Details of the Drug

General Information of Drug (ID: DMHKZLF)

Drug Name
OSI-906
Synonyms
Linsitinib; 867160-71-2; OSI-906; Linsitinib(OSI-906); OSI906; OSI 906; OSI-906AA; OSI-906 (Linsitinib); UNII-15A52GPT8T; Kinome_3532; ASP-7487; 3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol; 15A52GPT8T; CHEMBL1091644; MMV676605; cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol; C26H23N5O; cis-3-(8-amino-1-(2-phenyl-7-quinolinyl)imidazo(1,5-a)pyrazin-3-yl)-1-methylcyclobutanol; Linsitinib [USAN:INN]; OSI906/Linsitinib/; Linsitinib; OSI-906
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 3 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 421.5
Logarithm of the Partition Coefficient (xlogp) 4.2
Rotatable Bond Count (rotbonds) 3
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C26H23N5O
IUPAC Name
3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol
Canonical SMILES
CC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O
InChI
InChI=1S/C26H23N5O/c1-26(32)14-19(15-26)25-30-22(23-24(27)28-11-12-31(23)25)18-8-7-17-9-10-20(29-21(17)13-18)16-5-3-2-4-6-16/h2-13,19,32H,14-15H2,1H3,(H2,27,28)
InChIKey
PKCDDUHJAFVJJB-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
11640390
ChEBI ID
CHEBI:91402
CAS Number
867160-71-2
UNII
15A52GPT8T
DrugBank ID
DB06075
TTD ID
D01GFX
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Insulin-like growth factor I receptor (IGF1R) TTHRID2 IGF1R_HUMAN Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
HLA class I histocompatibility antigen, alpha chain G (HLA-G) OTMLK1KN HLAG_HUMAN Gene/Protein Processing [3]
Proliferation marker protein Ki-67 (MKI67) OTA8N1QI KI67_HUMAN Gene/Protein Processing [3]
Transferrin receptor protein 1 (TFRC) OT8ZPBDL TFR1_HUMAN Gene/Protein Processing [3]
Tumor protein 63 (TP63) OT0WOOKQ P63_HUMAN Gene/Protein Processing [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Solid tumour/cancer
ICD Disease Classification 2A00-2F9Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Insulin-like growth factor I receptor (IGF1R) DTT IGF1R 1.64E-01 0.25 0.64
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 6.1279 14.9722 -0.3632 14.6667
ES1 GDSC1; GDSC2 -1.558 4.8141 -2.4746 49.2809
EW-11 GDSC1; GDSC2 0.357 7.1684 -1.4105 31.8214
SK-ES-1 GDSC1; GDSC2; CTRP2 0.662 6.6831 -0.2681 32.1822
EW-18 GDSC1; GDSC2 0.9044 9.7017 -2.0536 31.8503
EW-1 GDSC1; GDSC2 0.9424 8.4141 -1.4034 29.7008
SK-N-MC CTRP2 1.195 7.744 -0.1107 30.0032
EW-16 GDSC1; GDSC2 1.4788 9.8742 -1.5935 28.5749
ES5 GDSC1; GDSC2 1.6195 7.5868 -0.3545 23.4317
TC71 CTRP2 1.7194 8.9972 -0.1018 28.4031
EW-12 GDSC2 1.7843 5.4078 0.8267 20.8237
EW-7 GDSC1; GDSC2 1.8789 8.7622 -0.6779 23.9717
EW-3 GDSC1; GDSC2 2.1782 10.8465 -1.4314 25.9221
ES8 GDSC1; GDSC2 2.3185 9.2391 -0.5095 21.9737
U2OS GDSC1; GDSC2; CTRP2 2.6373 9.3465 0.6626 23.3342
NOS-1 [Human HNSCC] GDSC1; GDSC2 2.6861 10.313 -0.7167 21.7987
EW-22 GDSC2 2.7743 9.2233 -0.0966 18.9015
A-673 GDSC1; GDSC2; CTRP2 3.0086 8.2507 1.5383 19.1347
TC-71 GDSC1; GDSC2 3.2489 9.0689 0.3873 15.4051
SaOS-2 GDSC1; GDSC2 3.4519 12.7308 -1.2747 21.968
EW-24 GDSC1; GDSC2 3.5832 5.2323 2.5748 3.3506
CHSA0108 GDSC1; GDSC2 3.9613 11.1657 -0.0807 18.4829
MHH-ES-1 GDSC1; GDSC2; CTRP2 4.0223 11.6239 0.8684 19.2304
HuO9 GDSC1; GDSC2 4.0449 10.1373 0.4964 13.001
H-EMC-SS GDSC1; GDSC2 4.0523 11.7021 -0.2761 16.5277
ES7 GDSC1; GDSC2 4.2131 8.1523 1.6031 7.1088
SK-PN-DW GDSC1; GDSC2 4.2502 13.0227 -0.7782 18.1798
CADO-ES1 GDSC2 4.3161 6.6603 2.3906 2.961
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 4.4152 13.6078 0.2277 20.6124
CHSA8926 GDSC1; GDSC2 4.5213 6.721 2.4873 2.2069
NY GDSC1; GDSC2 4.5334 7.8534 1.9688 4.6775
CHSA0011 GDSC1; GDSC2 4.7479 6.7673 2.5923 1.7724
SJSA-1 GDSC1; GDSC2; CTRP2 4.9316 11.559 1.6927 14.1643
EW-13 GDSC1; GDSC2 5.0426 11.0927 0.7603 9.7073
U-CH2 GDSC2 5.1036 7.0806 2.6382 1.1676
ES6 GDSC1; GDSC2 5.3544 14.6695 -0.76 15.7935
HOS GDSC1; GDSC2; CTRP2 5.3664 7.1446 4.2491 2.7704
SW1353 CTRP2 5.8945 9.5081 3.4753 5.1239
Hs 822.T CTRP2 5.9526 6.8895 4.7242 0.3191
ES4 GDSC1; GDSC2 6.0476 14.1978 -0.0465 11.5602
HuO-3N1 GDSC1; GDSC2 6.6276 15.1073 -0.0961 10.8041
CAL-78 GDSC1; GDSC2; CTRP2 8.4012 16.9039 1.6244 8.8179
MG-63 GDSC1; GDSC2; CTRP2 8.9627 17.7215 1.5976 8.2127
CAL-72 GDSC1; GDSC2 9.3833 20.2932 -0.8029 9.6425
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 217 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 4.6429 6.1552 4.1271 4.7077
JM1 GDSC1; GDSC2; CTRP2 3.8355 7.3411 2.7803 12.1376
NCI-H929 GDSC2; CTRP2 -2.2111 0.8364 -2.2259 48.3523
KHM-1B CTRP2 -2.0073 0.3554 -2.0103 46.9849
A4/Fukuda GDSC1; GDSC2; CTRP2 -1.909 3.6628 -2.2164 46.6893
KMS-34 CTRP2 -1.1722 0.1496 -1.1723 41.4162
MM1.S GDSC2; CTRP2 -0.8465 1.0558 -0.8485 39.2525
PL-21 GDSC1; GDSC2 -0.4694 8.8175 -2.9902 43.6989
HuT 78 CTRP2 0.2302 272.2526 -132.5924 49.4568
Karpas-620 GDSC1; GDSC2; CTRP2 0.3703 6.0188 -0.3525 33.4113
KMS-11 GDSC2; CTRP2; CTRP1 0.4769 7.5284 -0.7806 34.2788
KMS-18 CTRP2 0.5342 2.6975 0.5142 30.1143
PL21 CTRP2; CTRP1 0.5806 5.1997 0.1324 31.2845
KMS-20 CTRP2 0.619 4.1087 0.4344 30.1019
KMS-12-BM GDSC1; GDSC2; CTRP2 0.6761 6.4693 -0.1759 31.8609
KMS-21-BM CTRP2 0.6936 3.9996 0.5352 29.5188
MOLP-8 GDSC1; GDSC2; CTRP2 0.8359 9.2146 -1.1044 33.8613
KMS-28BM CTRP2 1.1425 5.9186 0.5189 28.1336
KY821 GDSC1; GDSC2 1.3855 6.9538 -0.2828 23.882
OPM-2 GDSC1; GDSC2; CTRP2 1.4171 3.7367 1.3512 24.3883
RS4;11 GDSC1; GDSC2; CTRP2 1.615 7.5951 0.392 27.1195
EoL-1 GDSC1; GDSC2; CTRP2 1.769 3.5981 1.737 21.9288
NB4 GDSC1; GDSC2; CTRP2 1.7876 7.9525 0.4228 26.5098
LP-1 GDSC1; GDSC2; CTRP2; CTRP1 1.8864 7.4127 0.7575 25.1403
OCI-Ly7 GDSC2 1.8916 7.1892 0.0969 24.3049
ML-2 GDSC1; GDSC2 2.0024 8.5755 -0.4719 22.7456
SKM-1 GDSC2; CTRP2; CTRP1 2.0729 5.9051 1.5353 21.7885
AML-193 CTRP2 2.1764 5.2629 1.8522 20.2472
ATN-1 GDSC1; GDSC2 2.3278 7.0687 0.567 17.0169
L-363 GDSC1; GDSC2; CTRP2 2.3548 7.7171 1.1115 22.4778
GDM-1 GDSC1; GDSC2; CTRP2; CTRP1 2.3632 9.298 0.4193 24.9731
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 2.3633 7.378 1.2653 21.8867
SUP-B8 GDSC2 2.5242 7.2182 0.6747 18.9429
Sc-1 GDSC1 2.5579 5.3741 0.2386 5.2814
HL-60 GDSC1; GDSC2; CTRP2 2.7303 8.7363 1.0373 21.7417
ALL-PO GDSC1; GDSC2 2.7357 8.3912 0.2836 17.2426
Kasumi-1 GDSC2; CTRP2 2.9643 5.7952 2.5326 15.4155
HPB-ALL CTRP2 2.9735 6.8027 2.1442 16.8779
SK-MM-2 GDSC1; GDSC2; CTRP2 3.1421 6.3091 2.5251 14.9459
NOMO-1 GDSC1; GDSC2; CTRP2; CTRP1 3.2477 8.3583 1.7329 17.8499
GR-ST GDSC1; GDSC2 3.2959 6.5614 1.6805 8.7149
AMO1 GDSC1; GDSC2; CTRP2; CTRP1 3.3585 11.1067 0.5227 22.0724
697 GDSC1; GDSC2; CTRP2 3.3914 4.7259 3.3164 11.27
Peer CTRP2 3.5621 5.5728 3.2569 10.9764
LC4-1 GDSC1; GDSC2 3.6019 6.3454 2.0367 6.1286
NALM-6 GDSC1; GDSC2; CTRP2 3.6424 6.0885 3.1419 11.193
MHH-PREB-1 GDSC1; GDSC2 3.6537 6.2785 2.1102 5.6295
RPMI-8226 GDSC1; GDSC2; CTRP2; CTRP1 3.689 7.4829 2.5765 13.4019
SCC-3 GDSC1; GDSC2 3.7079 4.8604 2.8457 1.7159
Ri-1 CTRP2 3.7125 9.4935 1.6314 17.0458
MHH-CALL-2 GDSC2 3.7185 10.1032 0.2558 14.8907
RPMI-8402 GDSC1; GDSC2; CTRP2 3.7211 5.9859 3.2668 10.4948
ALL-SIL GDSC1; GDSC2 3.7223 11.1914 -0.2843 17.331
TUR GDSC1; GDSC2 3.7484 5.7637 2.4357 3.7365
Karpas-45 GDSC1; GDSC2 3.7661 7.8977 1.3928 9.1252
MV4-11 GDSC1; GDSC2 3.7707 7.7795 1.4552 8.7922
BALL-1 GDSC1; GDSC2 3.7982 6.5045 2.108 5.3357
PF-382 GDSC1; GDSC2; CTRP2 3.8015 6.3346 3.2031 10.5292
HDLM-2 GDSC1; GDSC2; CTRP2 3.833 6.7642 3.044 11.0817
Pfeiffer CTRP2 3.8383 5.7557 3.4832 9.3374
Mono-Mac-6 GDSC1; GDSC2; CTRP2 3.8416 8.2862 2.3374 13.9199
OCI-AML-3 GDSC1; GDSC2; CTRP2; CTRP1 3.8443 8.197 2.3904 13.7786
OCI-AML-5 GDSC1; GDSC2; CTRP2 3.8873 10.1799 1.4584 17.3153
JJN-3 GDSC1; GDSC2; CTRP2 3.8895 8.0074 2.517 13.0773
SET-2 CTRP2 3.89 6.178 3.3622 9.6692
Karpas-1106P GDSC2 3.9016 7.1074 1.8879 6.2665
HEL GDSC1; GDSC2; CTRP2 3.9091 5.8651 2.5002 2.7922
JVM-2 GDSC1; GDSC2; CTRP2 3.9121 6.4807 2.2033 4.1549
JVM-3 GDSC1; GDSC2; CTRP2 3.9499 5.6105 3.6587 8.3545
EJM GDSC1; GDSC2; CTRP2; CTRP1 3.9761 9.7072 1.7804 15.9255
BE-13 GDSC1; GDSC2 3.9839 6.8204 2.089 5.0627
EM-2 GDSC1; GDSC2; CTRP2 4.0211 5.5092 3.7735 7.7172
Mono-Mac-1 CTRP2 4.0242 6.3354 3.4306 9.0491
BONNA-12 GDSC2 4.0274 6.8353 2.1128 5.8287
VAL GDSC1; GDSC2 4.0354 7.3758 1.8544 6.1695
NCO2 CTRP2 4.0479 6.0229 3.5924 8.3463
NK-92MI GDSC1; GDSC2 4.0547 6.0831 2.4939 3.4555
Daudi GDSC1; GDSC2; CTRP2 4.0657 4.8853 4.0151 6.6944
KE-37 GDSC1; GDSC2; CTRP2 4.0669 5.3498 3.881 7.1803
HH [Human lymphoma] GDSC1; GDSC2; CTRP2 4.0833 6.9466 3.2086 9.7966
KMM-1 CTRP2 4.0846 7.2387 3.0718 10.3504
Reh GDSC1; GDSC2; CTRP2 4.1032 9.1592 2.1581 14.046
F-36P CTRP2 4.1176 6.7834 3.3188 9.2652
MOLT-3 CTRP2 4.1238 5.4752 3.8962 6.961
