Details of the Drug

General Information of Drug (ID: DMNLQHK)

• Drug Name: Tanespimycin
• Synonyms: CNF-101; [(3S,5S,6R,7S,8E,10R,11S,12E,14E)-6-Hydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-21-(prop-2-enylamino)-17-azabicyclo[16.3.1]docosa-8,12,14,18,21-pentaen-10-yl] carbamate; [(3R,5S,6R,7S,8E,10S,11S,12Z,14E)-6-hydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-21-(prop-2-enylamino)-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate; 17AAG, Tanespimycin, Geldanamycin, NSC330507, 17-(Allylamino)-17-demethoxygeldanamycin, CP 127374

Indication

Disease Entry	ICD 11	Status	REF
Breast cancer	2C60-2C65	Phase 2	[1]
Multiple myeloma	2A83	Discontinued in Phase 3	[1]

• Therapeutic Class: Anticancer Agents
• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 1:
  Molecular Weight (mw); 585.7
  Logarithm of the Partition Coefficient (xlogp); 2.6
  Rotatable Bond Count (rotbonds); 7
  Hydrogen Bond Donor Count (hbonddonor); 4
  Hydrogen Bond Acceptor Count (hbondacc); 9
• Chemical Identifiers:
  Formula: C31H43N3O8
  IUPAC Name: [(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-(prop-2-enylamino)-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate
  Canonical SMILES: C[C@H]1C[C@@H]([C@@H]([C@H](/C=C(/[C@@H]([C@H](/C=C\\C=C(\\C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)/C)OC)OC(=O)N)\\C)C)O)OC
  InChI: InChI=1S/C31H43N3O8/c1-8-12-33-26-21-13-17(2)14-25(41-7)27(36)19(4)15-20(5)29(42-31(32)39)24(40-6)11-9-10-18(3)30(38)34-22(28(21)37)16-23(26)35/h8-11,15-17,19,24-25,27,29,33,36H,1,12-14H2,2-7H3,(H2,32,39)(H,34,38)/b11-9-,18-10+,20-15+/t17-,19+,24+,25+,27-,29+/m1/s1
  InChIKey: AYUNIORJHRXIBJ-TXHRRWQRSA-N
• Cross-matching ID:
  PubChem CID: 6505803
  ChEBI ID: CHEBI:64153
  CAS Number: 75747-14-7
  UNII: 4GY0AVT3L4
  DrugBank ID: DB05134
  TTD ID: D0SC2J
• Repurposed Drugs (RPD): Click to Jump to the Detailed RPD Information of This Drug

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Heat shock protein 90 alpha (HSP90A)	TT78R5H	HS90A_HUMAN	Inhibitor	[2]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
3-hydroxyacyl-CoA dehydrogenase type-2 (HSD17B10)	OT7RJON4	HCD2_HUMAN	Gene/Protein Processing	[3]
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1)	OTTLJH8W	ATS1_HUMAN	Gene/Protein Processing	[4]
Albumin (ALB)	OTVMM513	ALBU_HUMAN	Drug Response	[5]
ALK tyrosine kinase receptor (ALK)	OTV3P4V8	ALK_HUMAN	Gene/Protein Processing	[6]
Alpha-enolase (ENO1)	OTB1KWJS	ENOA_HUMAN	Gene/Protein Processing	[3]
Androgen receptor (AR)	OTUBKAZZ	ANDR_HUMAN	Gene/Protein Processing	[7]
Annexin A1 (ANXA1)	OT5OFDJC	ANXA1_HUMAN	Gene/Protein Processing	[3]
Anterior gradient protein 2 homolog (AGR2)	OTRRZT7W	AGR2_HUMAN	Gene/Protein Processing	[3]
Apoptosis regulator Bcl-2 (BCL2)	OT9DVHC0	BCL2_HUMAN	Gene/Protein Processing	[8]
Apoptotic protease-activating factor 1 (APAF1)	OTJWIVY0	APAF_HUMAN	Gene/Protein Processing	[9]

Molecular Expression Atlas of This Drug

• ICD Disease Classification: 02 Neoplasm
• Disease Class: ICD-11: 2C82 Prostate cancer
• The Studied Tissue: Bone marrow
• The Studied Disease: Multiple myeloma [ICD-11:2C82]

Molecule Name	Molecule Type	Gene Name	p-value	Fold-Change	Z-score
Heat shock protein 90 alpha (HSP90A)	DTT	HSP90AA1	5.98E-06	1.3	4.35

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 45 Cell Line(s) in Bone Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
RPMI-3460/CS1	GDSC1; GDSC2	-2.2491	0.4028	-2.5753	24.2968
HuO9	GDSC1; GDSC2	-3.2998	0.5447	-3.7634	35.2086
ES8	GDSC1; GDSC2	-1.7849	0.7458	-2.1925	20.1271
MHH-ES-1	GDSC1; GDSC2; CTRP2; CCLE	-1.6103	0.4576	-1.6119	44.3389
U2OS	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.2738	1.0615	-1.2794	42.1116
HuO-3N1	GDSC1; GDSC2	-1.0504	4.813	-3.3295	23.4153
NY	GDSC1; GDSC2	-0.4431	4.6083	-2.6831	17.9578
CAL-78	GDSC1; GDSC2; CTRP2; CCLE	-0.3597	4.3906	-0.6884	36.9709
SaOS-2	GDSC1; GDSC2; CTRP2; CCLE	-0.1829	5.3653	-0.7511	36.4781
CHSA0011	GDSC1; GDSC2	-0.1699	5.0461	-2.666	16.9985
TC-71	GDSC1; GDSC2; CCLE	-0.1152	3.2324	-0.466	25.44
SW1353	CTRP2; CCLE	-0.104	6.3673	-0.984	39.1094
CHSA0108	GDSC1; GDSC2	0.1171	2.8118	-1.3095	7.9534
ES7	GDSC1; GDSC2	0.1954	2.9934	-1.3372	7.9107
ES1	GDSC1; GDSC2	0.233	2.4936	-1.0584	6.0533
CAL-72	GDSC1; GDSC2	0.2421	5.3374	-2.4697	14.6635
EW-16	GDSC1; GDSC2	0.2742	4.781	-2.166	12.7977
SK-ES-1	GDSC1; GDSC2; CTRP2; CCLE	0.2772	4.2282	0.0398	32.5363
SJSA-1	GDSC1; GDSC2; CTRP2; CCLE	0.3482	5.436	-0.1927	33.0151
ES6	GDSC1; GDSC2	0.3553	2.5658	-1.0002	5.3714
NOS-1 [Human HNSCC]	GDSC1; GDSC2	0.4279	4.0892	-1.6999	9.5485
EW-12	GDSC2	0.4867	3.313	-1.2705	6.7311
CHSA8926	GDSC1; GDSC2	0.6519	2.3344	-0.6789	2.7312
A-673	GDSC1; GDSC2; CTRP2; CCLE	0.6603	3.5484	0.5699	29.5109
EW-18	GDSC1; GDSC2	0.6788	4.6667	-1.7946	9.4838
ES4	GDSC1; GDSC2	0.7384	5.3804	-2.1023	11.1791
EW-3	GDSC1; GDSC2	0.75	6.6407	-2.7179	14.6575
G-292 clone A141B1	GDSC1; GDSC2; CTRP2	0.822	4.5017	0.5724	28.975
EW-22	GDSC1; GDSC2	0.8569	3.3851	-1.0427	4.4857
EW-1	GDSC1; GDSC2	0.8969	3.7473	-1.1891	5.283
SK-N-MC	CTRP2	0.9584	3.193	0.9224	27.3425
ES5	GDSC1; GDSC2	0.966	5.3871	-1.937	9.6369
Hs 888.T	CTRP2	1.0145	9.9979	-1.265	33.6895
EW-24	GDSC1; GDSC2	1.0199	4.579	-1.5053	6.9235
HOS	GDSC1; GDSC2; CTRP2; CCLE	1.0542	4.3411	0.8597	27.2461
U-CH2	GDSC2	1.0619	5.6383	-1.9906	9.7263
EW-13	GDSC1; GDSC2	1.0682	4.3376	-1.3561	5.9232
EW-7	GDSC1; GDSC2	1.1445	8.0207	-3.1011	15.6582
H-EMC-SS	GDSC1; GDSC2	1.2371	3.3886	-0.8082	2.4463
TC71	CTRP2	1.4471	5.2888	1.0492	25.3494
SK-PN-DW	GDSC1; GDSC2	1.5107	7.183	-2.4237	11.168
CADO-ES1	GDSC1; GDSC2	2.1126	3.7736	-0.5468	0.4503
EW-11	GDSC1; GDSC2	3.1845	5.6567	-0.8126	0.6471
MG-63	GDSC1; GDSC2; CTRP2; CCLE	4.0338	9.7342	1.8119	15.5945
Hs 822.T	CTRP2	6.0463	7.0773	4.6922	0.3494

