Details of the Drug

General Information of Drug (ID: DMNE56X)

Drug Name
ABT-263
Synonyms
Navitoclax; ABT 263; S1001_Selleck; ABT263, Navitoclax; 4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({4-({(1R)-3-morpholin-4-yl-1-[(phenylsulfanyl)methyl]propyl}amino)-3-[(trifluoromethyl)sulfonyl]phenyl}sulfonyl)benzamide
Indication
Disease Entry ICD 11 Status REF
Myelofibrosis 2A20.2 Phase 3 [1]
Relapsed or refractory chronic lymphocytic leukaemia 2A82.0 Phase 2 [2]
Solid tumour/cancer 2A00-2F9Z Discontinued in Phase 2 [3]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 4 Molecular Weight (mw) 974.6
Logarithm of the Partition Coefficient (xlogp) 9.6
Rotatable Bond Count (rotbonds) 16
Hydrogen Bond Donor Count (hbonddonor) 2
Hydrogen Bond Acceptor Count (hbondacc) 14
Chemical Identifiers
Formula
C47H55ClF3N5O6S3
IUPAC Name
4-[4-[[2-(4-chlorophenyl)-5,5-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylbenzamide
Canonical SMILES
CC1(CCC(=C(C1)CN2CCN(CC2)C3=CC=C(C=C3)C(=O)NS(=O)(=O)C4=CC(=C(C=C4)N[C@H](CCN5CCOCC5)CSC6=CC=CC=C6)S(=O)(=O)C(F)(F)F)C7=CC=C(C=C7)Cl)C
InChI
InChI=1S/C47H55ClF3N5O6S3/c1-46(2)20-18-42(34-8-12-37(48)13-9-34)36(31-46)32-55-22-24-56(25-23-55)39-14-10-35(11-15-39)45(57)53-65(60,61)41-16-17-43(44(30-41)64(58,59)47(49,50)51)52-38(19-21-54-26-28-62-29-27-54)33-63-40-6-4-3-5-7-40/h3-17,30,38,52H,18-29,31-33H2,1-2H3,(H,53,57)/t38-/m1/s1
InChIKey
JLYAXFNOILIKPP-KXQOOQHDSA-N
Cross-matching ID
PubChem CID
24978538
ChEBI ID
CHEBI:94128
CAS Number
923564-51-6
UNII
XKJ5VVK2WD
DrugBank ID
DB12340
TTD ID
D06ETI
VARIDT ID
DR01365
INTEDE ID
DR1839
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug
Repurposed Drugs (RPD) Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Apoptosis regulator Bcl-2 (BCL-2) TTJGNVC BCL2_HUMAN Inhibitor [4]
Apoptosis regulator Bcl-W (BCL-W) TTQ79W8 B2CL2_HUMAN Inhibitor [4]
Apoptosis regulator Bcl-xL (BCL-xL) TTU1E82 B2CL1_HUMAN Inhibitor [4]
G1/S-specific cyclin-D1 (CCND1) TTFCJ7S CCND1_HUMAN Inhibitor [5]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [6]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4)
Main DME 		DE4LYSA CP3A4_HUMAN Substrate [7]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Gene/Protein Processing [8]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Protein Interaction/Cellular Processes [9]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Protein Interaction/Cellular Processes [9]
Gelsolin (GSN) OT4KS2UU GELS_HUMAN Protein Interaction/Cellular Processes [9]
Poly polymerase 1 (PARP1) OT310QSG PARP1_HUMAN Protein Interaction/Cellular Processes [8]
Serine/threonine-protein kinase mTOR (MTOR) OTHH8KU7 MTOR_HUMAN Drug Response [8]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Molecular Expression Atlas of This Drug

The Studied Disease Myelofibrosis
ICD Disease Classification 2A20.2
Molecule Name Molecule Type Gene Name p-value Fold-Change Z-score
Apoptosis regulator Bcl-2 (BCL-2) DTT BCL2 2.52E-02 0.17 0.72
P-glycoprotein 1 (ABCB1) DTP P-GP 1.08E-01 -2.87E-01 -5.57E-01
P-glycoprotein 1 (ABCB1) DTP P-GP 2.05E-01 1.60E-01 1.37E+00
Cytochrome P450 3A4 (CYP3A4) DME CYP3A4 3.18E-03 2.30E-01 2.71E+00
Cytochrome P450 3A4 (CYP3A4) DME CYP3A4 8.32E-01 4.74E-02 1.73E-01
Molecular Expression Atlas (MEA) Jump to Detail Molecular Expression Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1; GDSC2 2.3238 7.3087 0.4459 17.1768
EW-18 GDSC1; GDSC2 -3.7054 -0.0537 -3.7532 56.8299
EW-3 GDSC1; GDSC2 -2.6983 2.6974 -3.0887 49.1488
EW-22 GDSC1; GDSC2 -1.2788 2.4528 -1.4912 38.1865
EW-12 GDSC2 -0.9712 1.0728 -1.1715 20.8387
EW-13 GDSC1; GDSC2 -0.2147 6.2084 -1.997 30.2878
HuO9 GDSC1; GDSC2 -0.2043 5.2132 -1.1685 32.4374
SK-ES-1 GDSC1; GDSC2; CTRP2 -0.1081 5.361 -0.6682 35.9843
TC-71 GDSC1; GDSC2 0.4252 3.7532 0.0332 25.2489
CADO-ES1 GDSC1; GDSC2 0.5083 5.3825 -0.4819 27.1241
EW-11 GDSC1; GDSC2 0.6028 5.4025 -0.3909 26.4085
NOS-1 [Human HNSCC] GDSC1; GDSC2 0.6622 4.9449 -0.1423 25.1427
EW-7 GDSC1; GDSC2 0.875 8.0985 -1.3208 29.0066
ES5 GDSC1; GDSC2 0.9422 7.6931 -2.3948 20.4601
ES7 GDSC1; GDSC2 1.0183 4.1863 0.5283 20.8998
EW-1 GDSC1; GDSC2 1.1303 4.5771 0.4999 20.6377
EW-24 GDSC1; GDSC2 1.1346 6.9074 -0.5098 25.071
G-292 clone A141B1 GDSC1; GDSC2; CTRP2 1.885 5.8809 1.3365 22.9945
A-673 GDSC1; GDSC2; CTRP2 1.9205 4.3511 1.7963 21.2369
ES4 GDSC1; GDSC2 2.1778 5.1165 1.3549 13.1647
CHSA8926 GDSC1; GDSC2 2.4458 6.3435 1.0307 13.9852
U-CH2 GDSC2 2.4785 5.0211 0.0469 2.8541
CAL-72 GDSC1; GDSC2 2.5894 3.7383 2.3799 6.8992
NY GDSC1; GDSC2 2.6242 4.2462 2.1997 7.6508
CAL-78 GDSC1; GDSC2; CTRP2 2.6509 6.525 1.9189 18.626
SJSA-1 GDSC1; GDSC2; CTRP2 2.9109 4.0301 2.5859 4.508
SaOS-2 GDSC1; GDSC2; CTRP2 2.9535 6.2271 2.3579 16.1092
CHSA0108 GDSC1; GDSC2 2.9825 6.1476 -0.1698 3.2513
EW-16 GDSC1; GDSC2 3.1508 9.131 0.2736 15.8043
ES1 GDSC1; GDSC2 3.1708 6.9921 1.3594 10.4265
ES8 GDSC1; GDSC2 3.5879 10.6199 -0.1078 16.4837
ES6 GDSC1; GDSC2 3.741 8.8723 0.8877 11.4636
CHSA0011 GDSC1; GDSC2 3.861 5.9679 0.3114 0.475
SK-PN-DW GDSC1; GDSC2 4.4344 8.4521 1.6144 6.457
Hs 888.T CTRP2 4.4925 5.7839 4.1529 4.9691
U2OS GDSC1; GDSC2; CTRP2; CTRP1 4.8117 5.9689 4.3845 3.3477
H-EMC-SS GDSC1; GDSC2 5.7776 12.9484 0.3694 9.9663
HuO-3N1 GDSC1; GDSC2 5.8703 14.342 -0.2361 12.4017
SK-N-MC CTRP2 6.0812 11.1787 2.7926 7.627
Hs 822.T CTRP2 6.3539 7.1574 4.7859 0.0669
MG-63 GDSC1; GDSC2; CTRP2 7.1431 15.0555 1.6617 10.4362
TC71 CTRP2 7.3073 16.3222 1.1621 12.0319
HOS GDSC1; GDSC2; CTRP2 7.3131 8.7347 4.5863 0.1274
SW1353 CTRP2 7.4534 8.7505 4.6303 0.0659
MHH-ES-1 GDSC1; GDSC2; CTRP2 7.9718 18.4133 0.6145 12.9536
⏷ Show the Full List of 45 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 217 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 1.0591 9.6083 -1.0468 33.0223
MEC1 CTRP2 3.1938 6.5407 2.4841 14.9644
JM1 GDSC1; GDSC2; CTRP2 -1.364 1.183 -1.3732 42.7197
Mino CTRP2 -12.701 -5.1913 -12.7388 91.6783
Kasumi-2 CTRP2 -6.1693 -2.5611 -6.1729 73.6857
Ri-1 CTRP2 -6.1 -2.3312 -6.1051 73.1216
ALL-PO GDSC1; GDSC2 -6.0755 -1.6904 -6.1111 73.1992
SUP-B15 GDSC1; GDSC2 -5.546 -4.341 -5.546 72.1647
Loucy GDSC1; GDSC2 -5.4475 -3.6312 -5.4476 71.2776
SEM CTRP2 -5.2295 -2.657 -5.2298 68.3119
NKM-1 GDSC1; GDSC2 -5.2276 -3.0409 -5.228 69.3967
NU-DHL-1 CTRP2 -4.982 -1.8914 -4.9842 66.5374
LC4-1 GDSC1; GDSC2 -4.6114 -2.5255 -4.6119 64.4906
ME1 GDSC1; GDSC2 -4.5816 -3.1854 -4.5816 64.3191
MV4-11 GDSC1; GDSC2 -4.5351 -2.1923 -4.5386 60.6203
BV-173 GDSC1; GDSC2; CTRP2 -4.3663 -1.2899 -4.3696 62.5371
KY821 GDSC1; GDSC2 -4.3471 -2.2004 -4.3479 62.3494
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 -4.2788 -1.4985 -4.2804 62.024
EoL-1 GDSC1; GDSC2; CTRP2 -4.2264 -2.0881 -4.2265 61.7459
GDM-1 GDSC1; GDSC2; CTRP2; CTRP1 -4.1621 -1.6896 -4.1627 61.3315
SK-MM-2 GDSC1; GDSC2; CTRP2 -4.1313 -2.5492 -4.1313 56.0894
KE-37 GDSC1; GDSC2; CTRP2 -3.9881 -1.7561 -3.9884 60.1579
MOLM-6 CTRP2 -3.9779 -1.596 -3.9784 60.0807
RS4;11 GDSC1; GDSC2; CTRP2 -3.9539 -2.2612 -3.9541 54.7544
SUP-HD1 GDSC1; GDSC2; CTRP2 -3.9515 -1.077 -3.9542 59.8538
ATN-1 GDSC1; GDSC2 -3.8825 0.0245 -3.9433 58.0772
BALL-1 GDSC1; GDSC2 -3.8698 -2.5312 -3.8698 58.5302
ALL-SIL GDSC1; GDSC2; CTRP2 -3.7075 -1.8694 -3.7076 58.3035
KO52 CTRP2 -3.6861 -1.8086 -3.6862 58.1604
Kasumi-1 GDSC2; CTRP2 -3.5116 -1.3272 -3.5119 56.9923
KG-1 GDSC1; GDSC2 -3.5078 -0.7632 -3.5183 55.4997
MY-M12 GDSC1; GDSC2 -3.4883 -2.0723 -3.4895 45.0456
L-1236 GDSC1; GDSC2; CTRP2 -3.4249 -0.8589 -3.4265 56.4004
QIMR-WIL GDSC1; GDSC2 -3.4044 0.02 -3.579 44.6639
MHH-CALL-4 GDSC2; CTRP2 -3.1082 -1.2965 -3.1083 54.3127
OCI-AML-2 GDSC1; GDSC2; CTRP2 -3.1062 -0.5994 -3.108 54.2881
OCI-Ly19 GDSC1; GDSC2; CTRP2 -3.0626 -1.3564 -3.0626 54.0091
MHH-CALL-3 CTRP2 -2.9731 18.6318 -9.2061 51.2427
Karpas-620 GDSC1; GDSC2; CTRP2 -2.9506 -1.5427 -2.9506 53.2638
MOLT-4 GDSC1; GDSC2 -2.9026 -0.167 -2.9193 50.6505
DND-41 GDSC1; GDSC2; CTRP2 -2.8919 -0.6207 -2.8929 52.8686
KMS-12-BM GDSC2; CTRP2 -2.8558 -1.0532 -2.8559 52.6318
MOLT-13 GDSC1; GDSC2; CTRP2 -2.8518 0.092 -2.8591 52.586
P12-Ichikawa GDSC1; GDSC2; CTRP2 -2.8287 -1.4493 -2.8287 52.452
CCRF-CEM GDSC1; GDSC2 -2.7974 -0.5854 -2.802 49.8044
MOLT-16 GDSC1; GDSC2; CTRP2 -2.7208 0.9331 -2.7517 51.6949
HEL 92.1.7 CTRP2 -2.6956 0.507 -2.7099 51.5465
697 GDSC1; GDSC2; CTRP2 -2.6592 -1.121 -2.6592 51.3224
ML-2 GDSC1; GDSC2 -2.6523 0.4905 -2.6956 48.66
NU-DUL-1 GDSC1; GDSC2; CTRP2; CTRP1 -2.6386 0.9336 -2.6669 51.2083
KMS-34 CTRP2 -2.4805 -1.0077 -2.4805 50.1317
Karpas-45 GDSC1; GDSC2 -2.4374 -0.3797 -2.4414 46.8825
HDLM-2 GDSC1; GDSC2; CTRP2 -2.3994 0.9598 -2.4227 49.5978
OCI-Ly7 GDSC1; GDSC2 -2.3759 0.6248 -2.5889 34.8782
ROS-50 GDSC1; GDSC2 -2.3631 1.8452 -2.9315 36.2096
MOLT-3 CTRP2 -2.3182 -0.4338 -2.3186 49.0512
EM-2 GDSC1; GDSC2; CTRP2 -2.2834 -0.5241 -2.2836 48.819
SU-DHL-16 GDSC1; GDSC2 -2.2629 -1.0414 -2.266 32.759
RPMI-8226 GDSC1; GDSC2; CTRP2; CTRP1 -2.1419 0.7104 -2.152 47.9392
Karpas-231 GDSC1; GDSC2 -2.1291 -0.2664 -2.1318 44.3733
NALM-6 GDSC1; GDSC2; CTRP2 -2.1167 0.6977 -2.1263 47.7216
Reh GDSC1; GDSC2; CTRP2 -2.1001 -0.6952 -2.1001 47.5976
