Details of the Drug

General Information of Drug (ID: DMKA2YS)

Drug Name
MG-132
Synonyms
MG-132; Z-Leu-leu-leu-al; MG132; Zlllal; MG 132; Z-LLL-CHO; Zlll-cho; Z-Leu-leu-leucinal; Z-Leu-Leu-Leu-H; Z-Leu-Leu-Leu-CHO; Carbobenzoxy-leucyl-leucyl-leucinal; UNII-RF1P63GW3K; Benzyloxycarbonyl-leu-leu-leu-aldehyde; Benzyloxycarbonyl-leucyl-leucyl-leucinal; Lll cpd; Carbobenzoxyl-leucinyl-leucinyl-leucinal-H; Cbz-Leu-Leu-Leu-H; Benzyloxycarbonylleucyl-leucyl-leucine aldehyde; benzyl (S)-4-methyl-1-((S)-4-methyl-1-((S)-4-methyl-1-oxopentan-2-ylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-ylcarbamate; RF1P63GW3K
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski):
1		 Molecular Weight 475.6
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 15
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 5
Chemical Identifiers
Formula
C26H41N3O5
IUPAC Name
benzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate
Canonical SMILES
CC(C)CC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1
InChI
InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22-,23-/m0/s1
InChIKey
TZYWCYJVHRLUCT-VABKMULXSA-N
Cross-matching ID
PubChem CID
462382
ChEBI ID
CHEBI:75142
CAS Number
133407-82-6
VARIDT ID
DR01613
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
26S proteasome non-ATPase regulatory subunit 1 (PSMD1) OTW258OV PSMD1_HUMAN Gene/Protein Processing [2]
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) OT8KO67V PSD11_HUMAN Gene/Protein Processing [2]
26S proteasome non-ATPase regulatory subunit 12 (PSMD12) OTWICA51 PSD12_HUMAN Gene/Protein Processing [2]
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) OTNQ351N PSD13_HUMAN Gene/Protein Processing [2]
26S proteasome non-ATPase regulatory subunit 14 (PSMD14) OTJWHMZ5 PSDE_HUMAN Gene/Protein Processing [2]
26S proteasome non-ATPase regulatory subunit 2 (PSMD2) OT6HZHN7 PSMD2_HUMAN Gene/Protein Processing [2]
26S proteasome non-ATPase regulatory subunit 3 (PSMD3) OT585WY8 PSMD3_HUMAN Gene/Protein Processing [2]
26S proteasome non-ATPase regulatory subunit 6 (PSMD6) OTX59EGK PSMD6_HUMAN Gene/Protein Processing [2]
26S proteasome non-ATPase regulatory subunit 8 (PSMD8) OTY6X27P PSMD8_HUMAN Gene/Protein Processing [2]
26S proteasome regulatory subunit 10B (PSMC6) OTG8997V PRS10_HUMAN Gene/Protein Processing [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 42 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 -2.8805 -1.2265 -2.8828 60.8727
ES6 GDSC1; GDSC2 -5.0975 -1.3854 -5.1474 68.4381
CAL-78 GDSC2 -2.3271 -0.1032 -2.3548 53.9317
CHSA8926 GDSC2 -2.2661 0.3653 -2.3322 53.0964
SK-PN-DW GDSC1; GDSC2 -2.1422 -0.6193 -2.1457 41.4376
ES8 GDSC1; GDSC2 -2.0646 -0.0233 -2.0877 40.7461
CAL-72 GDSC2 -1.9946 0.0405 -2.019 49.9338
ES1 GDSC1; GDSC2 -1.8019 2.1103 -2.1798 39.4689
EW-7 GDSC2 -1.7935 0.213 -1.8218 47.4834
EW-11 GDSC1; GDSC2 -1.6287 4.008 -2.6449 39.8121
HuO9 GDSC2 -1.6208 0.6335 -1.6793 45.4522
EW-3 GDSC1; GDSC2 -1.3084 1.8188 -1.5627 34.2836
H-EMC-SS GDSC1; GDSC2 -1.254 0.47 -1.2784 32.6615
EW-18 GDSC1; GDSC2 -1.0472 2.6794 -1.533 32.7955
CHSA0108 GDSC2 -0.9296 1.282 -1.0336 29.925
ES5 GDSC1; GDSC2 -0.8948 0.8759 -0.938 29.1653
CADO-ES1 GDSC2 -0.8764 0.6773 -0.9002 36.0986
NY GDSC2 -0.6889 1.3353 -0.7834 34.1807
ES4 GDSC1; GDSC2 -0.6883 1.9938 -0.9322 28.1328
EW-24 GDSC1; GDSC2 -0.638 1.3104 -0.7242 26.8193
ES7 GDSC1; GDSC2 -0.6113 1.3693 -0.7056 26.5944
SJSA-1 GDSC1; GDSC2 -0.6085 1.4826 -0.724 26.6764
EW-1 GDSC1; GDSC2 -0.5847 2.075 -0.8416 27.1735
EW-22 GDSC1; GDSC2 -0.5532 1.7928 -0.7327 26.4573
TC-71 GDSC1; GDSC2 -0.4571 0.855 -0.4763 24.6679
SK-ES-1 GDSC1; GDSC2 -0.4187 1.6074 -0.5437 24.8306
MHH-ES-1 GDSC2 -0.4186 1.5873 -0.5393 24.8938
NOS-1 [Human HNSCC] GDSC1; GDSC2 -0.3526 1.6117 -0.4728 24.1456
A-673 GDSC2; CTRP2 -0.3398 1.0093 -0.3405 31.0789
G-292 clone A141B1 GDSC2 -0.3128 2.299 -0.6115 30.7703
U2OS GDSC2 -0.2851 1.5826 -0.3935 23.4917
SaOS-2 GDSC2 -0.236 1.821 -0.3938 28.9529
EW-16 GDSC1; GDSC2 -0.1641 1.7292 -0.2937 22.3125
HuO-3N1 GDSC2 -0.1487 2.095 -0.3715 28.2855
SK-N-MC CTRP2 -0.1142 0.4366 -0.1142 29.5724
EW-12 GDSC1; GDSC2 -0.0973 0.7844 -0.1016 20.995
U-CH2 GDSC2 0.0675 2.5642 -0.2862 21.2955
CHSA0011 GDSC2 0.1471 2.8802 -0.3159 21.1134
EW-13 GDSC1; GDSC2 0.4635 2.0427 0.3114 16.1656
TC71 CTRP2 0.5421 1.5926 0.5418 25.1986
MG-63 GDSC2; CTRP2 0.6675 1.7065 0.6671 24.363
HOS GDSC2; CTRP2 1.4101 2.1514 1.41 19.4117
⏷ Show the Full List of 42 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 185 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 -0.2161 0.344 -0.2161 30.2516
JM1 GDSC1; GDSC2; CTRP2 -1.842 -1.0024 -1.842 41.0908
NCI-H929 GDSC2 -4.0355 -2.3217 -4.0362 74.6924
RS4;11 GDSC1; GDSC2 -3.8731 0.3691 -4.0492 57.4789
SU-DHL-6 GDSC1; GDSC2 -3.6796 -2.2948 -3.6798 56.7902
ML-2 GDSC1; GDSC2 -3.2796 -1.3753 -3.2835 52.7785
DEL GDSC1; GDSC2 -3.2296 0.086 -3.3211 52.1342
P12-Ichikawa GDSC2 -3.128 -0.868 -3.142 63.4233
Farage GDSC1; GDSC2 -3.0547 -1.6372 -3.0552 50.5467
KE-37 GDSC1; GDSC2 -2.9736 -1.8157 -2.9737 49.7358
AMO1 GDSC1; GDSC2 -2.8051 -1.4497 -2.8057 48.0526
Loucy GDSC1; GDSC2 -2.736 -0.9798 -2.7402 47.3701
MM1.S GDSC2 -2.7046 -1.1525 -2.7064 58.7359
JJN-3 GDSC1; GDSC2 -2.6307 -1.2066 -2.6318 46.3109
Karpas-620 GDSC2 -2.6293 -1.6061 -2.6293 57.8619
SU-DHL-5 GDSC2 -2.617 -1.2472 -2.6177 57.6828
PF-382 GDSC1; GDSC2 -2.5673 -1.3217 -2.5676 45.6743
Karpas-1106P GDSC2 -2.5605 -1.3168 -2.5609 56.9923
LAMA-84 GDSC1; GDSC2 -2.5225 -1.0152 -2.5244 45.2318
DND-41 GDSC1; GDSC2 -2.5185 -1.1186 -2.5196 45.1893
SU-DHL-16 GDSC1; GDSC2 -2.5157 -1.8649 -2.5157 45.1571
HEL GDSC1; GDSC2 -2.51 -1.4765 -2.51 45.1
CML-T1 GDSC2 -2.5006 -1.1725 -2.5013 56.239
TALL-1 [Human adult T-ALL] GDSC2 -2.4959 -0.7322 -2.5018 45.1372
KMS-11 GDSC2 -2.4805 -1.3484 -2.4807 44.9632
KCL-22 GDSC1; GDSC2 -2.4629 -1.1317 -2.4636 44.6319
CRO-AP2 GDSC2 -2.4559 -1.3306 -2.456 44.7157
EM-2 GDSC1; GDSC2 -2.4416 2.4576 -2.9795 45.4964
L-1236 GDSC1; GDSC2 -2.441 -0.8252 -2.4445 44.4239
U266B1 GDSC1; GDSC2 -2.4371 -1.1324 -2.4378 44.3743
WIL2 NS GDSC1; GDSC2 -2.4209 -1.5097 -2.4209 44.2088
SU-DHL-4 GDSC1; GDSC2 -2.4178 -1.8967 -2.4178 44.1777
MOLT-16 GDSC1; GDSC2 -2.3855 -1.4719 -2.3855 43.8551
L-540 GDSC1; GDSC2 -2.3443 -0.837 -2.3468 43.4536
OCI-AML-2 GDSC1; GDSC2 -2.329 -1.6806 -2.329 43.2902
H9 GDSC1; GDSC2 -2.3258 -1.4652 -2.3258 43.2577
L-363 GDSC1; GDSC2 -2.321 -1.7759 -2.321 43.2097
NB4 GDSC1; GDSC2 -2.3046 -1.5359 -2.3046 43.0458
MOLT-4 GDSC1; GDSC2 -2.3032 -1.5461 -2.3032 43.0319
SR GDSC1; GDSC2 -2.2924 -1.0365 -2.293 42.9269
MY-M12 GDSC1; GDSC2 -2.2906 -1.2459 -2.2908 42.907
BALL-1 GDSC1; GDSC2 -2.2783 -1.0442 -2.2789 42.7859
U-698-M GDSC1; GDSC2 -2.2667 1.5062 -2.5314 43.4431
NK-92MI GDSC1; GDSC2 -2.2567 -1.3857 -2.2567 42.5672
KM-H2 GDSC1; GDSC2 -2.2408 -1.4065 -2.2408 42.4079
SU-DHL-1 GDSC1; GDSC2 -2.211 -1.335 -2.211 42.1096
SU-DHL-10 GDSC2 -2.2074 -1.0717 -2.2077 52.5902
CTV-1 GDSC1; GDSC2 -2.2017 -1.2915 -2.2018 42.0175
VL51 GDSC1; GDSC2 -2.1996 -1.3161 -2.1997 41.9964
DoHH2 GDSC1; GDSC2 -2.1977 -0.4331 -2.2063 42.0141
