Details of the Drug

General Information of Drug (ID: DMLVHAJ)

Drug Name
PX-12
Synonyms PX12, PX 12, IV-2
Indication
Disease Entry ICD 11 Status REF
Pancreatic cancer 2C10 Phase 2 [1]
Solid tumour/cancer 2A00-2F9Z Phase 2 [2]
Coronavirus Disease 2019 (COVID-19) 1D6Y Investigative [3]
Therapeutic Class
Anticancer Agents
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 188.3
Logarithm of the Partition Coefficient (xlogp) 2.3
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 3
Chemical Identifiers
Formula
C7H12N2S2
IUPAC Name
2-(butan-2-yldisulfanyl)-1H-imidazole
Canonical SMILES
CCC(C)SSC1=NC=CN1
InChI
InChI=1S/C7H12N2S2/c1-3-6(2)10-11-7-8-4-5-9-7/h4-6H,3H2,1-2H3,(H,8,9)
InChIKey
BPBPYQWMFCTCNG-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
219104
ChEBI ID
CHEBI:94291
CAS Number
141400-58-0
UNII
8PQ9CZ8BTJ
DrugBank ID
DB05448
TTD ID
D04JTD
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Thioredoxin (TXN) TTZJ5U9 THIO_HUMAN Inhibitor [4]
COVID-19 papain-like proteinase (PL-PRO) TTNHMO8 R1AB_SARS2 (819-2763) Inhibitor [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 141 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 2.9835 4.3458 2.9802 24.3733
JK1 CTRP2 3.3027 5.5155 3.2322 22.4764
JM1 CTRP2 2.171 2.7807 2.171 29.7702
NOMO-1 CTRP1 -1.3742 2.9684 -1.4414 87.2595
NU-DUL-1 CTRP2; CTRP1 -0.4949 0.4807 -0.4949 47.5132
PL21 CTRP2; CTRP1 -0.4512 0.7798 -0.4512 47.2224
GDM-1 CTRP2; CTRP1 0.1654 2.0087 0.1647 43.1208
SU-DHL-5 CTRP1 0.6723 1.5308 0.6723 84.9204
OCI-AML-3 CTRP2; CTRP1 1.0205 2.8177 1.0188 37.4328
WSU-DLCL2 CTRP2; CTRP1 1.0308 2.9486 1.028 37.3682
MOLT-13 CTRP2 1.3724 2.7826 1.3721 35.0864
NALM-6 CTRP2 1.427 2.3246 1.427 34.722
RCH-ACV CTRP2 1.4486 2.5732 1.4485 34.5784
SUP-T11 CTRP2 1.5548 3.0604 1.554 33.8742
P31/FUJ CTRP2 1.5626 3.1116 1.5616 33.8226
PF-382 CTRP2 1.5975 3.451 1.5932 33.6014
SEM CTRP2 1.6147 2.5007 1.6147 33.4728
NCI-H929 CTRP2 1.6596 2.9103 1.6594 33.1746
HuT 78 CTRP2 1.672 4.7784 1.5904 33.3592
ALL-SIL CTRP2 1.7557 3.1127 1.7553 32.5355
THP-1 CTRP2; CTRP1 1.7654 3.6875 1.7588 32.4918
MV4-11 CTRP2 1.8213 4.1383 1.7997 32.1695
Peer CTRP2 1.8634 3.182 1.863 31.8189
KMS-11 CTRP2 1.8998 3.563 1.8969 31.5846
ST486 CTRP2 1.9214 2.7192 1.9214 31.4316
NCO2 CTRP2 1.9519 3.762 1.9464 31.2466
MOLM-13 CTRP2 2.0118 3.0958 2.0117 30.8301
SKM-1 CTRP2; CTRP1 2.2007 4.0576 2.192 29.6015
KO52 CTRP2 2.2232 3.7104 2.2213 29.429
OPM-2 CTRP2 2.2345 2.8727 2.2345 29.3471
MHH-CALL-4 CTRP2 2.2484 3.8125 2.2454 29.2649
GA-10 CTRP2 2.2681 2.8428 2.2681 29.1236
KHM-1B CTRP2 2.2794 2.983 2.2794 29.0487
MHH-CALL-3 CTRP2 2.3178 4.9256 2.2574 28.9955
RPMI-8402 CTRP2 2.3456 3.5624 2.3452 28.6093
Pfeiffer CTRP2 2.3645 3.197 2.3644 28.4825
MOLM-6 CTRP2 2.3759 3.506 2.3756 28.4074
Daudi CTRP2 2.381 3.2562 2.381 28.3724
KMS-26 CTRP2 2.4057 3.2181 2.4057 28.2082
U-937 CTRP2; CTRP1 2.4403 4.0268 2.436 27.9919
EJM CTRP2; CTRP1 2.455 4.2984 2.4437 27.9173
Kasumi-2 CTRP2 2.4569 3.3499 2.4569 27.867
EM-2 CTRP2 2.4653 4.0785 2.4604 27.8275
SUP-T1 CTRP2 2.4834 3.9678 2.4805 27.7004
SK-MM-2 CTRP2 2.5532 5.0321 2.4947 27.4228
LP-1 CTRP2 2.5586 3.7088 2.5582 27.1917
SU-DHL-8 CTRP2 2.5645 4.4686 2.549 27.2029
SU-DHL-4 CTRP2; CTRP1 2.5826 4.7742 2.5491 27.1428
ME1 CTRP2 2.6017 4.2436 2.5951 26.9254
M-07e CTRP2 2.6074 3.9258 2.606 26.8703
KE-37 CTRP2 2.6611 3.5447 2.6611 26.5081
NU-DHL-1 CTRP2 2.6932 3.6673 2.693 26.2951
Kasumi-1 CTRP2 2.6986 3.6129 2.6985 26.2587
Hs 611.T CTRP2 2.7636 3.665 2.7635 25.8261
Reh CTRP2 2.8107 3.6583 2.8107 25.5123
EoL-1 CTRP2 2.8113 3.7683 2.8111 25.5092
Mino CTRP2 2.8256 3.4176 2.8256 25.413
P12-Ichikawa CTRP2 2.9082 3.7786 2.9081 24.8638
NB4 CTRP2 2.9389 4.6302 2.9265 24.7006
RS4;11 CTRP2 2.9856 4.0165 2.9852 24.3495
MOTN-1 CTRP2 2.9918 4.2567 2.9898 24.3135
TALL-1 [Human adult T-ALL] CTRP2 3.0034 4.5547 2.9953 24.2568
MM1.S CTRP2 3.0162 4.1901 3.015 24.1486
RPMI-8226 CTRP2; CTRP1 3.0442 4.6095 3.0352 23.9882
JeKo-1 CTRP2 3.0511 3.5036 3.0511 23.9122
KMS-12-BM CTRP2 3.069 3.7775 3.069 23.7933
KMS-20 CTRP2 3.0707 3.5926 3.0707 23.782
OCI-Ly19 CTRP2 3.0728 4.5736 3.0655 23.7921
HL-60 CTRP2 3.0746 3.6528 3.0746 23.7559
AML-193 CTRP2 3.0847 4.8886 3.0635 23.7596
DND-41 CTRP2 3.0901 4.4424 3.0863 23.6655
MOLT-16 CTRP2 3.1026 4.1139 3.1022 23.5711
MOLM-16 CTRP2; CTRP1 3.1028 4.544 3.0969 23.588
SUP-B15 CTRP2 3.1189 4.0124 3.1188 23.4616
OCI-Ly3 CTRP2 3.119 3.719 3.119 23.4607
SET-2 CTRP2 3.132 4.9985 3.1052 23.4638
Karpas-422 CTRP2 3.1517 3.5951 3.1517 23.243
MOLP-8 CTRP2 3.1588 3.6911 3.1588 23.1956
Ku812 CTRP2 3.177 5.1399 3.1409 23.1958
SIG-M5 CTRP2 3.1796 3.5317 3.1796 23.0572
DB CTRP2 3.1928 4.5866 3.1874 22.9872
KMS-21-BM CTRP2 3.1966 4.8859 3.1794 23.0017
A4/Fukuda CTRP2 3.2074 4.1053 3.2073 22.8724
JJN-3 CTRP2 3.2637 3.9434 3.2637 22.4977
