059 2.279 0.101 39.5789
ARH-77 GDSC1; GDSC2 0.1078 3.0824 -0.1233 33.3705
KMS-34 CTRP2 0.1139 1.8672 0.113 39.5128
Karpas-299 GDSC1; GDSC2 0.1572 1.5763 0.1477 31.806
Namalwa GDSC1; GDSC2; CTRP2 0.1599 2.9904 0.1335 39.2845
PL-21 GDSC1; GDSC2 0.182 3.5178 -0.1602 33.1544
BDCM CTRP2 0.2053 2.3155 0.201 38.9148
HH [Human lymphoma] GDSC1; GDSC2; CTRP2 0.2079 2.934 0.1856 38.9533
SU-DHL-4 GDSC1; GDSC2; CTRP2 0.2464 2.6813 0.2347 38.6643
DND-41 GDSC1; GDSC2 0.2545 2.4369 0.1679 31.2162
KMS-18 CTRP2 0.2853 2.0409 0.2842 38.3715
DEL GDSC1; GDSC2; CTRP2 0.2857 1.9967 0.2848 38.3681
THP-1 GDSC1; GDSC2; CTRP2 0.2942 4.1628 0.1647 38.6871
NCI-H929 GDSC2 0.2989 2.4437 0.2145 30.7612
PL21 CTRP2 0.3249 2.2445 0.3223 38.1126
MLMA GDSC1; GDSC2 0.3299 3.035 0.1303 31.0242
SU-DHL-8 GDSC1; GDSC2; CTRP2 0.3321 4.1467 0.2074 38.4244
ATN-1 GDSC1; GDSC2 0.3493 3.2353 0.1011 31.0707
HL-60 GDSC1; GDSC2; CTRP2 0.3708 2.3688 0.3673 37.8098
CMK CTRP2 0.3811 1.9107 0.3807 37.7313
BALL-1 GDSC1; GDSC2 0.3947 3.6043 0.046 31.1105
M-07e CTRP2 0.399 4.5104 0.2243 38.1226
RPMI-8866 GDSC1; GDSC2 0.4217 3.5719 0.0852 30.7875
IM-9 GDSC2 0.4722 4.9264 -0.3367 32.4589
Hs 611.T CTRP2 0.4981 3.1113 0.4759 37.0217
SUP-HD1 GDSC1; GDSC2; CTRP2 0.5029 3.3543 0.4671 37.0327
HuT 78 CTRP2 0.5294 4.5978 0.35 37.2807
JVM-2 GDSC1; GDSC2 0.5739 3.8543 0.1623 29.6651
EJM GDSC1; GDSC2; CTRP2 0.5941 3.6075 0.5435 36.4721
Jiyoye GDSC1 0.5959 1.682 0.5686 22.1761
MHH-CALL-4 GDSC2; CTRP2 0.6011 2.9529 0.588 36.3067
Hs 445 GDSC1; GDSC2 0.6021 2.0256 0.583 27.3902
LC4-1 GDSC1; GDSC2 0.6075 3.2433 0.3807 28.4028
CTB-1 GDSC1; GDSC2 0.63 3.5834 0.3088 28.6617
SUP-T1 GDSC1; GDSC2; CTRP2 0.6533 3.2461 0.6291 35.9949
KMOE-2 GDSC1; GDSC2 0.6812 2.4642 0.6208 26.8077
HuNS1 CTRP2 0.7032 4.239 0.5908 35.9384
DG-75 GDSC1; GDSC2 0.7832 2.1519 0.7624 25.582
Granta-519 GDSC1; GDSC2; CTRP2 0.7843 2.896 0.7762 35.0704
SKM-1 GDSC2; CTRP2 0.8086 3.057 0.7964 34.9222
SK-MM-2 GDSC1; GDSC2; CTRP2 0.8246 4.3073 0.7111 35.1379
NU-DUL-1 GDSC1; GDSC2; CTRP2 0.8291 3.1356 0.8146 34.7932
KY821 GDSC1; GDSC2 0.8452 2.8354 0.7346 25.4236
KMS-12-BM GDSC1; GDSC2; CTRP2 0.866 3.8608 0.8063 34.6939
Karpas-422 GDSC1; GDSC2; CTRP2 0.8782 2.7606 0.8741 34.4316
MHH-CALL-2 GDSC2 0.9027 2.3175 0.8733 24.4261
KMS-28BM CTRP2 0.9052 3.2878 0.8864 34.3
KMS-27 CTRP2 0.9162 4.1653 0.8268 34.4547
CRO-AP2 GDSC2 0.9855 5.0707 0.1477 27.8137
Karpas-1106P GDSC2 1.0037 3.9012 0.613 25.3286
OCI-M1 GDSC1; GDSC2; CTRP2 1.0122 3.0648 1.0036 33.5538
U-698-M GDSC1; GDSC2 1.0173 3.7197 0.688 24.8653
L-540 GDSC1; GDSC2; CTRP2 1.0178 4.2145 0.9287 33.7791
OCI-AML-3 GDSC1; GDSC2; CTRP2 1.0216 3.4365 0.999 33.5373
AMO1 GDSC1; GDSC2; CTRP2 1.1031 3.3655 1.0863 32.9755
HC-1 GDSC1; GDSC2 1.1211 5.5303 0.0945 27.4721
HPB-ALL CTRP2 1.1471 3.4552 1.1274 32.692
WSU-DLCL2 GDSC1; GDSC2; CTRP2 1.183 2.7728 1.1812 32.3934
Toledo CTRP2 1.2456 4.6213 1.116 32.3977
KMS-20 CTRP2 1.2541 3.6271 1.2288 31.998
Ci-1 CTRP2 1.2954 3.2001 1.2881 31.6628
JJN-3 GDSC1; GDSC2; CTRP2 1.3146 3.059 1.3105 31.5245
LP-1 GDSC1; GDSC2; CTRP2 1.3241 2.963 1.3215 31.4559
MN-60 GDSC1; GDSC2 1.3549 3.1861 1.2108 20.4927
MOTN-1 CTRP2 1.4616 3.1786 1.4572 30.5462
L-363 GDSC1; GDSC2; CTRP2 1.4724 3.9657 1.4328 30.5916
HD-MY-Z CTRP2 1.5643 3.4717 1.5544 29.8802
RPMI-8226 GDSC1; GDSC2; CTRP2 1.6029 4.5194 1.5126 29.8927
HT GDSC1; GDSC2; CTRP2 1.6625 3.6839 1.6469 29.2452
DB GDSC1; GDSC2; CTRP2 1.6992 3.1776 1.6971 28.9554
NK-92MI GDSC2 1.7355 4.413 1.2062 18.8493
HDLM-2 GDSC1; GDSC2 1.8055 2.8528 1.7675 15.4123
OCI-Ly3 CTRP2 1.9347 5.4796 1.7 28.177
MHH-CALL-3 CTRP2 1.9902 5.9169 1.6541 28.1561
NU-DHL-1 CTRP2 2.0601 3.7969 2.0499 26.5779
U266B1 GDSC1; GDSC2; CTRP2 2.1401 5.5668 1.9038 26.8195
Karpas-620 GDSC1; GDSC2; CTRP2 2.1583 6.0821 1.793 27.1454
SET-2 CTRP2 2.2531 3.0165 2.2531 25.258
TF-1 CTRP2 2.2696 4.4564 2.2258 25.2957
KM-H2 GDSC1; GDSC2; CTRP2 2.287 7.693 1.0518 24.457
Raji GDSC1; GDSC2 2.3681 4.9235 1.6335 13.8254
HEL 92.1.7 CTRP2 2.4451 2.9369 2.4451 23.979
L-428 GDSC1; GDSC2; CTRP2 2.4815 4.1577 2.4674 23.7838
Karpas-231 GDSC2 2.4915 4.3484 2.0193 11.0294
RC-K8 GDSC1; GDSC2 2.6633 4.7486 2.0058 10.468
BL-41 GDSC1; GDSC2; CTRP2 2.9583 9.7913 1.2333 26.6498
L-1236 GDSC1; GDSC2; CTRP2 3.1316 9.0629 1.7314 28.0083
REC-1 CTRP2 3.1365 5.3422 3.0314 19.7319
OCI-Ly10 CTRP2 3.1909 8.8808 1.8715 23.8023
EHEB CTRP2 3.3112 10.9155 1.0754 26.1844
ROS-50 GDSC1; GDSC2 3.3705 9.5216 0.2625 18.4554
MOLP-2 CTRP2 3.5472 5.7118 3.4022 17.1373
ME1 GDSC1; GDSC2 3.8516 9.7279 0.5489 15.5515
P3HR-1 CTRP2 4.9197 11.8531 2.1567 18.3937
ME1 CTRP2 5.4113 10.8746 3.0833 13.674
HEL GDSC1; GDSC2; CTRP2 7.6319 15.5303 1.7696 9.9251
Jurkat GDSC2; CTRP2 8.2265 15.6362 2.1072 7.7663
⏷ Show the Full List of 220 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 -0.0846 1.9473 -0.0871 40.8402
TE15 CTRP2 1.0314 4.0733 0.9592 33.6343
OE33 GDSC1; GDSC2; CTRP2 -0.9556 4.6665 -1.2676 46.9767
TE-8 GDSC1; GDSC2 -0.592 2.2554 -0.7126 39.7746
T.T GDSC1; GDSC2 -0.3334 1.2098 -0.3411 36.7196
KYSE-270 GDSC1; GDSC2 -0.0981 1.7403 -0.1257 34.4568
TE-11 GDSC1; GDSC2; CTRP2 0.7196 1.8728 0.7195 35.4749
KYSE-140 GDSC1; GDSC2; CTRP2 0.8371 4.2812 0.7279 35.0415
KYSE-150 GDSC1; GDSC2; CTRP2 1.0434 3.4802 1.0192 33.3976
KYSE-520 GDSC1; GDSC2; CTRP2 1.149 3.0763 1.1425 32.6355
KYSE-410 GDSC1; GDSC2; CTRP2 1.1539 3.3936 1.1373 32.6364
TE-6 GDSC1; GDSC2; CTRP2 1.2728 3.6287 1.248 31.8716
KYSE-450 GDSC1; GDSC2; CTRP2 1.2948 4.5199 1.1837 32.0106
TE-15 GDSC1; GDSC2 1.622 4.6585 0.9859 20.5797
TE-9 GDSC1; GDSC2; CTRP2 1.6291 2.8739 1.6286 29.417
EC-GI-10 GDSC1; GDSC2; CTRP2 1.6642 3.722 1.6469 29.2391
TE-1 GDSC1; GDSC2; CTRP2 1.6799 4.2575 1.6244 29.2629
OE21 GDSC1; GDSC2; CTRP2 1.7053 2.8164 1.7051 28.9081
KYSE-30 CTRP2 1.7894 3.7596 1.774 28.399
TE-4 GDSC1; GDSC2; CTRP2 1.8833 3.323 1.881 27.7294
TE-14 CTRP2 1.9232 4.0632 1.8953 27.5493
TE-10 GDSC1; GDSC2; CTRP2 2.0747 5.7508 1.7887 27.4247
TE-5 GDSC1; GDSC2; CTRP2 2.2293 2.962 2.2293 25.4167
OE19 GDSC1; GDSC2; CTRP2 2.3926 3.3795 2.3923 24.3297
COLO 680N GDSC1; GDSC2; CTRP2 2.721 4.1878 2.7119 22.1713
KYSE-510 GDSC1; GDSC2; CTRP2 2.8372 5.2681 2.7216 21.7616
KYSE-70 GDSC1; GDSC2; CTRP2 3.3683 6.8896 2.8562 19.6653
KYSE-180 GDSC1; GDSC2; CTRP2 6.1485 14.1223 2.0919 16.0412
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 2.3241 3.2543 2.324 24.7857
MZ-PC-1 GDSC1; GDSC2 -2.4445 0.8112 -2.5038 57.3177
Panc 02.03 GDSC1; GDSC2; CTRP2 -0.9373 2.7319 -0.9876 46.5916
KP-4 GDSC1; GDSC2; CTRP2 -0.8812 3.1334 -0.9619 46.266
Panc 08.13 GDSC1; GDSC2; CTRP2 -0.7736 3.6785 -0.9091 53.4228
PL4 GDSC1; GDSC2 -0.4452 2.5849 -0.614 38.5226
HuP-T4 GDSC1; GDSC2; CTRP2 -0.2784 4.2861 -0.4676 42.5582
HPAC GDSC1; GDSC2; CTRP2 -0.0221 3.2662 -0.0732 40.562
KP-2 GDSC1; GDSC2; CTRP2 0.0899 1.8568 0.0889 39.6731
Panc 05.04 CTRP2 0.1778 13.5102 -3.2544 44.0212
DAN-G GDSC1; GDSC2; CTRP2 0.3545 2.3028 0.3516 37.9166
HPAF-II GDSC1; GDSC2; CTRP2 0.5547 3.8362 0.4809 36.8048
BxPC-3 GDSC1; GDSC2; CTRP2 0.5999 2.5423 0.5962 36.2842
Capan-2 GDSC1; GDSC2; CTRP2 0.712 3.774 0.6526 35.7162
PaTu 8988t GDSC1; GDSC2; CTRP2 0.9222 2.8935 0.9163 34.1445
PK-59 CTRP2 1.1514 4.7558 0.9931 33.1149
Capan-1 GDSC1; GDSC2; CTRP2 1.3408 3.8665 1.3031 31.4617
Hs 766T GDSC1; GDSC2; CTRP2 1.3415 3.164 1.3358 31.3505
