Details of the Drug

General Information of Drug (ID: DMNG35S)

Drug Name
ABT-751
Synonyms
ABT-751; 141430-65-1; ABT 751; E-7010; ABT751; ABT-751 (E7010); UNII-WDT5V5OB9F; E 7010; WDT5V5OB9F; N-[2-[(4-HYDROXYPHENYL)AMINO]-3-PYRIDYL]-4-METHOXYBENZENESULFONAMIDE; CHEMBL20684; N-(2-((4-Hydroxyphenyl)amino)-3-pyridinyl)-4-methoxybenzenesulfonamide; N-{2-[(4-hydroxyphenyl)amino]pyridin-3-yl}-4-methoxybenzenesulfonamide; Benzenesulfonamide,N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxy-; N-(2-(4-hydroxyphenylamino)pyridin-3-yl)-4-methoxybenzenesulfonamide
Indication
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 2 [1]
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 371.4
Logarithm of the Partition Coefficient (xlogp) 2.8
Rotatable Bond Count (rotbonds) 6
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 7
Chemical Identifiers
Formula
C18H17N3O4S
IUPAC Name
N-[2-(4-hydroxyanilino)pyridin-3-yl]-4-methoxybenzenesulfonamide
Canonical SMILES
COC1=CC=C(C=C1)S(=O)(=O)NC2=C(N=CC=C2)NC3=CC=C(C=C3)O
InChI
InChI=1S/C18H17N3O4S/c1-25-15-8-10-16(11-9-15)26(23,24)21-17-3-2-12-19-18(17)20-13-4-6-14(22)7-5-13/h2-12,21-22H,1H3,(H,19,20)
InChIKey
URCVCIZFVQDVPM-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
3035714
ChEBI ID
CHEBI:95043
CAS Number
141430-65-1
UNII
WDT5V5OB9F
DrugBank ID
DB12254
TTD ID
D09EHO
INTEDE ID
DR1853
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tubulin beta (TUBB) TTYFKSZ NOUNIPROTAC Modulator [2]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
UDP-glucuronosyltransferase 1A1 (UGT1A1) DEYGVN4 UD11_HUMAN Substrate [3]
Sulfotransferase 1B1 (SULT1B1) DED5UR3 ST1B1_HUMAN Substrate [3]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U2OS CTRP1 3.8642 13.9644 -0.4249 38.2486
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MCF-7 CTRP1 1.8262 17.3283 -3.9416 49.072
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
GaMG CTRP1 -1.0014 10.3333 -3.4829 61.7369
SF295 CTRP1 0.0314 27.9275 -10.7948 52.9848
LN-229 CTRP1 1.4153 7.8435 0.0851 51.0989
Cancer Drug Sensitivity Data Curated from 10 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HEC-265 CTRP1 -4.9475 8.0968 -6.8195 74.4183
HEC-108 CTRP1 -3.6092 7.8387 -5.283 72.2851
HEC-251 CTRP1 -2.8044 22.553 -10.872 59.2719
HEC-151 CTRP1 -2.2139 9.2962 -4.3344 66.7198
KLE CTRP1 -1.8342 20.1172 -8.775 58.3268
JHUEM-2 CTRP1 -1.6733 8.865 -3.5904 65.6211
MFE-319 CTRP1 -1.5439 1.567 -1.5703 83.1319
HEC-6 CTRP1 2.472 42.8316 -16.0243 48.7609
HEC-59 CTRP1 6.9646 19.0048 -0.3966 27.7574
Ishikawa (Heraklio) 02 ER- CTRP1 -1.747 -1.0571 -1.747 95.2896