SUP-HD1 CTRP2 3.2795 5.0641 3.2541 22.4774
P3HR-1 CTRP2 3.365 4.332 3.3645 21.8245
CML-T1 CTRP2 3.3928 4.6666 3.3885 21.6525
BV-173 CTRP2 3.4301 4.3428 3.4297 21.3914
Ci-1 CTRP2 3.4324 4.9992 3.4168 21.4268
HPB-ALL CTRP2 3.4359 4.2151 3.4359 21.3513
OCI-AML-2 CTRP2 3.5085 4.402 3.5082 20.869
L-1236 CTRP2 3.7403 5.3087 3.7162 19.4061
Mono-Mac-1 CTRP2 3.7502 6.4537 3.5357 20.004
DEL CTRP2 3.7648 4.9603 3.7594 19.1802
Granta-519 CTRP2 3.774 5.9373 3.6726 19.4471
KMS-18 CTRP2 3.8534 4.8902 3.8509 18.5808
SU-DHL-1 CTRP2 3.8776 4.6287 3.8774 18.4121
L-428 CTRP2 3.9043 5.4108 3.8795 18.3171
Jurkat CTRP2 3.9383 5.031 3.934 18.0216
L-363 CTRP2 3.9559 4.6237 3.9558 17.8908
KMS-34 CTRP2 3.9761 4.5648 3.976 17.7561
F-36P CTRP2 4.0291 5.5933 3.9938 17.5219
Ki-JK CTRP2 4.037 5.1658 4.0306 17.3721
Ri-1 CTRP2 4.0687 5.9862 3.9818 17.4358
REC-1 CTRP2 4.0704 6.5282 3.8661 17.8388
HT CTRP2 4.0715 4.7465 4.0714 17.1212
KCL-22 CTRP2 4.0861 5.2784 4.0764 17.0561
KM-H2 CTRP2 4.0879 5.1409 4.0833 17.0268
LAMA-84 CTRP2 4.1183 5.4817 4.0974 16.8794
CMK CTRP2 4.223 6.189 4.1107 16.498
MJ CTRP2 4.2298 6.8242 3.958 17.0236
Karpas-299 CTRP2 4.2359 5.007 4.2352 16.0288
MC116 CTRP2 4.2462 4.8409 4.2461 15.9584
EB1 CTRP2 4.3246 5.9848 4.2575 15.6645
HEL CTRP2 4.3279 5.146 4.3264 15.4193
U266B1 CTRP2 4.3322 5.3035 4.3275 15.4017
SU-DHL-10 CTRP2 4.3353 4.8149 4.3353 15.3652
AMO1 CTRP2 4.3725 5.472 4.3619 15.1529
KE-97 CTRP2 4.392 5.2832 4.3889 14.998
EHEB CTRP2 4.4468 5.7546 4.4178 14.7209
JURL-MK1 CTRP2 4.4614 5.586 4.4472 14.5736
KYO-1 CTRP2 4.5452 5.6468 4.5302 14.0184
Raji CTRP2 4.6006 6.0587 4.5422 13.7982
KMM-1 CTRP2 4.6539 6.9967 4.3665 14.2654
Karpas-620 CTRP2 4.6638 5.7028 4.6497 13.226
OCI-M1 CTRP2 4.779 7.1725 4.4433 13.615
MOLP-2 CTRP2 4.8498 6.1451 4.7961 12.1236
SR CTRP2 4.8875 6.2159 4.8247 11.9045
JVM-3 CTRP2 4.9293 6.2203 4.869 11.6176
L-540 CTRP2 4.9746 5.8578 4.9621 11.152
HuNS1 CTRP2 4.9789 6.7203 4.8054 11.6907
KMS-27 CTRP2 5.0404 5.565 5.0398 10.6743
HDLM-2 CTRP2 5.0649 6.3619 4.9886 10.7712
K-562 CTRP2 5.1147 6.8224 4.9231 10.8546
RL CTRP2 5.1632 7.0539 4.8999 10.7977
TF-1 CTRP2 5.2482 7.9588 4.634 11.5845
HEL 92.1.7 CTRP2 5.2831 6.7011 5.1428 9.5489
OCI-AML-5 CTRP2 5.3324 5.8061 5.3314 8.7322
RPMI-6666 CTRP2 5.3337 6.9794 5.1101 9.5195
BL-70 CTRP2 5.3472 6.6094 5.238 9.0108
HD-MY-Z CTRP2 5.6912 6.5829 5.6202 6.5874
⏷ Show the Full List of 141 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 4.6588 5.8473 4.6319 13.3024
TE15 CTRP2 6.4231 7.3323 6.102 2.7403
OE33 CTRP2 2.9905 8.5746 2.0027 27.7289
TE-5 CTRP2 4.8798 5.7527 4.8705 11.7723
KYSE-150 CTRP2 4.9709 5.8019 4.9619 11.165
TE-10 CTRP2 5.4534 6.5028 5.3803 8.1758
TE-1 CTRP2 5.4605 6.6946 5.3382 8.305
KYSE-70 CTRP2 5.6625 7.0347 5.4455 7.316
KYSE-140 CTRP2 5.8433 7.1632 5.5888 6.2641
KYSE-30 CTRP2 6.0099 6.4514 5.9935 4.275
TE-4 CTRP2 6.0886 9.7047 4.6292 9.5936
COLO 680N CTRP2 6.1074 6.7152 6.0375 3.8178
OE21 CTRP2 6.1349 6.7762 6.0474 3.7003
EC-GI-10 CTRP2 6.2382 6.8124 6.146 3.0337
TE-14 CTRP2 6.4479 8.8878 5.3547 5.8036
KYSE-410 CTRP2 6.4965 7.9829 5.8479 3.6376
OE19 CTRP2 6.5078 7.1536 6.2683 1.8605
KYSE-450 CTRP2 6.6325 7.4201 6.2462 1.6919
TE-6 CTRP2 6.6804 8.8372 5.5775 4.4079
KYSE-180 CTRP2 7.0256 8.7356 5.8966 2.4742
KYSE-520 CTRP2 7.3543 9.0757 5.9567 1.7687
KYSE-510 CTRP2 7.7548 9.2697 6.1004 0.8352
TE-11 CTRP2 8.1383 9.7643 6.0834 0.6138
TE-9 CTRP2 9.6084 16.0099 4.1403 5.9434
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 6.2491 6.8272 6.152 2.9801
KP-3 CTRP2 4.2779 5.7616 4.2384 15.8805
HuP-T4 CTRP2 4.5841 6.6934 4.3823 14.4159
PK-59 CTRP2 4.8917 5.9397 4.8681 11.7412
SNU-410 CTRP2 4.9918 5.8689 4.9792 11.0379
Panc 10.05 CTRP2 5.1186 6.856 4.9169 10.8658
BxPC-3 CTRP2 5.3117 6.6555 5.1868 9.3031
KP-4 CTRP2 5.3298 5.8996 5.3266 8.7566
MIA PaCa-2 CTRP2 5.6354 6.8926 5.4666 7.3151
Panc 08.13 CTRP2 5.7833 7.5407 5.3674 7.2894
YAPC CTRP2 5.7933 6.6337 5.7184 5.9223
HuP-T3 CTRP2 5.8898 7.111 5.6589 5.8664
Capan-2 CTRP2 5.9472 7.9124 5.3648 6.8848
PK-45H CTRP2 5.9785 6.8257 5.861 4.849
TCC-Pan2 CTRP2 5.9913 6.5848 5.9469 4.4969
Panc 02.03 CTRP2 6.0436 6.5542 6.0109 4.1077
Hs 766T CTRP2 6.0633 7.2359 5.7884 4.8953
PaTu 8988s CTRP2 6.0656 6.5816 6.0287 3.9763
Panc 05.04 CTRP2 6.1242 6.8663 6.0036 3.8956
PaTu 8988t CTRP2 6.199 6.5399 6.1823 3.0178
Panc 03.27 CTRP2 6.2124 6.8087 6.1196 3.2067
PSN1 CTRP2 6.5018 8.345 5.6721 4.3632
HPAC CTRP2 6.5088 7.3362 6.1796 2.2267
PaTu 8902 CTRP2 6.5482 7.5706 6.0985 2.4815
AsPC-1 CTRP2 6.5586 7.7746 6.006 2.8477
SU.86.86 CTRP2 6.5915 8.5175 5.663 4.2208
QGP-1 CTRP2 6.6474 9.1907 5.3734 5.3284
SNU-213 CTRP2 6.6847 7.7802 6.1093 2.1672
Panc 04.03 CTRP2 6.7871 7.9298 6.116 1.9555
KP-2 CTRP2 6.8376 7.6956 6.2694 1.236
HPAF-II CTRP2 6.8433 9.7263 5.2656 5.4145
