Details of the Drug

General Information of Drug (ID: DMLN280)

Drug Name
RQ-00000010
Synonyms
CJ-033466; PF-01354082; RQ-10; 5-HT 4 receptor partial agonist (GERD), RaQualia; 5-HT4 receptor partial agonist (gastric motility disorder), Pfizer; 5-hydroxytryptamine 4 receptor partial agonist (gastric motility disorder), Pfizer; 5-hydroxytryptamine 4 receptor partial agonist (gastroesophageal reflux), RaQualia
Indication
Disease Entry ICD 11 Status REF
Gastric motility disorder DA21 Investigative [1]
Structure 3D Structure is Not Available
3D MOL 2D MOL
Cross-matching ID
TTD ID
D0H1UY

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
5-HT 4 receptor (HTR4) TT07C3Y 5HT4R_HUMAN Agonist [1]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Gastric motility disorder
ICD Disease Classification DA21
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
5-HT 4 receptor (HTR4) DTT HTR4 6.16E-01 -0.03 -0.24
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

References

1 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 9).