GA-10 GDSC2; CTRP2 4.1303 5.2531 3.9829 6.616
Jurkat GDSC2; CTRP2 4.1342 6.0371 2.5668 2.153
SU-DHL-6 GDSC1; GDSC2; CTRP2 4.1449 6.4301 3.5095 8.4274
Loucy GDSC1; GDSC2 4.1542 6.4598 2.3806 3.2731
SU-DHL-16 GDSC1; GDSC2 4.217 5.9736 2.6469 2.2661
HAL-01 GDSC1; GDSC2 4.219 9.4894 0.9501 10.4018
DG-75 GDSC1; GDSC2 4.2204 6.8108 2.2575 3.7734
EB1 CTRP2 4.2318 5.4674 4.0145 6.207
P32/ISH GDSC1; GDSC2 4.2508 7.1737 2.1044 4.4881
RPMI-8866 GDSC1; GDSC2 4.254 6.1277 2.5987 2.0606
NKM-1 GDSC1; GDSC2 4.2785 8.6888 1.388 9.6404
REC-1 CTRP2 4.2877 6.8776 3.4402 8.3613
KM-H2 GDSC1; GDSC2; CTRP2 4.3008 6.834 2.2993 3.0899
U-698-M GDSC1; GDSC2 4.3074 8.4998 1.5012 7.4436
DND-41 GDSC1; GDSC2; CTRP2 4.3425 7.6623 3.1127 9.5833
H9 GDSC1; GDSC2 4.3454 8.4071 1.5736 7.0028
CESS GDSC1; GDSC2 4.3548 7.8079 1.8705 5.4814
ARH-77 GDSC1; GDSC2 4.3585 6.3452 2.5618 2.0855
Jiyoye GDSC1; GDSC2 4.3611 7.4556 2.0438 4.5987
CML-T1 GDSC2; CTRP2 4.3859 6.4571 3.7351 6.9217
Kasumi-2 CTRP2 4.4013 6.2999 3.8241 6.5224
OCI-Ly19 GDSC1; GDSC2; CTRP2 4.4109 7.0949 3.453 8.0215
SIG-M5 GDSC1; GDSC2; CTRP2 4.4134 7.8314 3.0955 9.4962
Mino CTRP2 4.4174 5.788 4.0748 5.4732
MOLT-16 GDSC1; GDSC2; CTRP2 4.4271 5.9226 4.0242 5.6502
ST486 GDSC1; GDSC2; CTRP2 4.4309 5.54 4.1958 4.9605
L-540 GDSC1; GDSC2; CTRP2 4.4474 7.5042 3.2874 8.6242
JeKo-1 GDSC2; CTRP2 4.4737 5.9674 4.0505 5.4277
BV-173 GDSC1; GDSC2; CTRP2 4.4795 8.5002 2.8257 10.4723
IM-9 GDSC1; GDSC2 4.4928 6.2528 2.6789 1.3959
KMOE-2 GDSC1; GDSC2 4.4949 10.9744 0.4238 12.3814
MN-60 GDSC1; GDSC2 4.5022 7.3928 2.166 3.7594
WSU-NHL GDSC1; GDSC2 4.5105 13.1528 -0.6415 17.0528
ME1 GDSC1; GDSC2 4.5132 5.9374 2.823 0.8002
OCI-AML-2 GDSC1; GDSC2; CTRP2 4.5295 9.1986 2.524 11.6162
MHH-CALL-4 GDSC2; CTRP2 4.5352 8.332 2.9591 9.7977
Ki-JK CTRP2 4.5362 7.209 3.5141 7.4853
M-07e CTRP2 4.5388 7.4438 3.4011 7.9492
CTV-1 GDSC1; GDSC2 4.5392 8.9133 1.4642 7.1894
P31/FUJ GDSC1; GDSC2; CTRP2 4.5476 6.2111 4.0086 5.4181
RCH-ACV GDSC2; CTRP2 4.5567 8.1818 3.0527 9.3615
MOLM-16 GDSC2; CTRP2; CTRP1 4.5593 9.2528 2.5323 11.5983
BC-1 GDSC1; GDSC2 4.5612 12.7534 -0.405 15.9588
MOLM-13 GDSC1; GDSC2; CTRP2 4.5964 8.3343 3.0126 9.4442
EB2 GDSC1; GDSC2 4.5965 6.2941 2.7156 1.1346
MOTN-1 CTRP2 4.622 6.902 3.7438 6.3409
SUP-T1 GDSC1; GDSC2; CTRP2 4.626 9.8218 2.2986 12.3425
BL-70 CTRP2; CTRP1 4.63 5.5195 4.4168 3.6564
P12-Ichikawa GDSC1; GDSC2; CTRP2 4.6372 6.4334 3.9869 5.2988
TK [Human B-cell lymphoma] GDSC1; GDSC2 4.662 9.8969 1.0733 8.9045
HD-MY-Z CTRP2 4.6695 6.0188 4.218 4.2722
DoHH2 GDSC1; GDSC2 4.6723 6.1694 2.8042 0.7352
WIL2 NS GDSC1; GDSC2 4.6807 6.3867 2.7191 1.0396
Karpas-422 GDSC1; GDSC2; CTRP2 4.7104 6.1032 4.2162 4.1844
DB GDSC1; GDSC2; CTRP2 4.7141 6.0148 4.2624 3.9853
Namalwa GDSC1; GDSC2; CTRP2 4.7293 6.999 3.7935 5.8997
Hs 445 GDSC1; GDSC2 4.7306 6.4704 2.7089 1.0322
CCRF-CEM GDSC1; GDSC2 4.7574 6.8312 2.5698 1.559
KE-97 CTRP2 4.7654 5.8717 4.3802 3.3814
Hs 611.T CTRP2 4.7721 6.1811 4.2357 3.9641
OCI-Ly3 CTRP2 4.7954 5.8912 4.399 3.2351
SUP-HD1 GDSC1; GDSC2; CTRP2 4.8004 7.2972 3.7088 6.1034
U266B1 GDSC1; GDSC2; CTRP2 4.8019 8.1906 3.2649 7.9609
SU-DHL-8 GDSC1; GDSC2; CTRP2 4.8136 6.6037 4.065 4.5851
SU-DHL-5 GDSC1; GDSC2; CTRP1 4.823 6.012 4.3738 3.6913
CA46 GDSC1; GDSC2; CTRP2 4.8273 6.4124 4.172 4.1084
NU-DUL-1 GDSC1; GDSC2; CTRP2; CTRP1 4.8276 6.4898 4.1425 4.3185
K-562 GDSC1; GDSC2; CTRP2 4.8443 6.7467 4.0212 4.7032
MOLT-4 GDSC1; GDSC2 4.8722 9.8762 1.2295 7.7462
BL-41 GDSC1; GDSC2 4.8843 6.912 2.6011 1.3024
JURL-MK1 GDSC1; GDSC2; CTRP2 4.9139 7.8804 3.5162 6.6797
TF-1 CTRP2 4.9269 6.1786 4.3766 3.0424
VL51 GDSC1; GDSC2 4.9324 6.8408 2.6544 1.0561
LAMA-84 GDSC1; GDSC2; CTRP2 4.9383 6.9665 2.6053 1.1118
HuNS1 CTRP2 4.9525 9.2793 2.8498 9.3968
Ku812 GDSC1; GDSC2; CTRP2 4.9562 8.2034 3.3908 7.1224
RL GDSC1; GDSC2; CTRP2 4.9578 6.3276 4.3293 3.1772
MY-M12 GDSC1; GDSC2 4.9712 10.9802 0.7649 11.5862
A3/Kawakami GDSC1; GDSC2; CTRP2 4.9866 7.7831 3.6266 6.0721
KG-1 GDSC1; GDSC2 5.0026 6.9602 2.6393 1.0512
KYO-1 CTRP2 5.0144 6.9304 4.0763 4.1274
ROS-50 GDSC1; GDSC2 5.024 10.6042 0.9831 10.2728
L-428 GDSC1; GDSC2; CTRP2 5.026 6.9904 4.056 4.1902
RPMI-6666 GDSC1; GDSC2; CTRP2 5.0315 7.3534 3.8791 4.9232
RC-K8 GDSC1; GDSC2 5.047 7.3002 2.52 1.4616
KMS-27 CTRP2 5.0643 14.8059 0.1802 19.4284
P30/OHK GDSC1; GDSC2 5.0657 11.3287 0.6622 10.1299
KO52 CTRP2 5.0836 6.2802 4.4589 2.3865
Karpas-231 GDSC1; GDSC2 5.0933 6.6509 2.802 0.4679
Karpas-299 GDSC1; GDSC2; CTRP2 5.0951 6.8582 4.1794 3.5392
MOLM-6 CTRP2 5.1013 8.5198 3.3539 6.9962
HC-1 GDSC1; GDSC2 5.1027 8.0319 2.2332 2.6008
SUP-M2 GDSC1; GDSC2; CTRP2 5.1105 6.4218 4.41 2.5416
SU-DHL-10 GDSC2; CTRP2 5.1129 6.5402 4.3528 2.7774
OCI-M1 GDSC1; GDSC2; CTRP2 5.1248 6.2485 4.5079 2.1045
HEL 92.1.7 CTRP2 5.1301 6.3587 4.4573 2.3073
SUP-B15 GDSC1; GDSC2; CTRP2 5.1576 6.4799 4.4186 2.4198
WSU-DLCL2 GDSC1; GDSC2; CTRP2; CTRP1 5.1638 7.1953 4.0768 3.926
CMK CTRP2 5.1891 6.2515 4.5568 1.7868
BC-3 GDSC1; GDSC2 5.195 6.7696 2.7994 0.5084
Raji GDSC1; GDSC2; CTRP2 5.2099 6.5407 4.4293 2.2829
EHEB GDSC1; CTRP2 5.2201 6.9222 4.2477 3.0248
SU-DHL-1 GDSC1; GDSC2; CTRP2 5.2432 7.9126 3.7725 4.9746
Ci-1 CTRP2 5.2761 6.2708 4.6119 1.4166
Ramos.2G6.4C10 GDSC1; GDSC2 5.2911 6.6333 2.8865 0.1993
CTB-1 GDSC1; GDSC2 5.3056 11.6847 0.6559 11.4371
MHH-CALL-3 CTRP2 5.3171 6.7562 4.4038 2.2099
YT GDSC1; GDSC2 5.3301 6.9175 2.7991 0.4365
SUP-T11 CTRP2 5.3376 7.0032 4.2973 2.6175
KCL-22 GDSC1; GDSC2; CTRP2 5.3656 7.9186 3.8654 4.3695
Farage GDSC1; GDSC2 5.3841 7.0309 2.7788 0.3877
MOLT-13 GDSC2; CTRP2 5.4059 7.5442 4.0815 3.401
MC116 GDSC1; GDSC2; CTRP2 5.4075 9.0563 3.3324 6.5239
Toledo CTRP2 5.4258 7.3175 4.2079 2.8448
JSC-1 GDSC1; GDSC2 5.4698 7.5805 2.6061 0.8153
MEG-01 GDSC1; GDSC2 5.7112 7.7829 2.6317 0.6016
QIMR-WIL GDSC1; GDSC2 5.857 8.1858 2.5399 0.9308
CRO-AP2 GDSC2 5.8958 7.5814 2.7769 0.2642
ME1 CTRP2 5.9309 7.5204 4.4438 1.241
NU-DHL-1 CTRP2 6.0327 7.6564 4.441 1.1476
DEL GDSC1; GDSC2; CTRP2 6.0499 7.7537 4.4076 1.2486
L-1236 GDSC1; GDSC2; CTRP2 6.0894 9.0353 3.8382 3.698
U-937 CTRP2; CTRP1 6.2398 11.3587 2.8307 7.296
HT GDSC1; GDSC2; CTRP2 6.2613 10.2391 3.3779 4.9736
OCI-Ly10 CTRP2; CTRP1 6.2622 8.2617 4.3143 1.431
P3HR-1 CTRP2 6.2684 11.9234 2.564 8.2568
Granta-519 GDSC1; GDSC2; CTRP2 6.3639 8.1708 4.3957 1.0033
THP-1 GDSC1; GDSC2; CTRP2; CTRP1 6.6189 10.3287 3.5828 3.7562
KOPN-8 GDSC1; GDSC2 6.83 18.9954 -1.8188 16.9535
SR GDSC1; GDSC2; CTRP2 6.9417 11.7939 3.0895 5.1884
MOLP-2 CTRP2 6.989 13.6596 2.23 8.4859
MLMA GDSC1; GDSC2 7.0215 13.3435 0.9551 5.7653
SU-DHL-4 GDSC1; GDSC2; CTRP2; CTRP1 7.1567 14.1626 2.1145 8.7584
⏷ Show the Full List of 217 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 4.9661 7.3967 3.8024 5.3737
TE8 CTRP2 4.9897 7.6711 3.6852 5.8196
T.T GDSC1; GDSC2 3.2152 11.5199 -0.8663 24.1323
TE-11 GDSC1; GDSC2; CTRP2 4.3822 6.3872 3.7645 6.8111
KYSE-140 GDSC1; GDSC2; CTRP2 4.6117 9.2612 2.5653 11.2724
EC-GI-10 GDSC1; GDSC2; CTRP2 4.933 6.5886 4.1777 3.864
OE33 GDSC1; GDSC2; CTRP2 5.0218 9.1209 2.9873 8.6866
OE21 GDSC1; GDSC2; CTRP2 5.1044 8.3563 3.4382 6.6361
TE-14 CTRP2 5.119 7.9616 3.6475 5.7294
TE-6 GDSC1; GDSC2; CTRP2 5.1935 7.4557 3.2115 2.1527
TE-4 GDSC2; CTRP2 5.2707 6.8327 4.3311 2.5888
TE-10 GDSC1; GDSC2; CTRP2 5.3885 9.7422 2.9757 8.0478
TE-1 GDSC1; GDSC2; CTRP2 5.4075 9.832 2.946 8.1375
TE-5 GDSC1; GDSC2; CTRP2 5.5075 7.3491 4.2515 2.5383
KYSE-150 GDSC1; GDSC2; CTRP2 5.6311 18.9859 -1.4437 23.1628
TE-9 GDSC1; GDSC2; CTRP2 5.8798 9.1354 2.8544 2.7523
TE-15 GDSC1; GDSC2 5.8889 14.241 -0.1748 12.3846
KYSE-180 GDSC1; GDSC2; CTRP2 5.8996 9.3121 3.5745 4.7101
KYSE-410 GDSC1; GDSC2; CTRP2 5.9303 8.5452 3.9659 3.0816
KYSE-520 GDSC1; GDSC2; CTRP2 5.9772 13.8166 1.4094 13.3001
KYSE-270 GDSC1; GDSC2 6.0722 8.2698 2.5972 0.5181
KYSE-450 GDSC1; GDSC2; CTRP2 6.0762 7.758 4.4204 1.1774
KYSE-30 CTRP2 6.5264 9.1304 4.0643 1.9884
KYSE-510 GDSC1; GDSC2; CTRP2 6.9742 8.9133 4.3845 0.6257
COLO 680N GDSC1; GDSC2; CTRP2 7.2125 13.954 2.2413 8.1207
TE-8 GDSC1; GDSC2 9.0844 23.6882 -2.5526 15.7575
KYSE-70 GDSC1; GDSC2; CTRP2 9.554 17.6303 1.9938 6.1757
OE19 GDSC1; GDSC2; CTRP2 9.7783 20.3856 0.8684 9.7101
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 6.5188 11.8917 2.7581 7.0906
PaTu 8988s CTRP2 1.3818 8.5199 -0.2406 29.8245
TCC-Pan2 CTRP2 2.8719 7.6467 1.6733 18.9704
PaTu 8902 GDSC1; GDSC2; CTRP2; CTRP1 3.8015 12.0643 0.4601 21.2461
Panc 08.13 GDSC1; GDSC2; CTRP2 4.4575 11.4085 1.3609 16.4348
AsPC-1 GDSC1; GDSC2; CTRP2 4.6824 9.8219 2.3476 12.0243
BxPC-3 GDSC1; GDSC2; CTRP2 4.8924 10.0266 2.4255 11.2782
SW1990 GDSC1; GDSC2; CTRP2 4.9636 6.6192 4.1887 3.7558
SNU-410 CTRP2 5.1569 10.5878 2.3659 11.007
HuP-T4 GDSC1; GDSC2; CTRP2 5.1885 9.2838 3.0435 8.1329