Cancer Drug Sensitivity Data Curated from 223 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JK1	CTRP2	-1.2811	1.9788	-1.3223	42.2515
MEC1	CTRP2	0.1544	1.9729	0.1499	32.5927
JM1	GDSC1; GDSC2; CTRP2	0.7129	2.4344	0.7067	28.8778
MV4-11	GDSC1; GDSC2; CTRP2	-4.592	-1.9736	-4.5927	64.1146
KMS-21-BM	CTRP2	-4.5263	-3.5023	-4.5263	63.7615
BONNA-12	GDSC2	-4.3298	-1.5906	-4.4049	43.6969
KMS-11	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-4.2409	-1.8637	-4.2413	61.8254
SR	GDSC1; GDSC2; CTRP2	-3.6318	-1.7	-3.6318	57.7977
OCI-AML-2	GDSC1; GDSC2; CTRP2; CCLE	-3.3474	-2.1333	-3.3474	55.9071
MOLM-13	GDSC1; GDSC2; CTRP2	-2.7973	-1.4943	-2.7973	52.2423
NKM-1	GDSC1; GDSC2	-2.7178	-0.1194	-2.9342	28.3829
NB4	GDSC1; GDSC2; CTRP2	-2.6292	-1.3588	-2.6293	51.1229
Kasumi-2	CTRP2; CCLE	-2.6281	4.1238	-3.0966	50.937
L-363	GDSC1; GDSC2; CTRP2; CCLE	-2.6004	0.0697	-2.6049	50.9271
JURL-MK1	GDSC1; GDSC2; CTRP2	-2.5912	-0.5572	-2.5917	50.8689
BC-3	GDSC2	-2.5731	-0.9691	-2.6149	26.0336
TUR	GDSC1; GDSC2	-2.5004	-0.0754	-2.7085	26.1725
AML-193	CTRP2	-2.4275	-0.695	-2.4276	49.7787
SKM-1	GDSC1; GDSC2; CTRP2; CTRP1	-2.2954	-0.8161	-2.2954	48.8986
DEL	GDSC1; GDSC2; CTRP2; CCLE	-2.2463	-0.696	-2.2463	48.5717
U-937	CTRP2; CTRP1; CCLE	-2.1245	-0.0044	-2.1256	47.762
KMS-26	CCLE	-2.1136	-0.7864	-2.1138	43.9175
KOPN-8	GDSC1; GDSC2	-2.111	0.0999	-2.3318	22.3488
AMO1	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-2.0986	-0.3498	-2.0988	47.5878
H9	GDSC1; GDSC2	-2.0499	0.1601	-2.2828	21.8035
SEM	CTRP2	-2.0458	0.8872	-2.0589	47.2562
SUP-M2	GDSC1; GDSC2; CTRP2; CCLE	-2.042	-0.5408	-2.042	47.2105
Ku812	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-2.0134	0.6381	-2.0195	47.6055
L-1236	GDSC1; GDSC2; CTRP2	-2.0016	6.5128	-3.091	47.7136
MOLM-16	GDSC1; GDSC2; CTRP2; CTRP1	-1.8732	-0.203	-1.8734	46.0868
BDCM	CTRP2; CCLE	-1.8626	0.4681	-1.8658	46.0226
JVM-3	GDSC1; GDSC2; CTRP2; CCLE	-1.8153	1.2073	-1.834	45.7406
HuT 78	CTRP2; CCLE	-1.799	0.3723	-1.8009	45.5962
SU-DHL-1	GDSC2; CTRP2	-1.7295	-0.8838	-1.7295	45.1286
Hs 445	GDSC2	-1.7113	0.1179	-1.9011	18.1791
KE-97	CTRP2; CTRP1; CCLE	-1.7006	0.9044	-1.7075	45.5506
ML-2	GDSC1; GDSC2	-1.6939	5.1885	-4.1127	29.2565
SCC-3	GDSC2	-1.6111	0.0267	-1.7656	16.9823
THP-1	GDSC1; GDSC2; CTRP2; CTRP1	-1.6061	0.1511	-1.6065	44.3078
JSC-1	GDSC1; GDSC2	-1.588	0.9987	-2.0802	18.6517
OCI-AML-3	GDSC1; GDSC2; CTRP2; CTRP1	-1.5113	0.774	-1.5151	43.6855
MJ	CTRP2; CCLE	-1.4888	0.7088	-1.4917	43.5335
NCI-H929	GDSC1; GDSC2; CTRP2	-1.4392	0.3494	-1.4397	43.1961
Karpas-299	GDSC1; GDSC2; CTRP2; CCLE	-1.4016	1.8303	-1.4379	43.037
SU-DHL-16	GDSC1; GDSC2	-1.3713	-0.1963	-1.4479	14.1595
BC-1	GDSC1; GDSC2	-1.3094	0.9337	-1.7599	15.6456
CMK-86	CCLE	-1.1448	1.2508	-1.1925	35.7938
KMS-12-BM	GDSC2; CTRP2; CCLE	-1.1117	0.846	-1.1135	41.0188
HD-MY-Z	CTRP2; CCLE	-1.0539	4.4948	-1.4693	41.5818
EoL-1	GDSC1; GDSC2; CTRP2	-1.0205	0.8858	-1.0221	40.4102
KMS-27	CTRP2	-1.0051	1.3233	-1.0121	40.3242
K-562	GDSC1; GDSC2; CTRP2	-1.0035	1.8844	-1.0296	40.3696
Mono-Mac-1	CTRP2; CCLE	-0.9992	8.162	-2.6038	43.0605
NCO2	CTRP2; CCLE	-0.9894	0.9158	-0.9911	40.2035
ATN-1	GDSC1; GDSC2	-0.9893	1.3361	-1.6028	13.4437
CRO-AP2	GDSC1; GDSC2	-0.9682	1.0248	-1.443	12.4061
YT	GDSC1; GDSC2	-0.949	1.346	-1.5665	13.0709
Mino	CTRP2; CCLE	-0.8943	1.8598	-0.9161	39.6315
Karpas-422	GDSC1; GDSC2; CTRP2; CCLE	-0.8921	2.6345	-0.9697	39.7741
KY821	GDSC1; GDSC2	-0.8869	1.9459	-1.784	14.1576
SUP-HD1	GDSC1; GDSC2; CTRP2	-0.8729	2.3692	-0.9254	39.5775
SU-DHL-5	GDSC1; GDSC2; CTRP1	-0.7997	0.0318	-0.8494	10.1384
LAMA-84	GDSC1; GDSC2; CTRP2	-0.7777	0.8754	-0.7783	38.7897
KCL-22	GDSC1; GDSC2; CTRP2; CCLE	-0.743	1.3758	-0.7477	38.5717
PL21	CTRP2; CTRP1	-0.7386	2.6384	-0.8083	38.7367
RPMI-6666	GDSC1; GDSC2; CTRP2	-0.6996	2.3139	-0.7406	38.3945
RPMI-8226	GDSC1; GDSC2; CTRP2; CTRP1	-0.577	2.8911	-0.6642	37.7178
NK-92MI	GDSC2	-0.5636	0.3812	-0.749	6.6854
BL-70	CTRP2; CTRP1; CCLE	-0.5598	0.975	-0.5601	38.0186
VL51	GDSC1; GDSC2	-0.5592	1.4548	-1.2334	9.6023
SU-DHL-10	GDSC1; GDSC2; CTRP2; CCLE	-0.5495	1.4022	-0.5528	37.2784
PL-21	GDSC1; GDSC2	-0.5438	3.661	-2.3013	16.0937
EM-2	GDSC1; GDSC2; CTRP2; CCLE	-0.5241	0.9374	-0.5244	37.099
OCI-Ly10	CTRP2; CTRP1; CCLE	-0.516	4.888	-0.9818	38.3213
WIL2 NS	GDSC1; GDSC2	-0.4847	0.4397	-0.6907	6.023
MEC-1	CCLE	-0.4833	3.5151	-0.9536	31.8895
RPMI-8866	GDSC1; GDSC2	-0.4697	0.5652	-0.73	6.1978
Karpas-45	GDSC1; GDSC2	-0.4658	1.33	-1.0842	8.3504
A3/Kawakami	GDSC1; GDSC2; CTRP2	-0.4603	0.8387	-0.4605	36.6737
GA-10	GDSC1; GDSC2; CTRP2	-0.4598	1.5192	-0.4637	36.6826
CTV-1	GDSC1; GDSC2	-0.4586	2.4305	-1.6158	11.6375
OPM-2	GDSC1; GDSC2; CTRP2; CCLE	-0.3992	2.0152	-0.4146	36.3166
HC-1	GDSC1; GDSC2	-0.3937	1.5764	-1.1363	8.4274
WSU-DLCL2	GDSC1; GDSC2; CTRP2; CTRP1	-0.3923	0.5962	-0.3923	36.2199
U-698-M	GDSC1; GDSC2	-0.3922	1.5011	-1.098	8.1829
BV-173	GDSC1; GDSC2; CTRP2	-0.3694	4.3577	-0.6915	37.0159
OCI-AML-5	GDSC1; GDSC2; CTRP2; CCLE	-0.3309	1.176	-0.3315	35.813
CESS	GDSC1; GDSC2	-0.3057	1.4217	-0.9793	7.1502
OCI-Ly7	GDSC1; GDSC2	-0.2807	0.7292	-0.6186	4.8168
KMS-20	CTRP2	-0.2799	2.988	-0.3606	35.729
Farage	GDSC1; GDSC2	-0.2661	2.1476	-1.3029	9.0557
DoHH2	GDSC1; GDSC2; CTRP2; CCLE	-0.2462	1.8206	-0.253	35.2708
QIMR-WIL	GDSC1; GDSC2	-0.2176	2.2686	-1.3203	9.0124
JJN-3	GDSC1; GDSC2; CTRP2	-0.217	1.4368	-0.2184	35.0569
L-540	GDSC1; GDSC2; CTRP2	-0.1497	3.0927	-0.2346	34.8778
SU-DHL-8	GDSC1; GDSC2; CTRP2; CCLE	-0.1043	4.3212	-0.3949	35.2045
ALL-PO	GDSC1; GDSC2	-0.0699	3.3796	-1.7484	11.2458
SIG-M5	GDSC2; CTRP2; CCLE	-0.0649	1.1853	-0.065	34.0393
F-36P	CTRP2; CCLE	-0.0435	4.2634	-0.3161	34.7536
KM-H2	GDSC1; GDSC2; CTRP2	-0.0385	2.5024	-0.0667	33.9559
SUP-T1	GDSC1; GDSC2; CTRP2; CCLE	-0.0374	3.1582	-0.1232	34.1354
IM-9	GDSC1; GDSC2	-0.026	1.9372	-0.9903	6.346
HT	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-0.0207	3.0051	-0.0811	34.6598
KHM-1B	CTRP2; CCLE	-0.0196	4.0345	-0.2427	36.8626
HDLM-2	GDSC1; GDSC2; CTRP2	-0.0021	4.6201	-0.3532	34.7162
GR-ST	GDSC1; GDSC2	0.0344	2.6164	-1.2796	8.0003
ARH-77	GDSC1; GDSC2	0.0533	3.5987	-1.7551	10.9258
DG-75	GDSC1; GDSC2	0.1055	3.6059	-1.7158	10.5317
JM-1	CCLE	0.1261	1.6308	0.1058	24.7695
CTB-1	GDSC1; GDSC2	0.1395	3.0213	-1.396	8.4355
Jiyoye	GDSC1; GDSC2	0.1514	2.5139	-1.1331	6.745
MC116	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	0.1598	1.051	0.1598	33.2753
MM1.S	GDSC1; GDSC2; CTRP2	0.1754	1.5556	0.1749	32.4395
NOMO-1	GDSC1; GDSC2; CTRP2; CTRP1	0.1825	3.326	0.0899	32.6961
MHH-CALL-2	GDSC1	0.1833	3.2454	-1.4726	10.9181
Kasumi-1	GDSC2; CTRP2	0.2056	2.1385	0.1984	32.2608
Loucy	GDSC1; GDSC2	0.2345	2.1532	-0.888	4.9763
MY-M12	GDSC1; GDSC2	0.2493	1.7259	-0.665	3.5392
MOLP-8	GDSC1; GDSC2; CTRP2; CCLE	0.2574	2.3172	0.2461	31.9296
TK [Human B-cell lymphoma]	GDSC1; GDSC2	0.2606	1.9372	-0.7609	4.1111
NU-DUL-1	GDSC1; GDSC2; CTRP2; CTRP1	0.279	1.1698	0.279	31.7475
KMOE-2	GDSC1; GDSC2	0.2827	3.0351	-1.2889	7.3711
U266B1	GDSC1; GDSC2; CTRP2	0.283	1.9263	0.2804	31.7299
Ri-1	CTRP2	0.2903	2.952	0.2433	31.8289
697	GDSC1; GDSC2; CTRP2; CCLE	0.3101	2.1213	0.3048	31.5584
EHEB	GDSC1; CTRP2	0.3111	3.3323	0.2258	34.0825
MHH-CALL-4	GDSC2; CTRP2	0.3455	3.6855	0.2132	31.7434
HH [Human lymphoma]	GDSC1; GDSC2; CTRP2; CCLE	0.359	3.3934	0.2691	31.514
CML-T1	GDSC1; GDSC2; CTRP2	0.3632	2.2693	0.3554	31.2129
MOLT-16	GDSC1; GDSC2; CTRP2; CCLE	0.3898	2.5347	0.3733	31.0645
BL-41	GDSC1; GDSC2; CCLE	0.4125	1.6472	0.4014	20.0004
KE-37	GDSC1; GDSC2; CTRP2	0.4505	3.6814	0.3265	31.0187
EJM	GDSC1; GDSC2; CTRP2; CTRP1	0.463	2.7095	0.4401	30.5982
PF-382	GDSC1; GDSC2; CTRP2	0.4815	3.0318	0.4368	30.548
SUP-B8	GDSC1; GDSC2	0.5051	2.4776	-0.8473	4.0621
A4/Fukuda	GDSC1; GDSC2; CTRP2	0.5159	1.2777	0.5159	30.1692
HL-60	GDSC1; GDSC2; CTRP2	0.5321	3.6389	0.4204	30.4354
NU-DHL-1	CTRP2	0.5402	3.5524	0.4413	30.3386
MOLM-6	CTRP2	0.5476	2.6724	0.5293	30.0194
Karpas-1106P	GDSC1; GDSC2	0.5608	2.0022	-0.5813	2.3335
P32/ISH	GDSC1; GDSC2	0.5634	1.936	-0.5484	2.1355
Karpas-231	GDSC1; GDSC2	0.5645	2.8343	-0.9787	4.7348
Peer	CTRP2	0.5707	2.0162	0.5692	29.8094
MEG-01	GDSC1; GDSC2; CCLE	0.5771	2.3448	0.5015	18.9863
OCI-Ly3	CTRP2	0.5853	1.9699	0.5843	29.7106
CCRF-CEM	GDSC1; GDSC2	0.6323	2.6607	-0.8474	3.7816
Pfeiffer	CTRP2; CCLE	0.6465	1.7126	0.6464	29.2998
P31/FUJ	GDSC1; GDSC2; CTRP2; CCLE	0.6656	2.7958	0.6446	29.2423
MLMA	GDSC1; GDSC2	0.6693	3.5981	-1.2763	6.3258
M-07e	CTRP2	0.7201	3.4489	0.6459	29.0584
Hs 611.T	CTRP2	0.7376	2.1828	0.7357	28.699
NALM-6	GDSC1; GDSC2; CTRP2	0.7405	3.1258	0.7	28.809
Namalwa	GDSC1; GDSC2; CTRP2	0.7474	2.5182	0.7397	28.653
SET-2	CTRP2	0.7598	1.5872	0.7598	28.5449
BALL-1	GDSC1; GDSC2	0.7803	6.0429	-2.3984	12.7932
MOLT-3	CTRP2	0.8003	1.6778	0.8003	28.2746
WSU-NHL	GDSC1	0.8063	3.9102	-1.3307	7.8753
RL	GDSC1; GDSC2; CTRP2	0.8276	2.4234	0.8233	28.1074
KMS-34	CTRP2; CCLE	0.8447	3.5642	0.7642	28.25
KG-1	GDSC1; GDSC2; CCLE	0.8534	1.9728	0.8385	16.6146
MOLT-4	GDSC1; GDSC2	0.8574	4.2239	-1.4471	6.9363
DND-41	GDSC1; GDSC2; CTRP2	0.8605	2.3588	0.8576	27.8835
EB1	CTRP2; CCLE	0.8676	4.4838	0.6261	28.6451
Granta-519	GDSC1; GDSC2; CTRP2; CCLE	0.8826	4.0454	0.7311	28.2394
ALL-SIL	GDSC1; GDSC2; CTRP2; CCLE	0.9245	2.6768	0.9155	27.4775
Jurkat	GDSC1; GDSC2; CTRP2; CCLE	0.9514	3.1435	0.919	27.3769
LP-1	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	0.9724	4.7082	0.6876	28.0982
CMK	GDSC1; CTRP2	0.9878	3.7079	0.8977	27.33
Daudi	GDSC1; GDSC2; CTRP2	1.0137	2.3843	1.0118	26.8595
JVM-2	GDSC1; GDSC2; CTRP2	1.0182	5.1977	0.6077	28.2246
SU-DHL-4	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.0861	3.0663	1.064	26.4449
OCI-Ly19	GDSC1; GDSC2; CTRP2	1.091	2.841	1.08	26.3749
BE-13	GDSC1; GDSC2	1.1138	2.7977	-0.6159	1.6158
OCI-M1	GDSC1; GDSC2; CTRP2	1.127	2.738	1.12	26.1215
MOLT-13	GDSC1; GDSC2; CTRP2	1.145	2.9193	1.1322	26.0214
MHH-PREB-1	GDSC1; GDSC2	1.1454	2.6224	-0.5245	1.1277
P12-Ichikawa	GDSC1; CTRP2; CCLE	1.2074	3.2281	1.1795	25.6562
TF-1	CTRP2	1.2252	3.1866	1.2007	25.5262
EB2	GDSC1; GDSC2; CCLE	1.2265	3.8166	0.7932	15.5021
Ci-1	CTRP2; CCLE	1.2277	6.425	0.4346	28.1515
KYO-1	CTRP2	1.2644	2.2216	1.2642	25.1837
P30/OHK	GDSC1; GDSC2	1.2805	3.9935	-1.0573	3.7584
KMS-28BM	CTRP2	1.3298	3.7717	1.2539	25.0042
CA46	GDSC1; GDSC2; CTRP2	1.3398	3.1153	1.3234	24.7355
MOLP-2	CTRP2	1.3462	3.8671	1.2583	24.9358
Ramos.2G6.4C10	GDSC1; GDSC2	1.3731	3.1023	-0.6114	1.2714
SU-DHL-6	GDSC1; GDSC2; CTRP2; CCLE	1.3941	2.7591	1.3907	24.3301
RCH-ACV	GDSC1; GDSC2; CTRP2	1.3942	4.1713	1.2607	24.7736
MN-60	GDSC1; GDSC2	1.4106	3.5152	-0.7679	1.9845
GDM-1	GDSC1; GDSC2; CTRP2; CTRP1	1.4307	5.1367	1.0751	25.3086
P3HR-1	CTRP2; CTRP1; CCLE	1.4364	4.0763	1.3366	25.1982
RPMI-8402	GDSC1; GDSC2; CTRP2; CCLE	1.4844	3.748	1.4213	23.9303
LC4-1	GDSC1; GDSC2	1.496	4.4356	-1.1298	3.7943
RS4;11	GDSC1; GDSC2; CTRP2	1.5002	4.1671	1.3759	24.0357
DB	GDSC1; GDSC2; CTRP2	1.5384	6.5797	0.7115	26.2574
Reh	GDSC1; GDSC2; CTRP2; CCLE	1.5839	4.671	1.3629	23.8168
SUP-B15	GDSC1; GDSC2; CTRP2	1.6474	4.5147	1.4671	23.2514
L-428	GDSC1; GDSC2; CTRP2; CCLE	1.6713	4.5556	1.4843	23.116
ME1	GDSC1; GDSC2	1.6727	3.2161	-0.5186	0.6231
Sc-1	GDSC1	1.7063	3.3413	-0.5524	0.8946
JeKo-1	GDSC1; GDSC2; CTRP2	1.7199	6.4758	0.9449	24.8944
KMS-18	CTRP2	1.7449	3.6921	1.7031	22.1224
ST486	GDSC1; CTRP2	1.7597	7.6713	0.512	26.2888
ROS-50	GDSC1; GDSC2	1.7889	3.6393	-0.6326	0.9542
VAL	GDSC1; GDSC2	1.7978	3.9726	-0.7634	1.4965
HEL 92.1.7	CTRP2; CCLE	1.8122	4.0998	1.7228	21.8375
HEL	GDSC1; GDSC2; CTRP2	1.9543	4.8878	1.7135	21.4236
KO52	CTRP2; CCLE	1.9638	4.1378	1.8795	20.8099
TALL-1 [Human adult T-ALL]	GDSC2; CTRP2	2.1416	6.6053	1.3463	22.211
SK-MM-2	GDSC1; GDSC2; CTRP2; CCLE	2.2326	5.6271	1.7989	20.2744
RC-K8	GDSC1	2.2513	3.6672	-0.4564	0.2411
MOTN-1	CTRP2	2.685	5.4955	2.3336	16.9687
HPB-ALL	CTRP2	3.3144	5.421	3.0416	12.4988
HAL-01	GDSC1; GDSC2	3.3227	9.7645	-2.4698	7.8971
SUP-T11	CTRP2	3.3923	5.7754	2.9998	12.4315
Raji	GDSC1; GDSC2; CTRP2; CCLE	3.6198	6.3726	2.9989	11.8129
MHH-CALL-3	CTRP2	3.8844	16.8751	-1.8635	27.7421
Mono-Mac-6	GDSC1; GDSC2; CTRP2	3.9467	15.0411	-0.8958	25.098
ME1	CTRP2	5.055	10.0755	2.5377	10.4948
Toledo	CTRP2; CCLE	6.6025	8.8519	4.2288	1.3466
Karpas-620	GDSC1; GDSC2; CTRP2; CCLE	7.1095	8.464	4.6064	0.1416
REC-1	CTRP2	7.3655	8.9996	4.5127	0.2139
KMM-1	CTRP2; CCLE	8.4871	10.7971	4.296	0.2786

Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Oesophagus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
TE15	CTRP2	-0.2114	5.5092	-0.8248	36.7736
TE8	CTRP2	0.763	5.8263	0.1373	30.6033
OE19	GDSC1; GDSC2; CTRP2	-4.1496	5.7074	-5.1779	57.6475
T.T	GDSC1; GDSC2	-3.2237	0.0103	-3.521	33.7664
KYSE-180	GDSC1; GDSC2; CTRP2; CCLE	-3.0675	-1.0494	-3.0678	54.0403
TE-15	GDSC1; GDSC2; CCLE	-3.0599	0.5147	-3.1365	46.8607
TE-1	GDSC1; GDSC2; CTRP2; CCLE	-2.6231	0.9508	-2.652	51.0606
TE-8	GDSC1; GDSC2	-2.5691	-0.0905	-2.7795	26.8699
TE-11	GDSC1; GDSC2; CTRP2; CCLE	-2.3538	2.578	-2.5141	49.3363
TE-4	GDSC1; GDSC2; CTRP2	-2.2666	2.3066	-2.3872	48.7756
OE21	GDSC1; GDSC2; CTRP2; CCLE	-2.0003	3.7705	-2.337	47.267
KYSE-270	GDSC1; GDSC2	-1.8072	-0.1972	-1.9221	18.7348
KYSE-510	GDSC1; GDSC2; CTRP2; CCLE	-1.7474	1.2122	-1.7647	45.2859
KYSE-520	GDSC1; GDSC2; CTRP2; CCLE	-1.6208	3.5353	-1.8801	44.8522
TE-6	GDSC1; GDSC2; CTRP2	-1.5897	4.0244	-1.9448	44.7914
KYSE-410	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.4974	4.0753	-1.8343	44.7603
TE-9	GDSC1; GDSC2; CTRP2; CCLE	-1.469	1.571	-1.4938	43.4565
KYSE-150	GDSC1; GDSC2; CTRP2; CCLE	-1.2406	4.3662	-1.642	42.7135
TE-14	CTRP2	-1.1203	3.4308	-1.3214	41.5648
KYSE-70	GDSC1; GDSC2; CTRP2; CCLE	-0.4379	4.4021	-0.7763	37.5015
TE-5	GDSC1; GDSC2; CTRP2; CCLE	-0.0741	3.1835	-0.1652	34.3957
OE33	GDSC1; GDSC2; CTRP2; CCLE	-0.0625	6.4533	-0.9686	36.5824
TE-10	GDSC1; GDSC2; CTRP2	0.7735	6.3977	-0.0455	31.1439
KYSE-450	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.2094	4.459	1.0237	26.9851
KYSE-30	CTRP2; CCLE	1.295	3.8747	1.2024	25.2931
EC-GI-10	GDSC1; GDSC2; CTRP2	1.6596	6.8959	0.72	25.8659
KYSE-140	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.771	5.2697	1.4404	23.7973
COLO 680N	GDSC1; GDSC2; CTRP2	5.1981	18.1535	-1.3825	23.8274

Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Pancreas Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
N2a-PK1	CTRP2	-1.4135	2.7539	-1.5355	43.2979
MIA PaCa-2	GDSC1; GDSC2; CTRP2; CCLE	-4.8312	0.976	-4.9543	63.8493
KP-4	GDSC1; GDSC2; CTRP2; CCLE	-4.0563	-1.9663	-4.0564	60.6176
PL45	CCLE	-3.7354	2.2037	-4.1494	56.1918
PK-1	CCLE	-3.5252	1.0525	-3.6995	55.3326
SW1990	GDSC1; GDSC2; CTRP2; CCLE	-3.006	-1.0349	-3.0063	53.6314
BxPC-3	GDSC1; GDSC2; CTRP2; CCLE	-2.7935	-1.3538	-2.7935	52.2173
Panc 03.27	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-2.4461	0.4003	-2.4531	50.4452
Capan-2	GDSC1; CTRP2; CTRP1; CCLE	-2.2274	2.2672	-2.3325	49.054
Panc 05.04	CTRP2	-2.0857	5.2326	-2.7891	47.9774
KCI-MOH1	CCLE	-1.9938	2.1145	-2.2362	43.5106
PaTu 8988s	CTRP2	-1.7177	5.0282	-2.3308	45.8464
PSN1	GDSC1; GDSC2; CTRP2; CCLE	-1.6413	0.0729	-1.6416	44.542
Panc 02.03	GDSC1; GDSC2; CTRP2; CCLE	-1.3801	3.5962	-1.6312	43.3236
HuP-T4	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.3264	3.5899	-1.5554	43.5358
DAN-G	GDSC1; GDSC2; CTRP2	-1.2513	3.5551	-1.4845	42.4715
Hs 766T	GDSC1; GDSC2; CTRP2; CCLE	-1.2286	4.119	-1.5728	42.5373
PaTu 8988t	GDSC1; GDSC2; CTRP2	-1.0044	3.4817	-1.2053	40.8159
PK-45H	CTRP2; CCLE	-0.746	3.7461	-0.9736	39.2069
Panc 10.05	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-0.639	5.5157	-1.2593	40.0468
HPAC	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-0.6388	7.6325	-1.9667	41.2977
Panc 04.03	GDSC1; GDSC2; CTRP2; CCLE	-0.5827	4.6103	-0.9838	38.5869
KP-2	GDSC1; GDSC2; CTRP2; CCLE	-0.5734	4.9737	-1.0673	38.7495
PL4	GDSC1; GDSC2	-0.5062	1.7877	-1.3443	10.1059
Panc 08.13	GDSC1; GDSC2; CTRP2	-0.4906	4.4956	-0.8556	37.9091
KP-3	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-0.3097	5.5144	-0.8997	37.9699
TCC-Pan2	CTRP2	-0.0427	5.1483	-0.536	35.3856
AsPC-1	GDSC1; GDSC2; CTRP2; CCLE	0.0306	5.641	-0.6011	35.3009
PK-59	CTRP2; CCLE	0.0377	3.443	-0.0802	33.7392
YAPC	GDSC1; GDSC2; CTRP2	0.4246	4.7439	0.0814	31.9047
QGP-1	GDSC1; GDSC2; CTRP1; CCLE	0.5175	8.2179	-0.9598	35.165
KP-1N	GDSC1; GDSC2; CCLE	0.5505	3.4666	0.1863	20.39
KP-1NL	CCLE	0.7547	5.2886	-0.308	24.2424
SU.86.86	GDSC1; GDSC2; CTRP2; CCLE	0.9324	6.686	0.0216	30.4214
HuP-T3	GDSC1; GDSC2; CTRP2; CCLE	1.3924	6.1063	0.7255	26.652
MZ-PC-1	GDSC1; GDSC2	1.5247	4.0441	-0.9372	2.7002
SUIT-2	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.5793	4.9954	1.3041	24.8621
HPAF-II	GDSC1; CTRP2; CCLE	1.606	18.2182	-4.5893	39.1468
PaTu 8902	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	2.1718	6.4579	1.4858	22.4496
CFPAC-1	GDSC1; GDSC2; CTRP2; CTRP1	2.2299	9.5099	0.2572	26.5442
SNU-213	CTRP2	2.2609	7.7466	1.0017	23.1382
Capan-1	GDSC1; GDSC2; CTRP2	3.0457	13.6107	-1.0004	27.4775
L3.3	CTRP2; CCLE	4.7378	15.0116	-0.1969	21.316
SNU-410	CTRP2	5.4278	13.6501	1.0568	15.6317

Cancer Drug Sensitivity Data Curated from 79 Cell Line(s) in Skin Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SH4	CTRP2	0.0449	7.1736	-1.1118	36.536
IST-MEL1	GDSC1; GDSC2	-8.0665	2.0479	-9.4368	64.8649
WT2-iPS	GDSC1; GDSC2; CTRP2; CCLE	-5.8936	-5.276	-5.8936	72.8708
RPMI-7951	GDSC1; GDSC2; CTRP2; CCLE	-5.6653	-3.6615	-5.6653	71.2956
WM266-4	CTRP2; CCLE	-5.5237	-3.0901	-5.5239	70.2744
WM115	GDSC1; GDSC2; CTRP2; CCLE	-4.6646	-1.6367	-4.667	64.4966
WM278	GDSC1; GDSC2	-4.3373	-2.4112	-4.3497	43.5736
Hs 938.T	GDSC1; GDSC2; CCLE	-4.2578	0.397	-4.3913	55.4338
CP50-MEL-B	GDSC1; GDSC2	-4.2567	-1.7255	-4.3126	42.9189
WM793	GDSC1; GDSC2; CTRP2; CCLE	-4.0834	-1.4072	-4.0848	60.7509
MZ-MEL-2	GDSC1; GDSC2	-3.8609	-1.4467	-3.9245	39.0254
G-mel	GDSC1; GDSC2	-3.3484	0.838	-3.9131	36.0596
M14	GDSC1	-3.298	1.2531	-4.0051	43.4746
451Lu	GDSC1; GDSC2	-3.0577	0.7002	-3.5514	33.0396
LOX-IMVI	GDSC1; GDSC2; CTRP2; CCLE	-2.9931	-1.5591	-2.9931	53.547
A-431	GDSC1; GDSC2	-2.8977	-0.2057	-3.1087	30.1446
SF8657	CCLE	-2.7709	1.1769	-2.9101	49.595
COLO 679	GDSC1; GDSC2; CCLE	-2.733	1.349	-2.8954	44.57
COLO 792	GDSC1; GDSC2; CTRP2	-2.7202	0.3098	-2.73	51.7138
Hs 852.T	CTRP2; CTRP1; CCLE	-2.7072	3.0043	-2.9434	51.9456
Hs 695T	CCLE	-2.6982	1.4188	-2.8692	49.0281
SK-MEL-24	GDSC1; GDSC2; CTRP2; CCLE	-2.6797	-0.9279	-2.6798	51.4587
Malme-3M	CCLE	-2.5422	2.5689	-2.9363	47.962
GAK	GDSC1; GDSC2	-2.4172	1.9968	-3.3619	29.084
HMV-II	GDSC1; GDSC2	-2.3957	2.5343	-3.5699	29.9359
MMAc-SF	GDSC1; GDSC2	-2.3067	4.2225	-4.2455	32.2517
SH-4	GDSC1; GDSC2	-2.2783	2.0055	-3.2207	27.7817
MZ-MEL-7	GDSC1; GDSC2	-2.1563	2.4606	-3.2918	27.5899
LB2518-MEL	GDSC1; GDSC2	-1.9812	1.7212	-2.7911	24.2817
A-375	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.68	1.1826	-1.6948	44.8333
WM1552C	GDSC1; GDSC2	-1.4893	1.9315	-2.3769	19.9575
A-388	GDSC1; GDSC2	-1.408	2.9645	-2.7732	21.8625
Mel JuSo	GDSC1; GDSC2; CTRP2	-1.39	2.5837	-1.4903	43.1011
CHL-1	GDSC1; GDSC2; CCLE	-1.3697	2.141	-1.5647	34.4218
WM35	GDSC1; GDSC2	-1.224	0.4685	-1.4877	13.7184
WM88	CTRP2; CCLE	-1.0024	4.732	-1.4721	41.3678
DJM-1	GDSC1; GDSC2	-0.8316	2.2337	-1.8679	14.4693
HT-144	GDSC1; GDSC2; CTRP2; CCLE	-0.7455	4.7568	-1.1981	39.7339
RVH-421	GDSC1; GDSC2; CTRP2; CCLE	-0.6867	3.9291	-0.9447	38.8992
IPC-298	GDSC1; GDSC2; CTRP2; CCLE	-0.4071	6.6718	-1.4173	38.8692
HMCB	CTRP2; CCLE	-0.2831	5.8182	-0.998	37.4694
COLO 829	GDSC1; GDSC2; CTRP2	-0.2186	8.2069	-1.7911	38.8985
VMRC-MELG	GDSC2	-0.0685	1.5483	-0.832	5.4705
A2058	GDSC1; GDSC2; CTRP2; CCLE	0.0146	5.8349	-0.6793	35.5684
COLO 783	GDSC1; GDSC2	0.5709	2.9875	-1.0488	5.1525
Hs 294T	CTRP2; CCLE	0.6265	4.7675	0.2957	30.5375
CP66-MEL	GDSC1; GDSC2	0.7231	5.2353	-2.0421	10.8607
UACC-62	GDSC1; GDSC2; CTRP2; CCLE	1.3164	8.4529	-0.2797	30.1392
LB373-MEL-D	GDSC1; GDSC2	1.3596	5.32	-1.63	6.9388
SK-MEL-1	GDSC1; GDSC2; CTRP2; CTRP1	1.5674	9.0263	-0.27	29.3587
CJM [Human melanoma]	CTRP2	1.625	5.7016	1.1146	24.5735
Hs 895.T	CTRP2; CCLE	1.6827	4.9642	1.3973	23.3879
K029AX	CTRP2; CCLE	1.8096	8.8749	0.0445	27.6842
IGR-1	GDSC1; GDSC2; CTRP2	1.8289	5.7071	1.3342	23.1706
UACC-257	GDSC1; GDSC2; CTRP2; CCLE	1.9775	9.1428	0.0954	27.043
Hs 936.T	CTRP2; CTRP1; CCLE	2.1796	8.8007	0.5248	25.8077
Hs 944.T	CTRP2; CTRP1; CCLE	2.2522	9.97	0.069	27.0774
COLO 800	GDSC1; GDSC2; CTRP2	2.2678	14.5883	-2.2013	32.2818
WM983B	CTRP2; CCLE	2.6653	11.2441	-0.2081	26.1398
Mel Ho	GDSC1; GDSC2; CTRP2; CCLE	3.0134	11.6203	-0.0587	24.7885
MeWo	GDSC1; GDSC2; CTRP2; CCLE	3.1522	10.856	0.4426	22.7866
WM1799	CTRP2; CCLE	3.4186	16.2755	-1.9776	29.0418
SK-MEL-2	GDSC1; GDSC2; CTRP2; CCLE	3.4313	11.4668	0.4064	22.2324
SK-MEL-30	GDSC1; GDSC2; CTRP2; CCLE	3.535	11.4296	0.5206	21.5918
Hs 688(A).T	CTRP2	3.7659	12.0233	0.4395	21.3337
IGR-37	GDSC1; GDSC2; CTRP2; CCLE	4.4489	17.4474	-1.6601	26.0477
SK-MEL-3	GDSC1; GDSC2; CTRP2	4.7456	16.164	-0.7663	23.0239
Hs 940.T	GDSC1; GDSC2; CTRP2	4.7526	5.8488	4.3791	3.4157
MDA-MB-435S	CTRP2; CCLE	4.8988	13.0448	0.9222	17.1658
Hs 934.T	CTRP2	4.9204	11.4352	1.7451	13.9791
G-361	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	6.1475	16.8437	0.1544	18.143
IGR-39	CTRP2; CCLE	6.1675	19.3687	-1.2046	21.537
SK-MEL-28	GDSC1; GDSC2; CTRP2; CTRP1	6.2546	7.1981	4.7341	0.1659
SK-MEL-31	GDSC1; GDSC2; CTRP2; CCLE	6.306	15.8102	0.6733	15.4155
A101D	GDSC1; GDSC2; CTRP2	6.3298	14.8411	1.1717	13.5783
Hs 839.T	CTRP2	6.6355	13.5029	2.0567	9.6977
SK-MEL-5	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	6.8515	8.8724	4.3446	0.8038
COLO 741	CTRP2; CTRP1; CCLE	7.608	24.6938	-2.6131	23.1361
EquiPSC Line K2	GDSC1; GDSC2	-0.9649	3.5096	-2.612	19.3301

Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
ESO-26	GDSC1; GDSC2	-5.4221	-2.9418	-5.4404	54.3029
KYAE-1	GDSC1; GDSC2	-4.2703	-2.1895	-4.291	42.9341
FLO-1	GDSC1; GDSC2	-3.1961	1.2392	-3.8905	35.1593
SK-GT-4	GDSC1; GDSC2	-2.4974	2.9794	-3.8699	31.6647
TE-12	GDSC1; GDSC2	-1.8456	1.8708	-2.7146	23.2962
HCE-4	GDSC1; GDSC2	-1.5757	1.7931	-2.4033	20.4542
ESO-51	GDSC1; GDSC2	-1.3683	1.6511	-2.1286	18.04
OACP4 C	GDSC1; GDSC2	-0.367	4.1119	-2.3693	15.9196
KYSE-220	GDSC1; GDSC2	0.1447	2.6988	-1.2308	7.38
OACM5.1 C	GDSC1; GDSC2	0.1532	4.5925	-2.1698	13.1639
KYSE-50	GDSC1; GDSC2	0.921	4.232	-1.4062	6.5446

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
COLO 684	GDSC1; GDSC2; CTRP2	-0.4318	6.8277	-1.4989	39.128

Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Autonomic Ganglia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
CHP-212	GDSC1; GDSC2; CTRP2; CCLE	-4.3871	-2.4096	-4.3871	62.8219
KP-N-SI9s	CTRP2; CCLE	-2.82	-1.0581	-2.8201	52.3936
NB69	GDSC1; GDSC2	-2.0632	-0.4876	-2.1397	21.0981
NB1	GDSC1; GDSC2; CTRP2	-1.6992	1.4424	-1.7246	44.9825
GOTO	GDSC1; GDSC2	-1.3116	1.1872	-1.868	16.2865
KP-N-YS	GDSC1; GDSC2	-0.841	1.2036	-1.3932	11.6149
SJNB-13	GDSC1; GDSC2	-0.8176	2.3376	-1.9045	14.6421
GI-ME-N	GDSC1; GDSC2	-0.7423	3.3539	-2.3296	16.9277
KP-N-RT-BM-1	GDSC2	-0.5113	5.1823	-3.0286	20.0475
SJNB-5	GDSC1; GDSC2	-0.3516	1.2446	-0.935	7.0282
SK-N-BE(2)-M17	GDSC1; GDSC2	-0.2605	1.5545	-1.0037	7.155
SJNB-17	GDSC1; GDSC2	-0.2596	2.1521	-1.2994	9.0123
SK-N-MC-IXC	GDSC1; GDSC2	-0.0938	2.9791	-1.5684	10.1942
SJNB-10	GDSC1; GDSC2	-0.0809	2.1584	-1.1474	7.5027
SJNB-7	GDSC1; GDSC2	0.0986	2.2114	-1.0246	6.2057
NH-12	GDSC1; GDSC2	0.1574	4.0173	-1.8791	11.3924
MHH-NB-11	GDSC1; GDSC2; CTRP2	0.336	2.8594	0.2986	31.4928
CHP-134	GDSC1	0.5887	5.2183	-2.1363	14.3897
SK-N-FI	GDSC1; GDSC2; CTRP2; CCLE	0.5982	2.2378	0.5944	29.634
NB(TU)1	GDSC1; GDSC2	0.6125	3.4239	-1.2322	6.1878
SJNB-12	GDSC1; GDSC2	0.6735	5.9016	-2.4101	13.1385
SK-N-DZ	GDSC1; GDSC2; CTRP2; CCLE	0.7162	4.9307	0.3514	30.0593
IMR-5	GDSC1; GDSC2	0.8674	2.9383	-0.8245	3.1718
SK-N-SH	GDSC1; GDSC2; CTRP2; CCLE	0.9059	2.9799	0.8827	27.649
LA-N-6	GDSC1; GDSC2	1.0534	3.6829	-1.055	4.1649
SK-N-AS	GDSC1; GDSC2; CTRP2; CCLE	1.1337	5.9043	0.5142	28.1772
SiMa	GDSC1; GDSC2; CCLE	1.2181	3.216	0.9924	14.6681
IMR-32	CTRP2; CCLE	1.3538	4.3585	1.1811	25.1782
SJNB-14	GDSC1; GDSC2	1.4178	3.671	-0.832	2.304
Kelly	GDSC1; GDSC2; CTRP2; CCLE	1.7504	5.4802	1.3217	23.4516
TGW	GDSC1; GDSC2	1.7745	3.4211	-0.5538	0.6735
SJNB-6	GDSC1; GDSC2	1.9873	3.5995	-0.5326	0.475
NH-6	CTRP2	2.5242	5.9035	2.0194	18.6056
SK-N-BE(2)	CTRP2; CCLE	2.9254	10.6324	0.3345	23.7214
CHP-126	GDSC1; GDSC2; CTRP2	3.0273	7.1436	2.0538	17.0855
KP-N-YN	GDSC1; GDSC2; CTRP2	4.093	9.2925	2.0834	14.3716

Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Biliary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SNU-308	CTRP2	-0.5329	4.3564	-0.8692	38.107
HuCC-T1	GDSC1; GDSC2; CTRP2; CCLE	-0.0715	6.4308	-0.9706	36.6204
SNU-478	CTRP2	0.6298	3.231	0.5742	29.5971
SNU-1196	CTRP2	2.7965	12.242	-0.5647	26.8727
HuH-28	CTRP2	5.5314	12.7898	1.5696	13.4915
SNU-869	CTRP2	8.5611	20.1836	0.1673	13.5785

Cancer Drug Sensitivity Data Curated from 92 Cell Line(s) in Breast Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MDA-MB-361	GDSC1; GDSC2; CTRP2	-5.3563	-2.4357	-5.3573	69.0257
MDA-MB-330	GDSC1; GDSC2	-4.3485	3.688	-6.0884	46.2381
MDA-MB-453	GDSC1; GDSC2; CTRP2; CCLE	-3.7984	1.2213	-3.8917	58.2353
Evsa-T	GDSC1; GDSC2	-3.3851	0.6599	-3.8935	36.1852
DU4475	GDSC1; GDSC2; CTRP2	-3.3261	-1.8917	-3.3261	55.765
HCC1806	GDSC1; GDSC2; CTRP2; CCLE	-3.2453	-0.5747	-3.248	55.2069
COLO 824	GDSC1; GDSC2	-2.9971	1.4443	-3.7538	33.5908
CAL-148	GDSC2	-2.5994	0.0805	-2.8592	27.4294
HCC2157	GDSC1; GDSC2	-2.1733	0.3162	-2.4651	23.356
UACC-893	GDSC1; GDSC2	-2.0744	6.9766	-5.3386	34.6791
EFM-192A	GDSC1; GDSC2	-2.0242	6.672	-5.1434	33.9599
MDA-MB-175-VII	GDSC1; GDSC2; CCLE	-1.9787	4.3954	-2.8696	40.717
MFM-223	GDSC1; GDSC2	-1.9426	2.865	-3.2567	26.5087
CAL-51	GDSC1; GDSC2; CTRP2	-1.8878	1.7848	-1.9398	46.2696
HCC38	GDSC1; GDSC2; CTRP2	-1.848	3.8275	-2.1835	46.3448
Hs 578T	GDSC1; GDSC2; CTRP2; CCLE	-1.5433	8.6978	-3.3914	45.9315
UACC-812	GDSC2; CTRP2; CCLE	-1.5367	9.4058	-3.6659	46.0839
MDA-MB-415	GDSC1; GDSC2; CTRP2; CCLE	-1.4235	5.6406	-2.1856	44.3266
ZR-75-1	CTRP2; CCLE	-1.2637	6.5374	-2.2985	43.7667
HMC-1-8	CTRP2; CCLE	-1.1977	3.5005	-1.4169	42.1006
HCC1569	GDSC1; GDSC2; CCLE	-1.0907	4.2204	-1.8485	34.2339
HCC2218	GDSC1; GDSC2; CTRP2	-0.9812	8.8984	-2.8746	43.3009
HCC1954	GDSC1; GDSC2; CTRP2; CCLE	-0.6894	2.951	-0.7904	38.5021
EFM-19	GDSC1; GDSC2; CCLE	-0.273	4.2403	-0.9736	28.0354
HCC70	GDSC1; GDSC2; CCLE	-0.259	4.3751	-1.0083	28.1193
AU565	GDSC1; GDSC2; CTRP2; CCLE	-0.2123	11.2384	-3.067	40.8468
HDQ-P1	GDSC1; GDSC2; CTRP2; CCLE	-0.1775	5.197	-0.6968	36.3152
Hs 739.T	CCLE	-0.0392	3.5986	-0.4976	28.127
SK-BR-3	CTRP2; CCLE	-0.0051	17.5692	-5.8003	42.8874
MDA-MB-157	GDSC1; GDSC2; CTRP2; CCLE	0.0107	4.9783	-0.4311	34.8974
HCC1599	GDSC2	0.051	2.3155	-1.1155	6.9155
OCUB-M	GDSC1; GDSC2	0.1478	1.4509	-0.6063	3.4298
HCC1143	GDSC1; GDSC2; CTRP2	0.1545	4.9641	-0.2704	33.9186
MCF-7	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	0.1723	5.2733	-0.3369	34.0544
YMB-1-E	GDSC2	0.2789	3.9136	-1.7295	10.1318
BT-474	GDSC1; GDSC2; CTRP2; CCLE	0.2806	9.8329	-1.9452	37.4691
BT-549	GDSC1; GDSC2; CTRP2; CCLE	0.392	9.9846	-1.8963	37.012
MRK-nu-1	GDSC1; GDSC2	0.3965	1.8901	-0.6385	3.0249
CAL-85-1	GDSC1; GDSC2; CTRP2; CCLE	0.6078	5.1806	0.1647	31.0259
MDA-MB-436	GDSC1; GDSC2; CCLE	0.6878	8.117	-1.6716	27.3961
HCC1500	GDSC1; GDSC2; CTRP2	0.9219	8.6696	-0.782	32.7717
BT-483	GDSC1; GDSC2	0.9821	7.4299	-2.9316	15.197
HCC1187	GDSC1; GDSC2; CCLE	1.2133	4.2069	0.626	16.2855
HCC202	GDSC1; CTRP2	1.3107	9.9939	-0.9625	32.0452
MDA-MB-231	GDSC1; GDSC2; CTRP2	1.3368	4.1443	1.2037	25.1542
ZR-75-30	GDSC1; GDSC2; CTRP2; CCLE	1.7361	9.5496	-0.3321	29.0515
JIMT-1	GDSC1; GDSC2; CTRP2	1.8043	9.7362	-0.3478	28.9023
HCC1937	GDSC1; GDSC2; CTRP2	1.9733	9.0877	0.116	26.989
MDA-MB-468	GDSC1; GDSC2; CTRP2; CCLE	2.6058	6.3746	1.9304	18.7085
CAMA-1	GDSC1; GDSC2; CTRP2; CCLE	2.714	15.9551	-2.457	31.7171
T-47D	GDSC1; GDSC2; CTRP2; CCLE	3.2262	7.8396	1.9445	16.9982
BT-20	GDSC1; GDSC2; CTRP2; CCLE	4.9635	18.9432	-1.9726	25.777
KPL-1	CTRP2	5.4044	7.5609	4.0721	3.4426
CAL-120	GDSC1; GDSC2; CTRP2	5.6552	7.7896	4.1415	2.7659
Hs 578Bst	CTRP2	5.7415	7.2947	4.4335	1.4928
HCC1395	GDSC1; GDSC2; CTRP2; CCLE	5.83	14.9967	0.7068	16.1482
HCC1419	GDSC1; GDSC2; CTRP2	7.1927	18.976	-0.2222	16.8924
HCC1428	GDSC1; GDSC2; CTRP2	7.3069	23.0037	-2.1265	21.9844
BT 139	CTRP2	-6.7549	-4.985	-6.7549	78.5096
BT 172	CTRP2	-6.3433	-3.8644	-6.3434	75.5694
BT 504	CTRP2	-6.2218	-3.1092	-6.2228	74.4119
BT147	CTRP2	-6.1323	-0.0058	-6.2318	70.6073
BT 444	CTRP2	-4.7932	-0.113	-4.8349	64.4798
BT 179	CTRP2	-4.5449	4.5934	-5.301	59.8607
BT 271	CTRP2	-4.4074	-0.4093	-4.4274	62.4776
BT 239	CTRP2	-3.9824	-0.2897	-3.9979	59.8758
BT 416	CTRP2	-3.6111	-2.5099	-3.6111	57.6642
BT 440	CTRP2	-3.2857	0.0953	-3.2993	55.4091
BT 232	CTRP2	-3.0403	0.4551	-3.06	53.7917
BT 428	CTRP2	-3.006	0.0036	-3.0137	53.6022
BT 216	CTRP2	-2.8761	1.696	-2.9666	52.6204
BT 286	CTRP2	-2.8103	1.5802	-2.8873	52.2224
BT 224	CTRP2	-2.7296	1.5818	-2.8029	51.7147
BT 187	CTRP2	-2.0718	5.8726	-2.9628	47.9878
BT 145	CTRP2	-1.9318	2.777	-2.0911	46.6845
BT 330	CTRP2	-1.8877	3.6329	-2.1874	46.5518
BT 131	CTRP2	-1.7893	2.814	-1.944	45.7728
BT 328	CTRP2	-1.5773	3.0888	-1.7574	44.4576
BT 248	CTRP2	-0.7347	6.6694	-1.7706	40.8104
BT 482	CTRP2	-0.671	3.9365	-0.9292	38.7981
BT 228	CTRP2	-0.5306	5.209	-1.0855	38.6244
BT164	CTRP2	-0.5162	5.0064	-1.0137	38.3993
BT 112	CTRP2	0.2418	2.3067	0.2305	32.033
BT 422	CTRP2	0.8407	11.503	-2.1209	36.0421
BT 159	CTRP2	1.0234	7.9243	-0.365	31.2974
BT 340	CTRP2	1.2044	8.3105	-0.3359	30.6477
BT 320	CTRP2	1.4602	14.7638	-3.0507	35.9503
BT 245	CTRP2	1.6956	9.4195	-0.3145	29.1163
BT 231	CTRP2	2.3748	9.403	0.3759	25.0223
BT 333	CTRP2	2.8703	12.0236	-0.3892	26.1681
BT 359	CTRP2	4.4895	17.898	-1.8505	26.4331
BT 498	CTRP2	6.7329	24.9284	-3.5278	26.0075

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Tongue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
YD-38	CTRP2	-2.1076	0.9719	-2.1245	47.6699

Cancer Drug Sensitivity Data Curated from 68 Cell Line(s) in Central Nervous System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KS-1 [Human Krukenberg tumour]	GDSC1; GDSC2	-5.5687	-2.9463	-5.5909	55.6971
D-336MG	GDSC1; GDSC2	-5.0075	-1.1206	-5.2047	50.2226
H4	GDSC1; GDSC2; CCLE	-4.7588	-1.9263	-4.7651	59.6946
42-MG-BA	GDSC1; GDSC2; CTRP2; CCLE	-4.1816	7.4172	-5.7593	56.9687
D-566MG	GDSC1; GDSC2	-3.7068	-1.3336	-3.7745	37.5102
M059J	GDSC1; GDSC2; CCLE	-3.581	-0.2695	-3.6188	50.7395
D-247MG	GDSC1; GDSC2	-3.4047	-1.2417	-3.4648	34.4603
YH-13	GDSC1; GDSC2; CTRP2	-3.2427	-1.5807	-3.2428	55.2094
Hs 683	GDSC1; GDSC2; CTRP2; CCLE	-3.0926	0.2619	-3.1073	54.1468
LN-18	GDSC1; GDSC2; CTRP2; CCLE	-3.033	-1.4393	-3.033	53.8125
SK-MG-1	GDSC1; GDSC2	-2.8255	-0.5113	-2.9605	29.0413
SF539	GDSC1; GDSC2; CTRP2	-2.6663	-0.4123	-2.6674	51.368
GaMG	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-2.4855	0.966	-2.5087	50.6958
AM-38	GDSC1; GDSC2; CTRP2	-2.3452	-0.2381	-2.3461	49.2311
GI-1	GDSC1; GDSC2; CCLE	-2.0676	1.257	-2.1703	39.4268
MOG-G-CCM	GDSC1; GDSC2; CCLE	-2.065	2.0848	-2.3073	39.8107
SF295	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-2.0351	1.2099	-2.0568	47.7659
LN-229	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.8947	1.7173	-1.9423	46.3085
MOG-G-UVW	GDSC1; GDSC2	-1.7051	-0.0864	-1.838	17.8075
D-245MG	GDSC2	-1.651	0.5332	-1.9711	18.3004
KINGS-1	GDSC1; GDSC2	-1.6243	2.3954	-2.723	22.4371
CCF-STTG1	CTRP2	-1.5903	2.6277	-1.7077	44.4364
Becker	GDSC1; GDSC2; CTRP2	-1.4426	3.6156	-1.7024	43.7333
YKG-1	GDSC1; GDSC2; CTRP2; CCLE	-1.4075	3.4462	-1.6337	43.4537
U-251MG	GDSC1; GDSC2; CTRP2	-1.3807	1.0615	-1.3875	42.8243
U-118MG	GDSC1; GDSC2; CTRP2; CCLE	-1.2955	4.5793	-1.7533	43.1452
1321N1	CCLE	-0.9753	3.7741	-1.572	36.3525
T98G	GDSC1; GDSC2; CTRP2; CCLE	-0.9601	3.1556	-1.1061	40.3969
KNS-81-FD	GDSC1; GDSC2	-0.955	3.0015	-2.3556	17.8238
D-263MG	GDSC1; GDSC2	-0.9372	3.2407	-2.4551	18.3377
LNZTA3WT4	GDSC1; GDSC2	-0.9085	2.4876	-2.0634	15.9257
LN-405	GDSC1; GDSC2	-0.6555	4.5467	-2.8404	19.5238
U-87MG ATCC	GDSC1; CTRP2; CCLE	-0.6018	4.8374	-1.0622	41.4279
D-423MG	GDSC1; GDSC2	-0.3564	2.445	-1.5309	10.7746
PFSK-1	GDSC1	-0.3179	2.0518	-1.3015	11.4664
Onda 11	GDSC1; GDSC2	-0.2901	3.3487	-1.9219	12.991
SW1088	GDSC1; GDSC2; CTRP2; CCLE	-0.2651	7.1075	-1.4203	38.3424
D-392MG	GDSC1; GDSC2	0.0502	3.377	-1.6468	10.2612
DBTRG-05MG	GDSC1; GDSC2; CTRP2; CCLE	0.115	5.098	-0.35	34.2922
Onda 10	GDSC1; GDSC2	0.2991	11.2544	-5.38	27.1931
SNB-75	GDSC1; GDSC2; CTRP2	0.3598	7.2357	-0.7978	34.6647
KALS-1	GDSC1; GDSC2; CTRP2; CCLE	0.397	6.529	-0.4984	33.7343
KNS-60	CTRP2; CCLE	0.4058	2.8752	0.3701	31.0224
SF268	GDSC1; GDSC2; CTRP2	0.4539	6.3899	-0.388	33.2283
8-MG-BA	GDSC1; GDSC2; CTRP2; CCLE	0.5246	3.3883	0.4458	30.3753
A-172	GDSC1; GDSC2; CTRP2; CCLE	0.5268	6.1093	-0.2129	32.4693
DK-MG	GDSC1; GDSC2; CTRP2; CCLE	0.5661	6.503	-0.3066	32.6144
GMS-10	CTRP2; CCLE	0.6721	4.7054	0.3609	30.1724
D-502MG	GDSC1; GDSC2	0.7337	3.701	-1.2804	6.2014
D-542MG	GDSC1; GDSC2	0.7559	4.3178	-1.5659	7.8998
M059K	CTRP2	1.0966	2.6333	1.0917	26.3173
Daoy	GDSC1; GDSC2; CTRP2; CCLE	1.2062	4.982	0.8726	26.7185
KG-1-C	CTRP2	1.3776	15.482	-3.4751	36.8336
SNU-201	CTRP2	1.4318	6.5607	0.6043	26.9496
TM-31	CTRP2	1.8002	3.8028	1.7497	21.7839
D283 Med	GDSC1; GDSC2; CTRP2	1.9037	7.4649	0.7488	25.0517
ONS-76	GDSC1; GDSC2; CTRP2; CCLE	2.1629	5.4031	1.7949	20.4962
SF126	GDSC1; GDSC2; CTRP2; CCLE	2.1664	3.9029	2.126	19.3098
NMC-G1	GDSC1; GDSC2; CTRP2	2.4198	11.0878	-0.37	27.2743
CAS-1	GDSC1; GDSC2; CTRP2; CCLE	2.4789	7.8466	1.183	21.8747
GOS-3	CTRP2	2.7421	11.4598	-0.2382	26.0348
GB-1	GDSC1; GDSC2; CTRP2; CCLE	3.089	7.1879	2.0979	16.7506
KNS-42	GDSC1; GDSC2; CTRP2; CCLE	4.0731	11.775	0.8389	19.2241
KNS-81	CTRP2; CCLE	4.5775	11.2897	1.5246	15.5478
SNU-1105	CTRP2	4.9877	13.092	0.9732	17.8593
SW1783	GDSC1; GDSC2; CTRP2	5.6282	15.7767	0.1567	18.4114
SNU-626	CTRP2	6.0276	16.0418	0.342	17.0527
SNU-489	CTRP2	8.0683	20.1033	-0.138	15.2623

Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
ETK-1	GDSC1; GDSC2	-2.3826	2.2226	-3.4216	29.2055
TGBC24TKB	GDSC1; GDSC2	-0.3978	4.7259	-2.7021	17.9177
TGBC1TKB	GDSC1; GDSC2	-0.2946	7.5709	-4.0337	24.0755

Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Endometrium Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
AN3-CA	GDSC1; GDSC2; CTRP2; CCLE	-3.8733	0.0568	-3.8976	59.1032
JHUEM-2	CTRP2; CTRP1; CCLE	-3.8601	-1.9619	-3.8601	59.3182
HEC-265	CTRP2; CTRP1; CCLE	-3.0294	-1.616	-3.0294	54.2916
MFE-280	GDSC1; GDSC2; CCLE	-0.7547	2.3869	-0.948	29.7134
ESS-1	GDSC1; GDSC2; CTRP2; CCLE	-0.5972	3.7715	-0.8175	38.2208
MFE-296	GDSC1; GDSC2; CTRP2; CCLE	-0.2195	3.4968	-0.3637	35.5241
JHUEM-1	CTRP2	0.1575	2.9705	0.1024	32.7396
TEN	CCLE	0.2154	4.3	-0.4718	27.0013
HEC-1-A	CTRP2; CCLE	0.226	7.445	-1.0206	35.6823
HEC-151	CTRP2; CTRP1; CCLE	0.2899	1.8428	0.2882	31.6806
HEC-251	CTRP2; CTRP1; CCLE	0.4088	6.6073	-0.4684	34.2847
JHUEM-7	CTRP2	0.4674	2.9697	0.4272	30.6269
HEC-1-B	CTRP2; CCLE	0.5925	10.3229	-1.8397	36.2586
MFE-319	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	0.755	6.9288	-0.2099	32.4008
HEC-6	CTRP2; CTRP1; CCLE	0.7726	6.1482	0.082	31.4739
HEC-50B	CTRP2	1.11	8.6012	-0.5573	31.5724
RL95-2	GDSC1; GDSC2; CTRP2; CCLE	1.6168	11.1478	-1.1846	31.713
HEC-59	CTRP2; CTRP1; CCLE	1.6497	6.529	0.8985	26.063
JHUEM-3	CTRP2	1.746	5.0747	1.4364	23.0539
KLE	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.749	5.0019	1.4876	23.6989
EN	GDSC1; GDSC2; CTRP2; CCLE	2.6045	10.8259	-0.0667	25.8566
EFE-184	CTRP2; CCLE	2.6483	7.5751	1.4757	20.3203
HEC-108	CTRP2; CTRP1	4.9191	9.7096	2.7131	10.9314
Ishikawa (Heraklio) 02 ER-	CTRP2; CTRP1; CCLE	-2.8395	-1.0322	-2.8396	53.0395

Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Kidney Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KTCTL-140	GDSC1; GDSC2	-3.9515	-1.0026	-4.0859	40.1932
LB1047-RCC	GDSC1; GDSC2	-3.4506	0.774	-4.0023	36.9525
BB65-RCC	GDSC1; GDSC2	-2.9541	0.7917	-3.4702	32.1518
SN12C	GDSC1; GDSC2	-2.7464	0.309	-3.087	29.2963
RXF 393L	GDSC1; GDSC2	-2.565	2.0224	-3.5272	30.5228
KTCTL-195	GDSC1; GDSC2	-2.452	0.6208	-2.868	26.7831
BFTC-909	GDSC1; GDSC2; CTRP2; CCLE	-2.1765	3.1462	-2.4106	48.2702
786-O	GDSC1; GDSC2; CTRP2; CCLE	-1.8209	0.7891	-1.8283	45.7539
LB996-RCC	GDSC1; GDSC2	-1.6968	-0.1208	-1.8203	17.6739
LB2241-RCC	GDSC1; GDSC2	-1.6817	1.1615	-2.2449	19.9853
KTCTL-26A	GDSC1; GDSC2	-1.4189	0.6296	-1.7567	16.0853
HA7-RCC	GDSC1; GDSC2	-1.0762	2.6814	-2.3171	18.0372
769-P	GDSC1; GDSC2; CTRP2; CCLE	-0.317	4.714	-0.7198	36.8971
KTCTL-21	GDSC1; GDSC2	-0.1227	2.6888	-1.448	9.5247
SW156	GDSC1; GDSC2	-0.053	2.1392	-1.1141	7.2089
NCC010	GDSC1; GDSC2	0.0271	2.0119	-0.9835	6.1482
TK-10	GDSC1; GDSC2	0.0495	4.7775	-2.3476	14.5155
KTCTL-13	GDSC1; GDSC2	0.0944	2.5767	-1.2105	7.3927
KTCTL-1M	GDSC1; GDSC2	0.3008	2.5475	-1.0326	5.7133
A-704	GDSC1; GDSC2	0.3149	2.2798	-0.8892	4.7783
SW13	GDSC1; GDSC2	0.6068	3.674	-1.3591	6.9866
NCC021	GDSC1; GDSC2	0.6415	2.1997	-0.6222	2.4183
KMRC-1	GDSC1; GDSC2; CTRP2; CCLE	1.4822	7.1496	0.4318	27.3827
TUHR4TKB	CTRP2	2.0235	6.861	1.1204	23.3771
KMRC-20	GDSC1; GDSC2; CTRP2	2.5788	11.5525	-0.4389	27.0615
OS-RC-2	GDSC1; GDSC2; CTRP2	3.054	12.1765	-0.2912	25.413
A-498	GDSC1; GDSC2; CTRP2	3.0752	11.8278	-0.1016	24.7709
CAL-54	GDSC1; GDSC2; CTRP2	3.4368	9.266	1.4797	18.2925
ACHN	GDSC1; GDSC2; CTRP2; CCLE	4.0887	9.2538	2.0984	14.3207
UO-31	GDSC1; GDSC2; CTRP2	4.1709	13.7182	-0.0403	22.0234
VMRC-RCW	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	4.1847	8.8185	2.4931	13.3983
TUHR10TKB	CTRP2	5.8098	11.526	2.4173	9.6105
KMRC-2	CTRP2; CCLE	6.012	11.5778	2.5449	8.7494
RCC10RGB	GDSC1; GDSC2; CTRP2; CTRP1	6.214	8.0411	4.3719	1.214
VMRC-RCZ	GDSC1; GDSC2; CTRP2; CCLE	6.2326	13.0544	1.9814	10.6435
SNU-1272	CTRP2	7.4275	16.7877	1.0207	12.3555
Caki-1	GDSC1; GDSC2; CTRP2	7.6894	12.2287	3.3436	3.3729
TUHR14TKB	CTRP2	7.7625	10.0214	4.2959	1.0092
Caki-2	CTRP2; CCLE	10.2347	23.0468	-0.0862	12.1671

Cancer Drug Sensitivity Data Curated from 62 Cell Line(s) in Large Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SW48	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-5.2171	-3.2373	-5.2172	68.6776
COLO205	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-4.2931	-0.3011	-4.3125	62.1666
GP2d	CTRP2; CTRP1	-4.11	-0.1424	-4.1306	61.0247
CaR-1	GDSC1; GDSC2	-3.9761	-1.219	-4.0775	40.3135
SNU-175	GDSC2; CTRP2; CTRP1	-3.7877	1.6187	-3.92	58.0073
SK-CO-1	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-3.7733	-1.8416	-3.7734	59.1886
COLO201	CTRP2; CCLE	-3.4325	-0.7331	-3.4349	56.4423
GP5d	GDSC1; GDSC2	-3.1599	-1.305	-3.199	31.9056
CL-34	CTRP1	-3.1325	-0.1273	-3.3522	48.0228
SW620	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-3.0932	-0.079	-3.1005	54.1775
NCI-H508	GDSC1; GDSC2; CTRP2; CTRP1	-3.0555	1.5627	-3.1428	53.7433
KM12	GDSC1; GDSC2; CTRP2; CTRP1	-2.7728	-0.1343	-2.7764	52.0711
DiFi	GDSC1; GDSC2	-2.6056	2.352	-3.7083	31.4979
LS513	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-2.5981	-0.7896	-2.5983	51.4492
RKO	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-2.4487	-0.4469	-2.4492	49.9201
NCI-H747	GDSC1; GDSC2; CTRP2; CCLE	-2.3917	1.9923	-2.4855	49.5612
SW403	CTRP1; CCLE	-2.1337	6.6431	-3.2372	52.1032
HCC2998	GDSC1; GDSC2	-2.1218	0.7004	-2.5386	23.5241
SNU-1040	CTRP1	-2.1192	0.4365	-2.3982	35.0302
CL-40	CTRP1	-1.7199	-0.5318	-1.7498	27.7254
LS180	GDSC1; GDSC2; CTRP2; CTRP1	-1.572	2.4077	-1.6635	44.2713
HT-29	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.4421	3.7568	-1.7291	43.7751
HCT 116	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.3964	0.3286	-1.3968	42.9108
SNU-C5	GDSC1; GDSC2; CTRP2; CTRP1	-1.3856	2.2905	-1.4558	43.0077
LS411N	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.3074	2.3066	-1.3688	43.0924
CCK-81	GDSC1; GDSC2; CTRP2; CCLE	-0.7219	4.0588	-1.0094	39.1996
SW837	GDSC1; GDSC2	-0.6863	2.9827	-2.0958	15.3449
SW948	GDSC1; GDSC2; CTRP2; CTRP1	-0.6734	3.9893	-0.9424	38.841
HT115	GDSC1; GDSC2; CTRP1	-0.6665	1.583	-1.298	12.1509
NCI-H716	GDSC1; GDSC2; CTRP2	-0.6644	7.3958	-1.9555	40.8471
SW626	GDSC1; GDSC2	-0.6355	3.2639	-2.1877	15.7245
MDST8	GDSC1; GDSC2; CTRP2; CTRP1	-0.5447	2.2232	-0.5742	37.3297
SNU-C1	GDSC1; GDSC2; CTRP2	-0.4984	2.9358	-0.5861	37.1989
SW480	CTRP1; CCLE	-0.4483	5.2715	-1.5584	33.9466
HCT 15	GDSC1; GDSC2; CTRP2; CCLE	-0.3042	3.8193	-0.5097	36.264
SW1417	GDSC1; GDSC2; CTRP2; CCLE	-0.2177	5.6266	-0.8672	36.9042
T84	GDSC1; GDSC2; CTRP2; CCLE	-0.0418	3.4477	-0.166	34.2865
SNU-61	GDSC1; GDSC2; CTRP2; CTRP1	-0.0025	4.6341	-0.3571	34.7293
HT-55	GDSC1; GDSC2; CTRP2; CTRP1	0.0179	7.1543	-1.1336	36.683
RCM-1 [Human ESC]	GDSC1; GDSC2; CTRP2; CTRP1	0.055	5.3946	-0.5002	34.9351
SNU-81	GDSC1; GDSC2; CTRP2; CTRP1	0.146	3.9456	-0.0465	33.2597
SNU-C2B	GDSC1; GDSC2; CCLE	0.156	4.2362	-0.5114	24.6783
LoVo	GDSC1; GDSC2; CTRP2; CTRP1	0.2088	3.8513	0.0385	32.7732
SW1116	GDSC1; GDSC2	0.7078	2.9962	-0.9571	4.2844
SNU-407	GDSC1; GDSC2; CTRP2	0.7143	3.9547	0.5655	29.3488
SNU-C2A	CTRP2; CTRP1; CCLE	0.8084	11.115	-1.9033	38.0942
COLO 320HSR	GDSC1; GDSC2	1.1261	3.4263	-0.8905	3.0826
SNU-283	GDSC2	1.1844	5.474	-1.8238	8.4602
LS123	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.2002	5.715	0.6485	27.5118
SW1463	GDSC1; GDSC2; CTRP2	1.2085	4.9639	0.8799	26.6858
SNU-C4	CTRP2; CTRP1	1.2393	6.3205	0.4847	27.9473
HCT 8	CTRP2; CTRP1	1.2867	5.673	0.7561	26.8713
LS1034	GDSC1; GDSC2; CTRP2	1.3508	4.3768	1.1742	25.2118
CL-11	GDSC1; GDSC2; CTRP2	1.495	5.7542	0.9561	25.5311
C2BBe1	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.4962	5.4935	1.0761	25.911
COLO 320	CTRP2; CTRP1; CCLE	1.8741	5.5093	1.4472	22.6258
OUMS-23	CTRP2	1.9606	9.9106	-0.2708	28.2297
COLO 678	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	2.1494	15.856	-2.9299	33.9901
CW-2	GDSC1; GDSC2; CTRP2; CTRP1	2.173	8.3577	0.6447	24.6535
DLD-1	CTRP2; CTRP1	2.97	10.9601	0.3061	24.4333
HCC-56	CTRP2	3.0277	10.4067	0.5407	22.7572
SNU-503	CTRP2	5.1607	8.9285	3.1984	7.5362

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MO-T	GDSC1; GDSC2	0.2226	2.2223	-0.9315	5.2812

Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Liver Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JHH-5	CTRP2; CCLE	-4.412	-0.6803	-4.4249	62.6207
Hep-G2	CTRP2; CTRP1; CCLE	-3.6876	-2.1238	-3.6876	58.173
Hep-G2/C3A	GDSC1; GDSC2; CCLE	-2.4123	0.4816	-2.4549	41.8781
JHH-7	GDSC1; GDSC2; CCLE	-2.2592	1.5696	-2.4218	41.046
PLC/PRF/5	CTRP2; CCLE	-1.981	2.6868	-2.1312	46.987
HuH-1	GDSC1; GDSC2; CTRP2; CCLE	-1.945	6.2535	-2.9448	47.3772
Li-7	CTRP2	-1.6413	1.9044	-1.6917	44.6488
HLF	CTRP2; CCLE	-1.158	4.6024	-1.6091	42.2919
Hep 3B2.1-7	GDSC1; GDSC2; CTRP2; CCLE	-0.7009	1.1761	-0.7029	38.2844
SNU-878	CTRP2	-0.4057	2.2946	-0.4345	36.4022
HLE	GDSC1; GDSC2; CCLE	-0.2548	2.5386	-0.4375	25.8297
SNU-886	CTRP2	0.1302	4.1507	-0.1037	33.4943
Huh-7	GDSC1; GDSC2	0.2292	1.8682	-0.7506	4.1265
SNU-387	GDSC1; GDSC2; CTRP2; CCLE	0.2901	3.2673	0.2113	31.9352
SNU-423	GDSC1; GDSC2; CTRP2; CCLE	1.025	3.0454	1.002	26.8548
HuH-6	CTRP2	1.4773	7.4337	0.313	27.7929
JHH-1	GDSC1; GDSC2; CTRP2	2.0171	7.2919	0.9393	24.05
JHH-2	GDSC1; GDSC2; CTRP2; CCLE	2.0581	5.3357	1.7013	21.1514
SNU-182	CTRP2; CCLE	2.1027	7.3584	1.0014	23.5827
SNU-449	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	3.6006	6.4431	3.0116	12.7614
JHH-4	GDSC1; GDSC2; CTRP2; CCLE	3.6096	7.0253	2.7005	13.0221
SNU-398	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	3.9981	9.3551	1.9652	15.0622
SNU-761	CTRP2	4.1826	9.8641	1.8834	14.9772
JHH-6	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	5.9888	7.184	4.7711	0.7673
SK-HEP-1	GDSC1; GDSC2; CTRP2; CCLE	5.9995	11.8124	2.4196	9.2789
SNU-475	CTRP2; CCLE	7.704	17.6382	0.8027	12.7046

