Details of the Drug

General Information of Drug (ID: DMQ52JG)

Drug Name
Phenformin
Synonyms
Azucaps; Cronoformin; DBI; Debeone; Debinyl; Diabis; Dibein; Dibiraf; Dibotin; Dipar; Feguanide; Fenfoduron; Fenformin; Fenformina; Fenormin; Glukopostin; Glyphen; Insoral; Lentobetic; Meltrol; Normoglucina; Pedg; Phenethyldiguanide; Phenformine; Phenforminum; Phenformix; Phenylethylbiguanide; Retardo; D Bretard; DB Comb; DBI monohydrochloride; Phenformine HCl; Phenoformine hydrochloride; W 32; Beta-PEBG; Beta-Phenethybiguanide; Beta-Phenethylbiguanide; Db-retard; Debeone (TN); Fenformina [INN-Spanish]; Meltrol-50; N-Phenethylbiguanide hydrochloride; Phenformin (BAN); Phenformin [INN:BAN]; Phenformine [INN-French]; Phenforminum [INN-Latin]; N'-beta-Fenetilformamidiniliminourea; N'-beta-Fenetilformamidiniliminourea [Italian]; N'-beta-Phenethylformamidinylliminourea; N-(2-Phenylethyl)imidodicarbonimidic diamide; PHENFORMIN (SEE ALSO PHENFORMIN HYDROCHLORIDE 834-28-6); 1-(diaminomethylidene)-2-phenethylguanidine; 1-Phenethylbiguanide
Indication
Disease Entry ICD 11 Status REF
Diabetic complication 5A2Y Withdrawn from market [1]
Therapeutic Class
Hypoglycemic Agents
Affected Organisms
Humans and other mammals
ATC Code
A10BA01: Phenformin
A10BA: Biguanides
A10B: BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
A10: DRUGS USED IN DIABETES
A: ALIMENTARY TRACT AND METABOLISM
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski): 0 Molecular Weight (mw) 205.26
Logarithm of the Partition Coefficient (xlogp) -0.8
Rotatable Bond Count (rotbonds) 4
Hydrogen Bond Donor Count (hbonddonor) 3
Hydrogen Bond Acceptor Count (hbondacc) 1
ADMET Property
BDDCS Class
Biopharmaceutics Drug Disposition Classification System (BDDCS) Class 3: high solubility and low permeability [2]
Bioavailability
55% of drug becomes completely available to its intended biological destination(s) [3]
MRTD
The Maximum Recommended Therapeutic Dose (MRTD) of drug that ensured maximising efficacy and moderate side effect is 8.13584 micromolar/kg/day [4]
Chemical Identifiers
Formula
C10H15N5
IUPAC Name
1-(diaminomethylidene)-2-(2-phenylethyl)guanidine
Canonical SMILES
C1=CC=C(C=C1)CCN=C(N)N=C(N)N
InChI
InChI=1S/C10H15N5/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H6,11,12,13,14,15)
InChIKey
ICFJFFQQTFMIBG-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
8249
ChEBI ID
CHEBI:8064
CAS Number
114-86-3
UNII
DD5K7529CE
DrugBank ID
DB00914
TTD ID
D07XPE
VARIDT ID
DR00561
INTEDE ID
DR1273
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
AMP-activated protein kinase (AMPK) TTLAFZV AAPK1_HUMAN ; AAKB1_HUMAN ; AAKG1_HUMAN Activator [5]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Organic cation transporter 1 (SLC22A1) DTT79CX S22A1_HUMAN Substrate [6]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 2D6 (CYP2D6)
Main DME 		DECB0K3 CP2D6_HUMAN Substrate [7]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Antithrombin-III (SERPINC1) OTDFATG0 ANT3_HUMAN Gene/Protein Processing [8]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [9]
Hypoxia-inducible factor 1-alpha (HIF1A) OTADSC03 HIF1A_HUMAN Gene/Protein Processing [10]