Hs 766T GDSC1; GDSC2; CTRP2 5.2066 7.1235 4.1367 3.5136
KP-3 GDSC1; GDSC2; CTRP2 5.303 10.8026 2.3778 10.6821
PK-45H CTRP2 5.4933 7.8628 3.9896 3.6392
KP-4 GDSC1; GDSC2; CTRP2 5.6078 7.2031 4.3907 1.8315
MZ-PC-1 GDSC1; GDSC2 5.6506 13.3033 0.1134 13.4126
SNU-213 CTRP2 5.7433 14.3827 0.9442 15.4547
Panc 10.05 GDSC1; GDSC2 5.7757 16.1818 -1.1955 16.6546
KP-2 GDSC1; GDSC2; CTRP2 5.8326 9.7107 3.3311 5.814
SUIT-2 GDSC1; GDSC2; CTRP2 5.8417 8.0559 4.14 2.5099
SU.86.86 GDSC1; GDSC2; CTRP2 5.8579 7.1497 4.5674 0.8762
Capan-1 GDSC1; GDSC2; CTRP2 5.9841 12.2948 2.1694 10.314
CFPAC-1 GDSC1; GDSC2; CTRP2 6.0421 12.0565 2.3311 9.5656
KP-1N GDSC1; GDSC2 6.1106 14.193 -0.002 11.2617
L3.3 CTRP2 6.22 7.9565 4.412 1.0725
MIA PaCa-2 GDSC1; GDSC2; CTRP2 6.5982 15.0674 1.2615 12.7949
HPAC GDSC1; GDSC2; CTRP2 6.6137 16.2731 0.6782 14.8708
PL4 GDSC1; GDSC2 6.9334 15.5164 -0.0926 10.3086
HuP-T3 GDSC1; GDSC2; CTRP2 7.002 15.7653 1.2149 12.3143
PSN1 GDSC1; GDSC2; CTRP2 7.019 14.812 1.6923 10.5091
QGP-1 GDSC2; CTRP2 7.0672 13.8037 1.4311 6.9167
Panc 05.04 CTRP2 7.1135 8.9408 4.4341 0.4422
YAPC GDSC1; GDSC2; CTRP2 7.1439 14.2974 2.0292 9.0362
Panc 03.27 GDSC1; GDSC2; CTRP2 7.5484 13.7091 2.5787 6.374
PK-59 CTRP2 7.65 12.3685 3.2584 3.7188
HPAF-II GDSC1; GDSC2; CTRP2 7.9042 17.0739 1.2138 10.9649
Panc 02.03 GDSC1; GDSC2; CTRP2 8.1034 17.1416 1.3159 10.3212
Capan-2 GDSC1; GDSC2; CTRP2 8.5928 19.6314 0.4542 12.6024
DAN-G GDSC1; GDSC2; CTRP2 8.8004 23.1398 -1.0963 17.0161
Panc 04.03 GDSC1; GDSC2; CTRP2 9.6157 24.3493 -1.1153 15.9381
PaTu 8988t GDSC1; GDSC2; CTRP2 11.8851 23.2548 0.8102 7.6457
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 5.3447 12.4869 1.5704 13.839
VMRC-MELG GDSC1; GDSC2 3.9383 10.8443 0.0612 17.8504
RPMI-7951 GDSC1; GDSC2 3.9801 6.3189 2.3302 3.8346
CP50-MEL-B GDSC1; GDSC2 4.1384 12.4324 -0.572 20.2623
COLO 783 GDSC1; GDSC2 4.2185 8.0028 1.6801 8.028
WM35 GDSC1; GDSC2 4.2651 12.8946 -0.7029 20.4905
COLO 792 GDSC1; GDSC2; CTRP2 4.3004 10.9548 1.4484 16.4347
GAK GDSC1; GDSC2 4.3725 5.7858 2.8161 0.9591
CHL-1 GDSC1; GDSC2 4.3852 7.524 2.0273 4.6396
WM88 CTRP2 4.5235 5.5347 4.2944 4.3275
DJM-1 GDSC1; GDSC2 4.565 7.4804 2.1649 4.3989
A-431 GDSC1; GDSC2 4.6424 6.9386 2.4594 2.61
COLO 741 CTRP2 4.6463 9.2703 2.5912 11.0933
HMV-II GDSC1; GDSC2 4.7152 12.5875 -0.2071 14.7847
MMAc-SF GDSC1; GDSC2 4.9338 8.1757 2.0705 4.2761
MeWo GDSC1; GDSC2; CTRP2 4.9697 6.7694 4.1189 4.0367
Mel Ho GDSC1; GDSC2; CTRP2 4.9941 6.3 4.3742 2.9158
Hs 294T CTRP2 5.0925 7.6081 3.8024 5.1283
CJM [Human melanoma] CTRP2 5.1015 5.8035 4.7113 1.2938
IST-MEL1 GDSC1; GDSC2 5.1335 10.2329 1.2345 8.6384
WM115 GDSC1; GDSC2; CTRP2 5.1348 6.2408 4.5198 2.0368
Hs 895.T CTRP2 5.1699 7.2051 4.0667 3.8736
G-361 GDSC1; GDSC2; CTRP2 5.2021 9.0005 3.1962 7.4676
Hs 940.T GDSC1; GDSC2; CTRP2 5.2462 9.0943 3.1851 7.4326
HMCB CTRP2 5.2885 6.146 4.6814 1.1142
IGR-1 GDSC1; GDSC2; CTRP2 5.3023 8.1058 3.723 5.0761
MZ-MEL-7 GDSC1; GDSC2 5.3207 6.8963 2.8031 0.43
SH-4 GDSC1; GDSC2 5.327 10.7806 1.1021 7.5734
WM266-4 CTRP2 5.338 6.7475 4.4234 2.0954
COLO 800 GDSC1; GDSC2; CTRP2 5.3857 7.2249 4.2239 2.8436
A-388 GDSC1; GDSC2 5.3893 7.8826 2.4472 1.7064
COLO 829 GDSC1; GDSC2; CTRP2 5.3966 7.6468 4.0238 3.6562
COLO 679 GDSC1; GDSC2 5.4248 9.5263 1.7477 4.372
Hs 944.T CTRP2 5.4261 8.0093 3.8668 4.2604
LB2518-MEL GDSC1; GDSC2 5.4364 12.7266 0.2438 13.2688
WM1552C GDSC1; GDSC2 5.478 10.7655 1.207 6.828
G-mel GDSC1; GDSC2 5.5035 11.646 0.8075 8.6659
Hs 938.T GDSC1; GDSC2 5.5069 6.8557 2.8877 0.1729
WM983B CTRP2 5.5197 7.8141 4.033 3.4172
HT-144 GDSC1; GDSC2; CTRP2 5.5361 7.5417 4.178 2.7953
IPC-298 GDSC1; GDSC2; CTRP2 5.5404 7.1413 4.375 1.988
LOX-IMVI GDSC1; GDSC2; CTRP2 5.5776 11.4104 2.2941 10.5208
A2058 GDSC1; GDSC2; CTRP2 5.5909 7.9937 3.9967 3.4547
UACC-257 GDSC1; GDSC2; CTRP2 5.5914 9.0974 3.4537 5.7014
WM1799 CTRP2 5.5991 7.989 4.0049 3.4078
Hs 934.T CTRP2 5.6219 7.0321 4.4807 1.4591
MZ-MEL-2 GDSC1; GDSC2 5.7017 16.4225 -1.3665 19.6866
WT2-iPS GDSC1; GDSC2; CTRP2 5.7497 8.6705 3.7802 4.0973
SK-MEL-31 GDSC2; CTRP2 5.7876 8.4374 3.9202 3.469
451Lu GDSC1; GDSC2 5.7922 7.2682 2.8478 0.1684
Hs 839.T CTRP2 5.8 7.1022 4.5561 0.973
IGR-39 CTRP2 5.8099 7.2098 4.5136 1.1159
SK-MEL-5 GDSC1; GDSC2; CTRP2; CTRP1 5.8623 9.5359 3.4495 5.3571
SK-MEL-28 GDSC1; GDSC2; CTRP2; CTRP1 5.8874 7.13 4.6051 0.7824
K029AX CTRP2 5.9139 9.8952 3.2999 5.8135
Malme-3M CTRP2 5.952 11.4249 2.5754 8.7248
WM793 GDSC1; GDSC2; CTRP2 5.9801 8.1658 4.1775 2.1843
CP66-MEL GDSC1; GDSC2 5.9957 15.2418 -0.5836 13.8818
SK-MEL-24 GDSC1; GDSC2; CTRP2 6.0004 13.2752 1.6961 12.1569
Mel JuSo GDSC1; GDSC2; CTRP2 6.0037 9.3113 3.6479 4.2562
LB373-MEL-D GDSC1; GDSC2 6.0353 16.2102 -1.0249 17.6481
SK-MEL-1 GDSC1; GDSC2; CTRP2; CTRP1 6.1963 9.1726 3.8552 3.236
SK-MEL-3 GDSC1; GDSC2; CTRP2 6.2424 13.2654 1.8846 11.0079
SK-MEL-2 GDSC1; GDSC2; CTRP2 6.3481 7.2736 4.743 0.1242
M14 GDSC1; GDSC2 6.4307 16.1609 -0.7279 13.6873
A-375 GDSC1; GDSC2; CTRP2; CTRP1 6.469 14.4272 1.4917 12.2139
Hs 852.T CTRP2; CTRP1 6.5208 14.5193 1.4849 12.1539
UACC-62 GDSC1; GDSC2; CTRP2 6.5361 10.3135 3.5251 4.0145
MDA-MB-435S CTRP2 6.6958 10.5573 3.5126 3.8609
SK-MEL-30 GDSC1; GDSC2; CTRP2 6.9181 8.126 4.6543 0.1193
WM278 GDSC1; GDSC2 7.0447 15.2121 0.1186 9.2665
Hs 936.T CTRP2 7.0653 8.4897 4.5809 0.1871
RVH-421 GDSC1; GDSC2; CTRP2 7.2183 14.202 2.1262 8.5559
A101D GDSC1; GDSC2; CTRP2 7.2502 13.4979 2.4844 7.1291
IGR-37 GDSC1; GDSC2; CTRP2 7.9612 15.6618 1.9253 8.2941
EquiPSC Line K2 GDSC1; GDSC2 6.6844 17.683 -1.2864 17.3399
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACP4 C GDSC2 0.5094 4.8591 -0.2708 26.9244
OACM5.1 C GDSC2 2.4469 8.446 -0.0015 19.376
HCE-4 GDSC1; GDSC2 4.0297 8.3108 1.39 10.2402
TE-12 GDSC1; GDSC2 4.2479 8.681 1.3695 8.2304
ESO-26 GDSC2 4.5648 7.5363 2.1386 3.7935
FLO-1 GDSC2 4.5786 8.7497 1.5705 6.5844
KYSE-220 GDSC1; GDSC2 4.7373 9.9231 1.1135 8.5639
KYSE-50 GDSC1; GDSC2 4.823 12.5891 -0.128 14.2171
ESO-51 GDSC2 4.9585 7.7934 2.2579 2.6723
KYAE-1 GDSC2 5.1758 9.705 1.5115 5.8592
SK-GT-4 GDSC2 6.0904 12.9881 0.5553 8.8501
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 4.8552 6.2999 4.2527 3.7118
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-10 GDSC1; GDSC2 0.5007 7.0247 -1.2003 30.5758
NB(TU)1 GDSC1; GDSC2 0.5695 7.4462 -1.3219 30.7415
NB69 GDSC1; GDSC2 0.8111 7.423 -1.0697 28.9892
SK-N-FI GDSC1; GDSC2; CTRP2 0.8645 6.5912 -0.0167 30.7591
LA-N-6 GDSC1; GDSC2 1.017 9.6764 -1.9339 35.3516
NH-6 CTRP2 1.0372 5.5687 0.5175 28.4704
MHH-NB-11 GDSC1; GDSC2; CTRP2 1.2182 8.033 -0.2053 30.218
NH-12 GDSC1; GDSC2 1.7144 8.2383 -0.5775 24.0697
SiMa GDSC1; GDSC2 2.3834 7.7497 0.2843 18.2227
SJNB-13 GDSC1; GDSC2 2.423 7.51 0.4385 17.3692
SK-N-BE(2)-M17 GDSC1; GDSC2 2.4809 9.6607 -0.573 21.7771
KP-N-RT-BM-1 GDSC2 2.6149 4.6269 2.0156 10.5849
SK-N-DZ GDSC1; GDSC2; CTRP2 2.6809 9.9896 0.4041 24.1139
KP-N-SI9s CTRP2 2.9311 8.2393 1.466 19.6111
SK-N-SH GDSC1; GDSC2; CTRP2 3.0323 9.8584 0.8075 21.8023
SJNB-12 GDSC1; GDSC2 3.0525 7.2539 1.1272 14.5784
TGW GDSC1; GDSC2 3.1735 10.958 -0.6205 20.1153
SK-N-MC-IXC GDSC1; GDSC2 3.5236 10.2708 0.0141 19.2589
CHP-134 GDSC2 3.7955 7.9849 1.3724 9.1658
SK-N-BE(2) CTRP2 4.0643 10.297 1.5624 16.5109
CHP-212 GDSC1; GDSC2; CTRP2 4.2029 13.5971 0.048 21.6667
SJNB-17 GDSC2 4.4311 7.3589 2.1361 4.826
SJNB-7 GDSC1; GDSC2 4.5 7.6919 2.0235 4.4633
KP-N-YS GDSC1; GDSC2 4.8441 8.6048 1.8157 5.8912
IMR-5 GDSC1; GDSC2 4.9022 9.5487 1.4067 6.8237
SJNB-14 GDSC1; GDSC2 5.0479 11.6208 0.5081 10.8876
GOTO GDSC1; GDSC2 5.1378 10.2555 1.2267 7.2954
KP-N-YN GDSC1; GDSC2; CTRP2 5.2687 10.8929 2.3049 11.0453
NB1 GDSC1; GDSC2; CTRP2 5.2937 6.3982 4.5624 1.5927
SJNB-6 GDSC1; GDSC2 5.454 14.0123 -0.3675 16.1281
SJNB-5 GDSC1; GDSC2 5.7038 13.9947 -0.1834 14.7404
GI-ME-N GDSC1; GDSC2 5.74 17.8118 -2.0199 19.5929
SK-N-AS GDSC1; GDSC2; CTRP2 5.9023 13.3637 1.5763 12.7933
Kelly GDSC1; GDSC2; CTRP2 6.3153 13.2121 1.9653 10.5704
CHP-126 GDSC1; GDSC2; CTRP2 8.0997 19.331 0.2594 13.946
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1196 CTRP2 4.7293 11.1172 1.7416 14.38
SNU-478 CTRP2 5.1454 6.3832 4.4572 2.2799
HuH-28 CTRP2 5.3448 8.5577 3.5314 5.8025
SNU-1079 CTRP2 5.4013 9.8069 2.9536 8.117
SNU-869 CTRP2 5.7399 7.5241 4.3252 1.9146
HuCC-T1 GDSC1; GDSC2; CTRP2 5.7957 7.8436 4.2105 2.2927
SNU-308 CTRP2 6.1094 10.8335 2.9823 6.8079
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 90 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC202 GDSC1 1.4255 2.8639 0.6592 5.2506
HCC1599 GDSC1; GDSC2 2.2337 7.1718 0.4289 21.2488
DU4475 GDSC1; GDSC2; CTRP2 3.0011 4.9956 2.8277 14.2179
MCF-7 GDSC1; GDSC2; CTRP2; CTRP1 3.1038 8.4829 1.5326 18.9882
AU565 GDSC1; GDSC2 3.5214 7.3094 1.4919 9.1652