MOLM-13 GDSC1; GDSC2; CTRP2 -2.0424 0.9401 -2.057 47.2359
Peer CTRP2 -1.9985 -0.366 -1.9986 46.9209
M-07e CTRP2 -1.9206 1.0045 -1.9347 46.428
DoHH2 GDSC1; GDSC2; CTRP2 -1.8753 1.8859 -1.9344 46.1978
BE-13 GDSC1; GDSC2 -1.8713 -0.0993 -1.8739 42.276
Sc-1 GDSC1 -1.8649 -0.7958 -1.8676 35.8285
CML-T1 GDSC1; GDSC2; CTRP2 -1.846 0.2671 -1.8475 45.9086
OCI-Ly3 CTRP2 -1.8072 1.9368 -1.8672 45.7539
HAL-01 GDSC1; GDSC2 -1.7864 1.057 -1.8355 41.7358
NCO2 CTRP2 -1.7679 -0.0673 -1.7681 45.3852
BONNA-12 GDSC2 -1.7526 3.6697 -2.9967 33.3461
KOPN-8 GDSC1; GDSC2 -1.7032 2.974 -2.0712 41.898
OCI-AML-5 GDSC1; GDSC2; CTRP2 -1.6826 0.4817 -1.6847 44.8218
VAL GDSC1; GDSC2 -1.5742 -0.1053 -1.575 39.8514
PF-382 GDSC1; GDSC2; CTRP2 -1.5613 -0.0035 -1.5618 40.197
SET-2 CTRP2 -1.5502 0.2365 -1.5507 43.9354
SU-DHL-6 GDSC1; GDSC2; CTRP2 -1.4374 1.1867 -1.4478 43.2112
DB GDSC1; GDSC2 -1.3958 2.0345 -1.541 38.9016
TF-1 CTRP2 -1.3448 2.2685 -1.4111 42.731
RCH-ACV GDSC1; GDSC2; CTRP2 -1.3161 1.9719 -1.3582 42.4849
H9 GDSC1; GDSC2 -1.2968 1.5527 -1.3685 37.8577
HPB-ALL CTRP2 -1.2953 0.9773 -1.2998 42.2495
RC-K8 GDSC1; GDSC2 -1.1704 3.3031 -1.5755 37.9357
HL-60 GDSC1; GDSC2; CTRP2 -1.114 3.0809 -1.26 41.4012
KMOE-2 GDSC1; GDSC2 -1.0602 0.7723 -1.0689 35.6999
Granta-519 GDSC1; GDSC2; CTRP2 -1.0478 1.6338 -1.0643 40.6367
CMK GDSC1; CTRP2 -0.9449 1.939 -0.972 39.9831
RPMI-8402 GDSC1; GDSC2; CTRP2 -0.9298 2.0758 -0.9641 39.9036
L-428 GDSC1; GDSC2; CTRP2 -0.9144 1.7856 -0.9335 39.7567
SU-DHL-8 GDSC1; GDSC2; CTRP2 -0.891 1.8434 -0.9119 39.6069
WSU-DLCL2 GDSC1; GDSC2; CTRP2; CTRP1 -0.7373 2.3712 -0.7835 38.719
KMS-18 CTRP2 -0.6939 0.7091 -0.6941 38.2302
MM1.S GDSC1; GDSC2; CTRP2 -0.6857 1.1364 -0.6874 38.1802
Ramos.2G6.4C10 GDSC1; GDSC2 -0.6333 4.9191 -1.5161 35.3479
ARH-77 GDSC1; GDSC2 -0.5824 3.1609 -0.8961 33.0106
ST486 GDSC1; GDSC2; CTRP2 -0.5775 2.9818 -0.6753 37.7519
P30/OHK GDSC1; GDSC2 -0.549 2.5745 -0.7245 32.2096
RL GDSC1; GDSC2; CTRP2 -0.4768 1.8091 -0.487 36.8162
P31/FUJ GDSC1; GDSC2; CTRP2 -0.452 2.6813 -0.5112 36.8053
WSU-NHL GDSC1; GDSC2 -0.434 3.4179 -0.8036 35.7679
OCI-M1 GDSC1; GDSC2; CTRP2 -0.4335 1.1965 -0.4344 36.4975
TK [Human B-cell lymphoma] GDSC1; GDSC2 -0.4085 1.8529 -0.462 30.5792
JVM-2 GDSC1; GDSC2; CTRP2 -0.3656 4.0196 -0.7539 33.0204
RPMI-6666 GDSC1; GDSC2; CTRP2 -0.3503 3.3787 -0.4861 36.3626
MOLM-16 GDSC1; GDSC2; CTRP2; CTRP1 -0.2695 4.545 -0.6243 36.5193
VL51 GDSC1; GDSC2 -0.2566 2.9051 -0.478 30.0326
MEG-01 GDSC1; GDSC2 -0.1891 3.0317 -0.4346 29.586
SU-DHL-4 GDSC1; GDSC2; CTRP2; CTRP1 -0.1862 3.1727 -0.2821 35.2169
AML-193 CTRP2 -0.1429 4.4122 -0.4574 35.5253
KMS-28BM CTRP2 -0.0847 5.5592 -0.7018 35.988
JJN-3 GDSC1; GDSC2; CTRP2 0.0752 2.8609 0.0258 33.2686
JVM-3 GDSC1; GDSC2; CTRP2 0.1504 5.6177 -0.4635 34.4935
LAMA-84 GDSC1; GDSC2; CTRP2 0.2017 3.131 0.0645 28.1463
Farage GDSC1; GDSC2 0.2154 5.1293 -1.7502 19.4697
SUP-M2 GDSC1; GDSC2; CTRP2 0.2728 4.3398 0.0111 32.643
RPMI-8866 GDSC1; GDSC2 0.3851 5.2757 -0.5681 27.9238
NK-92MI GDSC2 0.3996 3.125 -0.5966 11.9948
HEL GDSC1; GDSC2; CTRP2 0.4241 5.3202 -0.304 28.7199
JURL-MK1 GDSC1; GDSC2; CTRP2 0.4452 2.6821 0.4232 30.714
PL21 CTRP2; CTRP1 0.5394 2.2854 0.5341 30.098
Jurkat GDSC1; GDSC2; CTRP2 0.8052 4.3613 0.4271 24.7645
Karpas-422 GDSC1; GDSC2; CTRP2 0.8566 4.2692 0.66 28.5656
Pfeiffer CTRP2 0.9035 4.112 0.7415 28.1362
KMS-11 GDSC1; GDSC2; CTRP2; CTRP1 0.9339 5.4177 0.4542 29.0798
KCL-22 GDSC1; GDSC2; CTRP2 0.9352 3.2674 0.8919 27.5213
F-36P CTRP2 1.0567 7.0408 0.0213 30.0271
Mono-Mac-1 CTRP2 1.1721 6.931 0.1866 29.14
SUP-T1 GDSC1; GDSC2; CTRP2 1.2584 6.1843 0.5535 27.6553
L-540 GDSC1; GDSC2; CTRP2 1.2607 7.2239 0.1673 28.9275
YT GDSC1; GDSC2 1.3167 2.7202 1.2636 16.5407
NOMO-1 GDSC1; GDSC2; CTRP2; CTRP1 1.5193 7.2381 0.4409 27.3075
Ku812 GDSC1; GDSC2; CTRP2; CTRP1 1.5233 5.8899 0.9452 25.5544
CESS GDSC1; GDSC2 1.6675 4.3371 1.1648 15.7192
SUP-T11 CTRP2 1.6797 4.285 1.5483 22.8654
Hs 445 GDSC2 1.7396 4.4251 1.2056 15.285
IM-9 GDSC1; GDSC2 1.9032 3.4511 1.7365 12.2651
HuT 78 CTRP2 1.9972 5.0556 1.7158 21.2836
SUP-B8 GDSC1; GDSC2 2.0548 5.2155 -0.3067 5.6557
MLMA GDSC1; GDSC2 2.1252 5.4032 1.1702 14.2302
KYO-1 CTRP2 2.1294 4.0165 2.0736 19.6089
EB1 CTRP2 2.1939 5.3418 1.8475 20.2119
HC-1 GDSC1; GDSC2 2.3573 3.4896 2.2191 8.4509
KMS-20 CTRP2 2.3659 8.789 0.6476 24.1132
OCI-Ly10 CTRP2; CTRP1 2.4052 6.0121 1.8562 19.6355
EB2 GDSC1; GDSC2 2.4261 3.8736 2.1532 8.5157
OPM-2 GDSC1; GDSC2; CTRP2 2.4918 5.8396 2.0071 18.7453
EJM GDSC1; GDSC2; CTRP2; CTRP1 2.5055 7.2315 1.4809 20.7632
A3/Kawakami GDSC1; GDSC2; CTRP2 2.5055 3.4318 2.5035 16.921
U-937 CTRP2; CTRP1 2.5094 6.7826 1.6707 20.037
P32/ISH GDSC1; GDSC2 2.5155 3.7778 2.2859 7.5904
BL-41 GDSC1; GDSC2 2.575 3.3771 2.4911 6.4401
BL-70 CTRP2; CTRP1 2.5841 3.4372 2.5827 16.4761
LP-1 GDSC1; GDSC2; CTRP2; CTRP1 2.6008 5.4648 2.2555 17.5848
MC116 GDSC1; GDSC2; CTRP2; CTRP1 2.6112 3.9538 2.5894 16.3643
Hs 611.T CTRP2 2.6584 7.5628 1.4915 20.2335
SKM-1 GDSC1; GDSC2; CTRP2; CTRP1 2.7077 5.0716 2.4895 16.4117
CTV-1 GDSC1; GDSC2 2.8323 4.5577 2.2602 6.7278
WIL2 NS GDSC1; GDSC2 2.8504 4.5686 2.2723 6.6155
HH [Human lymphoma] GDSC1; GDSC2 2.8649 7.0874 1.046 12.7779
HT GDSC1; GDSC2; CTRP2; CTRP1 2.8963 9.6805 0.7673 22.3599
DEL GDSC1; GDSC2; CTRP2 2.8984 5.8474 2.4428 15.9423
BC-1 GDSC1; GDSC2 2.9666 6.2735 1.5405 10.0172
PL-21 GDSC1; GDSC2 3.015 10.4426 -2.1656 13.9213
Karpas-1106P GDSC1; GDSC2 3.0304 5.1533 2.1533 6.7256
BC-3 GDSC2 3.0967 4.7432 0.4581 0.4447
SU-DHL-5 GDSC1; GDSC2; CTRP1 3.1287 4.3597 3.0941 13.8888
GR-ST GDSC1; GDSC2 3.1527 5.7517 1.9633 7.3859
CRO-AP2 GDSC1; GDSC2 3.2538 10.2603 -1.9132 12.1439
Daudi GDSC1; GDSC2; CTRP2 3.2586 6.1881 2.6968 13.9641
SIG-M5 GDSC2; CTRP2 3.3488 12.3682 -0.1114 24.136
JSC-1 GDSC1; GDSC2 3.3969 4.6795 2.7046 2.9974
DG-75 GDSC1; GDSC2 3.5532 6.1661 2.0877 5.8127
GA-10 GDSC1; GDSC2; CTRP2 3.7033 5.4135 3.4657 9.7862
SCC-3 GDSC2 3.7235 6.6339 1.9876 5.9609
MN-60 GDSC1; GDSC2 3.7841 5.6396 2.522 3.1374
CTB-1 GDSC1; GDSC2 3.8385 7.7722 -0.4155 3.3338
Mono-Mac-6 GDSC1; GDSC2; CTRP2 3.8755 10.901 1.0928 18.7337
OCI-AML-3 GDSC1; GDSC2; CTRP2; CTRP1 4.0325 5.1397 3.9156 7.2428
HD-MY-Z CTRP2 4.1098 6.3002 3.5331 8.4215
MOLP-2 CTRP2 4.1593 8.7954 2.3884 12.9814
Jiyoye GDSC1; GDSC2 4.4818 10.5752 0.6107 11.2383
KMS-21-BM CTRP2 4.5879 11.7118 1.323 16.3052
Namalwa GDSC1; GDSC2; CTRP2 4.6654 6.6109 3.9266 5.4852
CA46 GDSC1; GDSC2; CTRP2 4.6851 7.0733 3.7169 6.3146
P3HR-1 CTRP2; CTRP1 4.7195 5.8304 4.3635 3.6481
A4/Fukuda GDSC1; GDSC2; CTRP2 4.9843 11.6844 1.6742 14.1323
AMO1 GDSC1; GDSC2; CTRP2; CTRP1 5.0874 5.9467 4.6385 1.711
MHH-CALL-2 GDSC1; GDSC2 5.2245 13.2654 -0.1672 13.2874
MHH-PREB-1 GDSC1; GDSC2 5.3366 7.0664 2.7463 0.4776
U-698-M GDSC1; GDSC2 5.5669 7.5308 2.6669 0.5674
KMS-26 CTRP2 5.5851 7.122 4.4143 1.7686
NCI-H929 GDSC1; GDSC2; CTRP2 5.688 7.7079 3.373 1.057
TUR GDSC1; GDSC2 5.7131 9.3052 2.0096 2.7703
U266B1 GDSC1; GDSC2; CTRP2 5.7776 12.6345 1.8417 11.9781
EHEB GDSC1; CTRP2 5.9578 16.2942 0.1614 17.7843
Ci-1 CTRP2 6.0541 14.4086 1.1749 14.0455
THP-1 GDSC1; GDSC2; CTRP2; CTRP1 6.1246 11.6101 2.6234 8.3206
KHM-1B CTRP2 6.1648 10.3274 3.2683 5.5578
K-562 GDSC1; GDSC2; CTRP2 6.3171 10.4304 3.324 5.1106
Raji GDSC1; GDSC2; CTRP2 6.5978 8.0566 4.5529 0.407
NB4 GDSC1; GDSC2; CTRP2 6.6295 8.6751 4.3179 1.0383
SR GDSC1; GDSC2; CTRP2 6.7371 15.9974 0.9066 13.8575
KE-97 CTRP2; CTRP1 6.7785 7.9742 4.6703 0.1505
MOTN-1 CTRP2 6.8366 12.151 2.8509 6.2652
SU-DHL-10 GDSC1; GDSC2; CTRP2 6.8406 7.6959 4.7727 0.0256
Ki-JK CTRP2 6.9042 15.7214 1.1654 12.6508
Toledo CTRP2 6.932 22.2312 -2.031 22.3649
JeKo-1 GDSC1; GDSC2; CTRP2 6.978 17.3636 0.4126 15.1784
KMM-1 CTRP2 6.9808 11.1635 3.4085 3.9129
L-363 GDSC1; GDSC2; CTRP2 7.0949 8.3764 4.6315 0.1138
Karpas-299 GDSC1; GDSC2; CTRP2 7.2925 8.6823 4.597 0.1188
KM-H2 GDSC1; GDSC2; CTRP2 7.4654 13.7319 1.7046 5.372
REC-1 CTRP2 7.9476 9.82 4.4397 0.1851
MOLP-8 GDSC1; GDSC2; CTRP2 8.4736 16.1734 2.0119 7.3285
SU-DHL-1 GDSC2; CTRP2 8.9892 17.0454 1.9258 7.0285
⏷ Show the Full List of 217 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 2.3146 4.0366 -0.5634 0.3999
TE15 CTRP2 7.7046 10.2892 4.1693 0.7768
T.T GDSC1; GDSC2 1.0995 3.9872 0.687 19.8924
TE-8 GDSC1; GDSC2 2.4994 7.4478 -0.0947 12.9376
TE-4 GDSC1; GDSC2; CTRP2 3.3673 8.4074 0.8169 11.7443
KYSE-450 GDSC1; GDSC2; CTRP2; CTRP1 3.8676 5.1448 3.7344 8.3974
KYSE-410 GDSC1; GDSC2; CTRP2; CTRP1 3.8887 6.975 3.01 11.1622
TE-6 GDSC1; GDSC2; CTRP2 5.2915 9.8272 1.5275 5.0519
TE-15 GDSC1; GDSC2 5.3881 8.5406 2.1668 2.4823
TE-5 GDSC1; GDSC2; CTRP2 5.4861 11.2013 2.3258 10.557
KYSE-270 GDSC1; GDSC2 5.5626 8.5613 2.2498 1.9658
KYSE-510 GDSC1; GDSC2; CTRP2 6.1831 12.1965 2.3673 9.1869
TE-9 GDSC1; GDSC2; CTRP2 6.2768 7.8791 3.5641 0.2516
KYSE-70 GDSC1; GDSC2; CTRP2 6.4703 14.1302 1.6281 11.624
TE-10 GDSC1; GDSC2; CTRP2 6.579 8.3423 3.5134 0.2505
OE19 GDSC1; GDSC2; CTRP2 6.7162 8.1657 4.5615 0.3355
KYSE-520 GDSC1; GDSC2; CTRP2 6.9428 12.969 2.5308 7.3762
OE33 GDSC1; GDSC2; CTRP2 7.0311 8.7548 4.4701 0.3996
EC-GI-10 GDSC1; GDSC2; CTRP2 7.0889 13.7015 2.2785 8.1529
KYSE-150 GDSC1; GDSC2; CTRP2 7.5007 13.5257 2.6343 6.2235