NAD-dependent protein deacetylase sirtuin-1 (SIRT1) OTAYZMOY SIR1_HUMAN Gene/Protein Processing [10]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC1 11.0942 13.5262 10.378 16.0607
HuO9 GDSC1 0.7501 19.6129 -2.9654 69.5598
CHSA0108 GDSC1 4.2882 8.0653 4.2491 83.242
EW-7 GDSC1 6.815 13.968 5.694 57.814
ES7 GDSC1 7.0769 10.1056 6.9997 59.8856
ES1 GDSC1 7.5834 9.6732 7.5646 54.6361
ES5 GDSC1 7.704 10.8366 7.5673 52.8971
SK-ES-1 GDSC1 8.2716 10.556 8.2137 46.3395
U2OS GDSC1 8.5789 15.2067 7.067 45.5621
EW-11 GDSC1 8.6577 10.4585 8.6292 41.4973
TC-71 GDSC1 9.4067 13.1839 8.7663 35.4732
EW-18 GDSC1 9.4203 10.9476 9.3854 32.0359
EW-3 GDSC1 9.4989 11.2271 9.4334 31.2456
ES6 GDSC1 9.8719 15.6469 8.1826 35.0984
EW-24 GDSC1 9.9433 34.7596 -1.1575 45.6786
ES8 GDSC1 9.9566 15.7187 8.2329 34.4486
EW-1 GDSC1 9.99 12.4728 9.6525 26.8949
EW-13 GDSC1 10.0039 17.1939 7.579 36.4251
NOS-1 [Human HNSCC] GDSC1 10.1028 13.8784 9.2151 28.9487
EW-16 GDSC1 10.9394 13.2762 10.337 17.102
CHSA0011 GDSC1 10.9941 15.6257 9.2741 24.1078
ES4 GDSC1 11.1311 16.8039 8.8202 26.0551
SK-PN-DW GDSC1 11.3146 15.1263 9.8147 19.1688
G-292 clone A141B1 GDSC1 11.3534 15.2901 9.7692 19.3171
CAL-78 GDSC1 11.3825 16.2349 9.3276 22.0758
SJSA-1 GDSC1 11.3952 16.9432 8.987 24.0219
MG-63 GDSC1 11.4632 11.9085 11.4318 6.4858
HuO-3N1 GDSC1 11.4984 12.306 11.3348 6.9774
CAL-72 GDSC1 11.534 12.5165 11.2809 7.1999
CHSA8926 GDSC1 12.7632 16.743 10.2048 11.0783
CADO-ES1 GDSC1 13.4026 15.0627 11.3877 1.3141
HOS GDSC1 13.4351 14.7129 11.5399 0.5591
A-673 GDSC1 13.6888 21.3579 8.6168 18.177
H-EMC-SS GDSC1 13.8589 17.3433 10.6428 5.2092
MHH-ES-1 GDSC1 14.1996 23.8256 7.7788 20.7018
SaOS-2 GDSC1 14.7992 21.6629 9.2262 12.0428
NY GDSC1 14.9504 27.8067 6.3739 23.9836
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 144 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JM1 GDSC1 13.1894 20.1739 8.8315 18.501
SU-DHL-5 GDSC1 -0.197 2.7563 -0.1973 99.2595
EoL-1 GDSC1 -0.055 3.8739 -0.0593 97.7842
YT GDSC1 1.3085 7.1097 1.2168 90.2964
MV4-11 GDSC1 3.2729 10.0585 2.9233 79.5769
L-363 GDSC1 4.4232 7.2427 4.416 85.8145
SU-DHL-8 GDSC1 4.4312 5.3212 4.4312 92.7881
ALL-PO GDSC1 4.5636 8.1305 4.53 82.0673
697 GDSC1 5.002 7.4081 4.9982 82.5813
SU-DHL-4 GDSC1 5.0745 7.765 5.0658 80.9983
Karpas-620 GDSC1 5.2555 9.975 5.0744 73.2922
Karpas-45 GDSC1 5.6063 9.7248 5.4844 72.1054
MHH-PREB-1 GDSC1 5.6126 8.2296 5.6012 76.1533
SUP-B15 GDSC1 5.6652 12.8933 4.8158 65.1696
GR-ST GDSC1 5.7264 10.2849 5.5309 70.004
ST486 GDSC1 5.742 8.7761 5.7119 73.7755
P30/OHK GDSC1 5.7574 8.74 5.7296 73.7614
NALM-6 GDSC1 5.7785 8.3561 5.7665 74.5811
Ku812 GDSC1 6.1601 7.197 6.1601 72.5151
MOLT-16 GDSC1 6.4209 8.8872 6.405 67.9184
U-698-M GDSC1 6.4277 15.1116 4.8448 58.8882
ATN-1 GDSC1 6.4484 11.6794 6.0202 62.7783
OCI-M1 GDSC1 6.4801 10.0729 6.3697 65.2939
SU-DHL-6 GDSC1 6.5038 9.8641 6.4201 65.4761
DB GDSC1 6.5186 9.2633 6.4871 66.3859
RPMI-8866 GDSC1 6.537 10.4604 6.3739 64.1559
ML-2 GDSC1 6.5631 9.0467 6.5443 66.299
MOLP-8 GDSC1 6.6638 10.3713 6.524 63.2838
P12-Ichikawa GDSC1 6.7805 10.3366 6.6541 62.3472
MC116 GDSC1 6.7981 8.7626 6.7926 64.1702
