Details of the Drug

General Information of Drug (ID: DMNA8HM)

Drug Name
Pyrithione Zinc
Synonyms Head & Shoulders Conditioner
Indication
Disease Entry ICD 11 Status REF
Seborrhoeic dermatitis EA81 Approved [1]
Drug Type
Small molecular drug
Structure
3D MOL is unavailable 2D MOL
#Ro5 Violations (Lipinski):
0		 Molecular Weight 317.7
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 0
Hydrogen Bond Donor Count 0
Hydrogen Bond Acceptor Count 4
Chemical Identifiers
Formula
C10H8N2O2S2Zn
IUPAC Name
zinc;1-oxidopyridine-2-thione
Canonical SMILES
C1=CC(=S)N(C=C1)[O-].C1=CC(=S)N(C=C1)[O-].[Zn+2]
InChI
InChI=1S/2C5H4NOS.Zn/c2*7-6-4-2-1-3-5(6)8;/h2*1-4H;/q2*-1;+2
InChIKey
PICXIOQBANWBIZ-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
3005837
ChEBI ID
CHEBI:32076
CAS Number
13463-41-7
TTD ID
D0C8FX

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fungal Proton pump (FPPCM) TTG5TOX NOUNIPROTAC Modulator [2]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 Mechanism of the antimicrobial action of pyrithione: effects on membrane transport, ATP levels, and protein synthesis. Antimicrob Agents Chemother. 1978 Jul;14(1):60-8.