HT GDSC1; GDSC2 -2.1675 -1.6068 -2.1675 41.6752
KMS-12-BM GDSC1; GDSC2 -2.1436 -0.9248 -2.1443 41.4395
P32/ISH GDSC1; GDSC2 -2.123 -1.3103 -2.123 41.23
CESS GDSC1; GDSC2 -2.1151 -0.8567 -2.116 41.1551
DG-75 GDSC1; GDSC2 -2.1097 0.1019 -2.143 41.2359
BC-3 GDSC1; GDSC2 -2.1088 -1.1888 -2.1089 41.0885
ARH-77 GDSC1; GDSC2 -2.1043 -1.1775 -2.1044 41.0436
JSC-1 GDSC2 -2.0698 -0.07 -2.0904 50.8514
NALM-6 GDSC1; GDSC2 -2.0494 -1.2392 -2.0494 40.494
HC-1 GDSC1; GDSC2 -2.0207 -1.0309 -2.0208 40.2079
KOPN-8 GDSC2 -2.0026 0.2116 -2.0399 50.0316
MOLM-13 GDSC1; GDSC2 -1.9625 0.5378 -2.0304 39.9135
GR-ST GDSC1; GDSC2 -1.9175 3.2912 -2.6864 41.5742
MHH-CALL-2 GDSC2 -1.9155 -0.2789 -1.9232 48.953
MOLT-13 GDSC2 -1.8718 -0.0603 -1.8867 48.4227
Karpas-45 GDSC1; GDSC2 -1.8158 -0.6441 -1.8166 38.162
EoL-1 GDSC1; GDSC2; CTRP2 -1.8156 0.3243 -1.8192 40.926
SU-DHL-8 GDSC1; GDSC2 -1.7785 -0.4191 -1.7813 37.799
ATN-1 GDSC1; GDSC2 -1.7548 2.8441 -2.3558 39.7346
TK [Human B-cell lymphoma] GDSC1; GDSC2 -1.732 -0.4701 -1.7337 37.3284
SUP-HD1 GDSC1; GDSC2; CTRP2 -1.7233 1.0422 -1.7437 40.3607
VAL GDSC1; GDSC2 -1.7107 0.3252 -1.7439 37.2637
MOLM-16 GDSC2 -1.6668 0.3214 -1.6977 36.9446
MHH-CALL-4 GDSC2 -1.6346 0.2756 -1.6607 36.5996
LP-1 GDSC1; GDSC2; CTRP2 -1.6331 -0.5045 -1.6331 39.6982
HDLM-2 GDSC1; GDSC2 -1.627 -0.0928 -1.6347 36.3074
KG-1 GDSC1; GDSC2 -1.6026 -0.092 -1.6098 36.0617
JURL-MK1 GDSC1; GDSC2 -1.5818 0.9073 -1.6739 36.2485
Ku812 GDSC1; GDSC2 -1.5504 0.2874 -1.5741 35.6197
ALL-PO GDSC1; GDSC2 -1.4646 0.3161 -1.4868 34.7553
Hs 445 GDSC1; GDSC2 -1.4534 -0.0258 -1.4597 34.5652
LC4-1 GDSC1; GDSC2 -1.4225 0.353 -1.4455 34.3384
BONNA-12 GDSC2 -1.4172 0.1127 -1.4274 34.3425
Karpas-231 GDSC1; GDSC2 -1.404 -0.0752 -1.4084 34.0618
697 GDSC1; GDSC2; CTRP2 -1.3189 0.3698 -1.3199 37.6068
MEG-01 GDSC1; GDSC2 -1.2975 0.5024 -1.3262 33.1176
GDM-1 GDSC1; GDSC2 -1.2853 0.6789 -1.3295 33.0723
SK-MM-2 GDSC1; GDSC2 -1.2777 1.1666 -1.3888 33.3199
KY821 GDSC1; GDSC2 -1.2537 0.5995 -1.2886 32.7102
KMOE-2 GDSC1; GDSC2 -1.2156 0.5779 -1.2468 32.3114
Sc-1 GDSC1 -1.2059 -0.6207 -1.2116 15.109
DB GDSC1; GDSC2; CTRP2 -1.2038 -0.0309 -1.2038 36.8361
Jurkat GDSC2 -1.1647 0.5261 -1.1895 39.6972
NU-DUL-1 GDSC1; GDSC2 -1.1604 0.1733 -1.1671 31.6375
Daudi GDSC1; GDSC2; CTRP2 -1.1376 0.0704 -1.1376 36.3948
WSU-DLCL2 GDSC1; GDSC2 -1.0648 0.7889 -1.1083 30.8659
CTB-1 GDSC1; GDSC2 -1.0612 0.7631 -1.1018 30.8154
CCRF-CEM GDSC1; GDSC2 -1.047 2.3959 -1.4412 32.3803
SCC-3 GDSC1; GDSC2 -1.0209 0.8093 -1.0641 30.4259
JVM-2 GDSC1; GDSC2 -0.9509 1.5674 -1.1134 30.326
JeKo-1 GDSC2; CTRP2 -0.9443 0.1771 -0.9443 35.1064
ALL-SIL GDSC1; GDSC2 -0.9392 0.8296 -0.9799 29.5966
Ramos.2G6.4C10 GDSC1; GDSC2 -0.9258 0.5216 -0.9412 29.3353
L-428 GDSC1; GDSC2 -0.9145 0.6238 -0.936 29.2529
MV4-11 GDSC1; GDSC2 -0.9043 0.522 -0.919 29.1166
RPMI-8402 GDSC1; GDSC2 -0.9043 0.2892 -0.9095 29.0689
RPMI-8866 GDSC1; GDSC2 -0.8741 0.9413 -0.9235 28.9901
Mono-Mac-6 GDSC1; GDSC2 -0.869 1.7496 -1.0663 29.6874
SUP-B8 GDSC2 -0.843 0.6238 -0.8616 28.6238
OPM-2 GDSC1; GDSC2; CTRP2 -0.8333 0.173 -0.8333 34.3661
A3/Kawakami GDSC1; GDSC2; CTRP2 -0.8256 1.2847 -0.8345 34.3444
Raji GDSC1; GDSC2 -0.7115 0.9086 -0.7479 27.2993
Karpas-299 GDSC1; GDSC2 -0.6984 0.1214 -0.6989 26.9867
HAL-01 GDSC1; GDSC2 -0.6741 1.7706 -0.859 27.6884
HH [Human lymphoma] GDSC1; GDSC2; CTRP2 -0.6706 0.4312 -0.6707 33.2819
SKM-1 GDSC1; GDSC2 -0.6622 0.5364 -0.6705 26.6637
MC116 GDSC1; GDSC2 -0.6482 0.3809 -0.6515 26.4983
BV-173 GDSC1; GDSC2 -0.6168 1.6722 -0.7734 26.9719
QIMR-WIL GDSC1; GDSC2 -0.6163 1.4334 -0.7229 26.7074
NKM-1 GDSC1; GDSC2 -0.6107 1.2025 -0.6777 26.4478
OCI-Ly7 GDSC2 -0.6104 0.1529 -0.6107 26.1972
RCH-ACV GDSC2 -0.5447 0.6915 -0.5568 25.5971
ME1 GDSC1; GDSC2 -0.5165 0.066 -0.5165 25.1648
Jiyoye GDSC1; GDSC2 -0.4854 1.1651 -0.5384 25.1234
MOLT-3 CTRP2 -0.4751 0.2891 -0.4751 31.9782
RPMI-8226 GDSC1; GDSC2 -0.4712 1.7098 -0.6236 25.4983
BC-1 GDSC1; GDSC2 -0.4674 1.0368 -0.5037 24.8575
IM-9 GDSC1; GDSC2 -0.4521 0.0865 -0.4521 24.5211
A4/Fukuda GDSC1; GDSC2; CTRP2 -0.4354 0.324 -0.4354 31.7137
EB2 GDSC1; GDSC2 -0.4346 1.0796 -0.4737 24.5441
BE-13 GDSC1; GDSC2 -0.4302 2.2483 -0.7239 25.8342
JVM-3 GDSC1; GDSC2 -0.4265 1.6694 -0.5657 24.9832
P30/OHK GDSC1; GDSC2 -0.423 1.3556 -0.5003 24.6248
SUP-M2 GDSC1; GDSC2; CTRP2 -0.4155 0.9179 -0.416 31.5825
WSU-NHL GDSC1; GDSC2 -0.4053 1.5344 -0.5141 24.6122
YT GDSC1; GDSC2 -0.4022 0.2156 -0.4023 24.0222
PL-21 GDSC1; GDSC2 -0.3948 0.3494 -0.3954 23.9512
OCI-AML-3 GDSC1; GDSC2; CTRP2 -0.3796 0.1701 -0.3796 31.3415
MLMA GDSC1; GDSC2 -0.369 1.3382 -0.4394 24.0495
OCI-AML-5 GDSC1; GDSC2 -0.3676 0.541 -0.3703 23.6898
OCI-M1 GDSC1; GDSC2; CTRP2 -0.3538 0.7514 -0.3539 31.1703
RC-K8 GDSC1; GDSC2 -0.353 0.1817 -0.3531 23.5306
GA-10 GDSC1; GDSC2; CTRP2 -0.341 0.5068 -0.341 31.0846
Pfeiffer CTRP2 -0.3272 0.671 -0.3272 30.9923
MN-60 GDSC1; GDSC2 -0.3099 1.6959 -0.4448 23.7964
RL GDSC1; GDSC2; CTRP2 -0.3043 0.3236 -0.3043 30.8401
Reh GDSC1; GDSC2 -0.2952 1.1737 -0.337 23.1639
MHH-PREB-1 GDSC1; GDSC2 -0.2944 0.8715 -0.3083 23.0143
P31/FUJ GDSC1; GDSC2 -0.2835 0.256 -0.2836 22.8354
NOMO-1 GDSC1; GDSC2 -0.2704 1.3511 -0.3355 23.0363
ROS-50 GDSC1; GDSC2 -0.2492 0.4001 -0.2495 22.4934
EB1 CTRP2 -0.238 1.0966 -0.2386 30.3998
SUP-T1 GDSC1; GDSC2 -0.2292 1.9822 -0.428 23.3306
TUR GDSC1; GDSC2 -0.2141 1.4051 -0.2838 22.4974
TF-1 CTRP2 -0.1486 0.2989 -0.1486 29.8017
THP-1 GDSC1; GDSC2 -0.1127 1.6764 -0.2261 21.7131
Granta-519 GDSC1; GDSC2; CTRP2 -0.0696 1.5752 -0.0739 29.2896
OCI-Ly10 CTRP2 -0.0631 1.0831 -0.0633 29.2328
ST486 GDSC1; GDSC2; CTRP2 -0.0561 1.6502 -0.0616 29.2036
MOTN-1 CTRP2 -0.0235 1.9223 -0.0365 29.0114
HD-MY-Z CTRP2 0.0139 1.2495 0.0133 28.7205
KO52 CTRP2 0.1622 1.0805 0.1622 27.7298
HEL 92.1.7 CTRP2 0.192 1.2528 0.1918 27.532
Hs 611.T CTRP2 0.2333 1.2766 0.2331 27.2567
Namalwa GDSC1; GDSC2; CTRP2 0.3599 1.7654 0.3573 26.4208
EJM GDSC1; GDSC2; CTRP2 0.3718 1.766 0.3693 26.3414
SUP-B15 GDSC1; GDSC2; CTRP2 0.4057 1.6811 0.4044 26.1112
BL-70 CTRP2 0.411 1.3414 0.411 26.0715
Mino CTRP2 0.4485 1.2162 0.4485 25.8215
SET-2 CTRP2 0.7112 1.498 0.7111 24.0705
Ci-1 CTRP2 0.7198 1.2185 0.7198 24.0128
CA46 GDSC1; GDSC2; CTRP2 0.7727 2.4227 0.7595 23.7044
CMK CTRP2 0.8112 1.7561 0.811 23.4042
K-562 GDSC1; GDSC2; CTRP2 0.8943 2.108 0.8921 22.8568
MOLP-8 GDSC1; GDSC2; CTRP2 1.3357 2.2139 1.3352 19.9086
Kasumi-1 GDSC1; GDSC2; CTRP2 1.5536 3.6165 1.46 18.7745
HL-60 GDSC1; GDSC2; CTRP2 1.589 2.093 1.589 18.2182
RPMI-6666 GDSC1; GDSC2; CTRP2 1.5961 2.0559 1.5961 18.1713
Karpas-422 GDSC1; GDSC2; CTRP2 1.6216 2.0305 1.6216 18.001
SIG-M5 GDSC1; GDSC2; CTRP2 1.6792 1.9889 1.6792 17.6175
OCI-Ly3 CTRP2 1.7434 2.6474 1.7419 17.1944
HuNS1 CTRP2 1.7854 4.7709 1.4193 18.2105
OCI-Ly19 GDSC1; GDSC2; CTRP2 2.3773 3.9492 2.2886 13.268
BL-41 GDSC1; GDSC2; CTRP2 3.6241 11.9516 -0.089 19.3718
Toledo CTRP2 3.9188 14.9422 -1.3277 22.7778
⏷ Show the Full List of 185 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 1.6383 3.0847 1.6163 17.964
KYSE-150 GDSC2 -3.4957 -1.8918 -3.4965 68.4103