Namalwa GDSC1 6.8071 7.9744 6.807 64.4525
WIL2 NS GDSC1 6.8385 10.5921 6.6765 61.4834
Reh GDSC1 6.8397 9.6033 6.7977 62.8173
OCI-AML-2 GDSC1 6.9617 9.1961 6.947 61.992
LC4-1 GDSC1 6.9874 11.0761 6.7472 59.5936
OCI-Ly19 GDSC1 7.026 8.4015 7.0255 61.692
ALL-SIL GDSC1 7.0566 10.2987 6.9543 59.8737
KG-1 GDSC1 7.0571 11.49 6.7309 58.547
RPMI-8402 GDSC1 7.1175 11.1986 6.8627 58.3437
GDM-1 GDSC1 7.1828 9.9396 7.1285 58.967
HH [Human lymphoma] GDSC1 7.28 11.6251 6.9409 56.542
KOPN-8 GDSC1 7.2915 9.0424 7.287 58.3048
A3/Kawakami GDSC1 7.3073 8.3618 7.3072 58.2261
SU-DHL-10 GDSC1 7.3663 8.1487 7.3663 57.4935
NU-DUL-1 GDSC1 7.3712 8.6633 7.3708 57.4125
CTV-1 GDSC1 7.4287 9.3996 7.4174 56.5506
HL-60 GDSC1 7.5268 9.8664 7.4944 55.2298
Ramos.2G6.4C10 GDSC1 7.5681 8.9526 7.5669 54.953
RS4;11 GDSC1 7.5906 10.4817 7.4992 54.2565
CESS GDSC1 7.5925 8.839 7.5919 54.6579
K-562 GDSC1 7.6558 12.7711 7.0199 52.6944
Raji GDSC1 7.7461 8.7739 7.746 52.7451
HAL-01 GDSC1 7.7538 11.1816 7.557 52.2704
LP-1 GDSC1 7.809 11.3477 7.582 51.6571
SU-DHL-16 GDSC1 7.8459 8.5853 7.8459 51.4989
BALL-1 GDSC1 7.9531 9.5161 7.9481 50.1574
NKM-1 GDSC1 7.9577 9.8736 7.9403 50.0987
SR GDSC1 7.9595 10.7842 7.8503 50.0721
CA46 GDSC1 7.9644 10.0391 7.9375 50.0166
Mono-Mac-6 GDSC1 7.9831 11.9904 7.6127 49.8266
KE-37 GDSC1 8.0032 9.5385 7.9984 49.5359
SIG-M5 GDSC1 8.0353 10.3044 7.9903 49.1671
Daudi GDSC1 8.0496 9.3477 8.048 48.9547
MEG-01 GDSC1 8.0686 13.971 7.0359 49.1883
AMO1 GDSC1 8.0732 11.4376 7.8494 48.8407
NOMO-1 GDSC1 8.0851 10.2245 8.0496 48.5564
HT GDSC1 8.1295 9.5615 8.1259 47.9619
CCRF-CEM GDSC1 8.1326 9.7127 8.1256 47.9314
HC-1 GDSC1 8.1354 9.2722 8.1348 47.8812
SK-MM-2 GDSC1 8.1566 12.3739 7.6905 48.143
VL51 GDSC1 8.2016 12.3851 7.7361 47.6963
BE-13 GDSC1 8.202 14.2508 7.0682 48.1671
PF-382 GDSC1 8.2196 10.6582 8.1462 46.9966
Sc-1 GDSC1 8.3422 12.7398 7.7757 46.4227
CTB-1 GDSC1 8.4072 11.4241 8.2156 45.0586
SU-DHL-1 GDSC1 8.4106 14.9908 6.984 46.7596
THP-1 GDSC1 8.4756 10.6706 8.4166 43.8655
SUP-T1 GDSC1 8.4944 11.2842 8.3393 43.9494
MLMA GDSC1 8.5078 10.2903 8.4853 43.329
EJM GDSC1 8.5379 12.508 8.0639 44.2746
LAMA-84 GDSC1 8.5461 15.1047 7.0766 45.7655
RL GDSC1 8.5657 12.0209 8.24 43.6144
Loucy GDSC1 8.568 9.3974 8.5679 42.473
Jiyoye GDSC1 8.5765 11.2976 8.4257 42.9677
ROS-50 GDSC1 8.6371 14.2419 7.5318 44.5211
VAL GDSC1 8.7331 10.6117 8.695 40.6092
MOLM-13 GDSC1 8.7384 13.548 7.9132 43.0534
TK [Human B-cell lymphoma] GDSC1 8.8001 10.038 8.796 39.5953
BC-1 GDSC1 8.8625 15.3812 7.2835 43.4455
TUR GDSC1 8.8653 17.3218 6.4079 44.6504
KMOE-2 GDSC1 8.9084 12.15 8.5771 39.7686
MOLT-4 GDSC1 8.921 10.0994 8.9173 38.082
PL-21 GDSC1 9.0006 12.5941 8.5387 39.2347
EB2 GDSC1 9.0499 10.4573 9.0365 36.5296
BL-41 GDSC1 9.0788 10.7344 9.0468 36.2785
SUP-M2 GDSC1 9.1743 12.1907 8.8551 36.6221
NB4 GDSC1 9.187 11.5278 9.0406 35.5825
RPMI-8226 GDSC1 9.1899 11.6238 9.0224 35.6617
JSC-1 GDSC1 9.1991 11.6226 9.0328 35.5429
KMS-12-BM GDSC1 9.2103 12.588 8.7684 36.7797
OCI-AML-5 GDSC1 9.224 10.4213 9.2169 34.3165
MN-60 GDSC1 9.5005 15.0778 8.0695 37.607
DEL GDSC1 9.5146 15.9438 7.6902 38.6758
QIMR-WIL GDSC1 9.5706 12.7238 9.1116 32.6791
HEL GDSC1 9.5711 13.6108 8.7729 34.3951
