Details of the Drug

General Information of Drug (ID: DMNA8HM)

Drug Name
Pyrithione Zinc
Synonyms Head & Shoulders Conditioner
Indication
Disease Entry ICD 11 Status REF
Seborrhoeic dermatitis EA81 Approved [1]
ATC Code
D11AX12: Pyrithione Zinc
D11AX: Other dermatologicals
D11A: OTHER DERMATOLOGICAL PREPARATIONS
D11: OTHER DERMATOLOGICAL PREPARATIONS
D: DERMATOLOGICALS
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski):
0		 Molecular Weight 317.7
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 0
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Chemical Identifiers
Formula
C10H8N2O2S2Zn
IUPAC Name
zinc;1-oxidopyridine-2-thione
Canonical SMILES
C1=CC(=S)N(C=C1)[O-].C1=CC(=S)N(C=C1)[O-].[Zn+2]
InChI
InChI=1S/2C5H4NOS.Zn/c2*7-6-4-2-1-3-5(6)8;/h2*1-4H;/q2*-1;+2
InChIKey
PICXIOQBANWBIZ-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
3005837
ChEBI ID
CHEMBL32076
CAS Number
13463-41-7
TTD ID
D0C8FX
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Drug ADMET Endpoint Profile (DAE)NEW Click to Jump to the Detailed DAE Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fungal Proton pump (FPPCM) TTG5TOX NOUNIPROTAC Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Mechanism of the antimicrobial action of pyrithione: effects on membrane transport, ATP levels, and protein synthesis. Antimicrob Agents Chemother. 1978 Jul;14(1):60-8.