KYSE-270 GDSC2 -2.3554 -0.6935 -2.3602 54.3963
T.T GDSC2 -2.2455 -0.4527 -2.2544 53.0228
TE-9 GDSC1; GDSC2 -2.1435 -0.8349 -2.1446 41.44
TE-10 GDSC1; GDSC2 -2.0467 -1.1593 -2.0468 40.4676
KYSE-140 GDSC2 -1.8307 0.46 -1.8823 47.9739
TE-8 GDSC1; GDSC2 -1.756 0.0309 -1.7719 37.6364
KYSE-180 GDSC2 -1.6653 0.1214 -1.6831 45.8791
TE-1 GDSC1; GDSC2 -1.5055 0.6645 -1.5607 35.3215
KYSE-410 GDSC2 -1.3483 1.7894 -1.5988 42.8138
KYSE-510 GDSC2 -0.8271 0.1777 -0.829 28.3798
COLO 680N GDSC2 -0.7965 2.8538 -1.3213 37.6078
TE-4 GDSC2 -0.7418 2.7169 -1.2147 36.7643
TE-5 GDSC1; GDSC2; CTRP2 -0.3939 2.4537 -0.4603 31.6584
TE-15 GDSC1; GDSC2 -0.2779 1.7487 -0.4221 23.5257
TE-6 GDSC1; GDSC2 0.0482 2.0808 -0.1527 20.5754
KYSE-520 GDSC2; CTRP2 0.2833 2.2398 0.2644 26.9858
KYSE-70 GDSC2 0.3001 4.524 -0.8575 28.6665
TE-11 GDSC2; CTRP2 0.7821 2.2471 0.7755 23.6197
OE21 GDSC2; CTRP2 0.8188 2.0842 0.8162 23.3616
OE33 GDSC2; CTRP2 1.2479 2.3142 1.2461 20.4984
KYSE-450 GDSC2; CTRP2 1.3053 2.236 1.3046 20.1118
OE19 GDSC2; CTRP2 1.3405 2.7688 1.3274 19.9192
EC-GI-10 GDSC1; GDSC2; CTRP2 1.6156 3.2471 1.5778 18.1688
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 1.6014 2.6416 1.5984 18.1458
Panc 10.05 GDSC2 -2.5257 0.7431 -2.6613 55.7201
HuP-T4 GDSC2 -2.0185 -0.0526 -2.0383 50.2258
KP-1N GDSC2 -1.9443 0.4673 -2.0031 49.3393
BxPC-3 GDSC2 -1.77 0.305 -1.8042 47.2074
CFPAC-1 GDSC2 -1.5229 1.454 -1.7104 44.6381
HPAC GDSC2 -1.507 2.0307 -1.8357 44.7979
HPAF-II GDSC2 -1.0965 1.6957 -1.3013 39.7064
QGP-1 GDSC2 -1.0385 1.2109 -1.1386 30.9944
PaTu 8902 GDSC2 -1.0139 2.1983 -1.3454 39.2695
Panc 08.13 GDSC2 -0.994 2.3874 -1.3809 39.2654
Hs 766T GDSC2 -0.9517 3.2865 -1.6456 39.9221
YAPC GDSC2 -0.7989 2.5733 -1.2283 37.22
PL4 GDSC2 -0.5277 1.9418 -0.7428 32.8973
SU.86.86 GDSC2 -0.5052 2.1639 -0.7805 32.9691
PaTu 8988t GDSC2; CTRP2 -0.2316 0.3576 -0.2316 30.3549
KP-3 GDSC2 -0.1478 2.6224 -0.5393 29.3321
Capan-2 GDSC2 -0.038 3.633 -0.8134 30.2973
KP-4 GDSC2 0.0237 2.5289 -0.3213 26.9506
SUIT-2 GDSC2 0.2916 3.0054 -0.2104 24.7148
PSN1 GDSC1; GDSC2; CTRP2 0.3695 1.6747 0.368 26.3529
DAN-G GDSC2; CTRP2 0.4961 2.4119 0.4747 25.5758
HuP-T3 GDSC2; CTRP2 0.6423 1.9716 0.6395 24.5388
MIA PaCa-2 GDSC2; CTRP2 0.7033 1.8086 0.7025 24.1257
Capan-1 GDSC2; CTRP2 0.8685 2.6593 0.8453 23.0992
MZ-PC-1 GDSC1; GDSC2 0.9433 3.035 0.4613 13.2778
PaTu 8988s CTRP2 1.0037 3.0396 0.9535 22.2897
SW1990 GDSC2; CTRP2 1.2393 2.1424 1.2389 20.5509
KP-2 GDSC2; CTRP2 1.4709 2.2324 1.4708 19.0062
Panc 03.27 GDSC2; CTRP2 1.6039 2.1186 1.6039 18.1191
PK-45H CTRP2 1.6537 4.3229 1.4097 18.641
Panc 02.03 GDSC2; CTRP2 1.6885 2.4614 1.6881 17.5567
Panc 04.03 GDSC2; CTRP2 1.8484 3.5603 1.7858 16.7019
AsPC-1 GDSC2; CTRP2 2.3152 5.0458 1.8989 14.8807
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 -0.0329 1.3816 -0.0344 33.4412
SH-4 GDSC1; GDSC2 -3.6588 -1.7691 -3.6611 56.5444
G-361 GDSC2 -3.2933 -1.3661 -3.2975 65.7024
LB2518-MEL GDSC1; GDSC2 -3.0329 -1.3724 -3.0349 50.3285
MMAc-SF GDSC1; GDSC2 -2.981 -0.7435 -2.9962 49.8131
A-388 GDSC1; GDSC2 -2.9628 -1.4775 -2.9637 49.6283
Hs 940.T GDSC2 -2.5409 -1.2092 -2.5416 45.5714
G-mel GDSC2 -2.5307 -1.613 -2.5307 45.4656
A-431 GDSC2 -2.5199 -1.1812 -2.5206 45.3606
MZ-MEL-2 GDSC1; GDSC2 -2.5148 -0.5368 -2.5267 45.1875
Hs 938.T GDSC2 -2.4554 -1.1827 -2.4559 44.7122
M14 GDSC2 -2.4234 -0.6099 -2.4311 55.2062
CP50-MEL-B GDSC2 -2.3623 -0.6991 -2.3671 43.7958
SK-MEL-28 GDSC2 -2.3321 -0.8625 -2.3341 43.4815
CP66-MEL GDSC1; GDSC2 -2.3271 -0.8763 -2.329 43.2789
GAK GDSC1; GDSC2 -2.3078 -1.316 -2.3078 43.0779
COLO 679 GDSC2 -2.3019 -0.7138 -2.3056 53.7429
IGR-37 GDSC2 -2.261 -0.7261 -2.2642 53.2413
WM793 GDSC2 -2.1321 -0.2385 -2.1462 51.6192
RPMI-7951 GDSC2 -2.018 -0.381 -2.0247 50.2229
WM35 GDSC2 -2.0122 0.0296 -2.0367 50.1487
LB373-MEL-D GDSC1; GDSC2 -1.969 -0.5535 -1.9717 39.7033
HMV-II GDSC2 -1.806 1.7121 -2.0787 47.9446
WM278 GDSC2 -1.4298 0.901 -1.5103 43.2076
IPC-298 GDSC2 -1.4181 0.0241 -1.4252 34.3366
IST-MEL1 GDSC1; GDSC2 -1.4158 0.2226 -1.4309 34.2329
WM1552C GDSC2 -1.3588 0.9203 -1.4372 42.337
CHL-1 GDSC2 -1.3105 1.7959 -1.5592 42.3744
VMRC-MELG GDSC2 -1.2736 0.3098 -1.2888 32.9272
MZ-MEL-7 GDSC1; GDSC2 -1.205 0.4266 -1.2246 32.1482
DJM-1 GDSC1; GDSC2 -1.1075 0.9021 -1.1667 31.3712
A-375 GDSC2 -1.0772 0.0214 -1.0793 30.8906
SK-MEL-30 GDSC2 -1.0524 0.0441 -1.0546 30.6425
Mel Ho GDSC2 -0.9229 0.2866 -0.9283 29.3589
Mel JuSo GDSC2 -0.8376 1.0742 -0.9019 35.8505
451Lu GDSC2 -0.5188 0.7201 -0.5316 25.3411
A101D GDSC1; GDSC2; CTRP2 -0.4121 0.4119 -0.4121 31.5581
SK-MEL-31 GDSC2 -0.3819 0.389 -0.3827 23.9063
COLO 783 GDSC2 -0.37 1.3467 -0.4418 24.1514
SK-MEL-5 GDSC2 -0.3572 1.4706 -0.4497 24.1309
COLO 829 GDSC1; GDSC2; CTRP2 -0.3421 4.0053 -0.6852 32.2139
RVH-421 GDSC2; CTRP2 -0.2862 0.9199 -0.2864 30.7198
WM115 GDSC2; CTRP2 -0.2403 0.2949 -0.2403 30.413
WT2-iPS GDSC2; CTRP2 -0.2166 0.2782 -0.2166 30.2551
Hs 294T CTRP2 -0.1339 0.6689 -0.1339 29.7037
COLO 800 GDSC1; GDSC2; CTRP2 -0.1256 4.036 -0.4568 30.753
SK-MEL-1 GDSC1; GDSC2 0.041 2.2028 -0.1965 20.8464
COLO 792 GDSC2; CTRP2 0.0534 1.3041 0.0528 28.4571
K029AX CTRP2 0.0571 0.7617 0.0571 28.4305
HT-144 GDSC1; GDSC2; CTRP2 0.2577 1.7174 0.2548 27.1028
MeWo GDSC2; CTRP2 0.3307 2.0342 0.3217 26.6369
IGR-1 GDSC2; CTRP2 0.3816 1.6423 0.3804 26.2715
LOX-IMVI GDSC1; GDSC2; CTRP2 0.4942 2.6944 0.4513 25.6612
WM88 CTRP2 0.5877 1.9619 0.5845 24.9044
HMCB CTRP2 0.8487 1.9213 0.8479 23.1561
UACC-257 GDSC1; GDSC2; CTRP2 0.8608 3.8595 0.6601 23.7645
SK-MEL-2 GDSC1; GDSC2; CTRP2 1.0968 2.6874 1.0801 21.5557
CJM [Human melanoma] CTRP2 1.1903 2.1326 1.1897 20.8782
SK-MEL-3 GDSC2; CTRP2 1.239 2.9294 1.2115 20.6442
A2058 GDSC2; CTRP2 1.2958 2.109 1.2956 20.1735
WM266-4 CTRP2 1.3258 2.583 1.3197 19.9935
WM983B CTRP2 1.4136 3.3666 1.3486 19.6084
SK-MEL-24 GDSC2; CTRP2 1.616 4.1063 1.4248 18.7025
UACC-62 GDSC2; CTRP2 1.6632 2.0685 1.6632 17.724
Hs 895.T CTRP2 1.9239 3.0633 1.9138 16.0199
IGR-39 CTRP2 2.0424 3.4669 2.005 15.3226
Hs 839.T CTRP2 3.8199 4.5148 3.7114 3.7391
EquiPSC Line K2 GDSC2 -1.4108 0.7481 -1.47 34.5166
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-220 GDSC2 -2.1889 -0.2006 -2.2064 52.3042
FLO-1 GDSC2 -2.0386 0.4099 -2.0965 50.4563
OACM5.1 C GDSC2 -1.6397 0.7462 -1.7132 45.7206
OACP4 C GDSC2 -1.5415 0.6739 -1.5999 44.4881
HCE-4 GDSC2 -1.374 0.1774 -1.3857 33.9167
SK-GT-4 GDSC2 -1.2923 1.7086 -1.5178 42.0862
ESO-51 GDSC2 -1.0933 1.4722 -1.2477 39.4461
KYSE-50 GDSC2 -0.964 1.0782 -1.0376 37.4678
KYAE-1 GDSC2 -0.9014 0.7178 -0.9296 36.4365
TE-12 GDSC1; GDSC2 -0.2815 2.2024 -0.5479 24.2129
ESO-26 GDSC2 -0.1169 1.9536 -0.2978 27.6231
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 1.0189 4.1293 0.7679 22.8903
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Kelly GDSC1; GDSC2 -2.4522 -1.8668 -2.4522 44.522
SK-N-MC-IXC GDSC2 -2.3818 -1.9148 -2.3818 43.9714
NB69 GDSC1; GDSC2 -2.1963 -0.6966 -2.1992 41.9757
CHP-126 GDSC1; GDSC2 -2.154 -0.891 -2.1549 41.5444
CHP-134 GDSC2 -1.9279 -0.2694 -1.9361 49.1077
NB1 GDSC1; GDSC2 -1.7369 -0.0953 -1.7469 37.4171