PK-45H CTRP2 1.4729 5.8836 1.0984 31.6881
AsPC-1 GDSC1; GDSC2; CTRP2 1.5116 5.3871 1.2603 31.034
Panc 10.05 GDSC1; GDSC2; CTRP2 1.5204 4.7178 1.3959 30.5556
MIA PaCa-2 GDSC1; GDSC2; CTRP2 1.5775 2.5486 1.5775 29.7591
PaTu 8988s CTRP2 1.6063 3.6592 1.5903 29.6208
SU.86.86 GDSC1; GDSC2; CTRP2 1.6828 4.0606 1.645 29.1844
SNU-213 CTRP2 1.817 8.4156 0.6205 31.9992
PSN1 GDSC1; GDSC2; CTRP2 1.9022 3.041 1.9019 27.5969
HuP-T3 GDSC1; GDSC2; CTRP2 1.9757 5.1215 1.8177 27.6427
Panc 03.27 GDSC1; GDSC2; CTRP2 2.023 3.987 2.0033 26.857
PaTu 8902 GDSC1; GDSC2; CTRP2 2.0585 4.8036 1.9597 26.8888
KP-1N GDSC2 2.1004 5.1304 1.271 17.0118
YAPC GDSC1; GDSC2; CTRP2 2.2364 5.8944 1.9286 26.4289
SW1990 GDSC1; GDSC2; CTRP2 2.2484 3.2061 2.2483 25.2896
Panc 04.03 GDSC1; GDSC2; CTRP2 2.2664 4.8545 2.1747 25.4803
TCC-Pan2 CTRP2 2.2708 6.2741 1.8612 26.5557
KP-3 GDSC1; GDSC2; CTRP2 2.3582 6.0667 2.0155 25.7436
CFPAC-1 GDSC1; GDSC2; CTRP2 2.4096 5.6018 2.1892 24.9738
SNU-410 CTRP2 2.4383 5.0319 2.332 24.386
QGP-1 GDSC1; GDSC2; CTRP2 3.4815 10.624 1.3794 24.7239
L3.3 CTRP2 3.9763 7.0629 3.4458 15.7098
SUIT-2 GDSC1; GDSC2; CTRP2 6.1516 12.4167 2.9471 12.719
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 74 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 2.2012 3.3802 2.2004 25.6068
COLO 792 GDSC1; GDSC2; CTRP2 -1.6234 5.1187 -2.0903 50.9112
A-431 GDSC1; GDSC2 -1.341 0.1046 -1.3421 46.7962
WM35 GDSC1; GDSC2 -1.3305 0.4046 -1.3348 46.6996
CHL-1 GDSC1; GDSC2 -1.2642 0.2428 -1.2659 46.0282
VMRC-MELG GDSC1; GDSC2 -1.1341 1.8824 -1.237 44.9958
IST-MEL1 GDSC1; GDSC2 -0.8203 0.3353 -0.8207 41.5692
M14 GDSC1; GDSC2 -0.8029 2.445 -0.9741 41.9943
WM278 GDSC1; GDSC2 -0.6453 1.3985 -0.6711 39.9274
MZ-MEL-7 GDSC1; GDSC2 -0.363 2.8031 -0.5707 37.8744
IGR-1 GDSC1; GDSC2; CTRP2 -0.1929 2.0218 -0.197 41.5664
CP50-MEL-B GDSC1; GDSC2 -0.0837 1.9247 -0.1268 34.3876
WM115 GDSC1; GDSC2; CTRP2 0.0333 1.846 0.0321 40.0507
A101D GDSC1; GDSC2; CTRP2 0.0924 2.3131 0.0868 39.6708
LOX-IMVI GDSC1; GDSC2; CTRP2 0.1524 1.9611 0.1512 39.2572
WM266-4 CTRP2 0.1696 3.5074 0.1073 39.3236
G-mel GDSC1; GDSC2 0.2131 1.6182 0.2033 31.2465
451Lu GDSC1; GDSC2 0.3016 2.8509 0.1414 31.1119
Hs 839.T CTRP2 0.3396 5.4247 -0.0238 38.9902
MZ-MEL-2 GDSC1; GDSC2 0.342 2.3432 0.2754 30.2402
SH-4 GDSC1; GDSC2 0.3513 2.7341 0.2195 30.4744
SK-MEL-24 GDSC1; GDSC2; CTRP2 0.3997 2.4458 0.3953 37.6203
Hs 895.T CTRP2 0.4351 6.0559 -0.0804 38.7468
HT-144 GDSC1; GDSC2; CTRP2 0.4688 2.9062 0.4543 37.1924
COLO 829 GDSC1; GDSC2; CTRP2 0.5515 2.523 0.5475 36.6076
SK-MEL-3 GDSC1; GDSC2; CTRP2 0.6497 3.0483 0.6342 35.9907
Malme-3M CTRP2 0.6986 4.1503 0.5973 35.935
RPMI-7951 GDSC1; GDSC2; CTRP2 0.7378 2.7815 0.7316 35.374
GAK GDSC1; GDSC2 0.7717 1.365 0.7717 25.592
A-388 GDSC1; GDSC2 0.8026 3.6446 0.4781 26.971
DJM-1 GDSC1; GDSC2 0.873 4.2743 0.3399 27.3588
Hs 852.T CTRP2 0.9 5.8121 0.4918 35.515
A2058 GDSC1; GDSC2; CTRP2 0.9444 2.6934 0.9418 33.9857
Hs 938.T GDSC1; GDSC2 0.9447 1.7812 0.9433 23.8627
A-375 GDSC1; GDSC2; CTRP2 1.1022 3.582 1.0743 33.0181
WM88 CTRP2 1.1452 4.401 1.0404 32.9839
G-361 GDSC1; GDSC2; CTRP2 1.1879 3.636 1.1597 32.4484
COLO 800 GDSC1; GDSC2; CTRP2 1.198 3.7927 1.1596 32.4149
Hs 944.T CTRP2 1.2963 4.3577 1.207 31.9287
IPC-298 GDSC1; GDSC2; CTRP2 1.3494 3.214 1.3427 31.3008
IGR-37 GDSC1; GDSC2; CTRP2 1.3577 3.7366 1.3295 31.3176
WT2-iPS GDSC1; GDSC2; CTRP2 1.385 2.1707 1.385 31.0414
SK-MEL-5 GDSC1; GDSC2; CTRP2 1.4128 3.1213 1.4088 30.87
LB2518-MEL GDSC1; GDSC2 1.434 2.6513 1.3985 19.1268
COLO 783 GDSC1; GDSC2 1.4879 3.121 1.3715 19.0116
HMCB CTRP2 1.5179 2.8451 1.5172 30.1585
Hs 294T CTRP2 1.5196 3.488 1.5082 30.1828
Hs 940.T GDSC1; GDSC2; CTRP2 1.5208 3.1867 1.517 30.1495
LB373-MEL-D GDSC1; GDSC2 1.5458 5.9334 0.3481 24.3924
COLO 679 GDSC1; GDSC2 1.6273 4.359 1.1136 19.8316
MMAc-SF GDSC1; GDSC2 1.6295 3.8395 1.3116 18.7015
SK-MEL-28 GDSC1; GDSC2; CTRP2 1.6568 3.6691 1.6417 29.2815
UACC-62 GDSC1; GDSC2; CTRP2 1.665 2.2044 1.665 29.1762
MDA-MB-435S CTRP2 1.6842 5.2205 1.4829 29.7255
WM1552C GDSC1; GDSC2 1.7747 2.4627 1.7702 15.549
IGR-39 CTRP2 1.8169 3.2373 1.8151 28.1702
UACC-257 GDSC1; GDSC2; CTRP2 1.8283 3.463 1.8232 28.1053
WM793 GDSC1; GDSC2; CTRP2 1.8338 4.714 1.7323 28.3939
RVH-421 GDSC1; GDSC2; CTRP2 1.8644 2.7111 1.8644 27.8478
CJM [Human melanoma] CTRP2 1.896 2.6481 1.896 27.6373
MeWo GDSC1; GDSC2; CTRP2 1.9408 3.2677 1.9395 27.3431
WM1799 CTRP2 1.994 8.5242 0.7655 31.0068
WM983B CTRP2 2.021 4.4963 1.9594 27.0119
HMV-II GDSC1; GDSC2 2.0471 6.3507 0.6476 20.8125
SK-MEL-1 GDSC1; GDSC2; CTRP2 2.0745 3.098 2.0743 26.4489
K029AX CTRP2 2.2568 3.558 2.2548 25.2401
SK-MEL-2 GDSC1; GDSC2; CTRP2 2.5397 3.0159 2.5397 23.3486
Mel JuSo GDSC1; GDSC2; CTRP2 2.8487 4.4405 2.8314 21.3482
SK-MEL-31 GDSC2; CTRP2 2.9276 5.9862 2.6587 21.7015
Mel Ho GDSC1; GDSC2; CTRP2 3.6804 8.8719 2.3779 20.604
CP66-MEL GDSC1; GDSC2 3.9723 6.4059 2.2826 4.9122
SK-MEL-30 GDSC1; GDSC2; CTRP2 4.2908 6.8344 3.8689 13.2153
Hs 936.T CTRP2 9.3204 16.3491 3.2988 6.4691
EquiPSC Line K2 GDSC1; GDSC2 1.3465 3.8279 1.0094 21.631
⏷ Show the Full List of 74 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ESO-51 GDSC1; GDSC2 -7.874 1.229 -8.3953 79.5993
OACM5.1 C GDSC1; GDSC2 -2.0237 2.1047 -2.2303 53.1612
OACP4 C GDSC1; GDSC2 -1.2668 0.2397 -1.2685 46.0542
KYSE-50 GDSC1; GDSC2 -1.0873 0.4162 -1.0895 44.256
FLO-1 GDSC1; GDSC2 -0.6719 2.684 -0.8805 40.8564
SK-GT-4 GDSC1; GDSC2 -0.1843 1.5358 -0.2019 35.2724
KYAE-1 GDSC1; GDSC2 -0.1018 1.2072 -0.1056 34.3764
ESO-26 GDSC1; GDSC2 0.054 2.3408 -0.0324 33.2199
KYSE-220 GDSC1; GDSC2 0.3926 2.2851 0.337 29.6772
TE-12 GDSC1; GDSC2 0.5121 3.3623 0.2444 29.5569
HCE-4 GDSC1; GDSC2 2.6887 3.5414 2.5605 7.0504
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 2.0812 4.154 2.0534 26.4965
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NB(TU)1 GDSC1; GDSC2 -2.1337 1.2249 -2.2175 54.3912
NB69 GDSC1; GDSC2 -1.8729 0.4981 -1.8902 52.0885
GI-ME-N GDSC1; GDSC2 -1.6608 3.1774 -2.0771 50.0017
IMR-32 CTRP2 -1.5273 -0.9943 -1.5273 50.4436
TGW GDSC1; GDSC2 -1.4678 0.4238 -1.4744 48.0776
IMR-5 GDSC1; GDSC2 -1.2837 -0.1212 -1.2839 46.219
SJNB-7 GDSC1; GDSC2 -1.2573 0.6938 -1.2675 45.984
SJNB-14 GDSC1; GDSC2 -1.0814 0.3586 -1.083 44.1943
SJNB-13 GDSC1; GDSC2 -0.9503 1.1304 -0.9708 42.9523
SJNB-10 GDSC1; GDSC2 -0.8656 0.51 -0.8672 42.0295
SJNB-6 GDSC1; GDSC2 -0.8249 1.4603 -0.8628 41.7669
CHP-134 GDSC1; GDSC2 -0.6274 1.7853 -0.686 39.8841
SK-N-FI GDSC1; GDSC2; CTRP2 -0.6203 1.5053 -0.6223 44.4065
KP-N-YS GDSC1; GDSC2 -0.6043 0.993 -0.6108 39.4308
CHP-212 GDSC1; GDSC2; CTRP2 -0.538 0.8396 -0.5381 43.8533
NH-6 CTRP2 -0.4881 2.1992 -0.4998 43.5517
SK-N-MC-IXC GDSC1; GDSC2 -0.4578 1.292 -0.4715 37.9956
MHH-NB-11 GDSC1; GDSC2 -0.4464 2.4878 -0.5966 38.4615
SJNB-5 GDSC1; GDSC2 -0.3565 4.1122 -0.933 39.1032
SJNB-12 GDSC1; GDSC2 -0.3502 2.5141 -0.4975 37.5057
SK-N-SH GDSC1; GDSC2; CTRP2 -0.3393 2.9298 -0.3795 42.6339
Kelly GDSC1; GDSC2; CTRP2 -0.3224 0.5888 -0.3224 42.4164
NH-12 GDSC1; GDSC2 -0.2137 2.7013 -0.3866 36.2719
GOTO GDSC1; GDSC2 -0.0769 2.2653 -0.1614 34.5175
SiMa GDSC1; GDSC2; CTRP2 0.038 2.7313 0.0199 40.0706
SJNB-17 GDSC1; GDSC2 0.108 3.1064 -0.1291 33.3968
SK-N-DZ GDSC1; GDSC2; CTRP2 0.2347 2.5483 0.2263 38.7322
NB1 GDSC1; GDSC2; CTRP2 0.2571 1.5087 0.257 38.5563