MDA-MB-453 GDSC1; GDSC2 3.8449 6.6732 2.0596 5.4916
COLO 824 GDSC1; GDSC2 3.9779 11.5604 -0.2643 16.646
MDA-MB-157 GDSC1; GDSC2; CTRP2 4.0484 6.5546 3.3559 9.2871
HCC2157 GDSC1; GDSC2 4.1674 6.8852 2.1862 4.2244
MDA-MB-436 GDSC1; GDSC2 4.3483 7.0123 2.2459 3.6166
MFM-223 GDSC1; GDSC2 4.3974 6.6406 2.4502 2.5527
YMB-1-E GDSC2 4.3991 8.454 1.5887 8.163
MDA-MB-468 GDSC1; GDSC2; CTRP2 4.4211 6.6979 3.6543 7.1689
OCUB-M GDSC1; GDSC2 4.6571 9.2275 1.3942 7.3218
BT-20 GDSC1; GDSC2; CTRP2 4.7116 6.7255 3.9125 5.4415
Hs 578T GDSC1; GDSC2; CTRP2 4.7216 5.9249 4.3128 3.7605
MDA-MB-330 GDSC1; GDSC2 4.7304 11.6807 0.2504 12.7059
Evsa-T GDSC1; GDSC2 4.7585 6.3713 2.7631 0.8104
MRK-nu-1 GDSC1; GDSC2 4.8076 6.3243 2.8045 0.6344
HCC1500 GDSC1; GDSC2; CTRP2 4.9189 6.758 4.0808 4.2992
HCC1395 GDSC1; GDSC2; CTRP2 4.9689 7.9463 2.8341 4.0487
HCC1954 GDSC1; GDSC2; CTRP2 4.9855 6.7507 4.1417 3.9094
MDA-MB-175-VII GDSC1; GDSC2 4.9993 7.2374 2.5222 1.7945
UACC-812 GDSC1; GDSC2; CTRP2 5.0062 7.0639 4.0026 4.4533
HCC1569 GDSC1; GDSC2; CTRP2 5.0467 7.856 3.6405 5.8963
ZR-75-30 GDSC1; GDSC2; CTRP2 5.0604 7.812 3.6739 5.7296
BT-549 GDSC1; GDSC2 5.0651 8.0503 2.2039 2.7776
BT-483 GDSC1; GDSC2 5.1832 8.6076 2.0218 4.1165
HCC1806 GDSC1; GDSC2; CTRP2 5.2802 7.9639 3.7762 4.8926
HCC1419 GDSC1; GDSC2; CTRP2 5.287 6.8215 4.3491 2.4865
SK-BR-3 CTRP2 5.2917 9.1819 3.178 7.3786
HCC1187 GDSC1; GDSC2 5.3009 12.1688 0.4194 10.8255
UACC-893 GDSC1; GDSC2 5.3089 10.731 1.1137 8.927
KPL-1 CTRP2 5.3801 6.936 4.3617 2.283
T-47D GDSC1; GDSC2; CTRP2 5.4035 9.5775 3.0697 7.6287
HCC2218 GDSC1; GDSC2; CTRP2 5.4949 7.8292 4.0073 3.5629
HCC1428 GDSC1; GDSC2; CTRP2 5.4961 7.1049 4.362 2.1049
Hs 578Bst CTRP2 5.6053 8.9985 3.5131 5.4311
BT-474 GDSC1; GDSC2; CTRP2 5.7023 7.6898 4.2216 2.3756
HDQ-P1 GDSC1; GDSC2; CTRP2 5.7092 13.3469 1.4333 13.6898
CAL-148 GDSC1; GDSC2; CTRP2 5.7268 7.7534 4.2077 2.3974
EFM-192A GDSC1; GDSC2; CTRP2 5.7319 15.0372 0.6088 16.6747
MDA-MB-415 GDSC1; GDSC2 5.8109 7.5612 2.7525 0.2864
ZR-75-1 CTRP2 5.8294 10.7661 2.8085 7.9747
HCC1937 GDSC1; GDSC2; CTRP2 5.9058 8.3512 4.042 2.812
HCC1143 GDSC2; CTRP2 5.9204 11.5967 2.4666 9.2212
CAMA-1 GDSC1; GDSC2; CTRP2 5.9338 8.0239 3.3622 0.9081
HCC70 GDSC1; GDSC2 5.9586 7.4572 2.842 0.1182
MDA-MB-231 GDSC1; GDSC2; CTRP2 6.1265 9.8936 3.4517 4.8712
HCC38 GDSC1; GDSC2; CTRP2 6.1539 8.2649 4.2379 1.7534
CAL-120 GDSC1; GDSC2; CTRP2 6.2038 8.0969 4.3417 1.3282
EFM-19 GDSC1; GDSC2 6.3456 11.767 1.2736 5.2617
CAL-51 GDSC1; GDSC2; CTRP2 6.5283 9.8742 3.7257 3.2481
CAL-85-1 GDSC1; GDSC2; CTRP2 6.9483 15.1671 1.4687 11.4601
JIMT-1 GDSC1; GDSC2; CTRP2 7.2535 12.2872 3.0567 4.9212
HMC-1-8 CTRP2 7.6177 16.8671 1.116 11.7305
MDA-MB-361 GDSC1; GDSC2; CTRP2 7.9445 13.8953 2.7388 5.2931
BT 239 CTRP2 0.6281 6.3379 -0.1816 32.0373
BT 416 CTRP2 1.0547 7.3076 -0.0844 30.3613
BT 482 CTRP2 1.6975 8.1531 0.2437 27.3671
BT 286 CTRP2 2.4336 9.8655 0.2196 25.3851
BT 271 CTRP2 2.5461 10.962 -0.188 26.3882
BT 131 CTRP2 2.8486 10.7217 0.2181 24.3056
BT 330 CTRP2 2.874 11.9519 -0.3509 26.0435
BT147 CTRP2 4.3837 12.0872 0.9583 18.1078
BT 231 CTRP2 4.3839 8.113 2.93 10.2478
BT 228 CTRP2 4.7235 10.3865 2.1014 12.9464
BT 159 CTRP2 4.9935 6.3907 4.3284 3.1094
BT 172 CTRP2 5.0228 13.5311 0.7831 17.4213
BT 216 CTRP2 5.0785 8.0376 3.5761 6.1063
BT164 CTRP2 5.212 6.7871 4.3085 2.7846
BT 139 CTRP2 5.3497 6.3692 4.616 1.2898
BT 179 CTRP2 5.3539 6.4113 4.5985 1.3542
BT 145 CTRP2 5.4094 6.8017 4.4482 1.8829
BT 112 CTRP2 5.4588 6.9814 4.3957 2.0232
BT 248 CTRP2 5.5655 9.0064 3.4792 5.6387
BT 245 CTRP2 5.5792 10.5792 2.7091 8.8147
BT 224 CTRP2 5.6351 6.8392 4.5785 1.0692
BT 428 CTRP2 5.7161 7.679 4.2361 2.2988
BT 328 CTRP2 5.8101 13.8856 1.2446 14.2213
BT 333 CTRP2 6.377 15.4105 0.9257 14.3949
BT 504 CTRP2 6.6103 16.4893 0.5688 15.257
BT 440 CTRP2 7.0181 13.682 2.2393 8.4073
BT 320 CTRP2 7.1517 15.4663 1.4681 11.1478
BT 232 CTRP2 7.3816 17.2597 0.7581 13.3504
BT 422 CTRP2 7.6093 18.6876 0.2243 14.8007
BT 444 CTRP2 8.0522 29.3192 -4.6865 26.1362
BT 340 CTRP2 8.5146 22.1806 -0.8322 16.6835
BT 359 CTRP2 9.5745 26.3826 -2.1257 18.6216
BT 498 CTRP2 9.7555 26.2153 -1.9185 17.863
⏷ Show the Full List of 90 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 4.8073 6.2738 3.52 1.3902
Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med GDSC1; GDSC2; CTRP2 2.3412 6.7236 1.5117 21.0299
PFSK-1 GDSC1; GDSC2 2.8546 8.3907 0.3883 16.4212
SNU-1105 CTRP2 3.1082 4.5452 0.6027 0.2571
D-502MG GDSC1; GDSC2 3.8977 5.7445 2.5504 3.4424
LN-405 GDSC1; GDSC2 4.2231 6.1903 2.5511 2.3309
D-336MG GDSC2 4.3087 13.8259 -1.1321 22.1228
AM-38 GDSC1; GDSC2 4.623 10.0107 0.9901 9.3894
H4 GDSC1; GDSC2 4.6485 6.6776 2.5781 1.6463
D-263MG GDSC1; GDSC2 4.6884 6.2972 2.7599 0.8802
M059J GDSC1; GDSC2 4.8078 7.0247 2.513 1.7411
GB-1 GDSC1; GDSC2; CTRP2 4.8355 10.9987 1.8914 13.5665
SNU-466 CTRP2 4.8953 7.2815 3.1032 3.0047
GI-1 GDSC1; GDSC2 4.9229 7.7848 2.2413 2.7932
D-392MG GDSC1; GDSC2 5.066 9.0939 1.7276 4.9945
SF539 GDSC1; GDSC2; CTRP2 5.1222 7.3829 3.9393 4.497
SF268 GDSC1; GDSC2; CTRP2 5.126 6.8386 4.2144 3.3346
Hs 683 GDSC1; GDSC2; CTRP2 5.1666 6.4523 4.4395 2.3162
SNU-489 CTRP2 5.2422 7.0734 4.1896 3.2289
D-247MG GDSC2 5.2835 7.2974 2.6342 1.023
Onda 10 GDSC1; GDSC2 5.3301 7.1913 2.6961 0.7591
U-118MG GDSC1; GDSC2; CTRP2 5.3461 7.6265 3.9953 3.8606
42-MG-BA GDSC1; GDSC2; CTRP2 5.3644 7.5174 4.0634 3.5455
SW1783 GDSC1; GDSC2; CTRP2 5.3932 7.613 4.0379 3.6033
MOG-G-CCM GDSC1; GDSC2 5.4184 7.9779 2.4219 1.7883
KG-1-C CTRP2 5.4601 6.6582 4.5521 1.3911
D-542MG GDSC1; GDSC2 5.4694 7.256 2.7298 0.5618
NMC-G1 GDSC1; GDSC2; CTRP2 5.4844 6.973 4.4176 1.8967
SNB-75 GDSC1; GDSC2; CTRP2 5.5033 7.4597 4.1946 2.7778
U-251MG GDSC1; GDSC2; CTRP2 5.5113 7.1006 4.3746 2.0316
SK-MG-1 GDSC1; GDSC2 5.5202 11.3774 0.9459 7.9897
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 5.5494 17.2879 -1.9028 19.5755
M059K CTRP2 5.5755 7.1252 4.4064 1.8131
Becker GDSC1; GDSC2; CTRP2 5.5798 7.1631 4.3912 1.868
LNZTA3WT4 GDSC1; GDSC2 5.5854 7.9176 2.5251 1.193
D-423MG GDSC1; GDSC2 5.5858 11.6592 0.8554 9.7999
YKG-1 GDSC1; GDSC2; CTRP2 5.5929 7.6433 4.1688 2.747
SNU-738 CTRP2 5.5955 7.1544 4.4058 1.7885
A-172 GDSC1; GDSC2; CTRP2 5.5982 7.7716 4.1102 2.9779
TM-31 CTRP2 5.6245 8.5055 3.7703 4.3344
SNU-201 CTRP2 5.6254 7.401 4.3081 2.137
MOG-G-UVW GDSC1; GDSC2 5.6304 7.6541 2.6467 0.7247
GMS-10 CTRP2 5.6439 7.2491 4.3927 1.7753
T98G GDSC1; GDSC2; CTRP2 5.649 8.0059 4.0323 3.2193
SNU-626 CTRP2 5.6974 7.7497 4.1896 2.5108
U-87MG ATCC GDSC1; GDSC2; CTRP2 5.7001 7.3049 3.5421 0.542
ONS-76 GDSC1; GDSC2; CTRP2 5.7248 8.4636 3.8634 3.7948
LN-18 GDSC1; GDSC2; CTRP2 5.7449 7.1308 3.6278 0.3131
DK-MG GDSC1; GDSC2; CTRP2 5.7498 7.7524 4.2235 2.3028
KNS-60 CTRP2 5.7695 6.9168 3.7152 0.1454
YH-13 GDSC1; GDSC2; CTRP2 5.8152 7.8762 4.2078 2.2772
D-566MG GDSC1; GDSC2 5.8202 7.4472 2.7961 0.2502
D-245MG GDSC2 5.8527 9.1965 2.1292 2.6471
CAS-1 GDSC1; GDSC2; CTRP2 5.9255 8.2937 4.0823 2.6262
GOS-3 CTRP2 5.9442 8.8962 3.807 3.6994
KNS-81-FD GDSC1; GDSC2 6.017 7.742 2.7652 0.2504
SW1088 GDSC1; GDSC2; CTRP2 6.0306 8.3938 4.1029 2.4098
SF126 GDSC1; GDSC2; CTRP2 6.0384 9.1123 3.7673 3.7254
Onda 11 GDSC1; GDSC2 6.1438 12.4995 0.8174 8.9381
KNS-81 CTRP2 6.298 7.5656 4.6126 0.4144
CCF-STTG1 CTRP2 6.4057 7.8069 4.5657 0.4749
DBTRG-05MG GDSC1; GDSC2; CTRP2 6.4675 10.4374 3.4218 4.5117
GaMG GDSC1; GDSC2; CTRP2; CTRP1 6.6728 11.2512 3.1824 5.2524
8-MG-BA GDSC1; GDSC2; CTRP2 6.8794 12.0769 2.9147 5.9552
SF295 GDSC1; GDSC2; CTRP2 6.9825 8.3587 4.5962 0.1849
KNS-42 GDSC1; GDSC2; CTRP2 7.403 14.5551 2.0821 8.4635
KALS-1 GDSC1; GDSC2; CTRP2 8.4429 14.5379 2.7415 4.7348
KINGS-1 GDSC1; GDSC2 8.6855 22.5166 -2.2581 15.4383
Daoy GDSC1; GDSC2; CTRP2 8.8925 17.3567 1.7231 7.8558
LN-229 GDSC1; GDSC2; CTRP2; CTRP1 9.0009 16.9087 2.0077 6.788
⏷ Show the Full List of 69 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1; GDSC2 2.6237 11.2979 -1.262 24.0687
TGBC1TKB GDSC1; GDSC2 4.673 6.8456 2.5179 2.2539
ETK-1 GDSC1; GDSC2 5.3197 13.3948 -0.1623 13.3831
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-251 CTRP2 4.1316 5.8587 1.4975 0.4579
JHUEM-1 CTRP2 4.577 5.6652 4.2919 4.1985
MFE-280 GDSC1; GDSC2 4.7803 7.2898 2.3812 2.348
RL95-2 GDSC2; CTRP2 4.8448 7.2072 3.7924 5.661
HEC-1-A CTRP2 4.9227 6.1491 4.3876 3.005
HEC-151 CTRP2; CTRP1 4.9376 6.4215 4.274 3.5376
EN GDSC1; GDSC2; CTRP2 5.0376 5.8219 4.65 1.671
JHUEM-7 CTRP2 5.0499 6.0071 4.5677 1.9932
HEC-6 CTRP2 5.0777 6.3253 2.6516 0.1216
KLE GDSC1; GDSC2; CTRP2; CTRP1 5.1504 10.1952 2.5666 10.2698
JHUEM-2 CTRP2; CTRP1 5.1848 8.0305 3.6766 5.5662
AN3-CA GDSC1; GDSC2; CTRP2 5.2041 8.4769 3.4594 6.3601
ESS-1 GDSC1; GDSC2; CTRP2 5.2352 6.4253 4.5058 1.9211