LA-N-6 GDSC1; GDSC2 -1.6745 0.0683 -1.6898 36.8193
SJNB-17 GDSC1; GDSC2 -1.5471 0.3344 -1.5739 35.6018
SJNB-7 GDSC1; GDSC2 -1.5373 0.648 -1.5925 35.6379
GI-ME-N GDSC1; GDSC2 -1.375 0.4925 -1.4065 33.9055
SJNB-12 GDSC1; GDSC2 -1.3701 1.2784 -1.509 34.3661
SJNB-13 GDSC1; GDSC2 -1.289 1.3966 -1.4444 33.6413
SK-N-BE(2)-M17 GDSC1; GDSC2 -1.2564 0.834 -1.3166 32.8618
KP-N-RT-BM-1 GDSC2 -0.685 1.0151 -0.7317 27.1818
TGW GDSC1; GDSC2 -0.6287 1.1226 -0.6856 26.5759
SJNB-5 GDSC1; GDSC2 -0.612 0.4318 -0.6159 26.1397
NB(TU)1 GDSC1; GDSC2 -0.5059 1.1608 -0.5597 25.3326
SiMa GDSC1; GDSC2 -0.4969 1.5217 -0.6109 25.5541
IMR-5 GDSC1; GDSC2 -0.486 1.6137 -0.6182 25.5403
SJNB-14 GDSC1; GDSC2 -0.4267 0.238 -0.4269 24.2683
CHP-212 GDSC2; CTRP2 -0.4174 1.5165 -0.4255 31.6207
SK-N-AS GDSC2; CTRP2 -0.4049 0.2417 -0.4049 31.5105
SJNB-10 GDSC1; GDSC2 -0.3175 1.4717 -0.407 23.6345
KP-N-YS GDSC1; GDSC2 -0.2935 1.6805 -0.4236 23.6074
GOTO GDSC1; GDSC2 -0.2876 1.9061 -0.4715 23.8336
NH-12 GDSC1; GDSC2 -0.2406 1.4476 -0.3196 22.811
SJNB-6 GDSC1; GDSC2 -0.1668 0.9982 -0.1843 21.7566
MHH-NB-11 GDSC1; GDSC2 -0.1279 0.7542 -0.1318 21.2985
SK-N-FI GDSC1; GDSC2; CTRP2 -0.0988 1.8266 -0.1101 29.5077
SK-N-DZ GDSC1; GDSC2; CTRP2 0.2782 1.3914 0.2779 26.9576
SK-N-SH GDSC2; CTRP2 0.7159 1.8118 0.7152 24.0411
NH-6 CTRP2 1.2822 2.4593 1.2785 20.2763
KP-N-YN GDSC1; GDSC2; CTRP2 5.8535 12.6218 1.3689 9.6611
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 -2.8947 -1.1942 -2.8975 61.0282
SNU-869 CTRP2 1.931 3.4782 1.8853 16.0931
Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OCUB-M GDSC1; GDSC2 -3.6038 -1.9621 -3.6046 56.0213
HCC70 GDSC2 -3.2617 -1.9372 -3.2619 65.6927
COLO 824 GDSC1; GDSC2 -2.5909 -0.3143 -2.6153 45.9758
HCC1937 GDSC2 -2.4749 -0.3978 -2.4914 55.7591
Evsa-T GDSC1; GDSC2 -2.4581 -0.8601 -2.4612 44.5929
MDA-MB-231 GDSC2 -2.409 -0.5506 -2.4182 55.0197
MDA-MB-436 GDSC2 -2.3655 -0.0963 -2.3952 54.3786
HCC1187 GDSC1; GDSC2 -2.3139 -0.0357 -2.3458 43.2568
HCC1569 GDSC2 -2.2689 -0.4155 -2.2795 42.8821
CAL-51 GDSC2 -2.2131 -0.1095 -2.2363 52.5824
AU565 GDSC2 -2.2112 0.2199 -2.2594 52.5012
MCF-7 GDSC2 -2.1664 1.509 -2.4229 51.7309
CAL-120 GDSC2 -2.0899 0.4155 -2.1514 51.0584
CAMA-1 GDSC2 -2.0897 0.0801 -2.1207 51.0833
HCC2157 GDSC1; GDSC2 -2.0807 -1.1665 -2.0808 40.8075
EFM-19 GDSC2 -2.003 0.3707 -2.0548 50.0355
JIMT-1 GDSC2 -1.9634 -0.1613 -1.9764 49.5498
MDA-MB-157 GDSC2 -1.6842 0.3343 -1.7169 46.155
HCC1954 GDSC2 -1.6673 0.3549 -1.7009 45.9501
T-47D GDSC2 -1.6212 0.582 -1.674 45.4413
HCC1806 GDSC2 -1.3553 0.5199 -1.3881 42.1024
MDA-MB-175-VII GDSC2 -1.3487 2.1786 -1.7048 43.1301
HDQ-P1 GDSC2 -1.326 0.8871 -1.3976 41.9094
MDA-MB-453 GDSC2 -1.3214 1.9737 -1.6175 42.6492
HCC1500 GDSC1; GDSC2; CTRP2 -1.1859 2.6896 -1.3348 37.1694
MRK-nu-1 GDSC1; GDSC2 -0.9201 0.244 -0.9243 29.222
HCC1143 GDSC2 -0.8738 1.8944 -1.1081 37.1881
MDA-MB-415 GDSC2 -0.7016 0.7958 -0.727 33.927
DU4475 GDSC1; GDSC2; CTRP2 -0.6651 0.3852 -0.6651 33.2452
MFM-223 GDSC1; GDSC2 -0.4273 0.2342 -0.4275 24.2743
CAL-148 GDSC1; GDSC2 -0.3091 1.9306 -0.5014 24.0927
UACC-812 GDSC1; GDSC2 -0.2696 2.3598 -0.5837 24.3503
HCC1395 GDSC2 -0.2365 2.7466 -0.6788 30.703
HCC1599 GDSC1; GDSC2 -0.2349 0.7131 -0.2397 22.3727
Hs 578T GDSC2; CTRP2 -0.1924 3.2321 -0.3557 30.6401
HCC2218 GDSC1; GDSC2 -0.1608 2.2433 -0.4288 23.021
MDA-MB-361 GDSC2 -0.1562 3.1345 -0.7372 30.5594
BT-549 GDSC2; CTRP2 -0.0043 3.0615 -0.1246 29.2451
MDA-MB-468 GDSC2; CTRP2 0.0722 1.1348 0.072 28.3306
CAL-85-1 GDSC2; CTRP2 0.099 1.9498 0.0879 28.1885
HCC202 GDSC2; CTRP2 0.1155 2.4035 0.0795 28.162
HCC38 GDSC2; CTRP2 0.2107 1.5033 0.2096 27.4101
EFM-192A GDSC2; CTRP2 0.3063 3.4844 0.1365 27.3471
YMB-1-E GDSC2 0.3774 2.3701 0.1159 17.6884
HCC1419 GDSC2; CTRP2 0.514 3.5625 0.3462 25.9583
MDA-MB-330 GDSC2 0.9894 4.6613 -0.2445 17.3713
BT-474 GDSC1; GDSC2 1.4833 5.0281 0.0364 13.9268
BT-20 GDSC2; CTRP2 1.6253 2.2047 1.6253 17.9763
UACC-893 GDSC2 1.705 4.9129 0.291 11.6905
BT-483 GDSC2 2.0906 6.2788 -0.0643 15.6162
ZR-75-30 GDSC2; CTRP2 2.2741 6.7771 1.1433 17.9096
HCC1428 GDSC2; CTRP2 3.2667 9.5442 0.7865 16.8979
BT164 CTRP2 -1.6639 -0.8145 -1.6639 39.9036
BT 145 CTRP2 -1.41 -0.6543 -1.41 38.2106
BT 112 CTRP2 -1.1505 -0.4926 -1.1505 36.4812
BT 224 CTRP2 0.1532 2.7607 0.0844 28.0219
BT 179 CTRP2 0.2279 2.5711 0.1829 27.4433
⏷ Show the Full List of 57 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 60 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PFSK-1 GDSC2 -3.0588 -1.2667 -3.0621 62.9829
ONS-76 GDSC1; GDSC2 -3.0251 -1.611 -3.0256 50.2504
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 -2.9428 0.6526 -3.0951 49.4792
D-542MG GDSC1; GDSC2 -2.7752 -0.822 -2.7834 47.7684
MOG-G-CCM GDSC2 -2.6154 -0.7605 -2.6225 57.5474
SW1088 GDSC2 -2.5288 -0.5542 -2.5404 56.4487
GaMG GDSC2 -2.4727 -1.1438 -2.4734 55.8912
KNS-81-FD GDSC1; GDSC2 -2.3602 0.54 -2.4539 43.8962
D-392MG GDSC1; GDSC2 -2.3457 -0.939 -2.3471 43.4631
Onda 10 GDSC1; GDSC2 -2.329 0.0479 -2.3679 43.4292
D-263MG GDSC1; GDSC2 -2.3157 -1.7707 -2.3157 43.157
LN-18 GDSC2 -2.303 -0.5003 -2.3116 53.7284
MOG-G-UVW GDSC2 -2.2702 -0.3887 -2.2818 53.3135
KINGS-1 GDSC1; GDSC2 -2.1817 0.8237 -2.3046 42.2521
M059J GDSC2 -2.1756 -0.2906 -2.1887 52.1532
SK-MG-1 GDSC2 -2.0544 -0.0451 -2.0759 50.6632
H4 GDSC2 -1.8574 0.1279 -1.8823 48.2599
LN-229 GDSC2 -1.802 0.4987 -1.8561 47.6319
Daoy GDSC2 -1.7325 0.0293 -1.7476 46.7023
CAS-1 GDSC1; GDSC2 -1.727 2.3139 -2.1572 38.9492
SF126 GDSC1; GDSC2 -1.6331 -0.722 -1.6332 36.3316
GB-1 GDSC1; GDSC2 -1.6238 0.6196 -1.6809 36.5078
KALS-1 GDSC1; GDSC2 -1.5991 1.0098 -1.7085 36.4968
LNZTA3WT4 GDSC2 -1.5647 0.0412 -1.5757 44.6067
KNS-42 GDSC1; GDSC2; CTRP2 -1.4629 -0.8961 -1.4629 38.5636
D-245MG GDSC2 -1.4625 0.5532 -1.5037 34.9475
42-MG-BA GDSC2 -1.4606 0.356 -1.4854 43.3712
SF295 GDSC2 -1.4399 -0.1742 -1.4429 34.5348
D-247MG GDSC1; GDSC2 -1.3145 2.0252 -1.6242 34.5863
GI-1 GDSC1; GDSC2 -1.1791 1.2556 -1.2982 32.379
SF268 GDSC1; GDSC2 -1.1547 0.585 -1.1837 31.692
U-251MG GDSC2 -1.1148 0.7282 -1.1548 39.1569
D-336MG GDSC1; GDSC2 -1.0602 0.7113 -1.0956 30.7794
D-423MG GDSC2 -1.0374 1.394 -1.1712 31.1508
SNB-75 GDSC1; GDSC2 -0.5365 0.6353 -0.5456 25.4106
AM-38 GDSC1; GDSC2 -0.5267 1.7665 -0.6974 26.1473
DK-MG GDSC2; CTRP2 -0.5075 0.1645 -0.5075 32.1947
LN-405 GDSC2 -0.4931 1.7273 -0.6514 32.1377
D-566MG GDSC2 -0.3974 0.6591 -0.4039 24.0908
SF539 GDSC1; GDSC2 -0.3781 0.1228 -0.3781 23.7813
Hs 683 GDSC2; CTRP2 -0.3411 0.983 -0.3416 31.087
A-172 GDSC2; CTRP2 -0.3076 0.9516 -0.3079 30.8629
D283 Med GDSC1; GDSC2; CTRP2 -0.3045 0.5231 -0.3045 30.8411
U-87MG ATCC GDSC1; GDSC2 -0.1816 1.8523 -0.3422 22.6521
DBTRG-05MG GDSC2 0.0168 2.6877 -0.3847 27.3982
GOS-3 CTRP2 0.021 1.5141 0.0186 28.6793
U-118MG GDSC2; CTRP2 0.2474 2.0005 0.2378 27.194
YKG-1 GDSC2; CTRP2 0.2647 2.3475 0.2388 27.1338
Onda 11 GDSC1; GDSC2 0.2885 2.4768 -0.0167 18.755
D-502MG GDSC1; GDSC2 0.4455 3.6261 -0.3084 19.7573
TM-31 CTRP2 0.9808 1.9992 0.9801 22.2754
M059K CTRP2 1.0694 1.8975 1.0693 21.6826