⏷ Show the Full List of 10 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AMO1 CTRP1 -3.2874 5.501 -4.1741 75.8889
BL-70 CTRP1 -2.5027 -1.1172 -2.5027 96.9004
KE-97 CTRP1 -2.3129 0.1543 -2.316 91.3384
SKM-1 CTRP1 -1.9482 -0.9894 -1.9482 95.7297
EJM CTRP1 -1.9316 3.6556 -2.2378 77.0054
MOLM-16 CTRP1 -1.7506 -0.0709 -1.7508 90.9867
RPMI-8226 CTRP1 -1.4813 0.4341 -1.4823 87.6626
WSU-DLCL2 CTRP1 -1.4601 -0.8532 -1.4601 92.4919
OCI-AML-3 CTRP1 -1.1198 -0.0713 -1.1198 87.1457
MC116 CTRP1 -1.0078 -0.3365 -1.0078 86.4607
NU-DUL-1 CTRP1 -0.9667 0.355 -0.9667 84.5281
Ku812 CTRP1 -0.9488 0.1609 -0.9488 84.8732
HT CTRP1 -0.9253 1.6653 -0.9399 79.6539
U-937 CTRP1 -0.7827 0.9307 -0.7836 81.1844
LP-1 CTRP1 -0.7213 8.4859 -2.43 62.6024
NOMO-1 CTRP1 -0.2772 0.6317 -0.2772 76.1246
THP-1 CTRP1 -0.2581 5.6909 -0.9279 64.4087
P3HR-1 CTRP1 0.301 1.8065 0.2997 67.6104
PL21 CTRP1 0.3698 1.6568 0.3694 66.8292
SU-DHL-4 CTRP1 0.6881 2.1941 0.6858 62.2474
GDM-1 CTRP1 1.0712 2.5447 1.0677 56.8856
KMS-11 CTRP1 1.7067 3.532 1.6778 47.9504
OCI-Ly10 CTRP1 1.9462 6.0992 1.3302 45.9745
SU-DHL-5 CTRP1 3.0134 4.3452 2.9733 29.5099
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
VMRC-RCW CTRP1 7.4083 26.2027 -3.6246 33.7417
RCC10RGB CTRP1 9.6384 26.4601 -2.1072 26.1387
Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LS180 CTRP1 -4.5535 7.2845 -6.1137 75.0188
SNU-175 CTRP1 -1.3346 2.3437 -1.4065 79.22
LoVo CTRP1 -0.5043 4.8552 -0.958 67.485
HT115 CTRP1 -0.1706 0.9274 -0.1706 74.504
RKO CTRP1 -0.0485 1.4837 -0.0494 72.3297
HCT 116 CTRP1 0.0552 2.2569 0.0417 69.7476
NCI-H508 CTRP1 0.2627 4.0932 0.0531 63.8627
SNU-C4 CTRP1 0.3776 4.4598 0.1003 62.232
KM12 CTRP1 0.3859 6.0203 -0.3324 59.8273
MDST8 CTRP1 0.795 6.0152 0.1133 56.8075
SNU-C5 CTRP1 1.1678 5.8138 0.5847 53.7889
SNU-81 CTRP1 1.4554 4.9218 1.1629 51.1881
CL-34 CTRP1 1.5396 4.7648 1.2943 50.2289
SW948 CTRP1 1.6313 2.9132 1.628 48.9708
SNU-1040 CTRP1 1.6904 7.4744 0.526 48.908
SNU-C2A CTRP1 2.1406 8.0676 0.7444 45.2671
HT-55 CTRP1 2.5936 8.134 1.1791 41.2021
CW-2 CTRP1 2.7591 5.8284 2.3037 35.6927
HCT 8 CTRP1 2.9386 9.98 0.6663 40.3056
SNU-61 CTRP1 3.3417 7.1247 2.3904 31.1356
COLO 320 CTRP1 3.4237 7.4641 2.3205 31.0211
CL-40 CTRP1 4.8993 6.6483 4.1275 9.0776
HT-29 CTRP1 5.73 12.1238 2.0689 21.4206
COLO 678 CTRP1 6.3613 10.9009 3.1392 12.072
RCM-1 [Human ESC] CTRP1 7.5478 17.8161 0.6168 22.6022
LS123 CTRP1 8.1092 21.0804 -0.574 25.3341
SW480 CTRP1 9.1947 25.6764 -2.0395 26.8697
SW620 CTRP1 9.4061 35.4876 -6.7019 34.1525
SW403 CTRP1 9.765 22.8077 -0.2665 20.6089
⏷ Show the Full List of 29 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 4 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-398 CTRP1 -1.7509 8.0016 -3.3424 67.0566