TE-1 GDSC1; GDSC2; CTRP2 7.6883 9.3697 4.502 0.1586
COLO 680N GDSC1; GDSC2; CTRP2 7.8167 14.0479 2.5899 5.9977
TE-14 CTRP2 7.976 9.8509 4.4393 0.1802
TE-11 GDSC1; GDSC2; CTRP2 8.0662 15.7806 1.9374 8.1121
KYSE-30 CTRP2 8.3327 15.5928 2.1937 6.8379
OE21 GDSC1; GDSC2; CTRP2 8.6248 16.3493 2.024 7.1035
KYSE-140 GDSC1; GDSC2; CTRP2; CTRP1 9.4194 19.1752 1.2191 9.0276
KYSE-180 GDSC1; GDSC2; CTRP2 11.4126 23.1125 0.6037 8.7388
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 41 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 7.1874 8.496 4.6235 0.1071
HPAF-II GDSC1; GDSC2; CTRP2 -0.4528 1.5924 -0.4578 36.6395
Capan-2 GDSC1; GDSC2; CTRP2; CTRP1 0.3517 3.4152 0.2595 31.6359
KP-2 GDSC1; GDSC2; CTRP2 1.6231 4.1095 1.518 23.1512
PL4 GDSC1; GDSC2 1.7587 4.5719 1.165 15.414
HuP-T4 GDSC1; GDSC2; CTRP2; CTRP1 2.0147 5.7125 1.5377 21.9514
SU.86.86 GDSC1; GDSC2; CTRP2 2.2794 4.4383 1.7625 10.0438
HPAC GDSC1; GDSC2; CTRP2; CTRP1 2.7141 11.0757 -0.073 25.6537
PaTu 8988s CTRP2 2.8657 5.1906 2.6252 15.3614
KP-3 GDSC1; GDSC2; CTRP2; CTRP1 2.8954 5.4806 2.5706 15.5546
Panc 10.05 GDSC1; GDSC2; CTRP2; CTRP1 2.9386 5.7714 2.5175 15.6269
Panc 03.27 GDSC1; GDSC2; CTRP2; CTRP1 3.2525 7.2565 2.2409 15.8421
KP-4 GDSC1; GDSC2; CTRP2 3.3042 4.2417 3.29 11.6413
AsPC-1 GDSC1; GDSC2; CTRP2 3.5434 8.7982 1.8061 16.7596
KP-1N GDSC1; GDSC2 3.5538 5.4625 2.4382 4.0197
SUIT-2 GDSC1; GDSC2; CTRP2; CTRP1 3.7881 5.0519 3.674 8.8565
Panc 08.13 GDSC1; GDSC2; CTRP2 4.2495 10.8866 1.437 16.5897
Capan-1 GDSC1; GDSC2; CTRP2 4.3646 8.2372 2.8512 10.6172
MZ-PC-1 GDSC1; GDSC2 4.4694 7.1029 2.2807 3.1693
PaTu 8902 GDSC1; GDSC2; CTRP2; CTRP1 4.5958 6.3436 3.999 5.4324
MIA PaCa-2 GDSC1; GDSC2; CTRP2 4.7435 5.3712 4.5923 2.5741
BxPC-3 GDSC1; GDSC2; CTRP2 5.2507 13.5268 0.9739 16.2779
SNU-410 CTRP2 5.585 10.5202 2.743 8.6645
SW1990 GDSC1; GDSC2; CTRP2 5.9363 12.9608 1.8027 11.8519
DAN-G GDSC1; GDSC2; CTRP2 6.021 12.2092 2.2398 9.9688
PANC-1 CTRP2 6.4225 9.2825 3.934 2.5824
PSN1 GDSC1; GDSC2; CTRP2 6.5034 16.025 0.7175 14.92
PK-45H CTRP2 6.8213 11.8793 2.9702 5.816
Hs 766T GDSC1; GDSC2; CTRP2 6.8719 17.1049 0.4612 15.1884
PaTu 8988t GDSC1; GDSC2; CTRP2 6.9468 8.1019 4.673 0.0927
L3.3 CTRP2 7.1172 8.5695 4.572 0.1873
Panc 02.03 GDSC1; GDSC2; CTRP2 7.2142 14.4478 2.0051 9.0265
QGP-1 GDSC1; GDSC2; CTRP2; CTRP1 7.2397 14.1439 2.1802 8.3862
HuP-T3 GDSC1; GDSC2; CTRP2 7.2973 11.1135 3.6181 2.7952
YAPC GDSC1; GDSC2; CTRP2 7.4702 8.8058 4.6175 0.0742
SNU-213 CTRP2 7.4823 13.7903 2.4979 6.7675
Panc 04.03 GDSC1; GDSC2; CTRP2 7.6458 10.7958 3.9384 1.4415
TCC-Pan2 CTRP2 8.2996 14.9026 2.4915 5.7913
PK-59 CTRP2 8.8842 17.6986 1.5593 8.4425
Panc 05.04 CTRP2 8.9007 17.2542 1.7756 7.6609
CFPAC-1 GDSC1; GDSC2; CTRP2; CTRP1 8.955 16.0471 2.3718 5.56
⏷ Show the Full List of 41 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 76 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 9.6282 25.2243 -1.5281 17.0317
COLO 783 GDSC1; GDSC2 -1.4738 2.633 -2.2716 28.914
CJM [Human melanoma] CTRP2 -0.2166 4.8319 -0.6405 36.3084
Hs 940.T GDSC1; GDSC2; CTRP2 0.1826 3.9831 -0.0139 33.0304
A-388 GDSC1; GDSC2 0.2766 5.595 -1.9251 20.2087
COLO 792 GDSC1; GDSC2; CTRP2 0.3412 3.571 0.226 31.7157
Malme-3M CTRP2 0.4877 13.6537 -3.4675 39.2396
WM278 GDSC1; GDSC2 1 4.9946 0.1944 22.4746
Hs 852.T CTRP2; CTRP1 1.0978 9.0138 -0.7413 32.1698
WM115 GDSC1; GDSC2; CTRP2 1.3237 4.6764 1.0781 25.6328
SK-MEL-1 GDSC1; GDSC2; CTRP2; CTRP1 1.4515 5.8866 0.8685 26.0423
VMRC-MELG GDSC2 1.6508 4.518 -0.2505 6.2106
WM983B CTRP2 1.7713 5.6307 1.2966 23.4791
A-431 GDSC1; GDSC2 2.0015 6.4812 -0.9574 9.6735
CHL-1 GDSC1; GDSC2 2.0051 3.8048 1.7291 11.9349
MMAc-SF GDSC1; GDSC2 2.0436 9.4455 -2.3877 17.3366
LB373-MEL-D GDSC1; GDSC2 2.1783 3.6084 0.4977 0.9896
Hs 938.T GDSC1; GDSC2 2.2321 7.9165 -1.4929 12.2018
SK-MEL-31 GDSC1; GDSC2; CTRP2 2.4296 10.3271 -0.0006 26.1088
CP50-MEL-B GDSC1; GDSC2 2.4457 7.1458 -0.9675 8.7252
G-mel GDSC1; GDSC2 2.5345 12.463 -3.5083 20.956
GAK GDSC1; GDSC2 2.6602 3.4718 2.5539 5.8492
RPMI-7951 GDSC1; GDSC2; CTRP2 2.6847 8.041 1.3071 20.8592
CP66-MEL GDSC1; GDSC2 2.7298 4.3198 0.466 0.6364
WM1552C GDSC1; GDSC2 2.8619 6.6753 1.248 11.7711
A101D GDSC1; GDSC2; CTRP2 2.9595 7.2534 1.9362 17.7223
IST-MEL1 GDSC1; GDSC2 3.0621 4.3908 2.558 4.5814
LB2518-MEL GDSC1; GDSC2 3.0827 10.1538 -1.979 12.8419
MZ-MEL-7 GDSC1; GDSC2 3.1516 4.5628 0.5436 0.2223
IGR-37 GDSC1; GDSC2; CTRP2 3.251 4.6696 3.1753 12.2075
MeWo GDSC1; GDSC2; CTRP2 3.2535 6.174 2.6971 13.9766
WM266-4 CTRP2 3.3301 4.1906 3.3204 11.4535
COLO 679 GDSC1; GDSC2 3.3692 4.6714 2.6861 3.1551
SH-4 GDSC1; GDSC2 3.5736 5.3093 2.5294 3.5136
WM88 CTRP2 3.7388 9.8162 1.4989 17.5011
DJM-1 GDSC1; GDSC2 3.7869 12.8817 -2.8093 15.2535
G-361 GDSC1; GDSC2; CTRP2; CTRP1 4.0342 9.015 2.1732 14.2189
MZ-MEL-2 GDSC1; GDSC2 4.06 12.8136 -2.5925 13.7438
WT2-iPS GDSC1; GDSC2; CTRP2 4.204 9.1635 2.2485 13.4535
RVH-421 GDSC1; GDSC2; CTRP2 4.3995 4.9898 4.3548 4.4514
HT-144 GDSC1; GDSC2; CTRP2 4.4361 9.286 2.3975 12.337
451Lu GDSC1; GDSC2 4.5092 13.8447 -2.7861 13.7306
COLO 741 CTRP2; CTRP1 4.9329 19.4588 -2.2463 26.5263
HMV-II GDSC1; GDSC2 5.0292 7.4508 2.4467 1.7279
M14 GDSC1; GDSC2 5.1394 8.1463 2.2031 2.6179
SK-MEL-28 GDSC1; GDSC2; CTRP2; CTRP1 5.2838 6.6006 4.4665 2.0861
IGR-1 GDSC1; GDSC2; CTRP2 5.4279 13.9598 0.9021 16.1989
WM35 GDSC1; GDSC2 5.842 10.9739 1.3364 5.5289
A-375 GDSC1; GDSC2; CTRP2; CTRP1 6.3644 8.1352 4.4242 0.9686
Hs 839.T CTRP2 6.461 7.4462 4.7242 0.1242
SK-MEL-30 GDSC1; GDSC2; CTRP2 6.4624 7.7136 4.6266 0.3021
A2058 GDSC1; GDSC2; CTRP2 6.4748 7.4111 4.7417 0.0972
SK-MEL-5 GDSC1; GDSC2; CTRP2; CTRP1 6.4882 8.5712 4.3022 1.2621
Hs 688(A).T CTRP2 6.5443 7.6309 4.6898 0.155
IGR-39 CTRP2 6.779 9.362 4.1023 1.6128
UACC-62 GDSC1; GDSC2; CTRP2 6.7808 7.7902 4.7207 0.0691
SK-MEL-2 GDSC1; GDSC2; CTRP2 6.8212 13.3225 2.2763 8.5528
COLO 829 GDSC1; GDSC2; CTRP2 6.9394 9.5018 4.1265 1.3968
IPC-298 GDSC1; GDSC2; CTRP2 6.9559 8.3512 4.5888 0.2035
HMCB CTRP2 6.9607 10.692 3.6127 3.1706
WM1799 CTRP2 7.0677 8.4393 4.5996 0.1595
UACC-257 GDSC1; GDSC2; CTRP2 7.0981 8.6299 4.5431 0.2379
MDA-MB-435S CTRP2 7.2184 13.1653 2.6214 6.6421
SK-MEL-3 GDSC1; GDSC2; CTRP2 7.2254 9.4757 4.2754 0.7665
LOX-IMVI GDSC1; GDSC2; CTRP2 7.3908 12.4293 3.0759 4.6834
K029AX CTRP2 7.5938 8.9992 4.5951 0.0784
COLO 800 GDSC1; GDSC2; CTRP2 7.7351 15.3628 1.9185 8.6224
Hs 895.T CTRP2 7.7781 8.9629 4.669 0.0225
Hs 294T CTRP2 7.8911 13.061 3.0864 4.0835
Hs 936.T CTRP2; CTRP1 7.9384 14.1131 2.6471 5.7044
WM793 GDSC1; GDSC2; CTRP2 8.0076 14.0787 2.6928 5.3898
SK-MEL-24 GDSC1; GDSC2; CTRP2 8.0076 14.2729 2.6035 5.7189
Hs 944.T CTRP2; CTRP1 8.0489 20.3598 -0.2655 15.7423
Mel JuSo GDSC1; GDSC2; CTRP2 8.5487 16.5764 1.8714 7.7436
Mel Ho GDSC1; GDSC2; CTRP2 10.2477 21.11 0.8225 9.3135
EquiPSC Line K2 GDSC1; GDSC2 2.0772 4.8704 -0.1279 4.5474
⏷ Show the Full List of 76 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACP4 C GDSC1; GDSC2 -0.2666 4.4783 -0.9616 31.9503
FLO-1 GDSC1; GDSC2 1.2347 3.9615 0.8422 18.7077
KYSE-50 GDSC1; GDSC2 2.3402 4.2459 1.9086 9.9624
HCE-4 GDSC1; GDSC2 2.4764 4.6684 0.201 2.0532
KYAE-1 GDSC1; GDSC2 2.5384 6.718 0.9337 14.2089
ESO-26 GDSC1; GDSC2 2.8906 5.4457 1.8822 8.4767
KYSE-220 GDSC1; GDSC2 3.1182 4.971 2.322 5.6358
SK-GT-4 GDSC1; GDSC2 3.9755 9.713 0.6533 12.0884
TE-12 GDSC1; GDSC2 4.639 13.475 -2.5283 12.363
ESO-51 GDSC1; GDSC2 4.8498 7.3794 2.3806 2.2042
OACM5.1 C GDSC1; GDSC2 5.1491 9.7113 1.4914 5.8445
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1; GDSC2; CTRP2 7.049 11.1079 3.4756 3.5807
Cancer Drug Sensitivity Data Curated from 35 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-N-RT-BM-1 GDSC2 -5.7397 -2.4721 -5.7714 66.1781
CHP-126 GDSC1; GDSC2; CTRP2 -4.9536 -2.171 -4.9546 66.4518
TGW GDSC1; GDSC2 -4.6261 -2.3962 -4.627 64.5763
SJNB-17 GDSC1; GDSC2 -3.7702 -1.5606 -3.7875 47.8991
NB(TU)1 GDSC1; GDSC2 -2.9727 0.4922 -3.0299 51.181
IMR-32 CTRP2 -2.7425 1.8428 -2.8402 51.7771
SJNB-12 GDSC1; GDSC2 -2.7134 0.5293 -2.7621 49.147
NH-12 GDSC1; GDSC2 -2.6513 2.4241 -2.9755 48.796
SK-N-BE(2) CTRP2 -2.5275 4.6837 -3.1234 50.3632
SJNB-13 GDSC1; GDSC2 -2.0897 0.2363 -2.122 39.2162
SJNB-14 GDSC1; GDSC2 -1.9967 0.5299 -2.019 43.3563
CHP-134 GDSC1; GDSC2 -1.5721 0.4752 -1.5818 39.8683
KP-N-YS GDSC1; GDSC2 -0.0458 3.9105 -1.3979 18.3964
NB69 GDSC1; GDSC2 -0.0283 4.206 -0.6088 29.6549
SK-N-DZ GDSC1; GDSC2; CTRP2 0.4242 2.8061 0.3941 30.8809
LA-N-6 GDSC1; GDSC2 0.4805 7.4973 -2.6911 23.3029
SJNB-6 GDSC1; GDSC2 0.8315 3.0139 -0.1506 7.7898
SiMa GDSC1; GDSC2 1.1712 4.7845 0.4603 20.6792
IMR-5 GDSC1; GDSC2 1.3188 3.8758 0.963 17.8598
SK-N-MC-IXC GDSC1; GDSC2 1.3617 3.2453 0.1627 4.3377
SJNB-5 GDSC1; GDSC2 1.5617 8.4698 -2.2777 18.0864
Kelly GDSC1; GDSC2; CTRP2 1.8087 5.4773 1.3861 23.0437
KP-N-YN GDSC1; GDSC2; CTRP2 2.2768 8.4375 0.7151 24.1197
SJNB-10 GDSC1; GDSC2 2.5834 5.5354 1.5524 10.9902
SK-N-BE(2)-M17 GDSC1; GDSC2 2.7767 4.392 2.2847 6.7684
CHP-212 GDSC1; GDSC2; CTRP2 2.8059 10.3978 0.3317 24.0355
SJNB-7 GDSC1; GDSC2 3.0242 3.8255 2.7931 3.51
GOTO GDSC1; GDSC2 3.5204 8.544 0.8744 12.029