L3.3 CTRP2 6.8571 8.5599 5.8572 2.9144
DAN-G CTRP2 7.8879 9.534 6.0566 0.8676
CFPAC-1 CTRP2 8.1156 9.6277 6.1275 0.5101
SUIT-2 CTRP2 8.4069 10.0222 6.1016 0.4256
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 6.5887 8.7948 5.5221 4.8182
Hs 934.T CTRP2 3.9458 5.7258 3.8898 18.1472
Hs 688(A).T CTRP2 4.0933 6.688 3.8481 17.8337
SK-MEL-1 CTRP2; CTRP1 4.1025 6.7735 3.8339 17.8575
G-361 CTRP2 4.3631 6.0021 4.2961 15.4081
COLO 792 CTRP2 4.377 6.1297 4.289 15.3882
A-375 CTRP2; CTRP1 4.6573 7.5477 4.176 14.9691
RPMI-7951 CTRP2 4.8446 6.3682 4.7481 12.3078
Hs 852.T CTRP2 4.9734 6.2356 4.9139 11.321
WM88 CTRP2 5.015 6.5105 4.9008 11.2373
MDA-MB-435S CTRP2 5.0676 6.4876 4.9636 10.8511
SK-MEL-5 CTRP2; CTRP1 5.1647 7.7479 4.6357 11.8016
Mel Ho CTRP2 5.225 6.7062 5.078 9.9593
WM1799 CTRP2 5.4252 7.6459 4.9509 9.8731
LOX-IMVI CTRP2 5.5555 6.5356 5.4839 7.4916
IGR-37 CTRP2 5.5868 6.8834 5.417 7.6408
Hs 940.T CTRP2 5.6313 7.4412 5.252 8.1457
IGR-39 CTRP2 5.6578 9.0431 4.5483 10.9047
WM793 CTRP2 5.9038 7.219 5.6297 5.9414
IPC-298 CTRP2 5.9191 6.4336 5.8988 4.893
Hs 294T CTRP2 5.9305 6.4361 5.9107 4.8152
MeWo CTRP2 5.9485 6.5148 5.9159 4.7399
WT2-iPS CTRP2 5.9971 6.5023 5.971 4.3938
WM266-4 CTRP2 6.0335 6.4076 6.0243 4.0937
COLO 800 CTRP2 6.0604 6.6075 6.0166 4.0355
UACC-257 CTRP2 6.0805 6.5416 6.0537 3.8414
HMCB CTRP2 6.1624 6.4502 6.1559 3.2265
COLO 829 CTRP2 6.1915 6.9251 6.0525 3.5211
Hs 895.T CTRP2 6.2536 6.8414 6.1514 2.9699
Hs 944.T CTRP2 6.291 8.0354 5.6358 4.9664
SK-MEL-28 CTRP2; CTRP1 6.3376 7.0765 6.1391 2.7948
K029AX CTRP2 6.344 7.3244 6.03 3.2211
Hs 839.T CTRP2 6.468 7.3571 6.1319 2.515
SK-MEL-30 CTRP2 6.5002 8.0182 5.8336 3.6904
CJM [Human melanoma] CTRP2 6.5048 7.0447 6.3184 1.6606
WM115 CTRP2 6.5333 7.2125 6.2629 1.8265
HT-144 CTRP2 6.5684 7.3982 6.2021 2.006
RVH-421 CTRP2 6.6743 7.9135 6.0342 2.5018
WM983B CTRP2 6.7721 8.7442 5.6985 3.7293
Mel JuSo CTRP2 6.9648 8.4789 5.9781 2.2344
UACC-62 CTRP2 6.9701 8.0286 6.2009 1.3173
A101D CTRP2 7.0348 8.3574 6.087 1.6834
A2058 CTRP2 7.2616 8.9676 5.9477 1.9247
IGR-1 CTRP2 7.3271 16.9274 2.0598 17.1846
SK-MEL-2 CTRP2 7.3277 8.544 6.185 0.9402
SK-MEL-31 CTRP2 7.3833 9.3853 5.8295 2.2291
Hs 936.T CTRP2 7.4959 9.5675 5.8164 2.1342
SK-MEL-3 CTRP2 7.7635 21.2657 0.2438 21.9387
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 CTRP2 4.2917 7.399 3.8371 17.2879
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SiMa CTRP2 1.5511 3.4812 1.5458 33.9137
MHH-NB-11 CTRP2 2.0749 3.4156 2.0742 30.412
SK-N-FI CTRP2 2.2993 3.3098 2.2992 28.9163
SK-N-DZ CTRP2 2.5237 3.3798 2.5237 27.4228
CHP-126 CTRP2 3.0109 4.9818 2.9802 24.2831
IMR-32 CTRP2 3.1295 3.5314 3.1295 23.3905
SK-N-BE(2) CTRP2 3.3928 4.4585 3.3916 21.642
Kelly CTRP2 4.1205 4.6866 4.1205 16.7947
NB1 CTRP2 4.211 5.5569 4.1884 16.2683
SK-N-SH CTRP2 4.3106 5.8714 4.2593 15.7034
KP-N-SI9s CTRP2 5.1418 6.344 5.0757 10.2239
NH-6 CTRP2 5.4199 7.501 5.0053 9.6758
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-245 CTRP2 4.1958 6.0667 4.1048 16.6047
SNU-1079 CTRP2 5.0571 6.4494 4.9612 10.8924
SNU-478 CTRP2 5.3335 7.3856 4.96 10.0876
HuCC-T1 CTRP2 5.7865 7.1499 5.5339 6.632
SNU-1196 CTRP2 5.8176 6.4663 5.7837 5.6156
SNU-869 CTRP2 6.1555 6.8677 6.0366 3.6822
HuH-28 CTRP2 6.2761 7.3385 5.957 3.6819
SNU-308 CTRP2 7.5776 9.8191 5.7506 2.2865
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-ES-1 CTRP2 3.186 3.8693 3.186 23.0148
TC71 CTRP2 3.2172 3.6209 3.2172 22.8072
CADO-ES1 CTRP2 3.3724 4.6017 3.3691 21.7849
A-673 CTRP2 3.3803 4.83 3.3709 21.7527
Hs 888.T CTRP2 3.4978 7.3406 2.9978 22.7086
G-292 clone A141B1 CTRP2 4.6477 6.1382 4.5797 13.5177
Hs 822.T CTRP2 4.8414 5.3479 4.8412 11.9974
SK-N-MC CTRP2 5.0183 5.5668 5.0176 10.8216
MHH-ES-1 CTRP2 5.0649 6.2264 5.0141 10.682
SJSA-1 CTRP2 5.6085 6.6266 5.5186 7.2045
SaOS-2 CTRP2 5.6844 6.4958 5.6332 6.5622
CAL-78 CTRP2 6.1156 7.4423 5.7495 4.9162
HOS CTRP2 6.1426 6.5325 6.1227 3.404
MG-63 CTRP2 6.1963 6.9971 6.0283 3.6018
SW1353 CTRP2 12.3694 24.8407 1.7589 10.7821
⏷ Show the Full List of 15 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 69 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CAL-148 CTRP2 3.0105 5.846 2.8646 24.6807
HCC1500 CTRP2 3.1735 4.0371 3.1734 23.0982
SK-BR-3 CTRP2 3.3585 6.0912 3.1928 22.4356
MDA-MB-361 CTRP2 3.7983 5.7716 3.7257 19.1856
MDA-MB-157 CTRP2 3.8219 5.6729 3.7648 18.9754
MCF-7 CTRP2; CTRP1 3.9379 6.6313 3.6942 18.861
HCC2218 CTRP2 4.2165 5.7135 4.1789 16.283
HMC-1-8 CTRP2 4.4402 5.0721 4.4399 14.668
AU565 CTRP2 4.6033 6.4638 4.4634 14.0663
CAL-51 CTRP2 4.6729 5.8537 4.6462 13.208
HCC38 CTRP2 4.8412 5.9381 4.8149 12.0867
BT-474 CTRP2 4.8803 5.9148 4.8585 11.8111
Hs 578Bst CTRP2 4.9915 6.3691 4.9075 11.2862
ZR-75-1 CTRP2 5.0779 6.1537 5.0394 10.5533
HCC1569 CTRP2 5.148 6.3849 5.0741 10.2101