DG-75 GDSC1 9.5784 11.1564 9.5285 30.1559
DND-41 GDSC1 9.6036 11.5261 9.4933 30.2211
OCI-AML-3 GDSC1 9.662 14.4316 8.5204 34.9609
RC-K8 GDSC1 9.751 11.7372 9.6071 28.6013
Hs 445 GDSC1 9.8203 11.5354 9.7263 27.4186
L-1236 GDSC1 9.8296 12.5752 9.4437 29.1573
KCL-22 GDSC1 10.1145 15.5723 8.4566 32.6924
Granta-519 GDSC1 10.1338 12.9354 9.6379 26.1729
WSU-NHL GDSC1 10.2435 24.3423 4.2895 41.4837
MY-M12 GDSC1 10.4 21.3562 5.9094 38.6039
ARH-77 GDSC1 10.6485 11.9446 10.534 17.2164
BC-3 GDSC1 10.6628 20.8256 6.408 36.5845
HDLM-2 GDSC1 10.7588 14.4442 9.6182 23.0428
JVM-3 GDSC1 10.9876 15.1496 9.4998 22.7326
SUP-HD1 GDSC1 11.0214 14.7004 9.7492 20.9238
Karpas-299 GDSC1 11.0768 16.259 9.0397 25.1002
RPMI-6666 GDSC1 11.0915 12.1906 10.942 11.9321
U266B1 GDSC1 11.2093 16.1146 9.2315 23.4025
JJN-3 GDSC1 11.221 15.6057 9.4931 21.7284
OPM-2 GDSC1 11.2315 12.7401 10.8727 11.7108
A4/Fukuda GDSC1 11.2783 12.1229 11.1674 9.3365
JVM-2 GDSC1 11.3674 17.3367 8.7667 25.3273
ME1 GDSC1 11.4211 11.8895 11.3903 7.0079
Farage GDSC1 11.4671 12.0193 11.4061 6.6379
SCC-3 GDSC1 11.49 11.8659 11.47 6.0764
EM-2 GDSC1 11.5965 21.5443 6.8654 31.9588
WSU-DLCL2 GDSC1 11.8829 28.6093 3.5748 37.6772
JURL-MK1 GDSC1 12.0264 19.7473 8.1254 25.8476
P32/ISH GDSC1 12.0616 13.0299 11.5113 3.2518
Karpas-422 GDSC1 12.2865 19.1832 8.6207 22.5666
MOLT-13 GDSC1 12.7298 15.2944 10.8871 6.0979
KY821 GDSC1 12.9957 30.8664 3.3594 35.2832
L-540 GDSC1 13.4668 14.8301 11.5087 0.6613
H9 GDSC1 13.6569 16.1777 11.0462 2.9537
P31/FUJ GDSC1 13.7434 31.2166 3.7788 32.9116
KM-H2 GDSC1 13.8295 15.3042 11.48 0.5064
L-428 GDSC1 13.9377 15.4808 11.4581 0.5143
BV-173 GDSC1 13.9807 25.4942 6.7985 24.977
KMS-11 GDSC1 14.2033 15.7981 11.4462 0.4066
⏷ Show the Full List of 144 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-50 GDSC1 10.0175 12.6017 9.6373 26.8358
KYSE-220 GDSC1 11.9273 23.8221 6.0055 33.15
OACP4 C GDSC1 11.9359 13.5883 11.1294 6.7048
SK-GT-4 GDSC1 12.6454 14.6337 11.1469 4.3711
FLO-1 GDSC1 13.0251 17.0408 10.2478 10
TE-12 GDSC1 13.078 22.7588 7.4658 25.1048
ESO-26 GDSC1 13.2849 14.9297 11.3853 1.4823
KYAE-1 GDSC1 13.4375 16.0067 11 3.6497
OACM5.1 C GDSC1 13.4969 16.2122 10.942 3.9228
ESO-51 GDSC1 13.8158 15.6374 11.3478 1.0569
HCE-4 GDSC1 15.0907 24.3984 8.1213 16.9967
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC1 8.4667 13.7446 7.5477 45.7391
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CHP-212 GDSC1 9.0464 11.444 8.9056 37.2713
GI-ME-N GDSC1 9.1168 17.0511 6.7827 42.8025
SK-N-AS GDSC1 9.8344 11.1004 9.8066 26.818
NB1 GDSC1 10.7884 13.0573 10.2778 18.2816
SJNB-12 GDSC1 11.2777 15.5487 9.5729 20.9624
SK-N-SH GDSC1 11.4165 12.0167 11.3517 7.2948
SJNB-7 GDSC1 11.5945 14.2372 10.5076 12.8931
NB69 GDSC1 11.6284 21.8108 6.7594 32.1553
SK-N-MC-IXC GDSC1 12.2034 15.1506 10.5668 10.166
SK-N-BE(2)-M17 GDSC1 12.2843 17.0899 9.6641 16.4286
SJNB-10 GDSC1 12.5376 15.3571 10.7199 7.9187
MHH-NB-11 GDSC1 12.6635 16.8099 10.0977 12.1572
SJNB-13 GDSC1 12.6941 14.4738 11.2543 3.4563
CHP-126 GDSC1 12.7019 14.1835 11.3938 2.4393
SK-N-FI GDSC1 12.8194 16.9684 10.1353 11.4079
SK-N-DZ GDSC1 12.8595 22.535 7.4062 25.9924