SNU-449 CTRP1 3.8938 26.6586 -6.7266 44.4412
JHH-6 CTRP1 5.5603 7.9327 4.0154 7.5067
Hep-G2 CTRP1 6.9638 8.313 4.6196 0.3858
Cancer Drug Sensitivity Data Curated from 84 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H1048 CTRP1 -5.5778 9.6319 -8.0548 73.3249
VMRC-LCD CTRP1 -5.5218 2.5661 -5.9156 86.0247
Calu-6 CTRP1 -4.404 12.4979 -7.9445 68.1924
LCLC-97TM1 CTRP1 -3.4889 5.9683 -4.5329 75.3539
NCI-H1876 CTRP1 -3.3758 8.8008 -5.3833 70.3415
NCI-H2286 CTRP1 -3.2549 10.9986 -6.1196 67.3763
SHP-77 CTRP1 -2.9375 0.4466 -2.9546 90.8549
KNS-62 CTRP1 -2.5923 11.6368 -5.691 65.1648
NCI-H1792 CTRP1 -2.5381 5.1689 -3.2622 74.7878
LC-1/sq-SF CTRP1 -1.9146 6.0268 -2.8363 71.0216
LXF 289 CTRP1 -1.91 14.0384 -6.0368 61.5144
ChaGo-K-1 CTRP1 -1.6963 10.0645 -4.0975 64.2881
NCI-H841 CTRP1 -1.6755 2.0508 -1.7382 81.6881
DMS 273 CTRP1 -1.6575 7.7267 -3.1402 67.1528
COR-L279 CTRP1 -1.6203 3.1634 -1.814 77.4778
COLO 668 CTRP1 -1.6138 9.4636 -3.7657 64.6992
NCI-H82 CTRP1 -1.5946 1.3185 -1.6121 84.3575
NCI-H1299 CTRP1 -1.5735 12.8091 -5.1466 61.4818
HCC4006 CTRP1 -1.3003 14.1911 -5.4895 59.8089
NCI-H2081 CTRP1 -1.1312 15.9531 -6.1307 58.4265
HARA [Human squamous cell lung carcinoma] CTRP1 -1.0378 13.8134 -5.0538 59.2877
SCLC-21H CTRP1 -0.931 2.9034 -1.0403 75.2676
EPLC-272H CTRP1 -0.8445 29.9039 -12.5713 54.2607
COLO 699 CTRP1 -0.7142 22.6793 -8.9277 55.2705
NCI-H2122 CTRP1 -0.669 2.2835 -0.7064 75.802
HCC2108 CTRP1 -0.6665 31.5458 -13.2138 53.7698
NCI-H1568 CTRP1 -0.6603 1.5032 -0.6662 78.353
NCI-H810 CTRP1 -0.6555 10.293 -3.1062 60.5202
NCI-H596 CTRP1 -0.6052 4.0041 -0.8697 70.1403
COR-L51 CTRP1 -0.6022 142.0169 -68.1931 50.8321
LCLC-103H CTRP1 -0.5662 9.5634 -2.7052 60.833
NCI-H2029 CTRP1 -0.5049 8.7479 -2.3057 61.3984
NCI-H23 CTRP1 -0.2676 2.9268 -0.3403 70.9076
NCI-H1694 CTRP1 0.081 7.3622 -1.1395 60.0888
HCC15 CTRP1 0.1073 26.5035 -10.0257 52.9959
HCC33 CTRP1 0.3431 5.4492 -0.1992 60.9121
HCC44 CTRP1 0.3648 15.7153 -4.5524 54.1755
NCI-H1437 CTRP1 0.6148 2.1174 0.6127 63.2681
HCC1359 CTRP1 0.6602 6.4926 -0.1974 57.3721
NCI-H1836 CTRP1 0.7253 7.024 -0.3221 56.4517
NCI-H2009 CTRP1 1.1844 10.8752 -1.4829 52.0156
NCI-H1963 CTRP1 1.204 4.8653 0.9032 53.9582
NCI-H661 CTRP1 1.3084 9.4301 -0.7071 51.5761
NCI-H1930 CTRP1 1.628 7.7359 0.3527 49.4476
DV-90 CTRP1 1.7304 7.6102 0.5121 48.5915
A-549 CTRP1 1.8948 6.6769 1.0602 46.8037
NCI-H1781 CTRP1 1.9275 5.9426 1.3651 46.0918
CAL-12T CTRP1 2.3794 10.6052 -0.1735 44.9046
NCI-H2126 CTRP1 2.5167 51.1339 -20.13 48.92
HCC1833 CTRP1 2.5924 17.0661 -3.1065 46.1746
Lu-65 CTRP1 2.7367 11.4425 -0.2275 43.0578
COR-L23 CTRP1 2.9623 8.0946 1.5698 37.5009