SK-N-BE(2) CTRP2 0.4356 3.5555 0.382 37.5341
SK-N-AS GDSC1; GDSC2; CTRP2 0.6918 3.1616 0.6727 35.7222
LA-N-6 GDSC1; GDSC2 0.9716 3.785 0.6171 25.4536
KP-N-YN GDSC1; GDSC2; CTRP2 1.3457 4.0045 1.2969 31.4659
SK-N-BE(2)-M17 GDSC1; GDSC2 1.3766 3.0114 1.2749 20.0492
CHP-126 GDSC1; GDSC2; CTRP2 1.6758 3.932 1.647 29.2005
KP-N-RT-BM-1 GDSC2 2.0998 4.2202 1.6684 14.6674
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 -0.149 2.3796 -0.1595 41.2929
SNU-478 CTRP2 0.9753 3.5234 0.9463 33.8668
SNU-245 CTRP2 1.6554 4.7803 1.531 29.6581
HuCC-T1 GDSC1; GDSC2; CTRP2 1.6854 4.6891 1.5771 29.4043
SNU-1196 CTRP2 2.0207 4.0885 1.9949 26.8928
SNU-869 CTRP2 2.4405 4.7077 2.3796 24.2156
SNU-308 CTRP2 4.0677 8.2627 3.0432 17.0204
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFM-223 GDSC1; GDSC2 -0.7352 1.9518 -0.8208 41.053
HCC1187 GDSC1; GDSC2 -0.3442 2.9397 -0.5815 37.8078
CAL-148 GDSC1; GDSC2; CTRP2 -0.3002 1.093 -0.3003 42.2691
DU4475 GDSC1; GDSC2; CTRP2 0.0115 1.6531 0.011 40.1937
COLO 824 GDSC1; GDSC2 0.1979 2.8112 0.0373 32.1451
HCC1569 GDSC1; GDSC2 0.6605 2.3832 0.6096 26.9662
CAL-120 GDSC1; GDSC2; CTRP2 0.7353 2.7592 0.7296 35.3888
OCUB-M GDSC1; GDSC2 0.9382 3.9886 0.5122 26.1628
HCC1395 GDSC1; GDSC2; CTRP2 0.9564 3.3611 0.9357 33.9654
MDA-MB-468 GDSC1; GDSC2; CTRP2 1.0156 2.6426 1.014 33.5079
HCC1599 GDSC1; GDSC2 1.0182 4.0641 0.5721 25.4806
Evsa-T GDSC1; GDSC2 1.034 2.8219 0.9416 23.4355
EFM-19 GDSC1; GDSC2 1.0719 4.4545 0.4854 25.6979
HCC1806 GDSC1; GDSC2; CTRP2 1.1648 3.1593 1.1564 32.5364
HDQ-P1 GDSC1; GDSC2; CTRP2 1.1652 3.7719 1.127 32.6329
MDA-MB-157 GDSC1; GDSC2; CTRP2 1.2413 3.6728 1.2129 32.0933
Hs 578T GDSC1; GDSC2; CTRP2 1.2677 2.041 1.2677 31.8229
HCC38 GDSC1; GDSC2; CTRP2 1.3678 4.8083 1.2173 31.6554
CAL-51 GDSC1; GDSC2; CTRP2 1.4036 4.051 1.3535 31.0846
HCC1143 GDSC2; CTRP2 1.5216 3.578 1.5068 30.1809
CAL-85-1 GDSC1; GDSC2; CTRP2 1.5431 3.6132 1.5274 30.0407
HMC-1-8 CTRP2 1.6382 6.5245 1.0965 31.1434
Hs 578Bst CTRP2 1.7429 3.9834 1.7133 28.756
JIMT-1 GDSC1; GDSC2; CTRP2 2.0867 3.7725 2.078 26.3958
HCC1937 GDSC1; GDSC2; CTRP2 2.1133 4.0864 2.091 26.2644
MRK-nu-1 GDSC1; GDSC2 2.1268 6.096 0.8459 19.3959
MDA-MB-415 GDSC1; GDSC2; CTRP2 2.2012 3.3099 2.2007 25.6057
MDA-MB-361 GDSC1; GDSC2; CTRP2 2.2098 4.2886 2.1775 30.3512
AU565 GDSC1; GDSC2; CTRP2 2.2138 4.3213 2.1791 25.6368
YMB-1-E GDSC1; GDSC2 2.2453 3.5923 2.0635 11.7837
HCC1500 GDSC1; CTRP2 2.2557 3.2148 2.2555 25.2415
BT-20 GDSC1; GDSC2; CTRP2 2.337 4.4154 2.3001 24.8233
MDA-MB-453 GDSC1; GDSC2; CTRP2 2.3578 3.9032 2.3504 24.5856
KPL-1 CTRP2 2.368 2.7763 2.368 24.4924
ZR-75-30 GDSC1; GDSC2; CTRP2 2.4512 4.8779 2.369 24.217
SK-BR-3 CTRP2 2.4596 3.8827 2.4545 23.8995
T-47D GDSC1; GDSC2; CTRP2 2.4929 5.2246 2.3577 24.1223
BT-549 GDSC1; GDSC2; CTRP2 2.4965 4.1912 2.4811 23.6882
MDA-MB-330 GDSC1; GDSC2 2.5871 5.1302 1.7506 12.3098
HCC1954 GDSC1; GDSC2; CTRP2 2.5997 3.7966 2.5978 22.9553
MDA-MB-231 GDSC1; GDSC2; CTRP2 2.6345 4.9153 2.5596 22.9711
UACC-812 GDSC1; GDSC2; CTRP2 2.6932 4.8386 2.6321 22.5328
MCF-7 GDSC1; GDSC2 2.8892 4.1594 2.5043 6.5898
HCC2157 GDSC1; GDSC2 2.9005 3.5752 2.7745 4.9256
MDA-MB-175-VII GDSC1; GDSC2 2.9235 3.8881 2.6637 5.4919
HCC1428 GDSC1; GDSC2; CTRP2 2.9804 3.6488 2.9804 20.4129
UACC-893 GDSC1; GDSC2 3.1281 4.8681 2.3819 6.5401
HCC70 GDSC1; GDSC2 3.236 8.7253 0.5483 17.3363
EFM-192A GDSC1; GDSC2 3.3955 7.7604 1.1637 13.3251
BT-474 GDSC1; GDSC2; CTRP2 3.5581 5.6495 3.4277 17.0133
ZR-75-1 CTRP2 3.5815 7.8353 2.72 19.5747
HCC202 GDSC1; CTRP2 4.1641 7.5948 3.4304 15.2528
MDA-MB-436 GDSC1; GDSC2 4.2878 8.3409 1.5648 8.5624
HCC1419 GDSC1; GDSC2; CTRP2 4.3306 5.7295 4.2497 11.6955
HCC2218 GDSC1; GDSC2 4.6078 8.5716 1.6759 7.1875
BT-483 GDSC1; GDSC2 5.1798 8.1677 2.2161 3.0983
CAMA-1 GDSC1; GDSC2; CTRP2 6.0633 14.015 2.0749 16.2727
BT 416 CTRP2 -0.7295 7.7812 -1.8861 46.3604
BT 440 CTRP2 -0.1929 3.3025 -0.2548 41.7193
BT 231 CTRP2 0.4797 4.2153 0.3555 37.4505
BT 271 CTRP2 0.6702 3.9208 0.5939 36.0463
BT 286 CTRP2 0.765 3.4332 0.7339 35.2737
BT 145 CTRP2 1.038 3.4453 1.0156 33.4276
BT 428 CTRP2 1.088 6.9739 0.3557 35.2123
BT 112 CTRP2 1.1042 3.1549 1.0949 32.9433
BT 131 CTRP2 1.1941 3.8878 1.1481 32.4658
BT 187 CTRP2 1.2819 3.8198 1.2451 31.8512
BT 239 CTRP2 1.3331 3.5165 1.3159 31.4449
BT 330 CTRP2 1.3347 3.818 1.3002 31.4915
BT 139 CTRP2 1.5168 3.3824 1.5087 30.1905
BT 228 CTRP2 1.5388 3.6764 1.52 30.0797
BT164 CTRP2 1.5632 3.3283 1.5571 29.8748
BT 245 CTRP2 1.6918 4.4531 1.6155 29.2538
BT 172 CTRP2 1.7645 4.1552 1.7228 28.6531
BT 482 CTRP2 1.8762 3.6399 1.8673 27.7986
BT 159 CTRP2 2.0724 3.4285 2.0704 26.4687
BT 248 CTRP2 2.1267 4.6901 2.0482 26.3656
BT147 CTRP2 2.1599 4.6626 2.0871 26.1251
BT 328 CTRP2 2.247 2.9642 2.247 25.299
BT 232 CTRP2 2.3383 4.5061 2.2933 24.8421
BT 422 CTRP2 2.3418 4.6159 2.2855 24.8574
BT 224 CTRP2 2.3466 2.9111 2.3466 24.6354
BT 216 CTRP2 2.4072 3.2803 2.4071 24.2321
BT 179 CTRP2 2.4162 2.8193 2.4162 24.1713
BT 340 CTRP2 2.4393 2.9573 2.4393 24.0175
BT 359 CTRP2 2.4917 3.084 2.4917 23.6683
BT 333 CTRP2 2.6005 2.9413 2.6005 22.944
BT 320 CTRP2 4.4206 4.936 4.4201 10.8197
BT 498 CTRP2 9.1616 27.333 -2.1268 22.9449
BT 444 CTRP2 9.9921 23.0312 0.5733 14.8136
⏷ Show the Full List of 90 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 1.9554 4.0957 1.9265 27.3384
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GI-1 GDSC1 -1.9922 1.4549 -2.1771 53.7189
DK-MG GDSC1; GDSC2; CTRP2 -1.6437 3.3161 -1.7887 51.1345
KINGS-1 GDSC1; GDSC2 -1.6058 4.2088 -2.3218 49.5956
H4 GDSC1; GDSC2 -1.4923 0.1704 -1.4949 48.3161
D-247MG GDSC1; GDSC2 -1.427 2.4781 -1.6571 47.9241
YH-13 GDSC1; GDSC2; CTRP2 -1.1355 2.3662 -1.1703 47.8721
42-MG-BA GDSC1; GDSC2; CTRP2 -1.066 3.1951 -1.1627 47.4785
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 -1.0642 1.0201 -1.0827 44.0822
D-336MG GDSC1; GDSC2 -0.9878 0.9895 -1.0026 43.3062
KNS-60 CTRP2 -0.9388 0.4552 -0.9388 46.5231
MOG-G-UVW GDSC1; GDSC2 -0.9086 1.3446 -0.9412 42.5806
SF539 GDSC1; GDSC2; CTRP2 -0.7582 1.702 -0.7634 45.3324
MOG-G-CCM GDSC1; GDSC2 -0.7506 0.8215 -0.7554 40.8906
D-566MG GDSC1; GDSC2 -0.6846 1.4712 -0.7171 40.3474
T98G GDSC1; GDSC2; CTRP2 -0.4414 1.8942 -0.4462 43.223
M059J GDSC1; GDSC2 -0.4274 0.8589 -0.4293 37.6342
Onda 11 GDSC1; GDSC2 -0.4267 1.7353 -0.4693 37.816
AM-38 GDSC1; GDSC2 -0.3844 1.7865 -0.4298 37.4064
Becker GDSC1; GDSC2; CTRP2 -0.2632 4.1813 -0.4346 42.4239
D-423MG GDSC1; GDSC2 -0.219 2.9317 -0.4432 36.5403
D-502MG GDSC1; GDSC2 -0.1876 3.7886 -0.645 37.1525
SW1088 GDSC1; GDSC2; CTRP2 -0.1622 2.8541 -0.1917 41.433
8-MG-BA GDSC1; GDSC2; CTRP2 -0.0926 1.2361 -0.0926 40.8855
A-172 GDSC1; GDSC2; CTRP2 0.0071 2.4598 -0.0028 40.2519
U-118MG GDSC1; GDSC2; CTRP2 0.0687 3.5931 -0.0068 40.027
CAS-1 GDSC1; GDSC2; CTRP2 0.0873 1.5322 0.0871 39.6878
D-245MG GDSC2 0.1944 3.4109 -0.1159 32.8873
SF295 GDSC1; GDSC2; CTRP2 0.3254 3.9374 0.227 38.3953
KNS-81 CTRP2 0.3633 3.8716 0.2748 38.1162
Hs 683 GDSC1; GDSC2; CTRP2 0.4701 2.7726 0.4599 37.1697
D-392MG GDSC1; GDSC2 0.4942 2.3323 0.4391 28.6558
GaMG GDSC1; GDSC2; CTRP2 0.5408 2.0012 0.5404 36.6671
D-542MG GDSC1; GDSC2 0.565 2.2572 0.5232 27.8783
YKG-1 GDSC1; GDSC2; CTRP2 0.5758 3.3477 0.5431 36.5378
Daoy GDSC1; GDSC2; CTRP2 0.6027 2.7471 0.5953 36.2778