Cancer Drug Sensitivity Data Curated from 229 Cell Line(s) in Lung Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H1703	GDSC1; GDSC2; CTRP2; CCLE	-5.6402	0.8469	-5.7944	67.6139
EBC-1	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-5.4686	10.4462	-8.1993	59.6749
Lu-99	CTRP2; CTRP1; CCLE	-4.4194	-3.3376	-4.4194	63.4511
NCI-H3122	GDSC1; GDSC2	-4.4193	2.9912	-5.8744	46.4537
NCI-H23	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-4.3952	-0.4215	-4.4129	62.8147
HCC44	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-4.3174	-0.9386	-4.3236	62.5453
A-549	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-4.1576	-0.6215	-4.1671	61.4739
DV-90	CTRP2; CTRP1; CCLE	-4.0724	3.2148	-4.4536	59.041
LXF 289	GDSC1; GDSC2; CTRP2; CTRP1	-3.8232	-0.8281	-3.8268	59.4353
NCI-H1915	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-3.8222	-1.6113	-3.8225	59.5019
NCI-H1341	GDSC1; GDSC2; CTRP2; CCLE	-3.7926	1.2698	-3.89	58.1828
HCC2935	CTRP2; CTRP1; CCLE	-3.7079	5.2191	-4.5555	56.0233
NCI-H2122	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-3.5936	-2.2096	-3.5936	57.5475
NCI-H2286	CTRP2; CTRP1; CCLE	-3.581	-1.6948	-3.581	57.9231
NCI-H2795	GDSC1; GDSC2	-3.539	-1.125	-3.6234	35.9143
Lu-99A	GDSC1; GDSC2	-3.5226	-1.1399	-3.6037	35.7356
NCI-H1944	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-3.3293	1.3309	-3.4036	55.9161
EMC-BAC-1	GDSC1; GDSC2	-3.3158	-0.5276	-3.4895	34.1084
NCI-H513	GDSC1; GDSC2	-3.2406	-0.2621	-3.4686	33.6164
PC-14	GDSC1; GDSC2; CTRP2; CCLE	-3.1973	0.3826	-3.2178	54.8069
NCI-H2369	GDSC1; GDSC2	-3.0672	-0.931	-3.1468	31.1793
T3M-10	CTRP2; CTRP1; CCLE	-3.0396	1.1696	-3.0951	53.704
GLC-82	CCLE	-2.9296	3.7937	-3.7041	50.6844
NCI-H2373	GDSC1; GDSC2	-2.8424	0.5662	-3.2732	30.6781
EPLC-272H	GDSC1; GDSC2; CTRP2; CTRP1	-2.8068	1.9927	-2.9154	52.6539
NCI-H322	CTRP2; CCLE	-2.7191	5.4017	-3.5283	51.3217
Hs 229.T	CCLE	-2.6848	0.8878	-2.7805	48.886
NCI-H1339	CTRP2; CCLE	-2.6814	3.294	-2.9817	51.2951
Lu-134-A	GDSC1; GDSC2	-2.6252	-0.6303	-2.7208	26.8338
EMC-BAC-2	GDSC1; GDSC2	-2.605	0.4138	-2.9659	28.0058
RERF-LC-Sq1	GDSC1; GDSC2	-2.5904	0.8452	-3.0958	28.5953
NCI-H647	GDSC1; GDSC2; CTRP2; CCLE	-2.4717	3.8474	-2.865	50.0633
NCI-H1155	GDSC1; GDSC2; CTRP2; CCLE	-2.2591	0.3361	-2.264	48.662
MOR/CPR	CTRP2; CCLE	-2.1962	0.8326	-2.2106	48.2534
COR-L32	GDSC2	-2.1556	0.3187	-2.4466	23.175
NCI-H720	GDSC1; GDSC2	-2.1198	0.752	-2.555	23.6046
HCC15	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-2.0675	4.1157	-2.4846	47.7217
LK-2	GDSC1; GDSC2	-2.063	1.5826	-2.8186	24.78
NCI-H1048	GDSC1; GDSC2; CTRP1; CCLE	-2.0495	1.0182	-2.0648	47.8555
COLO 677	CCLE	-1.9733	0.612	-2.0072	42.8235
NCI-H1666	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.9307	11.0258	-4.687	48.3282
RERF-LC-A1	CTRP2; CCLE	-1.9021	4.3058	-2.3483	46.7693
LC-2/ad	GDSC1; GDSC2	-1.8273	0.7387	-2.2354	20.5519
NCI-H2810	GDSC1; GDSC2	-1.8147	0.7733	-2.2347	20.4932
NCI-H1650	GDSC1; GDSC2; CTRP2; CCLE	-1.7438	1.2517	-1.7624	45.2644
NCI-H2009	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.7355	2.0331	-1.7943	45.8679
SK-MES-1	GDSC1; GDSC2; CTRP2; CCLE	-1.6472	6.033	-2.5504	45.7214
COR-L303	GDSC2	-1.6314	0.3091	-1.8735	17.6683
NCI-H460	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.5682	0.9579	-1.5754	44.0729
A-427	GDSC1; GDSC2	-1.5464	3.7153	-3.2637	24.9437
NCI-H1755	GDSC1; GDSC2; CTRP2; CTRP1	-1.5172	1.8189	-1.557	43.8092
NCI-H2110	GDSC1; GDSC2; CTRP2; CTRP1	-1.5108	5.2293	-2.1608	44.6927
NCI-H1299	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.5089	1.079	-1.5167	44.2916
NCI-H1975	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.4775	9.5432	-3.6015	46.2137
HCC1588	CTRP2	-1.4623	0.7559	-1.4655	43.3576
NCI-H1734	GDSC2; CTRP2	-1.3333	2.5095	-1.4222	42.7055
NCI-H2170	GDSC1; GDSC2; CTRP2; CCLE	-1.3186	8.4359	-3.0502	44.776
NCI-H2073	CTRP1	-1.1907	1.1057	-1.6322	23.364
HCC2108	CTRP2; CTRP1	-1.1703	2.7095	-1.2718	41.6657
NCI-H2461	GDSC1; GDSC2	-1.1291	5.3507	-3.6662	25.2745
SK-LU-1	GDSC1; CTRP2; CTRP1; CCLE	-1.1136	7.0302	-2.3067	43.1497
NCI-H2347	GDSC1; GDSC2	-1.0739	5.4994	-3.689	25.1794
NCI-H841	GDSC1; GDSC2; CTRP2; CTRP1	-1.0375	4.0296	-1.346	41.2636
KNS-62	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.0268	2.5189	-1.0931	41.2739
NCI-H2228	GDSC1; GDSC2; CTRP2; CCLE	-1.0007	3.6476	-1.2307	40.8583
NCI-H510A	GDSC1; GDSC2	-0.996	1.2762	-1.5826	13.3481
NCI-H1963	GDSC2; CTRP1	-0.972	1.8679	-1.7346	15.8623
NCI-H3255	GDSC1; GDSC2; CTRP1; CCLE	-0.9391	7.1559	-2.8648	36.4165
RERF-LC-MS	GDSC1; GDSC2; CTRP2; CCLE	-0.9363	3.1191	-1.0755	40.2247
HCC1438	CTRP2	-0.8945	4.4314	-1.2804	40.5239
NCI-H2731	GDSC1; GDSC2	-0.8733	4.0317	-2.783	19.9571
SHP-77	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-0.8149	1.556	-0.8229	39.7235
NCI-H322M	GDSC1; GDSC2	-0.8137	5.8673	-3.6366	24.0367
NCI-H290	GDSC1; GDSC2	-0.7785	0.9378	-1.2103	10.2744
SW900	CCLE	-0.7453	2.1683	-0.894	32.7925
NCI-H211	GDSC1; GDSC2; CTRP2; CCLE	-0.7269	4.5255	-1.1202	39.4826
NCI-H596	GDSC1; GDSC2; CTRP1	-0.675	2.0112	-1.5058	13.4192
Lu-65	GDSC1; GDSC2; CTRP2; CTRP1	-0.5291	4.2555	-0.8209	38.6221
HARA [Human squamous cell lung carcinoma]	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-0.5103	4.737	-0.9103	38.7669
NCI-H1184	CTRP2; CCLE	-0.5	1.808	-0.5107	36.9726
NCI-H650	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-0.4935	2.3896	-0.5271	37.6875
SBC-3	GDSC1; GDSC2	-0.4916	2.7657	-1.8112	12.9567
COR-L311	GDSC2	-0.4278	1.9312	-1.3418	9.8254
NCI-H250	GDSC2	-0.4256	1.4928	-1.1251	8.4657
HCC95	CTRP2	-0.3582	5.0151	-0.8436	37.3724
Lu-135	GDSC1; GDSC2	-0.3349	4.8902	-2.7295	17.8683
NCI-H1770	GDSC1; GDSC2	-0.2687	4.1227	-2.2894	15.1395
RERF-LC-KJ	GDSC1; GDSC2; CTRP1	-0.1954	5.4225	-0.7485	37.1739
SCLC-21H	CTRP1	-0.191	3.1688	-1.6181	17.8695
NCI-H2171	GDSC2; CTRP2	-0.1897	4.2794	-0.4785	35.7558
NCI-H2087	GDSC1; GDSC2; CTRP2; CCLE	-0.1182	11.8879	-3.2613	40.7914
NCI-H522	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-0.1109	10.4186	-2.5367	40.2519
COR-L23	GDSC1; GDSC2; CTRP1; CCLE	-0.0112	2.6166	-0.1901	23.939
NCI-H2591	GDSC1; GDSC2	0.0149	3.6164	-1.7958	11.2893
COLO 668	GDSC1; GDSC2; CTRP2; CTRP1	0.0584	7.8064	-1.2859	37.4768
LCLC-97TM1	GDSC1; GDSC2; CTRP2; CTRP1	0.0868	8.0887	-1.3653	37.5424
NCI-H1573	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	0.0982	8.7447	-1.6155	38.0022
NCI-H1648	GDSC1; GDSC2; CCLE	0.1072	9.401	-2.8442	32.7569
NCI-H146	GDSC1; GDSC2; CTRP2	0.1575	1.7711	0.1557	32.5632
HCC1359	CTRP1	0.1639	1.6791	-0.5661	7.1318
LC-1/sq	GDSC1; GDSC2	0.1683	4.7486	-2.2355	13.5112
NCI-H520	GDSC1; GDSC2; CTRP2; CCLE	0.1708	6.6596	-0.7888	35.2981
IST-SL1	GDSC1; GDSC2	0.1719	2.2092	-0.9648	5.6264
NCI-H1836	GDSC1; GDSC2; CTRP1	0.1736	1.5913	-0.514	4.5573
NCI-H358	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	0.2406	9.5751	-1.8114	37.8876
HOP-62	GDSC1; GDSC2; CTRP2	0.2944	7.2639	-0.8784	35.0949
NCI-H1581	GDSC1; GDSC2; CTRP2; CCLE	0.3202	6.3871	-0.5316	34.0906
NCI-H2141	GDSC1; GDSC2; CTRP1	0.3242	2.6037	-0.896	6.504
COR-L51	CTRP2; CTRP1	0.3305	4.2414	0.0948	32.1793
HCC827	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	0.3462	3.6087	0.2257	31.7002
PaCa-3	GDSC1; GDSC2	0.3986	2.3652	-0.8691	4.4463
NCI-H1792	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	0.4802	8.1145	-0.9579	35.284
Lu-139	GDSC1; GDSC2	0.5135	3.0252	-1.1089	5.6606
NCI-H1930	CTRP1	0.5566	4.8995	0.2129	35.3989
NCI-H835	GDSC1; GDSC2	0.5614	2.6752	-0.9035	4.2796
NCI-H1437	GDSC1; GDSC2; CTRP1	0.5619	23.1741	-7.8892	43.2059
NCI-H1651	GDSC1; GDSC2; CTRP2; CCLE	0.5734	9.7735	-1.6176	35.8638
NCI-H1436	GDSC1; GDSC2	0.5993	2.8498	-0.9616	4.5505
NCI-H2595	GDSC1; GDSC2	0.6044	7.5414	-3.2796	17.9781
NCI-H1781	GDSC1; GDSC2; CTRP1	0.6093	5.7756	-2.2504	13.8692
UMC-11	GDSC1; GDSC2	0.6115	5.1254	-2.0726	11.3297
NCI-H2803	GDSC2	0.6268	2.5782	-0.8116	3.5765
NCI-H2804	GDSC1; GDSC2	0.685	4.293	-1.6058	8.3155
Ms-1	GDSC1; GDSC2	0.6918	3.2955	-1.1129	5.2695
NCI-H740	GDSC2	0.755	3.013	-0.9332	4.0401
NCI-H2227	GDSC1; GDSC2	0.7568	5.1839	-1.9914	10.4736
DMS 114	GDSC1; GDSC2; CTRP2; CCLE	0.7799	4.5518	0.5152	29.3046
SBC-1	GDSC1; GDSC2	0.8151	4.9761	-1.8457	9.4554
NCI-H1304	GDSC1	0.831	2.9666	-0.8611	4.3041
NCI-H292	GDSC1; GDSC2; CTRP2	0.8962	6.8537	-0.0795	30.851
NCI-H2135	GDSC1; GDSC2	0.9112	3.2393	-0.9378	3.7522
NCI-H2066	GDSC1; GDSC2	0.9473	4.6866	-1.6084	7.7093
HCC1195	CTRP2; CTRP1	0.9603	5.9219	0.3201	29.3733
NCI-H1876	GDSC1; GDSC2; CTRP1	0.962	2.4522	-0.3673	1.8912
CPC-N	GDSC1; GDSC2	0.9785	4.4956	-1.4938	6.9461
IST-SL2	GDSC1; GDSC2	1.0038	3.3429	-0.9273	3.5137
DMS 53	GDSC1; GDSC2; CTRP2	1.0146	5.1426	0.6193	28.1968
HCC1833	CTRP2; CTRP1	1.0385	27.7152	-9.781	43.0594
NCI-H2818	GDSC1; GDSC2	1.0489	2.9608	-0.7246	2.2883
CAL-12T	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.0704	7.8887	-0.301	30.9623
VMRC-LCD	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.1	5.4047	0.6699	28.5291
NCI-H2722	GDSC1; GDSC2	1.1059	3.1939	-0.7966	2.5916
LOU-NH91	GDSC1; GDSC2; CTRP2; CCLE	1.1516	20.0439	-5.9038	40.2361
NCI-H847	GDSC1; GDSC2	1.1591	2.8863	-0.63	1.6258
NCI-H2023	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.1673	6.9345	0.1801	29.1757
Lu-165	GDSC1; GDSC2	1.1824	3.7028	-0.9833	3.5109
NCI-H748	GDSC2	1.1843	3.7107	-0.9859	3.5219
NCI-H2106	CTRP2	1.1868	11.3586	-1.709	34.1758
LB647-SCLC	GDSC1; GDSC2	1.219	3	-0.6473	1.6325
NCI-H727	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.2692	9.0368	-0.5142	31.6233
NCI-H345	GDSC1; GDSC2	1.314	2.3168	-0.329	0.2503
NCI-H1869	GDSC1; CTRP2; CCLE	1.3507	15.7899	-3.6491	37.1589
HOP-92	GDSC1; GDSC2; CTRP2	1.3529	5.4113	0.9099	26.132
NCI-H2869	GDSC1; GDSC2	1.387	3.5264	-0.7855	2.1068
NCI-H1373	CTRP2; CTRP1; CCLE	1.3879	11.7915	-1.6319	33.978
NCI-H2196	GDSC2; CTRP2	1.3982	7.2943	0.2854	28.1229
NCI-H2405	GDSC1; GDSC2; CTRP2; CTRP1	1.4294	8.0903	0.0527	29.4969
SW1271	GDSC1; GDSC2; CTRP2; CCLE	1.4465	4.3739	1.2786	24.5448
COR-L95	GDSC1; GDSC2; CTRP2	1.4628	7.9894	0.0687	28.6272
Calu-1	CTRP2; CCLE	1.4914	10.6421	-1.0755	31.8006
NCI-H196	GDSC1; GDSC2; CTRP2	1.5066	8.0708	0.0801	28.4597
EKVX	GDSC1; GDSC2; CTRP2	1.6016	7.5004	0.4168	27.0759
COR-L321	GDSC1; GDSC2	1.6099	5.58	-1.5896	6.2034
Sq-1	CTRP2; CTRP1; CCLE	1.6179	6.4661	0.8391	25.5731
NCI-H64	GDSC1; GDSC2	1.6195	3.0737	-0.4868	0.5514
NCI-H1993	GDSC1; GDSC2	1.6441	11.6574	-4.5217	20.743
NCI-H187	GDSC1	1.6458	2.8004	-0.3756	0.2806
NCI-H810	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.6522	5.9003	1.1189	25.2879
COR-L105	GDSC1; GDSC2; CTRP2; CCLE	1.6645	3.3616	1.6453	22.5819
NCI-H661	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.7805	8.8925	0.0756	28.3855
NCI-H1694	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.7847	5.085	1.4759	22.7941
NCI-H209	GDSC1; GDSC2	1.8461	8.9707	-3.0555	13.7517
NCI-H526	GDSC1; GDSC2; CTRP2	1.8693	7.5953	0.6584	25.4669
Calu-3	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.8977	7.3871	0.8332	25.5597
NCI-H1435	GDSC1; GDSC2; CTRP2; CTRP1	1.9068	11.4745	-0.9716	30.9679
ChaGo-K-1	GDSC1; GDSC2; CTRP2; CTRP1	1.9079	10.4169	-0.4801	29.6559
NCI-H2030	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.943	9.8955	-0.2816	28.3117
HCC4006	CTRP2; CTRP1; CCLE	1.959	11.4853	-1.0063	30.3008
Calu-6	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.9596	7.8152	0.7224	25.7617
NCI-H838	GDSC1; GDSC2; CTRP2	1.969	21.5859	-5.911	38.4771
LK2	CTRP2	1.9998	9.2636	0.0634	27.0826
LC-1/sq-SF	CTRP2; CTRP1; CCLE	2.0146	9.0335	0.2532	27.1576
HCC78	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	2.1366	8.702	0.5245	25.9289
NCI-H1688	GDSC1; GDSC2	2.1507	8.6871	-2.7083	11.3063
DMS 273	GDSC1; GDSC2; CTRP2; CTRP1	2.1992	11.3305	-0.6171	29.2302
HCC33	GDSC2; CTRP1	2.3322	6.2194	1.7454	21.043
NCI-H2081	GDSC1; GDSC2; CTRP2; CTRP1	2.4334	6.2873	1.78	19.7629
NCI-H1838	GDSC1; GDSC2; CTRP2	2.471	9.323	0.5085	24.3119
NCI-H2444	GDSC1; GDSC2; CTRP2; CCLE	2.5039	8.8896	0.7405	23.4133
NCI-H1105	GDSC1; GDSC2; CTRP2; CTRP1	2.7099	6.0502	2.1654	17.5255
COR-L279	GDSC1; GDSC2; CTRP1	2.7486	5.9915	2.2759	17.897
ABC-1	GDSC1; GDSC2	2.7832	4.6988	-0.622	0.3522
NCI-H1568	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	3.006	8.7308	1.3912	20.5346
HCC366	GDSC1; GDSC2; CTRP2	3.2835	9.1583	1.3836	19.0361
NCI-H1355	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	3.32	19.5704	-3.6006	32.9228
RERF-LC-Ad2	CTRP2	3.3607	8.7887	1.634	17.8796
NCI-H1092	GDSC1; GDSC2; CTRP2; CCLE	3.6508	7.5193	2.5149	13.6628
NCI-H2029	GDSC1; GDSC2; CTRP2; CTRP1	3.7425	8.5927	2.1806	15.6757
LCLC-103H	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	3.7763	7.6845	2.6407	13.7676
NCI-H1693	GDSC1; GDSC2; CTRP2; CCLE	3.7763	8.2754	2.28	14.3067
NCI-H69	GDSC1; GDSC2; CTRP2	3.8168	13.1571	-0.0755	22.9281
NCI-H82	GDSC1; GDSC2; CTRP1	3.8607	10.9965	1.1272	19.436
NCI-H524	GDSC1; GDSC2; CTRP2	3.8871	7.2621	2.868	11.6563
NCI-H446	GDSC1; GDSC2; CTRP2	3.9076	6.9351	3.0404	10.9088
DMS 79	GDSC1; GDSC2; CTRP2	4.2083	11.6485	1.0221	18.2528
HCC2279	CTRP2	4.2385	10.009	1.8622	14.9392
NCI-H2126	CTRP2; CTRP1	4.2456	13.638	0.1673	21.8832
NCI-H2085	GDSC1; GDSC2; CTRP2; CCLE	4.4444	9.0115	2.541	11.7274
COR-L88	GDSC1; GDSC2; CTRP1	4.4661	20.0707	-2.8493	29.1895
NCI-H1563	GDSC1; GDSC2; CTRP2; CCLE	4.706	13.2473	0.6576	18.5152
DMS 454	CTRP2	4.8356	17.4797	-1.3481	24.4541
NCI-H889	CTRP2	5.0406	9.0586	3.0342	8.4537
SW1573	GDSC1; GDSC2; CTRP2; CCLE	5.2401	15.8281	-0.1852	20.2674
BEN	GDSC1; GDSC2; CTRP2; CTRP1	5.3323	10.3655	2.7331	10.0444
NCI-H2291	GDSC1; GDSC2; CTRP2	5.4501	18.4775	-1.3372	23.2214
NCI-H1395	CTRP2	5.502	7.5909	4.1294	3.0476
RERF-LC-Ad1	CTRP2	5.6686	6.8568	4.5904	0.9873
NCI-H1793	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	5.7775	17.5812	-0.5096	20.8749
LUDLU-1	CTRP2; CCLE	5.9607	14.6933	0.9607	14.9993
SBC-5	GDSC1; GDSC2; CTRP2; CCLE	6.1557	13.6291	1.6394	12.1086
IA-LM	GDSC1; GDSC2; CTRP2; CCLE	6.3443	11.9345	2.6134	7.9381
COLO 699	CTRP2; CTRP1; CCLE	6.9381	18.1642	-0.0119	17.555
NCI-H2172	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	7.3991	15.4824	1.6336	10.1615
NCI-H441	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	8.3949	18.693	0.77	11.8212
NCI-H1623	GDSC1; GDSC2; CTRP2	8.6243	20.4922	0.062	13.8245
HCC1171	CTRP2	8.8658	20.2664	0.3343	12.6186
NCI-H226	GDSC1; GDSC2; CTRP2; CCLE	9.2755	18.9377	1.2276	9.1134
NCI-H2342	GDSC1; GDSC2; CTRP2; CTRP1	10.3932	22.215	0.4017	10.4796
Hs 888.Lu	CTRP2	0.448	5.4414	-0.0856	32.3491

