Details of the Drug

General Information of Drug (ID: DML8S0W)

Drug Name
MEDI6570
Indication
Disease Entry ICD 11 Status REF
Cardiovascular disease BA00-BE2Z Phase 2 [1]
Coronary heart disease BA80.Z Phase 2 [1]
Drug Type
Antibody
Cross-matching ID
TTD ID
DFG87U
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Lectin-like oxidized LDL receptor (OLR1) TTKSND3 OLR1_HUMAN Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Cardiovascular disease
ICD Disease Classification BA00-BE2Z
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Lectin-like oxidized LDL receptor (OLR1) DTT OLR1 3.35E-01 -0.08 -0.35
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 ClinicalTrials.gov (NCT04610892) A Phase IIB, Randomized, Double Blinded, Placebo Controlled, Parallel Group Study to Evaluate the Efficacy and Safety of MEDI6570 in Participants With a Prior Myocardial Infarction and Persistent Inflammation. U.S.National Institutes of Health.
2 Clinical pipeline report, company report or official report of AstraZeneca