MFE-296 GDSC1; GDSC2; CTRP2 5.365 6.8883 4.374 2.2561
JHUEM-3 CTRP2 5.4076 7.2326 4.2363 2.7567
HEC-50B CTRP2 5.761 10.2797 2.9973 7.3104
HEC-108 CTRP2; CTRP1 5.9606 9.2245 3.6712 4.3009
HEC-265 CTRP2 6.0824 7.3511 4.5982 0.5897
MFE-319 GDSC1; GDSC2; CTRP2 6.1038 8.6751 4.0177 2.6479
HEC-1-B CTRP2 6.4544 8.1407 3.5381 0.2444
EFE-184 CTRP2 6.6634 8.3273 4.4761 0.5623
HEC-59 CTRP2; CTRP1 7.3886 12.0018 3.2832 3.978
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 10.2731 22.5994 0.1598 11.4246
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW13 GDSC1; GDSC2 3.7731 7.7823 1.4557 8.7846
KTCTL-13 GDSC2 3.8701 6.0166 2.3996 4.4257
KMRC-3 CTRP2 4.5306 6.9717 3.6249 7.0383
KTCTL-1M GDSC2 4.7062 7.0215 2.4586 2.5176
RXF 393L GDSC1; GDSC2 4.7231 12.1248 0.0266 13.7367
UO-31 GDSC1; GDSC2; CTRP2 4.8058 6.313 4.2018 4.0309
NCC021 GDSC2 4.9697 7.1201 2.5566 1.6729
KTCTL-21 GDSC2 4.9903 9.2882 1.5882 6.917
BB65-RCC GDSC1; GDSC2 5.1353 14.717 -0.944 19.3284
CAL-54 GDSC1; GDSC2; CTRP2 5.2428 9.9204 2.7697 9.1742
VMRC-RCZ GDSC1; GDSC2; CTRP2 5.2519 6.6904 4.3873 2.3865
KMRC-2 CTRP2 5.3339 7.329 4.1334 3.3055
SN12C GDSC1; GDSC2 5.3491 11.3601 0.8409 8.7747
KMRC-1 GDSC1; GDSC2; CTRP2 5.4226 6.5049 4.6002 1.2509
SW156 GDSC1; GDSC2 5.5465 10.1005 1.5582 6.0581
ACHN GDSC1; GDSC2; CTRP2 5.6037 8.6028 3.7071 4.6293
NCC010 GDSC2 5.6094 9.5011 1.8662 3.5899
TUHR4TKB CTRP2 5.7194 7.3498 4.3939 1.6728
A-704 GDSC1; GDSC2 5.8397 13.2854 0.25 10.6287
KTCTL-195 GDSC2 5.8538 9.2247 2.1179 2.2509
LB1047-RCC GDSC1; GDSC2 5.879 10.5229 1.5632 5.4788
KTCTL-26A GDSC2 5.8931 7.5074 2.8016 0.2194
Caki-2 CTRP2 5.9375 8.3709 4.0536 2.7233
OS-RC-2 GDSC1; GDSC2; CTRP2 6.0547 8.6863 3.9809 2.8549
KTCTL-140 GDSC2 6.0655 8.271 2.5941 0.6343
SNU-1272 CTRP2 6.1376 17.0489 -0.0729 18.2228
LB2241-RCC GDSC1; GDSC2 6.2565 8.3835 2.6278 0.4577
KMRC-20 GDSC1; GDSC2; CTRP2 6.2979 9.7384 3.6419 3.8692
BFTC-909 GDSC1; GDSC2; CTRP2 6.3908 9.8078 3.6695 3.638
Caki-1 GDSC1; GDSC2; CTRP2 6.5282 10.618 3.376 4.611
TUHR10TKB CTRP2 6.5896 7.8106 4.6422 0.2228
A-498 GDSC1; GDSC2 6.6101 16.7228 -0.8758 13.9516
HA7-RCC GDSC1; GDSC2 6.7642 14.4533 0.2965 8.9354
LB996-RCC GDSC1; GDSC2 6.8475 16.7762 -0.7426 13.0423
VMRC-RCW GDSC1; GDSC2; CTRP2 7.2425 8.7194 4.5658 0.167
786-O GDSC1; GDSC2; CTRP2 7.3574 13.3819 2.6097 6.5026
TK-10 GDSC1; GDSC2 7.4766 16.7352 -0.3195 10.4058
TUHR14TKB CTRP2 7.7474 9.7765 4.3799 0.321
RCC10RGB GDSC1; GDSC2; CTRP2 9.4148 18.5341 1.5002 8.0172
769-P GDSC1; GDSC2; CTRP2 10.2911 19.7384 1.4722 7.152
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 62 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 320 CTRP2; CTRP1 0.5116 7.4647 -0.7189 34.0011
LS513 GDSC1; GDSC2; CTRP2 1.8058 5.9 1.2442 23.5649
SNU-C1 GDSC1; GDSC2; CTRP2 1.8801 4.527 1.7174 21.641
SW48 GDSC1; GDSC2; CTRP2 1.895 7.0946 0.8909 24.574
COLO 320HSR GDSC1; GDSC2 1.9031 8.666 -0.6084 23.6147
HT-55 GDSC1; GDSC2; CTRP2; CTRP1 2.2407 8.126 0.822 23.9101
COLO205 GDSC1; GDSC2; CTRP2 2.3341 8.5061 0.7429 23.8644
NCI-H716 GDSC1; GDSC2; CTRP2 2.5867 5.7945 2.1255 18.0289
SK-CO-1 GDSC2; CTRP2 3.3931 8.2263 1.9308 16.6337
SNU-283 GDSC2 3.5095 8.1721 1.0513 13.6629
CCK-81 GDSC1; GDSC2; CTRP2 3.6335 10.0319 1.2954 18.5301
SNU-1033 CTRP2 3.9633 11.8032 0.7265 19.8756
LS1034 GDSC1; GDSC2; CTRP2 4.0568 8.7571 2.3121 13.5242
C2BBe1 GDSC1; GDSC2; CTRP2 4.1801 9.2433 2.1873 13.7558
HCT 15 GDSC1; GDSC2; CTRP2 4.1877 6.7364 3.4097 8.7257
SNU-175 GDSC2; CTRP1 4.2055 14.4718 -0.3763 24.779
GP2d CTRP2 4.298 7.2107 3.2901 8.9529
HT115 GDSC1; GDSC2; CTRP2; CTRP1 4.4097 8.1626 2.9376 10.2418
T84 GDSC1; GDSC2; CTRP2 4.4176 7.1018 3.4559 7.994
CL-34 CTRP1 4.5245 10.5235 1.8694 27.547
SW1116 GDSC2 4.5298 9.5406 1.1527 8.7654
LS411N GDSC1; GDSC2; CTRP2 4.5535 8.8584 2.7143 10.7771
SW1463 GDSC1; GDSC2 4.6145 9.5054 1.23 8.2189
SW948 GDSC1; GDSC2; CTRP2; CTRP1 4.6801 8.1743 3.1752 8.6711
CaR-1 GDSC1; GDSC2 4.6802 8.8214 1.6052 6.2304
DiFi GDSC2 4.8435 12.7505 -0.1922 14.4551
LS180 GDSC1; GDSC2; CTRP2; CTRP1 4.9086 6.1496 4.3837 3.139
OUMS-23 CTRP2 5.0992 6.6743 4.2746 3.1316
CW-2 GDSC1; GDSC2; CTRP2; CTRP1 5.1184 8.8349 3.2202 7.6055
SNU-407 GDSC2; CTRP2 5.1205 10.6072 2.3261 11.2405
NCI-H508 GDSC2; CTRP2; CTRP1 5.2246 11.5112 1.9697 12.5625
CL-40 CTRP1 5.2656 9.2093 3.1533 15.8803
HCC-56 CTRP2 5.2734 7.085 4.2081 3.0972
SNU-C4 CTRP2; CTRP1 5.3139 8.3772 3.6072 5.6218
COLO201 CTRP2 5.3515 7.5211 4.0517 3.616
SNU-C2A CTRP2 5.395 9.4113 3.1458 7.3263
SW626 GDSC1; GDSC2 5.6493 12.0796 0.6977 8.9286
GP5d GDSC1; GDSC2 5.8735 11.9586 0.8997 7.6327
NCI-H747 GDSC1; GDSC2; CTRP2 5.8899 16.3113 0.0991 18.1141
HCC2998 GDSC1; GDSC2 6.0662 13.9331 0.0922 10.9316
COLO 678 GDSC1; GDSC2; CTRP2; CTRP1 6.1358 10.7126 3.0715 6.4777
SNU-61 GDSC2; CTRP2; CTRP1 6.1419 11.1435 2.8651 7.3095
MDST8 GDSC1; GDSC2; CTRP2; CTRP1 6.2744 10.8906 3.0834 6.2181
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2; CTRP1 6.298 12.3023 2.4108 8.8995
DLD-1 CTRP2 6.3166 7.3214 4.7135 0.183
KM12 GDSC1; GDSC2; CTRP2; CTRP1 6.3576 9.2855 3.9049 2.8394
SW837 GDSC1; GDSC2 6.3607 13.4894 0.4924 8.7028
LoVo GDSC1; GDSC2; CTRP2; CTRP1 6.4529 12.6426 2.3567 8.8701
CL-11 GDSC1; GDSC2; CTRP2 6.6876 15.5644 1.0831 13.3024
SNU-81 GDSC2; CTRP1 6.6899 8.0811 4.5964 0.3387
HCT 8 CTRP2; CTRP1 6.7338 8.0714 4.6178 0.2507
SNU-503 CTRP2 7.4056 13.765 2.46 7.0141
SW1417 GDSC1; GDSC2; CTRP2 7.4124 15.1804 1.7883 9.5624
SW480 CTRP1 7.4895 16.5116 1.21 20.208
SNU-C2B GDSC1; GDSC2 7.7777 17.9377 -0.6905 11.3964
SNU-C5 GDSC2; CTRP2; CTRP1 7.9316 13.8444 2.7667 5.2702
SNU-1040 GDSC2; CTRP1 8.1191 15.1512 2.2779 7.473
RKO GDSC1; GDSC2; CTRP2; CTRP1 8.439 16.8883 1.6681 8.6753
LS123 GDSC1; GDSC2; CTRP2; CTRP1 9.432 18.1581 1.6953 7.3885
SW620 GDSC1; GDSC2; CTRP2; CTRP1 10.415 22.6541 0.2235 11.0596
HCT 116 GDSC1; GDSC2; CTRP2; CTRP1 10.5561 19.2557 1.849 5.7218
HT-29 GDSC1; GDSC2; CTRP2; CTRP1 11.71 28.2756 -1.585 14.625
⏷ Show the Full List of 62 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 4.0559 6.0332 2.5183 2.7549
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-475 GDSC1 3.3396 4.5563 0.9647 0.1899
SNU-182 CTRP2 3.4196 9.2226 1.484 18.3177
HuH-6 CTRP2 3.7948 8.8974 1.9981 15.3985
Li-7 CTRP2 4.1028 9.5878 1.9471 14.899
JHH-5 CTRP2 4.3275 9.2733 2.3063 12.9459
SNU-761 CTRP2 4.3506 7.1207 2.7842 5.3308
SNU-878 CTRP2 4.4155 8.2378 2.8975 10.3131
HuH-1 GDSC1; GDSC2; CTRP2 4.4342 9.3547 2.3618 12.4877
Hep-G2/C3A GDSC1; GDSC2 4.5297 6.8982 2.4119 2.5432
SNU-387 GDSC1; GDSC2; CTRP2 4.6554 13.7166 0.38 19.5883
HLE GDSC1; GDSC2 4.67 7.7548 2.1029 3.802
JHH-7 GDSC1; GDSC2 4.774 8.9813 1.5917 6.1343
SNU-423 GDSC1; GDSC2; CTRP2 5.1675 7.3672 3.9839 4.2255
SNU-398 GDSC1; GDSC2; CTRP2; CTRP1 5.3264 8.6331 3.4895 6.092
JHH-2 GDSC1; GDSC2; CTRP2 5.3477 7.1498 4.2325 2.8699
JHH-1 GDSC1; GDSC2; CTRP2 5.3814 6.8056 4.4264 2.0147
SK-HEP-1 GDSC1; GDSC2; CTRP2 5.4306 6.8928 4.4189 1.9706
Huh-7 GDSC1; GDSC2 5.4889 12.5169 0.381 10.659
PLC/PRF/5 CTRP2 5.598 7.5179 4.2331 2.4782
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 5.6056 9.7917 3.1207 7.0618
HLF CTRP2 5.7059 7.9593 4.0946 2.8818
JHH-6 GDSC1; GDSC2; CTRP2; CTRP1 6.1978 7.1186 4.7548 0.1783
SNU-886 CTRP2 7.0619 8.734 4.4905 0.3457
Hep-G2 CTRP2; CTRP1 7.3122 14.8573 1.8867 9.4033
SNU-449 GDSC1; GDSC2; CTRP2; CTRP1 7.9277 18.9825 0.3188 14.0646
JHH-4 GDSC1; GDSC2; CTRP2 7.9498 17.2551 1.1578 11.0994
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 225 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1588 CTRP2 0.9744 5.3698 0.5097 28.6965
COR-L32 GDSC2 0.9901 5.5189 -0.036 28.6796
NCI-H1770 GDSC1; GDSC2 1.1555 6.7399 -0.4119 29.6372
NCI-H847 GDSC1; GDSC2 1.2376 6.3974 -0.173 28.2313
NCI-H2171 GDSC1; GDSC2 1.5778 5.6247 0.5201 23.3481
LC-2/ad GDSC1; GDSC2 1.5805 14.2243 -3.6408 37.0216
NCI-H1623 GDSC1; GDSC2; CTRP2 1.6567 5.8384 1.1036 24.5169
COR-L303 GDSC2 1.6749 8.4211 -0.7033 28.7293
NCI-H1304 GDSC1 1.7175 4.5659 0.0416 9.1045
Lu-134-A GDSC1; GDSC2 1.8539 7.7745 -0.2211 25.9675
NCI-H1341 GDSC2; CTRP2 2.0057 5.0268 1.733 21.1958
HCC827 GDSC1; GDSC2; CTRP2; CTRP1 2.2245 4.5134 2.0957 19.3067
NCI-H187 GDSC1 2.266 5.4098 0.0283 7.5643
NCI-H727 GDSC1; GDSC2; CTRP2 2.3999 6.9323 1.4893 20.9492
CPC-N GDSC1; GDSC2 2.4791 9.9638 -0.7251 22.406
COR-L311 GDSC2 2.5096 5.9558 1.279 12.9046
NCI-H2073 CTRP1 2.8919 18.0161 -3.3038 45.274
LB647-SCLC GDSC1; GDSC2 2.9097 10.3711 -0.5518 23.7643
NCI-H3255 GDSC1; GDSC2; CTRP1 3.0206 5.6408 2.6521 16.3235
NCI-H2122 GDSC1; GDSC2; CTRP2; CTRP1 3.1796 7.5668 2.0279 16.8677
COLO 668 GDSC1; GDSC2; CTRP2; CTRP1 3.185 8.6477 1.5358 18.7709
Ms-1 GDSC1; GDSC2 3.1929 10.3246 -0.2875 18.6492
NCI-H1105 GDSC2; CTRP2; CTRP1 3.1989 7.4662 2.0926 16.5638
