Details of the Drug

General Information of Drug (ID: DMM0LRE)

Drug Name
TGX-221
Synonyms TGX 221
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 364.4
Logarithm of the Partition Coefficient (xlogp) 1.9
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 1
Hydrogen Bond Acceptor Count (hbondacc) 5
Chemical Identifiers
Formula
C21H24N4O2
IUPAC Name
9-(1-anilinoethyl)-7-methyl-2-morpholin-4-ylpyrido[1,2-a]pyrimidin-4-one
Canonical SMILES
CC1=CN2C(=O)C=C(N=C2C(=C1)C(C)NC3=CC=CC=C3)N4CCOCC4
InChI
InChI=1S/C21H24N4O2/c1-15-12-18(16(2)22-17-6-4-3-5-7-17)21-23-19(13-20(26)25(21)14-15)24-8-10-27-11-9-24/h3-7,12-14,16,22H,8-11H2,1-2H3
InChIKey
CPRAGQJXBLMUEL-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
9907093
ChEBI ID
CHEBI:91428
CAS Number
663619-89-4
TTD ID
D06DNH

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PI3-kinase beta (PIK3CB) TTTHBCA PK3CB_HUMAN Inhibitor [1]
PI3-kinase gamma (PIK3CG) TTHBTOP PK3CG_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Forkhead box protein O3 (FOXO3) OTHXQG4P FOXO3_HUMAN Protein Interaction/Cellular Processes [2]
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN) OTOWDUNT PTEN_HUMAN Drug Response [3]
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PIK3CB) OTO8JQJA PK3CB_HUMAN Drug Response [3]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Post-Translational Modifications [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Discovery agent
ICD Disease Classification N.A.
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
PI3-kinase gamma (PIK3CG) DTT PIK3CG 1.98E-01 -0.05 -0.55
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 209 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MEC1 CTRP2 4.8139 7.4709 4.1561 10.6833
JK1 CTRP2 5.0966 7.9813 4.2053 9.7774
JM1 GDSC1; CTRP2 5.7038 8.0461 4.7472 6.1476
SU-DHL-6 GDSC1; CTRP2 0.4277 4.4772 0.2605 37.9139
OCI-Ly10 CTRP2 1.1028 9.4388 -0.5444 37.2804
Ri-1 CTRP2 1.161 8.4804 -0.1036 36.1066
HuT 78 CTRP2 1.9213 44.4812 -16.7096 45.6993
Karpas-422 GDSC1; CTRP2 2.148 8.6731 0.8686 30.2123
Pfeiffer CTRP2 2.2225 6.0131 1.882 26.6345
NK-92MI GDSC1 2.6772 9.0324 -0.0869 26.5776
MV4-11 GDSC1; CTRP2 2.7541 5.4959 2.5871 22.4945
NU-DUL-1 GDSC1; CTRP2 2.7564 6.0966 2.4418 23.0027
EoL-1 GDSC1; CTRP2 3.134 4.6883 3.1113 19.4655
HH [Human lymphoma] GDSC1; CTRP2 3.1491 10.9762 0.8866 27.2241
SU-DHL-4 GDSC1; CTRP2 3.234 7.8566 2.345 21.9528
Karpas-231 GDSC1 3.3079 6.7484 1.597 13.5357
NCI-H929 CTRP2 3.3687 5.7067 3.2092 18.377
QIMR-WIL GDSC1 3.3711 8.7723 0.6377 19.8511
Daudi GDSC1; CTRP2 3.5427 6.7755 3.0846 18.3092
RCH-ACV CTRP2 3.5935 8.1408 2.6054 19.9772
MOLM-16 CTRP2 3.7049 8.4576 2.5851 19.7524
BL-70 CTRP2 3.7246 5.4636 3.6444 15.7287
MLMA GDSC1 3.7771 8.1303 1.2858 14.1392
KMS-34 CTRP2 3.8134 5.478 3.7377 15.1217
SU-DHL-10 CTRP2 3.8251 6.0633 3.6173 15.5127
SU-DHL-16 GDSC1 3.9914 6.0629 2.4613 4.7105
HT GDSC1; CTRP2 3.9937 7.7503 3.1872 16.6565
Mono-Mac-1 CTRP2 3.9995 8.4615 2.8857 17.8133
MOLM-13 GDSC1; CTRP2 4.0088 5.9665 3.8437 14.1368
WSU-DLCL2 GDSC1; CTRP2 4.0093 6.0011 3.8351 14.1663
DoHH2 GDSC1 4.1023 6.207 2.4664 4.3879
NKM-1 GDSC1 4.1044 8.6849 1.2614 13.2449
GR-ST GDSC1 4.1152 6.5065 2.3323 5.352
BC-3 GDSC1 4.1164 7.5583 1.8238 9.1585
LC4-1 GDSC1 4.1717 11.2966 0.0188 20.5683
Ramos.2G6.4C10 GDSC1 4.1776 7.7836 1.7578 9.4678
PL-21 GDSC1 4.2088 7.4566 1.939 8.0378
Ki-JK CTRP2 4.2243 6.7553 3.8269 13.5628
697 GDSC1; CTRP2 4.2638 6.9933 3.7793 13.6327
PL21 CTRP2 4.2962 8.417 3.2069 15.7842
NALM-6 GDSC1; CTRP2 4.3089 10.6839 2.1567 19.8332
SUP-T11 CTRP2 4.3347 7.529 3.636 13.9934
HAL-01 GDSC1 4.3366 11.5696 0.0102 20.0884
MY-M12 GDSC1 4.337 7.066 2.2132 5.6678
EB1 CTRP2 4.3621 8.0935 3.4189 14.7759
RS4;11 GDSC1; CTRP2 4.405 9.2883 2.9133 16.6732
SU-DHL-8 GDSC1; CTRP2 4.4072 7.5298 3.7111 13.5066
MC116 GDSC1; CTRP2 4.4078 6.2356 4.2026 11.6287
Hs 445 GDSC1 4.4574 7.5886 2.0445 6.5988
KMS-21-BM CTRP2 4.4761 6.2151 4.2834 11.1289
Farage GDSC1 4.4762 7.9248 1.8968 7.6249
Sc-1 GDSC1 4.5122 6.5048 2.5789 2.701
GDM-1 GDSC1; CTRP2 4.521 7.4836 3.8489 12.6639
YT GDSC1 4.5252 6.3872 2.6378 2.2933
KG-1 GDSC1 4.5282 6.961 2.3823 4.0102
M-07e CTRP2 4.5299 11.4787 1.9809 19.9539
BALL-1 GDSC1 4.5724 6.8881 2.4417 3.5079
Karpas-45 GDSC1 4.5765 10.0327 0.946 13.9161
Kasumi-1 GDSC1; CTRP2 4.5951 6.7401 4.2302 10.9839
Kasumi-2 CTRP2 4.5962 9.804 2.854 16.4432
MHH-PREB-1 GDSC1 4.6213 10.0282 0.9803 13.565
RPMI-8402 GDSC1; CTRP2 4.6796 6.998 4.2181 10.7963
KMS-11 CTRP2 4.729 8.3716 3.661 12.8814
MOLT-16 GDSC1; CTRP2 4.7474 6.6749 4.4179 9.841
KE-97 CTRP2 4.7553 9.2536 3.2703 14.3962
GA-10 GDSC1; CTRP2 4.7665 7.8929 3.9186 11.7522
ATN-1 GDSC1 4.7783 18.8564 -3.2675 30.4413
KMS-26 CTRP2 4.7837 7.2165 4.2356 10.4485
CESS GDSC1 4.7884 6.7801 2.6079 2.0495
Jurkat CTRP2 4.7921 6.4458 4.5503 9.2129
Karpas-299 GDSC1; CTRP2 4.802 6.7495 4.4471 9.5767
ALL-PO GDSC1 4.8036 11.4252 0.429 16.391
HC-1 GDSC1 4.8129 12.6594 -0.17 19.5635
THP-1 GDSC1; CTRP2 4.8141 7.6667 4.069 11.0296
ALL-SIL GDSC1 4.8769 6.7002 2.6854 1.4815
MHH-CALL-3 CTRP2 4.9105 9.6287 3.2375 14.164
Mino CTRP2 4.9133 7.3086 4.3293 9.7386
KMS-20 CTRP2 4.9468 7.1089 4.4508 9.1705
LP-1 GDSC1; CTRP2 4.9475 6.5486 4.6799 8.2805
Mono-Mac-6 GDSC1 4.9491 11.5973 0.4494 15.859
DND-41 GDSC1; CTRP2 4.9597 7.545 4.271 9.8515
P32/ISH GDSC1 4.965 6.2211 2.9098 0.3925
P30/OHK GDSC1 4.9723 8.2317 2.068 5.2425
EHEB CTRP2 4.9871 10.8433 2.7154 16.0826
ST486 GDSC1; CTRP2 4.9905 6.4032 4.7795 7.7814
VAL GDSC1 4.9975 8.7749 1.8332 6.8026
BV-173 GDSC1; CTRP2 5.0223 9.6923 3.3116 13.6053
NU-DHL-1 CTRP2 5.0264 9.5535 3.383 13.3045
L-428 GDSC1; CTRP2 5.0292 7.2875 4.4571 8.9311
KM-H2 GDSC1; CTRP2 5.0559 8.7019 3.8229 11.4362
U-937 CTRP2 5.0563 6.9668 4.6252 8.1951
Hs 611.T CTRP2 5.0666 7.9439 4.1935 9.8982
ME1 GDSC1 5.0833 6.4794 2.8619 0.4818
A4/Fukuda GDSC1; CTRP2 5.0907 6.7102 4.7684 7.5437
JVM-3 GDSC1; CTRP2 5.096 9.6505 2.7842 10.0555
SCC-3 GDSC1 5.1422 6.7419 2.788 0.7178
IM-9 GDSC1 5.1485 6.4348 2.9034 0.3162
BC-1 GDSC1 5.149 9.116 1.7689 6.9003
RPMI-6666 GDSC1; CTRP2 5.1754 8.3647 4.0991 10.024
SUP-M2 GDSC1; CTRP2 5.1814 6.3558 5.0024 6.3955
TUR GDSC1 5.1952 6.9129 2.7452 0.8517
OCI-AML-3 GDSC1; CTRP2 5.2179 6.5556 4.9651 6.4351
NOMO-1 GDSC1; CTRP2 5.2546 9.1014 3.8164 11.0061