T98G GDSC2; CTRP2 1.3072 2.4416 1.3042 20.107
NMC-G1 GDSC1; GDSC2 1.3446 4.5815 0.1293 13.8235
GMS-10 CTRP2 1.386 2.2742 1.3855 19.5734
YH-13 GDSC2; CTRP2 1.5309 2.0647 1.5309 18.606
8-MG-BA GDSC1; GDSC2; CTRP2 1.6363 2.2015 1.6363 17.9033
CCF-STTG1 CTRP2 1.7039 2.6204 1.7024 17.4576
Becker GDSC1; GDSC2; CTRP2 1.8095 3.3199 1.7749 16.8655
SW1783 GDSC2; CTRP2 3.5659 10.041 0.8102 16.1425
⏷ Show the Full List of 60 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC1; GDSC2 -0.4999 1.9044 -0.7027 26.0483
ETK-1 GDSC1; GDSC2 -0.1067 1.909 -0.2749 21.9446
TGBC24TKB GDSC2 3.7188 6.4827 0.9771 3.5645
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-280 GDSC2 -2.0827 0.0848 -2.1136 50.9981
RL95-2 GDSC1; GDSC2 -0.7716 0.5573 -0.7838 27.777
KLE GDSC2 -0.7189 2.6521 -1.1678 36.3922
MFE-296 GDSC2 -0.3075 2.0704 -0.5378 30.2891
JHUEM-1 CTRP2 -0.0577 0.3356 -0.0577 29.1956
MFE-319 GDSC2; CTRP2 0.2166 1.2547 0.2165 27.3677
JHUEM-3 CTRP2 0.4449 2.5583 0.4113 25.9583
EN GDSC2; CTRP2 0.6199 2.5925 0.5913 24.7749
AN3-CA GDSC2; CTRP2 1.0979 2.1875 1.0964 21.4973
ESS-1 GDSC2; CTRP2 1.2555 2.0338 1.2554 20.442
JHUEM-7 CTRP2 1.3137 2.439 1.3108 20.0633
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KTCTL-195 GDSC2 -2.4552 -0.999 -2.4568 55.6611
A-704 GDSC2 -2.4144 -0.5375 -2.4241 55.0816
KTCTL-140 GDSC2 -2.2876 -0.5625 -2.2942 43.0537
SW13 GDSC2 -2.1085 0.0506 -2.1381 51.3106
LB2241-RCC GDSC1; GDSC2 -2.0234 -0.0974 -2.0411 40.3134
TK-10 GDSC1; GDSC2 -1.8358 0.2574 -1.8692 38.5116
BB65-RCC GDSC1; GDSC2 -1.7248 -0.1769 -1.7319 37.2831
BFTC-909 GDSC2 -1.6016 0.4387 -1.6393 45.1565
KMRC-20 GDSC2 -1.5722 0.6499 -1.6297 44.8591
NCC010 GDSC2 -1.1364 0.8368 -1.1894 31.7395
RXF 393L GDSC1; GDSC2 -1.1026 0.3598 -1.1151 31.0885
769-P GDSC2 -1.1022 1.8295 -1.3405 39.9137
NCC021 GDSC2 -0.8556 0.9067 -0.9 28.8809
UO-31 GDSC2 -0.8538 0.7954 -0.8866 28.804
KTCTL-13 GDSC2 -0.8487 0.9282 -0.8951 28.8215
KTCTL-21 GDSC2 -0.7077 1.5806 -0.8519 27.9111
KTCTL-1M GDSC2 -0.4153 1.3508 -0.4912 24.6267
VMRC-RCW GDSC2 -0.389 0.69 -0.3965 24.0118
LB996-RCC GDSC1; GDSC2 -0.3627 1.3258 -0.4306 23.9736
SN12C GDSC2 -0.3613 1.8565 -0.5392 30.6296
OS-RC-2 GDSC1; GDSC2 -0.2714 1.8615 -0.4424 23.6032
LB1047-RCC GDSC1; GDSC2 -0.1636 1.2699 -0.2093 21.8685
RCC10RGB GDSC1; GDSC2 -0.1323 2.8604 -0.608 23.8658
786-O GDSC2; CTRP2 0.0773 1.8468 0.0691 28.3233
KTCTL-26A GDSC2 0.1274 1.721 0.0252 19.3224
SW156 GDSC2 0.2397 2.6865 -0.1442 19.7489
KMRC-1 GDSC2; CTRP2 0.3948 1.5419 0.3942 26.1814
HA7-RCC GDSC1; GDSC2 0.4223 2.9303 -0.0421 18.326
VMRC-RCZ GDSC2; CTRP2 1.0344 2.5309 1.0235 21.9522
CAL-54 GDSC2; CTRP2 1.0496 2.4367 1.0426 21.8377
KMRC-2 CTRP2 1.5934 2.1713 1.5933 18.1895
ACHN GDSC2; CTRP2 1.9205 3.5784 1.8604 16.2131
Caki-1 GDSC2; CTRP2 2.3321 4.5585 2.0814 14.1521
A-498 GDSC1; GDSC2; CTRP2 4.2008 9.3299 1.7163 11.1689
Caki-2 CTRP2 4.8122 12.0886 0.8392 13.5241
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RKO GDSC1; GDSC2 -3.1048 -1.4653 -3.1064 51.0452
SK-CO-1 GDSC2 -3.0041 -1.1624 -3.0084 62.2883
SW626 GDSC2 -2.9143 -1.0979 -2.9186 61.2111
HCT 116 GDSC2 -2.8425 -1.4197 -2.8432 60.4742
DiFi GDSC2 -2.4394 -0.4491 -2.4528 55.3561
SNU-407 GDSC2 -2.402 -0.3189 -2.4201 54.8751
SNU-1040 GDSC2 -2.3217 -0.618 -2.3276 53.9744
SW48 GDSC2 -2.1911 -0.2929 -2.2045 52.3427
SNU-C2B GDSC2 -2.1451 1.0582 -2.3057 51.5941
CCK-81 GDSC2 -2.0996 -0.2433 -2.1127 51.2229
KM12 GDSC1; GDSC2 -2.0875 -0.4704 -2.0932 40.9013
LoVo GDSC2 -2.0714 0.6042 -2.1545 50.828
CaR-1 GDSC2 -2 0.0376 -2.0246 50.0006
HT-55 GDSC2 -1.9518 -0.0446 -1.9699 49.4091
HCC2998 GDSC1; GDSC2 -1.8808 -0.8602 -1.881 38.8088
GP5d GDSC2 -1.8192 0.3411 -1.8589 47.8169
SNU-C5 GDSC2 -1.7998 0.5534 -1.8597 47.6143
NCI-H747 GDSC1; GDSC2 -1.5314 1.0394 -1.6406 35.8262
SW620 GDSC2 -1.425 -0.2117 -1.4272 34.3815
C2BBe1 GDSC1; GDSC2; CTRP2 -1.382 1.3137 -1.4052 38.0975
SW1463 GDSC2 -1.376 1.1381 -1.4898 42.6797
LS180 GDSC2 -1.3207 0.7126 -1.3705 41.751
HT-29 GDSC2 -1.2568 0.6214 -1.2939 32.867
SNU-175 GDSC2 -1.0705 0.9459 -1.133 38.7259
HT115 GDSC2 -1.053 0.2582 -1.0601 30.6732
SW837 GDSC2 -0.9786 1.8587 -1.2132 38.4381
LS411N GDSC1; GDSC2 -0.9566 2.5389 -1.3883 31.6815
COLO205 GDSC2 -0.8286 1.335 -0.9341 35.9702
NCI-H508 GDSC2 -0.7632 0.2318 -0.7653 27.7396
LS513 GDSC1; GDSC2 -0.7429 0.6426 -0.759 27.5096
SW1116 GDSC2 -0.6184 2.0579 -0.8736 34.2257
CL-11 GDSC1; GDSC2 -0.5513 1.871 -0.7502 26.5394
MDST8 GDSC1; GDSC2 -0.4737 0.0549 -0.4737 24.7371
LS123 GDSC1; GDSC2 -0.417 2.1148 -0.6699 25.4878
CW-2 GDSC1; GDSC2 -0.417 2.3164 -0.7305 25.808
SNU-283 GDSC2 -0.4158 1.19 -0.4675 24.5064
T84 GDSC2 -0.4148 1.9364 -0.6182 31.4443
SNU-81 GDSC2 -0.3586 0.5096 -0.3606 23.6792
SNU-61 GDSC2 -0.2559 2.0223 -0.4681 29.5423
COLO 320HSR GDSC1; GDSC2 -0.2341 1.9589 -0.4271 23.3485
SNU-C1 GDSC1; GDSC2; CTRP2 0.0804 1.485 0.0788 28.2807
NCI-H716 GDSC1; GDSC2; CTRP2 0.1733 1.813 0.1676 27.6751
SW948 GDSC2; CTRP2 0.5676 1.7833 0.5663 25.0318
SW1417 GDSC2; CTRP2 0.789 4.1713 0.5065 24.5303
HCT 15 GDSC2; CTRP2 0.8587 1.838 0.8583 23.0881
RCM-1 [Human ESC] GDSC2; CTRP2 1.1343 4.6363 0.7525 22.5918
HCC-56 CTRP2 1.3891 2.3519 1.388 19.5547
COLO 678 GDSC2; CTRP2 1.4786 3.7729 1.3497 19.3973
SNU-503 CTRP2 1.6222 3.9452 1.4693 18.5254
GP2d CTRP2 1.7166 3.1696 1.6913 17.453
LS1034 GDSC1; GDSC2; CTRP2 2.4489 3.5291 2.4276 12.5578
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 -1.02 0.6176 -1.0454 30.3275
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HLE GDSC2 -2.3554 -0.1038 -2.3842 54.2637
JHH-7 GDSC2 -1.7955 0.1193 -1.8176 47.4958
Hep 3B2.1-7 GDSC2 -0.8793 1.6237 -1.0481 29.7499
SNU-398 GDSC2 -0.7682 2.302 -1.1086 36.4506
Hep-G2/C3A GDSC2 -0.4969 1.8213 -0.6783 32.3219
HLF CTRP2 -0.1259 0.6 -0.1259 29.6504
JHH-1 GDSC2; CTRP2 0.0896 0.8321 0.0896 28.2137
JHH-4 GDSC2; CTRP2 0.6853 2.2062 0.6781 24.2667
Huh-7 GDSC2 0.9491 4.0441 0.0095 19.8445
JHH-5 CTRP2 0.9898 2.8979 0.9532 22.3363
JHH-2 GDSC2; CTRP2 1.0489 2.2085 1.0468 21.8258
PLC/PRF/5 CTRP2 1.1437 2.4817 1.1371 21.2092
SNU-423 GDSC2; CTRP2 1.2292 2.371 1.2265 20.6258
SNU-387 GDSC2; CTRP2 1.2386 4.157 1.0006 21.3821
SK-HEP-1 GDSC2; CTRP2 1.5273 2.0377 1.5273 18.6301
SNU-449 GDSC2; CTRP2 1.8946 2.8817 1.8906 16.1948
SNU-475 CTRP2 2.2955 3.3161 2.2838 13.5479
JHH-6 GDSC2; CTRP2 2.8777 5.3827 2.3682 11.5142
HuH-1 GDSC2; CTRP2 3.0684 8.5272 1.101 16.1142
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 200 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1975 GDSC1; GDSC2 -3.0867 -1.0645 -3.094 50.8594
NCI-H2818 GDSC2 -2.744 -1.3224 -2.7448 59.2523
ABC-1 GDSC2 -2.7006 -0.9931 -2.7043 47.1804
NCI-H2085 GDSC2 -2.6986 -1.2399 -2.6997 58.6825
SBC-3 GDSC2 -2.5726 -1.2078 -2.5734 57.1311
LXF 289 GDSC1; GDSC2 -2.5189 0.0303 -2.5652 45.3204
HARA [Human squamous cell lung carcinoma] GDSC2 -2.4813 -1.2327 -2.4817 56.0039
HCC44 GDSC2 -2.4707 -0.7934 -2.475 55.8172
NCI-H69 GDSC1; GDSC2 -2.4672 0.0391 -2.5118 44.8084
LOU-NH91 GDSC2 -2.3967 -0.4247 -2.4099 54.841
NCI-H2795 GDSC2 -2.3323 0.3964 -2.4059 53.831
NCI-H847 GDSC1; GDSC2 -2.3131 -1.1785 -2.3134 43.1325