NCI-H358 GDSC1; GDSC2; CTRP2 3.2751 10.2155 0.8686 20.9791
NCI-H211 GDSC1; GDSC2; CTRP2 3.3545 8.9128 1.5691 18.1472
NCI-H2106 CTRP2 3.3548 8.0857 1.9587 16.6185
NCI-H1648 GDSC1; GDSC2 3.4187 10.5967 -0.2351 20.7668
IST-SL2 GDSC1; GDSC2 3.4694 7.597 1.306 10.2537
LCLC-97TM1 GDSC1; GDSC2; CTRP2 3.4938 13.5821 -0.5768 25.2126
COR-L95 GDSC1; GDSC2; CTRP2 3.5854 8.0217 2.2155 15.0266
NCI-H526 GDSC1; GDSC2; CTRP2 3.5988 12.6769 -0.0346 23.2998
NCI-H2141 GDSC1; GDSC2; CTRP2; CTRP1 3.6583 8.1473 2.2344 14.8526
DMS 53 GDSC1; GDSC2; CTRP2 3.6756 6.4749 3.0124 11.6124
NCI-H82 GDSC1; GDSC2 3.7448 6.6129 2.0142 5.9362
IST-SL1 GDSC1; GDSC2 3.762 6.0746 2.2929 5.3414
NCI-H345 GDSC1; GDSC2 3.7935 5.9417 2.3812 3.9286
NCI-H1581 GDSC1; GDSC2; CTRP2 3.8434 5.9321 3.4174 9.5782
NCI-H1437 GDSC1; GDSC2 3.9135 11.5272 -0.2988 19.6456
NCI-H810 GDSC1; GDSC2; CTRP2 3.922 6.1421 3.4108 9.3934
NCI-H524 GDSC1; GDSC2 3.9269 7.7619 1.5838 7.7902
NCI-H835 GDSC2 3.9385 11.4994 -0.265 19.4213
A-427 GDSC1; GDSC2 3.9585 10.619 0.1894 14.6468
NCI-H292 GDSC1; GDSC2; CTRP2 3.9851 11.0227 1.1322 18.3379
NCI-H2227 GDSC1; GDSC2 4.0113 5.8698 2.5665 2.5906
COR-L279 GDSC2 4.0193 11.0323 0.0314 17.7784
Lu-135 GDSC1; GDSC2 4.0825 8.176 1.4959 7.9197
DMS 454 CTRP2 4.1037 8.2057 2.6247 12.1383
SK-MES-1 GDSC1; GDSC2; CTRP2 4.1064 5.8459 3.7286 7.6563
DV-90 CTRP2 4.1616 6.396 3.5418 8.2558
NCI-H1944 GDSC1; GDSC2; CTRP2 4.1832 6.5305 3.5014 8.3648
COR-L88 GDSC1; GDSC2; CTRP2 4.1875 6.3711 3.5791 8.0407
LUDLU-1 CTRP2 4.1896 7.5402 3.0281 10.2824
NCI-H1688 GDSC1; GDSC2 4.2169 8.7948 1.2908 10.3659
Lu-139 GDSC1; GDSC2 4.2398 6.6846 2.3302 3.3798
NCI-H720 GDSC1; GDSC2 4.244 6.1434 2.5855 2.1369
ChaGo-K-1 GDSC1; GDSC2; CTRP2 4.2555 7.058 3.3229 8.9175
NCI-H1734 GDSC1; GDSC2; CTRP2 4.2585 6.7165 3.4883 8.2347
RERF-LC-MS GDSC1; GDSC2; CTRP2 4.2608 5.7828 3.9159 6.5108
NCI-H1568 GDSC1; GDSC2; CTRP2 4.3052 7.2539 3.2761 8.9944
NCI-H2066 GDSC2 4.3133 9.7525 0.8908 12.4442
NCI-H2029 GDSC1; GDSC2; CTRP2 4.3219 6.4791 3.6621 7.3736
Lu-99 CTRP2 4.3222 7.1708 3.3323 8.7232
NCI-H1963 GDSC1; GDSC2; CTRP1 4.3233 8.2465 2.8171 11.9821
NCI-H748 GDSC1; GDSC2 4.3239 6.744 2.3564 3.739
IA-LM GDSC1; GDSC2 4.3646 6.374 2.5524 2.1209
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2 4.3814 7.4024 3.2757 8.8213
NCI-H250 GDSC2 4.3818 7.0996 2.2265 3.6573
NCI-H64 GDSC1; GDSC2 4.4045 7.6226 1.9931 5.7292
NCI-H2804 GDSC1; GDSC2 4.414 7.7889 1.9199 5.1267
NCI-H146 GDSC2 4.4194 7.1094 2.246 4.2028
NCI-H2731 GDSC1; GDSC2 4.452 11.9779 -0.1041 14.8888
NCI-H1703 GDSC1; GDSC2; CTRP2 4.4999 6.8992 3.6316 7.0801
NCI-H2818 GDSC1; GDSC2 4.5292 9.5534 1.146 8.7997
UMC-11 GDSC1; GDSC2 4.5362 6.5806 2.5587 1.8655
NCI-H1563 GDSC1; GDSC2; CTRP2 4.5456 8.0123 3.1267 9.0772
COR-L321 GDSC2 4.5554 7.563 2.1201 4.6779
NCI-H2009 GDSC1; GDSC2; CTRP2 4.5683 11.2864 1.5183 15.592
NCI-H1092 GDSC1; GDSC2; CTRP2 4.5768 9.7805 2.2762 12.5369
NCI-H2810 GDSC2 4.6061 10.5283 0.7248 10.7169
NCI-H2135 GDSC1; GDSC2 4.6279 6.7109 2.5522 1.7818
NCI-H841 GDSC1; GDSC2; CTRP2; CTRP1 4.6286 9.5291 2.4558 11.769
NCI-H1436 GDSC1; GDSC2 4.6578 6.355 2.7209 1.2655
NCI-H1836 GDSC1; GDSC2; CTRP1 4.6798 8.595 2.9658 12.2331
DMS 273 GDSC1; GDSC2; CTRP2 4.6951 6.5012 4.0077 5.0822
NCI-H838 GDSC1; GDSC2; CTRP2 4.6967 8.4286 3.0544 9.0589
HCC4006 CTRP2; CTRP1 4.7207 8.0537 3.2711 8.1857
NCI-H2342 GDSC1; GDSC2; CTRP2; CTRP1 4.7441 9.0852 2.7778 10.1961
HCC2279 CTRP2 4.7603 7.1903 3.7263 6.1142
Lu-165 GDSC1; GDSC2 4.7831 10.1239 1.0483 8.7986
NCI-H2795 GDSC1; GDSC2 4.7886 13.802 -0.7517 16.9069
HCC2935 CTRP2; CTRP1 4.8322 6.9861 3.9004 5.3204
RERF-LC-Ad2 CTRP2 4.8498 7.0582 3.8711 5.3206
NCI-H1993 GDSC1; GDSC2 4.8523 10.8788 0.7304 10.2083
SHP-77 GDSC1; GDSC2; CTRP2 4.8539 7.958 3.4259 7.1797
PC-14 GDSC1; GDSC2; CTRP2 4.8622 6.7621 4.0293 4.6318
NCI-H1694 GDSC1; GDSC2; CTRP2; CTRP1 4.8842 8.2466 3.3172 7.6572
HCC33 GDSC1; GDSC2 4.8843 14.371 -0.9608 19.996
NCI-H446 GDSC1; GDSC2; CTRP2 4.8869 7.0465 3.9092 5.0846
NCI-H510A GDSC1; GDSC2 4.8913 6.929 2.5974 1.5726
SBC-3 GDSC1; GDSC2 4.8919 14.6335 -1.0847 17.9917
NCI-H2196 GDSC1; GDSC2; CTRP2 4.8947 6.0431 4.4154 2.9479
NCI-H513 GDSC1; GDSC2 4.9125 8.1508 2.0691 3.6022
NCI-H2373 GDSC1; GDSC2 4.9126 17.5214 -2.4997 22.7379
NCI-H1573 GDSC1; GDSC2; CTRP2 4.9208 8.7654 3.0799 8.4966
NCI-H69 GDSC1; GDSC2; CTRP2 4.9264 7.5565 3.6887 5.9302
VMRC-LCD GDSC2; CTRP2 4.9266 6.7918 4.0707 4.3258
NCI-H1373 CTRP2 4.9541 7.1428 3.919 4.9076
NCI-H1048 GDSC1; GDSC2 4.9575 7.1947 2.5189 1.5557
NCI-H1395 CTRP2 4.9619 9.3553 2.8198 9.5035
LK2 CTRP2 4.968 5.5401 4.7303 1.4754
EBC-1 GDSC1; GDSC2; CTRP2 4.9741 7.1237 3.9456 4.7559
NCI-H2591 GDSC1; GDSC2 4.975 8.3989 1.9931 3.8692
NCI-H1155 GDSC1; GDSC2; CTRP2 4.9803 6.8989 4.0632 4.2498
COLO 699 CTRP2; CTRP1 5.0056 13.1245 0.9816 16.8007
HCC1438 CTRP2 5.0071 5.8671 4.6015 1.9348
NCI-H3122 GDSC1; GDSC2 5.0295 8.8092 1.8371 4.5274
NCI-H2081 GDSC1; GDSC2; CTRP2; CTRP1 5.0415 9.7315 2.708 9.893
NCI-H23 GDSC1; GDSC2; CTRP2 5.045 7.9513 3.5915 6.1057
NCI-H2291 GDSC1; GDSC2; CTRP2 5.0524 7.9851 2.8723 3.7574
NCI-H322M GDSC1; GDSC2 5.0632 13.3988 -0.3493 14.6846
NCI-H2461 GDSC1; GDSC2 5.0939 11.677 0.5132 10.777
RERF-LC-Sq1 GDSC1; GDSC2 5.1024 8.5336 2.0079 3.6191
HCC1833 CTRP2; CTRP1 5.1053 12.3431 1.4554 14.8182
NCI-H1975 GDSC1; GDSC2 5.1096 13.2928 -0.2635 14.2274
NCI-H1838 GDSC1; GDSC2; CTRP2 5.1261 10.0937 2.5875 10.1514
NCI-H2085 GDSC1; GDSC2; CTRP2 5.1445 8.6874 3.3056 7.1169
NCI-H647 GDSC1; GDSC2; CTRP2 5.1641 6.8729 4.2278 3.2081
Lu-99A GDSC1; GDSC2 5.168 17.0879 -2.0897 20.9439
CAL-12T GDSC1; GDSC2; CTRP2; CTRP1 5.1839 10.5025 2.4406 10.7255
LOU-NH91 GDSC1; GDSC2; CTRP2 5.2202 11.1749 2.1244 11.8723
DMS 114 GDSC1; GDSC2; CTRP2 5.2389 8.8371 3.3076 6.9326
SW1271 GDSC1; GDSC2; CTRP2 5.2463 7.6446 3.9085 4.3989
NCI-H2722 GDSC1; GDSC2 5.2525 11.6267 0.6475 9.8557
RERF-LC-A1 CTRP2 5.2688 8.0245 3.7369 5.0777
MOR/CPR CTRP2 5.2711 6.3382 4.5754 1.5747
NCI-H2126 CTRP2 5.2911 7.4418 4.0446 3.75
Calu-3 GDSC1; GDSC2; CTRP2 5.296 7.7404 3.8999 4.3465
EPLC-272H GDSC1; GDSC2; CTRP2 5.3135 11.1677 2.204 11.3724
NCI-H1651 GDSC1; GDSC2; CTRP2 5.3367 8.0094 3.7979 4.7018
SBC-1 GDSC1; GDSC2 5.341 9.1554 1.8666 4.7197
NCI-H520 GDSC1; GDSC2; CTRP2 5.3508 7.0232 4.2973 2.5964
NCI-H1339 CTRP2 5.3937 6.7248 4.4745 1.7994
NCI-H1693 GDSC1; GDSC2; CTRP2 5.3965 10.1461 2.7807 8.8451
NCI-H889 CTRP2 5.3975 7.3436 4.1742 3.0303
NCI-H209 GDSC1; GDSC2 5.4028 12.2082 0.4706 10.4047
NCI-H290 GDSC1; GDSC2 5.4183 7.217 2.7235 0.6113
NCI-H1355 GDSC1; GDSC2; CTRP2 5.4338 14.6606 0.5568 17.4191
NCI-H2347 GDSC1; GDSC2 5.46 13.077 0.0909 13.9693
NCI-H2286 CTRP2; CTRP1 5.4798 7.413 4.2115 2.8241
HCC366 GDSC2; CTRP2 5.4976 11.4426 2.2147 10.9887
HOP-62 GDSC1; GDSC2; CTRP2 5.4996 7.5789 4.1336 3.0342
NCI-H1781 GDSC1; GDSC2; CTRP1 5.5532 9.9056 3.0341 8.318
NCI-H1930 CTRP1 5.5717 16.7659 -0.373 31.8772
LC-1/sq-SF CTRP2 5.5736 7.1407 4.3977 1.8507
Lu-65 GDSC1; GDSC2; CTRP2 5.574 9.6282 3.1775 6.8797
LXF 289 GDSC1; GDSC2; CTRP2; CTRP1 5.5862 10.3337 2.847 8.3091
NCI-H661 GDSC1; GDSC2; CTRP2 5.5912 9.7849 3.113 7.1184
NCI-H1793 GDSC1; GDSC2; CTRP2 5.6038 9.9671 3.0322 7.4326
HCC95 CTRP2 5.6233 8.7944 3.6272 4.9284
HOP-92 GDSC1; GDSC2; CTRP2 5.6317 10.6949 2.6925 8.7913
NCI-H2170 GDSC1; GDSC2; CTRP2 5.6632 7.9172 4.0853 2.9822
HCC1359 CTRP1 5.6674 7.282 4.4044 3.8047
NCI-H522 GDSC1; GDSC2; CTRP2 5.6691 10.764 2.6871 8.7483
NCI-H2110 GDSC1; GDSC2; CTRP2; CTRP1 5.6816 12.7063 1.7409 12.6191
Calu-1 CTRP2 5.6823 7.5181 4.2903 2.1293
NCI-H322 CTRP2 5.7064 8.6068 3.7803 4.1639
NCI-H2023 GDSC1; GDSC2; CTRP2; CTRP1 5.7172 7.6984 4.2393 2.3601
LC-1/sq GDSC1; GDSC2 5.7327 12.2081 0.6915 8.8171
EKVX GDSC1; GDSC2; CTRP2 5.7528 11.6031 2.3351 10.0437
NCI-H2405 GDSC1; GDSC2; CTRP2 5.7627 10.9805 2.6517 8.7323
NCI-H596 GDSC1; GDSC2; CTRP1 5.785 11.4854 2.4289 10.5865
HCC2108 CTRP2; CTRP1 5.8088 11.7698 2.3061 10.1386
PaCa-3 GDSC1; GDSC2 5.8187 10.9091 1.352 6.7029
ABC-1 GDSC1; GDSC2 5.8357 15.2875 -0.7174 14.7082
NCI-H740 GDSC2 5.8394 8.0208 2.5952 0.7594
BEN GDSC1; GDSC2; CTRP2 5.8474 7.233 4.5247 1.0368
DMS 79 GDSC1; GDSC2; CTRP2 5.8834 8.7178 3.8511 3.609
HCC15 GDSC1; GDSC2; CTRP2; CTRP1 5.8993 12.0996 2.2121 10.3611
NCI-H1915 GDSC1; GDSC2; CTRP2; CTRP1 5.904 8.8347 3.8205 3.7791
NCI-H196 GDSC1; GDSC2; CTRP2 5.9051 8.2814 4.0747 2.6833
NCI-H2803 GDSC1; GDSC2 5.9114 14.0322 -0.0591 11.8513
EMC-BAC-2 GDSC2 5.9248 14.3722 -0.2133 12.4834
NCI-H1184 CTRP2 5.9309 10.1807 3.1723 6.3108
Calu-6 GDSC1; GDSC2; CTRP2 5.9526 12.5356 2.0262 10.9402
KNS-62 GDSC2; CTRP2 5.9597 8.543 3.9865 2.9591
NCI-H1869 GDSC1; GDSC2; CTRP2 5.9764 10.5155 3.0413 6.7763
SK-LU-1 GDSC1; GDSC2; CTRP2; CTRP1 5.9867 10.355 3.1387 6.4367