Peer CTRP2 5.2571 7.0315 4.8032 6.9668
PF-382 GDSC1; CTRP2 5.2632 7.9899 4.3629 8.7356
ROS-50 GDSC1 5.2707 8.0779 2.3044 3.1371
KMS-12-BM GDSC1; CTRP2 5.2768 7.2838 4.7084 7.2969
H9 GDSC1 5.2839 12.0242 0.4775 14.7823
SUP-HD1 GDSC1; CTRP2 5.2959 7.1373 4.7946 6.9027
MM1.S CTRP2 5.3062 7.4623 4.6546 7.4426
MOLT-13 CTRP2 5.3069 7.4424 4.6646 7.3998
KCL-22 GDSC1; CTRP2 5.3166 7.0486 4.8557 6.6054
RPMI-8226 GDSC1; CTRP2 5.3168 7.325 4.7292 7.114
KY821 GDSC1 5.3229 6.9521 2.7834 0.6036
CML-T1 CTRP2 5.3305 7.205 4.7982 6.8014
SET-2 CTRP2 5.3368 7.299 4.761 6.9358
RPMI-8866 GDSC1 5.3608 6.9525 2.7984 0.5271
OCI-AML-2 GDSC1; CTRP2 5.3662 7.2466 4.8145 6.6473
MOLP-8 GDSC1; CTRP2 5.3754 6.6628 5.0861 5.5382
KMM-1 CTRP2 5.3862 9.9049 3.5415 11.8511
MOLT-3 CTRP2 5.3903 6.5904 5.1323 5.3178
Jiyoye GDSC1 5.3955 7.4813 2.612 1.2653
WIL2 NS GDSC1 5.4021 6.9308 2.8224 0.4268
L-540 GDSC1; CTRP2 5.4096 7.3088 4.8281 6.4862
JURL-MK1 GDSC1; CTRP2 5.4281 6.6846 5.1312 5.2217
SUP-T1 GDSC1; CTRP2 5.4375 7.2989 4.8601 6.2881
KHM-1B CTRP2 5.4436 9.1351 3.3215 6.9697
CA46 GDSC1; CTRP2 5.4506 6.874 5.0699 5.4075
RC-K8 GDSC1 5.4877 6.9929 2.8327 0.3553
OPM-2 GDSC1; CTRP2 5.4954 6.4856 5.286 4.4355
SEM CTRP2 5.4967 7.3168 4.9092 5.9459
BE-13 GDSC1 5.5123 7.2966 2.7321 0.6619
REC-1 CTRP2 5.5172 9.0675 4.0737 9.3592
L-363 GDSC1; CTRP2 5.5242 6.85 5.1548 4.8817
BL-41 GDSC1; CTRP2 5.545 12.8988 2.1926 16.8906
EB2 GDSC1 5.5465 13.1243 0.1279 16.0146
MOLT-4 GDSC1 5.5589 7.2751 2.7586 0.5417
P3HR-1 CTRP2 5.568 11.9561 2.6828 14.9471
Ku812 GDSC1; CTRP2 5.5709 8.1723 4.564 7.2014
SU-DHL-1 GDSC1; CTRP2 5.5874 7.1316 5.0851 5.0106
TALL-1 [Human adult T-ALL] CTRP2 5.5903 8.9201 4.2126 8.6229
HDLM-2 GDSC1; CTRP2 5.5907 8.6584 4.3424 8.0805
SKM-1 GDSC1; CTRP2 5.5979 6.8593 5.2238 4.4205
F-36P CTRP2 5.5989 7.5033 4.9171 5.6747
Loucy GDSC1 5.6187 7.2294 2.798 0.3909
SR GDSC1; CTRP2 5.6302 8.1449 4.6317 6.789
P12-Ichikawa CTRP2 5.6305 7.2611 5.0642 4.9954
KMS-18 CTRP2 5.6325 7.7812 4.8127 6.0312
JeKo-1 CTRP2 5.6357 8.3764 4.5225 7.2323
TK [Human B-cell lymphoma] GDSC1 5.6369 7.1026 2.8493 0.2554
L-1236 GDSC1; CTRP2 5.6407 9.9784 3.7316 10.5215
OCI-Ly3 CTRP2 5.6426 7.7289 4.8477 5.8634
LAMA-84 GDSC1; CTRP2 5.6526 7.7114 4.8654 5.7677
U-698-M GDSC1 5.6669 8.304 2.4078 1.9857
CMK CTRP2 5.7059 6.4408 5.5231 2.9462
OCI-Ly19 GDSC1; CTRP2 5.7159 8.3589 4.6032 6.7231
EM-2 GDSC1; CTRP2 5.7198 7.4487 5.0562 4.8258
Namalwa GDSC1; CTRP2 5.7292 7.2011 5.1862 4.2658
SUP-B15 GDSC1; CTRP2 5.7432 8.5911 4.5121 7.0468
JVM-2 GDSC1 5.7556 14.5984 -0.4395 18.2947
RL GDSC1; CTRP2 5.7585 6.6751 5.4677 3.0388
Granta-519 GDSC1; CTRP2 5.7742 9.5398 4.0667 8.8474
DB GDSC1; CTRP2 5.8066 6.8706 5.4195 3.1246
KMOE-2 GDSC1 5.8095 7.9102 2.6244 0.8545
KE-37 GDSC1; CTRP2 5.8416 6.8459 5.4642 2.8608
EJM GDSC1; CTRP2 5.8488 7.7742 5.0115 4.7343
HEL GDSC1; CTRP2 5.8843 8.4889 4.6863 6.0252
CCRF-CEM GDSC1 5.9175 7.4897 2.8165 0.2346
Ci-1 CTRP2 5.9471 6.7766 5.5944 2.0881
K-562 GDSC1; CTRP2 5.9528 6.982 5.4972 2.4833
KYO-1 CTRP2 5.9826 7.3237 5.3526 3.0294
SK-MM-2 GDSC1; CTRP2 5.9838 7.0147 5.5079 2.3747
MN-60 GDSC1 6.0029 7.7783 2.7474 0.3594
HD-MY-Z CTRP2 6.0119 7.3065 5.3861 2.8306
DG-75 GDSC1 6.0224 7.9093 2.7084 0.4526
HL-60 GDSC1; CTRP2 6.0351 8.7901 4.6638 5.8213
HuNS1 CTRP2 6.0361 13.7395 2.1899 15.8961
NB4 GDSC1; CTRP2 6.0608 11.1334 3.5136 10.5833
MOTN-1 CTRP2 6.0634 7.9618 5.1014 3.927
ARH-77 GDSC1 6.0819 17.4437 -1.5919 22.2249
VL51 GDSC1 6.1147 8.0496 2.6932 0.4523
P31/FUJ GDSC1; CTRP2 6.117 7.9539 5.1495 3.6238
HEL 92.1.7 CTRP2 6.1259 8.2719 4.9979 4.244
DEL GDSC1; CTRP2 6.1279 7.1166 5.5762 1.8129
KO52 CTRP2 6.1478 7.3892 5.4561 2.2804
AML-193 CTRP2 6.1537 7.6425 5.3345 2.7795
JJN-3 GDSC1; CTRP2 6.1557 8.2492 5.0333 4.0397
TF-1 CTRP2 6.1581 7.1681 5.5742 1.7676
CTB-1 GDSC1 6.1684 13.6724 0.2832 13.6579
Karpas-620 CTRP2 6.1984 7.8348 5.2741 2.9525
SIG-M5 GDSC1; CTRP2 6.2097 7.1492 5.623 1.4766
MEG-01 GDSC1 6.2639 8.2956 2.662 0.4701
WSU-NHL GDSC1 6.3224 15.255 -0.3673 16.5686
OCI-M1 GDSC1; CTRP2 6.3291 7.4025 5.5855 1.4438
MOLM-6 CTRP2 6.334 8.9922 4.8043 4.6796
KMS-27 CTRP2 6.3696 9.5638 4.5478 5.6903
U266B1 GDSC1; CTRP2 6.3779 9.9162 4.3789 6.3821
HPB-ALL CTRP2 6.3862 8.5255 5.0759 3.4571
ML-2 GDSC1 6.4642 16.1703 -0.7098 17.793
CTV-1 GDSC1 6.4798 14.9329 -0.1098 14.9624
AMO1 GDSC1; CTRP2 6.4838 7.8202 5.4906 1.6039
A3/Kawakami GDSC1; CTRP2 6.6087 7.6955 5.6282 0.9139
MHH-CALL-4 CTRP2 6.9137 21.9712 -1.2067 24.5507
ME1 CTRP2 6.9462 10.0351 4.7414 3.9613
MOLP-2 CTRP2 7.2337 12.3071 3.8404 7.1919
Toledo CTRP2 7.5401 9.2868 5.435 0.751
Raji GDSC1; CTRP2 7.5771 9.7721 5.2497 1.2995
Reh GDSC1; CTRP2 7.6486 11.8939 4.3242 4.6548
OCI-AML-5 GDSC1; CTRP2 7.6557 12.6183 3.984 5.9904
⏷ Show the Full List of 209 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE15 CTRP2 5.8377 9.5273 4.1278 8.4623
TE8 CTRP2 6.2336 11.076 3.6845 9.5456
TE-8 GDSC1 4.7521 6.9098 2.533 2.5711
TE-6 GDSC1 4.9014 7.3457 2.4239 3.0082
KYSE-70 CTRP2 5.3808 8.6783 4.1404 9.3827
TE-15 GDSC1 5.3939 7.6151 2.5581 1.5301
OE33 CTRP2 5.4982 9.0185 4.0807 9.3713
TE-5 GDSC1; CTRP2 5.6792 7.2631 5.1092 4.6978
OE21 CTRP2 5.7211 6.9539 5.2984 3.8212
TE-10 GDSC1; CTRP2 5.7881 8.6922 4.5013 6.9983
KYSE-520 CTRP2 5.9122 8.1836 4.8627 5.2281
TE-11 CTRP2 5.9254 6.7656 5.5804 2.1931
KYSE-410 CTRP2 5.9982 10.5281 3.7639 9.6654
KYSE-140 CTRP2 6.1694 10.4093 3.9652 8.4964
TE-9 GDSC1; CTRP2 6.237 7.6511 5.3954 2.3783
TE-14 CTRP2 6.2671 9.5116 4.4927 6.1045
OE19 CTRP2 6.356 7.5587 5.5286 1.6353
KYSE-30 CTRP2 6.4406 9.0946 4.8356 4.3658
KYSE-180 CTRP2 6.7396 9.1803 5.0112 3.1704
KYSE-450 CTRP2 6.7896 8.5174 5.36 1.7162
COLO 680N CTRP2 6.8293 11.9334 3.7256 8.3155
TE-1 GDSC1; CTRP2 6.9797 13.027 3.2986 9.8016
KYSE-150 CTRP2 7.1668 9.5399 5.1199 2.1791
KYSE-510 CTRP2 7.1923 11.6713 4.1207 6.1161
EC-GI-10 GDSC1; CTRP2 8.1229 10.0239 5.4064 0.4993
TE-4 CTRP2 9.1932 27.7231 -2.2958 23.2569
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 6.4872 8.3282 5.2472 2.5869
MZ-PC-1 GDSC1 5.2813 10.6878 1.116 10.917
PK-59 CTRP2 5.4562 9.3219 3.8929 10.2436
SNU-213 CTRP2 5.4708 14.4504 1.3543 20.0654
BxPC-3 CTRP2 5.698 10.6862 3.4289 11.6576
DAN-G CTRP2 5.9227 6.9977 5.4629 2.6897
Panc 08.13 CTRP2 5.9355 9.7719 4.0891 8.4292