D-263MG GDSC1; GDSC2 0.7466 1.8009 0.7422 25.8656
SK-MG-1 GDSC1; GDSC2 0.7531 4.1292 0.2629 28.3087
KNS-81-FD GDSC1; GDSC2 0.8432 3.2432 0.6379 25.9411
LN-18 GDSC1; GDSC2; CTRP2 0.8675 3.0638 0.8563 34.5265
LNZTA3WT4 GDSC1 0.8852 2.2803 0.7709 19.1334
SNB-75 GDSC1; GDSC2; CTRP2 0.9482 2.6975 0.9455 33.9607
D283 Med GDSC1; GDSC2; CTRP2 0.9965 3.6864 0.9574 33.7587
KG-1-C CTRP2 1.0325 3.6934 0.9945 33.5154
SF268 GDSC1; GDSC2; CTRP2 1.0581 4.1754 0.9761 33.4884
SNU-738 CTRP2 1.0853 3.198 1.0743 33.0749
PFSK-1 GDSC1; GDSC2 1.1332 4.4417 0.5557 25.0519
SW1783 GDSC1; GDSC2; CTRP2 1.2215 4.4626 1.1134 32.4878
NMC-G1 GDSC1; GDSC2; CTRP2 1.2473 4.3545 1.1552 32.2641
CCF-STTG1 CTRP2 1.2706 5.1721 1.0443 32.5446
KNS-42 GDSC1; GDSC2; CTRP2 1.3147 3.2029 1.3077 31.5334
LN-405 GDSC1; GDSC2 1.3323 4.3807 0.7915 22.8981
GOS-3 CTRP2 1.4213 4.0438 1.3727 30.9618
SNU-201 CTRP2 1.4577 3.547 1.4425 30.6081
SF126 GDSC1; GDSC2; CTRP2 1.5466 3.4923 1.5357 30.0014
M059K CTRP2 1.5804 3.0365 1.5788 29.745
ONS-76 GDSC1; GDSC2; CTRP2 1.6432 3.5722 1.6316 29.3604
GB-1 GDSC1; GDSC2; CTRP2 1.6845 3.9058 1.6578 29.1355
SNU-1105 CTRP2 1.7254 4.2737 1.6707 28.9572
U-251MG GDSC1; GDSC2; CTRP2 1.7276 4.0605 1.6918 28.8788
GMS-10 CTRP2 1.8235 3.7247 1.8104 28.164
SNU-626 CTRP2 1.8238 3.7114 1.8113 28.1601
KALS-1 GDSC1; GDSC2; CTRP2 1.8628 4.1229 1.8281 27.9746
LN-229 GDSC1; GDSC2; CTRP2 2.0477 3.5471 2.0438 26.6396
SNU-489 CTRP2 2.0727 3.0296 2.0726 26.4604
TM-31 CTRP2 2.1044 3.647 2.0993 26.2658
DBTRG-05MG GDSC1; GDSC2; CTRP2 3.1539 8.5601 1.9703 23.5507
Onda 10 GDSC1; GDSC2 4.6289 8.7731 1.5937 7.6273
U-87MG ATCC GDSC1; GDSC2; CTRP2 7.8196 19.6207 0.673 17.8367
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1; GDSC2 -0.3074 1.2125 -0.3147 36.4566
ETK-1 GDSC1; GDSC2 -0.0614 2.9066 -0.2659 34.9134
TGBC1TKB GDSC1; GDSC2 0.6407 2.0857 0.6187 27.0178
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-2 CTRP2 -2.557 -0.0874 -2.5596 54.2391
MFE-280 GDSC1; GDSC2 -1.3178 0.9153 -1.3387 46.6118
AN3-CA GDSC1; GDSC2; CTRP2 -0.9746 2.4619 -1.0094 46.8152
JHUEM-7 CTRP2 -0.5133 2.6006 -0.5407 43.7557
EN GDSC1; GDSC2; CTRP2 0.5856 4.1719 0.4743 36.7132
RL95-2 GDSC1; GDSC2; CTRP2 0.7054 5.3379 0.3944 36.501
MFE-296 GDSC1; GDSC2; CTRP2 0.9211 4.0732 0.8426 34.3875
JHUEM-3 CTRP2 1.2839 2.9261 1.2814 31.7235
KLE GDSC1; GDSC2; CTRP2 1.3761 4.6798 1.247 31.5297
ESS-1 GDSC1; GDSC2; CTRP2 1.9896 3.162 1.989 27.0156
HEC-1-A CTRP2 2.0902 4.1733 2.0613 26.4403
JHUEM-1 CTRP2 2.1557 3.6554 2.1512 25.922
MFE-319 GDSC1; GDSC2; CTRP2 2.1591 3.4341 2.1577 25.889
EFE-184 CTRP2 2.8456 3.956 2.8438 21.3167
HEC-151 CTRP2 2.935 4.059 2.9327 20.7229
HEC-1-B CTRP2 3.0255 8.7809 1.7431 24.7234
HEC-50B CTRP2 3.0774 5.7498 2.8819 20.4434
HEC-59 CTRP2 4.5859 9.9647 2.7671 16.8115
HEC-265 CTRP2 7.5155 8.4947 5.7274 0.1074
HEC-108 CTRP2 7.6246 14.2352 3.1795 9.2325
HEC-6 CTRP2 7.646 11.726 4.4017 4.3546
HEC-251 CTRP2 8.7106 15.3483 3.3824 6.9105
Ishikawa (Heraklio) 02 ER- CTRP2 6.3896 7.4022 5.6272 1.1887
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LB1047-RCC GDSC1; GDSC2 -1.0078 0.3944 -1.0092 43.4554
RXF 393L GDSC1; GDSC2 -0.9496 0.9405 -0.9615 42.9135
KTCTL-21 GDSC1; GDSC2 -0.8313 2.339 -0.985 42.214
HA7-RCC GDSC1; GDSC2 -0.6314 1.0149 -0.639 39.7079
TUHR14TKB CTRP2 -0.5687 7.2197 -1.5247 69.3879
A-704 GDSC1; GDSC2 -0.5128 1.1399 -0.522 38.5259
NCC021 GDSC1; GDSC2 -0.4903 1.9133 -0.5554 38.5485
KTCTL-26A GDSC1; GDSC2 -0.3297 1.158 -0.3358 36.6745
KTCTL-1M GDSC1; GDSC2 -0.2058 1.1917 -0.2107 35.4253
KTCTL-140 GDSC1; GDSC2 -0.096 1.3536 -0.1034 34.336
BB65-RCC GDSC1; GDSC2 0.2901 1.3876 0.2878 30.4367
ACHN GDSC1; GDSC2; CTRP2 0.303 2.315 0.2995 38.2613
KTCTL-195 GDSC1; GDSC2 0.4109 2.3245 0.3514 29.5133
UO-31 GDSC1; GDSC2; CTRP2 0.4335 2.8777 0.4193 37.4264
SW156 GDSC1; GDSC2 0.4905 2.5543 0.4026 28.8604
CAL-54 GDSC1; GDSC2; CTRP2 0.5137 2.4743 0.5101 36.858
KTCTL-13 GDSC1; GDSC2 0.5189 1.6318 0.515 28.1482
LB996-RCC GDSC1; GDSC2 0.7278 2.6339 0.6447 26.4576
NCC010 GDSC2 0.8136 2.2925 0.782 25.3318
KMRC-20 GDSC1; GDSC2; CTRP2 1.0772 2.7364 1.0751 33.0991
LB2241-RCC GDSC1; GDSC2 1.1674 3.1402 1.0177 22.4015
Caki-1 GDSC1; GDSC2; CTRP2 1.3267 3.4054 1.3139 31.4726
786-O GDSC1; GDSC2; CTRP2 1.4181 3.3075 1.4102 30.8476
VMRC-RCW GDSC1; GDSC2; CTRP2 1.5723 4.2559 1.5111 29.9987
BFTC-909 GDSC1; GDSC2; CTRP2 1.5796 2.7598 1.5794 29.7458
KMRC-3 CTRP2 1.6596 2.7066 1.6595 29.2123
SW13 GDSC1; GDSC2 1.7381 2.5218 1.7298 15.9357
RCC10RGB GDSC1; GDSC2; CTRP2 1.7427 4.0263 1.7101 28.7676
KMRC-1 GDSC1; GDSC2; CTRP2 1.7731 2.2016 1.7731 28.4557
VMRC-RCZ GDSC1; GDSC2; CTRP2 1.9477 2.7 1.9477 27.2925
KMRC-2 CTRP2 1.9864 3.1267 1.986 27.0365
SN12C GDSC1; GDSC2 2.0727 4.9137 1.3409 16.7051
769-P GDSC1; GDSC2; CTRP2 2.1075 3.2548 2.107 26.2298
TUHR4TKB CTRP2 2.1319 3.2174 2.1316 26.0666
TUHR10TKB CTRP2 2.4421 3.1852 2.4421 23.9992
Caki-2 CTRP2 2.4436 2.8556 2.4436 23.9888
A-498 GDSC1; GDSC2; CTRP2 2.5837 3.4941 2.5835 23.0562
TK-10 GDSC1; GDSC2 2.7834 6.7236 1.1538 15.284
OS-RC-2 GDSC1; GDSC2; CTRP2 3.246 8.4518 2.112 22.7775
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 58 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H716 GDSC1; GDSC2; CTRP2 -3.3409 1.0181 -3.3756 61.8882
KM12 GDSC1; GDSC2; CTRP2 -2.7571 6.7694 -3.7683 56.0147
SNU-175 GDSC1; GDSC2; CTRP2 -1.5487 0.744 -1.5501 50.5851
SNU-1033 CTRP2 -1.2055 10.0013 -3.2145 48.935
SW48 GDSC1; GDSC2; CTRP2 -1.1862 0.4889 -1.1863 48.1714
GP2d CTRP2 -0.7102 2.6766 -0.7483 45.0793
SNU-407 GDSC1; CTRP2 -0.039 3.3726 -0.0995 40.699
SW620 GDSC1; GDSC2; CTRP2 0.0241 3.9259 -0.0917 40.4254
LS411N GDSC1; GDSC2; CTRP2 0.034 1.6714 0.0336 40.0435
COLO205 GDSC1; GDSC2; CTRP2 0.1567 1.4532 0.1566 39.225
GP5d GDSC1; GDSC2 0.2109 2.8107 0.0515 32.01
SW837 GDSC1; GDSC2 0.2727 3.3165 -0.0043 31.9641
LS513 GDSC1; CTRP2 0.4268 1.8467 0.4266 37.4258
SK-CO-1 GDSC2; CTRP2 0.474 2.8466 0.4616 37.1509
COLO 320 CTRP2 0.5197 3.6468 0.4622 36.9877
COLO 320HSR GDSC1; GDSC2 0.5328 3.1528 0.3225 29.0615
HCT 15 GDSC1; GDSC2; CTRP2 0.594 3.2215 0.5692 36.3918
SW948 GDSC1; GDSC2; CTRP2 0.5993 2.822 0.59 36.3065
DiFi GDSC2 0.6024 4.9705 -0.216 31.302
SNU-C2A CTRP2 0.6146 4.7691 0.4118 36.7885
NCI-H747 GDSC1; GDSC2; CTRP2 0.6182 3.2527 0.5926 36.2331
SNU-1040 GDSC1 0.6383 2.7577 0.3581 23.333
RKO GDSC1; GDSC2; CTRP2 0.6496 3.7735 0.587 36.1408
T84 GDSC1; GDSC2; CTRP2 0.7055 3.1699 0.6865 35.6306
HT115 GDSC1; GDSC2; CTRP2 0.728 3.3823 0.6988 35.5138
CL-11 GDSC1; GDSC2; CTRP2 0.7424 3.4151 0.7117 35.4228
CaR-1 GDSC1; GDSC2 0.9075 2.6576 0.8341 24.6055
LoVo GDSC1; GDSC2; CTRP2 0.9326 5.03 0.7063 34.7708
MDST8 GDSC1; CTRP2 0.9482 4.6329 0.7949 34.4437
SNU-503 CTRP2 0.9658 3.3659 0.9451 33.9029
SW1417 GDSC1; GDSC2; CTRP2 0.9745 3.4418 0.9501 33.857
SNU-C5 GDSC1; GDSC2; CTRP2 0.9941 3.8062 0.9456 33.8052
CCK-81 GDSC1; GDSC2 1.0088 3.1177 0.8503 24.0373
C2BBe1 GDSC1; GDSC2; CTRP2 1.0314 3.4715 1.0073 33.4769
SNU-61 GDSC1; CTRP2 1.0842 4.6579 0.937 33.5247
SNU-283 GDSC2 1.3696 4.998 0.58 23.8939
COLO 678 GDSC1; GDSC2; CTRP2 1.456 4.1091 1.4032 30.7448
NCI-H508 GDSC2; CTRP2 1.4836 3.7528 1.4589 30.4673
HCC-56 CTRP2 1.4873 3.4308 1.4771 30.394
SW626 GDSC1; GDSC2 1.4921 6.1539 0.1934 25.4054
SW1116 GDSC1; GDSC2; CTRP2 1.5281 3.5098 1.5161 30.1284