SJNB-6 GDSC1 12.8913 14.6818 11.2796 2.8367
SJNB-14 GDSC1 12.9474 14.5534 11.3695 2.1193
Kelly GDSC1 13.2885 14.9 11.3994 1.3978
IMR-5 GDSC1 13.4045 15.0376 11.3988 1.2524
TGW GDSC1 13.4075 14.9617 11.4309 1.0827
SJNB-17 GDSC1 13.5275 15.5361 11.2529 1.9024
SiMa GDSC1 13.53 15.4515 11.2894 1.6897
CHP-134 GDSC1 13.6331 14.8035 11.5851 0.2848
LA-N-6 GDSC1 13.637 22.8716 7.8353 21.9871
KP-N-YN GDSC1 13.6659 15.321 11.4052 0.9374
NH-12 GDSC1 13.7817 15.3298 11.4512 0.6448
GOTO GDSC1 13.8515 18.4661 10.1206 8.7364
SJNB-5 GDSC1 13.8691 15.3378 11.4834 0.471
NB(TU)1 GDSC1 13.9064 15.3931 11.4778 0.4674
KP-N-YS GDSC1 14.0986 16.3504 11.1934 1.5058
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC1 11.3955 12.259 11.2445 8.1621
Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC2218 GDSC1 -0.3992 9.3232 -0.9098 85.7538
HCC1500 GDSC1 0.2425 267.689 -125.792 51.5856
OCUB-M GDSC1 3.9144 15.2283 2.1134 67.942
DU4475 GDSC1 4.1144 10.0494 3.8341 77.4518
HCC202 GDSC1 5.1715 46.5193 -11.2553 53.6916
MDA-MB-468 GDSC1 5.644 10.8845 5.3289 69.0722
MDA-MB-453 GDSC1 5.741 12.4453 5.0358 65.5382
HCC2157 GDSC1 6.3345 18.3444 3.3897 57.099
MCF-7 GDSC1 6.5815 13.0133 5.7736 60.149
BT-474 GDSC1 8.3608 23.5946 2.9287 48.6142
HCC1599 GDSC1 8.3686 13.8719 7.394 46.6648
CAL-148 GDSC1 8.5205 14.2527 7.4043 45.5378
MRK-nu-1 GDSC1 8.5884 13.9162 7.6105 44.7413
CAMA-1 GDSC1 8.9693 14.2077 7.8953 41.4716
HCC1806 GDSC1 9.4152 11.1287 9.3581 32.237
ZR-75-30 GDSC1 9.5726 13.4184 8.8517 34.0096
MDA-MB-231 GDSC1 9.6046 12.2585 9.3034 31.3734
BT-549 GDSC1 9.8466 12.7597 9.3963 29.3464
MDA-MB-415 GDSC1 9.8831 28.2863 2.0109 44.4066
HCC38 GDSC1 9.9873 12.0339 9.7876 26.0279
Hs 578T GDSC1 10.0445 11.4749 9.9798 24.43
Evsa-T GDSC1 10.1332 17.2829 7.6594 35.5449
HCC1954 GDSC1 10.3438 18.1319 7.4449 35.2165
UACC-893 GDSC1 10.4289 21.305 5.9608 38.399
AU565 GDSC1 10.7323 15.068 9.2963 25.2051
MDA-MB-157 GDSC1 10.9466 12.9949 10.4684 16.1016
HCC1395 GDSC1 10.9922 17.726 8.2389 29.4335
COLO 824 GDSC1 11.1109 18.0393 8.1902 29.1345
HCC70 GDSC1 11.2769 15.0781 9.8038 19.4075
HCC1569 GDSC1 11.29 16.0156 9.3533 22.3114
HDQ-P1 GDSC1 11.2909 14.846 9.9307 18.4561
BT-20 GDSC1 11.3126 19.7283 7.5276 30.8806
T-47D GDSC1 11.3414 13.5637 10.6013 13.2496
HCC1937 GDSC1 11.3637 12.7252 11.0146 10.0114
CAL-120 GDSC1 11.3652 12.8269 10.9702 10.3376
MFM-223 GDSC1 11.3734 12.8916 10.9488 10.4599
MDA-MB-436 GDSC1 11.4787 12.1885 11.3603 6.8958
MDA-MB-330 GDSC1 11.481 20.995 7.0411 31.843
EFM-19 GDSC1 11.4858 12.375 11.2929 7.3477
EFM-192A GDSC1 11.5166 13.2272 10.9304 9.9521
HCC1419 GDSC1 11.5664 21.4922 6.8658 32.0635
UACC-812 GDSC1 11.8744 13.4139 11.1642 6.6605
MDA-MB-361 GDSC1 12.1832 15.5554 10.3488 11.8964
YMB-1-E GDSC1 12.1987 23.8529 6.2151 31.7807
CAL-85-1 GDSC1 12.9424 17.1018 10.1592 10.8712
HCC1187 GDSC1 12.9835 25.5057 6.0241 29.9877
CAL-51 GDSC1 13.2395 22.1795 7.8777 22.9566
JIMT-1 GDSC1 13.2724 21.0895 8.4418 20.267
MDA-MB-175-VII GDSC1 13.4512 32.3103 3.0034 34.7935
BT-483 GDSC1 13.6097 14.9172 11.5348 0.4554
HCC1428 GDSC1 16.0794 24.4726 8.7172 12.0356
⏷ Show the Full List of 51 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