PSN1 GDSC1; CTRP2 5.993 8.1212 4.9629 4.6461
TCC-Pan2 CTRP2 6.0778 11.5558 3.3165 11.3622
MIA PaCa-2 CTRP2 6.1108 7.3477 5.4472 2.3848
AsPC-1 CTRP2 6.157 8.3746 4.9717 4.2963
KP-4 CTRP2 6.2597 9.2424 4.6211 5.5799
Panc 03.27 CTRP2 6.2599 8.5597 4.9615 4.1525
Panc 04.03 CTRP2 6.3038 8.2133 5.1678 3.2131
KP-2 CTRP2 6.3479 7.5812 5.5119 1.716
PK-45H CTRP2 6.3601 11.5821 3.534 9.9333
SW1990 CTRP2 6.4114 9.1523 4.7847 4.6273
HPAF-II CTRP2 6.4285 12.6775 2.3109 9.6358
KP-3 CTRP2 6.4725 12.9293 2.9519 12.0937
HuP-T4 CTRP2 6.4965 12.1976 3.336 10.4969
L3.3 CTRP2 6.5066 9.3456 4.7614 4.564
HuP-T3 CTRP2 6.6524 8.4552 5.3003 2.1306
Capan-1 CTRP2 6.6891 9.9609 4.5941 4.9588
Panc 02.03 CTRP2 6.7009 8.6478 5.2408 2.3009
PaTu 8988t CTRP2 6.735 8.1338 5.5037 1.2349
PaTu 8988s CTRP2 6.8141 8.5808 5.3458 1.7407
QGP-1 CTRP2 6.8176 8.341 5.4586 1.3096
PaTu 8902 CTRP2 6.8302 8.1843 5.5367 1.0115
YAPC CTRP2 6.9835 10.2882 4.645 4.2975
SUIT-2 CTRP2 7.1855 10.7769 4.5483 4.3967
SU.86.86 CTRP2 7.3288 28.4553 -4.1095 29.4647
Hs 766T CTRP2 7.399 21.0512 -0.3622 21.5552
HPAC CTRP2 7.6313 11.3025 4.5908 3.6398
Panc 05.04 CTRP2 8.5887 28.9289 -3.3527 26.2275
CFPAC-1 CTRP2 9.4286 19.1207 2.066 10.7573
SNU-410 CTRP2 10.8199 30.7255 -2.5781 21.5605
Capan-2 CTRP2 10.9007 22.8179 1.277 11.4602
Panc 10.05 CTRP2 11.3956 34.4803 -3.9981 23.5211
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 61 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 5.8904 6.9701 5.4477 2.8223
IST-MEL1 GDSC1 1.8808 15.7655 -4.1382 40.3214
GAK GDSC1 3.6358 7.7876 1.345 14.2029
WM115 CTRP2 3.7144 15.8338 -0.9059 30.5315
SH-4 GDSC1 4.0645 6.3724 2.3624 5.2602
A-388 GDSC1 4.6059 6.6953 2.5469 2.7388
MZ-MEL-7 GDSC1 4.8357 21.7049 -4.6404 33.1152
Hs 852.T CTRP2 4.9512 8.2227 3.9494 11.1702
COLO 792 CTRP2 5.127 9.359 3.5718 12.3022
CP66-MEL GDSC1 5.1296 7.2063 2.5995 1.627
LB2518-MEL GDSC1 5.2149 11.3728 0.7439 13.4007
Mel Ho CTRP2 5.6663 15.1106 1.1925 20.1996
WM88 CTRP2 5.68 15.5948 0.9622 20.9275
RPMI-7951 CTRP2 5.7062 9.9461 3.805 10.0802
LB373-MEL-D GDSC1 5.8864 13.2063 0.3189 14.1367
CJM [Human melanoma] CTRP2 6.1167 7.0987 5.5762 1.8327
G-361 CTRP2 6.1818 10.4699 3.9451 8.557
LOX-IMVI GDSC1; CTRP2 6.1938 8.142 5.1174 3.6175
DJM-1 GDSC1 6.2026 12.9477 0.6456 11.5783
HMCB CTRP2 6.2309 7.1379 5.6442 1.3548
IGR-1 CTRP2 6.3062 8.0159 5.2674 2.7942
MeWo CTRP2 6.3644 9.7712 4.4405 6.1485
WM983B CTRP2 6.3918 10.0047 4.3458 6.496
Hs 688(A).T CTRP2 6.4694 21.404 -1.2842 25.5458
A2058 CTRP2 6.4788 8.1707 5.3179 2.3102
Mel JuSo CTRP2 6.4797 11.9349 3.4536 10.0458
SK-MEL-5 CTRP2 6.5586 8.8196 5.0585 3.2508
SK-MEL-3 CTRP2 6.578 16.5004 1.2542 18.1808
Hs 936.T CTRP2 6.6727 9.7308 4.695 4.5685
MZ-MEL-2 GDSC1 6.7451 19.3931 -2.0705 22.3477
SK-MEL-1 GDSC1; CTRP2 6.7714 8.6657 5.2788 2.0555
IPC-298 CTRP2 6.7796 9.549 4.8606 3.7235
Hs 940.T CTRP2 6.7852 14.4628 2.4355 13.5436
Hs 944.T CTRP2 6.8422 14.0776 2.6717 12.5299
SK-MEL-30 CTRP2 6.8443 9.5988 4.8816 3.5426
MMAc-SF GDSC1 6.8453 29.343 -6.8816 32.6086
COLO 829 GDSC1; CTRP2 6.9405 8.9162 5.2688 1.8821
SK-MEL-24 CTRP2 6.9526 9.768 4.8743 3.4168
A-375 CTRP2 6.9711 10.4113 4.5767 4.593
WM266-4 CTRP2 7.0074 19.9501 -0.1231 21.6008
MDA-MB-435S CTRP2 7.0569 11.7444 3.9878 6.8676
SK-MEL-2 GDSC1; CTRP2 7.2428 8.2815 5.6983 0.2403
IGR-39 CTRP2 7.2872 14.5868 2.7596 11.4208
SK-MEL-28 CTRP2 7.2988 8.3404 5.6993 0.2165
IGR-37 CTRP2 7.3269 12.367 3.8776 6.8977
WM793 CTRP2 7.3987 15.3123 2.485 12.2884
WM1799 CTRP2 7.4761 15.5556 2.4229 12.3941
K029AX CTRP2 7.5627 12.96 3.7556 7.0357
WT2-iPS CTRP2 7.5674 8.8202 5.6298 0.2541
COLO 741 CTRP2 7.6377 9.9171 5.2193 1.3475
Hs 895.T CTRP2 7.947 17.5232 1.8031 13.8814
Hs 294T CTRP2 7.9895 16.7346 2.221 12.3119
SK-MEL-31 CTRP2 8.1751 15.3984 3.002 9.095
COLO 800 GDSC1; CTRP2 8.4732 17.5395 2.1736 11.739
HT-144 GDSC1; CTRP2 8.5942 18.3009 1.8891 12.5681
Hs 934.T CTRP2 8.6115 19.3548 1.3884 14.255
RVH-421 CTRP2 8.8939 22.0059 0.2959 17.2424
UACC-257 GDSC1; CTRP2 9.0845 18.2977 2.2287 10.6584
A101D GDSC1; CTRP2 9.3246 15.8892 3.5126 5.686
Hs 839.T CTRP2 12.0058 25.6372 0.6584 12.0048
UACC-62 CTRP2 12.1397 23.6331 1.6607 8.8481
⏷ Show the Full List of 61 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE-12 GDSC1 4.9894 8.9908 1.7274 7.5513
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 5.3842 8.0375 2.3801 2.5111
Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SK-N-DZ GDSC1 4.3694 8.3385 1.6239 9.8908
SJNB-10 GDSC1 4.6229 6.6193 2.5896 2.4324
CHP-212 CTRP2 4.999 5.8603 4.948 7.1399
SK-N-BE(2)-M17 GDSC1 5.0486 6.9379 2.67 1.3539
SJNB-14 GDSC1 5.081 6.8491 2.7202 1.071
Kelly GDSC1; CTRP2 5.3129 7.098 4.8296 6.7195
SJNB-5 GDSC1 5.3445 7.1767 2.7078 0.8833
SJNB-6 GDSC1 5.3788 6.8142 2.8553 0.3431
TGW GDSC1 5.3852 7.2441 2.6993 0.8849
NH-12 GDSC1 5.4554 7.7127 2.5474 1.5159
SK-N-FI GDSC1; CTRP2 5.504 6.8101 5.1527 4.941
LA-N-6 GDSC1 5.5526 7.2159 2.7776 0.4842
NB1 GDSC1; CTRP2 5.571 7.7131 4.7888 6.2688
SK-N-SH CTRP2 5.6785 8.4922 4.5037 7.2187
SJNB-17 GDSC1 5.713 7.8428 2.6098 0.9867
KP-N-YN GDSC1 5.8432 7.8944 2.644 0.7584
NB(TU)1 GDSC1 5.8717 7.3905 2.8342 0.2133
SJNB-13 GDSC1 5.8977 7.5036 2.8047 0.2653
GOTO GDSC1 5.9069 8.9501 2.2587 2.482
NB69 GDSC1 5.9665 7.9454 2.6741 0.582
IMR-5 GDSC1 5.9711 7.4791 2.839 0.1789
NH-6 CTRP2 6.0093 7.3858 5.3442 3.0115
KP-N-SI9s CTRP2 6.0374 9.6071 4.2572 7.5245
SiMa GDSC1; CTRP2 6.0603 8.3746 4.8925 4.811
SK-N-BE(2) CTRP2 6.1349 9.1047 4.589 5.9448
CHP-126 GDSC1; CTRP2 6.1474 8.1747 5.0638 3.9271
SJNB-12 GDSC1 6.1593 8.1482 2.675 0.482
SK-N-AS CTRP2 6.3067 8.0717 5.2402 2.9065
KP-N-YS GDSC1 6.5373 8.5511 2.673 0.338
GI-ME-N GDSC1 6.5891 30.3998 -7.5999 33.9986
MHH-NB-11 GDSC1; CTRP2 6.7462 10.0099 4.6118 4.7948
SJNB-7 GDSC1 6.7606 15.3347 -0.1175 14.3734
⏷ Show the Full List of 32 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-1079 CTRP2 4.3803 7.5231 3.686 13.6763
SNU-478 CTRP2 4.4944 10.6001 2.3739 18.5607
HuH-28 CTRP2 5.352 10.2706 3.3297 12.7968
SNU-308 CTRP2 6.2147 16.6128 0.9014 20.0413
SNU-1196 CTRP2 6.27 8.1375 5.1794 3.2228
SNU-869 CTRP2 6.7147 8.6196 5.2634 2.192
HuCC-T1 CTRP2 6.7686 10.4474 4.4134 5.5773
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NOS-1 [Human HNSCC] GDSC1 3.7055 7.579 1.504 12.8184
EW-12 GDSC1 4.7131 13.2963 -0.5586 21.6974