MDA-MB-453 CTRP2 5.2843 6.8473 5.0999 9.702
HCC1143 CTRP2 5.2845 6.539 5.1876 9.3839
CAMA-1 CTRP2 5.4208 6.6528 5.3067 8.5392
HCC1954 CTRP2 5.4515 7.0902 5.1983 8.8499
HCC1395 CTRP2 5.5255 6.9138 5.3402 8.1052
HCC202 CTRP2 5.7362 7.9868 5.1203 8.394
HCC1419 CTRP2 5.8427 7.5854 5.4087 6.9717
T-47D CTRP2 5.865 8.7567 4.8844 9.041
EFM-192A CTRP2 5.8866 7.5368 5.475 6.5951
CAL-85-1 CTRP2 5.9216 6.9698 5.7477 5.4383
MDA-MB-468 CTRP2 5.9348 7.1583 5.6872 5.6339
BT-549 CTRP2 5.949 7.6679 5.4793 6.4188
JIMT-1 CTRP2 6.0306 6.9335 5.878 4.6365
HDQ-P1 CTRP2 6.0654 6.7527 5.9798 4.1545
HCC1428 CTRP2 6.0764 6.5412 6.0493 3.87
BT-20 CTRP2 6.0812 6.6393 6.031 3.9203
HCC1937 CTRP2 6.0878 6.8452 5.9722 4.1175
KPL-1 CTRP2 6.089 22.5238 -1.7631 29.669
MDA-MB-231 CTRP2 6.658 8.7337 5.6107 4.3114
ZR-75-30 CTRP2 7.3071 11.1843 4.8999 6.1383
HCC1806 CTRP2 7.425 9.3547 5.871 2.0121
BT 239 CTRP2 3.3401 4 3.3401 21.9891
BT 271 CTRP2 3.6803 4.832 3.6766 19.7368
BT 482 CTRP2 4.1408 11.6191 1.8529 24.9646
BT 428 CTRP2 4.4277 6.2516 4.32 15.1199
BT 504 CTRP2 4.4723 5.6227 4.456 14.5081
BT 231 CTRP2 4.7032 5.8783 4.6755 13.0097
BT 330 CTRP2 4.7628 6.1645 4.6992 12.7367
BT 228 CTRP2 4.8212 6.6946 4.6406 12.7638
BT 159 CTRP2 4.863 5.4962 4.8618 11.8568
BT 416 CTRP2 4.9254 6.7265 4.7453 12.0697
BT 286 CTRP2 4.9357 6.6546 4.7767 11.9251
BT 131 CTRP2 4.9479 6.1625 4.8987 11.4554
BT 112 CTRP2 4.9605 6.8277 4.7535 11.9346
BT 422 CTRP2 5.0731 26.9098 -4.8261 36.0863
BT 172 CTRP2 5.262 6.4653 5.1806 9.4782
BT 216 CTRP2 5.4005 6.5228 5.3179 8.5613
BT 145 CTRP2 5.5299 6.4299 5.4792 7.588
BT 245 CTRP2 5.5398 6.5009 5.4748 7.5726
BT164 CTRP2 5.7175 7.2845 5.4069 7.3108
BT 187 CTRP2 5.8113 7.4709 5.4265 6.9832
BT 340 CTRP2 5.8249 6.8712 5.6792 5.9726
BT 359 CTRP2 5.8488 7.6833 5.3713 7.1048
BT147 CTRP2 5.9103 6.7559 5.8102 5.2371
BT 498 CTRP2 5.9417 6.7204 5.8554 4.9779
BT 328 CTRP2 6.0692 6.6057 6.0267 3.9725
BT 179 CTRP2 6.1041 6.4694 6.0916 3.6348
BT 444 CTRP2 6.114 27.0007 -3.9794 33.1829
BT 333 CTRP2 6.1597 7.5324 5.7517 4.7982
BT 440 CTRP2 6.1829 6.5555 6.1619 3.1401
BT 232 CTRP2 6.3467 7.612 5.8942 3.7721
BT 224 CTRP2 6.3629 6.8547 6.2619 2.2438
BT 139 CTRP2 6.5133 7.5728 6.0666 2.6882
BT 320 CTRP2 8.0158 8.9924 6.3257 0.1321
⏷ Show the Full List of 69 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 5.6075 6.6896 5.5 7.275
Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D283 Med CTRP2 3.4558 4.6891 3.452 21.2313
LN-229 CTRP2; CTRP1 3.9139 6.1283 3.7879 18.6022
Daoy CTRP2 4.3321 5.4026 4.3237 15.4146
SW1783 CTRP2 4.8582 6.4578 4.7425 12.2851
SF539 CTRP2 4.8684 6.2252 4.8024 12.0422
YH-13 CTRP2 4.9002 6.5748 4.7593 12.0957
GB-1 CTRP2 4.9511 5.513 4.9505 11.2685
SNU-466 CTRP2 5.1189 6.018 5.0997 10.2145
CAS-1 CTRP2 5.2145 22.275 -2.3927 32.5233
U-118MG CTRP2 5.3625 7.2154 5.0564 9.6388
SF268 CTRP2 5.6814 6.696 5.5788 6.7661
KNS-60 CTRP2 5.7382 7.0796 5.5098 6.8587
DK-MG CTRP2 5.7849 6.4378 5.7536 5.8236
SNU-738 CTRP2 5.8712 6.5374 5.8271 5.2947
GOS-3 CTRP2 5.9307 7.1433 5.6891 5.6379
KALS-1 CTRP2 5.9747 7.3784 5.6351 5.7322
M059K CTRP2 5.9797 6.4304 5.9642 4.4727
SF126 CTRP2 5.9928 6.7992 5.8855 4.7163
TM-31 CTRP2 6.007 6.4334 5.9929 4.2866
Hs 683 CTRP2 6.1784 6.6772 6.1264 3.2808
GMS-10 CTRP2 6.2164 6.5255 6.2035 2.8889
A-172 CTRP2 6.3905 7.1055 6.1786 2.5043
8-MG-BA CTRP2 6.4683 7.2921 6.1639 2.3814
LN-18 CTRP2 6.5741 7.2191 6.2962 1.6005
Becker CTRP2 6.601 7.3736 6.2427 1.7693
CCF-STTG1 CTRP2 6.6124 7.3038 6.2873 1.5591
SNU-626 CTRP2 6.6127 7.8408 6.0192 2.6837
U-251MG CTRP2 6.7504 8.0562 6.0244 2.4032
U-87MG ATCC CTRP2 6.7793 8.6961 5.7283 3.5912
SW1088 CTRP2 6.8242 10.1403 5.0436 6.3799
KNS-81 CTRP2 6.841 8.8498 5.7006 3.5968
ONS-76 CTRP2 6.8916 8.6738 5.8272 2.9804
42-MG-BA CTRP2 6.9362 8.9064 5.746 3.243
SNU-1105 CTRP2 6.958 11.4981 4.4733 8.5186
SNU-489 CTRP2 7.2526 9.0903 5.8832 2.1935
GaMG CTRP2 7.3079 9.5786 5.6863 2.9067
SF295 CTRP2 7.4521 9.2896 5.9185 1.7946
KG-1-C CTRP2 7.48 9.8196 5.6871 2.6627
DBTRG-05MG CTRP2 7.6282 10.4657 5.4779 3.2916
SNB-75 CTRP2 7.8886 10.4593 5.6466 2.3087
T98G CTRP2 7.9821 9.8119 5.9871 1.0128
NMC-G1 CTRP2 8.3017 9.7236 6.1708 0.3201
SNU-201 CTRP2 9.1809 17.3159 3.2455 9.8429
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-1 CTRP2 3.3515 4.5304 3.3492 21.9205
JHUEM-2 CTRP2; CTRP1 3.5417 5.3724 3.5024 20.7796
MFE-296 CTRP2 3.7864 5.2249 3.77 19.0732
JHUEM-3 CTRP2 4.6057 9.8666 3.1279 19.1603
AN3-CA CTRP2 4.6153 6.0456 4.56 13.6894
JHUEM-7 CTRP2 4.6668 6.5907 4.5006 13.7381
ESS-1 CTRP2 4.7407 6.9565 4.4739 13.6134
HEC-1-A CTRP2 4.7596 6.3634 4.6567 12.8956
KLE CTRP2 4.9132 6.3927 4.8173 11.8492
HEC-6 CTRP2 4.9372 6.1234 4.8933 11.5083
RL95-2 CTRP2 5.2548 6.0651 5.2381 9.3013
HEC-151 CTRP2 5.3481 5.9525 5.3431 8.6409
HEC-59 CTRP2 5.5576 7.0081 5.3422 8.0047