D-247MG GDSC1 6.2842 9.9358 6.1787 67.0901
GB-1 GDSC1 6.5162 9.883 6.4311 65.3386
KINGS-1 GDSC1 7.9059 10.7656 7.7957 50.6826
KNS-81-FD GDSC1 7.9273 12.3206 7.4567 50.3668
KALS-1 GDSC1 8.2241 12.1096 7.8422 47.3816
ONS-76 GDSC1 8.2787 13.1155 7.5783 47.1843
GI-1 GDSC1 8.5327 10.8762 8.4506 43.2536
A-172 GDSC1 8.6126 10.7577 8.5516 42.1977
MOG-G-CCM GDSC1 8.7039 16.5263 6.6112 45.3135
U-251MG GDSC1 8.9676 16.2104 7.0202 43.2516
SNB-75 GDSC1 9.0525 14.2024 7.9848 40.676
DBTRG-05MG GDSC1 9.3763 12.447 8.9951 34.5525
LN-405 GDSC1 9.838 11.5251 9.7475 27.175
8-MG-BA GDSC1 9.8784 13.7088 9.0548 31.1212
D-336MG GDSC1 9.8904 12.5956 9.5022 28.4345
SW1783 GDSC1 10.0384 11.7697 9.9124 24.9067
SF539 GDSC1 10.3185 14.5551 9.1311 28.2598
YKG-1 GDSC1 10.4083 14.7653 9.1232 27.8352
LNZTA3WT4 GDSC1 10.4161 12.8061 9.9888 22.2664
D-542MG GDSC1 10.4626 15.73 8.7203 29.685
Daoy GDSC1 10.5577 13.6613 9.7769 22.9818
KNS-42 GDSC1 10.5581 11.8166 10.4675 18.1847
NMC-G1 GDSC1 10.5604 14.4047 9.4413 25.163
D-423MG GDSC1 10.5825 16.7307 8.351 30.8059
Becker GDSC1 10.6147 13.2394 10.0198 21.0081
DK-MG GDSC1 10.7213 12.7535 10.3335 18.2239
Onda 11 GDSC1 10.7473 15.5226 9.0922 26.3257
PFSK-1 GDSC1 10.8385 28.8665 2.5586 41.4979
D-392MG GDSC1 10.8719 13.7046 10.0745 19.3397
LN-18 GDSC1 10.9723 11.8014 10.9217 12.7455
M059J GDSC1 11.0529 14.4095 9.9193 19.5977
MOG-G-UVW GDSC1 11.0922 15.3822 9.4843 22.3564
D-263MG GDSC1 11.1324 16.6545 8.8952 25.6499
Onda 10 GDSC1 11.1714 15.887 9.3093 23.0987
CAS-1 GDSC1 11.1738 13.1368 10.6368 13.7497
KS-1 [Human Krukenberg tumour] GDSC1 11.2654 13.3276 10.6394 13.3032
D283 Med GDSC1 11.2869 12.2359 11.1369 9.5046
H4 GDSC1 11.3269 12.748 10.9669 10.5455
SF126 GDSC1 11.3361 21.6725 6.5781 33.6797
U-87MG ATCC GDSC1 11.3406 11.8264 11.3158 7.9741
T98G GDSC1 11.341 14.6551 10.0706 17.233
SF295 GDSC1 11.3453 11.9352 11.2967 8.0734
U-118MG GDSC1 11.3632 12.0185 11.293 7.9967
Hs 683 GDSC1 11.389 11.8284 11.3678 7.3453
D-502MG GDSC1 11.436 12.2104 11.3063 7.5076
SW1088 GDSC1 11.4471 13.0519 10.947 10.1334
LN-229 GDSC1 11.4774 17.1666 8.948 23.8984
42-MG-BA GDSC1 11.4804 12.0026 11.4256 6.43
D-566MG GDSC1 12.3839 17.5462 9.5159 17.0547
GaMG GDSC1 12.5 18.9612 8.9027 20.3268
YH-13 GDSC1 13.0744 15.0899 11.2023 2.9959
AM-38 GDSC1 13.3637 16.4657 10.7467 5.5521
SF268 GDSC1 13.6004 17.499 10.4138 7.3345
SK-MG-1 GDSC1 14.4213 24.2921 7.7099 20.421
⏷ Show the Full List of 54 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC24TKB GDSC1 10.0875 14.6727 8.8458 31.025
ETK-1 GDSC1 11.3176 16.2074 9.2832 22.6232
TGBC1TKB GDSC1 13.24 15.7821 10.9859 4.146
Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KLE GDSC1 10.3377 15.5175 8.7007 30.4123
MFE-280 GDSC1 10.6806 19.7422 6.9606 35.1495
RL95-2 GDSC1 11.2623 12.3928 11.0504 10.2532
EN GDSC1 11.9605 19.8832 8.0027 26.6148
MFE-319 GDSC1 12.1749 13.1868 11.5196 2.8307
MFE-296 GDSC1 12.987 16.9243 10.2774 9.8952
AN3-CA GDSC1 13.1722 15.9266 10.8777 5.0597
ESS-1 GDSC1 13.3125 14.7305 11.4796 0.9434
⏷ Show the Full List of 8 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
786-O GDSC1 10.014 18.8183 6.8025 38.3852
BB65-RCC GDSC1 10.1654 13.7747 9.3246 27.9589