EW-1 GDSC1 4.9452 7.5574 2.355 3.3743
ES6 GDSC1 4.9522 15.8992 -1.6651 25.3906
SK-PN-DW GDSC1 4.9622 7.7426 2.2826 3.817
ES8 GDSC1 4.9828 8.0076 2.1757 4.4897
EW-24 GDSC1 5.1374 6.3793 2.9189 0.279
EW-18 GDSC1 5.159 9.2023 1.7352 7.107
SaOS-2 CTRP2 5.3356 7.7691 4.5381 7.8467
SK-N-MC CTRP2 5.5486 6.187 5.4587 3.6256
TC71 CTRP2 5.5733 7.1348 5.0699 5.1062
ES4 GDSC1 5.6111 8.5319 2.2868 2.7247
H-EMC-SS GDSC1 5.624 8.1804 2.4377 1.8813
MHH-ES-1 CTRP2 5.6559 8.6418 4.4092 7.6617
SK-ES-1 GDSC1; CTRP2 5.7015 7.5705 4.9797 5.1843
TC-71 GDSC1 5.7584 7.3414 2.8104 0.3009
EW-22 GDSC1 5.7689 7.6673 2.698 0.618
G-292 clone A141B1 CTRP2 5.85 10.5292 3.638 10.4829
EW-13 GDSC1 6.0094 14.4194 -0.1784 16.4104
A-673 CTRP2 6.0528 7.0533 5.547 2.0746
EW-11 GDSC1 6.0633 8.4986 2.5079 1.1203
HOS CTRP2 6.1797 7.271 5.5399 1.8735
MG-63 CTRP2 6.2411 9.5701 4.4427 6.3618
EW-16 GDSC1 6.2727 8.9863 2.4105 1.3523
CAL-78 CTRP2 6.3191 14.6676 1.9595 16.198
ES5 GDSC1 6.3438 8.963 2.4494 1.135
EW-3 GDSC1 6.5329 8.893 2.5507 0.6587
Hs 822.T CTRP2 6.5529 7.4288 5.716 0.6542
U2OS CTRP2 6.6487 8.6464 3.4305 0.4044
ES7 GDSC1 6.9485 19.147 -1.8102 21.0134
Hs 888.T CTRP2 7.3848 11.344 4.4113 4.6663
SJSA-1 GDSC1; CTRP2 7.8085 19.69 0.6302 17.9876
ES1 GDSC1 7.8339 25.2298 -4.1376 25.8331
SW1353 CTRP2 8.6982 21.0954 0.5997 16.6374
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 78 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1599 GDSC1 2.1599 14.0707 -3.0491 37.72
Evsa-T GDSC1 2.8248 8.6698 0.2232 24.3761
ZR-75-1 CTRP2 3.754 13.3191 0.3579 27.2036
HCC2157 GDSC1 3.8379 6.9056 1.9398 9.1294
MRK-nu-1 GDSC1 4.1354 6.9782 2.1193 6.8944
OCUB-M GDSC1 4.145 8.6125 1.3274 12.66
MCF-7 CTRP2 4.3184 8.4085 2.7247 12.0407
HCC1395 CTRP2 5.2993 12.446 2.2033 17.3757
SK-BR-3 CTRP2 5.3461 8.0821 4.3979 8.3977
MDA-MB-361 CTRP2 5.3488 9.136 3.8865 10.5059
HCC1954 CTRP2 5.3621 7.6127 4.0144 4.0214
HCC1143 CTRP2 5.3776 8.9751 3.992 10.0047
CAL-51 CTRP2 5.5 7.8906 4.6359 7.062
EFM-192A CTRP2 5.5035 7.1683 4.9861 5.6159
HCC38 CTRP2 5.7067 12.1499 2.7058 14.5683
UACC-812 GDSC1 5.7096 7.4031 2.7705 0.4255
MDA-MB-468 CTRP2 5.7136 11.231 3.1705 12.6856
Hs 578T CTRP2 5.7882 7.0573 5.3113 3.6144
COLO 824 GDSC1 5.7912 8.0923 2.5476 1.1832
ZR-75-30 CTRP2 5.7944 7.0477 5.3217 3.5573
CAMA-1 CTRP2 5.7988 11.3402 2.501 9.9342
DU4475 GDSC1; CTRP2 5.8051 7.0508 5.3301 3.4989
HCC1419 CTRP2 5.9328 8.8819 4.5316 6.5774
MDA-MB-453 CTRP2 5.9724 8.0074 5.0023 4.5214
HMC-1-8 CTRP2 5.9992 8.1352 4.9611 4.6416
HCC1500 GDSC1; CTRP2 6.0026 7.1338 5.4644 2.5197
HCC202 CTRP2 6.0296 8.6724 4.7181 5.6035
MFM-223 GDSC1 6.0316 7.7256 2.7761 0.2826
BT-474 GDSC1; CTRP2 6.0506 8.0082 5.0677 4.0934
HCC1806 CTRP2 6.1238 8.087 4.3007 1.6672
BT-20 CTRP2 6.2076 7.6155 5.3904 2.4499
HCC1428 CTRP2 6.2154 7.7438 5.3327 2.6774
CAL-148 GDSC1; CTRP2 6.2282 8.7516 4.8408 4.7154
HCC2218 GDSC1; CTRP2 6.2752 9.1627 4.6732 5.3334
CAL-85-1 CTRP2 6.3774 8.3432 5.1594 3.1246
KPL-1 CTRP2 6.3951 19.2375 -0.2622 23.1246
T-47D CTRP2 6.6752 11.1019 4.0202 7.3604
HCC1187 GDSC1 6.8573 15.4927 -0.1298 14.2234
BT-549 CTRP2 6.9375 17.0409 1.2716 17.4538
MDA-MB-231 CTRP2 6.9485 14.3922 2.5979 12.6281
HDQ-P1 CTRP2 7.1062 10.6998 4.5312 4.5794
HCC1937 CTRP2 7.3344 14.5905 2.793 11.2124
JIMT-1 CTRP2 7.3581 9.039 5.4484 0.8416
CAL-120 CTRP2 7.7708 9.231 5.5595 0.3178
BT 231 CTRP2 5.0594 11.5954 2.4106 17.1112
BT 239 CTRP2 5.151 8.2451 4.133 9.9427
BT 416 CTRP2 5.9683 8.4097 4.7978 5.3887
BT 145 CTRP2 6.0253 8.959 4.5712 6.2294
BT164 CTRP2 6.2216 8.4833 4.9693 4.1886
BT 428 CTRP2 6.4235 8.1091 5.3084 2.4343
BT 224 CTRP2 6.5579 8.4026 5.261 2.424
BT 245 CTRP2 6.5703 9.2397 4.861 4.0467
BT 112 CTRP2 6.6613 10.0928 4.5085 5.3583
BT 172 CTRP2 6.7167 8.37 5.3828 1.7196
BT 504 CTRP2 6.7214 8.2484 5.4425 1.483
BT 422 CTRP2 6.7366 9.4881 4.8598 3.7916
BT 330 CTRP2 6.743 8.9026 5.1473 2.6167
BT 359 CTRP2 6.8745 9.5922 4.9055 3.4023
BT 444 CTRP2 6.9422 8.9562 5.2513 1.9469
BT 271 CTRP2 6.9483 11.1714 4.1896 6.2121
BT 482 CTRP2 6.969 8.4432 5.4997 1.0048
BT 286 CTRP2 7.0013 8.7057 5.4012 1.321
BT 216 CTRP2 7.0477 8.6665 5.445 1.1194
BT 333 CTRP2 7.0726 8.3842 5.5796 0.6536
BT 340 CTRP2 7.1183 8.4684 5.5672 0.6572
BT 320 CTRP2 7.1619 8.1334 5.7206 0.2263
BT147 CTRP2 7.1795 9.0992 5.3271 1.4038
BT 440 CTRP2 7.2406 13.269 3.374 9.0665
BT 179 CTRP2 7.3022 12.7086 3.6935 7.6803
BT 498 CTRP2 7.6437 8.6118 5.7332 0.0768
BT 248 CTRP2 7.8575 10.1884 5.2172 1.1758
BT 139 CTRP2 8.0647 16.4608 2.4088 11.502
BT 328 CTRP2 8.1108 12.6451 4.266 4.2983
BT 187 CTRP2 8.3216 14.0373 3.749 6.0142
BT 232 CTRP2 8.7658 18.2379 2.0396 11.7837
BT 228 CTRP2 8.8066 17.814 2.2721 10.8955
BT 159 CTRP2 9.1724 16.9335 2.9337 7.9887
BT 131 CTRP2 9.908 22.6121 0.7174 14.4962
⏷ Show the Full List of 78 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 5.8266 8.9095 4.4265 7.2329
Cancer Drug Sensitivity Data Curated from 58 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-336MG GDSC1 -0.0205 28.4284 -12.1151 48.7406
D-542MG GDSC1 0.1953 48.3686 -21.8573 49.0071
D-247MG GDSC1 3.2229 24.8934 -7.5465 40.3655
D-392MG GDSC1 3.5612 11.3987 -0.5188 25.215
Onda 10 GDSC1 4.2416 33.482 -10.9988 40.9278
KINGS-1 GDSC1 4.6251 17.8511 -2.8873 29.908
KS-1 [Human Krukenberg tumour] GDSC1 4.8178 18.4436 -3.0313 29.7673
AM-38 GDSC1 5.0227 7.1385 2.5755 1.8994
CAS-1 GDSC1; CTRP2 5.0776 19.6969 -1.6034 28.9931
D283 Med GDSC1; CTRP2 5.2137 6.5399 4.9669 6.4398
Onda 11 GDSC1 5.4826 21.3777 -3.9746 30.3292
D-502MG GDSC1 5.5088 12.1573 0.5671 13.6835
Hs 683 CTRP2 5.5849 10.4679 3.4389 11.851
SF539 GDSC1; CTRP2 5.648 9.3616 4.0449 9.2003
T98G CTRP2 5.741 8.7736 4.4194 7.4394
SNU-466 CTRP2 5.7749 11.3609 3.1584 12.61
LN-18 CTRP2 5.7755 9.2778 4.1985 8.293
M059K CTRP2 5.8497 9.4427 4.1804 8.218
D-263MG GDSC1 5.949 19.0947 -2.4966 25.5115
SW1783 CTRP2 6.0458 9.2578 4.4389 6.7456
SW1088 CTRP2 6.0482 15.566 1.2868 19.1027
YH-13 CTRP2 6.0907 11.2147 3.4977 10.5912
42-MG-BA CTRP2 6.1598 11.2546 3.5348 10.3052
GaMG CTRP2 6.2541 13.142 2.6688 13.6271
U-118MG CTRP2 6.4294 10.113 4.3214 6.5316
SNU-626 CTRP2 6.4557 8.0898 5.3409 2.2512
SNB-75 GDSC1; CTRP2 6.4954 19.4152 -0.269 22.9518
Becker GDSC1; CTRP2 6.5434 10.8134 4.0619 7.4139
ONS-76 GDSC1; CTRP2 6.5877 11.9487 3.5319 9.5303