NCI-H2087 GDSC1; GDSC2; CTRP2 5.993 11.4643 2.5867 8.6107
EMC-BAC-1 GDSC2 6.0009 8.8958 2.3252 1.6255
Sq-1 CTRP2; CTRP1 6.0373 8.3444 4.1423 2.3208
HCC1195 CTRP2; CTRP1 6.0432 9.5551 3.5688 4.5943
NCI-H1650 GDSC1; GDSC2; CTRP2 6.0653 10.3917 3.1664 6.1243
NCI-H2444 GDSC1; GDSC2; CTRP2 6.0753 7.2336 4.6429 0.4648
COR-L51 CTRP1 6.0811 7.9375 4.3558 2.7562
T3M-10 CTRP2; CTRP1 6.0868 12.5696 2.122 10.4023
NCI-H1435 GDSC1; GDSC2; CTRP2; CTRP1 6.1038 11.8902 2.4702 8.9753
RERF-LC-Ad1 CTRP2 6.1772 7.0843 4.7452 0.1715
SBC-5 GDSC1; GDSC2; CTRP2 6.2398 7.3761 4.6609 0.3255
HCC44 GDSC1; GDSC2; CTRP2 6.2422 14.0712 1.4862 12.548
SCLC-21H CTRP1 6.3381 12.6688 2.2602 16.439
NCI-H2172 GDSC1; GDSC2; CTRP2; CTRP1 6.3843 14.0719 1.6036 11.9291
NCI-H2228 GDSC1; GDSC2; CTRP2 6.3858 16.0869 0.5973 15.5425
RERF-LC-KJ GDSC1; GDSC2; CTRP1 6.4399 12.1627 2.5817 8.7388
NCI-H1876 GDSC1; GDSC2; CTRP1 6.4509 14.8552 1.2669 14.1951
A-549 GDSC1; GDSC2; CTRP2 6.5138 13.111 2.1604 9.4811
NCI-H650 GDSC1; GDSC2; CTRP2 6.6142 14.2993 0.9029 9.6343
COR-L23 GDSC1; GDSC2; CTRP1 6.6989 13.5808 2.0754 10.4644
NCI-H2369 GDSC1; GDSC2 6.8136 13.8432 0.6078 7.5283
NCI-H441 GDSC1; GDSC2; CTRP2; CTRP1 6.9026 16.5602 0.7631 14.1573
SW1573 GDSC1; GDSC2; CTRP2 7.0053 18.022 0.1085 16.1432
NCI-H1792 GDSC1; GDSC2; CTRP2 7.0079 12.2359 2.9238 5.7469
HCC1171 CTRP2 7.0175 13.5649 2.2953 8.1902
NCI-H2869 GDSC1; GDSC2 7.1261 18.8697 -1.5556 15.5586
NCI-H2595 GDSC1; GDSC2 7.1499 14.3703 0.5679 7.2332
NCI-H1666 GDSC1; GDSC2; CTRP2 7.4362 15.383 1.7071 9.8328
NCI-H460 GDSC1; GDSC2; CTRP2; CTRP1 7.7007 12.5256 3.2296 3.8329
NCI-H2030 GDSC1; GDSC2; CTRP2; CTRP1 8.0108 15.8861 1.8634 8.5221
COR-L105 GDSC1; GDSC2; CTRP2 8.2789 21.4812 -0.6592 16.5284
NCI-H1755 GDSC1; GDSC2; CTRP2; CTRP1 8.3365 17.3778 1.3701 9.8742
LCLC-103H GDSC1; GDSC2; CTRP2 8.657 17.6571 1.4346 9.165
LK-2 GDSC1; GDSC2 8.9056 21.6211 -1.6986 13.3377
NCI-H226 GDSC1; GDSC2; CTRP2 9.0809 19.5373 0.8226 10.7254
HCC78 GDSC1; GDSC2; CTRP2 9.4224 18.5223 1.5103 7.974
NCI-H1299 GDSC1; GDSC2; CTRP2 10.9314 20.3304 1.5707 6.2024
Hs 888.Lu CTRP2 5.0025 6.6251 4.2189 3.5514
⏷ Show the Full List of 225 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 3.7958 5.4525 2.621 2.6939
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 5.1505 7.8315 3.7382 5.2889
P-STS CTRP2 5.2246 6.61 4.4062 2.3542
SYO-1 CTRP2 10.5953 26.3485 -1.4125 15.4709
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 5.2856 6.6687 4.4235 2.1796
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 5.4229 7.4666 4.1324 3.1619
Aska-SS CTRP2 11.1884 28.1828 -1.8922 15.9725
Rh41 GDSC1; GDSC2; CTRP2 -1.6445 1.3149 -1.6631 44.6058
Tm87-16 CTRP2 1.4352 10.6116 -1.1177 32.0705
Rh30 GDSC1; GDSC2 2.1063 7.719 0.0431 20.1617
TE 441.T GDSC1; GDSC2; CTRP2 2.1812 8.5062 0.5872 24.8308
G-401 GDSC1; GDSC2; CTRP2 3.3974 11.1047 0.5519 21.8109
EW-8 GDSC1; GDSC2 3.7115 8.9819 0.8097 12.218
TE 617.T CTRP2 4.3291 5.7832 3.9863 6.0538
A-204 GDSC1; GDSC2; CTRP2 4.5163 8.6646 2.7773 10.5944
SW684 GDSC1; GDSC2 4.9074 6.5491 2.7606 0.7066
Hs 729.T CTRP2 4.9345 7.7667 3.5906 6.3261
GCT GDSC1; GDSC2; CTRP2 5.0046 6.3182 4.374 2.8956
G-402 GDSC1; GDSC2; CTRP2 5.0513 8.8971 3.1238 8.0574
RD GDSC1; GDSC2; CTRP2 5.0608 12.6803 1.2401 15.6579
HT-1080 GDSC1; GDSC2; CTRP2; CTRP1 5.2028 7.0681 4.1716 3.4577
MES-SA GDSC1; GDSC2; CTRP2 5.2312 6.529 4.4514 2.1544
BT-16 CTRP2 5.2445 7.2801 4.0886 3.6473
SK-LMS-1 GDSC1; GDSC2; CTRP2 5.2784 7.4642 4.0236 3.8599
KYM-1 GDSC1; GDSC2; CTRP2 5.3407 6.711 4.4432 2.0094
BT-12 CTRP2 5.4326 6.9014 4.4162 1.9788
Rh18 CTRP2 5.5936 15.1509 0.4412 17.5157
SK-UT-1 GDSC1; GDSC2; CTRP2 5.9192 8.058 4.1893 2.2149
RKN GDSC1; GDSC2; CTRP2; CTRP1 5.9253 8.0464 4.2107 2.1966
TTC-709 CTRP2 6.0254 11.4719 2.6071 8.4741
STS-0421 GDSC1; GDSC2 6.3732 15.7368 -0.5636 15.0455
MFH-ino GDSC1; GDSC2 6.559 14.9819 -0.0814 12.5439
Hs 633.T GDSC1; GDSC2 7.5797 17.3187 -0.5264 12.6497
SW872 GDSC1; GDSC2 7.8181 16.9025 -0.1878 9.3985
VA-ES-BJ GDSC1; GDSC2 8.0069 17.4756 -0.3365 9.7168
SW982 GDSC1; GDSC2; CTRP2 10.6106 25.3204 -0.9147 14.1047
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 8.4904 26.6863 -3.0562 22.3067
COV434 CTRP2; CTRP1 4.1626 8.4942 2.547 12.4036
JHOS-4 GDSC2; CTRP1 4.4007 10.5822 1.7312 19.171
SNU-119 CTRP2 4.4898 6.1361 3.9879 5.6417
DOV13 GDSC2; CTRP2 4.6553 6.1304 4.1508 4.5812
OC 314 GDSC1; GDSC2; CTRP2 4.8962 5.814 4.53 2.4663
JHOS-2 GDSC2; CTRP2 5.0058 6.883 4.0927 4.0753
OVCAR-8 GDSC1; GDSC2; CTRP2; CTRP1 5.137 10.0237 2.6413 9.9859
A2780 GDSC1; GDSC2; CTRP2; CTRP1 5.1497 7.6696 3.8284 4.9946
OVCAR-5 GDSC1; GDSC2; CTRP2 5.1992 11.6017 1.8939 12.8407
ES-2 GDSC1; GDSC2 5.2607 6.8853 2.783 0.4334
OV7 CTRP2; CTRP1 5.2651 8.9946 3.2602 7.1635
COV644 CTRP2; CTRP1 5.3032 7.6202 3.9757 4.0986
OVK18 GDSC2; CTRP2; CTRP1 5.3202 7.971 3.8145 4.7431
OV56 GDSC2; CTRP2 5.3266 6.7548 4.4114 2.1631
COV362 CTRP2; CTRP1 5.3526 8.512 3.5706 5.7056
OVSAHO CTRP2 5.3552 7.0625 4.2812 2.6558
Caov-4 GDSC1; GDSC2 5.359 12.6298 0.2369 13.4726
ES2 CTRP2 5.3623 6.4128 4.6036 1.3219
Kuramochi GDSC1; GDSC2; CTRP2 5.3778 8.3695 3.6509 5.2446
ONCO-DG-1 CTRP2 5.4174 7.3735 4.1742 2.9977
OVCAR-4 GDSC1; GDSC2; CTRP2; CTRP1 5.42 8.4958 3.6313 5.3336
OAW42 GDSC1; GDSC2; CTRP2; CTRP1 5.4246 7.4198 4.1676 3.0938
EFO-27 GDSC1; GDSC2; CTRP2; CTRP1 5.5631 7.3743 4.2897 2.3774
Caov-3 GDSC1; GDSC2; CTRP2; CTRP1 5.6452 7.8267 4.1279 2.9133
OVKATE GDSC1; GDSC2; CTRP1 5.7737 7.6575 4.2961 2.6431
SK-OV-3 GDSC1; GDSC2; CTRP2 5.8008 8.106 4.0889 2.7698
MCAS CTRP2 5.8376 7.4121 4.4381 1.3635
JHOC-5 CTRP2; CTRP1 5.8601 7.9651 4.207 2.2953
SNU-840 CTRP2; CTRP1 5.8658 8.2813 4.0604 2.8686
HEY A8 CTRP2 5.9098 8.2217 4.1062 2.5528
JHOM-1 CTRP2; CTRP1 5.9206 7.8362 4.3058 1.836
RMUG-S CTRP1 5.9895 16.1571 0.265 28.5567
EFO-21 GDSC1; GDSC2; CTRP2 6.212 8.1337 4.3301 1.3611
TYK-nu GDSC1; GDSC2; CTRP2; CTRP1 6.2609 9.1066 3.9276 2.8715
RMG-I GDSC1; GDSC2; CTRP2; CTRP1 6.2784 10.2661 3.3882 4.9821
OVISE GDSC1; GDSC2; CTRP2 6.392 13.5279 1.8667 10.8305
TOV-21G GDSC1; GDSC2; CTRP2 6.7409 8.3195 4.5133 0.4312
OAW28 GDSC1; GDSC2; CTRP2 6.7866 12.6859 2.5601 7.4853
OVTOKO GDSC1; GDSC2; CTRP2 6.8002 16.8171 0.5495 15.0051
TOV-112D GDSC1; GDSC2; CTRP2 7.1628 11.0291 3.5788 3.0751
OVMANA CTRP1 7.577 12.6295 3.1094 8.9593
FU-OV-1 GDSC1; GDSC2; CTRP2 8.1498 19.828 0.0534 14.5368
OV-90 GDSC1; GDSC2; CTRP2; CTRP1 8.7975 16.9975 1.8429 7.6071
IGROV-1 GDSC1; GDSC2; CTRP2; CTRP1 9.12 18.5969 1.3009 9.1119
OVCAR-3 GDSC1; GDSC2 9.2059 21.4103 -1.4161 11.9873
COV318 CTRP1 9.2068 15.7772 2.6342 8.5103
SNU-8 CTRP2 10.2645 22.4533 0.2104 11.2253
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; GDSC2; CTRP2 3.5621 6.8443 2.7335 13.0121
MPP 89 GDSC1; GDSC2; CTRP2 4.5535 9.244 2.5227 11.5709
NCI-H2452 GDSC1; GDSC2; CTRP2 5.0915 7.2682 3.9715 4.4194
NCI-H28 GDSC1; GDSC2; CTRP2 5.1799 12.1342 1.6118 13.9936
NCI-H2052 GDSC1; GDSC2; CTRP2 5.199 9.3433 3.0224 8.2015
IST-Mes1 GDSC1; GDSC2; CTRP2 5.5306 13.8795 1.0253 15.5534
ACC-MESO-1 CTRP2 5.9232 8.2777 4.0884 2.6049
JL-1 CTRP2 6.9154 13.8095 2.1063 9.0762
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP GDSC1; GDSC2; CTRP2 0.7808 7.2401 -0.3498 32.031
LNCaP clone FGC GDSC1; GDSC2; CTRP2 4.8666 7.3024 3.764 5.7354
22Rv1 GDSC1; GDSC2; CTRP2 5.0107 11.2989 1.889 13.2269
PC-3 GDSC1; GDSC2 5.0717 7.4707 2.4604 1.6741
NCI-H660 GDSC2 5.1133 6.6757 2.801 0.5526
DU145 GDSC1; GDSC2; CTRP2 5.1259 6.9804 4.1435 3.6325
PaCa-3 CTRP2; CTRP1 5.6003 7.5743 4.2188 2.6103
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 4.1125 5.1961 3.5539 2.3446
A-253 GDSC1; GDSC2; CTRP2 5.2102 6.8378 4.2818 2.8993
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 6.4256 21.2136 -3.1876 21.8054
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCC-StC-K140 CTRP2 -0.6006 3.3948 -4.4387 6.1555
GSS CTRP2 1.4425 4.8772 1.1579 24.9807
ECC10 GDSC1; GDSC2; CTRP2 2.0797 7.745 0.8146 24.3174
RERF-GC-1B GDSC1; GDSC2 2.1322 7.2546 0.2934 18.914
SNU-16 GDSC1; GDSC2; CTRP2 2.9494 4.5574 2.8702 14.2282
HSC-39 GDSC1; GDSC2 3.3629 5.6597 2.187 7.0659
HuG1-N CTRP2 3.5157 10.6291 0.8942 20.3055
SNU-719 CTRP2 3.5752 8.6004 1.3911 13.1614
OCUM-1 GDSC1; GDSC2; CTRP2 4.0402 7.6229 2.8457 11.38
SCH GDSC1; GDSC2 4.1394 6.6144 2.2971 4.4605
SNU-1 GDSC1; GDSC2; CTRP2 4.305 7.6045 3.1058 9.6969
MKN28 GDSC1; GDSC2 4.4329 9.084 1.3061 8.1862
HGC-27 GDSC1; GDSC2; CTRP2 4.4896 6.452 3.8378 6.2549
Fu97 GDSC1; GDSC2; CTRP2 4.6057 7.489 3.4397 7.6426
KATO III GDSC2; CTRP2 4.7669 6.5134 4.0675 4.675
Hs 746.T GDSC2; CTRP2 4.789 6.513 4.0877 4.543
NUGC-4 GDSC1; GDSC2; CTRP2 4.9224 5.8625 4.5297 2.4113
SH-10-TC CTRP2 5.0466 6.328 4.4045 2.6855
SNU-620 CTRP2 5.073 6.1311 4.5247 2.1298