HT-55 GDSC1; GDSC2; CTRP2 1.6598 3.5885 1.6479 29.2505
HCC2998 GDSC1; GDSC2 1.6756 3.6851 1.4144 17.9239
LS1034 GDSC1; GDSC2; CTRP2 1.7891 3.0175 1.7885 28.3515
SNU-C1 GDSC1; GDSC2; CTRP2 1.7948 2.96 1.7944 28.3127
DLD-1 CTRP2 1.9744 3.4605 1.9711 27.126
LS123 GDSC1; GDSC2; CTRP2 1.9791 5.1102 1.8235 27.6114
SNU-81 GDSC1; GDSC2; CTRP2 2.0271 2.7516 2.0271 26.7638
SW1463 GDSC1; GDSC2 2.0748 3.8487 1.7879 14.0812
OUMS-23 CTRP2 2.1922 2.883 2.1922 25.6637
HCT 8 CTRP2 2.2538 3.1327 2.2537 25.2539
SNU-C2B GDSC1; GDSC2 2.2961 6.1757 0.9705 18.054
SNU-C4 CTRP2 2.4363 2.9735 2.4363 24.0376
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2 2.4442 4.6738 2.3874 24.1771
CW-2 GDSC1; GDSC2; CTRP2 2.5957 6.3939 2.1798 24.4297
LS180 GDSC1; GDSC2; CTRP2 4.6805 9.6053 3.03 15.5407
HT-29 GDSC1; GDSC2; CTRP2 6.1074 6.9908 5.6226 1.655
HCT 116 GDSC1; GDSC2; CTRP2 7.0158 8.655 5.4322 1.1956
⏷ Show the Full List of 58 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 1.8026 3.0563 1.7281 15.6323
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Li-7 CTRP2 -1.195 3.46 -1.3297 48.3299
SNU-475 GDSC1; CTRP2 -0.966 0.3236 -0.9661 46.7046
HuH-6 CTRP2 -0.9264 4.0284 -1.1226 46.6892
SNU-182 CTRP2 -0.8077 2.9956 -0.8725 45.7646
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 -0.7849 1.279 -0.7862 45.5008
JHH-4 GDSC1; GDSC2; CTRP2 -0.5482 2.6756 -0.5807 43.9983
SNU-387 GDSC1; GDSC2; CTRP2 -0.1069 3.2858 -0.1633 41.1372
JHH-7 GDSC1; GDSC2 -0.0742 1.1906 -0.0773 34.096
HLE GDSC1; GDSC2 0.0215 1.8035 -0.0057 33.2554
JHH-5 CTRP2 0.0654 2.9566 0.0377 39.9168
SNU-761 CTRP2 0.1946 1.7141 0.1943 38.9731
SNU-423 GDSC1; GDSC2; CTRP2 0.6622 2.8405 0.6536 35.8853
SNU-449 GDSC1; GDSC2; CTRP2 0.9728 2.544 0.9716 33.7916
SNU-878 CTRP2 1.0945 2.7179 1.0927 32.9828
Hep-G2 CTRP2 1.2252 2.8907 1.2226 32.1148
SNU-886 CTRP2 1.2544 5.2033 1.0202 32.6765
Huh-7 GDSC1; GDSC2 1.3075 3.274 1.1364 21.1131
JHH-2 GDSC1; GDSC2; CTRP2 1.5956 2.9636 1.5946 29.6416
JHH-6 GDSC1; GDSC2; CTRP2 1.6446 4.2173 1.5911 29.4914
Hep-G2/C3A GDSC1; GDSC2 1.8741 2.3598 1.8735 14.5321
SK-HEP-1 GDSC1; GDSC2; CTRP2 2.027 3.3646 2.0253 26.7702
JHH-1 GDSC1; GDSC2; CTRP2 2.1348 3.213 2.1344 26.0476
HLF CTRP2 2.1556 2.9433 2.1556 25.9076
SNU-398 GDSC1; GDSC2; CTRP2 2.3435 7.2335 1.628 27.138
HuH-1 GDSC1; GDSC2; CTRP2 2.3458 3.4319 2.3453 24.6424
PLC/PRF/5 CTRP2 2.5724 2.9742 2.5724 23.1308
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 220 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
EBC-1 GDSC1; GDSC2; CTRP2 -11.6683 -2.4603 -11.7889 88.628
SBC-3 GDSC1; GDSC2 -2.3074 -0.1648 -2.3135 56.4072
NCI-H847 GDSC1; GDSC2 -2.2699 -1.1293 -2.2699 56.1135
LC-2/ad GDSC1; GDSC2 -2.0804 1.305 -2.1702 53.8903
Lu-135 GDSC1; GDSC2 -1.9508 -0.3751 -1.9517 52.9065
NCI-H1703 GDSC1; GDSC2; CTRP2 -1.8968 6.5022 -2.7513 52.1889
NCI-H2227 GDSC1; GDSC2 -1.7719 0.1243 -1.7766 51.11
RERF-LC-MS GDSC1; GDSC2; CTRP2 -1.5169 2.4951 -1.5741 50.3626
NCI-H446 GDSC1; GDSC2; CTRP2 -1.3163 0.9998 -1.3183 49.0398
IST-SL1 GDSC1; GDSC2 -1.2723 0.745 -1.2845 46.1383
EMC-BAC-1 GDSC1; GDSC2 -1.2534 1.2247 -1.2917 46.013
NCI-H1048 GDSC1; GDSC2 -1.1563 0.7417 -1.1659 44.9726
COLO 699 CTRP2 -1.1476 3.9427 -1.3466 48.0716
DMS 273 GDSC1; GDSC2; CTRP2 -1.1309 2.0214 -1.1501 47.8265
NCI-H2171 GDSC1; GDSC2; CTRP2 -1.1018 0.0505 -1.1018 47.6092
NCI-H2795 GDSC1; GDSC2 -1.0544 1.6265 -1.1202 44.1265
NCI-H292 GDSC1; GDSC2; CTRP2 -0.9512 2.0153 -0.9663 46.6326
NCI-H2731 GDSC1; GDSC2 -0.8216 0.9138 -0.8299 41.6172
Lu-134-A GDSC1; GDSC2 -0.7453 1.9593 -0.8325 41.158
NCI-H1341 GDSC2; CTRP2 -0.7236 3.2033 -0.8029 45.2386
NCI-H647 GDSC1; GDSC2; CTRP2 -0.6911 1.2736 -0.692 44.8753
NCI-H835 GDSC2 -0.6882 2.9292 -0.9538 41.1905
LXF 289 GDSC1; GDSC2; CTRP2 -0.5753 0.896 -0.5754 44.1016
NCI-H1770 GDSC1; GDSC2 -0.5516 0.3315 -0.5517 38.872
NCI-H1184 CTRP2 -0.5355 1.8463 -0.5405 43.85
PC-14 GDSC1; GDSC2; CTRP2 -0.5045 0.9244 -0.5046 43.6299
Ms-1 GDSC1; GDSC2 -0.493 2.0187 -0.5715 38.631
HOP-62 GDSC1; GDSC2; CTRP2 -0.4874 2.1335 -0.4973 43.5422
NCI-H1876 GDSC1; GDSC2 -0.4703 1.6493 -0.5075 38.2279
HCC1588 CTRP2 -0.4685 3.2595 -0.54 43.5552
EMC-BAC-2 GDSC1; GDSC2 -0.3543 1.3432 -0.3675 36.9557
NCI-H2869 GDSC1; GDSC2 -0.291 2.1521 -0.3741 36.6443
SBC-5 GDSC1; GDSC2; CTRP2 -0.2905 3.2568 -0.3531 42.3648
COR-L303 GDSC1; GDSC2 -0.2761 1.4205 -0.2906 36.1778
NCI-H1755 GDSC1; GDSC2; CTRP2 -0.276 1.6659 -0.2774 42.1116
NCI-H810 GDSC1; GDSC2; CTRP2 -0.229 2.4943 -0.2446 41.8392
LK-2 GDSC1; GDSC2 -0.212 1.9024 -0.2597 35.6932
NCI-H1688 GDSC1; GDSC2 -0.1735 1.8278 -0.212 35.2645
NCI-H2081 GDSC1; GDSC2; CTRP2 -0.1521 1.7505 -0.1534 41.2859
VMRC-LCD GDSC2; CTRP2 -0.1465 2.4284 -0.1583 41.2799
UMC-11 GDSC1; GDSC2 -0.1306 2.6801 -0.2921 35.4033
NCI-H2228 GDSC1; GDSC2; CTRP2 -0.1237 1.8619 -0.1256 41.0989
NCI-H2085 GDSC1; GDSC2; CTRP2 -0.1095 2.2508 -0.1164 41.0194
NCI-H1155 GDSC1; GDSC2; CTRP2 -0.1062 2.6994 -0.1267 41.0364
HCC44 GDSC1; GDSC2; CTRP2 -0.0986 1.8731 -0.1005 40.9316
NCI-H1581 GDSC1; GDSC2; CTRP2 -0.0669 3.9872 -0.1966 41.0556
Lu-65 GDSC1; GDSC2; CTRP2 -0.0652 2.4321 -0.0757 40.7349
CAL-12T GDSC1; GDSC2; CTRP2 -0.0604 2.4849 -0.0723 40.7071
COR-L51 CTRP2 -0.0578 2.5378 -0.0712 40.6945
DV-90 CTRP2 -0.0476 2.4995 -0.0596 40.6223
NCI-H524 GDSC1; GDSC2 -0.0369 1.6841 -0.0581 33.8119
NCI-H211 GDSC1; GDSC2; CTRP2 -0.0358 2.8852 -0.063 40.5873
COR-L279 GDSC2; CTRP2 0.0176 2.8455 -0.006 40.2224
NCI-H510A GDSC1; GDSC2 0.0213 1.6999 0.0013 33.2218
LCLC-97TM1 GDSC1; GDSC2; CTRP2 0.0248 3.3643 -0.032 40.2671
DMS 454 CTRP2 0.0458 3.6592 -0.0378 40.1999
NCI-H1436 GDSC1; GDSC2 0.0715 2.5075 -0.0408 33.1696
HCC78 GDSC1; GDSC2; CTRP2 0.0788 2.1835 0.075 39.7561
NCI-H526 GDSC1; GDSC2 0.1241 1.8557 0.0973 32.2242
DMS 114 GDSC1; GDSC2; CTRP2 0.1394 2.7762 0.122 39.3938
A-427 GDSC1; GDSC2 0.1395 1.9791 0.1029 32.1195
Lu-99A GDSC1; GDSC2 0.1896 2.4726 0.0924 31.9177
ABC-1 GDSC1; GDSC2 0.2025 3.1754 -0.0436 32.5087
NCI-H3122 GDSC1; GDSC2 0.2173 2.1914 0.1623 31.4311
NCI-H322M GDSC1; GDSC2 0.22 1.8392 0.1984 31.2369
CPC-N GDSC1; GDSC2 0.2407 2.8082 0.0844 31.6985
COR-L321 GDSC1; GDSC2 0.2449 1.6992 0.2324 30.9409
NCI-H1944 GDSC1; GDSC2; CTRP2 0.2682 2.9591 0.2465 38.5501
NCI-H727 GDSC1; GDSC2 0.2731 2.7455 0.1325 31.2987
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2 0.2994 2.7799 0.2856 38.318
NCI-H838 GDSC1; GDSC2; CTRP2 0.3035 2.061 0.3023 38.2509
HCC15 GDSC1; GDSC2; CTRP2 0.311 2.2854 0.3079 38.2068
NCI-H2373 GDSC1; GDSC2 0.3231 2.8707 0.1605 30.9092
NCI-H2196 GDSC1; GDSC2; CTRP2 0.3298 3.1393 0.3008 38.1629
COR-L105 GDSC1; GDSC2; CTRP2 0.3302 3.5926 0.2682 38.2588
NCI-H358 GDSC1; GDSC2; CTRP2 0.3311 3.6445 0.2643 38.2666
EPLC-272H GDSC1; GDSC2; CTRP2 0.3469 3.4641 0.2966 38.1133
NCI-H2595 GDSC1; GDSC2 0.3493 5.4346 -0.6704 34.4009
NCI-H1648 GDSC1; GDSC2 0.3715 2.369 0.3033 29.9521
NCI-H596 GDSC1; GDSC2 0.3891 2.8334 0.2402 30.1833
NCI-H2135 GDSC1; GDSC2 0.3947 4.8432 -0.3868 33.0538
NCI-H841 GDSC1; GDSC2; CTRP2 0.4048 2.689 0.3957 37.6013
LB647-SCLC GDSC2 0.4394 4.6446 -0.2631 32.3044
NCI-H2591 GDSC1; GDSC2 0.4719 2.7768 0.3416 29.2624
NCI-H2810 GDSC2 0.4856 1.8657 0.472 28.5314
NCI-H1437 GDSC1; GDSC2 0.4972 2.4758 0.4222 28.7271
NCI-H209 GDSC1; GDSC2; CTRP2 0.5633 3.8201 0.4916 36.7416
NCI-H2141 GDSC1; GDSC2; CTRP2 0.5721 2.5597 0.5678 36.4715