8-MG-BA GDSC1; CTRP2 6.5895 8.2449 5.3586 1.9848
SNU-738 CTRP2 6.61 8.4615 5.2686 2.3176
YKG-1 CTRP2 6.7695 10.9608 4.1612 6.6182
A-172 CTRP2 6.7713 9.7889 4.7379 4.2372
SNU-1105 CTRP2 6.7833 16.2475 0.8178 14.9425
GI-1 GDSC1 6.8081 26.9796 -5.7422 30.9295
SF295 CTRP2 6.9189 13.1761 3.1786 10.3885
DK-MG CTRP2 6.9464 13.9227 2.8294 11.7296
KNS-60 CTRP2 7.0622 24.2267 -2.2131 26.5019
LN-229 CTRP2 7.0752 10.7767 4.4725 4.8623
SNU-489 CTRP2 7.1771 11.0054 4.4326 4.8745
KNS-81-FD GDSC1 7.1884 22.629 -3.3298 25.1106
KNS-42 GDSC1; CTRP2 7.1927 10.3245 4.769 3.5073
Daoy CTRP2 7.2995 14.8535 2.6371 11.8735
TM-31 CTRP2 7.3002 10.8884 4.5721 4.1425
SNU-201 CTRP2 7.3128 13.1697 3.4756 8.5425
NMC-G1 GDSC1; CTRP2 7.5425 9.4434 5.3714 0.9393
GB-1 GDSC1; CTRP2 7.6987 14.7069 3.0025 9.8109
CCF-STTG1 CTRP2 8.04 14.2126 3.4799 7.4381
SF126 GDSC1; CTRP2 8.1255 15.9091 2.7204 10.2413
U-87MG ATCC GDSC1; CTRP2 8.2567 16.3581 2.5947 10.5173
KALS-1 GDSC1; CTRP2 8.3053 23.3499 -0.804 21.1846
SF268 GDSC1; CTRP2 8.3081 19.2894 1.2007 15.3511
GOS-3 CTRP2 8.4826 15.8251 3.0065 8.6395
GMS-10 CTRP2 9.3218 17.617 2.7083 8.6176
KNS-81 CTRP2 10.8341 36.7726 -5.5336 26.6915
U-251MG CTRP2 11.4345 27.5004 -0.5921 16.1432
DBTRG-05MG CTRP2 11.4982 25.0623 0.6056 12.7608
KG-1-C CTRP2 11.8175 25.0914 0.7944 11.8263
⏷ Show the Full List of 58 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ETK-1 GDSC1 4.0365 6.2361 2.4087 4.9865
TGBC1TKB GDSC1 4.4728 8.6917 1.5252 10.302
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHUEM-7 CTRP2 4.3612 6.5648 4.043 12.3572
JHUEM-2 CTRP2 4.5724 7.046 4.0856 11.6021
AN3-CA CTRP2 5.3174 7.1893 4.7924 6.8574
HEC-59 CTRP2 5.5014 8.632 4.2742 8.5593
HEC-1-A CTRP2 5.5637 9.09 4.1045 9.1307
JHUEM-1 CTRP2 5.6764 6.6213 5.4119 3.4663
JHUEM-3 CTRP2 5.8401 8.0814 4.851 5.4249
ESS-1 CTRP2 5.9373 7.7867 5.0824 4.255
HEC-151 CTRP2 6.0046 7.4151 5.3256 3.0992
EN CTRP2 6.2095 7.2648 5.5658 1.7148
MFE-319 CTRP2 6.211 7.5563 5.4224 2.3103
MFE-296 CTRP2 6.2299 11.2265 3.6062 9.8771
HEC-6 CTRP2 6.3138 8.1808 5.1916 3.0973
RL95-2 GDSC1; CTRP2 6.3163 10.6434 3.9674 8.214
HEC-251 CTRP2 6.5343 9.261 4.8239 4.2585
HEC-50B CTRP2 6.5475 11.9299 3.5097 9.6932
HEC-1-B CTRP2 6.5629 10.004 4.4784 5.6465
HEC-265 CTRP2 6.5926 7.9647 5.4936 1.4461
KLE CTRP2 7.0695 9.1863 5.2233 1.9027
HEC-108 CTRP2 7.4726 10.4456 4.8895 2.6917
EFE-184 CTRP2 8.1353 14.8031 3.2613 8.1532
Ishikawa (Heraklio) 02 ER- CTRP2 6.9634 9.5473 4.9869 2.9527
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RXF 393L GDSC1 1.1597 10.2276 -2.0648 39.7983
OS-RC-2 GDSC1; CTRP2 3.031 13.9016 -0.6106 31.5949
LB996-RCC GDSC1 3.3621 8.2457 0.8934 18.2715
UO-31 CTRP2 3.7571 15.5501 -0.7273 30.0157
A-498 GDSC1; CTRP2 3.9208 12.0767 1.1164 24.4567
LB1047-RCC GDSC1 4.1656 7.5816 1.8477 8.8385
CAL-54 CTRP2 4.4033 10.0708 2.5409 18.1371
TK-10 GDSC1 4.8818 10.3009 1.0313 12.5042
LB2241-RCC GDSC1 5.012 10.9602 0.8031 13.5845
TUHR10TKB CTRP2 5.2325 7.351 4.6333 7.7104
HA7-RCC GDSC1 5.3045 11.5484 0.7206 13.3061
KMRC-3 CTRP2 5.5736 13.3794 1.9776 17.6333
VMRC-RCW CTRP2 5.607 9.5811 3.8994 9.8937
KMRC-1 CTRP2 5.8363 12.3036 2.7397 14.1696
Caki-2 CTRP2 6.046 9.1639 4.4859 6.5474
TUHR4TKB CTRP2 6.0986 10.8075 3.7079 9.7043
BFTC-909 CTRP2 6.1771 8.4074 4.9716 4.2596
BB65-RCC GDSC1 6.1897 22.567 -4.0277 28.8796
ACHN CTRP2 6.6017 9.9049 4.5567 5.2564
786-O CTRP2 6.8936 10.5595 4.4495 5.2309
KMRC-20 CTRP2 6.9903 12.6077 3.5138 8.9117
KMRC-2 CTRP2 8.5436 19.8045 1.1197 15.2438
VMRC-RCZ CTRP2 8.68 20.2378 1.0063 15.397
SNU-1272 CTRP2 8.689 15.0686 3.4999 6.4945
769-P CTRP2 10.0143 21.5819 0.4594 11.341
RCC10RGB GDSC1; CTRP2 11.0337 22.7187 1.4078 10.8863
Caki-1 CTRP2 12.4421 26.0346 0.7443 11.2617
TUHR14TKB CTRP2 12.5258 42.7366 -7.2205 27.0018
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 50 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LoVo CTRP2 1.1436 7.7606 0.1457 35.5609
CL-34 CTRP2 4.0321 11.2481 1.621 22.4655
SW48 CTRP2 4.1423 7.3276 3.5177 14.9736
MDST8 GDSC1; CTRP2 4.1534 7.2449 3.5627 14.7699
CCK-81 CTRP2 4.4174 6.9147 3.9734 12.4618
HT115 CTRP2 4.5929 6.6789 4.251 10.9108
GP2d CTRP2 4.9423 7.4309 4.3046 9.7615
COLO 320 CTRP2 5.1366 9.7788 3.3755 13.0848
T84 CTRP2 5.2076 10.336 3.1668 13.7783
C2BBe1 GDSC1; CTRP2 5.2167 12.2558 2.2246 17.4749
SK-CO-1 CTRP2 5.2407 6.7526 4.9079 6.5959
HCC2998 GDSC1 5.2513 10.1501 1.3507 9.4677
SNU-C1 GDSC1; CTRP2 5.3911 6.7504 5.0644 5.5829
NCI-H747 GDSC1; CTRP2 5.5039 10.6553 3.2743 12.6983
LS1034 GDSC1; CTRP2 5.6079 6.888 5.2202 4.4107
CL-11 GDSC1; CTRP2 5.6251 10.2207 3.5972 11.1124
SNU-407 CTRP2 5.6272 8.2981 4.5535 7.1214
OUMS-23 CTRP2 5.6279 7.3355 5.0258 5.1596
HCT 15 CTRP2 5.7574 6.8164 5.3992 3.3218
CW-2 GDSC1; CTRP2 5.8117 7.9771 4.8778 5.3719
SNU-C5 CTRP2 5.8195 10.2805 3.7361 10.1362
COLO 320HSR GDSC1 5.8954 7.3775 2.847 0.1837
SW1417 CTRP2 5.8994 9.045 4.4216 7.1059
LS513 GDSC1; CTRP2 5.911 7.4275 5.2387 3.6531
NCI-H716 GDSC1; CTRP2 5.9883 8.3651 4.8369 5.1847
SNU-1033 CTRP2 6.084 10.983 3.608 10.1476
HT-55 CTRP2 6.1711 7.3359 5.5009 2.0513
SW620 CTRP2 6.1824 7.7353 5.311 2.8262
SNU-61 CTRP2 6.265 8.2562 5.1165 3.4946
SW948 CTRP2 6.2722 8.039 5.23 3.0079
DLD-1 CTRP2 6.3695 7.4737 5.5792 1.4096
SNU-C4 CTRP2 6.3991 7.5098 5.582 1.3562
NCI-H508 CTRP2 6.4023 9.8627 4.4247 6.1473
SNU-C2A CTRP2 6.5035 12.7512 1.5656 7.6599
LS123 GDSC1; CTRP2 6.5068 9.4499 4.71 4.7773
HCT 8 CTRP2 6.5101 8.2959 5.2792 2.4209
COLO201 CTRP2 6.5462 8.5236 5.194 2.7143
COLO 678 CTRP2 6.6107 8.9225 5.0457 3.2229
RCM-1 [Human ESC] CTRP2 6.635 7.89 5.555 1.1578
SW1116 CTRP2 6.6474 14.9069 2.1051 17.0597
LS180 CTRP2 6.8908 10.0417 4.6996 4.2128
RKO GDSC1; CTRP2 6.9494 12.0265 3.77 7.9334
HCC-56 CTRP2 7.0572 7.952 5.7455 0.2167
SNU-503 CTRP2 7.0831 11.211 4.2672 5.6855
HT-29 CTRP2 7.0937 8.7239 5.445 1.0757
SNU-175 CTRP2 7.1546 9.8407 4.9724 2.7595
KM12 GDSC1; CTRP2 7.4168 16.2115 2.0544 13.8605
HCT 116 CTRP2 7.7486 9.2971 5.5252 0.4006
LS411N GDSC1; CTRP2 7.8027 9.0701 5.6311 0.1781
COLO205 CTRP2 7.9587 9.084 5.6833 0.0803
⏷ Show the Full List of 50 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 5.6828 7.5541 2.7054 0.6458
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuH-6 CTRP2 4.4818 8.998 3.1248 15.6436
SNU-182 CTRP2 4.4874 19.09 -1.8174 30.6863