NCI-H2073 CTRP1 3.0277 18.4876 -3.4152 44.9034
NCI-H727 CTRP1 3.0961 14.0112 -1.1425 42.62
NCI-H1975 CTRP1 3.1046 7.49 1.9862 34.82
NCI-H2141 CTRP1 3.2608 21.945 -4.9258 45.0817
COR-L88 CTRP1 3.5339 38.7691 -13.0834 46.9367
NCI-H1435 CTRP1 3.7926 14.2464 -0.6286 38.9416
NCI-H1944 CTRP1 3.9415 8.7288 2.226 28.5423
NCI-H1105 CTRP1 3.9777 35.0001 -10.822 45.749
NCI-H1355 CTRP1 4.0874 31.3217 -8.8906 44.9503
NCI-H460 CTRP1 4.0936 10.5588 1.4681 31.5086
Sq-1 CTRP1 4.6246 11.0732 1.6826 28.0248
Calu-3 CTRP1 5.054 13.0655 1.0515 29.0028
NCI-H2030 CTRP1 5.1905 14.9898 0.2027 31.5019
NCI-H1755 CTRP1 5.416 15.558 0.1039 31.0106
NCI-H2110 CTRP1 5.4477 8.775 3.5141 12.2319
BEN CTRP1 5.5503 11.4154 2.2803 20.8452
NCI-H2342 CTRP1 5.5689 9.6536 3.1715 14.5506
T3M-10 CTRP1 5.6572 23.9467 -3.8911 38.0986
NCI-H2405 CTRP1 5.7682 23.4682 -3.5616 37.4102
RERF-LC-KJ CTRP1 5.7906 19.5854 -1.604 34.1256
NCI-H650 CTRP1 6.0021 17.0211 -0.1556 29.8671
NCI-H2172 CTRP1 6.6811 15.8442 0.9513 23.7308
NCI-H1666 CTRP1 6.7121 14.7572 1.509 21.0644
SK-LU-1 CTRP1 6.7497 21.8678 -1.9814 32.3172
HCC2935 CTRP1 7.0165 16.2458 1.0011 22.5033
NCI-H1915 CTRP1 7.1259 20.0998 -0.8161 28.539
NCI-H441 CTRP1 7.2259 12.6787 2.8681 11.5007
NCI-H3255 CTRP1 7.2641 9.0661 4.463 0.7701
HCC827 CTRP1 7.4119 22.6815 -1.8765 30.4538
NCI-H1573 CTRP1 7.8964 27.2144 -3.7521 32.9189
NCI-H2023 CTRP1 9.3936 19.8859 0.8715 17.0451
HCC1195 CTRP1 9.8435 21.2753 0.5069 17.596
⏷ Show the Full List of 84 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-410 CTRP1 -0.1305 7.8042 -1.5347 60.7011
KYSE-140 CTRP1 2.4951 25.4763 -7.358 47.7838
KYSE-450 CTRP1 2.7633 10.7881 0.1118 42.3875
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHOS-4 CTRP1 -3.7024 27.098 -13.9045 59.2278
OVCAR-8 CTRP1 -2.5841 2.7115 -2.7783 81.8371
JHOM-1 CTRP1 -1.8772 18.0757 -7.8564 59.2382
OVK18 CTRP1 -1.2024 5.8402 -2.0026 68.7531
A2780 CTRP1 -0.9549 6.9259 -2.0945 65.7405
OVCAR-4 CTRP1 -0.9503 14.3396 -5.2061 58.7405
OVKATE CTRP1 -0.3709 7.6553 -1.7342 62.0574
RMUG-S CTRP1 0.2306 11.8863 -2.9019 56.014
TYK-nu CTRP1 0.242 13.3007 -3.5392 55.3647
RMG-I CTRP1 1.7984 13.3949 -2.0625 48.9053
OV-90 CTRP1 1.9879 9.8442 -0.2065 47.2218
HEY A8 CTRP1 2.4521 17.4175 -3.4078 46.7952
OAW42 CTRP1 2.6102 8.5241 1.0203 41.4854
COV644 CTRP1 2.7928 7.1935 1.7957 37.7991
SK-OV-3 CTRP1 2.9874 22.4179 -5.4021 46.0211
COV434 CTRP1 3.8789 13.3203 -0.0922 37.4604
Caov-3 CTRP1 4.0645 15.6865 -1.1047 38.7597
IGROV-1 CTRP1 5.3873 14.0417 0.8381 28.5689
SNU-840 CTRP1 5.5566 16.564 -0.2843 31.681
JHOC-5 CTRP1 5.6574 34.5887 -9.2102 42.3246
EFO-21 CTRP1 5.8288 12.7705 1.8244 22.4154