HEC-1-B CTRP2 5.5912 6.4408 5.5434 7.1703
HEC-251 CTRP2 5.615 6.334 5.5879 6.9398
HEC-108 CTRP2 5.6915 6.3439 5.6684 6.4167
EFE-184 CTRP2 5.8909 6.8779 5.7481 5.5241
HEC-50B CTRP2 5.982 7.6002 5.5433 6.0794
HEC-265 CTRP2 6.6135 7.5376 6.1714 2.0432
EN CTRP2 6.6998 7.7503 6.1365 2.0251
MFE-319 CTRP2 7.3192 9.0459 5.9483 1.8465
Ishikawa (Heraklio) 02 ER- CTRP2 6.5246 7.5881 6.069 2.6541
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 19 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR14TKB CTRP2 1.7156 3.6729 -1.9899 0.396
RCC10RGB CTRP2 5.1058 5.5705 5.1055 10.2376
UO-31 CTRP2 5.1531 7.0361 4.8952 10.8447
769-P CTRP2 5.9262 6.5983 5.8726 4.9626
ACHN CTRP2 5.982 6.7069 5.9034 4.6825
TUHR4TKB CTRP2 6.0215 8.6969 5.0616 7.9503
KMRC-2 CTRP2 6.1603 6.4972 6.1478 3.2609
KMRC-3 CTRP2 6.1901 8.3892 5.3692 6.2973
VMRC-RCZ CTRP2 6.2682 6.7813 6.1896 2.784
786-O CTRP2 6.3101 6.9874 6.1507 2.8195
KMRC-1 CTRP2 6.4007 7.1648 6.1607 2.5519
TUHR10TKB CTRP2 6.7098 9.9929 5.024 6.6757
BFTC-909 CTRP2 6.8728 8.2069 6.0439 2.1108
VMRC-RCW CTRP2 6.9513 10.0967 5.1665 5.6354
OS-RC-2 CTRP2 6.9854 8.79 5.8404 2.7696
Caki-1 CTRP2 7.537 10.1756 5.5554 3.1083
KMRC-20 CTRP2 7.5828 10.003 5.6675 2.6036
Caki-2 CTRP2 7.6913 9.1627 6.1131 0.8468
SNU-1272 CTRP2 7.7921 10.2638 5.6778 2.3039
⏷ Show the Full List of 19 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-175 CTRP1 1.1489 3.3788 1.1399 75.5983
CW-2 CTRP2; CTRP1 2.0357 4.3295 2.0107 30.7538
SNU-81 CTRP1 2.2692 4.4481 2.2454 61.6967
SNU-C1 CTRP2 2.8855 5.8428 2.7299 25.545
HT115 CTRP2; CTRP1 2.951 4.1499 2.9497 24.583
CL-34 CTRP1 3.1787 5.1997 3.1371 49.5247
SW48 CTRP2 3.3039 4.7018 3.2973 22.2518
LoVo CTRP2; CTRP1 3.3396 5.2889 3.2978 22.1329
NCI-H747 CTRP2 3.3856 7.6212 2.7802 23.8299
CL-40 CTRP1 3.4539 5.1473 3.4297 45.667
NCI-H508 CTRP2; CTRP1 3.5569 5.5938 3.4928 20.7628
COLO 320 CTRP2; CTRP1 3.694 7.9093 3.0081 22.0953
SNU-61 CTRP2; CTRP1 3.8607 5.5308 3.8226 18.6524
SNU-C5 CTRP2; CTRP1 3.9919 6.3293 3.8291 18.2129
HT-55 CTRP2; CTRP1 4.0086 6.0713 3.9016 17.9056
SW948 CTRP2; CTRP1 4.0528 6.4805 3.8591 17.9181
MDST8 CTRP2; CTRP1 4.0812 5.883 4.0121 17.291
CCK-81 CTRP2 4.2221 5.381 4.2115 16.1543
LS123 CTRP2; CTRP1 4.3244 5.5998 4.3034 15.5084
T84 CTRP2 4.3511 5.5519 4.3348 15.3145
COLO 678 CTRP2; CTRP1 4.4124 7.4017 3.9664 16.4565
SW480 CTRP1 4.5125 6.2196 4.4184 31.1191
LS1034 CTRP2 4.5256 6.4556 4.3807 14.6007
GP2d CTRP2 4.5903 6.1743 4.5113 13.9378
SNU-407 CTRP2 4.5999 6.0319 4.5456 13.7886
LS513 CTRP2 4.6173 5.8956 4.5826 13.6054
SNU-C2A CTRP2 4.6218 5.9691 4.578 13.6067
CL-11 CTRP2 4.6842 6.0735 4.6296 13.2285
SNU-1040 CTRP1 4.6922 6.0762 4.6378 28.2744
RCM-1 [Human ESC] CTRP2; CTRP1 4.7135 6.4396 4.5892 13.2779
RKO CTRP2; CTRP1 4.9667 6.7659 4.7788 11.824
SNU-1033 CTRP2 4.9687 6.5716 4.835 11.6147
SK-CO-1 CTRP2 5.0283 6.8677 4.815 11.5076
SNU-C4 CTRP2; CTRP1 5.06 7.6237 4.5755 12.3201
KM12 CTRP2; CTRP1 5.1319 7.0752 4.8587 11.0423
COLO205 CTRP2 5.501 8.2187 4.7782 10.3582
HCT 15 CTRP2 5.6108 6.8115 5.4666 7.3872
OUMS-23 CTRP2 5.6214 6.3195 5.5969 6.8884
HT-29 CTRP2; CTRP1 5.626 7.8432 5.0732 8.863
LS180 CTRP2 5.6396 6.9364 5.456 7.3421
HCT 116 CTRP2; CTRP1 5.6611 8.3922 4.8586 9.6351
HCT 8 CTRP2; CTRP1 5.8184 8.7998 4.8191 9.4183
SW620 CTRP2; CTRP1 5.8207 8.392 5.0156 8.61
COLO201 CTRP2 5.842 6.6345 5.7713 5.5838
SW1417 CTRP2 5.9819 6.8097 5.8702 4.8049
HCC-56 CTRP2 5.9913 6.5227 5.9607 4.4483
DLD-1 CTRP2 6.0211 6.5008 5.9973 4.2264
C2BBe1 CTRP2 6.1456 6.8605 6.0287 3.7401
LS411N CTRP2 6.7193 8.4636 5.7961 3.4172
NCI-H716 CTRP2 6.9308 8.4138 5.9851 2.2596
SNU-503 CTRP2 7.8717 9.6733 5.9886 1.1017
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-182 CTRP2 3.9247 5.8773 3.845 18.3693
JHH-2 CTRP2 4.7247 7.8242 4.1404 14.9169
SNU-761 CTRP2 4.9969 6.1598 4.9518 11.1151
Hep 3B2.1-7 CTRP2 5.3099 6.031 5.2988 8.9155
Hep-G2 CTRP2; CTRP1 5.3949 7.1562 5.1132 9.332
JHH-5 CTRP2 5.4191 9.2448 4.2211 12.8067
HLF CTRP2 5.4431 8.4468 4.6163 11.1525
SNU-398 CTRP2 5.6345 6.7085 5.524 7.1067
JHH-4 CTRP2 5.6494 6.4455 5.6056 6.769
SNU-423 CTRP2 5.8283 6.6994 5.738 5.7456
SNU-449 CTRP2 5.9545 7.2023 5.6897 5.571
Li-7 CTRP2 6.265 7.9634 5.6468 4.9797
SK-HEP-1 CTRP2 6.5933 7.4084 6.2186 1.8855
SNU-886 CTRP2 6.643 10.1067 4.1803 4.7834
SNU-387 CTRP2 6.6571 7.8197 6.067 2.3971
JHH-1 CTRP2 6.6978 7.6134 6.2033 1.7488
PLC/PRF/5 CTRP2 6.7379 7.5998 6.2418 1.5153
SNU-878 CTRP2 6.9981 8.7475 5.8707 2.6242
SNU-475 CTRP2 7.2659 8.4462 6.1932 0.9765
JHH-6 CTRP2 7.689 8.8678 6.235 0.4759
HuH-1 CTRP2 8.1983 9.6145 6.1688 0.3684
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 141 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1876 CTRP1 1.1581 4.294 1.0982 72.7403
NCI-H1836 CTRP1 1.3369 3.148 1.3343 74.4121