GI-ME-N GDSC1; GDSC2 3.645 5.218 2.6278 2.8709
SK-N-SH GDSC1; GDSC2; CTRP2 4.1899 11.118 1.269 17.3649
SK-N-FI GDSC1; GDSC2; CTRP2 4.7199 10.8033 1.8902 13.8064
MHH-NB-11 GDSC1; GDSC2; CTRP2 4.7313 13.248 0.6788 18.3875
SK-N-AS GDSC1; GDSC2; CTRP2 6.9788 8.7482 4.4506 0.4648
KP-N-SI9s CTRP2 7.0867 8.3199 4.6481 0.097
NB1 GDSC1; GDSC2; CTRP2 8.028 13.4111 3.0082 4.22
⏷ Show the Full List of 35 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-245 CTRP2 -0.2695 5.7738 -0.9693 37.3492
SNU-1079 CTRP2 1.2113 11.3295 -1.6712 34.0214
SNU-869 CTRP2 2.9534 6.5809 2.2154 16.6568
HuCC-T1 GDSC1; GDSC2; CTRP2 4.2783 6.3637 3.673 7.4362
SNU-308 CTRP2 5.3419 11.2618 1.4844 9.2754
SNU-1196 CTRP2 7.3098 8.8117 4.5583 0.1626
SNU-478 CTRP2 7.5505 9.0023 4.579 0.098
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 87 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MDA-MB-330 GDSC1; GDSC2 -3.8042 1.1212 -3.9835 57.0022
HCC1500 GDSC1; GDSC2; CTRP2 -2.9759 0.7649 -3.0062 53.3484
HCC1569 GDSC1; GDSC2 -2.4473 1.7022 -2.6174 47.1823
COLO 824 GDSC1; GDSC2 -2.1545 0.0636 -2.1633 44.5974
DU4475 GDSC1; GDSC2; CTRP2 -1.1704 4.5768 -1.6162 42.3587
HCC2157 GDSC1; GDSC2 -0.0869 6.2682 -1.4741 38.0866
CAL-120 GDSC1; GDSC2; CTRP2 0.1485 2.6827 0.1159 32.7252
HCC38 GDSC1; GDSC2; CTRP2 0.1705 2.8886 0.1233 32.627
MDA-MB-415 GDSC1; GDSC2 0.4478 3.7688 0.0528 25.0794
OCUB-M GDSC1; GDSC2 0.6814 4.5299 0.0392 27.1393
CAL-148 GDSC2; CTRP2 1.2063 4.8581 0.7034 22.4116
HDQ-P1 GDSC1; GDSC2; CTRP2 1.4673 7.242 0.3794 27.6029
EFM-19 GDSC1; GDSC2 1.7029 5.6808 0.6209 18.1875
HCC1428 GDSC1; GDSC2; CTRP2 1.8657 6.056 1.2546 23.3494
MDA-MB-231 GDSC1; GDSC2; CTRP2 1.8907 5.2947 1.5312 22.2723
UACC-812 GDSC2 1.9411 7.3223 0.08 19.9866
MFM-223 GDSC1; GDSC2 2.0031 4.7696 1.3337 13.8139
Hs 578T GDSC1; GDSC2; CTRP2 2.2753 8.3827 0.7381 24.0426
MDA-MB-157 GDSC1; GDSC2; CTRP2 2.2787 4.086 2.2236 18.612
Evsa-T GDSC1; GDSC2 2.4052 4.1508 2.0167 9.2335
MDA-MB-175-VII GDSC1; GDSC2 2.4701 4.3644 1.9903 9.1537
MRK-nu-1 GDSC1; GDSC2 2.6432 3.453 2.5417 5.9655
MDA-MB-468 GDSC1; GDSC2; CTRP2 2.7551 6.7205 1.9496 18.2212
CAL-85-1 GDSC1; GDSC2; CTRP2 2.8092 4.93 2.6353 15.4965
MDA-MB-361 GDSC1; GDSC2; CTRP2 2.8384 8.0303 1.4676 19.8463
UACC-893 GDSC1; GDSC2 3.0838 6.2249 1.6675 9.0715
HCC1599 GDSC2 3.1395 5.5325 2.0612 6.9172
HCC1143 GDSC1; GDSC2; CTRP2 3.1827 9.6851 1.0351 20.5967
MDA-MB-453 GDSC1; GDSC2; CTRP2 3.3064 5.1644 3.1136 12.2575
MDA-MB-436 GDSC1; GDSC2 3.3505 5.5683 2.2225 5.5785
HCC1419 GDSC1; GDSC2; CTRP2 3.4394 6.8519 2.6047 13.8406
HCC70 GDSC1; GDSC2 3.5794 6.0992 2.1416 5.4802
YMB-1-E GDSC2 3.5965 5.5476 0.361 0.4662
BT-483 GDSC1; GDSC2 4.2436 11.4674 -0.0105 14.5813
HCC1937 GDSC1; GDSC2; CTRP2 4.3112 10.8079 1.5309 16.0903
HCC1187 GDSC1; GDSC2 4.4647 9.1522 1.2956 7.9678
Hs 578Bst CTRP2 4.5043 5.0903 4.4418 3.8183
BT-20 GDSC1; GDSC2; CTRP2 4.7048 10.9875 1.7853 14.2566
AU565 GDSC1; GDSC2; CTRP2 5.5695 11.502 2.2421 10.7468
MCF-7 GDSC1; GDSC2; CTRP2; CTRP1 5.6754 11.2849 2.4435 9.8129
HCC202 GDSC1; GDSC2; CTRP2 5.8484 15.2252 0.6076 16.464
HCC1395 GDSC1; GDSC2; CTRP2 6.1968 11.4389 1.9858 5.8508
JIMT-1 GDSC1; GDSC2; CTRP2 6.247 13.3253 1.8585 11.1024
HMC-1-8 CTRP2 6.3284 8.3749 4.2883 1.3942
ZR-75-1 CTRP2 6.7411 8.3034 4.5196 0.4168
CAL-51 GDSC1; GDSC2; CTRP2 6.7664 8.7464 4.3555 0.8283
BT-474 GDSC1; GDSC2; CTRP2 6.9235 11.7151 3.1149 5.1133
ZR-75-30 GDSC1; GDSC2; CTRP2 7.0355 10.8264 3.5959 3.1499
CAMA-1 GDSC1; GDSC2; CTRP2 7.1485 13.6508 2.3433 7.8167
EFM-192A GDSC1; GDSC2; CTRP2 7.2419 13.2471 2.5981 6.7008
HCC1806 GDSC1; GDSC2; CTRP2 7.2431 15.2207 1.6517 10.324
SK-BR-3 CTRP2 7.3555 10.0632 4.0992 1.1709
HCC2218 GDSC1; GDSC2; CTRP2 7.5317 9.8492 4.2646 0.635
T-47D GDSC1; GDSC2; CTRP2 8.0853 15.805 1.9382 8.0844
HCC1954 GDSC1; GDSC2; CTRP2 8.1381 15.9827 1.8885 8.1986
BT-549 GDSC1; GDSC2; CTRP2 8.1623 18.1989 0.8492 11.8771
BT 239 CTRP2 -6.5929 -1.7553 -6.615 74.7333
BT 428 CTRP2 -0.091 2.6953 -0.1344 34.355
BT 245 CTRP2 0.2195 4.8228 -0.1623 33.3661
BT 498 CTRP2 1.2871 7.5873 0.0501 29.2198
BT 286 CTRP2 1.408 1.9996 1.408 24.2264
BT 248 CTRP2 1.4441 2.2749 1.4441 23.9856
BT 444 CTRP2 1.5128 2.1237 1.5128 23.528
BT147 CTRP2 1.5166 2.9339 1.5112 23.5205
BT 159 CTRP2 1.5549 13.7597 -2.4785 34.6896
BT 131 CTRP2 1.6812 2.4194 1.6811 22.4065
BT 172 CTRP2 1.6984 2.3322 1.6984 22.2913
BT 216 CTRP2 1.7888 2.8143 1.7879 21.6923
BT 422 CTRP2 2.022 3.1756 2.0187 20.1468
BT 145 CTRP2 2.8199 5.1065 2.5995 15.5928
BT 340 CTRP2 2.8749 8.1629 1.4443 19.8397
BT 139 CTRP2 2.9569 10.1121 0.6137 22.681
BT 179 CTRP2 2.9978 6.0773 2.4633 15.5831
BT 231 CTRP2 3.5037 12.0313 0.1964 22.7686
BT 187 CTRP2 5.4757 16.1479 -0.1521 19.7051
BT 320 CTRP2 6.3521 7.329 4.7246 0.1524
BT164 CTRP2 6.4992 7.5696 4.6946 0.1598
BT 112 CTRP2 6.5133 11.3569 3.0125 6.0789
BT 359 CTRP2 6.8373 8.2628 4.5746 0.2643
BT 440 CTRP2 6.8562 7.883 4.7157 0.0638
BT 504 CTRP2 7.1805 9.3865 4.2904 0.7528
BT 333 CTRP2 7.2418 10.1985 3.9862 1.5997
BT 328 CTRP2 7.3641 13.6787 2.4737 7.0168
BT 232 CTRP2 7.4188 9.8735 4.2052 0.8396
BT 330 CTRP2 7.6039 15.9641 1.5423 10.2031
BT 228 CTRP2 8.373 19.5584 0.3392 13.2892
BT 224 CTRP2 9.16 16.1852 2.4148 5.1387
⏷ Show the Full List of 87 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
YD-38 CTRP2 6.6235 7.8078 4.6566 0.1869
Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-466 CTRP2 -3.2598 -0.1063 -3.2686 55.2639
D283 Med GDSC1; GDSC2; CTRP2 -0.8375 3.063 -0.9623 39.5401
KNS-81-FD GDSC1; GDSC2 -0.4849 1.1342 -0.659 15.826
KG-1-C CTRP2 -0.0743 3.3131 -0.1819 34.4493
KNS-81 CTRP2 0.3041 2.2739 -0.8945 4.8384
AM-38 GDSC1; GDSC2; CTRP2 0.6601 6.5225 -0.2122 32.0229
D-247MG GDSC1; GDSC2 0.8606 6.2246 -1.7294 17.2568
KNS-60 CTRP2 1.0539 4.5822 -1.4834 6.7169
DBTRG-05MG GDSC1; GDSC2; CTRP2 1.2411 5.5471 0.7463 27.0473
Onda 11 GDSC1; GDSC2 1.4646 6.4814 -1.3638 13.4325
GI-1 GDSC1; GDSC2 1.6529 5.3147 0.7349 17.8041
SF539 GDSC1; GDSC2; CTRP2 2.0503 3.133 2.048 19.9548
H4 GDSC1; GDSC2 2.2163 3.2429 2.1359 9.3396
KINGS-1 GDSC1; GDSC2 2.5959 6.6167 1.0362 13.5424
D-566MG GDSC1; GDSC2 2.6903 8.8461 -1.6192 11.8312
M059J GDSC1; GDSC2 2.8859 5.7661 1.7198 9.3152
Daoy GDSC1; GDSC2; CTRP2 2.8964 3.7549 2.8932 14.3212
SF268 GDSC1; GDSC2; CTRP2 2.9008 4.3428 2.8526 14.4443
D-392MG GDSC1; GDSC2 2.926 4.4329 2.4098 5.7093
D-336MG GDSC1; GDSC2 2.939 6.4414 -0.325 4.1416
MOG-G-CCM GDSC1; GDSC2 2.9752 9.719 -0.17 18.2602
D-502MG GDSC1; GDSC2 2.9966 5.4072 0.1541 1.6531
MOG-G-UVW GDSC1; GDSC2 3.1256 4.8114 2.4079 5.1781
Onda 10 GDSC1; GDSC2 3.1959 8.5919 -1.1591 8.2756
GB-1 GDSC1; GDSC2; CTRP2 3.2458 5.7556 2.8499 13.4148
LN-405 GDSC1; GDSC2 3.2461 10.172 -0.1665 17.565
NMC-G1 GDSC1; GDSC2; CTRP2 3.2741 7.384 2.1995 15.8702
SF126 GDSC1; GDSC2; CTRP2 3.338 9.2187 1.4075 18.8109
CAS-1 GDSC1; GDSC2 3.5096 6.3258 1.9734 6.4939
SW1783 GDSC1; GDSC2; CTRP2 3.5394 8.6061 1.8938 16.422
D-263MG GDSC1; GDSC2 3.6375 5.064 2.6978 2.5332
PFSK-1 GDSC1; GDSC2 3.7022 13.2498 -1.3288 23.9369
LN-229 GDSC1; GDSC2; CTRP2; CTRP1 3.7623 4.3921 3.7561 8.6504
D-423MG GDSC1; GDSC2 3.7738 9.308 -1.1331 7.0942
SK-MG-1 GDSC1; GDSC2 3.836 7.1841 1.8007 6.6773
U-251MG GDSC1; GDSC2; CTRP2 3.8684 5.7474 3.5185 9.1187
U-118MG GDSC1; GDSC2; CTRP2 3.9016 10.0886 1.5164 17.0578
D-245MG GDSC2 3.9058 7.2334 -0.157 2.0785
KS-1 [Human Krukenberg tumour] GDSC1; GDSC2 4.1722 11.2663 0.0342 14.5358
Hs 683 GDSC1; GDSC2; CTRP2 4.3735 11.3265 1.3281 16.7404
D-542MG GDSC1; GDSC2 4.4538 14.2583 -3.0188 14.8212
LNZTA3WT4 GDSC1; GDSC2 4.5066 7.0301 2.3375 2.8498
KALS-1 GDSC1; GDSC2; CTRP2 5.1525 7.8566 3.7273 5.3309
GaMG GDSC1; GDSC2; CTRP2; CTRP1 5.3366 8.7652 3.4318 6.3149
LN-18 GDSC1; GDSC2; CTRP2 5.8757 12.7894 1.1217 9.904
M059K CTRP2 6.0742 14.7799 1.006 14.6319
SNU-738 CTRP2 6.1653 9.1692 3.8247 3.3241
U-87MG ATCC GDSC1; GDSC2; CTRP2 6.2012 8.6727 4.0797 2.2909
GMS-10 CTRP2 6.5281 7.6774 4.6667 0.1985
SF295 GDSC1; GDSC2; CTRP2; CTRP1 6.6161 8.6404 4.339 1.0382
DK-MG GDSC1; GDSC2; CTRP2 6.7673 11.1565 3.2772 4.6835
SW1088 GDSC1; GDSC2; CTRP2 6.7941 10.4736 3.6123 3.362
TM-31 CTRP2 7.0149 8.3349 4.6168 0.1479
SNU-1105 CTRP2 7.022 18.8082 -0.267 17.3123
A-172 GDSC1; GDSC2; CTRP2 7.0321 8.6249 4.519 0.3016
SNU-489 CTRP2 7.0499 8.1108 4.7059 0.0501
YKG-1 GDSC1; GDSC2; CTRP2 7.1285 8.3269 4.6604 0.0787
CCF-STTG1 CTRP2 7.1509 8.4148 4.6384 0.0972
SNU-201 CTRP2 7.1597 15.498 1.4583 11.1719
8-MG-BA GDSC1; GDSC2; CTRP2 7.3011 8.542 4.6478 0.0686
YH-13 GDSC1; GDSC2; CTRP2 7.4302 9.1328 4.4896 0.2323
GOS-3 CTRP2 7.6956 9.3087 4.5257 0.1304
KNS-42 GDSC1; GDSC2; CTRP2 7.721 14.6096 2.2661 7.3355
Becker GDSC1; GDSC2; CTRP2 8.9359 16.3272 2.2214 6.047
T98G GDSC1; GDSC2; CTRP2 9.1412 17.6835 1.7249 7.5572
42-MG-BA GDSC1; GDSC2; CTRP2 9.3439 17.8161 1.7863 7.1141
SNB-75 GDSC1; GDSC2; CTRP2 10.2151 21.4276 0.6561 9.8839
ONS-76 GDSC1; GDSC2; CTRP2 12.8486 25.3971 0.4004 7.9479
⏷ Show the Full List of 68 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1; GDSC2 -1.9383 0.1599 -1.946 42.8378
TGBC1TKB GDSC1; GDSC2 0.6141 3.6268 0.2782 23.4785
ETK-1 GDSC1; GDSC2 3.2794 5.5731 2.1607 6.0637
Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-265 CTRP2; CTRP1 -1.4726 2.3247 -1.5498 43.6474
HEC-108 CTRP2; CTRP1 -0.5255 3.0013 -0.6215 37.4624
MFE-280 GDSC1; GDSC2 0.5521 2.7342 0.437 23.0242
HEC-1-A CTRP2 1.564 2.3463 1.5639 23.1872
JHUEM-1 CTRP2 1.5766 5.0841 1.249 24.2426
MFE-296 GDSC1; GDSC2; CTRP2 2.1468 3.6814 2.125 19.3774
JHUEM-3 CTRP2 2.1979 5.2266 1.8863 20.0588
KLE GDSC1; GDSC2; CTRP2; CTRP1 2.2886 6.4986 1.549 21.1143
MFE-319 GDSC1; GDSC2; CTRP2; CTRP1 3.1652 9.953 0.8976 21.2136
JHUEM-2 CTRP2; CTRP1 3.8787 7.0273 2.9758 11.3245
HEC-6 CTRP2; CTRP1 3.9439 12.7583 0.2446 21.6545
HEC-59 CTRP2; CTRP1 4.2584 4.9418 4.2142 5.4799
HEC-251 CTRP2; CTRP1 5.4881 15.4346 0.2242 18.5138
JHUEM-7 CTRP2 5.9233 11.2756 2.6275 8.5601
ESS-1 GDSC1; GDSC2; CTRP2 6.0421 12.4594 2.132 10.3654
HEC-151 CTRP2; CTRP1 6.3152 8.1335 4.3992 1.0913
RL95-2 GDSC1; GDSC2; CTRP2 6.837 14.8691 1.5341 11.3898
AN3-CA GDSC1; GDSC2; CTRP2 7.0771 16.0918 1.1095 12.5794
EN GDSC1; GDSC2; CTRP2 7.4992 13.2105 2.7808 5.668
HEC-50B CTRP2 7.5732 9.3538 4.465 0.2332
EFE-184 CTRP2 7.6271 13.1312 2.897 5.0756
HEC-1-B CTRP2 10.1241 23.9899 -0.603 13.8304
Ishikawa (Heraklio) 02 ER- CTRP2; CTRP1 6.5036 7.5023 4.7345 0.1234
⏷ Show the Full List of 23 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TUHR14TKB CTRP2 -8.804 -1.1395 -8.9333 80.1356
TUHR10TKB CTRP2 -3.7082 -1.0473 -3.7099 58.2709
KTCTL-1M GDSC1; GDSC2 -1.6507 1.4748 -2.0351 28.5759
TUHR4TKB CTRP2 -0.7061 2.32 -0.7478 38.4394
A-704 GDSC1; GDSC2 -0.6043 3.246 -0.9424 33.2764
Caki-2 CTRP2 -0.3815 2.0283 -0.397 36.1989
HA7-RCC GDSC1; GDSC2 0.2848 2.7232 -0.5118 11.8739
LB996-RCC GDSC1; GDSC2 0.5868 2.9625 0.427 22.9334
KTCTL-195 GDSC1; GDSC2 0.6377 3.93 0.2066 23.7061
NCC021 GDSC1; GDSC2 0.9165 4.0532 -0.5967 10.3407
BB65-RCC GDSC1; GDSC2 0.9548 3.1616 -0.1187 7.2154
NCC010 GDSC1; GDSC2 1.1001 4.2626 -0.5487 9.505
KTCTL-13 GDSC1; GDSC2 1.1465 4.5808 -0.6698 10.13
UO-31 GDSC1; GDSC2; CTRP2 1.3089 2.8046 1.3033 24.9052
LB2241-RCC GDSC1; GDSC2 1.4698 3.6773 0.0298 4.904
769-P GDSC1; GDSC2; CTRP2 1.4882 4.5829 1.279 24.4116
A-498 GDSC1; GDSC2 1.7549 9.0179 -0.9182 24.7428
RCC10RGB GDSC1; GDSC2; CTRP2; CTRP1 1.9729 5.0906 1.6823 21.5538
LB1047-RCC GDSC1; GDSC2 2.1752 6.308 -0.7499 8.043
KTCTL-21 GDSC1; GDSC2 2.2493 6.9634 -1.0156 9.4396
786-O GDSC1; GDSC2; CTRP2 2.3334 6.3992 1.6304 20.6076
VMRC-RCW GDSC1; GDSC2; CTRP2; CTRP1 2.3643 6.4531 1.6473 20.5325
Caki-1 GDSC1; GDSC2; CTRP2 2.4763 3.7102 2.4648 17.1477
KTCTL-140 GDSC1; GDSC2 2.5741 7.666 -1.1299 9.3784
SW13 GDSC1; GDSC2 2.6694 4.0075 2.3517 6.7704
RXF 393L GDSC1; GDSC2 2.7991 7.1983 -0.7588 6.8065
BFTC-909 GDSC1; GDSC2; CTRP2 2.8269 5.8327 2.3711 16.4166
VMRC-RCZ GDSC1; GDSC2; CTRP2 3.1316 5.2382 2.9009 13.5582
KTCTL-26A GDSC1; GDSC2 3.9348 11.8811 -2.2321 12.3283
SW156 GDSC1; GDSC2 4.1159 6.1761 0.3333 0.3331
KMRC-2 CTRP2 4.2128 6.725 3.4397 8.5426
TK-10 GDSC1; GDSC2 4.7823 8.2561 1.9398 4.2999
KMRC-3 CTRP2 5.004 11.5785 1.7436 13.8191
SN12C GDSC1; GDSC2 5.5265 9.1991 1.9536 3.2216
SNU-1272 CTRP2 5.8417 15.4621 0.4841 16.9056
CAL-54 GDSC1; GDSC2; CTRP2 5.9364 10.857 2.8439 7.6517
KMRC-1 GDSC1; GDSC2; CTRP2 6.0706 9.9976 3.3622 5.3173
ACHN GDSC1; GDSC2; CTRP2 7.8004 13.324 2.9135 4.8135
KMRC-20 GDSC1; GDSC2; CTRP2 8.3461 15.6377 2.1812 6.8674
OS-RC-2 GDSC1; GDSC2; CTRP2 8.7351 17.8751 1.3822 9.2497
⏷ Show the Full List of 40 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 63 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1417 GDSC1; GDSC2; CTRP2 -1.3397 0.6013 -1.341 42.5356
SNU-175 GDSC2; CTRP2; CTRP1 -0.7063 2.8786 -0.7989 38.6465
SK-CO-1 GDSC1; GDSC2; CTRP2; CTRP1 -0.6284 3.3551 -0.7793 38.296
SW480 CTRP1 0.062 1.9213 0.0574 70.3343
SW626 GDSC1; GDSC2 0.2086 1.7151 0.1942 25.3974
DiFi GDSC1; GDSC2 0.3163 4.1353 -0.2115 26.7045
SW48 GDSC1; GDSC2; CTRP2; CTRP1 0.3607 4.0535 0.167 31.9092
RCM-1 [Human ESC] GDSC1; GDSC2; CTRP2; CTRP1 0.5456 2.3817 0.5381 30.064
SW620 GDSC1; GDSC2; CTRP2; CTRP1 0.6557 2.6174 0.643 29.3487
COLO205 GDSC1; GDSC2; CTRP2; CTRP1 0.791 3.3365 0.7342 28.5968
SW1116 GDSC1; GDSC2 0.8936 2.8683 0.7805 20.2383
LS123 GDSC1; GDSC2; CTRP2; CTRP1 0.9677 4.1188 0.8111 27.7605
SNU-283 GDSC2 1.188 3.3651 -0.0298 5.9935
SW948 GDSC1; GDSC2; CTRP2; CTRP1 1.3304 4.0795 1.2093 25.2275
SNU-81 GDSC1; GDSC2; CTRP2; CTRP1 1.4673 6.7191 0.5873 26.9688
HCC2998 GDSC1; GDSC2 1.5001 6.0644 0.2424 20.5991
GP5d GDSC1; GDSC2 1.5043 3.7738 1.1988 16.1273
SNU-C4 CTRP2; CTRP1 1.57 6.16 0.9025 25.5636
NCI-H508 GDSC1; GDSC2; CTRP1 1.5902 5.8684 1.025 26.8337
DLD-1 CTRP2; CTRP1 1.6245 3.7277 1.573 23.0318
SW1463 GDSC1; GDSC2; CTRP2 1.6349 5.4752 1.1975 24.2471
MDST8 GDSC1; GDSC2; CTRP2; CTRP1 1.7776 5.1872 1.4421 23.0105
SNU-503 CTRP2 1.7865 10.8719 -0.8884 30.4704
COLO 678 GDSC1; GDSC2; CTRP2; CTRP1 2.0026 4.6033 1.836 20.9154
NCI-H747 GDSC1; GDSC2; CTRP2 2.0748 3.5666 2.0579 19.8403
LS513 GDSC1; GDSC2; CTRP2; CTRP1 2.2081 5.3097 1.8758 20.1433
COLO 320 CTRP2; CTRP1 2.2256 5.4262 1.856 20.0859
CaR-1 GDSC1; GDSC2 2.2773 4.249 1.842 10.4863
SNU-1040 GDSC2; CTRP1 2.3023 5.7349 1.8421 25.5479
SW837 GDSC1; GDSC2 2.3242 6.0797 1.0434 14.2679
C2BBe1 GDSC1; GDSC2; CTRP2; CTRP1 2.411 5.2155 2.125 18.6281
LS180 GDSC1; GDSC2; CTRP2; CTRP1 2.5763 4.4129 2.4947 16.8017
CL-40 CTRP1 2.6742 10.5775 0.1263 42.8529
LS1034 GDSC1; GDSC2; CTRP2 2.6927 5.4978 2.3412 16.9179
GP2d CTRP1 2.8344 7.0877 1.8841 37.1367
CL-11 GDSC1; GDSC2; CTRP2 3.0064 8.083 1.6128 18.8532
CW-2 GDSC1; GDSC2; CTRP2; CTRP1 3.0165 6.7146 2.2314 16.5031
SNU-C5 GDSC1; GDSC2; CTRP2; CTRP1 3.0312 5.5008 2.7113 14.6356
HT-55 GDSC1; GDSC2; CTRP2; CTRP1 3.063 5.3778 2.786 14.2663
CL-34 CTRP1 3.1151 6.2272 2.5342 31.7784
LS411N GDSC1; GDSC2; CTRP2; CTRP1 3.288 7.7238 2.066 16.4405
T84 GDSC1; GDSC2; CTRP2 3.3563 7.1893 2.3702 14.9837
CCK-81 GDSC1; GDSC2; CTRP2 3.5102 8.2043 2.0559 15.8487
COLO 320HSR GDSC1; GDSC2 3.576 5.2271 2.5719 3.2922
SNU-C1 GDSC1; GDSC2; CTRP2 3.7399 11.7051 0.573 20.9296
HT115 GDSC1; GDSC2; CTRP2; CTRP1 4.1266 7.185 3.1454 10.0336
SNU-C2A CTRP2; CTRP1 4.5662 14.349 -0.0029 21.1134
SW403 CTRP1 4.8125 8.5486 3.1047 18.206
HCT 116 GDSC1; GDSC2; CTRP2; CTRP1 4.8268 6.9827 3.8973 5.3445
SNU-C2B GDSC1; GDSC2 5.3136 10.9116 1.031 7.7372
KM12 GDSC1; GDSC2; CTRP2; CTRP1 5.4465 9.9759 2.9154 8.2731
HCT 8 CTRP2; CTRP1 5.6207 10.2567 2.9121 7.9795
HT-29 GDSC1; GDSC2; CTRP2; CTRP1 6.1987 7.5723 4.577 0.6228
HCC-56 CTRP2 6.5981 7.5708 4.731 0.0869
COLO201 CTRP2 6.7772 8.1154 4.6048 0.2293
OUMS-23 CTRP2 6.7804 7.8641 4.6953 0.0959
SNU-1033 CTRP2 6.786 15.2394 1.3155 12.2884
NCI-H716 GDSC1; GDSC2; CTRP2 7.1128 16.5532 0.9095 13.2394
SNU-407 GDSC1; GDSC2; CTRP2 7.4203 12.519 3.0527 4.7358
RKO GDSC1; GDSC2; CTRP2; CTRP1 7.4908 8.9069 4.6048 0.0975
LoVo GDSC1; GDSC2; CTRP2; CTRP1 7.8196 14.801 2.2516 7.3289
SNU-61 GDSC1; GDSC2; CTRP2; CTRP1 7.8445 16.4314 1.4932 10.106
HCT 15 GDSC1; GDSC2; CTRP2 8.2222 14.4297 2.6611 5.2625
⏷ Show the Full List of 63 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1; GDSC2 -0.4356 3.4925 -0.8266 32.1369
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-886 CTRP2 -12.0502 -2.2369 -12.2405 86.1567
Li-7 CTRP2 -2.5318 4.078 -2.9813 50.4016
SNU-878 CTRP2 -2.0464 2.1047 -2.133 47.3428
JHH-5 CTRP2 -0.5527 2.7344 -0.622 37.5037
Huh-7 GDSC1; GDSC2 0.9668 4.064 0.5166 21.1352
JHH-7 GDSC1; GDSC2 1.2275 5.5969 0.175 21.7931
HLE GDSC1; GDSC2 1.6182 4.0809 1.2115 15.6697
SNU-761 CTRP2 1.9264 3.5312 -0.5319 0.5063
JHH-2 GDSC1; GDSC2 2.1485 4.2814 1.6941 11.6137
SNU-398 GDSC1; GDSC2; CTRP2; CTRP1 2.3589 5.9843 1.8164 19.9172
SNU-387 GDSC1; GDSC2; CTRP2 2.4258 5.2892 2.1163 18.5369
SNU-182 CTRP2 2.604 10.3483 0.1596 25.1309
SNU-423 GDSC1; GDSC2; CTRP2 2.6694 7.0193 1.7357 19.2738
Hep-G2/C3A GDSC1; GDSC2 3.433 4.735 2.7056 2.9124
JHH-6 GDSC1; GDSC2; CTRP2; CTRP1 3.6763 9.4964 1.6039 17.3126
SNU-449 GDSC1; GDSC2; CTRP2; CTRP1 3.8468 6.231 3.3004 10.1121
PLC/PRF/5 CTRP2 4.2652 7.5204 3.1093 9.7738
SK-HEP-1 GDSC1; GDSC2; CTRP2 5.1955 10.8955 2.2438 11.4335
Hep-G2 CTRP2; CTRP1 6.2373 7.5523 4.6037 0.5204
HLF CTRP2 6.5986 12.2881 2.6218 7.5171
HuH-6 CTRP2 6.6095 8.9159 4.2048 1.42
HuH-1 GDSC1; GDSC2; CTRP2 7.0331 8.576 4.5373 0.2677
Hep 3B2.1-7 GDSC1; GDSC2; CTRP2 7.1206 8.9227 4.4439 0.4182
SNU-475 CTRP2 7.2148 8.8129 4.5221 0.2391
JHH-1 GDSC1; GDSC2; CTRP2 7.2458 15.6656 1.4378 11.1171
JHH-4 GDSC1; GDSC2; CTRP2 8.4235 14.4859 2.7537 4.712
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 227 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1385 CTRP2 -5.8491 -3.2017 -5.8494 72.316
NCI-H1105 GDSC1; GDSC2; CTRP2; CTRP1 -4.5102 -2.291 -4.5103 63.6593
NCI-H187 GDSC1 -4.4853 -2.6098 -4.488 68.0367
NCI-H146 GDSC1; GDSC2 -4.4677 -2.4829 -4.4719 54.8277
NCI-H1963 GDSC2; CTRP1 -4.3052 -2.517 -4.3053 66.7537
NCI-H847 GDSC1; GDSC2 -4.174 -2.287 -4.1743 60.9818
COR-L303 GDSC2 -3.9432 -2.5894 -3.9436 49.6054
HCC4006 CTRP2; CTRP1 -3.5382 0.5499 -3.5745 56.9558
DMS 454 CTRP2 -3.4539 0.7514 -3.4985 56.3486
COR-L32 GDSC2 -3.4165 -1.6919 -3.4221 44.3415
DMS 53 GDSC1; GDSC2; CTRP2 -3.3353 -1.2753 -3.3355 55.8221
NCI-H720 GDSC1; GDSC2 -3.2858 -1.0055 -3.2894 53.7577