NCI-H2369 GDSC1; GDSC2 0.5802 1.3172 0.5801 27.514
COR-L311 GDSC1; GDSC2 0.5879 1.9926 0.5704 27.5243
HCC1833 CTRP2 0.6234 5.8451 0.1815 37.3785
NCI-H1993 GDSC1; GDSC2 0.6379 6.103 -0.6522 32.9356
SHP-77 GDSC1; GDSC2; CTRP2 0.6446 2.7354 0.6381 35.9954
NCI-H2009 GDSC1; GDSC2; CTRP2 0.647 3.0299 0.6321 36.0072
NCI-H187 GDSC1 0.696 1.9684 0.6336 21.1524
LOU-NH91 GDSC1; GDSC2; CTRP2 0.7035 2.6144 0.6997 35.5944
NCI-H2106 CTRP2 0.729 3.4879 0.6931 35.5287
NCI-H1693 GDSC1; GDSC2; CTRP2 0.736 5.4513 0.4018 36.3672
NCI-H520 GDSC1; GDSC2; CTRP2 0.7691 4.2413 0.6607 35.4899
NCI-H23 GDSC1; GDSC2; CTRP2 0.7932 2.9264 0.7846 35.0127
NCI-H1694 GDSC1; CTRP2 0.8121 3.7779 0.7573 35.0362
NCI-H1792 GDSC1; GDSC2; CTRP2 0.8184 2.7724 0.8134 34.8327
NCI-H2030 GDSC1; GDSC2; CTRP2 0.85 6.3886 0.0403 32.6961
NCI-H1734 GDSC1; GDSC2; CTRP2 0.8544 3.5114 0.8218 34.6833
NCI-H1650 GDSC1; GDSC2; CTRP2 0.8568 2.8747 0.8503 34.5819
NCI-H1563 GDSC1; GDSC2; CTRP2 0.8881 2.9349 0.8808 34.376
HOP-92 GDSC1; GDSC2; CTRP2 0.9219 3.6118 0.8852 40.4999
HCC2279 CTRP2 0.9456 3.5549 0.9136 34.0746
NCI-H64 GDSC1; GDSC2 0.9487 2.5831 0.8899 24.1163
NCI-H1304 GDSC1 0.9675 3.0198 0.619 19.7289
NCI-H2347 GDSC1; GDSC2 0.9768 7.3165 -0.8557 32.1701
NCI-H2087 GDSC1; GDSC2; CTRP2 0.9836 3.2995 0.9664 33.7727
COR-L32 GDSC2 1.0246 4.0947 0.5681 25.4728
COLO 668 GDSC1; GDSC2; CTRP2 1.0268 4.4407 0.9084 33.8131
NCI-H82 GDSC1; GDSC2 1.035 3.2348 0.8493 23.9197
NCI-H720 GDSC1; GDSC2 1.0497 2.3066 1.0286 22.909
Lu-99 CTRP2 1.0646 3.9641 1.0053 33.3714
HCC1438 CTRP2 1.07 2.8768 1.0661 33.153
HCC1195 CTRP2 1.0702 5.6094 0.7282 34.2186
COR-L95 GDSC1; CTRP2 1.0921 3.6367 1.0603 33.0982
Sq-1 CTRP2 1.1034 4.675 0.9548 33.402
NCI-H1573 GDSC1; GDSC2; CTRP2 1.1044 4.3419 1.0048 33.2379
NCI-H2803 GDSC1; GDSC2 1.1104 4.4355 0.5338 25.27
SW1271 GDSC1; GDSC2; CTRP2 1.1109 3.1754 1.1011 32.9005
NCI-H2804 GDSC1; GDSC2 1.155 2.9137 1.0548 22.2632
COR-L23 GDSC1; GDSC2 1.1552 3.1719 0.9965 22.5724
PaCa-3 GDSC1; GDSC2 1.1644 3.0661 1.0319 22.34
SK-LU-1 GDSC1; GDSC2; CTRP2 1.2425 3.3159 1.231 32.0291
NCI-H69 GDSC1; GDSC2 1.2449 2.6508 1.1969 21.0882
HCC827 GDSC1; GDSC2; CTRP2 1.2927 2.8061 1.2868 26.7994
Lu-139 GDSC1; GDSC2 1.2999 2.7443 1.2419 20.5888
A-549 GDSC1; GDSC2; CTRP2 1.3462 2.6754 1.3457 31.3018
DMS 53 GDSC1; GDSC2; CTRP2 1.3536 3.8934 1.3143 31.3816
HCC366 GDSC2; CTRP2 1.362 3.3292 1.3524 31.2267
HCC33 GDSC1; GDSC2 1.3717 4.3134 0.8595 22.3515
NCI-H1793 GDSC1; GDSC2; CTRP2 1.3808 3.3039 1.3723 31.0979
NCI-H196 GDSC1; GDSC2; CTRP2 1.4384 3.7077 1.4148 30.7647
NCI-H1975 GDSC1; GDSC2 1.4406 4.4217 0.8907 21.881
NCI-H1092 GDSC1; GDSC2; CTRP2 1.4608 3.8934 1.4261 30.6524
RERF-LC-KJ GDSC1; GDSC2 1.4687 3.4381 1.2666 19.6672
NCI-H1435 GDSC1; GDSC2; CTRP2 1.4745 4.2297 1.4106 30.6587
HCC1171 CTRP2 1.4824 5.5287 1.1965 31.3396
NCI-H2023 GDSC1; GDSC2; CTRP2 1.4975 5.5475 1.2085 31.2505
NCI-H1963 GDSC1 1.5113 2.6706 1.3326 11.7718
SK-MES-1 GDSC1; GDSC2; CTRP2 1.5166 3.3492 1.5093 30.1892
NCI-H2461 GDSC1; GDSC2 1.5536 4.7807 0.8633 21.5571
NCI-H2110 GDSC1; GDSC2; CTRP2 1.5762 3.8725 1.5476 29.8633
Lu-165 GDSC1; GDSC2 1.5838 5.2943 0.6733 22.4896
NCI-H1915 GDSC1; GDSC2; CTRP2 1.6012 3.7883 1.5785 29.6771
NCI-H748 GDSC1; GDSC2 1.6247 4.3847 1.1005 19.9167
NCI-H2342 GDSC1; GDSC2; CTRP2 1.6518 3.0812 1.6503 29.2692
NCI-H2066 GDSC2 1.6921 8.0934 -0.5286 27.9451
COR-L88 GDSC1; GDSC2; CTRP2 1.6957 4.5465 1.6079 29.2669
ChaGo-K-1 GDSC1; GDSC2; CTRP2 1.7001 4.3879 1.6319 29.1712
HCC2108 CTRP2 1.7004 7.3653 0.887 31.5907
NCI-H522 GDSC1; GDSC2; CTRP2 1.7291 5.1281 1.5498 29.3534
NCI-H1105 GDSC2; CTRP2 1.7383 3.247 1.7357 28.6964
HCC95 CTRP2 1.7458 2.6593 1.7457 28.6382
HCC4006 CTRP2 1.7538 3.2791 1.751 28.5939
EKVX GDSC1; GDSC2; CTRP2 1.7705 3.4152 1.7655 28.4899
NCI-H250 GDSC2 1.7961 8.1703 -0.4673 27.2843
RERF-LC-Sq1 GDSC1; GDSC2 1.8243 4.6209 1.2129 18.4451
NCI-H3255 GDSC1; GDSC2 1.8275 3.5498 1.6235 16.0865
NCI-H2126 CTRP2 1.8604 5.006 1.7141 28.3689
NCI-H661 GDSC1; GDSC2; CTRP2 1.8767 7.067 1.1808 30.0949
NCI-H1781 GDSC1; GDSC2 1.8821 2.4252 1.8807 14.4559
T3M-10 CTRP2 1.9005 2.7404 1.9005 27.6071
NCI-H2170 GDSC1; GDSC2; CTRP2 1.9031 3.7505 1.891 27.6301
NCI-H1666 GDSC1; GDSC2; CTRP2 1.9147 3.5425 1.9091 27.5316
NCI-H2029 GDSC1; GDSC2; CTRP2 1.9273 3.8101 1.9133 27.4754
LK2 CTRP2 1.94 2.7744 1.94 27.3439
NCI-H1836 GDSC1; GDSC2 1.9404 3.8586 1.6399 15.5001
NCI-H889 CTRP2 1.9566 5.0923 1.8025 27.7564
NCI-H146 GDSC2; CTRP2 1.9611 3.8469 1.9464 27.2527
LUDLU-1 CTRP2 1.962 3.266 1.9608 27.2018
NCI-H2405 GDSC1; GDSC2; CTRP2 1.9649 6.5717 1.4379 28.9676
NCI-H2818 GDSC1; GDSC2 1.9686 3.9145 1.6494 15.3255
Calu-3 GDSC1; GDSC2; CTRP2 1.9861 3.8118 1.9736 27.0787
LC-1/sq-SF CTRP2 2.0013 2.7297 2.0012 26.936
HCC2935 CTRP2 2.0077 3.514 2.0039 26.9056
NCI-H1869 GDSC1; GDSC2; CTRP2 2.0353 4.1902 2.0029 26.8178
NCI-H1623 GDSC1; GDSC2; CTRP2 2.0415 4.71 1.9548 26.961
NCI-H1568 GDSC1; GDSC2; CTRP2 2.0934 3.4312 2.0915 26.3286
RERF-LC-Ad2 CTRP2 2.149 4.0219 2.1315 26.0102
NCI-H2122 GDSC1; GDSC2; CTRP2 2.1523 3.7951 2.1442 25.9568
SBC-1 GDSC1; GDSC2 2.1677 4.3656 1.6785 14.3329
NCI-H1838 GDSC1; GDSC2; CTRP2 2.2217 3.2718 2.2214 25.4683
NCI-H226 GDSC1; GDSC2; CTRP2 2.2764 5.6756 2.0268 25.9606
NCI-H1651 GDSC1; GDSC2; CTRP2 2.3374 4.7497 2.2648 24.9422
NCI-H1373 CTRP2 2.3694 5.2784 2.2139 25.0149
RERF-LC-A1 CTRP2 2.373 3.8614 2.367 24.4794
NCI-H1339 CTRP2 2.3984 4.1089 2.3841 24.338
DMS 79 GDSC1; GDSC2; CTRP2 2.4055 4.9335 2.312 24.5603
NCI-H2444 GDSC1; GDSC2; CTRP2 2.4071 5.2036 2.2688 24.7044
LC-1/sq GDSC1; GDSC2 2.4148 4.2937 1.965 11.6534
NCI-H322 CTRP2 2.4215 3.8939 2.4155 24.1561
LCLC-103H GDSC1; GDSC2; CTRP2 2.4514 5.0305 2.3463 24.2943
SW1573 GDSC1; GDSC2; CTRP2 2.5785 6.2666 2.199 24.4142
Calu-6 GDSC1; GDSC2; CTRP2 2.6044 6.4139 2.1832 24.391
NCI-H1395 CTRP2 2.6553 5.2714 2.5245 23.0258
NCI-H1355 GDSC1; GDSC2; CTRP2 2.6698 5.1025 2.5694 22.824
IST-SL2 GDSC2 2.7046 4.7979 2.0225 10.2172
NCI-H290 GDSC2 2.8007 7.0107 1.027 15.9814
IA-LM GDSC1; GDSC2 2.9394 5.202 2.0467 9.2587
NCI-H441 GDSC1; GDSC2 2.9714 6.5087 1.4277 13.0115
NCI-H345 GDSC1; GDSC2 3.2283 6.0625 1.8729 9.4445
Calu-1 CTRP2 3.298 6.1468 3.0186 19.277
RERF-LC-Ad1 CTRP2 3.4067 9.1666 1.968 22.8597
NCI-H513 GDSC1; GDSC2 3.4539 5.885 2.1486 7.0529
NCI-H740 GDSC2 3.548 9.3433 0.4975 16.6862
KNS-62 GDSC2; CTRP2 3.6674 6.4209 3.3385 17.0026
NCI-H2722 GDSC1; GDSC2 3.6845 9.5196 0.5198 16.1752
NCI-H1299 GDSC1; GDSC2; CTRP2 4.0846 9.498 2.4997 19.0887
NCI-H2172 GDSC1; GDSC2 4.2953 9.8529 0.8279 12.8431
NCI-H650 GDSC1; GDSC2; CTRP2 4.4993 10.2781 2.5337 17.9328
NCI-H2291 GDSC1; GDSC2; CTRP2 4.6144 13.0001 1.3131 22.1168
MOR/CPR CTRP2 5.1865 6.8326 4.8176 7.0941
NCI-H460 GDSC1; GDSC2; CTRP2 6.4763 12.8832 2.9779 11.9826
BEN GDSC1; GDSC2; CTRP2 7.4565 8.5204 5.6958 0.17
Hs 888.Lu CTRP2 1.1224 5.8154 0.7337 34.0187
⏷ Show the Full List of 220 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 0.609 2.6267 0.518 27.6892
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 -8.6002 -7.9622 -8.6002 97.081
Yamato-SS CTRP2 -4.3372 1.1894 -4.417 66.962
A-204 GDSC1; GDSC2; CTRP2 -4.2467 2.4008 -4.4419 65.3766
Tm87-16 CTRP2 -2.4794 3.1972 -2.6634 56.0665
EW-8 GDSC1; GDSC2 -2.2631 -0.7517 -2.2635 56.0364
G-402 GDSC1; GDSC2; CTRP2 -2.1431 3.8856 -2.4075 53.9876