NCI-H1694 CTRP2; CTRP1 1.5365 3.5759 1.529 34.0181
NCI-H1105 CTRP2; CTRP1 2.0693 4.8839 1.9992 30.6807
NCI-H211 CTRP2 2.0797 4.1406 2.0653 30.4257
COR-L23 CTRP1 2.1486 4.6469 2.1058 62.8244
NCI-H526 CTRP2 2.4651 4.2519 2.4556 27.8442
NCI-H596 CTRP1 2.5143 4.2204 2.5068 58.7761
COR-L95 CTRP2 3.0421 5.056 3.0067 24.0912
HCC1359 CTRP1 3.0492 4.9193 3.0246 51.309
NCI-H2029 CTRP2 3.0949 3.925 3.0949 23.6209
NCI-H69 CTRP2 3.1088 5.9834 2.9442 24.0921
NCI-H1184 CTRP2 3.1463 5.0074 3.1195 23.3687
NCI-H1341 CTRP2 3.3044 4.8149 3.2938 22.2619
DMS 53 CTRP2 3.3074 4.9546 3.2901 22.2645
NCI-H2081 CTRP2; CTRP1 3.4441 5.2249 3.4134 21.3996
NCI-H2106 CTRP2 3.5625 4.9534 3.5528 20.5411
NCI-H1781 CTRP1 3.5639 4.75 3.5603 44.02
DMS 79 CTRP2 3.7046 4.6741 3.7035 19.5666
DMS 454 CTRP2 3.9396 5.5879 3.8998 18.1329
NCI-H446 CTRP2 4.0504 5.3969 4.0328 17.3202
DV-90 CTRP2 4.1183 5.9289 4.0448 17.0596
NCI-H3255 CTRP1 4.2223 5.0792 4.2208 34.6047
NCI-H1395 CTRP2 4.2599 8.9172 3.1991 19.7978
NCI-H2286 CTRP2 4.2665 6.8784 3.9817 16.8273
IA-LM CTRP2 4.2712 4.99 4.2707 15.7933
COLO 699 CTRP2; CTRP1 4.277 6.765 4.0267 16.632
NCI-H841 CTRP2; CTRP1 4.2928 6.1673 4.1907 15.9981
NCI-H1581 CTRP2 4.3926 5.2195 4.3907 14.9902
NCI-H2073 CTRP1 4.4019 6.2769 4.2867 32.8329
DMS 273 CTRP2 4.4141 6.417 4.2685 15.3446
HCC2108 CTRP2; CTRP1 4.4569 6.4412 4.3093 15.0671
HCC1588 CTRP2 4.4696 5.9888 4.4125 14.6652
NCI-H1435 CTRP2 4.5354 6.7256 4.3199 14.7891
COR-L88 CTRP2 4.5636 6.9926 4.2696 14.8888
NCI-H1155 CTRP2 4.5681 5.5165 4.5612 13.8387
NCI-H1734 CTRP2 4.5939 5.9192 4.5548 13.7761
Calu-6 CTRP2 4.6165 6.0097 4.5667 13.6625
HCC4006 CTRP2; CTRP1 4.6175 6.9443 4.3437 14.4569
Sq-1 CTRP2; CTRP1 4.6756 5.9049 4.6434 13.209
HOP-92 CTRP2 4.6766 6.9432 4.4082 14.0446
HCC827 CTRP2; CTRP1 4.7352 6.452 4.61 13.1369
NCI-H2342 CTRP2; CTRP1 4.7511 8.9553 3.6871 16.6112
NCI-H1650 CTRP2 4.8201 5.7897 4.8062 12.1848
EPLC-272H CTRP2 4.846 6.1843 4.7854 12.1728
NCI-H1666 CTRP2 4.8609 6.2981 4.7803 12.1433
NCI-H522 CTRP2 5.0221 6.907 4.7957 11.5973
NCI-H23 CTRP2 5.0334 6.4163 4.9428 11.0308
HCC1833 CTRP2; CTRP1 5.0517 7.3353 4.6783 11.9506
SK-LU-1 CTRP2; CTRP1 5.0939 7.3879 4.7036 11.7355
NCI-H2087 CTRP2 5.0963 7.019 4.8394 11.2176
NCI-H441 CTRP2; CTRP1 5.1221 8.4142 4.3058 13.2091
HCC78 CTRP2 5.1959 6.8856 4.9916 10.3621
LCLC-97TM1 CTRP2 5.2156 6.9283 4.9991 10.2764
NCI-H1975 CTRP2 5.253 6.3713 5.1908 9.4706
HCC15 CTRP2; CTRP1 5.2933 9.0029 4.2108 13.1555
HCC1195 CTRP2; CTRP1 5.2945 6.8796 5.1008 9.6687
SHP-77 CTRP2 5.3034 6.8045 5.1342 9.5197
NCI-H650 CTRP2 5.3205 7.0184 5.0824 9.661
NCI-H520 CTRP2 5.3607 6.5517 5.2676 8.8636
CAL-12T CTRP2; CTRP1 5.3697 7.4586 4.9694 9.9518
DMS 114 CTRP2 5.4081 7.0831 5.1541 9.1404
Lu-99 CTRP2 5.4381 6.8789 5.257 8.6695
Calu-1 CTRP2 5.4382 6.4614 5.373 8.2492
HCC44 CTRP2 5.445 6.9498 5.2408 8.7092
SBC-5 CTRP2 5.4834 6.1503 5.4704 7.7675
COLO 668 CTRP2 5.5004 7.3839 5.1376 8.9444
NCI-H1299 CTRP2 5.5195 7.0497 5.2862 8.3245
Calu-3 CTRP2 5.5934 6.9311 5.408 7.6554
HCC2279 CTRP2 5.6267 6.5773 5.5512 7.0322
NCI-H2291 CTRP2 5.64 7.3974 5.2792 8.0161
NCI-H2196 CTRP2 5.6579 7.8057 5.1224 8.5853
NCI-H2085 CTRP2 5.6677 7.1152 5.4209 7.3949
NCI-H661 CTRP2 5.6889 6.8721 5.5315 6.9177
HCC2935 CTRP2; CTRP1 5.698 8.43 4.8775 9.4685
EBC-1 CTRP2 5.7012 7.4414 5.3249 7.6736
SW1271 CTRP2 5.7185 7.2182 5.4347 7.2008
VMRC-LCD CTRP2 5.7211 6.6357 5.639 6.4281
RERF-LC-A1 CTRP2 5.7451 6.4804 5.7023 6.1288
NCI-H2009 CTRP2 5.765 6.6217 5.6907 6.1081
NCI-H2405 CTRP2 5.7786 7.937 5.1855 8.0259
RERF-LC-Ad2 CTRP2 5.85 7.0212 5.6516 6.0052
HCC1171 CTRP2 5.8505 6.8146 5.7261 5.7237
NCI-H226 CTRP2 5.8605 6.7017 5.7724 5.5238
NCI-H292 CTRP2 5.8667 6.9477 5.6969 5.7863
NCI-H1568 CTRP2 5.9148 7.05 5.7096 5.6026
NCI-H358 CTRP2 5.9748 7.3773 5.6356 5.7301
NCI-H1703 CTRP2 5.9866 6.6623 5.9215 4.6028
HCC366 CTRP2 6.0177 6.9655 5.852 4.7716
NCI-H1755 CTRP2; CTRP1 6.0233 7.6115 5.5796 5.8299
COR-L105 CTRP2 6.0288 9.1476 4.8486 8.8148
MOR/CPR CTRP2 6.0405 7.3861 5.6989 5.3089
SK-MES-1 CTRP2 6.0801 6.8362 5.9671 4.1588
ChaGo-K-1 CTRP2 6.1375 6.8195 6.035 3.7392
NCI-H2030 CTRP2; CTRP1 6.1709 7.6137 5.7246 4.8806
NCI-H1563 CTRP2 6.1781 7.2827 5.8848 4.2164
NCI-H1838 CTRP2 6.191 7.9955 5.5614 5.5013
NCI-H727 CTRP2 6.3168 8.0581 5.6486 4.856
T3M-10 CTRP2; CTRP1 6.3597 9.861 4.7928 8.3381
HCC1438 CTRP2 6.3619 8.503 5.47 5.5014
NCI-H838 CTRP2 6.4231 6.9873 6.2656 2.0724
NCI-H2122 CTRP2; CTRP1 6.4655 8.8166 5.4055 5.5547
RERF-LC-Ad1 CTRP2 6.4956 6.9848 6.3382 1.6014
LXF 289 CTRP2 6.5619 8.4847 5.6543 4.3161
LUDLU-1 CTRP2 6.5642 7.4372 6.179 2.1112
NCI-H1869 CTRP2 6.5839 7.562 6.1339 2.2601
NCI-H2172 CTRP2; CTRP1 6.5849 8.2817 5.7754 3.7623
NCI-H1339 CTRP2 6.5981 7.2892 6.2823 1.6086
NCI-H1573 CTRP2 6.6328 8.0923 5.9104 3.1013
NCI-H1915 CTRP2 6.68 7.7339 6.1287 2.0947