Lu-135 GDSC1; GDSC2 -3.1917 -0.7452 -3.198 52.9876
NCI-H250 GDSC2 -3.0483 -0.6333 -3.1022 40.8481
NCI-H1930 CTRP1 -2.9285 0.6554 -2.9527 90.0216
COR-L311 GDSC2 -2.8319 -0.9212 -2.8334 50.0844
NCI-H2171 GDSC2 -2.6076 -0.5496 -2.6466 36.3894
NCI-H889 CTRP2 -2.6019 -0.8098 -2.602 50.9402
NCI-H1836 GDSC1; GDSC2; CTRP1 -2.5185 0.3716 -2.5267 53.9916
Lu-134-A GDSC1; GDSC2 -2.5026 0.0621 -2.6134 35.6721
NCI-H748 GDSC2 -2.4988 -0.6171 -2.5271 35.2494
NCI-H1341 GDSC1; GDSC2; CTRP2 -2.4166 -0.1475 -2.4181 49.7068
COR-L95 GDSC1; GDSC2; CTRP2 -2.3452 -0.4847 -2.3454 49.2305
NCI-H2106 CTRP2 -2.1682 0.8105 -2.1814 48.0669
NCI-H510A GDSC1; GDSC2; CTRP2 -2.1639 2.3068 -2.2784 48.1194
DMS 79 GDSC1; GDSC2 -2.1513 -0.1321 -2.209 31.912
NCI-H209 GDSC1; GDSC2; CTRP2 -2.0274 0.3247 -2.0418 40.3075
HCC15 GDSC1; GDSC2; CTRP2; CTRP1 -1.9525 0.1401 -1.9537 46.6685
COR-L279 GDSC1; GDSC2; CTRP1 -1.8922 0.0851 -1.893 49.5664
IST-SL2 GDSC1; GDSC2 -1.8192 0.6333 -1.9849 29.135
NCI-H211 GDSC1; GDSC2; CTRP2 -1.7928 0.203 -1.7938 45.553
NCI-H69 GDSC1; GDSC2; CTRP2 -1.6545 2.5115 -1.8297 41.329
NCI-H345 GDSC1; GDSC2 -1.6293 0.5863 -1.768 27.0981
NCI-H524 GDSC1; GDSC2 -1.6019 1.9802 -1.7537 40.5614
T3M-10 CTRP2; CTRP1 -1.5631 1.7297 -1.5988 44.157
NCI-H835 GDSC1; GDSC2 -1.4533 1.1248 -1.4927 39.0104
NCI-H1770 GDSC1; GDSC2 -1.3338 3.1947 -2.3591 28.6936
NCI-H1048 GDSC1; GDSC2; CTRP1 -1.2955 2.8408 -1.42 45.536
COR-L88 GDSC1; GDSC2; CTRP1 -1.2738 0.6615 -1.2751 45.1598
IST-SL1 GDSC1; GDSC2 -1.2641 0.7959 -1.4183 23.5233
Lu-139 GDSC1; GDSC2 -1.1745 1.3532 -1.2197 36.7701
NCI-H526 GDSC1; GDSC2; CTRP2 -1.1568 2.8712 -1.2772 41.6212
NCI-H1304 GDSC1 -1.027 4.6562 -2.7054 34.4383
Ms-1 GDSC1; GDSC2 -1.0174 2.7923 -1.2803 36.2833
NCI-H1876 GDSC1; GDSC2; CTRP1 -1.0138 3.1135 -1.1565 43.6277
NCI-H1155 GDSC1; GDSC2; CTRP2 -1.0024 2.1363 -1.0433 40.4041
SCLC-21H CTRP1 -0.9447 4.0333 -1.2442 71.8822
HOP-92 GDSC1; GDSC2; CTRP2 -0.8658 2.9985 -0.9839 39.7084
CPC-N GDSC1; GDSC2 -0.8322 1.1926 -0.8523 33.8902
NCI-H64 GDSC1; GDSC2 -0.7018 1.2927 -0.7231 32.8342
NCI-H2196 GDSC2; CTRP2 -0.6517 5.048 -1.1729 39.3009
NCI-H1435 GDSC1; GDSC2; CTRP2; CTRP1 -0.5693 2.4316 -0.6129 37.5967
EBC-1 GDSC1; GDSC2; CTRP2; CTRP1 -0.2418 1.9651 -0.252 35.3133
NCI-H2141 GDSC1; GDSC2; CTRP1 -0.0468 3.9554 -0.2552 37.0744
HCC1833 CTRP2; CTRP1 0.0334 6.565 -0.8999 36.1239
NCI-H2227 GDSC1; GDSC2 0.1763 4.4743 -1.4637 17.9887
COR-L321 GDSC1; GDSC2 0.1946 2.5515 -0.5185 12.2422
COR-L51 CTRP2; CTRP1 0.1949 1.8833 0.1921 32.3827
NCI-H1092 GDSC1; GDSC2; CTRP2 0.3359 5.1437 -0.1216 32.8414
COLO 668 GDSC1; GDSC2; CTRP1 0.4811 2.8965 0.4474 32.7624
NCI-H1694 GDSC1; GDSC2; CTRP2; CTRP1 0.4965 4.5524 0.2084 31.3197
NCI-H2066 GDSC1; GDSC2 0.532 3.0624 0.344 23.5003
Calu-3 GDSC1; GDSC2; CTRP2; CTRP1 0.5712 3.8473 0.4309 30.3381
NCI-H1436 GDSC1; GDSC2 0.6442 4.1373 -0.8742 12.9051
LOU-NH91 GDSC1; GDSC2; CTRP2 0.6735 4.7072 0.362 30.1637
NCI-H3255 GDSC1; GDSC2; CTRP1 0.6846 2.8741 0.6602 31.2785
A-427 GDSC1; GDSC2 0.6945 4.1431 -0.8329 12.4911
NCI-H2170 GDSC1; GDSC2; CTRP2 0.8051 4.4894 0.5568 29.0823
SHP-77 GDSC1; GDSC2; CTRP2; CTRP1 0.8699 3.2148 0.8285 28.0195
COR-L105 GDSC1; GDSC2; CTRP2 1.0231 3.5079 0.9603 27.0019
SBC-1 GDSC1; GDSC2 1.0465 4.1961 -0.5595 9.726
NCI-H2135 GDSC1; GDSC2 1.0975 4.2134 -0.5262 9.3714
Sq-1 CTRP2; CTRP1 1.098 4.0748 0.9597 26.8318
NCI-H1650 GDSC1; GDSC2; CTRP2 1.1403 5.0305 0.7876 27.2208
LC-2/ad GDSC1; GDSC2 1.2737 3.7625 -0.1603 6.5869
Calu-6 GDSC1; GDSC2; CTRP2; CTRP1 1.2894 4.5639 1.0689 25.8443
NCI-H2810 GDSC1; GDSC2 1.3258 2.9006 0.3056 3.5352
NCI-H290 GDSC1; GDSC2 1.3827 3.1986 0.201 4.0488
HCC2935 CTRP2; CTRP1 1.3965 5.1599 1.0339 25.6312
NCI-H1648 GDSC1; GDSC2 1.4024 4.5325 0.8062 18.2927
NCI-H1944 GDSC1; GDSC2; CTRP2; CTRP1 1.4091 5.18 1.042 25.5635
NCI-H2444 GDSC1; GDSC2; CTRP2 1.4432 3.7838 -0.0421 4.9214
LK-2 GDSC1; GDSC2 1.4792 4.3137 0.9739 17.2505
NCI-H1563 GDSC1; GDSC2; CTRP2 1.5324 3.894 1.4535 23.665
NCI-H2085 GDSC1; GDSC2; CTRP2 1.5474 6.1495 0.8779 25.6481
NCI-H2029 GDSC1; GDSC2; CTRP2; CTRP1 1.6841 4.4212 1.5283 22.9954
UMC-11 GDSC1; GDSC2 1.726 4.9935 0.9511 16.5394
LB647-SCLC GDSC1; GDSC2 1.7928 5.1396 -0.452 7.1159
NCI-H1581 GDSC1; GDSC2; CTRP2 1.9215 3.6745 1.8903 20.9103
NCI-H596 GDSC1; GDSC2; CTRP1 1.9407 6.7122 1.0955 25.438
NCI-H1993 GDSC1; GDSC2 1.9545 4.3523 1.4613 13.3606
NCI-H810 GDSC1; GDSC2; CTRP2; CTRP1 2.067 3.9564 2.0156 20.0868
NCI-H446 GDSC1; GDSC2; CTRP2 2.0824 7.8739 0.7622 24.495
ABC-1 GDSC1; GDSC2 2.1176 7.8137 -1.5263 12.6651
NCI-H2081 GDSC1; GDSC2; CTRP2; CTRP1 2.1365 4.8819 1.9161 20.2158
EMC-BAC-1 GDSC1; GDSC2 2.1778 9.9042 -2.5126 17.5886
BEN GDSC1; GDSC2; CTRP2; CTRP1 2.2012 5.8898 1.6794 20.8826
Lu-165 GDSC1; GDSC2 2.2329 4.5811 1.6521 11.5439
NCI-H1573 GDSC1; GDSC2; CTRP1 2.2352 3.6628 2.2186 20.1944
NCI-H2342 GDSC1; GDSC2; CTRP2; CTRP1 2.2356 5.5742 1.8231 20.2533
NCI-H1693 GDSC1; GDSC2; CTRP2 2.3144 8.7104 0.6311 24.311
NCI-H1688 GDSC1; GDSC2 2.4413 7.6887 0.3673 17.2216
NCI-H82 GDSC1; GDSC2; CTRP1 2.4777 4.9562 2.2693 19.1826
NCI-H2804 GDSC1; GDSC2 2.5107 16.7712 -5.6647 27.743
NCI-H2347 GDSC1; GDSC2 2.518 7.04 0.7568 15.1357
NCI-H2087 GDSC1; GDSC2; CTRP2 2.5332 5.7774 2.0737 18.3772
NCI-H740 GDSC2 2.6355 8.3662 -1.4253 10.8973
HOP-62 GDSC1; GDSC2; CTRP2 2.6362 3.8036 2.6249 16.0815
HCC2279 CTRP2 2.6423 8.7773 0.9306 22.363
VMRC-LCD GDSC1; GDSC2; CTRP2; CTRP1 2.6559 5.2867 2.3709 16.9982
SBC-3 GDSC1; GDSC2 2.6737 4.1955 2.2726 7.1411
SW1573 GDSC1; GDSC2 2.7009 5.7296 1.5681 10.5835
Lu-99 CTRP2; CTRP1 2.7207 5.0417 2.5119 16.2914
NCI-H1915 GDSC1; GDSC2; CTRP2; CTRP1 2.7226 6.8794 1.8551 18.7491
NCI-H2803 GDSC2 2.7284 4.6977 0.3159 1.2207
NCI-H2731 GDSC1; GDSC2 2.7326 4.7881 2.0541 8.0472
NCI-H1734 GDSC2; CTRP2 2.7676 7.2198 1.3203 15.4149
NCI-H2122 GDSC1; GDSC2; CTRP2; CTRP1 2.8048 7.4919 1.6789 19.2025
NCI-H2869 GDSC1; GDSC2 2.8404 5.9246 -0.1504 3.3582
Lu-99A GDSC1; GDSC2 2.8451 6.374 1.3823 11.136
HCC1195 CTRP2; CTRP1 2.8889 7.0318 1.9645 17.8785
NCI-H2369 GDSC1; GDSC2 2.91 3.8403 2.6716 4.4572
RERF-LC-A1 CTRP2 2.962 4.1366 2.9407 13.9449
NCI-H1793 GDSC1; GDSC2; CTRP2; CTRP1 2.9708 5.6531 2.5941 15.2475
COLO 699 CTRP2; CTRP1 3.0405 7.1037 2.0906 16.9858
NCI-H2073 CTRP1 3.0895 11.6985 -0.0174 40.9305
NCI-H1755 GDSC1; GDSC2; CTRP2; CTRP1 3.1215 4.8104 3.0068 13.2907
EMC-BAC-2 GDSC1; GDSC2 3.1444 6.4311 1.617 9.1786
RERF-LC-Sq1 GDSC1; GDSC2 3.1951 9.725 0.0141 16.8863
HCC78 GDSC1; GDSC2; CTRP2; CTRP1 3.1985 10.2301 0.7964 21.4969
SBC-5 GDSC1; GDSC2; CTRP2 3.1996 4.267 3.1783 12.3621
IA-LM GDSC1; GDSC2; CTRP2 3.2216 8.5625 1.6047 18.3382
NCI-H1651 GDSC1; GDSC2 3.2444 5.1539 2.3406 5.2251
NCI-H358 GDSC1; GDSC2; CTRP2; CTRP1 3.2842 5.5567 2.9665 12.9497
NCI-H441 GDSC1; GDSC2; CTRP2; CTRP1 3.2846 7.2596 2.2721 15.636
NCI-H322M GDSC1; GDSC2 3.2939 5.4612 2.2289 5.6791
NCI-H1666 GDSC1; GDSC2; CTRP2; CTRP1 3.3193 4.8898 3.2037 11.9783
HCC44 GDSC1; GDSC2; CTRP2; CTRP1 3.3622 4.9524 3.2352 11.7338
NCI-H727 GDSC1; GDSC2; CTRP2; CTRP1 3.3778 6.8938 2.5291 14.3809
HARA [Human squamous cell lung carcinoma] GDSC1; GDSC2; CTRP2; CTRP1 3.3791 6.6834 2.6219 14.0123
DV-90 CTRP2; CTRP1 3.3799 4.8754 3.2732 11.544
NCI-H841 GDSC1; GDSC2; CTRP2; CTRP1 3.3954 6.067 2.8949 12.9072
NCI-H1781 GDSC1; GDSC2; CTRP1 3.3957 5.7057 3.0337 13.2608
NCI-H2722 GDSC1; GDSC2 3.3981 8.1586 0.9668 11.8563
NCI-H1975 GDSC1; GDSC2; CTRP2; CTRP1 3.4388 7.9776 2.099 15.9313
Lu-65 GDSC1; GDSC2; CTRP2; CTRP1 3.5201 5.3392 3.2954 11.0399
LC-1/sq GDSC1; GDSC2 3.6322 11.6555 -0.5891 18.4346
NCI-H1373 CTRP2; CTRP1 3.6428 9.8413 1.4048 18.1623
ChaGo-K-1 GDSC1; GDSC2; CTRP2; CTRP1 3.6509 5.0306 3.5299 9.7931
NCI-H1355 GDSC1; GDSC2; CTRP2; CTRP1 3.6966 5.9517 3.2599 10.6738
SK-MES-1 GDSC1; GDSC2; CTRP2 3.7454 5.699 3.4065 9.8899
NCI-H2405 GDSC1; GDSC2; CTRP2; CTRP1 3.7558 8.1176 2.3431 14.1805
NCI-H522 GDSC1; GDSC2; CTRP2; CTRP1 3.7615 5.1801 3.6081 9.1757
NCI-H2373 GDSC1; GDSC2 3.811 5.6513 2.5353 3.0214
NCI-H650 GDSC1; GDSC2; CTRP2; CTRP1 3.8122 4.6835 3.7794 8.4092
NCI-H1299 GDSC1; GDSC2; CTRP2; CTRP1 3.82 6.6395 3.0934 11.0015
HCC33 GDSC2; CTRP1 3.8538 6.8608 3.0274 11.9769
NCI-H2818 GDSC1; GDSC2 3.8567 5.937 2.4289 3.468
SK-LU-1 GDSC1; GDSC2; CTRP2; CTRP1 3.8781 11.2076 0.9524 19.3177
NCI-H2461 GDSC1; GDSC2 3.917 6.2625 2.3132 3.9338
LCLC-103H GDSC1; GDSC2; CTRP2; CTRP1 3.9171 5.1468 3.7877 8.0549
NCI-H2023 GDSC1; GDSC2; CTRP2; CTRP1 3.9336 10.3687 1.4163 17.4453
HCC1438 CTRP2 3.9945 15.8922 -1.2775 26.032
LC-1/sq-SF CTRP2; CTRP1 4.0122 5.0847 3.9095 7.3263
PaCa-3 GDSC1; GDSC2 4.0181 9.2425 0.9199 10.705
RERF-LC-KJ GDSC1; GDSC2; CTRP1 4.048 5.5816 3.7791 8.2586
NCI-H2286 CTRP2; CTRP1 4.0843 11.22 1.1327 18.1843
NCI-H1838 GDSC1; GDSC2; CTRP2 4.095 9.3747 2.0447 14.5233
NCI-H1437 GDSC1; GDSC2; CTRP1 4.1214 5.8868 3.7324 8.2381
HCC2108 CTRP2; CTRP1 4.1541 5.5935 3.8874 6.9994
NCI-H1184 CTRP2 4.1822 12.036 0.8064 19.1004
NCI-H3122 GDSC1; GDSC2 4.2886 6.4343 2.4786 2.5114
EPLC-272H GDSC1; GDSC2; CTRP2; CTRP1 4.3155 8.9764 2.4507 12.4589
NCI-H2795 GDSC1; GDSC2 4.3422 7.4942 2.0126 4.6632