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
CBTCi002-A	GDSC1; GDSC2	2.0868	3.9115	-0.6086	0.6493

Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Soft Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Aska-SS	CTRP2	-1.5221	1.5593	-1.5478	43.8102
Yamato-SS	CTRP2	0.0292	6.0786	-0.7426	35.6826
MES-SA	GDSC1; GDSC2; CTRP2; CCLE	-4.5304	-2.8662	-4.5304	63.7849
A-204	GDSC1; GDSC2; CTRP2; CCLE	-4.1985	3.4637	-4.6592	59.0957
SW982	GDSC1; GDSC2; CTRP2	-4.1835	-1.9642	-4.1837	61.4563
SW684	GDSC1; GDSC2	-3.9378	0.563	-4.4633	41.2652
SK-UT-1	GDSC1; GDSC2; CTRP2	-3.7813	-1.8914	-3.7813	58.7936
G-402	GDSC1; GDSC2; CTRP2; CCLE	-3.6191	-0.1878	-3.6312	57.5806
TE 617.T	CTRP2; CCLE	-3.5705	-0.1015	-3.5839	57.2569
G-401	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-3.0511	-0.1004	-3.0568	54.4018
VA-ES-BJ	GDSC1; GDSC2	-2.9726	1.3168	-3.6794	33.1585
Tm87-16	CTRP2	-2.9662	4.5228	-3.5611	52.6955
KYM-1	GDSC1; GDSC2; CTRP2; CCLE	-2.816	0.4649	-2.8314	52.3361
SW872	GDSC1; GDSC2	-2.4746	-0.5175	-2.579	25.3703
RD	GDSC1; GDSC2; CTRP2; CCLE	-1.8492	2.7064	-1.9933	46.1417
BT-16	CTRP2	-1.6281	5.1791	-2.2747	45.3655
MFH-ino	GDSC1; GDSC2	-1.5335	1.3459	-2.1661	18.9214
TE 441.T	GDSC2; CTRP2	-1.1899	0.6308	-1.1908	41.5369
Rh41	GDSC1; GDSC2; CTRP2	-0.4842	2.7387	-0.5504	37.04
Rh18	GDSC1; CTRP2	-0.2667	3.4633	-0.4092	35.8308
HT-1080	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-0.1878	2.8563	-0.2498	35.0587
STS-0421	GDSC1; GDSC2	-0.0275	1.8248	-0.9354	6.0025
Hs 633.T	GDSC1; GDSC2	0.1403	1.697	-0.7346	4.2587
Rh30	GDSC1; GDSC2; CCLE	0.1638	2.3765	0.0499	22.3271
SK-LMS-1	GDSC1; GDSC2; CTRP2; CCLE	0.2438	2.5584	0.2219	32.0552
BT-12	CTRP2	0.6419	3.4287	0.5654	29.5865
EW-8	GDSC1; GDSC2	1.1068	4.9812	-1.6394	7.5359
TTC-709	CTRP2	1.4601	6.5397	0.6424	26.7329
RKN	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	2.0533	5.7807	1.553	21.7066
GCT	GDSC1; GDSC2; CTRP2; CCLE	2.5541	5.1043	2.31	17.4464
Hs 729.T	CTRP2; CCLE	6.3311	30.0466	-6.4013	31.3301

Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Thigh Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SYO-1	CTRP2	-0.4775	4.8669	-0.9343	38.0563
H-STS	CTRP2	0.8793	1.3845	0.8793	27.7483
P-STS	CTRP2	2.3407	6.6568	1.5377	20.9339

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
U-CH1	CTRP2	-0.3068	12.7488	-3.841	42.037

Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Ovary Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
2004	CTRP2	1.8221	4.2919	1.7009	21.8819
OV-90	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-3.8812	0.2743	-3.9147	59.0808
TOV-21G	GDSC1; GDSC2; CTRP2; CCLE	-3.4818	2.5534	-3.7178	55.9556
OC 315	CCLE	-2.9793	-1.4031	-2.9796	51.3503
DOV13	GDSC1; GDSC2; CTRP2; CCLE	-2.7923	0.722	-2.816	52.1715
A2780	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-2.5497	1.1034	-2.5839	50.5804
TYK-nu	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-2.1589	1.5211	-2.2037	48.0347
OVK18	GDSC1; GDSC2; CTRP2; CTRP1	-2.1374	1.3682	-2.1725	47.8854
Caov-3	GDSC2; CTRP2; CTRP1	-2.0828	-0.3002	-2.0831	47.4832
OC 316	CCLE	-2.077	1.2573	-2.1803	43.8825
OVKATE	GDSC1; GDSC2; CTRP1	-1.3884	1.808	-2.1331	19.759
OV7	CTRP2; CTRP1	-1.3823	2.1097	-1.4371	42.952
MCAS	CTRP2; CCLE	-1.2611	3.1724	-1.4311	42.4075
OVCAR-8	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.247	-0.2719	-1.247	41.9143
OC 314	GDSC1; GDSC2; CTRP2; CCLE	-1.024	3.342	-1.2031	40.8924
HEY A8	CTRP2; CTRP1; CCLE	-0.9412	5.9277	-1.712	42.1089
COV504	CCLE	-0.7197	6.6006	-2.3979	37.5136
ES-2	GDSC1; GDSC2; CCLE	-0.3359	1.1334	-0.345	25.7653
COV434	CTRP2; CTRP1	-0.2268	5.0439	-0.7081	36.5278
IGROV-1	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-0.1894	3.7735	-0.3774	35.4578
OVCAR-3	GDSC1; GDSC2; CCLE	-0.0302	4.1564	-0.6819	26.0194
OV56	GDSC1; GDSC2; CTRP2	0.0195	7.5708	-1.2893	37.0291
EFO-27	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	0.5391	5.7264	-0.0742	32.0073
ONCO-DG-1	CTRP2; CCLE	0.8935	5.1615	0.4819	29.0494
RMUG-S	CTRP1	0.9546	3.2074	-0.7262	5.7522
FU-OV-1	GDSC1; GDSC2; CTRP2; CCLE	1.1439	5.4927	0.6573	27.6577
SNU-840	CTRP2; CTRP1	1.4329	10.1882	-0.9269	31.5908
JHOC-5	CTRP2; CTRP1	1.4547	5.2136	1.0794	25.2192
OVMANA	CTRP1; CCLE	1.5418	5.2168	1.2048	27.7252
OVCAR-4	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.5775	5.5691	1.1056	24.7495
Caov-4	GDSC1; GDSC2	1.741	4.2263	-0.8993	2.206
SK-OV-3	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.9802	10.2679	-0.3394	29.054
JHOS-2	GDSC1; GDSC2; CTRP2; CCLE	2.1387	9.3876	0.1469	26.4262
JHOS-4	GDSC1; GDSC2; CTRP1; CCLE	2.5138	5.3465	2.2291	18.7536
TOV-112D	GDSC1; GDSC2; CTRP2; CCLE	2.67	9.194	0.7658	22.883
SNU-8	CTRP2	2.8185	8.5941	1.1907	20.9434
JHOM-1	CTRP2; CTRP1	2.9826	6.8433	2.1365	16.8831
ES2	CTRP2	3.1428	6.9753	2.2459	17.1686
EFO-21	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	3.1785	9.7212	1.098	21.1761
SNU-119	CTRP2	3.3891	11.8546	0.1775	23.1041
Kuramochi	GDSC1; GDSC2; CTRP2; CCLE	4.1321	10.8917	1.3295	17.2612
OVTOKO	GDSC1; GDSC2; CTRP2; CCLE	4.339	10.822	1.5486	15.9611
OAW42	GDSC1; CTRP2; CTRP1	4.6456	8.5972	2.9256	9.7034
OVCAR-5	GDSC1; GDSC2; CTRP2	4.8025	14.9526	-0.1127	20.915
COV644	CTRP2; CTRP1	5.06	9.1521	3.0035	8.5445
OAW28	GDSC1; GDSC2; CTRP2	5.3761	9.2106	3.2309	7.0045
COV362	CTRP2; CTRP1	5.8182	13.267	1.5588	13.0103
COV318	CTRP1; CCLE	5.8414	12.4154	2.1186	12.6399
OVSAHO	CTRP2; CCLE	6.198	10.7753	3.0742	6.742
OVISE	GDSC1; GDSC2; CTRP2	6.71	7.9554	4.6367	0.1948
RMG-I	GDSC1; GDSC2; CTRP2; CTRP1	8.0858	18.324	0.7365	12.3727

Cancer Drug Sensitivity Data Curated from 9 Cell Line(s) in Pleura Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
IST-Mes2	CCLE	-2.1671	2.4453	-2.4978	45.0462
MSTO-211H	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.3592	1.2581	-1.3687	43.3111
NCI-H28	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-0.9541	6.6782	-1.9685	42.5525
MPP 89	GDSC1; GDSC2; CTRP2; CCLE	-0.5277	4.529	-0.904	38.1749
NCI-H2452	GDSC1; GDSC2; CTRP2; CCLE	-0.1634	3.6415	-0.3266	35.2117
NCI-H2052	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	0.7128	5.6892	0.1632	31.4186
ACC-MESO-1	CTRP2	1.5457	6.815	0.63	26.5178
IST-Mes1	GDSC1; GDSC2; CTRP2; CCLE	2.181	6.4014	1.4668	21.6524
JL-1	CTRP2	5.4693	9.9311	2.9455	8.0292

Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
PC-3	GDSC1; GDSC2; CCLE	-0.0635	4.2393	-0.748	26.4026
LNCaP clone FGC	GDSC1; GDSC2; CTRP2	0.5274	5.0988	0.0999	31.5006
22Rv1	GDSC1; GDSC2; CTRP2; CCLE	0.6634	4.386	0.4257	29.9866
DU145	GDSC1; GDSC2; CTRP2; CCLE	0.7037	8.1597	-0.7978	33.5146
VCaP	GDSC1; GDSC2; CTRP2	1.7712	6.257	1.0807	24.2569
PaCa-3	CTRP2; CTRP1	2.7569	5.1417	2.5511	16.8716
NCI-H660	GDSC2; CTRP2	3.5283	8.8856	1.7497	17.0185

Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Salivary Gland Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
YD-15	CTRP2	-2.4626	1.4774	-2.5163	50.0123
A-253	GDSC1; GDSC2; CTRP2; CCLE	-0.5231	2.9272	-0.6113	37.3638

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HuTu 80	GDSC1; GDSC2	-0.1432	1.301	-0.7734	5.3295

Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Stomach Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-N87	GDSC1; CTRP2; CCLE	-6.6415	1.2118	-6.9035	70.8233
AGS	GDSC1; GDSC2; CTRP2; CTRP1	-5.3503	-2.6795	-5.3507	69.0726
HSC-39	GDSC1; GDSC2	-4.3027	-2.4504	-4.3128	43.2186
BGC-823	CCLE	-3.951	0.2067	-4.0447	58.797
SNU-1	GDSC1; GDSC2; CTRP2; CCLE	-3.7124	1.9858	-3.8838	57.4354
OCUM-1	GDSC1; GDSC2; CTRP2; CCLE	-3.4581	-0.8268	-3.4601	56.6168
Fu97	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-3.1407	5.9937	-4.129	53.625
TGBC11TKB	GDSC1; GDSC2	-3.0357	0.1189	-3.3462	31.9906
TMK-1	GDSC1; GDSC2	-3.0134	2.5155	-4.2021	35.3563
SNU-16	GDSC1; GDSC2; CTRP2; CCLE	-2.933	1.2631	-2.9907	53.0243
SNU-5	GDSC1; GDSC2	-2.8112	0.5113	-3.2215	30.2753
IM95	GDSC1; GDSC2; CTRP2; CCLE	-2.6065	-0.2216	-2.6084	50.9693
SNU-620	CTRP2	-2.5928	1.3442	-2.6426	50.8535
HGC-27	GDSC1; GDSC2; CTRP2; CCLE	-2.573	0.6904	-2.5904	50.7384
SNU-719	CTRP2	-2.1763	0.6571	-2.1858	48.1165
SK-GT-2	GDSC1; GDSC2	-1.7043	2.0391	-2.6436	22.3237
GSS	CTRP2	-1.6576	5.0597	-2.2739	45.5037
AZ-521	CCLE	-1.5405	2.6546	-1.8653	40.056
NUGC-3	GDSC1; GDSC2; CTRP2; CCLE	-1.5185	3.6433	-1.7898	44.229
GSU	CTRP2	-1.3265	1.9647	-1.3685	42.5533
SNU-668	CTRP2	-1.2543	3.5395	-1.4849	42.4853
MKN45	GDSC1; GDSC2; CTRP2; CCLE	-1.2137	3.3095	-1.4018	42.1414
ECC12	GDSC2; CTRP2	-0.7637	4.0643	-1.0559	39.4796
MKN28	GDSC1; GDSC2	-0.6277	3.9504	-2.52	17.6438
Hs 746.T	GDSC1; GDSC2; CTRP2; CCLE	-0.351	5.0065	-0.8335	37.3197
GCIY	GDSC1; GDSC2; CCLE	-0.1673	2.8759	-0.4235	25.454
RF-48	GDSC1; GDSC2	0.5419	5.444	-2.2846	12.7634
KATO III	GDSC1; GDSC2; CTRP2	0.5641	10.1087	-1.7741	36.2167
HuG1-N	CTRP2	0.9461	10.7748	-1.6835	34.8399
NUGC-4	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	0.954	8.7592	-0.7236	33.1581
KE-39	CTRP2; CCLE	1.0368	6.3915	0.2409	29.3891
RERF-GC-1B	GDSC1; GDSC2; CCLE	1.1977	3.6107	0.8381	15.4008
SNU-216	CTRP2	1.2404	8.0067	-0.1712	30.0468
SCH	GDSC1; GDSC2	1.2834	3.3833	-0.7797	2.2245
23132/87	GDSC1; GDSC2; CTRP2	1.471	12.8792	-2.1407	34.263
NCC-StC-K140	CTRP2	1.8491	6.1483	1.2039	23.5821
SNU-601	CTRP2	2.7265	6.5439	1.9913	18.1404
LMSU	CTRP2	3.2357	8.1774	1.7981	17.5488
ECC10	GDSC1; GDSC2; CTRP2	4.3528	7.9836	2.965	10.1721
MKN7	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	4.9455	10.8459	2.1683	13.0884
SH-10-TC	CTRP2; CTRP1; CCLE	5.0059	9.7633	2.7608	10.5619
MKN74	CTRP2; CTRP1; CCLE	5.2483	15.1151	0.289	19.4005
MKN1	GDSC1; GDSC2; CTRP2	5.6815	8.2647	3.9294	3.5907
SNG-M	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	1.7948	6.0031	1.2395	24.4361
SNU-685	CTRP2	3.4709	6.3413	2.8571	12.7652
SNU-1077	CTRP2	5.9683	9.8299	3.3711	5.4367

Cancer Drug Sensitivity Data Curated from 18 Cell Line(s) in Thyroid Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SW579	CTRP2; CCLE	-4.1866	-0.4994	-4.2003	61.1925
IHH-4	GDSC1; GDSC2	-4.1776	-2.7178	-4.1801	41.9343
K5	GDSC1; GDSC2	-2.0113	-0.5553	-2.0721	20.4959
HTC-C3	GDSC1; GDSC2	-1.4797	0.4037	-1.7407	16.2572
TT2609-C02	GDSC1; GDSC2; CTRP2; CCLE	-0.9736	2.7057	-1.0632	40.3432
ASH-3	GDSC1; GDSC2	-0.8814	1.6599	-1.644	13.2862
WRO	GDSC1; GDSC2	-0.4896	3.2636	-2.0559	14.4472
CGTH-W-1	GDSC1; GDSC2; CTRP2	-0.2831	3.6526	-0.4574	36.0339
KMH-2	GDSC1; GDSC2	-0.1296	1.1316	-0.6771	4.6794
8505C	GDSC1; GDSC2; CTRP2; CCLE	0.1465	3.8338	-0.0256	33.1916
8305C	GDSC1; GDSC2; CTRP2; CCLE	0.435	6.2709	-0.3673	33.2327
TT	GDSC1; GDSC2; CTRP2	0.552	4.4435	0.2917	30.7968
ML-1 [Human leukemia]	GDSC1; GDSC2; CTRP2	0.9876	6.8715	0.0118	30.2759
BHT-101	GDSC1; GDSC2; CTRP2	1.1321	3.3179	1.0938	26.1931
FTC-238	CTRP2	1.2714	4.5741	1.045	25.9129
B-CPAP	GDSC1; GDSC2; CTRP2; CCLE	1.7871	6.7865	0.8983	24.8622
CAL-62	GDSC1; GDSC2; CTRP2	2.1494	6.4713	1.4063	21.9671
FTC-133	GDSC1; GDSC2; CTRP2	9.4736	19.4974	1.091	9.3359

Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Upper Aerodigestive Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KON	GDSC1; GDSC2	-5.4935	-2.1154	-5.5775	54.7356
PCI-38	GDSC1	-4.9916	-1.9382	-5.0661	60.9798
JHU-011	GDSC1; GDSC2	-4.9141	-1.8427	-4.9949	49.3517
DOK	GDSC1; GDSC2	-4.6934	-1.9036	-4.7549	47.2122
PCI-30	GDSC1; GDSC2	-4.583	-1.1453	-4.7418	46.3123
HO-1-u-1	GDSC1; GDSC2	-4.4845	0.1938	-4.9484	45.8867
PE/CA-PJ15	GDSC1; GDSC2; CTRP2	-4.4295	-1.0702	-4.4357	62.8684
BB49-HNC	GDSC1	-4.4201	-1.9511	-4.4633	54.9549
Hs 840.T	CCLE	-4.2355	0.0744	-4.3312	60.8639
HSC-3	GDSC1; GDSC2; CTRP2	-4.1557	-1.6773	-4.1563	61.2541
FaDu	GDSC1; GDSC2; CTRP2; CCLE	-4.0846	1.7387	-4.2486	59.5514
JHU-022	GDSC1; GDSC2	-3.9933	-0.3132	-4.2766	41.0858
PCI-04B	GDSC1; GDSC2	-3.8925	-0.3465	-4.1586	40.0799
HO-1-N-1	GDSC1; GDSC2	-3.7994	-1.9323	-3.8187	38.2187
PCI-06A	GDSC1; GDSC2	-3.6896	-1.7578	-3.7156	37.1499
BB30-HNC	GDSC1; GDSC2	-3.4786	-1.1908	-3.5499	35.2515
PE/CA-PJ34 (clone C12)	CTRP2	-3.174	-0.5118	-3.1768	54.7318
OSC-19	GDSC1; GDSC2	-3.0155	-0.4119	-3.1883	31.1261
SAS	GDSC1; GDSC2	-2.9771	0.9486	-3.5498	32.6232
BICR 78	GDSC1; GDSC2	-2.7932	1.0589	-3.3912	30.9934
OSC-20	GDSC1; GDSC2	-2.7789	-1.5367	-2.7871	27.9275
YD-10B	CTRP2	-2.7465	0.9098	-2.777	51.8624
SCC-9	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-2.6858	0.5148	-2.7001	51.4821
NCI-H3118	GDSC1; GDSC2	-2.5812	0.7941	-3.0678	28.4112
BICR 10	GDSC1	-2.5053	0.1291	-2.7705	32.9126
SAT [Human HNSCC]	GDSC1; GDSC2	-2.4736	1.9452	-3.3994	29.5173
KOSC-2	GDSC1; GDSC2	-2.4632	0.2685	-2.766	26.3001
BICR 22	GDSC1; GDSC2; CTRP2	-1.9887	2.2379	-2.0856	46.9812
SCC-25	GDSC1; GDSC2; CTRP2; CCLE	-1.6374	1.2078	-1.6522	44.5505
PE/CA-PJ49	CTRP2	-1.4229	1.5598	-1.4458	43.1458
HSC-2	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.3763	1.674	-1.4003	43.4586
UPCI-SCC-090	GDSC1; GDSC2	-1.3554	2.4296	-2.4707	19.9715
SCC-4	GDSC1; GDSC2; CTRP2	-1.2499	1.3564	-1.2616	41.9674
CAL-27	GDSC1; GDSC2; CTRP2; CCLE	-1.2072	1.4112	-1.2196	41.6854
PCI-15A	GDSC1; GDSC2	-1.1255	2.2456	-2.1583	17.2845
Detroit 562	GDSC1; GDSC2; CTRP2; CCLE	-1.0337	5.7694	-1.8001	42.0843
BHY	GDSC1; GDSC2; CTRP2	-0.8772	4.0884	-1.1843	40.2406
BICR 16	CTRP2	-0.6115	4.1589	-0.9108	38.5183
YD-8	CTRP2	-0.5965	1.9512	-0.6143	37.6376
Ca9-22	GDSC1; GDSC2	-0.3906	0.8961	-0.8042	6.3538
BICR 6	CTRP2	-0.0621	3.3664	-0.1762	34.3891
BICR 56	CTRP2	0.0746	4.8059	-0.3161	34.3352
BICR 31	GDSC2; CTRP2	0.3145	2.0038	0.3113	31.5219
JHU-029	GDSC1; GDSC2	0.3457	2.3904	-0.9208	4.8988
BICR 18	CTRP2	0.4298	3.4706	0.3346	31.0607
SCC-15	GDSC1; GDSC2	0.4338	4.3447	-1.8223	10.2848
SNU-899	CTRP2	0.8284	2.712	0.816	28.129
SKN-3	GDSC1; GDSC2	0.8649	3.4033	-1.046	4.4888
LB771-HNC	GDSC1; GDSC2	1.2256	4.5102	-1.3338	5.4671
SNU-1076	CTRP2	1.4139	7.4735	0.2299	28.2568
PE/CA-PJ41 (clone D2)	CTRP2	1.4623	11.8064	-1.6442	33.2365
CAL-33	GDSC1; GDSC2; CTRP2	1.6109	4.67	1.3926	23.6278
HSC-4	GDSC2; CTRP2	1.7247	6.282	1.0216	24.6067
SNU-1066	CTRP2	1.7474	6.1374	1.098	25.9712
SNU-1041	CTRP2	2.4455	7.0618	1.4838	22.3061
SNU-46	CTRP2	2.7883	14.9918	-1.9153	30.3735

Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Urinary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
CAL-29	GDSC1; GDSC2	-4.6907	-1.8062	-4.7624	47.2011
JMSU-1	CTRP2; CCLE	-4.3893	-3.5871	-4.3893	62.849
TCCSUP	GDSC1; GDSC2; CTRP2; CCLE	-3.3283	0.4319	-3.3538	55.6321
SW780	GDSC1; GDSC2; CCLE	-2.7372	2.4902	-3.1297	44.9682
UM-UC-1	CTRP2	-2.5747	0.8919	-2.5997	50.7464
SCaBER	CTRP2; CCLE	-2.4609	2.1727	-2.5777	50.0016
VM-CUB-1	CTRP2	-2.4208	7.6846	-3.9503	49.8211
RT-4	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-2.3942	0.2662	-2.3987	50.1052
639V	GDSC1; GDSC2; CTRP2; CCLE	-2.2382	-0.409	-2.2385	48.5182
5637	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-1.8482	0.9907	-1.8591	46.5279
U-BLC1	CTRP2	-1.7886	0.8158	-1.796	45.5392
253J	CTRP2	-1.7693	1.2133	-1.7871	45.4317
RT-112	GDSC1; GDSC2; CTRP2; CCLE	-1.7385	2.5612	-1.8571	45.3967
UM-UC-3	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-0.7878	1.4376	-0.7932	39.537
HT-1376	CTRP1; CCLE; GDSC1; GDSC2; CTRP2	-0.1097	7.9675	-1.5274	38.5657
T24	GDSC1; GDSC2; CTRP2; CCLE	0.1325	6.5097	-0.7774	35.404
KU-19-19	GDSC1; GDSC2; CTRP2	0.4031	4.2738	0.1669	31.7016
647V	GDSC1; GDSC2; CTRP2	0.4908	1.8879	0.4899	30.3397
SW1710	GDSC1; GDSC2; CTRP2	1.7231	7.3269	0.6155	26.0409
BC-3C	CTRP2	2.035	7.8528	0.7222	24.77
HT-1197	GDSC1; GDSC2; CTRP2; CCLE	2.0362	8.0592	0.6346	25.0736
KMBC-2	CTRP2; CTRP1; CCLE	2.1021	7.9497	0.8145	25.0401
BFTC-905	GDSC1; GDSC2; CTRP2	2.5077	6.4632	1.7913	19.5102
J82	GDSC1; GDSC2; CTRP2; CCLE	6.7947	16.2571	0.8215	14.0654

Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HEY	GDSC1; GDSC2	-4.6322	-2.0041	-4.6809	46.593
DSH1	GDSC1; GDSC2	-4.3999	-2.3746	-4.4153	44.2087
SKN	GDSC1; GDSC2	-3.9333	0.3618	-4.3965	41.0562
C-4-I	GDSC1; GDSC2	-3.9027	-1.8962	-3.9278	39.2787
SW962	GDSC1; GDSC2	-3.8563	0.677	-4.411	40.623
ME-180	GDSC1; GDSC2	-3.7345	-0.1903	-4.0252	38.6638
CAL-39	GDSC1; GDSC2	-3.7005	-0.8203	-3.8477	37.7838
SKG-IIIa	GDSC1; GDSC2	-2.9672	1.4229	-3.7137	33.2746
OMC-1 [Human cervical carcinoma]	GDSC1; GDSC2	-2.8556	-0.7494	-2.9484	29.127
ACC-OV7	GDSC1; GDSC2	-2.6933	0.1407	-2.9789	28.4935
OVCA433	GDSC1; GDSC2	-2.6629	1.9176	-3.5866	31.2459
BPH-1	GDSC1; GDSC2	-2.578	-0.9677	-2.6203	26.0852
HEC-1	GDSC1; GDSC2	-2.4443	2.5932	-3.6456	30.4873
PWR-1E	GDSC1; GDSC2	-2.0227	0.4224	-2.3357	21.9693
SW954	GDSC1; GDSC2	-1.9941	-0.0246	-2.1695	20.9326
JEG-3	GDSC1; GDSC2	-1.9418	0.474	-2.2652	21.2204
Ca Ski	GDSC1; GDSC2	-1.8441	1.9375	-2.7421	23.4395
LB831-BLC	GDSC1; GDSC2	-1.8295	1.1578	-2.3994	21.482
DoTc2 4510	GDSC1; GDSC2	-1.7777	0.4288	-2.072	19.4209
NT2-D1	GDSC1; GDSC2	-1.6861	1.2393	-2.2813	20.2115
MS751	GDSC1; GDSC2	-1.5331	3.9937	-3.384	25.4748
SiHa	GDSC1; GDSC2	-1.4473	5.4357	-4.0015	27.8758
OVCA420	GDSC1; GDSC2	-1.321	2.3772	-2.4122	19.5051
OVMIU	GDSC1; GDSC2	-0.8222	2.7212	-2.0946	15.8073
SW756	GDSC1; GDSC2	-0.8048	3.5579	-2.4873	18.059
SiSo	GDSC1; GDSC2	-0.7653	3.0023	-2.1785	16.1121
PEO1	GDSC1; GDSC2	-0.5201	4.1449	-2.5204	17.2892
TC-YIK	GDSC1; GDSC2	-0.4473	1.6722	-1.233	9.212
PA-1	GDSC1; GDSC2	-0.3225	1.4849	-1.0258	7.4973
HT-3	GDSC1; GDSC2	-0.1844	4.5285	-2.4197	15.641
JAR	GDSC1; GDSC2	0.0398	1.0338	-0.4841	2.9515
NEC8	GDSC1; GDSC2	0.1072	1.8875	-0.8559	5.1153
JHOS-3	GDSC1; GDSC2	0.1706	3.8555	-1.7875	10.7911
HeLa	GDSC1; GDSC2; CTRP2	0.3673	5.0755	-0.0684	32.5699
OV17R	GDSC1; GDSC2	0.5136	2.2307	-0.7218	3.275
C-33 A	GDSC1; GDSC2	1.3241	3.5223	-0.8185	2.3694
NCC-IT	GDSC2	1.6446	3.8739	-0.7989	1.8367
KGN	GDSC1; GDSC2	1.6675	10.7756	-4.0691	18.862
UWB1.289	GDSC1; GDSC2	2.7682	5.5204	-0.9351	1.3079

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