COR-L311 GDSC2 -2.3044 -0.5254 -2.3123 53.7495
NCI-H292 GDSC2 -2.2811 -0.8116 -2.2833 42.9714
NCI-H2731 GDSC2 -2.2745 0.0905 -2.3143 53.2668
NCI-H1651 GDSC2 -2.2348 -0.3458 -2.2472 52.8788
NCI-H446 GDSC1; GDSC2 -2.207 0.1921 -2.2524 42.2452
EBC-1 GDSC2 -2.1745 0.0594 -2.2074 52.0968
NCI-H2171 GDSC1; GDSC2 -2.1671 -0.025 -2.1938 41.781
COR-L279 GDSC2 -2.1124 -0.3275 -2.1226 51.3845
LCLC-103H GDSC2 -2.1105 0.0661 -2.1413 51.3334
EMC-BAC-2 GDSC2 -2.0218 0.6776 -2.1115 50.2527
NCI-H209 GDSC1; GDSC2 -2.016 0.1072 -2.0459 40.2909
NCI-H250 GDSC2 -2.0128 -0.2625 -2.0231 40.3159
SBC-5 GDSC2 -1.9795 0.5673 -2.052 49.7596
LCLC-97TM1 GDSC2 -1.9381 0.2717 -1.9774 49.2542
HCC827 GDSC2 -1.9157 0.1426 -1.9439 48.9748
HCC78 GDSC2 -1.8156 0.6107 -1.8833 47.8159
NCI-H1755 GDSC2 -1.6002 0.8991 -1.6923 45.2957
A-549 GDSC2 -1.5873 1.4494 -1.7795 45.3888
IST-SL1 GDSC1; GDSC2 -1.5754 0.0995 -1.5893 35.8222
COR-L23 GDSC2 -1.5168 1.2646 -1.6651 44.462
Lu-139 GDSC1; GDSC2 -1.5108 0.5284 -1.5521 35.3078
SHP-77 GDSC1; GDSC2 -1.5081 0.7967 -1.5796 35.4227
NCI-H358 GDSC2 -1.4942 1.1174 -1.6137 44.1115
NCI-H1781 GDSC2 -1.4548 1.0604 -1.5616 43.6004
Lu-135 GDSC2 -1.4527 0.5641 -1.4944 43.3419
LC-1/sq GDSC2 -1.428 1.0276 -1.5275 43.2539
NCI-H2461 GDSC2 -1.401 1.9866 -1.7079 43.5737
NCI-H2009 GDSC2 -1.3815 1.1841 -1.5039 42.777
NCI-H1355 GDSC1; GDSC2 -1.325 0.6965 -1.3733 33.4885
NCI-H2373 GDSC2 -1.2977 1.4246 -1.4596 41.9221
SW1271 GDSC2 -1.2706 1.2575 -1.3975 41.4633
NCI-H1693 GDSC2; CTRP2 -1.2343 1.2469 -1.2507 37.0926
EMC-BAC-1 GDSC2 -1.221 0.3427 -1.2363 32.3996
PaCa-3 GDSC2 -1.2204 1.2167 -1.3359 40.8105
RERF-LC-Sq1 GDSC2 -1.2148 1.038 -1.3003 40.6106
NCI-H1963 GDSC1; GDSC2 -1.1628 0.482 -1.1844 31.7363
NCI-H64 GDSC1; GDSC2 -1.1612 1.0954 -1.2516 32.0609
A-427 GDSC2 -1.1296 0.9145 -1.1918 31.7174
NCI-H2291 GDSC2 -1.1254 1.1352 -1.2196 31.8339
NCI-H2030 GDSC2 -1.0866 2.0745 -1.3891 32.4514
NCI-H1304 GDSC1 -1.0539 -0.1161 -1.1206 13.607
NCI-H2227 GDSC1; GDSC2 -1.053 1.2055 -1.1534 31.0322
NCI-H2810 GDSC2 -1.0382 0.7426 -1.0755 30.6768
COR-L303 GDSC2 -1.0327 0.2569 -1.0394 30.467
HOP-62 GDSC1; GDSC2 -1.0226 1.6497 -1.2101 31.1604
SK-LU-1 GDSC2 -0.9998 1.0077 -1.0659 37.8702
HOP-92 GDSC2 -0.9729 1.4693 -1.1164 37.9372
COR-L321 GDSC2 -0.9673 0.4618 -0.9808 29.845
KNS-62 GDSC2 -0.9594 0.7917 -0.9973 37.2142
SBC-1 GDSC1; GDSC2 -0.9581 0.6397 -0.9826 29.704
Calu-3 GDSC2 -0.9347 2.2308 -1.2686 38.3638
HCC15 GDSC2 -0.8762 1.8087 -1.0888 37.1105
HCC366 GDSC2 -0.8601 0.3739 -0.8669 28.7357
NCI-H2722 GDSC2 -0.85 1.6605 -1.0246 36.6015
NCI-H2869 GDSC2 -0.8277 1.5866 -0.9837 29.1701
NCI-H1876 GDSC1; GDSC2 -0.8269 1.7682 -1.025 29.2741
NCI-H2081 GDSC1; GDSC2; CTRP2 -0.8073 0.8711 -0.8091 34.199
LB647-SCLC GDSC1; GDSC2 -0.7996 1.7551 -0.9921 28.9744
NCI-H290 GDSC2 -0.7957 0.2417 -0.7982 28.0677
HCC33 GDSC1; GDSC2 -0.7883 0.2163 -0.7904 27.8935
NCI-H1155 GDSC1; GDSC2 -0.788 0.9657 -0.8351 28.118
NCI-H596 GDSC2 -0.7784 1.0329 -0.8332 35.0596
NCI-H748 GDSC1; GDSC2 -0.7783 0.5816 -0.7921 27.8526
NCI-H2087 GDSC2 -0.7731 2.4571 -1.1625 36.7404
NCI-H524 GDSC1; GDSC2 -0.6976 1.181 -0.7676 27.3317
NCI-H1734 GDSC2 -0.6656 0.9832 -0.7074 26.9621
NCI-H650 GDSC2 -0.641 1.0218 -0.6858 33.2886
COR-L32 GDSC2 -0.6394 0.7652 -0.6597 26.5892
LK-2 GDSC2 -0.6388 3.1626 -1.2638 36.2877
CPC-N GDSC1; GDSC2 -0.6308 1.5717 -0.7665 27.003
Lu-134-A GDSC1; GDSC2 -0.6294 1.1613 -0.6917 26.6105
NCI-H2347 GDSC2 -0.6271 2.8212 -1.1269 35.5805
NCI-H3255 GDSC2 -0.6239 2.4437 -0.996 28.2494
NCI-H1703 GDSC2; CTRP2 -0.6033 0.4862 -0.6034 32.8333
NCI-H146 GDSC2; CTRP2 -0.6003 0.7524 -0.6007 32.8145
IST-SL2 GDSC1; GDSC2 -0.5294 1.5553 -0.6529 25.9282
NCI-H2141 GDSC1; GDSC2; CTRP2 -0.5259 2.3096 -0.5849 32.5127
PC-14 GDSC2 -0.5083 0.7294 -0.5212 25.2361
NCI-H2804 GDSC2 -0.5018 1.7193 -0.6591 25.9197
Calu-6 GDSC1; GDSC2 -0.4941 1.641 -0.6329 25.6556
NCI-H2591 GDSC2 -0.4885 2.5476 -0.8829 33.4296
NCI-H513 GDSC2 -0.4829 3.0219 -1.0441 34.2332
NCI-H1048 GDSC2 -0.4782 1.1747 -0.5321 31.3145
NCI-H1299 GDSC1; GDSC2 -0.4618 1.4079 -0.5512 25.0753
EPLC-272H GDSC2 -0.4481 1.5433 -0.5623 31.3131
NCI-H82 GDSC1; GDSC2 -0.4362 0.114 -0.4363 24.3626
NCI-H1792 GDSC2 -0.4264 1.3974 -0.5112 30.8613
NCI-H460 GDSC2 -0.4224 1.5684 -0.5396 24.9139
NCI-H2122 GDSC2 -0.4063 2.3503 -0.7294 32.0471
DMS 114 GDSC1; GDSC2 -0.3936 1.6353 -0.5224 24.6003
LC-2/ad GDSC1; GDSC2 -0.3811 0.5619 -0.3844 23.8272
NCI-H526 GDSC1; GDSC2 -0.3659 1.4882 -0.4624 24.1545
NCI-H1869 GDSC1; GDSC2; CTRP2 -0.3196 2.2784 -0.3654 31.0947
NCI-H1581 GDSC1; GDSC2 -0.2974 1.4651 -0.384 23.418
NCI-H720 GDSC1; GDSC2 -0.2813 2.2718 -0.5689 24.3248
NCI-H522 GDSC2; CTRP2 -0.2783 1.0154 -0.2788 30.6684
NCI-H520 GDSC2; CTRP2 -0.2778 2.1347 -0.3106 30.7725
NCI-H810 GDSC2; CTRP2 -0.2655 1.077 -0.2662 30.5834
NCI-H1105 GDSC2; CTRP2 -0.2655 0.5229 -0.2655 30.581
NCI-H1694 GDSC1; GDSC2 -0.2638 0.9424 -0.2813 22.7261
NCI-H2369 GDSC2 -0.2521 1.8162 -0.4102 29.1547
Ms-1 GDSC1; GDSC2 -0.2352 1.5666 -0.3362 22.8722
NCI-H3122 GDSC2 -0.2339 3.088 -0.8023 31.3958
NCI-H1650 GDSC1; GDSC2 -0.2193 2.8205 -0.6869 24.678
SW1573 GDSC2 -0.2146 2.2624 -0.4932 29.4482
NCI-H196 GDSC2 -0.2084 1.7636 -0.3499 28.5068
NCI-H1648 GDSC1; GDSC2 -0.2062 2.0678 -0.4266 23.2171
RERF-LC-KJ GDSC2 -0.1987 1.7047 -0.3258 28.2933
NCI-H1341 GDSC2; CTRP2 -0.1911 0.4893 -0.1911 30.0854
NCI-H510A GDSC1; GDSC2 -0.1813 0.7207 -0.1853 21.8332
IA-LM GDSC2; CTRP2 -0.1404 1.7692 -0.1506 29.7812
NCI-H841 GDSC2; CTRP2 -0.1286 2.5129 -0.1865 29.8625
NCI-H661 GDSC2 -0.1245 2.151 -0.3615 28.0778
NCI-H2803 GDSC2 -0.1184 1.7896 -0.258 21.9861
NCI-H1436 GDSC1; GDSC2 -0.1165 0.6925 -0.1188 21.1767
NCI-H226 GDSC1; GDSC2 -0.1121 2.0593 -0.3215 22.2199
NCI-H1993 GDSC2 -0.0804 2.1576 -0.3154 27.5203
CAL-12T GDSC2 -0.0637 3.0683 -0.613 23.6737
NCI-H1092 GDSC1; GDSC2; CTRP2 -0.0498 2.5057 -0.1028 29.3214
NCI-H211 GDSC1; GDSC2 -0.0474 1.3383 -0.0946 20.7145
NCI-H1437 GDSC2 -0.0429 2.7968 -0.4885 22.9
NCI-H441 GDSC2 -0.0398 4.9864 -1.4095 33.2832
EKVX GDSC1; GDSC2 0.002 2.7793 -0.4338 22.3232
NCI-H1563 GDSC2 0.0164 2.4346 -0.2973 26.8369
NCI-H1688 GDSC2 0.0232 2.0808 -0.1799 26.0291
NCI-H345 GDSC1; GDSC2 0.0455 0.7961 0.0432 19.5565
NCI-H1666 GDSC1; GDSC2 0.0869 2.6883 -0.3093 21.2638
DV-90 CTRP2 0.0873 1.1424 0.0871 28.2299
NCI-H2196 GDSC1; GDSC2; CTRP2 0.0938 2.0797 0.0771 28.2417
NCI-H322M GDSC1; GDSC2 0.0971 2.5799 -0.2597 20.9446
DMS 273 GDSC2; CTRP2 0.103 1.8705 0.0945 28.1531
DMS 53 GDSC2 0.2168 2.5532 -0.1209 24.529
NCI-H740 GDSC2 0.2175 3.1828 -0.3599 21.0607
NCI-H2228 GDSC2 0.2451 3.8007 -0.5907 27.405
NCI-H2595 GDSC2 0.25 2.2723 0.0094 23.4643
SK-MES-1 GDSC2; CTRP2 0.3034 2.5964 0.26 26.9346
NCI-H1770 GDSC1; GDSC2 0.3717 1.8045 0.2723 16.7985
NCI-H1573 GDSC2 0.387 2.6553 0.0256 22.5916
NCI-H727 GDSC2 0.3983 2.7647 -0.0034 22.729
HCC4006 CTRP2 0.4182 2.2196 0.4043 26.0699
NCI-H1838 GDSC1; GDSC2 0.4289 2.7988 0.0163 17.9658
ChaGo-K-1 GDSC2; CTRP2 0.4556 2.1429 0.4457 25.8071
Lu-99A GDSC2 0.463 2.9462 -0.0052 22.3935
NCI-H1915 GDSC2; CTRP2 0.485 1.9773 0.4803 25.5939