COV362 CTRP1 5.8636 25.449 -4.4735 38.2975
OVMANA CTRP1 7.4475 17.8393 0.5335 23.2048
OV7 CTRP1 7.8079 18.5565 0.4412 22.5976
EFO-27 CTRP1 8.4273 30.8933 -5.1698 33.9509
COV318 CTRP1 9.7868 18.3207 1.8306 11.7421
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuP-T4 CTRP1 0.7799 62.4548 -27.2785 50.6926
Capan-2 CTRP1 1.0011 4.8945 0.6743 56.0029
QGP-1 CTRP1 1.0757 46.9236 -19.279 50.5773
KP-3 CTRP1 1.6818 26.4918 -8.5874 49.7294
Panc 03.27 CTRP1 2.9139 12.3428 -0.4954 42.5677
SUIT-2 CTRP1 3.8871 18.3759 -2.5997 41.4565
PaTu 8902 CTRP1 5.0582 22.2825 -3.5535 39.1916
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MSTO-211H CTRP1 -1.8571 2.2943 -1.9518 81.3674
NCI-H28 CTRP1 2.791 6.5676 2.055 36.695
NCI-H2052 CTRP1 7.3712 16.0461 1.3527 19.8663
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
PaCa-3 CTRP1 -3.962 28.9985 -15.0642 59.0583
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Hs 852.T CTRP1 -0.5344 7.3014 -1.7767 63.2958
G-361 CTRP1 -0.4254 17.3294 -6.085 56.0154
Hs 936.T CTRP1 0.5026 16.7072 -4.8925 53.5084
A-375 CTRP1 0.6245 5.4768 0.0992 58.7334
SK-MEL-5 CTRP1 0.6652 10.6436 -1.9023 54.677
Hs 944.T CTRP1 2.4168 14.3378 -1.932 46.1847
SK-MEL-1 CTRP1 4.3936 17.5395 -1.7441 38.6758
SK-MEL-28 CTRP1 6.3614 7.2145 4.783 0.1904
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-401 CTRP1 -3.6359 8.3244 -5.4863 71.6011
RKN CTRP1 -1.8189 5.9443 -2.7063 70.869
HT-1080 CTRP1 -0.5559 4.8862 -1.0224 67.7032
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AGS CTRP1 -1.2427 5.3246 -1.8926 70.0181
SH-10-TC CTRP1 -0.0704 16.0483 -5.1331 55.4275
NUGC-4 CTRP1 0.1334 5.2668 -0.3747 62.6844
Fu97 CTRP1 4.805 15.7908 -0.5201 34.8692
MKN74 CTRP1 7.8518 39.6311 -9.9584 39.3403
MKN7 CTRP1 8.4728 17.8805 1.2213 17.5987
SNG-M CTRP1 -4.868 9.8702 -7.3849 71.8768
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HSC-2 CTRP1 -2.7969 4.4157 -3.3477 77.3083
SCC-9 CTRP1 0.6678 44.1716 -18.2674 51.1221
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
5637 CTRP1 -1.8992 8.109 -3.5414 67.3774
RT-4 CTRP1 -1.1872 6.0983 -2.0675 68.1781
UM-UC-3 CTRP1 2.3292 13.2543 -1.4886 46.2848
HT-1376 CTRP1 5.3953 32.0967 -8.1807 42.2245
KMBC-2 CTRP1 10.119 24.1308 -0.6614 21.1879

References

1 ClinicalTrials.gov (NCT00436852) ABT-751 in Treating Children With Neuroblastoma That Has Relapsed or Not Responded to Previous Treatment. U.S. National Institutes of Health.
2 Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41.
3 Preclinical discovery of candidate genes to guide pharmacogenetics during phase I development: the example of the novel anticancer agent ABT-751. Pharmacogenet Genomics. 2013 Jul;23(7):374-81.