OS-RC-2 GDSC1 10.1772 13.9048 9.2801 28.1592
UO-31 GDSC1 11.101 12.7675 10.726 13.4398
LB1047-RCC GDSC1 11.3158 18.3616 8.2113 28.1929
KTCTL-21 GDSC1 11.3352 15.1135 9.8398 18.9056
SW13 GDSC1 11.4271 12.1591 11.3157 7.4874
CAL-54 GDSC1 11.4581 12.4593 11.2281 7.9628
VMRC-RCZ GDSC1 11.4919 17.2165 8.9357 23.9068
BFTC-909 GDSC1 11.6367 12.8601 11.2216 7.1807
VMRC-RCW GDSC1 11.6749 12.7574 11.3075 6.3512
SW156 GDSC1 11.7913 13.5205 11.0386 7.9695
KTCTL-140 GDSC1 11.9957 13.761 11.093 6.7757
769-P GDSC1 12.4327 21.5689 7.5476 26.8143
SN12C GDSC1 12.5834 19.3548 8.7725 20.7527
KTCTL-26A GDSC1 12.5923 14.4306 11.2082 4.0499
RXF 393L GDSC1 12.732 17.1941 9.9594 12.9195
RCC10RGB GDSC1 12.996 17.0965 10.2001 10.424
A-498 GDSC1 13.0571 18.465 9.5748 14.498
KTCTL-195 GDSC1 13.0702 15.5808 10.9748 4.5994
LB996-RCC GDSC1 13.083 15.4279 11.0535 4.0112
NCC021 GDSC1 13.1358 14.8592 11.3385 1.9898
KTCTL-13 GDSC1 13.3644 17.3255 10.3427 8.411
KTCTL-1M GDSC1 13.4748 15.381 11.2915 1.7542
TK-10 GDSC1 13.7809 15.819 11.2595 1.5324
LB2241-RCC GDSC1 13.847 26.5344 6.1837 27.2403
Caki-1 GDSC1 14.4474 25.5285 7.1249 22.6427
HA7-RCC GDSC1 14.5668 16.1703 11.4497 0.2547
ACHN GDSC1 14.7603 25.0296 7.5908 20.0707
KMRC-20 GDSC1 14.9636 22.3367 9.0151 12.8371
KMRC-1 GDSC1 15.3234 25.4633 7.7686 18.0112
⏷ Show the Full List of 31 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 44 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SW1463 GDSC1 0.1512 745.1132 -364.4994 50.5762
LoVo GDSC1 1.2443 22.6662 -3.7318 66.3796
CW-2 GDSC1 5.0409 13.7827 3.8444 66.3944
SNU-C1 GDSC1 5.1449 11.9565 4.5245 69.1448
CCK-81 GDSC1 6.5795 10.6007 6.3961 63.5873
LS411N GDSC1 6.7815 9.8879 6.711 62.9887
HT-55 GDSC1 6.9905 21.7536 2.4904 53.5195
SNU-C2B GDSC1 7.5792 11.6797 7.2536 53.8125
KM12 GDSC1 7.8687 10.2271 7.8225 51.1565
LS513 GDSC1 8.2624 10.9197 8.1542 46.5564
SW948 GDSC1 8.3113 13.6495 7.418 47.0794
HT115 GDSC1 8.7671 20.2989 4.905 46.364
SW837 GDSC1 8.7982 11.609 8.5993 40.5243
NCI-H747 GDSC1 9.1952 14.0358 8.2033 39.0716
RKO GDSC1 9.278 11.7916 9.0782 34.763
COLO 320HSR GDSC1 9.5612 14.4676 8.401 36.0501
GP5d GDSC1 9.7918 11.8491 9.6241 28.2464
NCI-H716 GDSC1 9.8872 11.5745 9.7909 26.5989
RCM-1 [Human ESC] GDSC1 10.0703 42.4206 -4.8686 46.4542
C2BBe1 GDSC1 10.0861 12.4059 9.7793 25.5122
HCT 15 GDSC1 10.2435 14.4095 9.1223 28.7082
T84 GDSC1 10.807 13.2297 10.2224 18.5895
SW626 GDSC1 10.8523 13.6346 10.087 19.3451
SNU-175 GDSC1 10.8626 22.3356 5.8351 37.0584
COLO205 GDSC1 11.0648 14.6101 9.834 20.1416
LS123 GDSC1 11.119 12.0511 11.0171 11.2599
LS1034 GDSC1 11.2392 16.2691 9.1822 23.5654
HT-29 GDSC1 11.2762 19.149 7.7845 30.0882
HCT 116 GDSC1 11.336 18.0454 8.3864 27.3243
CaR-1 GDSC1 11.4203 12.255 11.2725 7.8318
SW48 GDSC1 11.47 21.0169 7.0207 31.9456
HCC2998 GDSC1 12.0845 26.6645 4.7151 35.3638
COLO 678 GDSC1 12.1265 13.5166 11.3199 4.5404
MDST8 GDSC1 12.5046 15.7895 10.4823 9.826
SW1417 GDSC1 12.8552 26.1973 5.577 31.4619
SNU-1040 GDSC1 13.0413 16.5365 10.5027 8.1099
SNU-61 GDSC1 13.3643 15.3148 11.263 2.0869
CL-11 GDSC1 13.6042 18.9342 9.7344 11.9097
SW1116 GDSC1 13.6502 15.1257 11.4735 0.6571