G-401 GDSC1; GDSC2; CTRP2 -1.503 1.1911 -1.5082 50.2804
Hs 633.T GDSC1; GDSC2 -1.0049 0.1706 -1.0052 43.4218
SW982 GDSC1; GDSC2; CTRP2 -0.6788 0.5496 -0.6788 44.7908
TE 441.T GDSC1; GDSC2; CTRP2 -0.1041 2.1298 -0.1089 40.9773
TTC-709 CTRP2 -0.0802 2.6179 -0.0968 40.8526
Rh41 GDSC1; GDSC2; CTRP2 -0.0137 1.6805 -0.0143 40.3621
VA-ES-BJ GDSC1; GDSC2 0.3211 1.9763 0.2936 30.2523
RD GDSC1; GDSC2; CTRP2 0.4209 2.6633 0.4127 37.491
SK-LMS-1 GDSC1; GDSC2; CTRP2 0.5464 3.1695 0.5227 36.7049
STS-0421 GDSC2 0.5554 2.2949 0.5087 27.9993
Rh18 CTRP2 0.6749 3.7489 0.6159 35.9615
KYM-1 GDSC1; GDSC2; CTRP2 0.7491 3.3564 0.7221 35.3663
Rh30 GDSC1; GDSC2 0.8524 2.446 0.8057 25.0198
SW872 GDSC1; GDSC2 0.931 2.0933 0.9196 24.0507
TE 617.T CTRP2 1.1354 3.6413 1.1049 32.8056
HT-1080 GDSC1; GDSC2; CTRP2 1.2331 2.3762 1.233 32.0536
MFH-ino GDSC1; GDSC2 1.2343 4.5097 0.6368 24.1703
GCT GDSC1; GDSC2; CTRP2 1.4817 3.3335 1.4742 30.4222
BT-12 CTRP2 1.5328 3.2479 1.528 30.0728
MES-SA GDSC1; GDSC2; CTRP2 1.5772 3.0098 1.5758 29.766
Hs 729.T CTRP2 1.7275 3.7515 1.7107 28.816
SK-UT-1 GDSC1; GDSC2; CTRP2 2.1068 4.3777 2.062 26.3834
SW684 GDSC1; GDSC2 2.9158 3.3074 2.8826 4.2499
RKN GDSC1; GDSC2; CTRP2 7.9848 12.3392 4.3296 4.2081
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 -3.3553 2.5327 -3.5113 61.0746
A2780 GDSC1; GDSC2; CTRP2 -1.7696 2.5603 -1.8429 51.9682
IGROV-1 GDSC1; GDSC2; CTRP2 -1.3736 3.6416 -1.5441 49.4615
JHOS-4 GDSC2 -0.4228 2.5715 -0.5871 38.2866
ES-2 GDSC1; GDSC2 -0.1575 1.6811 -0.1833 35.0432
Caov-3 GDSC1; GDSC2; CTRP2 -0.0355 3.1431 -0.0782 40.6284
JHOS-2 GDSC1; GDSC2; CTRP2 0.0917 3.3762 0.0369 39.8188
TOV-112D GDSC1; GDSC2; CTRP2 0.2736 3.1512 0.242 38.5441
Caov-4 GDSC1; GDSC2 0.3832 4.0236 -0.101 31.8591
OC 314 GDSC1; GDSC2; CTRP2 0.4488 2.4891 0.4443 37.2935
COV434 CTRP2 0.4683 3.7671 0.3968 37.3711
OVKATE GDSC1; GDSC2 0.553 4.5317 -0.099 31.0124
OV-90 GDSC1; GDSC2; CTRP2 0.882 2.4489 0.881 34.396
TOV-21G GDSC1; GDSC2; CTRP2 1.2795 2.7654 1.2783 31.7484
OAW28 GDSC1; GDSC2; CTRP2 1.3655 4.5199 1.2592 31.525
DOV13 GDSC1; GDSC2; CTRP2 1.3814 2.9869 1.3789 31.0737
RMG-I GDSC1; GDSC2; CTRP2 1.4133 3.6837 1.3901 30.9305
FU-OV-1 GDSC1; GDSC2; CTRP2 1.4733 5.7354 1.1367 31.564
OVTOKO GDSC1; GDSC2; CTRP2 1.5315 4.7299 1.4059 30.4857
OV7 CTRP2 1.6697 2.6632 1.6696 29.1451
OVCAR-5 GDSC1; GDSC2; CTRP2 1.7265 4.3243 1.6667 28.9671
COV644 CTRP2 1.8557 3.2601 1.8539 27.9114
OVISE GDSC1; GDSC2; CTRP2 1.915 3.6538 1.9064 27.5393
SNU-119 CTRP2 2.0085 3.5974 2.0031 26.9059
OAW42 GDSC1; GDSC2; CTRP2 2.0885 3.3839 2.087 26.3597
JHOM-1 CTRP2 2.1331 3.5319 2.1304 26.0666
COV362 CTRP2 2.1565 4.346 2.117 26.0344
OVK18 GDSC1; GDSC2; CTRP2 2.1724 3.1209 2.1723 25.796
MCAS CTRP2 2.2025 5.9075 1.8882 26.6762
SNU-8 CTRP2 2.2169 3.0255 2.2169 25.4995
ONCO-DG-1 CTRP2 2.2303 3.6503 2.2267 25.4221
SNU-840 CTRP2 2.3344 5.4481 2.1415 25.3777
SK-OV-3 GDSC1; GDSC2; CTRP2 2.4882 4.5602 2.4457 23.8348
Kuramochi GDSC1; GDSC2; CTRP2 2.5352 5.2286 2.4026 23.832
OVCAR-4 GDSC1; GDSC2; CTRP2 2.6254 6.4015 2.2098 24.232
EFO-27 GDSC1; GDSC2; CTRP2 2.6602 6.5799 2.1922 24.1894
TYK-nu GDSC1; GDSC2; CTRP2 2.7326 4.6533 2.694 22.1936
ES2 CTRP2 2.8612 4.5938 2.8338 21.2989
EFO-21 GDSC1; GDSC2; CTRP2 2.9065 5.2174 2.8051 21.2507
OVCAR-3 GDSC1; GDSC2 3.142 4.4593 2.5971 5.1405
OV56 GDSC1; GDSC2; CTRP2 3.9515 4.9319 3.9433 13.9707
HEY A8 CTRP2 3.9991 7.6268 3.2445 16.4203
OVCAR-8 GDSC1; GDSC2; CTRP2 4.242 9.2237 2.7829 17.5924
OVSAHO CTRP2 5.4153 9.7315 3.6535 11.3252
JHOC-5 CTRP2 5.7233 10.8906 3.3488 11.9358
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 0.8921 3.7386 0.8444 34.4815
P-STS CTRP2 1.8847 4.3478 1.8311 27.8926
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 2.4771 3.9625 2.4702 23.7889
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-Mes1 GDSC1; GDSC2; CTRP2 0.3347 2.3789 0.3307 38.0516
MPP 89 GDSC1; GDSC2; CTRP2 0.3931 2.1543 0.3917 37.6546
NCI-H28 GDSC1; GDSC2; CTRP2 1.2635 3.5744 1.2414 31.9244
MSTO-211H GDSC1; GDSC2; CTRP2 1.5559 3.5682 1.5424 29.948
NCI-H2452 GDSC1; GDSC2; CTRP2 1.681 4.1849 1.6325 29.2324
NCI-H2052 GDSC1; GDSC2; CTRP2 1.7848 4.4795 1.711 28.6265
JL-1 CTRP2 2.1589 4.1477 2.1345 25.9673
ACC-MESO-1 CTRP2 2.2022 3.0419 2.2022 25.5974
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1; GDSC2; CTRP2 0.8 2.6947 0.7961 34.952
PC-3 GDSC1; GDSC2 1.0367 4.565 0.4051 26.2766
22Rv1 GDSC1; GDSC2; CTRP2 1.468 5.0423 1.2837 31.1022
LNCaP clone FGC GDSC1; GDSC2; CTRP2 1.6031 5.9975 1.2102 30.8944
DU145 GDSC1; GDSC2; CTRP2 2.488 4.5372 2.4477 23.8288
NCI-H660 GDSC2 3.3275 4.6475 2.6638 4.1509
PaCa-3 CTRP2 4.278 6.8285 3.8574 13.295
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 1.1304 2.5413 1.1298 32.7398
A-253 GDSC1; GDSC2; CTRP2 1.8769 3.3044 1.8747 27.7718
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 -2.9015 -1.0883 -2.9024 62.3686
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-620 CTRP2 -6.7523 -5.3286 -6.7523 85.114
SNU-5 GDSC1; GDSC2; CTRP2 -4.9158 5.0554 -5.662 65.2256
Hs 746.T GDSC1; GDSC2; CTRP2 -3.5464 11.6715 -6.3582 56.8302
KATO III GDSC2; CTRP2 -3.0197 4.6919 -3.5138 58.1457
IM95 GDSC1; GDSC2; CTRP2 -2.4473 5.0322 -2.9674 55.2542
SNU-16 GDSC1; GDSC2; CTRP2 -2.4313 1.0613 -2.4466 56.3452
SNU-1 GDSC1; GDSC2; CTRP2 -0.9198 2.6773 -0.9656 46.4705
RERF-GC-1B GDSC1; GDSC2 -0.8069 2.0858 -0.9166 41.8387
HGC-27 GDSC1; GDSC2; CTRP2 -0.6675 0.543 -0.6675 44.7155
SK-GT-2 GDSC2 -0.5976 2.6865 -0.8003 40.1238
RF-48 GDSC1 -0.5591 2.4949 -0.8642 38.0098
Fu97 GDSC1; GDSC2; CTRP2 -0.5349 2.614 -0.5637 43.9022
LMSU CTRP2 -0.2739 3.1723 -0.3288 42.2371
MKN28 GDSC1; GDSC2 0.3026 3.1901 0.0619 31.4956
NUGC-4 GDSC1; GDSC2; CTRP2 0.3316 4.7003 0.1187 38.6648
ECC10 GDSC1; GDSC2; CTRP2 0.345 2.6968 0.3346 38.0038
MKN45 GDSC1; GDSC2; CTRP2 0.5817 38.3894 -14.8793 47.0821
SNU-216 CTRP2 0.8596 2.8024 0.8546 34.5585
NCI-N87 GDSC1; GDSC2; CTRP2 0.965 2.957 0.9584 33.8616
SNU-719 CTRP2 1.1329 3.728 1.0965 32.8416
OCUM-1 GDSC1; GDSC2; CTRP2 1.2377 3.9917 1.1846 32.1993
SCH GDSC1; GDSC2 1.2779 2.41 1.2587 20.6091
TMK-1 GDSC1; GDSC2 1.2802 3.0883 1.153 21.1513
HuG1-N CTRP2 1.4879 4.2287 1.4248 30.5671
GCIY GDSC1; GDSC2 1.5542 3.3217 1.3929 18.5889
MKN1 GDSC1; GDSC2; CTRP2 1.6298 3.4638 1.6214 29.4386
MKN7 GDSC1; GDSC2; CTRP2 1.6312 3.6659 1.6155 29.4538
GSS CTRP2 1.6649 3.263 1.6614 29.1886
MKN74 CTRP2 1.7692 5.0798 1.6023 29.0454
23132/87 GDSC1; GDSC2; CTRP2 1.8343 2.8834 1.8341 28.049
SNU-601 CTRP2 1.9546 3.2274 1.9536 27.2503
ECC12 GDSC2; CTRP2 1.9928 2.6777 1.9928 26.9925
GSU CTRP2 2.1225 2.6903 2.1225 26.128
SH-10-TC CTRP2 2.344 2.8802 2.344 24.6525
TGBC11TKB GDSC1; GDSC2 2.3888 3.8182 2.1353 10.759
KE-39 CTRP2 2.4581 6.8861 1.8722 25.9389
SNU-668 CTRP2 2.539 6.8408 1.9752 25.3297
HSC-39 GDSC1; GDSC2 2.8882 3.6943 2.7128 5.3369
NUGC-3 GDSC1; GDSC2; CTRP2 6.5101 12.4616 3.2151 10.9641
AGS GDSC1; GDSC2; CTRP2 7.1821 13.125 3.4017 9.0498
SNU-1077 CTRP2 1.6291 3.2703 1.625 29.4291
SNU-685 CTRP2 1.6696 2.708 1.6695 29.1458
SNG-M GDSC1; GDSC2; CTRP2 2.5642 4.5686 2.5249 23.3177
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW579 CTRP2 -3.1332 3.3111 -3.3793 59.4727
CGTH-W-1 GDSC1; GDSC2; CTRP2 -1.427 2.0161 -1.4534 49.7793
BHT-101 GDSC1; GDSC2 -0.7475 0.987 -0.7565 40.878