DMS 79 GDSC1; GDSC2 0.5024 2.067 0.3468 15.7966
NCI-H835 GDSC2 0.5202 2.3316 0.2837 20.0772
NCI-H2029 GDSC2; CTRP2 0.5934 2.8333 0.5421 25.0285
NCI-H1568 GDSC2; CTRP2 0.596 2.2842 0.5841 24.8778
COR-L47 CTRP2 0.6794 3.1349 0.5967 24.5628
NCI-H128 GDSC1 0.6879 3.94 -1.4303 8.9679
NCI-H23 GDSC1; GDSC2; CTRP2 0.6926 2.1286 0.6875 24.2112
NCI-H1435 GDSC2 0.8653 2.3327 0.6571 15.5859
NCI-H2110 GDSC2; CTRP2 0.8727 4.4221 0.5299 24.1881
LK2 CTRP2 0.8741 2.1499 0.8711 22.9943
NCI-H1836 GDSC1; GDSC2 0.9113 3.9577 0.0127 16.0733
NCI-H838 GDSC2; CTRP2 0.9212 2.1361 0.9188 22.6784
NCI-H2023 GDSC2 0.9475 3.8141 0.1152 19.0952
NCI-H647 GDSC2; CTRP2 0.9642 2.6393 0.9457 22.4456
NCI-H2170 GDSC2; CTRP2 0.9893 2.1195 0.9877 22.2217
COR-L51 CTRP2 1.0002 2.3201 0.9955 22.1594
NCI-H2405 GDSC2 1.0131 3.7686 0.2013 18.1589
NCI-H2135 GDSC1; GDSC2 1.146 3.3701 0.5178 12.1596
Lu-65 GDSC1; GDSC2; CTRP2 1.1576 2.5755 1.1481 21.126
COR-L95 GDSC1; GDSC2; CTRP2 1.2122 2.2347 1.2111 20.7341
COLO 668 GDSC1; GDSC2; CTRP2 1.2174 2.3501 1.215 20.7037
RERF-LC-MS GDSC2; CTRP2 1.2579 3.6278 1.1388 20.8335
LC-1/sq-SF CTRP2 1.3079 2.1936 1.3074 20.0939
NCI-H1623 GDSC2; CTRP2 1.3563 4.1388 1.1335 20.5443
NCI-H2342 GDSC2; CTRP2 1.3687 3.5751 1.2679 20.0313
T3M-10 CTRP2 1.3918 4.1372 1.1727 20.2947
VMRC-LCD GDSC2; CTRP2 1.5193 2.9693 1.5007 18.7455
COR-L105 GDSC2; CTRP2 1.5822 2.4788 1.5812 18.2672
NCI-H2172 GDSC2 1.7021 3.1639 1.1544 6.2878
NCI-H1339 CTRP2 1.7334 2.5793 1.7325 17.2588
NCI-H1793 GDSC2 1.7616 5.1833 0.2055 14.9074
COR-L88 GDSC1; GDSC2; CTRP2 1.8217 3.8435 1.7075 17.0598
NCI-H187 GDSC1 1.8404 2.9951 -0.3721 0.195
BEN GDSC2 1.8929 3.8534 0.9826 6.7599
RERF-LC-Ad2 CTRP2 1.9983 4.1265 1.8367 16.0509
NCI-H2444 GDSC2 2.0304 3.8069 1.1217 5.4729
NCI-H1944 GDSC2; CTRP2 2.2336 5.4886 1.6444 16.0776
NCI-H322 CTRP2 2.2936 3.2931 2.2832 13.5563
UMC-11 GDSC2 2.3769 5.7637 0.4223 11.0594
NCI-H1395 CTRP2 2.6907 5.6195 2.0741 13.1647
LUDLU-1 CTRP2 2.8576 5.0592 2.4758 11.1548
Lu-165 GDSC1; GDSC2 2.9085 10.2357 -1.3874 17.6385
NCI-H2066 GDSC2 3.0255 5.5564 0.9865 4.947
Hs 888.Lu CTRP2 1.6755 3.9152 1.5338 18.1306
⏷ Show the Full List of 200 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 -0.6009 1.2952 -0.6818 26.4213
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 0.9097 2.9902 0.8595 22.9164
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 1.0049 1.4585 1.0049 22.1123
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A2780 GDSC2 -2.9742 -1.4374 -2.9754 62.07
OC 314 GDSC2 -2.4968 -1.1041 -2.4978 56.1847
Caov-4 GDSC2 -2.4942 -0.2397 -2.5196 55.9235
OVISE GDSC2 -2.4765 -1.1197 -2.4774 55.9364
JHOS-4 GDSC2 -2.465 -0.8402 -2.4685 44.8197
Caov-3 GDSC2 -2.3918 -0.2425 -2.4135 44.1487
TYK-nu GDSC2 -2.2477 0.3909 -2.3156 52.8806
ES-2 GDSC1; GDSC2 -1.9849 -0.5503 -1.9878 39.863
OVCAR-3 GDSC2 -1.9809 0.0767 -2.0072 49.7674
OVCAR-4 GDSC1; GDSC2 -1.8781 -0.0651 -1.8929 38.8503
DOV13 GDSC2 -1.3332 0.5383 -1.3666 41.8312
FU-OV-1 GDSC2 -1.2551 1.8965 -1.5246 41.8078
IGROV-1 GDSC2 -1.214 0.7247 -1.259 40.4112
OVTOKO GDSC2 -1.1411 1.4119 -1.2871 39.9848
OVCAR-5 GDSC2 -1.1374 1.2154 -1.2461 39.7722
RMG-I GDSC2 -1.1266 3.1721 -1.7912 41.6412
OVK18 GDSC2 -1.0698 0.1385 -1.0739 30.8262
OVCAR-8 GDSC2 -1.0582 0.3367 -1.0684 38.2878
SK-OV-3 GDSC2 -1.0182 2.1078 -1.3239 39.2127
Kuramochi GDSC1; GDSC2 -0.4239 2.0486 -0.6587 25.4611
TOV-21G GDSC2; CTRP2 -0.405 0.2996 -0.405 31.5114
COV644 CTRP2 -0.3334 0.5098 -0.3334 31.0336
OV7 CTRP2 -0.1693 0.7912 -0.1694 29.9402
JHOM-1 CTRP2 -0.0755 0.7358 -0.0755 29.3148
OAW28 GDSC2; CTRP2 -0.0026 2.7189 -0.0759 29.0751
OV-90 GDSC2; CTRP2 0.2215 1.9275 0.2136 27.3611
TOV-112D GDSC2; CTRP2 0.9429 3.061 0.8867 22.7157
JHOS-2 GDSC2; CTRP2 1.0262 3.2985 0.9441 22.2495
OV56 GDSC2; CTRP2 1.1337 2.1676 1.1327 21.257
COV362 CTRP2 1.3509 3.9588 1.171 20.4281
OVKATE GDSC2 1.5104 6.201 -0.5212 20.9513
OAW42 GDSC2; CTRP2 1.5608 2.4597 1.5598 18.4098
EFO-27 GDSC2; CTRP2 2.1216 4.3647 1.9089 15.4137
EFO-21 GDSC2; CTRP2 2.4258 3.7515 2.3759 12.8099
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H2052 GDSC2 -1.9533 1.2447 -2.134 49.486
NCI-H2452 GDSC2 -1.5448 1.2537 -1.6934 44.7912
IST-Mes1 GDSC1; GDSC2; CTRP2 -0.384 1.8743 -0.4049 31.4407
MSTO-211H GDSC1; GDSC2 -0.335 2.1062 -0.578 24.6201
NCI-H28 GDSC2 0.2578 4.5565 -0.9147 29.2092
MPP 89 GDSC1; GDSC2; CTRP2 1.676 2.2744 1.676 17.6384
JL-1 CTRP2 2.5661 4.2908 2.4142 12.2357
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
22Rv1 GDSC2 -2.0878 1.2427 -2.2795 50.9513
PC-3 GDSC2 -0.6869 1.8124 -0.8832 34.7336
VCaP GDSC1; GDSC2; CTRP2 -0.562 2.5313 -0.6471 32.8387
NCI-H660 GDSC2 -0.2593 1.4157 -0.3342 23.0571
LNCaP clone FGC GDSC1; GDSC2; CTRP2 0.5581 3.178 0.4606 25.4217
DU145 GDSC2; CTRP2 1.2065 3.627 1.0834 21.1902
PaCa-3 CTRP2 1.713 2.2847 1.713 17.392
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; GDSC2; CTRP2 0.0624 1.9181 0.0516 28.4313
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 -1.5644 -0.0236 -1.573 35.6866
Cancer Drug Sensitivity Data Curated from 25 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 633.T GDSC2 -2.2786 -0.5217 -2.2861 53.435
KYM-1 GDSC2 -2.2709 -0.8722 -2.2725 53.3736
SW872 GDSC1; GDSC2 -2.1902 -1.0767 -2.1905 41.9033
SW982 GDSC2 -2.0723 -0.1761 -2.0876 50.8868
Rh41 GDSC2 -2.0643 -0.1634 -2.0799 50.788
A-204 GDSC2 -1.6324 0.9646 -1.737 45.7109
VA-ES-BJ GDSC1; GDSC2 -1.4743 0.9694 -1.5681 35.1903
MFH-ino GDSC1; GDSC2 -1.4592 0.451 -1.4911 34.748
G-402 GDSC2; CTRP2 -1.3164 1.1802 -1.3322 37.6379
SW684 GDSC1; GDSC2 -1.0973 0.4624 -1.1152 31.0628
STS-0421 GDSC2 -0.8713 0.8097 -0.9064 28.9914
RKN GDSC2 -0.7804 1.1841 -0.8568 35.2105
EW-8 GDSC1; GDSC2 -0.5786 0.9938 -0.6166 25.9781
Rh18 GDSC2 -0.5482 0.9867 -0.5837 32.0741
MES-SA GDSC2; CTRP2 -0.3951 0.0388 -0.3951 31.4453
GCT GDSC2 -0.2634 2.1708 -0.5188 29.9032
TE 441.T GDSC1; GDSC2; CTRP2 -0.1638 0.6884 -0.1638 29.9032
TE 617.T CTRP2 -0.1153 0.8062 -0.1153 29.5798
Rh30 GDSC2 -0.0228 1.9654 -0.1981 26.4183
HT-1080 GDSC2; CTRP2 0.2271 1.6974 0.2241 27.3074
Hs 729.T CTRP2 0.3749 1.6986 0.3731 26.3181
G-401 GDSC2; CTRP2 0.5376 1.858 0.5354 25.235
RD GDSC2; CTRP2 0.8712 2.8861 0.8296 23.1438
SK-UT-1 GDSC1; GDSC2; CTRP2 0.9104 2.4684 0.899 22.7804
SK-LMS-1 GDSC1; GDSC2; CTRP2 1.0526 2.1288 1.0513 21.7985
⏷ Show the Full List of 25 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 GDSC2 -3.5725 -1.5723 -3.5765 68.917
MKN1 GDSC2 -2.8214 -1.2455 -2.8231 60.1725
TGBC11TKB GDSC2 -2.4641 -1.0512 -2.4654 55.7767
AGS GDSC2 -2.3059 -0.399 -2.318 53.747
HGC-27 GDSC2 -2.2205 -0.6219 -2.2249 52.733
MKN45 GDSC2 -2.0199 0.551 -2.0929 50.2327
23132/87 GDSC2 -2.0105 0.1705 -2.0448 50.1269
MKN28 GDSC2 -1.9659 0.6811 -2.0523 49.6031
NUGC-3 GDSC2 -1.5582 0.7951 -1.6328 44.7414
RERF-GC-1B GDSC2 -1.2067 1.1985 -1.3178 40.625
SNU-16 GDSC1; GDSC2; CTRP2 -1.0727 0.2 -1.0728 35.9626
NCI-N87 GDSC1; GDSC2 -1.0217 2.7829 -1.5404 32.6991
SK-GT-2 GDSC2 -0.9792 1.0655 -1.052 37.6511
SNU-5 GDSC1; GDSC2 -0.7455 1.2181 -0.8247 27.8568
GCIY GDSC1; GDSC2 -0.675 1.7159 -0.8469 27.6304