NCI-H2291 GDSC1; GDSC2; CTRP2 4.366 10.3534 1.1835 12.3742
NCI-H1792 GDSC1; GDSC2; CTRP2; CTRP1 4.3888 9.0746 2.4685 12.2261
HCC95 CTRP2 4.4951 11.1153 1.5398 15.6621
HCC366 GDSC1; GDSC2; CTRP2 4.5105 14.953 -0.3616 22.3042
NCI-H2030 GDSC1; GDSC2; CTRP2; CTRP1 4.6402 9.245 2.6075 11.1179
HCC1359 CTRP1 4.6731 5.1198 4.6198 5.9167
LUDLU-1 CTRP2 4.7163 6.8616 3.8497 5.693
PC-14 GDSC1; GDSC2; CTRP2 4.8285 7.1113 2.4866 1.6474
HCC1588 CTRP2 4.8419 14.559 0.1173 20.0866
COR-L23 GDSC1; GDSC2; CTRP1 4.8612 7.9682 3.4364 7.718
LCLC-97TM1 GDSC1; GDSC2; CTRP2; CTRP1 4.9066 12.8188 1.0513 16.7426
NCI-H226 GDSC1; GDSC2; CTRP2 4.9425 7.6971 2.2917 2.2888
NCI-H2591 GDSC1; GDSC2 4.95 7.9029 2.2038 2.8506
NCI-H2595 GDSC1; GDSC2 5.0122 11.4298 0.5757 10.3826
NCI-H520 GDSC1; GDSC2; CTRP2 5.023 8.6407 3.2284 7.6732
NCI-H513 GDSC1; GDSC2 5.0644 8.3296 2.078 3.261
NCI-H23 GDSC1; GDSC2; CTRP2; CTRP1 5.1729 11.7116 1.827 13.2313
NCI-H2228 GDSC1; GDSC2; CTRP2 5.1775 12.1278 0.3532 10.3304
SW1271 GDSC1; GDSC2; CTRP2 5.4962 8.4019 2.2833 1.7577
EKVX GDSC1; GDSC2; CTRP2 5.5589 13.7288 1.1232 15.138
NCI-H2009 GDSC1; GDSC2; CTRP2; CTRP1 5.6159 11.9293 2.0761 11.4076
Calu-1 CTRP2 6.2445 16.5313 0.2679 16.9145
LC-1F CTRP2 6.2602 11.4987 2.7658 7.453
NCI-H1395 CTRP2 6.4258 10.1882 3.5126 4.2089
NCI-H2110 GDSC1; GDSC2; CTRP2; CTRP1 6.4621 12.511 2.4277 8.5725
CAL-12T GDSC1; GDSC2; CTRP2; CTRP1 6.4707 8.8752 4.1592 1.771
RERF-LC-Ad1 CTRP2 6.538 17.0447 -0.4798 14.9093
MOR/CPR CTRP2 6.6323 7.6975 4.6993 0.1198
A-549 GDSC1; GDSC2; CTRP2; CTRP1 6.6883 13.6755 2.0215 9.823
NCI-H1869 GDSC1; GDSC2; CTRP2 6.8644 15.6849 1.1542 12.7557
NCI-H838 GDSC1; GDSC2; CTRP2 6.9306 10.6969 3.5925 3.2796
LK2 CTRP2 7.0085 14.3408 1.9139 9.6798
RERF-LC-MS GDSC1; GDSC2; CTRP2 7.2133 11.1311 3.5622 3.0819
NCI-H460 GDSC1; GDSC2; CTRP2; CTRP1 7.3149 8.5107 4.6774 0.0569
NCI-H1339 CTRP2 7.4342 8.9184 4.5664 0.129
NCI-H647 GDSC1; GDSC2; CTRP2 7.5093 12.672 3.0365 4.6917
KNS-62 GDSC1; GDSC2; CTRP2; CTRP1 7.519 14.4422 2.225 7.8271
RERF-LC-Ad2 CTRP2 7.6197 9.611 4.3901 0.3423
NCI-H292 GDSC1; GDSC2; CTRP2 7.7123 9.2623 4.5474 0.1058
HCC827 GDSC1; GDSC2; CTRP2; CTRP1 7.7709 16.2283 1.5407 10.0361
NCI-H322 CTRP2 7.8119 9.1487 4.6195 0.0427
LXF 289 GDSC1; GDSC2; CTRP2; CTRP1 7.9462 17.1546 1.2152 10.9633
NCI-H661 GDSC1; GDSC2; CTRP2; CTRP1 7.9644 15.4219 2.0526 7.8835
NCI-H196 GDSC1; GDSC2; CTRP2 8.1609 15.2567 2.2429 6.8663
DMS 273 GDSC1; GDSC2; CTRP2; CTRP1 8.3304 16.2827 1.8829 8.0375
NCI-H2126 CTRP2; CTRP1 8.4079 20.0326 0.146 13.9216
HCC1171 CTRP2 8.501 16.5631 1.8477 7.8879
DMS 114 GDSC1; GDSC2; CTRP2 8.587 16.526 1.9188 7.5267
NCI-H2172 GDSC1; GDSC2; CTRP2; CTRP1 8.9408 15.5754 2.5749 4.8675
NCI-H1623 GDSC1; GDSC2; CTRP2 9.2109 16.8488 2.1466 6.012
NCI-H1568 GDSC1; GDSC2; CTRP2; CTRP1 9.7372 21.809 0.188 11.9972
NCI-H1703 GDSC1; GDSC2; CTRP2 9.9535 23.085 -0.2861 13.1172
Hs 888.Lu CTRP2 7.8549 9.7249 4.439 0.2049
⏷ Show the Full List of 227 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1; GDSC2 3.0043 4.4022 2.4987 5.0411
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 -0.0564 4.2372 -0.3245 34.8244
SYO-1 CTRP2 5.6351 13.6654 1.2157 14.6503
H-STS CTRP2 6.0354 11.0774 2.8087 7.6349
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 1.2612 15.7579 -3.7188 40.6107
Cancer Drug Sensitivity Data Curated from 48 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 6.7385 15.084 1.357 12.2109
RMUG-S CTRP1 -1.9126 1.3456 -1.9393 85.3035
JHOM-1 CTRP2; CTRP1 -1.5012 3.6989 -1.7801 44.1832
JHOC-5 CTRP2; CTRP1 -1.3987 0.4922 -1.3997 42.983
OVISE GDSC1; GDSC2; CTRP2 -1.0405 2.2496 -1.0911 40.6825
OAW28 GDSC1; GDSC2; CTRP2 -0.4804 3.9651 -0.7284 37.5349
RMG-I GDSC1; GDSC2; CTRP2; CTRP1 0.2102 5.1545 -0.2591 33.7527
SNU-119 CTRP2 1.087 5.8422 0.4841 28.4256
OV-90 GDSC1; GDSC2; CTRP2; CTRP1 1.28 6.3015 0.5393 27.7043
DOV13 GDSC1; GDSC2; CTRP2 1.4847 3.3732 1.4578 23.8056
OVMANA CTRP1 1.8794 4.3305 1.7573 45.8037
OVCAR-5 GDSC1; GDSC2; CTRP2 1.8964 4.2431 1.7898 21.336
OVKATE GDSC1; GDSC2; CTRP1 1.9783 3.8348 1.9353 22.122
OVCAR-3 GDSC1; GDSC2 2.3724 5.2797 1.4713 12.0055
OC 314 GDSC1; GDSC2; CTRP2 2.548 7.6363 1.3459 21.0804
JHOS-4 GDSC1; GDSC2; CTRP1 2.6899 5.8651 2.2159 18.7174
A2780 GDSC1; GDSC2; CTRP2; CTRP1 2.7617 4.3158 2.7088 15.4687
Caov-4 GDSC1; GDSC2 2.8016 4.7552 2.1361 7.4383
TOV-112D GDSC1; GDSC2; CTRP2 3.1037 7.7089 1.8807 17.5617
OVCAR-4 GDSC1; GDSC2; CTRP2; CTRP1 3.5459 7.1537 2.5845 13.7283
FU-OV-1 GDSC1; GDSC2; CTRP2 3.8496 10.3924 1.3194 17.9365
OV7 CTRP2; CTRP1 3.9527 5.4566 3.7237 8.1879
SNU-840 CTRP2; CTRP1 4.0637 9.2935 2.0641 14.5926
OAW42 GDSC1; GDSC2; CTRP2; CTRP1 4.2236 5.0361 4.1534 5.8041
COV318 CTRP1 4.4155 4.9114 4.3908 9.372
ES-2 GDSC1; GDSC2 4.4388 7.7443 1.958 4.7651
Caov-3 GDSC2; CTRP2; CTRP1 4.5771 11.3402 1.5082 15.6853
EFO-27 GDSC1; GDSC2; CTRP2; CTRP1 4.5798 5.4964 4.3749 3.9533
TYK-nu GDSC1; GDSC2; CTRP2; CTRP1 4.7897 9.4456 2.6373 10.6869
COV362 CTRP2; CTRP1 4.9542 9.4556 2.7727 9.7947
OVCAR-8 GDSC1; GDSC2; CTRP2; CTRP1 5.1162 12.0751 1.5984 14.2417
ES2 CTRP2 6.4677 7.5286 4.6972 0.1645
OV56 GDSC1; GDSC2; CTRP2 6.5978 15.2384 1.177 13.1075
OVK18 GDSC1; GDSC2; CTRP2; CTRP1 6.7063 8.4579 4.4573 0.6327
JHOS-2 GDSC1; GDSC2; CTRP2 6.7996 9.0187 4.2592 1.0902
SNU-8 CTRP2 6.9725 8.2245 4.6398 0.1266
TOV-21G GDSC1; GDSC2; CTRP2 7.0855 13.916 2.1729 8.5671
ONCO-DG-1 CTRP2 7.1259 8.8957 4.4563 0.3903
COV644 CTRP2; CTRP1 7.1486 9.0527 4.4202 0.4955
COV434 CTRP2; CTRP1 7.2727 14.8248 1.8751 9.5045
EFO-21 GDSC1; GDSC2; CTRP2; CTRP1 7.4001 11.5383 3.4996 3.1761
MCAS CTRP2 7.4778 9.3344 4.4353 0.3075
OVTOKO GDSC1; GDSC2; CTRP2 7.6755 11.0713 3.8384 1.7235
IGROV-1 GDSC1; GDSC2; CTRP2; CTRP1 7.7056 9.4263 4.5028 0.1745
Kuramochi GDSC1; GDSC2; CTRP2 8.5705 14.7945 2.6999 4.749
SK-OV-3 GDSC1; GDSC2; CTRP2; CTRP1 9.7083 18.3494 1.772 6.8244
HEY A8 CTRP2; CTRP1 9.8921 18.1491 1.9677 5.9761
OVSAHO CTRP2 13.1406 26.5379 0.0592 8.6426
⏷ Show the Full List of 48 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Aska-SS CTRP2 7.5745 13.7689 2.5673 6.3841
Yamato-SS CTRP2 7.9975 19.8867 -0.0828 15.1952
Rh18 GDSC1; CTRP2 -4.2853 0.8021 -4.3662 61.1551
Rh41 GDSC1; GDSC2; CTRP2 0.3365 7.4772 -0.9151 35.042
RD GDSC1; GDSC2; CTRP2 0.8362 4.2012 0.6516 28.6603
EW-8 GDSC1; GDSC2 1.6676 5.3261 0.7449 17.7099
A-204 GDSC1; GDSC2; CTRP2 2.0519 3.9012 2.0052 20.0941
TE 441.T GDSC2; CTRP2 2.2315 6.3299 1.5478 21.207
G-401 GDSC1; GDSC2; CTRP2; CTRP1 2.2559 4.9854 2.0196 19.479
HT-1080 GDSC1; GDSC2; CTRP2; CTRP1 2.3355 7.6297 1.1349 22.5174
Hs 633.T GDSC1; GDSC2 2.4265 3.7067 2.218 8.2115
KYM-1 GDSC1; GDSC2; CTRP2 2.4776 3.4878 2.4741 17.1119
MFH-ino GDSC1; GDSC2 3.0107 4.5352 2.4397 5.3218
SK-LMS-1 GDSC1; GDSC2; CTRP2 3.0837 6.5021 2.3847 15.6478
GCT GDSC1; GDSC2; CTRP2 3.301 11.6251 0.2081 23.215
G-402 GDSC1; GDSC2; CTRP2 3.4353 8.5842 1.8034 17.0329
STS-0421 GDSC1; GDSC2 4.0811 6.2273 0.3023 0.4096
SW872 GDSC1; GDSC2 4.591 8.4977 1.7 5.7616
MES-SA GDSC1; GDSC2; CTRP2 4.636 5.1089 4.5795 2.9212
Hs 729.T CTRP2 4.6553 5.0961 4.6046 2.7717
TE 617.T CTRP2 4.7087 7.0792 3.7353 6.187
Rh30 GDSC1; GDSC2 4.8944 9.3146 1.513 6.1532
SW684 GDSC1; GDSC2 4.9673 7.9967 2.1717 2.9711
VA-ES-BJ GDSC1; GDSC2 5.5972 10.6983 1.3134 5.9857
BT-16 CTRP2 6.1253 8.4393 4.1409 2.1486
Tm87-16 CTRP2 6.2976 8.2054 4.3456 1.2264
TTC-709 CTRP2 6.3 9.5912 3.7129 3.5865
SW982 GDSC1; GDSC2; CTRP2 6.8704 11.0292 3.4023 4.0695
RKN GDSC1; GDSC2; CTRP2; CTRP1 7.1296 12.3222 2.9739 5.4638
SK-UT-1 GDSC1; GDSC2; CTRP2 8.2378 15.1428 2.3434 6.4042
BT-12 CTRP2 8.2996 17.0245 1.5015 9.3916
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H GDSC1; GDSC2; CTRP2; CTRP1 0.68 7.7367 -0.6469 33.25
MPP 89 GDSC1; GDSC2; CTRP2 1.7697 4.825 1.528 22.6545
NCI-H2052 GDSC1; GDSC2; CTRP2; CTRP1 2.3809 5.0972 2.1258 18.7163
NCI-H28 GDSC1; GDSC2; CTRP2; CTRP1 4.1041 7.2998 3.0691 10.3989
NCI-H2452 GDSC1; GDSC2; CTRP2 6.0221 8.3775 2.5366 0.625
JL-1 CTRP2 6.9213 8.1221 4.6568 0.1156
ACC-MESO-1 CTRP2 7.237 8.5505 4.6225 0.1004
IST-Mes1 GDSC1; GDSC2; CTRP2 7.6788 9.2317 4.5461 0.1119
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H660 GDSC2; CTRP2 -3.7331 -0.6812 -3.7381 58.3901
PC-3 GDSC1; GDSC2 2.8808 4.812 2.1835 6.9764
PaCa-3 CTRP2; CTRP1 4.7862 8.4795 3.1164 8.6969
DU145 GDSC1; GDSC2; CTRP2 5.5139 8.3923 3.7438 4.6246
22Rv1 GDSC1; GDSC2; CTRP2 6.1297 9.5554 3.6167 4.2011
VCaP GDSC1; GDSC2; CTRP2 7.1232 8.9015 4.4529 0.3983
LNCaP clone FGC GDSC1; GDSC2; CTRP2 7.151 12.6232 2.8339 5.9081
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1; GDSC2; CTRP2 3.4355 6.4985 2.7538 13.2636
YD-15 CTRP2 6.0131 7.2099 3.7021 0.1113
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1; GDSC2 2.4597 4.2226 0.3813 1.2097
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 GDSC1; GDSC2; CTRP2 -3.53 -0.0642 -3.5437 56.9935
GSS CTRP2 -2.1337 -0.4332 -2.1338 47.8216
OCUM-1 GDSC1; GDSC2 -1.1142 1.7412 -1.1971 36.4217
SK-GT-2 GDSC1; GDSC2 -1.0733 3.9414 -1.6572 37.7231
RF-48 GDSC1; GDSC2 -1.0004 3.4498 -1.4307 36.7024
AGS GDSC1; GDSC2; CTRP2; CTRP1 -0.2707 4.688 -0.6605 36.6219
KE-39 CTRP2 0.3163 5.9884 -0.401 33.7366