LK2 CTRP2 6.7081 7.4301 6.3029 1.3127
HARA [Human squamous cell lung carcinoma] CTRP2 6.7182 8.8177 5.6182 4.1658
RERF-LC-MS CTRP2 6.7312 7.8505 6.1117 2.0717
NCI-H1623 CTRP2 6.8091 8.2629 5.9676 2.5368
LOU-NH91 CTRP2 6.8798 8.9479 5.6821 3.6062
HCC95 CTRP2 6.9174 8.8278 5.7707 3.1719
NCI-H2126 CTRP2 6.9845 8.8803 5.7953 2.9578
NCI-H2170 CTRP2 6.9944 8.3032 6.0851 1.7506
LC-1/sq-SF CTRP2 7.0199 8.3468 6.0817 1.7264
A-549 CTRP2 7.1123 9.1858 5.739 2.986
NCI-H196 CTRP2 7.12 10.7141 4.9907 6.0758
NCI-H460 CTRP2; CTRP1 7.1216 8.854 5.9072 2.2848
NCI-H1793 CTRP2 7.1245 9.3153 5.6844 3.1913
NCI-H1355 CTRP2 7.2805 10.3717 5.2802 4.6092
NCI-H2228 CTRP2 7.3847 10.1346 5.4707 3.668
NCI-H2023 CTRP2; CTRP1 7.3933 9.4329 5.8135 2.2787
HOP-62 CTRP2 7.4349 9.5838 5.7693 2.3979
LCLC-103H CTRP2 7.5051 10.1973 5.5235 3.2802
KNS-62 CTRP2 7.6286 8.9555 6.1689 0.7187
PC-14 CTRP2 7.7183 12.1003 4.751 6.0966
NCI-H1373 CTRP2 7.7242 16.0883 2.789 13.8549
NCI-H322 CTRP2 7.7395 9.2564 6.0981 0.855
NCI-H1944 CTRP2 7.8608 9.6401 5.9971 1.0829
BEN CTRP2 7.9607 8.8005 6.3729 0.0799
EKVX CTRP2 8.159 11.3963 5.3802 2.9978
NCI-H2110 CTRP2; CTRP1 8.2003 10.4547 5.8259 1.3545
NCI-H647 CTRP2 8.2898 10.2269 5.9671 0.8436
SW1573 CTRP2 9.2207 11.0829 6.0364 0.2634
NCI-H1792 CTRP2 10.4963 17.3081 4.0771 5.1855
Lu-65 CTRP2 10.8813 23.8886 1.2461 14.1872
Hs 888.Lu CTRP2 5.8227 10.0561 4.2129 11.9022
⏷ Show the Full List of 141 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 3.0857 5.3517 3.0222 23.8968
SYO-1 CTRP2 4.5871 5.7875 4.5624 13.7723
H-STS CTRP2 4.712 6.7087 4.5175 13.54
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 3.8637 5.0686 3.8569 18.5267
OVK18 CTRP2; CTRP1 1.719 2.7231 1.7189 32.7788
COV434 CTRP2; CTRP1 2.4211 4.0712 2.4157 28.1236
RMUG-S CTRP1 2.6124 4.4864 2.5974 57.3307
RMG-I CTRP2; CTRP1 3.6058 6.3729 3.3982 20.9391
SNU-119 CTRP2 4.0301 6.6849 3.7801 18.2711
TYK-nu CTRP2; CTRP1 4.1193 7.2603 3.6988 18.3032
A2780 CTRP2 4.1474 5.6727 4.1103 16.7409
FU-OV-1 CTRP2 4.1992 5.7029 4.1618 16.3969
EFO-27 CTRP2; CTRP1 4.2976 6.0595 4.2159 15.895
ONCO-DG-1 CTRP2 4.4904 5.3334 4.4876 14.3424
SNU-840 CTRP2; CTRP1 4.6813 6.8635 4.4383 13.9203
COV644 CTRP2; CTRP1 4.6918 6.6977 4.4986 13.6692
OC 314 CTRP2 4.6943 5.8969 4.6641 13.0778
Caov-3 CTRP2; CTRP1 4.7611 6.8035 4.5434 13.2981
OVSAHO CTRP2 4.8976 6.0692 4.8587 11.7547
OVCAR-4 CTRP2 4.9024 5.9341 4.8799 11.6666
OAW28 CTRP2 5.3206 7.1512 5.0352 9.8378
JHOC-5 CTRP2; CTRP1 5.3287 7.0251 5.0889 9.613
Kuramochi CTRP2 5.3595 6.4013 5.3002 8.7516
DOV13 CTRP2 5.375 6.9095 5.1785 9.1449
OV7 CTRP2; CTRP1 5.4087 6.8909 5.2211 8.8884
HEY A8 CTRP2 5.5742 6.7715 5.4393 7.596
COV362 CTRP2; CTRP1 5.709 6.7046 5.6064 6.5832
OV-90 CTRP2; CTRP1 5.7135 7.1477 5.4572 7.1285
ES2 CTRP2 5.7319 6.9963 5.5342 6.7841
IGROV-1 CTRP2 5.7378 7.0096 5.5357 6.7615
OVCAR-5 CTRP2 5.8204 7.4504 5.4448 6.887
JHOM-1 CTRP2; CTRP1 5.8248 7.7757 5.3053 7.4293
TOV-21G CTRP2 5.8786 7.5761 5.4495 6.7173
TOV-112D CTRP2 5.8903 6.6086 5.8309 5.2221
OV56 CTRP2 5.9189 6.4289 5.8993 4.8918
OVTOKO CTRP2 6.0459 12.361 3.2729 15.2266
MCAS CTRP2 6.0573 7.5764 5.6297 5.5435
SNU-8 CTRP2 6.0642 6.5888 6.0254 3.9926
JHOS-2 CTRP2 6.1101 6.5445 6.0851 3.6385
OAW42 CTRP2; CTRP1 6.6056 7.8203 6.0234 2.6801
OVCAR-8 CTRP2 6.6928 8.4054 5.8036 3.4354
EFO-21 CTRP2 6.7616 7.6643 6.2281 1.5317
OVISE CTRP2 6.8749 8.2755 6.0117 2.2411
SK-OV-3 CTRP2 7.751 11.6214 5.0064 5.0107
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 21 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 4.0959 5.6043 4.0631 17.0691
Yamato-SS CTRP2 4.8835 5.6877 4.8776 11.7362
G-401 CTRP2 3.0046 4.8015 2.9857 24.2851
TTC-709 CTRP2 3.1149 3.6128 3.1149 23.4876
TE 617.T CTRP2 3.2959 4.7397 3.2879 22.31
KYM-1 CTRP2 3.6707 4.9293 3.6644 19.8094
BT-12 CTRP2 3.6896 4.5691 3.6891 19.6646
Rh41 CTRP2 3.7556 4.5566 3.7553 19.2243
GCT CTRP2 4.2636 6.2219 4.1481 16.2393
SW982 CTRP2 4.4088 6.2342 4.3031 15.2389
A-204 CTRP2 4.6368 6.1345 4.5686 13.5912
RKN CTRP2 4.6545 5.9131 4.62 13.3573
RD CTRP2 4.8255 6.6935 4.6456 12.7329
G-402 CTRP2 4.8695 6.6912 4.6943 12.4233
Rh18 CTRP2 4.9145 5.9369 4.8924 11.5842
HT-1080 CTRP2; CTRP1 5.7201 8.0678 5.0671 8.6483
Tm87-16 CTRP2 5.7638 7.3443 5.431 7.092
Hs 729.T CTRP2 5.9849 9.5536 4.6089 9.9055
SK-UT-1 CTRP2 5.9939 6.6499 5.9329 4.5392
MES-SA CTRP2 6.5119 7.16 6.2689 1.8488
BT-16 CTRP2 6.7745 7.8457 6.1481 1.8431
⏷ Show the Full List of 21 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 5.9332 8.8954 4.8822 8.8926
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP2 4.4936 6.2241 4.3971 14.6423
NCI-H28 CTRP2 4.909 6.1804 4.8539 11.7345
NCI-H2052 CTRP2 5.8674 7.8032 5.3357 7.2006
IST-Mes1 CTRP2 5.9449 6.8547 5.8146 5.1196
NCI-H2452 CTRP2 6.001 7.4379 5.6356 5.6626
ACC-MESO-1 CTRP2 6.9589 8.4512 5.9874 2.2054