LMSU CTRP2 5.1959 6.9477 4.2159 3.2007
TMK-1 GDSC1; GDSC2 5.2858 12.29 0.3503 13.0637
GSU CTRP2 5.3149 6.946 4.3086 2.6084
RF-48 GDSC1; GDSC2 5.3647 7.2749 2.6788 0.662
SNU-216 CTRP2 5.3752 6.7031 4.472 1.8376
KE-39 CTRP2 5.4011 8.5679 3.5703 5.5407
SNU-5 GDSC1; GDSC2; CTRP2 5.43 8.2809 3.7351 4.8024
SNU-668 CTRP2 5.4707 10.2501 2.0689 6.5641
NCI-N87 GDSC1; GDSC2; CTRP2 5.4987 10.7528 2.5594 9.576
MKN1 GDSC1; GDSC2; CTRP2 5.5653 8.0202 3.9651 3.6246
TGBC11TKB GDSC1; GDSC2 5.5807 11.7181 0.8241 8.4578
SNU-601 CTRP2 5.5877 8.7644 3.6154 5.0356
23132/87 GDSC1; GDSC2; CTRP2 5.6036 8.4362 3.789 4.2906
MKN7 GDSC1; GDSC2; CTRP2 5.6149 7.586 4.2119 2.5395
GCIY GDSC1; GDSC2 5.7555 13.9795 -0.1404 12.4776
ECC12 GDSC2; CTRP2 5.9175 7.3609 4.5074 1.0277
SK-GT-2 GDSC2 5.9806 8.4712 2.4832 0.8667
MKN74 CTRP2; CTRP1 6.1673 12.2758 2.3274 9.4462
IM95 GDSC1; GDSC2; CTRP2 6.2812 13.3468 1.8735 10.9868
MKN45 GDSC1; GDSC2; CTRP2 6.3245 7.0719 4.8047 0.052
AGS GDSC1; GDSC2; CTRP2; CTRP1 7.7907 9.4962 4.5094 0.1508
NUGC-3 GDSC1; GDSC2; CTRP2 7.9119 9.9713 4.373 0.2863
SNU-1077 CTRP2 4.2516 7.0484 3.3237 8.9237
SNU-685 CTRP2 5.4331 7.8765 3.9378 3.9529
SNG-M GDSC1; GDSC2; CTRP2; CTRP1 6.9635 9.9388 3.9638 1.9749
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMH-2 GDSC1; GDSC2 1.4599 7.0514 -0.2554 27.6777
TT GDSC1; GDSC2; CTRP2 3.781 6.3211 3.1878 10.6439
HTC-C3 GDSC1; GDSC2 4.1883 7.6725 1.8195 6.0506
IHH-4 GDSC1; GDSC2 4.2738 6.7075 2.3415 3.2685
FTC-238 CTRP2 4.4212 6.1116 3.9316 6.0382
SW579 CTRP2 4.5645 6.0275 4.1121 4.9554
ASH-3 GDSC1; GDSC2 4.5689 8.5814 1.6449 6.2299
ML-1 [Human leukemia] GDSC1; GDSC2; CTRP2 5.0921 6.6672 4.2724 3.154
TT2609-C02 GDSC1; GDSC2; CTRP2 5.1233 7.9145 3.6745 5.6074
BHT-101 GDSC1; GDSC2; CTRP2 5.2235 12.4503 1.4896 14.3847
CAL-62 GDSC1; GDSC2; CTRP2 5.4516 9.0622 3.3639 6.3148
FTC-133 GDSC1; GDSC2; CTRP2 5.4901 7.3289 4.2489 2.5751
B-CPAP GDSC1; GDSC2; CTRP2 5.6134 8.3306 3.848 4.0314
CGTH-W-1 GDSC1; GDSC2; CTRP2 5.6452 7.2222 4.4063 1.7201
K5 GDSC1; GDSC2 6.206 13.1867 0.536 8.7521
WRO GDSC1; GDSC2 7.4706 17.5975 -0.7255 11.9895
8505C GDSC1; GDSC2; CTRP2 7.5164 13.3287 2.7365 5.815
8305C GDSC1; GDSC2; CTRP2 9.049 20.5575 0.3178 12.4244
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DOK GDSC1; GDSC2 0.6859 9.6153 -2.2224 33.0552
YD-10B CTRP2 1.4584 5.8507 0.8844 25.8955
BB49-HNC GDSC1; GDSC2 1.8529 10.0142 -1.3155 26.4723
LB771-HNC GDSC1; GDSC2 2.3017 9.1158 -0.4638 21.8294
SAT [Human HNSCC] GDSC1; GDSC2 3.3188 6.5383 1.7111 8.4979
JHU-011 GDSC1; GDSC2 3.5754 11.8806 -0.7481 22.5813
PCI-38 GDSC1 3.79 5.8007 0.6904 0.7736
SNU-1214 CTRP2 3.8733 7.909 2.5484 12.988
BICR 78 GDSC1; GDSC2 4.0581 6.8007 2.1513 4.6013
YD-8 CTRP2 4.2368 8.6982 2.5074 12.3201
KON GDSC1; GDSC2 4.2542 13.6151 -1.0699 22.0205
NCI-H3118 GDSC1; GDSC2 4.3753 8.5673 1.5168 7.2332
PCI-04B GDSC1; GDSC2 4.4823 6.6905 2.4782 2.3012
OSC-20 GDSC1; GDSC2 4.5818 6.6813 2.5397 1.8933
HO-1-u-1 GDSC1; GDSC2 4.5937 8.0682 1.9066 5.8545
BICR 22 GDSC1; GDSC2; CTRP2 4.6953 8.44 3.0476 9.0903
SCC-25 GDSC1; GDSC2; CTRP2 4.8071 8.7288 3.0009 9.0555
SNU-899 CTRP2 4.9175 6.4028 3.5265 1.2358
OSC-19 GDSC1; GDSC2 4.9231 9.3487 1.5158 7.4671
UPCI-SCC-090 GDSC1; GDSC2 4.9439 8.8319 1.7728 4.968
PE/CA-PJ34 (clone C12) CTRP2 4.944 6.7005 4.1313 4.0365
CAL-33 GDSC1; GDSC2; CTRP2 4.9693 7.4913 3.7579 5.5544
HO-1-N-1 GDSC1; GDSC2 5.1534 10.0848 1.318 6.8281
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 5.1668 6.6881 4.3222 2.8074
HSC-3 GDSC1; GDSC2; CTRP2 5.1739 8.5816 2.6687 4.447
JHU-022 GDSC1; GDSC2 5.192 12.1353 0.3597 11.3019
FaDu GDSC1; GDSC2; CTRP2 5.1996 6.8711 4.2569 3.0224
SAS GDSC1; GDSC2 5.205 13.5263 -0.3087 14.2319
HSC-2 GDSC1; GDSC2; CTRP2 5.221 7.4351 3.9928 4.0908
SNU-1066 CTRP2 5.2621 7.7279 3.8794 4.4924
CAL-27 GDSC1; GDSC2; CTRP2 5.3064 6.8032 4.3726 2.3566
BICR 16 CTRP2 5.3711 7.363 4.1448 3.1958
BICR 6 CTRP2 5.4055 7.8499 3.93 4.0316
Detroit 562 GDSC1; GDSC2; CTRP2 5.4682 8.435 3.688 4.9338
BICR 31 GDSC1; GDSC2; CTRP2 5.5076 8.8444 3.5153 5.5866
BHY GDSC1; GDSC2; CTRP2 5.5305 11.1627 2.3803 10.2539
PCI-15A GDSC1; GDSC2 5.6606 7.9995 2.5265 1.1255
HSC-4 GDSC1; GDSC2; CTRP2 5.7085 7.5024 4.3151 1.9957
PE/CA-PJ49 CTRP2 5.7943 11.7357 2.3013 10.1088
SKN-3 GDSC1; GDSC2 5.8735 13.2406 0.294 10.3758
PCI-06A GDSC1; GDSC2 6.0687 7.8966 2.7301 0.3018
SNU-1041 CTRP2 6.138 11.2454 2.8013 7.5007
BB30-HNC GDSC1; GDSC2 6.1744 13.7102 0.2692 11.6271
SCC-15 GDSC1; GDSC2 6.1964 13.1507 0.5467 8.7196
SNU-1076 CTRP2 6.2046 9.424 3.7296 3.6471
SCC-9 GDSC1; GDSC2; CTRP2; CTRP1 6.3003 13.9566 1.5975 12.0936
JHU-029 GDSC1; GDSC2 6.7148 18.1453 -1.4881 18.0303
KOSC-2 GDSC1; GDSC2 6.7161 18.2759 -1.5503 18.2538
BICR 56 CTRP2 6.8146 8.5966 4.4378 0.5772
SNU-46 CTRP2 7.0921 24.4257 -3.6991 23.1181
Ca9-22 GDSC1; GDSC2 7.1235 18.0592 -1.1701 14.1938
PE/CA-PJ41 (clone D2) CTRP2 7.132 8.8566 4.4733 0.3537
SCC-4 GDSC1; GDSC2; CTRP2 7.25 18.0814 0.2602 15.2475
PCI-30 GDSC1; GDSC2 7.3742 21.9856 -2.8866 21.3214
BICR 10 GDSC1; GDSC2 7.4747 18.4777 -1.1375 13.5138
BICR 18 CTRP2 7.7163 9.4437 4.4864 0.1722
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-1 CTRP2 2.8168 7.0059 1.895 18.2629
RT-112 GDSC1; GDSC2; CTRP2 4.1959 7.9835 2.8192 11.1277
JMSU-1 CTRP2 4.3741 6.4812 3.7122 7.0434
5637 GDSC1; GDSC2; CTRP2 4.4521 8.7122 2.6962 11.069
HT-1197 GDSC1; GDSC2; CTRP2 4.5507 7.2602 3.5022 7.5027
BC-3C CTRP2 4.6797 6.6253 3.9327 5.4281
SW780 GDSC1; GDSC2 4.9999 6.5987 2.7821 0.5779
647V GDSC1; GDSC2; CTRP2 5.2222 7.5 3.9614 4.2203
T24 GDSC1; GDSC2; CTRP2 5.3898 7.8692 3.9085 4.148
TCCSUP GDSC1; GDSC2; CTRP2 5.391 8.6678 3.5128 5.799
253J CTRP2 5.4259 8.7731 3.4877 5.8427
KMBC-2 CTRP2 5.4865 8.1305 3.8525 4.2186
BFTC-905 GDSC1; GDSC2 5.4955 13.3971 -0.0393 12.5183
VM-CUB-1 CTRP2 5.4966 7.4876 4.1761 2.8642
SCaBER CTRP2 5.5228 7.933 3.9768 3.644
253J-BV CTRP2 5.5324 8.1795 3.8626 4.1013
KU-19-19 GDSC1; GDSC2; CTRP2 5.5701 8.7162 3.6261 5.0206
639V GDSC1; GDSC2; CTRP2 5.9291 7.5172 4.4443 1.2412
SW1710 GDSC1; GDSC2; CTRP2 6.1227 8.8771 3.9349 2.9465
HT-1376 GDSC1; GDSC2; CTRP2 6.2001 12.245 2.356 9.2048
UM-UC-3 GDSC1; GDSC2; CTRP2 6.4098 9.6587 3.7517 3.2942
RT-4 GDSC1; GDSC2; CTRP2 6.4364 8.8015 4.1599 1.7389
CAL-29 GDSC1; GDSC2; CTRP2 6.8156 8.3543 4.5316 0.3579
J82 GDSC1; GDSC2; CTRP2 6.8358 12.2073 2.8235 6.3745
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DSH1 GDSC1; GDSC2 3.2855 7.7692 1.0679 11.9252
PA-1 GDSC1; GDSC2 3.3063 6.8004 1.5697 9.2705
NEC8 GDSC1; GDSC2 3.6333 8.8563 0.8098 12.3987
TC-YIK GDSC2 3.7298 8.2569 1.1855 10.2736
JEG-3 GDSC1; GDSC2 3.7351 5.5515 2.5299 3.9333
JAR GDSC1; GDSC2 3.871 5.5692 2.6164 3.1001
LB831-BLC GDSC1; GDSC2 4.1062 6.6007 2.2811 3.8544
JHOS-3 GDSC2 4.1747 6.152 2.5387 2.9585
SW756 GDSC1; GDSC2 4.1983 8.4651 1.4391 7.9756
C-4-I GDSC1; GDSC2 4.2525 5.9969 2.6573 1.7901
UWB1.289 GDSC2 4.3531 7.5505 1.993 5.8389
PWR-1E GDSC2 4.3609 9.3424 1.1275 9.2245
CAL-39 GDSC1; GDSC2 4.3675 11.3828 0.1263 14.0334
HT-3 GDSC1; GDSC2 4.5262 7.906 1.9391 4.8367
MS751 GDSC1; GDSC2 4.5761 11.5013 0.2246 13.1413
SiSo GDSC1; GDSC2 4.612 7.6949 2.0943 3.9344
SiHa GDSC1; GDSC2 4.7617 8.3938 1.862 4.8262
NCC-IT GDSC1; GDSC2 4.7995 11.9318 0.1778 15.0549
ACC-OV7 GDSC2 4.8365 9.7807 1.251 9.1707
OVCA420 GDSC2 4.8401 7.0806 2.5061 2.0818
HEC-1 GDSC1; GDSC2 4.9031 6.6172 2.7314 0.807
HEY GDSC2 5.0875 8.3279 2.0923 3.2519
C-33 A GDSC1; GDSC2 5.1093 10.8612 0.9178 8.8328
HeLa GDSC1; GDSC2; CTRP2 5.2665 12.1612 1.6693 13.6016
OVMIU GDSC1; GDSC2 5.5592 15.2858 -0.9134 15.998
DoTc2 4510 GDSC1; GDSC2 5.6162 13.5446 -0.0267 12.2409
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 5.6886 7.3853 2.7689 0.3534
SKN GDSC1; GDSC2 5.7667 8.6318 2.3218 1.5548
BPH-1 GDSC1; GDSC2 5.7919 16.6776 -1.4261 17.4642
SW954 GDSC1; GDSC2 5.9044 7.5506 2.7908 0.2357
SW962 GDSC1; GDSC2 5.9414 17.3091 -1.627 20.1186
OV17R GDSC2 6.1254 8.5092 2.5297 0.7921
NT2-D1 GDSC1; GDSC2 6.4195 19.1477 -2.1816 21.0065
OVCA433 GDSC2 6.4301 8.8248 2.5355 0.6138
Ca Ski GDSC1; GDSC2 6.4338 13.6986 0.4409 8.8155
ME-180 GDSC1; GDSC2 6.9713 16.2006 -0.3893 11.4537
PEO1 GDSC2 7.1122 16.3291 -0.3594 11.114
KGN GDSC1; GDSC2 7.4378 19.9349 -1.8554 17.9582
SKG-IIIa GDSC1; GDSC2 7.739 16.6448 -0.1175 9.2308
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7423).
2 Imidazo[2,1-b]thiazoles: multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family... Bioorg Med Chem Lett. 2010 Apr 15;20(8):2452-5.
3 Screening of Organophosphate Flame Retardants with Placentation-Disrupting Effects in Human Trophoblast Organoid Model and Characterization of Adverse Pregnancy Outcomes in Mice. Environ Health Perspect. 2022 May;130(5):57002. doi: 10.1289/EHP10273. Epub 2022 May 3.