GCIY GDSC1; GDSC2 0.7325 3.5949 0.417 22.43
SNU-1 GDSC1; GDSC2; CTRP2 0.8519 6.8229 -0.1155 31.1039
SNU-16 GDSC1; GDSC2; CTRP2 1.1109 4.0881 0.9698 26.6851
HSC-39 GDSC1; GDSC2 1.1151 2.3555 1.0929 18.0523
SNU-719 CTRP2 1.2048 9.6195 -1.3373 29.5953
NCC-StC-K140 CTRP2 1.2646 5.4718 0.7952 26.8043
HuG1-N CTRP2 1.6435 4.5308 1.4595 23.2904
MKN74 CTRP2; CTRP1 1.7236 5.7697 1.2027 24.0327
HGC-27 GDSC1; GDSC2; CTRP2 2.006 3.1925 2.0021 20.2555
SCH GDSC1; GDSC2 2.1932 3.7205 0.4584 1.1526
MKN7 GDSC1; GDSC2; CTRP2; CTRP1 2.4333 5.5661 2.0405 18.8703
MKN1 GDSC1; GDSC2 2.471 4.8381 1.7751 10.2067
RERF-GC-1B GDSC1; GDSC2 2.68 7.462 0.6953 14.9977
MKN28 GDSC1; GDSC2 3.0907 5.7375 1.9165 7.7809
TMK-1 GDSC1; GDSC2 3.1174 4.8337 0.433 0.5046
NCI-N87 GDSC1; GDSC2; CTRP2 3.3177 11.9956 0.0424 23.718
Hs 746.T GDSC1; GDSC2; CTRP2 3.4162 7.4625 2.3072 15.0808
SNU-620 CTRP2 4.267 11.2991 1.2477 17.2771
SNU-5 GDSC1; GDSC2; CTRP2 4.3424 10.9217 0.8804 13.7029
SNU-216 CTRP2 4.374 9.5345 2.2188 13.2029
TGBC11TKB GDSC1; GDSC2 4.7084 8.8601 1.6057 6.0189
NUGC-4 GDSC1; GDSC2; CTRP2; CTRP1 5.7721 15.8902 0.2255 17.9739
GSU CTRP2 5.9695 6.6328 4.8282 0.0917
MKN45 GDSC1; GDSC2; CTRP2 6.1466 7.1961 4.6902 0.3018
SNU-668 CTRP2 6.2298 7.4595 3.6935 0.0857
IM95 GDSC1; GDSC2; CTRP2 6.2559 9.7172 3.6241 3.9961
SH-10-TC CTRP2; CTRP1 6.5333 11.3119 3.0595 5.9355
ECC12 GDSC2; CTRP2 6.7423 7.9857 4.6382 0.1831
SNU-601 CTRP2 7.1366 13.8318 2.2484 8.2013
23132/87 GDSC1; GDSC2; CTRP2 7.1994 8.7959 4.5223 0.2431
KATO III GDSC1; GDSC2; CTRP2 7.6631 9.931 4.2889 0.5234
Fu97 GDSC1; GDSC2; CTRP2; CTRP1 7.7191 14.3755 2.3871 6.9485
NUGC-3 GDSC1; GDSC2; CTRP2 7.8841 16.2931 1.5743 9.6904
LMSU CTRP2 8.6826 14.9577 2.6909 4.6653
SNG-M GDSC1; GDSC2; CTRP2; CTRP1 1.8331 5.8002 1.3114 23.3137
SNU-685 CTRP2 6.8965 8.6866 4.4388 0.5319
SNU-1077 CTRP2 9.0512 19.0644 1.0261 10.077
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
FTC-133 GDSC1; GDSC2 1.0742 4.826 -0.0776 16.959
B-CPAP GDSC1; GDSC2; CTRP2 1.9889 5.4907 1.5781 21.8069
ML-1 [Human leukemia] GDSC1; GDSC2; CTRP2 2.039 4.7447 -0.0934 4.0164
HTC-C3 GDSC1; GDSC2 2.2048 6.1266 0.9066 15.2871
IHH-4 GDSC1; GDSC2 2.5994 3.9154 2.3185 7.1563
ASH-3 GDSC1; GDSC2 2.8274 3.5817 2.6943 4.6188
K5 GDSC1; GDSC2 2.9343 4.3053 2.479 5.3385
KMH-2 GDSC1; GDSC2 2.9376 4.9837 0.2982 1.0992
8505C GDSC1; GDSC2; CTRP2 3.5751 8.6723 1.8967 16.3243
WRO GDSC1; GDSC2 3.7884 8.4332 1.1438 10.0907
CAL-62 GDSC1; GDSC2; CTRP2 4.1713 7.2589 3.1459 9.8419
SW579 CTRP2 4.6465 5.0183 4.6169 2.7537
BHT-101 GDSC1; GDSC2; CTRP2 5.7135 13.947 0.4385 12.9167
TT2609-C02 GDSC1; GDSC2; CTRP2 6.3046 14.3446 1.3982 12.7753
8305C GDSC1; GDSC2; CTRP2 7.3615 12.3531 3.0931 4.653
FTC-238 CTRP2 7.4256 13.269 2.7068 6.0424
CGTH-W-1 GDSC1; GDSC2; CTRP2 7.4734 8.9629 4.5652 0.1238
TT GDSC1; GDSC2; CTRP2 9.8054 21.0942 0.5553 10.6939
⏷ Show the Full List of 18 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BICR 56 CTRP2 -0.6546 5.6274 -1.3435 39.6805
SCC-4 GDSC1; GDSC2; CTRP2 0.3851 5.7791 -0.2585 33.0856
DOK GDSC1; GDSC2 1.3878 4.5073 0.8007 18.3677
BB49-HNC GDSC1; GDSC2 1.5132 2.6604 1.4815 17.6791
HO-1-u-1 GDSC1; GDSC2 1.6073 3.4004 1.4288 14.7209
BICR 10 GDSC1; GDSC2 1.9138 5.396 0.9625 15.8904
JHU-029 GDSC1; GDSC2 1.9301 6.5056 -1.0214 10.2237
Ca9-22 GDSC1; GDSC2 2.0011 4.1768 1.582 12.6343
PCI-06A GDSC1; GDSC2 2.1219 7.0878 -1.167 10.6153
BB30-HNC GDSC1; GDSC2 2.3505 10.9418 -2.8951 18.8893
HO-1-N-1 GDSC1; GDSC2 2.4115 3.5798 2.2477 8.1274
OSC-19 GDSC1; GDSC2 2.4454 7.6827 -1.2269 10.2118
PCI-15A GDSC1; GDSC2 2.5204 13.7909 -4.1768 23.4022
PCI-30 GDSC1; GDSC2 2.5272 4.2551 2.0971 8.4549
SAS GDSC1; GDSC2 2.5611 4.2972 2.1128 8.2717
PCI-38 GDSC1 2.5632 9.2726 -1.9169 16.2935
LB771-HNC GDSC1; GDSC2 2.6605 5.3437 1.718 9.9402
KOSC-2 GDSC1; GDSC2 2.6778 7.9356 -1.1888 9.4885
OSC-20 GDSC1; GDSC2 2.7654 4.2504 2.3395 6.531
BICR 78 GDSC1; GDSC2 2.8261 4.4973 2.283 6.6316
SCC-15 GDSC1; GDSC2 2.8651 7.1085 1.0357 12.829
NCI-H3118 GDSC1; GDSC2 3.0959 8.9146 0.3351 15.6529
UPCI-SCC-090 GDSC1; GDSC2 3.437 10.572 -0.2076 17.2809
SNU-1214 CTRP2 3.5717 9.2345 1.0725 14.5426
HSC-2 GDSC1; GDSC2; CTRP2; CTRP1 3.7195 9.6311 1.579 17.3082
KON GDSC1; GDSC2 3.9651 13.0034 -2.7467 14.6168
BICR 22 GDSC1; GDSC2; CTRP2 4.1036 12.2972 0.607 19.9865
SCC-25 GDSC1; GDSC2; CTRP2 4.2324 10.4843 1.6213 15.9079
FaDu GDSC1; GDSC2; CTRP2 4.4061 4.9361 4.3741 4.3622
CAL-33 GDSC1; GDSC2; CTRP2 4.4513 11.0615 1.5284 15.7996
YD-8 CTRP2 4.6689 5.2199 4.5762 2.8386
PE/CA-PJ41 (clone D2) CTRP2 4.686 6.2932 4.1009 4.7164
PCI-04B GDSC1; GDSC2 4.7677 13.7454 -2.5731 12.3295
PE/CA-PJ15 GDSC1; GDSC2; CTRP2 4.8403 6.9729 3.9052 5.1973
JHU-022 GDSC1; GDSC2 5.455 12.7338 0.2532 11.0371
SAT [Human HNSCC] GDSC1; GDSC2 5.5563 14.7215 -0.6401 14.6135
BHY GDSC1; GDSC2; CTRP2 5.7572 11.6136 2.3333 10.0433
SNU-46 CTRP2 5.866 7.8683 3.3933 0.8613
SKN-3 GDSC1; GDSC2 5.9277 10.3497 1.6686 3.9558
JHU-011 GDSC1; GDSC2 6.0723 16.6072 -3.0909 12.2928
SNU-899 CTRP2 6.2851 7.7331 3.619 0.1641
YD-10B CTRP2 6.3637 7.784 3.6299 0.134
BICR 6 CTRP2 6.8629 8.2214 4.5997 0.2119
PE/CA-PJ49 CTRP2 6.9731 10.5914 3.6656 2.9621
PE/CA-PJ34 (clone C12) CTRP2 6.987 11.3875 3.3086 4.2859
CAL-27 GDSC1; GDSC2; CTRP2 7.0491 8.4121 4.6023 0.1601
Detroit 562 GDSC1; GDSC2; CTRP2 7.1463 11.2121 3.4862 3.4319
BICR 18 CTRP2 7.2818 13.2848 2.6064 6.6155
SNU-1076 CTRP2 7.3446 12.5689 2.9826 5.0919
BICR 16 CTRP2 7.4819 11.194 3.6847 2.387
SNU-1066 CTRP2 8.0619 9.4047 4.6186 0.0291
SNU-1041 CTRP2 8.2079 16.7032 1.5937 9.1813
HSC-4 GDSC2; CTRP2 8.4983 15.7196 2.2369 6.4853
SCC-9 GDSC1; GDSC2; CTRP2; CTRP1 8.5077 15.8431 2.198 6.678
HSC-3 GDSC1; GDSC2; CTRP2 9.6768 21.1926 0.4273 11.2624
BICR 31 GDSC2; CTRP2 9.7837 21.9592 0.1354 12.0481
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KMBC-2 CTRP2; CTRP1 -2.0223 2.1309 -2.1095 47.2373
U-BLC1 CTRP2 0.1486 1.6779 0.1473 32.6208
RT-4 GDSC1; GDSC2; CTRP2; CTRP1 1.6684 4.0125 1.583 22.8558
TCCSUP GDSC1; GDSC2; CTRP2 1.8144 3.5401 1.7891 21.6034
HT-1376 GDSC1; GDSC2; CTRP2; CTRP1 1.9915 4.3492 1.875 20.8138
5637 GDSC1; GDSC2; CTRP2; CTRP1 2.434 5.6959 1.998 19.0252
T24 GDSC1; GDSC2; CTRP2 2.907 8.4879 1.3278 20.1985
BC-3C CTRP2 2.9637 7.8826 1.6608 18.7786
HT-1197 GDSC1; GDSC2; CTRP2 3.0204 5.428 2.72 14.5534
UM-UC-1 CTRP2 4.2646 9.2809 2.2457 13.331
253J-BV CTRP2 4.3018 6.3153 3.7187 7.1934
BFTC-905 GDSC1; GDSC2 4.3307 7.6394 1.9351 5.0633
UM-UC-3 GDSC1; GDSC2; CTRP2; CTRP1 4.6188 9.345 2.5389 11.4465
CAL-29 GDSC1; GDSC2; CTRP2 4.7395 7.2645 3.671 6.3898
SW780 GDSC1; GDSC2 5.5407 9.0387 2.0322 2.8706
SW1710 GDSC1; GDSC2; CTRP2 6.2535 11.8313 2.5982 8.1421
JMSU-1 CTRP2 6.4787 8.5013 4.3142 1.1717
639V GDSC1; GDSC2; CTRP2 6.4944 7.4754 4.7263 0.1134
RT-112 GDSC1; GDSC2; CTRP2 6.5073 14.1149 1.6631 11.4293
KU-19-19 GDSC1; GDSC2; CTRP2 6.7185 7.6856 4.7344 0.0647
647V GDSC1; GDSC2; CTRP2 6.9333 8.348 4.5812 0.2224
SCaBER CTRP2 7.2286 15.0637 1.7176 10.0979
J82 GDSC1; GDSC2; CTRP2 7.3964 9.885 4.1905 0.8911
VM-CUB-1 CTRP2 7.9498 11.4717 3.8076 1.6144
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TC-YIK GDSC1; GDSC2 -2.8931 -1.3679 -2.8933 50.5823
NT2-D1 GDSC1; GDSC2 -0.6854 2.539 -0.8652 33.3264
SW954 GDSC1; GDSC2 0.6235 13.7122 -5.6725 32.4575
HEC-1 GDSC1; GDSC2 0.7129 5.6471 -0.3786 25.9664
BPH-1 GDSC1; GDSC2 1.0739 5.0218 0.2608 21.9214
PA-1 GDSC1; GDSC2 1.3789 4.6961 0.7151 18.7964
UWB1.289 GDSC1; GDSC2 1.5205 4.0897 -0.1354 5.8084
OMC-1 [Human cervical carcinoma] GDSC1; GDSC2 1.5219 4.0731 -0.1262 5.7478
CAL-39 GDSC1; GDSC2 1.6629 3.8894 1.3299 14.968
JEG-3 GDSC1; GDSC2 1.7062 6.3014 -1.0876 11.1739
OVMIU GDSC1; GDSC2 1.7372 6.9836 0.0467 20.7512
C-4-I GDSC1; GDSC2 1.7716 3.5584 1.56 13.5343
LB831-BLC GDSC1; GDSC2 1.8075 4.1849 1.3736 14.2665
DoTc2 4510 GDSC1; GDSC2 1.8634 4.7602 1.194 14.9337
JHOS-3 GDSC1; GDSC2 2.1846 5.7497 -0.475 6.3874
ACC-OV7 GDSC1; GDSC2 2.2463 15.1207 -5.0505 26.7415
Ca Ski GDSC1; GDSC2 2.3931 6.185 1.058 13.9984
DSH1 GDSC1; GDSC2 2.4291 5.3885 1.4749 11.8208
SKN GDSC1; GDSC2 2.5005 4.2119 2.0888 8.5795
SW756 GDSC1; GDSC2 2.6116 5.2233 1.7295 10.0213
NCC-IT GDSC2 2.6263 4.9849 1.8578 9.337
C-33 A GDSC1; GDSC2 2.6692 4.5014 2.1277 7.8674
OV17R GDSC1; GDSC2 2.8723 5.0945 0.2225 1.4802
JAR GDSC1; GDSC2 2.9172 4.2931 0.5515 0.2875
OVCA420 GDSC1; GDSC2 3.1359 4.9429 2.3516 5.4391
SW962 GDSC1; GDSC2 3.148 5.4511 0.208 1.2745
KGN GDSC1; GDSC2 3.3989 5.3511 2.3707 4.7058
SiHa GDSC1; GDSC2 3.4318 5.6007 2.2727 5.1341
HT-3 GDSC1; GDSC2 3.5597 6.35 2.0012 6.2409
OVCA433 GDSC1; GDSC2 3.6316 5.4136 0.4222 0.3112
PEO1 GDSC1; GDSC2 3.7533 7.6887 1.4868 8.4419
PWR-1E GDSC1; GDSC2 3.8382 6.5279 2.1262 5.0244
MS751 GDSC1; GDSC2 3.8659 6.3144 2.2513 4.3399
ME-180 GDSC1; GDSC2 3.9598 14.3165 -1.6532 21.6868
SiSo GDSC1; GDSC2 4.5334 6.8944 2.4158 2.4535
SKG-IIIa GDSC1; GDSC2 5.0868 8.4578 2.0331 3.4323
HEY GDSC1; GDSC2 5.3711 7.7367 2.4983 1.2176
NEC8 GDSC1; GDSC2 5.7445 12.9426 0.35 10.1077
HeLa GDSC1; GDSC2; CTRP2 6.685 7.6884 4.7216 0.0826
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

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