SNU-398 CTRP2 4.5179 8.5816 3.3541 14.6381
Li-7 CTRP2 5.1413 7.1532 4.6311 7.9498
Hep 3B2.1-7 CTRP2 5.1466 7.0844 4.1082 4.0092
SNU-886 CTRP2 5.2941 8.0212 4.3775 9.9389
JHH-4 CTRP2 5.4731 9.6435 3.7491 10.8041
SNU-449 CTRP2 5.7607 8.2305 4.7068 6.1953
JHH-1 CTRP2 6.0883 7.3473 5.4292 2.5025
SNU-387 CTRP2 6.1386 9.0802 4.6042 5.874
HuH-1 CTRP2 6.1622 7.4588 5.4328 2.3519
PLC/PRF/5 CTRP2 6.2725 8.5287 4.9869 4.024
HLF CTRP2 6.2845 8.2124 5.1534 3.3067
Hep-G2 CTRP2 6.3597 9.6257 4.5093 5.8688
JHH-5 CTRP2 6.4079 8.0833 5.3097 2.4532
SK-HEP-1 CTRP2 6.4592 7.7753 5.4955 1.6189
SNU-475 CTRP2 6.8496 14.6165 2.4095 13.5268
JHH-6 CTRP2 7.0601 7.9035 5.765 0.1752
SNU-423 CTRP2 7.08 13.7827 3.0008 10.8234
JHH-2 CTRP2 9.2764 24.0563 -0.4307 18.6962
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 174 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1184 CTRP2 2.7707 9.0239 1.3748 26.72
NCI-H1435 CTRP2 3.079 5.692 2.8971 20.3847
HCC44 CTRP2 3.3063 10.1062 1.4434 24.9798
EPLC-272H CTRP2 3.7872 9.5289 2.1893 21.0299
COR-L88 GDSC1 3.957 11.5593 -0.2801 22.7645
NCI-H1304 GDSC1 4.0141 5.7349 2.632 3.3858
NCI-H1648 GDSC1 4.1543 8.4932 1.393 12.1712
LXF 289 GDSC1; CTRP2 4.1985 9.8218 2.4602 18.9537
NCI-H345 GDSC1 4.2325 5.1062 3.0267 0.4795
NCI-H1436 GDSC1 4.245 6.8707 2.2453 5.664
NCI-H1734 CTRP2 4.3167 7.7716 3.5136 14.5211
EBC-1 CTRP2 4.3301 6.7696 3.9353 12.8523
NCI-H2135 GDSC1 4.4661 7.1096 2.2755 4.9049
NCI-H1341 CTRP2 4.5319 5.9925 4.4076 10.5096
NCI-H1703 CTRP2 4.6922 7.7835 3.8929 12.0435
NCI-H720 GDSC1 4.7675 10.7344 0.7405 14.651
SW1573 CTRP2 4.7801 9.2869 3.2782 14.3054
NCI-H520 CTRP2 4.7924 10.1062 2.8947 15.8174
NCI-H1836 GDSC1 4.8184 6.4917 2.7425 1.2486
HCC827 CTRP2 4.8644 8.7738 3.6043 12.7821
NCI-H1385 CTRP2 4.8933 7.5769 4.1895 10.3461
LC-2/ad GDSC1 4.9001 11.5357 0.4445 16.0259
Lu-139 GDSC1 4.9647 6.7752 2.6965 1.3151
NCI-H64 GDSC1 4.9751 7.0515 2.5881 1.8932
NCI-H187 GDSC1 4.9823 6.2835 2.8938 0.4355
CPC-N GDSC1 5.0645 11.1349 0.7551 13.7346
NCI-H1581 GDSC1; CTRP2 5.0843 6.9629 4.6558 8.0007
Lu-165 GDSC1 5.0893 6.5819 2.8263 0.6075
DMS 53 CTRP2 5.1269 7.0166 4.6765 7.8069
EKVX GDSC1; CTRP2 5.1409 12.3416 2.1144 18.0569
NCI-H1975 GDSC1 5.148 12.6117 0.097 17.2435
DMS 454 CTRP2 5.1488 9.1852 3.6769 11.8206
T3M-10 CTRP2 5.1513 11.4598 2.5606 16.3243
NCI-H2085 CTRP2 5.1577 9.6334 3.4663 12.666
HCC2935 CTRP2 5.2338 12.157 2.2888 17.1933
NCI-H82 GDSC1 5.2483 7.4869 2.5416 1.7895
SBC-1 GDSC1 5.2776 7.863 2.3997 2.5524
NCI-H128 GDSC1 5.2891 6.8409 2.8109 0.5286
NCI-H1793 CTRP2 5.2981 21.4847 -2.3061 29.9545
NCI-H510A GDSC1 5.2986 7.3713 2.6117 1.3679
CAL-12T CTRP2 5.3111 10.8477 3.0073 14.1977
NCI-H209 GDSC1 5.3155 8.179 2.2846 3.1864
LB647-SCLC GDSC1 5.3625 7.4585 2.6062 1.3271
NCI-H211 GDSC1; CTRP2 5.3641 8.5874 4.1694 9.3002
IST-SL2 GDSC1 5.3658 9.4732 1.7366 6.6452
NCI-H2227 GDSC1 5.3854 7.3894 2.6434 1.1289
DV-90 CTRP2 5.3865 6.8801 5.0023 5.8412
NCI-H1770 GDSC1 5.402 6.8103 2.8653 0.3061
HCC33 GDSC1 5.4362 7.0121 2.8062 0.4584
NCI-H1573 CTRP2 5.4444 8.0666 4.4981 7.7585
NCI-H1623 CTRP2 5.4515 7.9282 4.572 7.4371
Sq-1 CTRP2 5.455 11.8988 2.6126 15.4619
LUDLU-1 CTRP2 5.4579 7.0335 5.0042 5.6537
SK-MES-1 CTRP2 5.4711 8.2073 4.4546 7.8778
NCI-H1568 CTRP2 5.4904 6.6479 5.2112 4.7427
RERF-LC-MS CTRP2 5.5061 7.3885 4.8841 6.0262
NCI-H1155 GDSC1; CTRP2 5.5193 7.6673 4.7624 6.4957
NCI-H1876 GDSC1 5.5229 7.22 2.7645 0.5432
NCI-H661 CTRP2 5.5311 12.0099 2.6238 15.2569
NCI-H1944 CTRP2 5.5362 7.9489 4.6414 6.9576
NCI-H1693 CTRP2 5.5559 9.021 4.1316 9.0344
NCI-H2141 GDSC1; CTRP2 5.5907 7.3338 4.9913 5.3879
NCI-H1755 CTRP2 5.6011 14.8179 1.283 20.0321
NCI-H69 GDSC1; CTRP2 5.6022 8.6564 4.3537 8.0085
NCI-H2110 CTRP2 5.6521 7.2498 5.09 4.8391
NCI-H524 GDSC1; CTRP2 5.685 8.5533 4.4791 7.3076
NCI-H2405 CTRP2 5.6933 10.3922 3.5714 11.0781
NCI-H647 CTRP2 5.7168 11.6813 2.9485 13.5788
NCI-H1963 GDSC1 5.7176 7.6015 2.7018 0.6362
Ms-1 GDSC1 5.7188 7.5338 2.727 0.5522
NCI-H847 GDSC1 5.7259 7.033 2.9044 0.1296
NCI-H2196 GDSC1; CTRP2 5.7375 8.2879 4.6577 6.4496
A-549 CTRP2 5.7485 9.092 4.2675 8.0599
NCI-H2081 GDSC1; CTRP2 5.7499 9.0463 4.2914 7.9567
NCI-H2171 GDSC1; CTRP2 5.7551 6.7156 5.4452 3.1388
NCI-H1339 CTRP2 5.7609 9.6509 3.9997 9.1549
COR-L105 CTRP2 5.8083 8.7133 4.5084 6.9267
NCI-H2126 CTRP2 5.81 9.6008 4.0672 8.7723
NCI-H810 CTRP2 5.8153 7.2517 5.2406 3.8487
NCI-H1395 CTRP2 5.8336 7.8752 4.9479 5.0327
NCI-H2029 CTRP2 5.841 6.8355 5.4687 2.8432
NCI-H23 GDSC1; CTRP2 5.8425 7.6489 5.0682 4.5104
NCI-H2023 CTRP2 5.8521 9.5755 4.1161 8.4826
VMRC-LCD CTRP2 5.8523 8.229 4.7882 5.6632
ChaGo-K-1 CTRP2 5.861 7.8676 4.9758 4.8586
COLO 668 GDSC1; CTRP2 5.8817 8.8791 4.4893 6.8574
NCI-H1650 GDSC1; CTRP2 5.8977 12.6582 2.6145 14.5398
NCI-H322M GDSC1 5.8986 8.4969 2.4372 1.5827
DMS 114 GDSC1; CTRP2 5.9011 9.1664 4.3625 7.3508
NCI-H446 GDSC1; CTRP2 5.9074 13.3263 2.2887 15.7798
NCI-H2122 CTRP2 5.9417 7.6043 5.1773 3.8479
HCC366 CTRP2 5.9446 9.3225 4.3214 7.4367
COR-L47 CTRP2 5.9447 20.4206 -1.227 26.4136
NCI-H1915 CTRP2 5.9552 6.8919 5.5442 2.281
MOR/CPR CTRP2 5.9713 6.6635 5.672 1.7121
NCI-H2009 CTRP2 6.002 9.9484 4.0569 8.4334
NCI-H838 CTRP2 6.0232 8.7476 4.6751 5.7968
DMS 273 CTRP2 6.0298 13.1374 2.4857 14.7787
NCI-H1666 GDSC1; CTRP2 6.0307 22.1155 -2.0026 27.9367
HCC15 CTRP2 6.0317 9.8276 4.1422 8.0183
LK2 CTRP2 6.0463 6.7986 5.6689 1.5749
NCI-H841 CTRP2 6.0483 7.2878 5.426 2.5919
NCI-H727 CTRP2 6.0551 8.0808 5.0351 4.2216
NCI-H2342 CTRP2 6.0583 9.0175 4.5693 6.1733
NCI-H748 GDSC1 6.0604 8.0086 2.6874 0.4938
NCI-H358 CTRP2 6.0732 10.9059 3.6376 10.0453
NCI-H1694 GDSC1; CTRP2 6.0932 7.5186 5.3476 2.8362
NCI-H522 CTRP2 6.0982 8.5145 4.8539 4.9011
COR-L95 GDSC1; CTRP2 6.103 8.8695 4.6804 5.6214
NCI-H1092 GDSC1; CTRP2 6.1493 7.5689 5.3677 2.6481
NCI-H526 GDSC1; CTRP2 6.1521 8.3389 4.9856 4.247
IST-SL1 GDSC1 6.1781 7.7097 2.833 0.1436
NCI-H1105 CTRP2 6.2086 8.0409 5.1795 3.3305
NCI-H1838 GDSC1; CTRP2 6.2117 9.5246 4.4417 6.4203
HCC95 CTRP2 6.232 7.9337 5.2511 2.9895
Lu-99 CTRP2 6.2367 7.8919 5.2756 2.8789
NCI-H2170 CTRP2 6.2811 8.1364 5.1885 3.1656
LCLC-97TM1 CTRP2 6.3132 8.7701 4.8985 4.3221
LOU-NH91 CTRP2 6.34 9.8795 4.3673 6.4986
NCI-H322 CTRP2 6.3545 7.5917 5.5115 1.7077
NCI-H1373 CTRP2 6.3651 12.9306 2.8648 12.6414