RF-48 GDSC1; GDSC2 -0.6681 0.8709 -0.6985 26.8343
OCUM-1 GDSC2 -0.6615 2.5449 -1.0698 35.534
HSC-39 GDSC1; GDSC2 -0.5036 0.4399 -0.5061 25.0488
NCC-StC-K140 CTRP2 -0.4562 2.7689 -0.5653 32.2134
Fu97 GDSC2 -0.354 3.0483 -0.9157 32.7541
ECC12 GDSC1; GDSC2 -0.3264 1.5117 -0.4241 23.766
MKN7 GDSC2; CTRP2 -0.2842 2.9256 -0.4039 31.1051
TMK-1 GDSC2 -0.234 1.8735 -0.4047 23.31
Hs 746.T GDSC2; CTRP2 -0.0498 0.9334 -0.0499 29.1435
HuG1-N CTRP2 -0.0039 1.7862 -0.0119 28.8641
SCH GDSC1; GDSC2 0.0718 1.1729 0.0509 19.3878
NUGC-4 GDSC2 0.2387 3.1268 -0.3148 25.6953
SNU-1 GDSC1; GDSC2; CTRP2 0.5104 2.4955 0.4842 25.4966
SH-10-TC CTRP2 0.7643 2.1086 0.7606 23.7285
KATO III GDSC2; CTRP2 1.0352 3.3072 0.9525 22.1914
LMSU CTRP2 1.0656 2.1263 1.0644 21.7117
IM95 GDSC2; CTRP2 1.3599 2.6069 1.3538 19.7659
MKN74 CTRP2 1.805 4.7099 1.4601 18.0023
SNG-M GDSC2 -2.4199 -1.0556 -2.4209 55.2311
SNU-685 CTRP2 0.8119 2.179 0.8075 23.4139
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TT GDSC2 -2.9667 -1.5659 -2.9672 62.0186
8305C GDSC2 -2.4903 0.4774 -2.5842 55.5144
8505C GDSC2 -2.4259 0.0582 -2.4701 55.0159
HTC-C3 GDSC2 -2.3494 -0.4194 -2.3617 54.2742
BHT-101 GDSC2 -2.2343 0.1848 -2.2803 52.7763
ASH-3 GDSC2 -1.9226 0.4559 -1.9789 49.0794
IHH-4 GDSC2 -1.84 0.0114 -1.8575 48.0344
B-CPAP GDSC2 -1.4458 0.5094 -1.4821 43.2349
CAL-62 GDSC2 -1.3284 0.8579 -1.3962 41.923
WRO GDSC2 -0.9478 2.2146 -1.2781 38.5003
KMH-2 GDSC2 -0.6973 0.1233 -0.6979 27.0708
K5 GDSC1; GDSC2 -0.5243 1.1915 -0.5836 25.5447
ML-1 [Human leukemia] GDSC2 -0.4258 1.3941 -0.51 24.7753
CGTH-W-1 GDSC1; GDSC2 -0.3132 1.2203 -0.3622 23.3808
FTC-238 CTRP2 0.2511 1.1966 0.251 27.1376
SW579 CTRP2 0.2871 1.323 0.2869 26.8978
FTC-133 GDSC2; CTRP2 1.5846 2.8486 1.5748 18.2804
TT2609-C02 GDSC2; CTRP2 2.2355 3.6773 2.183 14.0871
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Ca9-22 GDSC2 -3.1535 -1.2549 -3.1579 64.0531
HO-1-u-1 GDSC2 -3.149 -1.7142 -3.1495 64.2621
LB771-HNC GDSC1; GDSC2 -3.0446 0.1407 -3.1313 50.4185
NCI-H3118 GDSC2 -2.5109 0.0236 -2.5562 55.9883
OSC-19 GDSC2 -2.4201 -0.4553 -2.4328 44.4016
JHU-022 GDSC2 -2.2144 0.106 -2.2528 52.5608
HO-1-N-1 GDSC2 -2.0913 -0.4519 -2.0975 51.131
SAS GDSC2 -1.9877 0.079 -2.0144 49.85
SKN-3 GDSC2 -1.9431 0.1441 -1.9725 49.3094
BB30-HNC GDSC1; GDSC2 -1.9326 -0.7744 -1.9332 39.3286
OSC-20 GDSC2 -1.9251 0.3437 -1.9702 49.102
BB49-HNC GDSC1; GDSC2 -1.7109 0.8281 -1.8005 37.5161
JHU-011 GDSC2 -1.6393 0.5116 -1.6858 36.7416
PCI-30 GDSC2 -1.6057 0.7284 -1.6747 45.299
BICR 10 GDSC2 -1.6033 1.3053 -1.7668 45.5078
KOSC-2 GDSC2 -1.5735 0.3838 -1.6052 36.0137
Detroit 562 GDSC2 -1.4598 1.2197 -1.5949 43.751
SCC-4 GDSC2 -1.4138 0.8711 -1.4891 42.9945
BICR 78 GDSC2 -1.386 0.6954 -1.4377 42.5617
CAL-33 GDSC2 -1.3592 0.6721 -1.4068 42.2158
SCC-15 GDSC1; GDSC2 -1.2012 0.9672 -1.2753 32.3792
PCI-04B GDSC2 -1.0074 0.8987 -1.0599 30.4438
KON GDSC2 -0.9777 0.0569 -0.9794 29.8897
PCI-15A GDSC2 -0.8987 0.4735 -0.9106 29.1486
BHY GDSC2 -0.8459 0.295 -0.8502 28.5809
DOK GDSC2 -0.8078 1.4381 -0.9311 35.8123
UPCI-SCC-090 GDSC2 -0.8055 1.363 -0.9143 35.7033
JHU-029 GDSC2 -0.7334 1.2023 -0.8091 27.8155
HSC-3 GDSC2 -0.5994 2.0186 -0.8419 33.926
PCI-06A GDSC2 -0.3747 1.2587 -0.4333 24.1299
SCC-25 GDSC2 -0.3704 1.7184 -0.5158 24.5418
CAL-27 GDSC2; CTRP2 -0.3338 2.6007 -0.4132 31.3013
HSC-4 GDSC2 -0.1701 1.6714 -0.2874 27.8751
SAT [Human HNSCC] GDSC2 -0.0194 2.1981 -0.261 26.809
PE/CA-PJ49 CTRP2 0.2158 1.2667 0.2157 27.373
HSC-2 GDSC2; CTRP2 0.2257 1.3586 0.2254 27.3077
FaDu GDSC2; CTRP2 1.0136 2.1537 1.0119 22.0599
SCC-9 GDSC2; CTRP2 1.216 2.4724 1.211 20.7217
PE/CA-PJ15 GDSC2; CTRP2 1.3207 2.397 1.3186 20.0143
BICR 6 CTRP2 1.4154 2.4954 1.4128 19.3845
BICR 31 GDSC2; CTRP2 1.6672 3.9986 1.5062 18.2538
PE/CA-PJ41 (clone D2) CTRP2 1.6833 3.5668 1.6078 17.8473
BICR 22 GDSC2; CTRP2 1.7235 2.305 1.7234 17.3222
PE/CA-PJ34 (clone C12) CTRP2 1.7525 2.389 1.7524 17.1287
BICR 18 CTRP2 1.9709 2.6993 1.9704 15.6743
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RT-112 GDSC2 -3.0068 -1.165 -3.0111 62.3211
BFTC-905 GDSC2 -2.986 -1.5712 -2.9865 62.2539
SW1710 GDSC2 -2.6446 -1.1395 -2.6462 58.0041
639V GDSC2 -1.9963 -0.1758 -2.0095 49.9546
RT-4 GDSC2 -1.8456 0.068 -1.8664 48.1093
CAL-29 GDSC2 -1.727 0.4517 -1.7721 46.7072
5637 GDSC2 -1.7145 0.248 -1.742 46.5128
UM-UC-3 GDSC2 -1.4643 0.3293 -1.4874 43.4094
KU-19-19 GDSC2 -1.2052 1.1856 -1.314 40.5971
SW780 GDSC2 -0.6264 1.5387 -0.7548 33.6063
TCCSUP GDSC2 -0.4356 1.4651 -0.5335 31.0567
HT-1376 GDSC2 -0.3843 2.4103 -0.7246 31.8817
HT-1197 GDSC2; CTRP2 -0.3572 2.7812 -0.4613 31.5387
647V GDSC2; CTRP2 0.1706 1.3975 0.17 27.6761
SCaBER CTRP2 0.3302 1.3019 0.3301 26.6106
UM-UC-1 CTRP2 0.342 1.7299 0.3397 26.5392
J82 GDSC2; CTRP2 0.5352 2.4641 0.512 25.3211
T24 GDSC2; CTRP2 0.9379 2.3921 0.93 22.5853
BC-3C CTRP2 1.2819 2.3753 1.2796 20.2734
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
DSH1 GDSC1; GDSC2 -4.4251 -2.5742 -4.426 64.1354
NT2-D1 GDSC1; GDSC2 -3.6516 -2.6481 -3.6516 56.5154
DoTc2 4510 GDSC2 -3.0958 -1.5182 -3.097 63.5493
NEC8 GDSC1; GDSC2 -3.0934 -1.2898 -3.0967 50.9299
Ca Ski GDSC2 -2.6455 -0.7847 -2.6525 57.9132
PA-1 GDSC2 -2.5874 -0.8795 -2.5916 57.2494
C-4-I GDSC2 -2.3899 -0.8948 -2.3921 54.8453
PWR-1E GDSC2 -2.1772 -0.3242 -2.1891 52.1771
HEC-1 GDSC2 -2.1745 0.0157 -2.2043 52.103
LB831-BLC GDSC1; GDSC2 -2.1574 -0.921 -2.1581 41.5773
PEO1 GDSC2 -2.1204 0.457 -2.1884 51.4087
NCC-IT GDSC1; GDSC2 -2.1078 -0.8349 -2.1088 41.083
OVCA433 GDSC2 -2.0909 -0.1299 -2.1089 41.1309
C-33 A GDSC2 -2.0697 0.1236 -2.103 50.8399
SKN GDSC2 -1.8787 0.1742 -1.9076 48.5251
OVMIU GDSC2 -1.7377 1.495 -1.953 47.1283
BPH-1 GDSC2 -1.7161 1.0985 -1.8497 46.7528
SiSo GDSC2 -1.2984 1.0579 -1.3931 41.6683
CAL-39 GDSC2 -1.2952 0.7764 -1.3507 41.4624
ME-180 GDSC2 -1.208 1.8075 -1.4503 41.1664
KGN GDSC1; GDSC2 -1.0835 1.3695 -1.2163 31.4959
JHOS-3 GDSC2 -0.7409 0.9346 -0.7817 27.7122
JAR GDSC1; GDSC2 -0.7252 1.2055 -0.8009 27.6368
JEG-3 GDSC2 -0.6782 1.6422 -0.8334 27.6724
ACC-OV7 GDSC2 -0.6535 1.6621 -0.8111 27.4379
SiHa GDSC2 -0.5559 1.5878 -0.6885 32.7598
HEY GDSC2 -0.5078 1.7541 -0.6738 32.3647
TC-YIK GDSC1; GDSC2 -0.4694 2.0348 -0.7045 25.9149
UWB1.289 GDSC2 -0.4322 1.7633 -0.5937 25.2452
OV17R GDSC2 -0.3088 0.9949 -0.3325 23.2892
SKG-IIIa GDSC2 -0.222 1.8066 -0.375 28.7487
SW954 GDSC1; GDSC2 -0.1478 0.9082 -0.1587 21.5329
MS751 GDSC2 0.0017 2.0327 -0.1898 26.2199
HT-3 GDSC2 0.0169 2.3808 -0.2791 26.7154
SW756 GDSC2 0.2591 3.3262 -0.3747 25.9724
OVCA420 GDSC2 0.3535 3.1606 -0.2075 24.359
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 0.5937 2.1768 0.4136 15.0194
SW962 GDSC1; GDSC2 0.6415 2.1565 0.4719 14.4852
HeLa GDSC2; CTRP2 1.0889 2.5503 1.0786 21.5867
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

1 Increased ABCB1 expression in TP-110-resistant RPMI-8226 cells. Biosci Biotechnol Biochem. 2010;74(9):1913-9.
2 Proteasome inhibition creates a chromatin landscape favorable to RNA Pol II processivity. J Biol Chem. 2020 Jan 31;295(5):1271-1287. doi: 10.1074/jbc.RA119.011174. Epub 2019 Dec 5.