8505C GDSC1; GDSC2; CTRP2 0.1044 2.184 0.1008 39.5849
IHH-4 GDSC1; GDSC2 0.2158 0.8798 0.2158 31.1701
B-CPAP GDSC1; GDSC2; CTRP2 0.261 1.514 0.261 38.5298
K5 GDSC1; GDSC2 0.4487 2.5517 0.358 29.2935
ML-1 [Human leukemia] GDSC1; GDSC2; CTRP2 0.8321 3.5432 0.7965 34.8415
WRO GDSC1; GDSC2 0.8422 2.1344 0.8251 24.9702
HTC-C3 GDSC1; GDSC2 1.1334 3.5906 0.8551 23.4341
TT2609-C02 GDSC1; GDSC2; CTRP2 1.1741 3.4828 1.1539 32.5135
TT GDSC1; GDSC2; CTRP2 1.4945 3.1769 1.4905 30.3254
CAL-62 GDSC1; GDSC2; CTRP2 1.7619 2.6602 1.7619 28.5308
8305C GDSC1; GDSC2; CTRP2 1.7761 3.3816 1.7719 28.4499
FTC-238 CTRP2 2.0391 3.2588 2.0383 26.6868
KMH-2 GDSC1; GDSC2 2.682 3.5529 2.5492 7.1437
ASH-3 GDSC1; GDSC2 2.8737 3.4771 2.783 4.9904
FTC-133 GDSC1; GDSC2; CTRP2 4.8302 7.273 4.2594 10.2321
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 55 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PCI-06A GDSC1; GDSC2 -1.3939 1.4796 -1.4631 47.4405
NCI-H3118 GDSC1; GDSC2 -1.2795 0.7094 -1.2906 46.2073
KOSC-2 GDSC1; GDSC2 -1.2038 1.087 -1.2306 45.4949
BICR 18 CTRP2 -1.1218 3.0425 -1.2063 47.8273
BB30-HNC GDSC1; GDSC2 -1.0746 0.9145 -1.0886 44.1704
PCI-38 GDSC1 -0.9444 0.4448 -0.9512 41.2953
JHU-011 GDSC1; GDSC2 -0.7639 1.1379 -0.7792 41.0687
PCI-04B GDSC1; GDSC2 -0.6946 1.8086 -0.7597 40.5759
SCC-15 GDSC1; GDSC2 -0.4262 2.3399 -0.5484 38.1506
BICR 16 CTRP2 -0.4038 8.3199 -1.7231 44.8203
OSC-20 GDSC1; GDSC2 -0.3269 1.7815 -0.3688 36.8159
SAS GDSC1; GDSC2 -0.2814 2.0542 -0.3508 36.4869
OSC-19 GDSC1; GDSC2 -0.1712 1.4641 -0.1847 35.1203
DOK GDSC1; GDSC2 -0.1189 2.2852 -0.2093 34.9637
BB49-HNC GDSC1; GDSC2 -0.0906 1.9236 -0.1338 34.4573
CAL-33 GDSC1; GDSC2; CTRP2 -0.0236 1.8576 -0.0251 40.4308
HO-1-N-1 GDSC1; GDSC2 0.0257 1.3876 0.0196 33.1084
Detroit 562 GDSC1; GDSC2; CTRP2 0.0596 3.0119 0.0287 39.9646
LB771-HNC GDSC1; GDSC2 0.0823 2.682 -0.0617 33.2139
SAT [Human HNSCC] GDSC1; GDSC2 0.1905 2.481 0.0919 31.9156
CAL-27 GDSC1; GDSC2; CTRP2 0.2308 1.8886 0.2301 38.7334
Ca9-22 GDSC1; GDSC2 0.378 1.7557 0.3666 29.5997
SCC-25 GDSC1; GDSC2; CTRP2 0.5523 3.9382 0.4674 36.8546
BICR 31 GDSC1; GDSC2; CTRP2 0.56 1.7091 0.5599 36.5381
SKN-3 GDSC1; GDSC2 0.5658 2.3136 0.5176 27.9026
HO-1-u-1 GDSC1; GDSC2 0.6352 2.9557 0.4811 27.7522
JHU-022 GDSC1; GDSC2 0.7077 3.8983 0.2931 28.3704
YD-8 CTRP2 0.7775 1.9557 0.7774 35.0893
YD-10B CTRP2 0.7863 1.5077 0.7863 35.0302
BICR 10 GDSC1; GDSC2 0.857 1.8603 0.8528 24.7569
BICR 78 GDSC1; GDSC2 1.1078 3.3281 0.9038 23.2894
SNU-1076 CTRP2 1.1113 3.2974 1.0974 32.9112
KON GDSC1; GDSC2 1.1784 2.317 1.1621 21.5929
BICR 56 CTRP2 1.2619 5.1675 1.0357 32.6014
PE/CA-PJ49 CTRP2 1.2878 2.893 1.2857 31.6962
SNU-1214 CTRP2 1.3725 4.7966 1.2243 31.6167
HSC-2 GDSC1; GDSC2; CTRP2 1.4057 2.8069 1.4048 30.9066
JHU-029 GDSC2 1.466 3.5927 1.2166 19.954
SCC-4 GDSC1; GDSC2; CTRP2 1.5643 4.279 1.5003 30.0613
BICR 22 GDSC1; GDSC2; CTRP2 1.6944 3.093 1.693 28.985
BICR 6 CTRP2 1.7242 4.2435 1.6724 28.9556
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 1.7331 3.2238 1.7307 28.7304
FaDu GDSC1; GDSC2; CTRP2 1.8904 4.4735 1.8237 27.8989
BHY GDSC1; GDSC2; CTRP2 1.8909 3.3162 1.8887 27.6786
SCC-9 GDSC1; GDSC2; CTRP2 1.9236 4.0006 1.8997 27.5335
PE/CA-PJ34 (clone C12) CTRP2 2.1329 3.1983 2.1326 26.0601
PE/CA-PJ41 (clone D2) CTRP2 2.2631 3.1759 2.263 25.1918
SNU-1041 CTRP2 2.3098 6.5517 1.8197 26.579
HSC-4 GDSC1; GDSC2; CTRP2 2.3936 4.6214 2.3397 24.504
PCI-30 GDSC1; GDSC2 2.4729 6.0336 1.2067 16.0258
SNU-1066 CTRP2 2.8348 8.926 1.4831 26.1692
PCI-15A GDSC1; GDSC2 2.8506 4.4312 2.3382 7.7496
SNU-899 CTRP2 3.0642 8.4561 1.9205 23.9834
HSC-3 GDSC1; GDSC2; CTRP2 5.1938 10.3631 3.1408 13.9141
UPCI-SCC-090 GDSC2 5.4832 10.597 1.2891 7.6493
⏷ Show the Full List of 55 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RT-112 GDSC1; GDSC2; CTRP2 -0.9847 2.0603 -1.002 46.8575
RT-4 GDSC1; GDSC2 -0.9626 2.7824 -1.2184 43.7271
JMSU-1 CTRP2 -0.3361 1.8998 -0.3399 42.5192
BFTC-905 GDSC1; GDSC2; CTRP2 0.2557 1.87 0.2552 38.5669
UM-UC-1 CTRP2 0.2694 2.9398 0.2486 38.5392
5637 GDSC1; GDSC2; CTRP2 0.3252 2.0326 0.3242 38.1052
639V GDSC1; GDSC2; CTRP2 0.39 1.6343 0.3899 37.6709
SW780 GDSC1; GDSC2 0.8786 2.4504 0.8331 24.7508
J82 GDSC1; GDSC2; CTRP2 1.0678 2.5416 1.067 33.1573
TCCSUP GDSC1; GDSC2; CTRP2 1.081 3.4008 1.062 33.13
U-BLC1 CTRP2 1.1189 4.5177 0.9958 33.2173
253J CTRP2 1.4134 2.5881 1.4133 30.8527
SW1710 GDSC1; GDSC2; CTRP2 1.6912 4.3702 1.6245 29.2255
647V GDSC1; GDSC2; CTRP2 1.9233 3.906 1.9048 27.5172
CAL-29 GDSC1; GDSC2; CTRP2 1.971 3.2602 1.9699 27.1412
VM-CUB-1 CTRP2 2.0423 4.0487 2.0197 26.7383
HT-1197 GDSC1; GDSC2; CTRP2 2.0577 3.0809 2.0576 26.5603
BC-3C CTRP2 2.115 2.9187 2.115 26.1784
KMBC-2 CTRP2 2.1267 4.2533 2.0935 26.2119
SCaBER CTRP2 2.1835 2.8486 2.1835 25.7216
253J-BV CTRP2 2.436 3.3631 2.4358 24.0405
T24 GDSC1; GDSC2; CTRP2 2.4727 3.9766 2.4653 23.82
UM-UC-3 GDSC1; GDSC2; CTRP2 2.5251 4.0076 2.5178 23.4701
HT-1376 GDSC1; GDSC2; CTRP2 3.5661 5.6627 3.4336 16.9676
KU-19-19 GDSC1; GDSC2; CTRP2 5.8296 10.3247 3.7227 10.1719
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KGN GDSC1; GDSC2 -2.6239 0.4192 -2.6612 59.1122
SW954 GDSC1; GDSC2 -2.6168 0.2278 -2.6429 59.1602
PA-1 GDSC1; GDSC2 -1.5614 0.1739 -1.5647 49.0086
Ca Ski GDSC1; GDSC2 -1.3564 0.4827 -1.3626 46.9637
NEC8 GDSC1; GDSC2 -1.2028 0.7548 -1.2138 45.4414
ACC-OV7 GDSC1; GDSC2 -0.8231 2.5998 -1.0269 42.2833
CAL-39 GDSC1; GDSC2 -0.7913 0.5987 -0.7932 41.2858
ME-180 GDSC1; GDSC2 -0.7307 2.0319 -0.827 41.0471
TC-YIK GDSC2 -0.7179 1.1076 -0.7307 40.5978
SW962 GDSC1; GDSC2 -0.6793 0.701 -0.6815 40.1635
BPH-1 GDSC1; GDSC2 -0.6027 1.6858 -0.6497 39.5912
OVMIU GDSC1; GDSC2 -0.5342 1.5011 -0.5626 38.8271
C-33 A GDSC1; GDSC2 -0.5013 1.5333 -0.5306 38.5024
NT2-D1 GDSC1; GDSC2 -0.4097 2.0651 -0.4889 37.8072
PWR-1E GDSC2 -0.4091 1.2177 -0.4186 37.4874
SiSo GDSC1; GDSC2 -0.3692 2.4728 -0.5103 37.6673
HEY GDSC1; GDSC2 -0.1475 1.8152 -0.1835 34.9926
OV17R GDSC1; GDSC2 -0.1468 1.5679 -0.1649 34.898
LB831-BLC GDSC1; GDSC2 -0.0078 2.2167 -0.0806 33.7712
PEO1 GDSC1; GDSC2 0.0363 2.2759 -0.0418 33.3569
HeLa GDSC1; GDSC2; CTRP2 0.1958 1.9317 0.1948 38.9675
OVCA433 GDSC1; GDSC2 0.2152 2.8483 0.0481 32.0046
HT-3 GDSC1; GDSC2 0.4584 2.1724 0.4197 28.9315
DoTc2 4510 GDSC1; GDSC2 0.4944 2.3965 0.4308 28.6971
C-4-I GDSC1; GDSC2 0.5183 2.8091 0.3855 28.8113
UWB1.289 GDSC1; GDSC2 0.6169 6.8929 -1.0234 34.3687
JHOS-3 GDSC1; GDSC2 0.8231 3.2912 0.6033 26.2182
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 0.9247 3.6964 0.5947 25.7888
OVCA420 GDSC1; GDSC2 1.1019 2.212 1.0895 22.3407
NCC-IT GDSC1; GDSC2 1.299 2.7146 1.2455 20.5743
SKN GDSC1; GDSC2 1.458 2.4523 1.4435 18.7779
JAR GDSC1; GDSC2 1.5073 2.8592 1.446 18.525
DSH1 GDSC1; GDSC2 2.0073 3.7095 1.7654 14.5005
MS751 GDSC1; GDSC2 2.0387 4.4916 1.4907 15.9563
JEG-3 GDSC1; GDSC2 2.2046 4.2199 1.7784 13.5965
SiHa GDSC1; GDSC2 2.8859 3.6295 2.7373 5.2024
SKG-IIIa GDSC1; GDSC2 2.9121 3.4214 2.8441 4.4788
HEC-1 GDSC1; GDSC2 3.6951 5.8792 2.3394 5.2159
SW756 GDSC1; GDSC2 5.0508 9.1061 1.7124 6.0916
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 ClinicalTrials.gov (NCT01147484) A Study of Foretinib in Patients With Recurrent/Metastatic Breast Cancer (IND197). U.S. National Institutes of Health.
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