RERF-LC-Ad2 CTRP2 6.3728 9.8817 4.3921 6.3361
Calu-3 CTRP2 6.3838 10.7929 3.9467 8.1773
NCI-H2106 CTRP2 6.4317 10.7718 3.9952 7.8888
LC-1/sq-SF CTRP2 6.436 7.5677 5.5792 1.3163
Lu-134-A GDSC1 6.4408 8.2378 2.7461 0.2231
Calu-6 GDSC1; CTRP2 6.5288 9.2861 4.8074 4.3361
NCI-H1299 GDSC1; CTRP2 6.5764 9.3505 4.8111 4.2433
NCI-H650 CTRP2 6.5978 11.3837 3.8208 8.3203
SHP-77 GDSC1; CTRP2 6.6225 11.7115 3.677 8.8711
HCC2108 CTRP2 6.6459 10.2252 4.4317 5.702
IA-LM CTRP2 6.7193 9.3182 4.9301 3.5305
HARA [Human squamous cell lung carcinoma] CTRP2 6.7535 9.4138 4.9078 3.5701
DMS 79 GDSC1; CTRP2 6.7606 13.1402 3.0743 11.0829
NCI-H292 CTRP2 6.7863 11.5594 3.8781 7.76
HCC2279 CTRP2 6.8206 16.3951 1.5008 16.8866
RERF-LC-Ad1 CTRP2 6.8457 10.5765 4.4064 5.483
SBC-5 CTRP2 7.0183 8.2902 5.5917 0.6576
NCI-H889 CTRP2 7.0236 9.9957 4.8132 3.5624
COLO 699 CTRP2 7.0656 14.4003 1.1514 8.5738
LCLC-103H CTRP2 7.068 9.8538 4.9103 3.1153
NCI-H1651 CTRP2 7.088 19.9061 -0.0371 21.2142
NCI-H1563 CTRP2 7.1653 23.1369 -1.5866 24.9799
NCI-H2291 CTRP2 7.1699 15.8139 2.063 14.2549
SK-LU-1 CTRP2 7.1744 12.7512 3.5798 8.3427
NCI-H196 CTRP2 7.2276 16.6028 1.7159 15.4028
NCI-H2030 CTRP2 7.2409 14.7876 2.6255 12.017
HCC4006 CTRP2 7.2668 11.1235 4.4372 4.7276
HCC1833 CTRP2 7.3075 12.8024 3.6515 7.842
HCC78 CTRP2 7.3215 13.2785 3.4286 8.7174
NCI-H460 CTRP2 7.3259 14.4746 2.8438 11.0287
SW1271 CTRP2 7.4072 22.7197 -1.1865 23.6322
HCC1588 CTRP2 7.4241 13.5724 3.3591 8.8333
NCI-H441 CTRP2 7.5351 9.9294 5.1585 1.6466
NCI-H1355 GDSC1; CTRP2 7.549 24.1516 -1.7879 24.7677
BEN CTRP2 7.5782 8.6725 5.6878 0.1492
NCI-H1869 GDSC1; CTRP2 7.6212 14.4309 3.0816 9.6226
KNS-62 CTRP2 8.2249 15.4833 2.9954 9.0481
NCI-H1792 CTRP2 8.2546 16.5234 2.5131 10.8247
NCI-H226 GDSC1; CTRP2 8.3346 21.3279 0.2172 18.3545
NCI-H2172 CTRP2 8.4044 17.3473 2.2185 11.6805
NCI-H2286 CTRP2 8.7672 16.4214 2.9119 8.6033
HOP-62 GDSC1; CTRP2 8.9447 24.4076 -0.8465 20.2834
NCI-H2087 CTRP2 8.9689 23.0437 -0.1583 18.4216
PC-14 CTRP2 9.2304 31.7228 -4.2459 26.8289
RERF-LC-A1 CTRP2 9.3132 20.6639 1.247 13.6754
NCI-H2228 CTRP2 9.9311 31.6321 -3.6724 24.8688
HCC1195 CTRP2 10.4174 19.1454 2.68 7.3979
HOP-92 CTRP2 10.6593 33.3141 -3.9617 24.402
Lu-65 GDSC1; CTRP2 10.8502 25.0415 0.1908 14.7723
HCC1438 CTRP2 11.2519 23.9162 0.986 11.9276
HCC1171 CTRP2 12.3015 26.1154 0.6204 11.7761
Calu-1 CTRP2 12.958 27.2288 0.5091 11.367
Hs 888.Lu CTRP2 6.8125 13.9637 2.7053 12.4519
⏷ Show the Full List of 174 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 5.7198 13.8679 -0.1111 16.7991
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 4.1685 10.4477 2.1347 20.2618
JHOM-1 CTRP2 3.8825 9.9971 2.0676 21.2349
IGROV-1 CTRP2 4.1245 6.4405 3.829 13.8435
A2780 CTRP2 4.179 8.0698 3.2421 15.9495
SNU-840 CTRP2 4.9993 9.9013 3.1882 14.1595
Caov-3 CTRP2 5.1541 9.446 3.5546 12.3114
ONCO-DG-1 CTRP2 5.2878 11.4563 2.6847 15.5375
FU-OV-1 CTRP2 5.403 18.5233 -0.7373 26.3348
COV434 CTRP2 5.5018 7.3888 4.8797 6.0543
SNU-119 CTRP2 5.5436 11.0899 3.093 13.3538
OVK18 CTRP2 5.5763 7.8657 4.7193 6.5446
OVCAR-4 GDSC1; CTRP2 5.8549 11.7525 3.031 12.9655
OAW28 CTRP2 5.8644 11.1372 3.3465 11.6594
OVTOKO CTRP2 5.9058 11.928 2.9864 13.0437
TOV-112D CTRP2 5.9221 7.6395 5.1428 4.0326
MCAS CTRP2 6.0154 9.3097 4.3875 7.0202
ES-2 GDSC1 6.0383 7.6432 2.8068 0.2188
TYK-nu CTRP2 6.0407 8.2504 4.9383 4.6564
OAW42 CTRP2 6.0584 6.8806 5.6379 1.6818
OV-90 CTRP2 6.1329 7.1521 5.5624 1.8613
DOV13 CTRP2 6.2498 8.2486 4.3003 1.5304
EFO-27 CTRP2 6.2696 8.3044 5.0961 3.5719
OC 314 CTRP2 6.307 9.25 4.6549 5.3531
SNU-8 CTRP2 6.3741 9.1896 4.7375 4.8891
COV362 CTRP2 6.3809 8.8441 4.9141 4.1397
Kuramochi GDSC1; CTRP2 6.3892 14.9247 1.8882 16.3235
OV56 CTRP2 6.4184 8.9404 4.895 4.1557
OVISE CTRP2 6.4477 8.2714 4.3959 1.0026
RMG-I CTRP2 6.4568 15.665 1.5733 17.3172
EFO-21 CTRP2 6.5646 8.6024 5.1687 2.7899
HEY A8 CTRP2 6.6915 10.7137 4.2247 6.4847
JHOS-2 CTRP2 6.8376 9.0184 5.1552 2.4554
OV7 CTRP2 6.8633 8.9367 5.2105 2.2039
ES2 CTRP2 6.8698 7.7164 4.7756 0.024
SK-OV-3 CTRP2 7.0836 11.1778 4.2837 5.6173
OVCAR-8 CTRP2 7.449 14.54 2.9027 10.5969
JHOC-5 CTRP2 7.6317 12.0234 4.2518 4.9623
OVSAHO CTRP2 8.3714 21.5314 0.1443 18.5065
OVCAR-5 CTRP2 9.1316 21.122 0.8978 15.0557
COV644 CTRP2 10.0485 25.1164 -0.3958 17.4802
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 4.5861 12.2544 1.6537 21.0039
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 4.8388 9.7525 3.1099 14.8465
Aska-SS CTRP2 5.5802 8.1302 4.5932 7.0593
Rh41 CTRP2 3.7445 5.8812 3.5771 15.9037
A-204 CTRP2 4.1921 11.1556 1.8185 21.3645
VA-ES-BJ GDSC1 4.4685 6.6871 2.4717 3.5143
G-401 CTRP2 4.9757 9.8057 3.2128 14.1135
SW684 GDSC1 5.0032 25.5484 -6.4232 35.463
KYM-1 CTRP2 5.215 8.9998 3.8292 11.0432
G-402 CTRP2 5.2183 8.3329 4.1554 9.6925
MFH-ino GDSC1 5.2491 14.4494 -0.7289 20.9349
TE 441.T GDSC1; CTRP2 5.8309 9.8995 3.9362 9.2781
RD CTRP2 5.8605 8.2112 4.8042 5.5792
EW-8 GDSC1 5.8816 7.1892 2.9054 0.1001
TE 617.T CTRP2 5.9091 7.0547 5.4225 2.8872
Rh18 CTRP2 6.0919 15.5576 1.3274 18.8779
BT-16 CTRP2 6.1171 7.2236 5.5143 2.0918
GCT CTRP2 6.1201 13.396 2.4315 14.8102
TTC-709 CTRP2 6.1393 8.3864 4.9515 4.4139
SW872 GDSC1 6.1915 22.6858 -4.085 29.0009
HT-1080 CTRP2 6.3516 7.6628 5.4747 1.8629
Tm87-16 CTRP2 6.4373 8.0845 5.3303 2.3228
RKN CTRP2 6.7034 9.1267 5.0119 3.221
SK-UT-1 GDSC1; CTRP2 6.7241 12.3712 3.428 9.7155
Hs 729.T CTRP2 6.8096 9.1513 5.0731 2.8207
BT-12 CTRP2 7.2131 7.9916 5.7923 0.0856
SW982 CTRP2 7.345 15.2381 2.4814 12.3921
MES-SA CTRP2 7.3754 8.8642 5.5288 0.5924
SK-LMS-1 GDSC1; CTRP2 9.1518 21.0223 0.9605 14.8284
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
H-STS CTRP2 6.0049 7.6619 5.2025 3.6159
P-STS CTRP2 6.2304 11.9309 3.2547 11.3225
SYO-1 CTRP2 9.5945 24.6784 -0.5053 18.4237
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; CTRP2 4.9837 9.8315 3.2077 14.116
NCI-H2452 CTRP2 5.031 14.1471 1.1204 21.809
NCI-H28 CTRP2 5.9603 7.9621 5.0146 4.4936
NCI-H2052 CTRP2 7.901 14.335 3.3258 8.2407
IST-Mes1 GDSC1; CTRP2 8.4382 14.282 3.7087 6.019
ACC-MESO-1 CTRP2 8.5963 18.8235 1.6365 13.4398
MPP 89 GDSC1; CTRP2 9.3702 20.7468 1.2464 13.5954
JL-1 CTRP2 9.8138 15.6604 3.8955 3.8343
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1; CTRP2 3.2303 6.9835 2.6739 20.7426
VCaP GDSC1; CTRP2 5.2169 6.4416 5.0086 6.2713