JL-1 CTRP2 8.5334 11.5278 5.5388 2.0236
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VCaP CTRP2 4.7616 6.6326 4.5927 13.1178
22Rv1 CTRP2 5.2104 6.4452 5.1289 9.8215
LNCaP clone FGC CTRP2 6.2225 7.1009 6.011 3.6002
DU145 CTRP2 6.5274 7.548 6.0914 2.555
PaCa-3 CTRP2 6.7895 7.6919 6.2357 1.4526
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-15 CTRP2 5.5671 6.8843 5.3953 7.7793
A-253 CTRP2 6.1216 6.8041 6.0233 3.8289
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-16 CTRP2 3.1828 3.665 3.1828 23.0358
HGC-27 CTRP2 3.2001 4.924 3.1809 22.9848
ECC10 CTRP2 3.4879 5.3608 3.4468 21.1436
GSS CTRP2 4.2829 5.8645 4.2307 15.8905
NCI-N87 CTRP2 4.5853 6.3063 4.4796 14.0649
SNU-216 CTRP2 4.8421 6.0805 4.7978 12.1421
SNU-5 CTRP2 5.246 7.8749 4.6675 11.4593
Fu97 CTRP2 5.3113 7.2249 4.9979 10.0053
GSU CTRP2 5.4096 5.8487 5.4087 8.2179
SNU-620 CTRP2 5.4658 6.3751 5.4203 7.9964
SNU-719 CTRP2 5.6148 7.052 5.3879 7.6691
SNU-601 CTRP2 5.6851 6.8038 5.5499 6.8609
KE-39 CTRP2 5.6854 8.8593 4.6626 10.3724
23132/87 CTRP2 5.8308 6.5146 5.7881 5.5585
NUGC-3 CTRP2 5.8492 7.0907 5.6239 6.113
MKN7 CTRP2 5.869 11.6822 3.453 14.8922
MKN1 CTRP2 5.8937 9.6825 4.4616 10.7181
SNU-1 CTRP2 5.9048 6.655 5.8343 5.1656
HuG1-N CTRP2 6.0749 6.6679 6.0163 3.9924
AGS CTRP2 6.0766 6.5554 6.0465 3.8792
SNU-668 CTRP2 6.0789 6.8386 5.965 4.1704
MKN74 CTRP2 6.0938 7.1089 5.8743 4.4773
LMSU CTRP2 6.1361 6.605 6.0998 3.5053
Hs 746.T CTRP2 6.1707 6.6236 6.1329 3.2808
IM95 CTRP2 6.1952 6.8866 6.0717 3.4375
NUGC-4 CTRP2 6.5264 8.5463 5.593 4.6447
ECC12 CTRP2 7.2191 9.4246 5.6988 2.9872
MKN45 CTRP2 7.5668 8.5631 6.3008 0.3706
SH-10-TC CTRP2 7.6226 9.2098 6.0555 1.1035
SNG-M CTRP2 5.8159 6.6952 5.7257 5.8277
SNU-1077 CTRP2 5.8635 8.6964 4.9119 8.9317
SNU-685 CTRP2 6.4128 7.4494 6.0354 3.0385
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8305C CTRP2 4.6501 6.4434 4.5193 13.7225
8505C CTRP2 4.8745 5.8989 4.854 11.8454
B-CPAP CTRP2 4.8929 6.4865 4.7735 12.0674
CAL-62 CTRP2 4.9102 6.0306 4.8772 11.6502
ML-1 [Human leukemia] CTRP2 5.4323 11.636 3.0779 17.3464
BHT-101 CTRP2 5.6772 7.1601 5.4138 7.3954
FTC-238 CTRP2 5.759 6.8797 5.6049 6.4409
CGTH-W-1 CTRP2 5.8802 6.7396 5.7825 5.428
SW579 CTRP2 6.0177 6.408 6.0075 4.2021
FTC-133 CTRP2 6.0509 6.4959 6.0303 4.0171
TT CTRP2 6.522 7.4641 6.1282 2.4122
TT2609-C02 CTRP2 7.3481 10.2538 5.3868 4.0658
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SCC-25 CTRP2 4.9106 6.0495 4.8752 11.6559
YD-8 CTRP2 5.1717 5.8914 5.1645 9.8223
SCC-4 CTRP2 5.2951 6.7472 5.1424 9.5143
SNU-1214 CTRP2 5.4202 7.2549 5.103 9.2996
YD-10B CTRP2 5.8008 7.1005 5.5686 6.4592
PE/CA-PJ49 CTRP2 5.8203 6.4534 5.789 5.5882
HSC-3 CTRP2 5.8445 6.8523 5.7068 5.8125
SNU-1076 CTRP2 5.8752 6.4139 5.8547 5.1857
SNU-1041 CTRP2 5.9538 6.5134 5.922 4.7019
HSC-4 CTRP2 6.0602 6.5391 6.0322 3.981
FaDu CTRP2 6.1157 6.5325 6.0936 3.5908
PE/CA-PJ34 (clone C12) CTRP2 6.1276 6.5524 6.1025 3.5224
PE/CA-PJ15 CTRP2 6.135 6.6238 6.0939 3.53
BICR 6 CTRP2 6.1536 6.4743 6.1438 3.2964
BICR 31 CTRP2 6.1779 6.7306 6.1092 3.3454
BHY CTRP2 6.1843 7.2167 5.9208 4.0567
SNU-899 CTRP2 6.195 6.7881 6.1082 3.2997
SNU-46 CTRP2 6.2024 6.7534 6.1283 3.2031
CAL-27 CTRP2 6.2453 6.7085 6.1896 2.8502
SCC-9 CTRP2 6.247 6.8206 6.1523 2.9846
HSC-2 CTRP2 6.2619 6.67 6.2196 2.6911
CAL-33 CTRP2 6.4584 8.5122 5.551 4.96
Detroit 562 CTRP2 6.4734 8.1715 5.7337 4.164
BICR 18 CTRP2 6.5128 7.3835 6.1598 2.3004
BICR 22 CTRP2 6.6905 7.6709 6.1687 1.907
SNU-1066 CTRP2 6.7156 8.292 5.8787 3.0773
BICR 16 CTRP2 6.9277 8.4733 5.9535 2.3954
BICR 56 CTRP2 7.6656 10.3899 5.5386 3.0015
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JMSU-1 CTRP2 4.4771 5.2958 4.4749 14.4287
CAL-29 CTRP2 4.8906 5.7074 4.884 11.6911
RT-4 CTRP2 4.9943 7.3481 4.612 12.3643
UM-UC-3 CTRP2 5.0101 5.7697 5.004 10.8944
U-BLC1 CTRP2 5.1643 7.0117 4.9156 10.7363
RT-112 CTRP2 5.3486 6.3034 5.3066 8.7637
SW1710 CTRP2 5.4379 6.875 5.2581 8.6657
BFTC-905 CTRP2 5.4422 6.1748 5.4245 8.0578
253J CTRP2 5.7952 6.64 5.7188 5.9153
VM-CUB-1 CTRP2 5.7959 6.6347 5.7209 5.9055
647V CTRP2 5.828 6.9059 5.6703 5.9972
TCCSUP CTRP2 5.8379 6.7266 5.7404 5.7084
T24 CTRP2 6.0283 6.5462 5.996 4.2083
253J-BV CTRP2 6.0585 7.3845 5.718 5.187
KMBC-2 CTRP2 6.06 7.4728 5.6796 5.3363
HT-1376 CTRP2 6.0815 6.8927 5.9479 4.2276
SCaBER CTRP2 6.0886 6.5076 6.0689 3.7629
5637 CTRP2 6.1081 7.9503 5.5039 5.9313
HT-1197 CTRP2 6.1867 6.6664 6.1385 3.2119
UM-UC-1 CTRP2 6.2406 7.0013 6.0727 3.3097
639V CTRP2 6.4752 7.7417 5.9487 3.2616
J82 CTRP2 6.8154 8.2153 5.9961 2.4067
BC-3C CTRP2 7.1078 8.5237 6.0569 1.7008
KU-19-19 CTRP2 7.1443 8.5503 6.0685 1.6043
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HeLa CTRP2 7.1598 9.0323 5.8475 2.4706

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