22Rv1 CTRP2 5.78 8.5036 3.8829 3.8913
DU145 CTRP2 6.5906 9.9536 4.5242 5.4094
PaCa-3 CTRP2 7.041 12.2032 3.7509 7.8618
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 5.4896 7.2276 2.7485 0.6184
YD-15 CTRP2 5.5945 11.6176 2.8746 14.1285
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 6.3566 16.297 -0.8438 18.6238
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Fu97 CTRP2 3.5725 6.2421 3.2903 17.4626
HGC-27 CTRP2 3.7716 5.8325 3.6185 15.6727
23132/87 CTRP2 4.3478 7.1909 3.79 13.3595
SNU-5 GDSC1; CTRP2 4.5304 7.2404 3.9615 12.1981
RF-48 GDSC1 4.6175 10.1103 0.9375 13.8509
SNU-1 GDSC1; CTRP2 4.7184 8.6873 3.5029 13.5454
SCH GDSC1 4.7577 5.9295 2.9345 0.4369
SNU-216 CTRP2 4.9876 9.3565 3.4422 13.1525
GSS CTRP2 5.1005 6.6929 4.7858 7.4499
SNU-620 CTRP2 5.3353 7.0087 4.8926 6.4103
HSC-39 GDSC1 5.5365 7.2571 2.7563 0.5622
SNU-16 GDSC1; CTRP2 5.575 6.3428 5.4283 3.6669
IM95 CTRP2 5.6642 7.0889 5.1793 4.4435
ECC10 CTRP2 5.697 7.2917 5.112 4.6456
GCIY GDSC1 5.8301 25.4214 -5.7134 32.7744
MKN74 CTRP2 5.8877 11.4606 3.2046 12.1942
SNU-668 CTRP2 5.9237 9.9444 3.9929 8.8554
HuG1-N CTRP2 5.9286 8.0811 4.928 4.921
NUGC-4 CTRP2 5.9318 13.8822 2.0312 16.6979
NCI-N87 GDSC1 5.9542 10.6751 1.5382 6.7268
SNU-601 CTRP2 6.0747 9.3812 4.4012 6.8482
NUGC-3 CTRP2 6.0848 8.2493 4.9754 4.416
Hs 746.T CTRP2 6.1306 9.2377 4.519 6.2472
MKN1 CTRP2 6.1834 8.956 4.7028 5.3767
KATO III CTRP2 6.2706 8.6808 4.9096 4.3507
SNU-719 CTRP2 6.2962 9.1142 4.714 5.1246
KE-39 CTRP2 6.2972 14.7055 1.9227 16.3752
OCUM-1 CTRP2 6.3255 8.2221 5.18 3.1255
SH-10-TC CTRP2 6.4344 8.1262 5.3079 2.4192
MKN7 CTRP2 6.4516 9.5918 4.5975 5.3396
LMSU CTRP2 6.7657 10.4004 4.4344 5.495
GSU CTRP2 6.8406 7.4139 5.8574 0.0803
AGS CTRP2 6.8769 10.1705 4.6273 4.5287
ECC12 GDSC1; CTRP2 7.2939 11.3882 4.3285 5.1258
MKN45 CTRP2 7.3088 8.159 5.7689 0.0964
SNG-M CTRP2 5.5952 10.4263 3.4687 11.7063
SNU-1077 CTRP2 5.8405 8.3037 4.7407 5.8866
SNU-685 CTRP2 6.3381 8.2273 5.187 3.0753
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
K5 GDSC1 4.7787 7.5516 2.2625 4.3139
8305C CTRP2 4.9675 9.9465 3.1365 14.4413
TT CTRP2 5.8698 11.3744 3.2325 12.1161
SW579 CTRP2 5.9397 8.9248 4.5161 6.6289
CGTH-W-1 GDSC1; CTRP2 6.1411 9.0594 4.6167 5.8171
B-CPAP CTRP2 6.1528 8.1295 5.0907 3.8043
FTC-238 CTRP2 6.1858 9.2025 4.5816 5.8812
CAL-62 CTRP2 6.3337 8.4681 5.0644 3.5935
TT2609-C02 CTRP2 6.4061 8.5103 5.0984 3.3306
BHT-101 CTRP2 6.4911 10.8339 4.0109 7.718
FTC-133 CTRP2 7.0898 11.2813 4.2378 5.795
ML-1 [Human leukemia] CTRP2 7.4361 20.3388 0.0213 20.4303
8505C CTRP2 9.0605 20.7583 1.0243 14.7619
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BB49-HNC GDSC1 -4.1115 10.0728 -7.2748 62.617
YD-10B CTRP2 4.8784 8.7838 3.613 12.713
LB771-HNC GDSC1 4.8953 7.0525 2.5472 2.251
BB30-HNC GDSC1 5.3022 12.3556 0.33 15.5634
SCC-25 CTRP2 5.3274 9.8629 3.509 12.1131
SCC-4 CTRP2 5.6795 42.871 -12.6739 39.7678
Detroit 562 CTRP2 5.6889 9.0345 3.5577 5.4738
BICR 18 CTRP2 5.749 8.5778 4.5238 6.9853
SNU-1214 CTRP2 5.7717 10.9803 3.3457 11.8498
HSC-3 CTRP2 5.9071 7.7225 4.3378 1.7783
SNU-1076 CTRP2 6.0049 9.4349 4.3161 7.3406
SCC-15 GDSC1 6.0422 8.0515 2.665 0.5692
BICR 31 CTRP2 6.1398 9.1318 4.5794 5.976
HSC-2 CTRP2 6.158 7.071 5.6224 1.5663
PE/CA-PJ15 CTRP2 6.1729 7.9716 5.1857 3.3691
PE/CA-PJ34 (clone C12) CTRP2 6.1757 7.768 5.2895 2.9286
BICR 6 CTRP2 6.1829 8.2687 5.0454 3.9393
BHY CTRP2 6.1941 9.7685 4.3056 7.0238
SCC-9 CTRP2 6.343 8.8363 4.8889 4.3104
CAL-27 CTRP2 6.3474 8.8307 4.895 4.2773
BICR 22 CTRP2 6.3851 7.6348 5.5121 1.659
PE/CA-PJ49 CTRP2 6.419 8.7675 4.9811 3.7966
SNU-899 CTRP2 6.4386 9.5974 4.5848 5.4151
YD-8 CTRP2 6.4537 12.1283 3.3364 10.5729
FaDu CTRP2 6.4829 7.7849 5.5069 1.5399
CAL-33 CTRP2 6.6357 10.2094 4.4318 5.7182
BICR 16 CTRP2 6.788 10.4465 4.4281 5.4853
HSC-4 CTRP2 7.0582 12.1018 3.8135 7.5786
PE/CA-PJ41 (clone D2) CTRP2 7.4704 11.0179 4.6219 3.7214
SNU-1066 CTRP2 7.7692 12.6975 4.0222 5.6821
SNU-46 CTRP2 8.4363 16.3598 2.7183 9.7908
SNU-1041 CTRP2 8.6922 18.0092 2.0991 11.6805
BICR 56 CTRP2 11.4215 27.2104 -0.4625 15.8212
⏷ Show the Full List of 33 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
253J CTRP2 4.6105 6.9634 4.1592 11.2133
SW1710 CTRP2 4.8802 14.2968 0.9118 22.8246
JMSU-1 CTRP2 4.9137 8.0898 3.9747 11.1595
U-BLC1 CTRP2 5.5512 12.9851 2.155 17.0194
VM-CUB-1 CTRP2 6.0891 8.7056 4.7509 5.3513
CAL-29 CTRP2 6.1765 8.3137 5.0178 4.0667
5637 CTRP2 6.2145 13.47 2.4724 14.4685
647V CTRP2 6.2888 8.8161 4.8566 4.5407
TCCSUP CTRP2 6.3921 10.385 4.1567 7.2861
UM-UC-3 CTRP2 6.4065 13.6563 2.5358 13.8565
UM-UC-1 CTRP2 6.5558 7.9658 5.4692 1.5906
HT-1197 CTRP2 6.562 8.2868 5.3197 2.18
SCaBER CTRP2 6.6235 8.9622 5.0354 3.2453
RT-4 CTRP2 6.714 10.5396 4.3275 6.0216
T24 CTRP2 6.7229 9.7541 4.7201 4.3857
RT-112 CTRP2 6.7704 10.3333 4.4708 5.3372
J82 CTRP2 6.7881 10.1403 4.5783 4.8666
KU-19-19 CTRP2 6.8035 8.614 5.3237 1.8394
BC-3C CTRP2 6.8847 8.4827 5.434 1.3265
639V CTRP2 7.1638 8.2914 5.6605 0.3657
KMBC-2 CTRP2 7.8605 13.2357 3.8265 6.3283
BFTC-905 CTRP2 8.0191 9.2661 5.6423 0.1148
HT-1376 CTRP2 8.0486 15.6453 2.7943 10.0767
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 12 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KGN GDSC1 3.3385 7.3485 1.3224 15.429
NT2-D1 GDSC1 3.798 6.8085 1.9577 9.1179
NCC-IT GDSC1 4.1782 6.1626 2.536 3.6963
NEC8 GDSC1 4.7966 6.3575 2.7863 1.0495
SW954 GDSC1 4.8288 6.8911 2.5815 2.1466
JAR GDSC1 5.1107 12.7631 -0.0037 17.8725
SW962 GDSC1 5.2301 7.1138 2.6826 1.0987
DSH1 GDSC1 5.628 7.4559 2.7197 0.6307
OMC-1 [Human cervical carcinoma] GDSC1 5.6904 7.6135 2.6865 0.7073
TC-YIK GDSC1 5.8387 7.7657 2.6895 0.6046
HeLa CTRP2 6.2669 7.3161 5.5831 1.5496
LB831-BLC GDSC1 6.6462 19.3899 -2.1385 22.7913
⏷ Show the Full List of 12 Cancer Drug Sensitivity Data of This Drug

References

1 PI 3-kinase p110beta: a new target for antithrombotic therapy. Nat Med. 2005 May;11(5):507-14.
2 Estrogen-mediated inactivation of FOXO3a by the G protein-coupled estrogen receptor GPER. BMC Cancer. 2015 Oct 15;15:702. doi: 10.1186/s12885-015-1699-6.
3 Functional characterization of an isoform-selective inhibitor of PI3K-p110 as a potential anticancer agent. Cancer Discov. 2012 May;2(5):425-33. doi: 10.1158/2159-8290.CD-12-0003. Epub 2012 Apr 12.