SNU-407 GDSC1 13.6737 20.6805 8.9368 16.5131
SNU-81 GDSC1 14.3116 27.7059 5.9549 26.7395
SNU-C5 GDSC1 14.4523 23.8291 7.9569 19.2827
SW620 GDSC1 15.2294 25.899 7.4957 19.3482
LS180 GDSC1 15.4801 26.8299 7.2194 19.8569
⏷ Show the Full List of 44 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC1 8.7217 13.341 7.9735 43.0384
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JHH-4 GDSC1 8.6625 32.533 -1.1856 48.4151
Huh-7 GDSC1 10.8135 11.8067 10.7478 14.8288
SNU-387 GDSC1 11.2959 13.4454 10.6137 13.3591
Hep 3B2.1-7 GDSC1 11.4269 14.5065 10.2225 15.748
HuH-1 GDSC1 11.8566 14.3877 10.6627 10.6645
SNU-423 GDSC1 12.3831 19.8849 8.3484 23.5724
JHH-7 GDSC1 12.4425 14.8685 10.89 6.9001
JHH-6 GDSC1 12.5364 14.7056 11.0374 5.4939
JHH-1 GDSC1 12.5878 14.0457 11.3872 2.7412
SNU-449 GDSC1 12.9561 21.8725 7.8116 24.0944
JHH-2 GDSC1 13.2178 17.0343 10.3837 8.4998
HLE GDSC1 13.2838 17.5261 10.1926 9.6776
SNU-398 GDSC1 13.5414 19.1091 9.6067 12.8988
SNU-475 GDSC1 13.6291 14.8442 11.569 0.3334
Hep-G2/C3A GDSC1 14.3409 25.9014 6.8647 23.8328
SK-HEP-1 GDSC1 15.7358 24.5061 8.4898 13.8416
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 171 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H292 GDSC1 5.3441 9.1943 5.2658 75.0458
NCI-H841 GDSC1 5.4755 9.2237 5.4012 74.2306
NCI-H661 GDSC1 6.2344 11.436 5.8473 64.5536
COR-L95 GDSC1 6.4937 11.6957 6.0655 62.4534
Lu-139 GDSC1 6.9735 27.3639 -0.207 52.6301
NCI-H2029 GDSC1 7.1051 20.2176 3.3197 53.4709
EPLC-272H GDSC1 7.1095 10.4758 6.9859 59.1769
NCI-H2196 GDSC1 7.1283 15.2781 5.5201 55.138
NCI-H1944 GDSC1 7.3748 11.2894 7.1227 55.9531
NCI-H1755 GDSC1 7.4597 11.3397 7.2038 55.1245
DMS 53 GDSC1 7.5567 110.4823 -41.0133 50.2182
Calu-6 GDSC1 7.6213 11.4118 7.3635 53.5306
NCI-H1770 GDSC1 7.6919 22.6326 2.7553 50.9789
NCI-H2087 GDSC1 8.2008 12.2828 7.7661 47.6752
UMC-11 GDSC1 8.3096 10.6132 8.2473 45.8913
NCI-H196 GDSC1 8.4058 10.2019 8.385 44.5858
NCI-H1694 GDSC1 8.4234 12.9723 7.7848 45.7346
NCI-H82 GDSC1 8.4513 127.0933 -48.5523 49.7753
Ms-1 GDSC1 8.4864 11.4331 8.2997 44.1335
COR-L105 GDSC1 8.5192 22.1363 3.7844 47.8432
CPC-N GDSC1 8.5799 12.2844 8.179 43.6548
CAL-12T GDSC1 8.7491 11.4601 8.5794 40.9894
NCI-H187 GDSC1 8.7948 1587.7115 -778.5511 49.9712
NCI-H211 GDSC1 8.8115 18.5565 5.7771 45.5429
NCI-H1437 GDSC1 8.8225 12.52 8.3695 41.1701
DMS 273 GDSC1 8.8331 11.3429 8.6947 39.8496
LCLC-97TM1 GDSC1 8.8462 11.7273 8.6233 40.0556
HCC44 GDSC1 8.852 12.6861 8.3468 41.0202
NCI-H524 GDSC1 8.8603 12.4117 8.4452 40.6236
NCI-H1581 GDSC1 8.887 12.8495 8.3289 40.8159
A-427 GDSC1 8.9141 12.047 8.6129 39.5819
LK-2 GDSC1 8.9302 10.1166 8.9263 37.9684
NCI-H1792 GDSC1 8.9656 11.6192 8.7793 38.4734
NCI-H1299 GDSC1 8.9723 12.6608 8.4858 39.6418
NCI-H520 GDSC1 9.025 14.8593 7.6781 41.6308
NCI-H1304 GDSC1 9.0519 14.5467 7.8398 41.065
NCI-H1975 GDSC1 9.0593 12.9225 8.4892 39.0008
NCI-H522 GDSC1 9.1524 16.1118 7.2508 41.7743
NCI-H810 GDSC1 9.1617 10.3726 9.1549 35.0931
Lu-99A GDSC1 9.2264 10.7259 9.2022 34.3911
NCI-H358 GDSC1 9.2493 10.5404 9.2378 34.0273
NCI-H1734 GDSC1 9.3554 12.1955 9.0511 34.3956
NCI-H3122 GDSC1 9.3982 12.0248 9.1474 33.5868
SBC-5 GDSC1 9.4008 15.2492 7.8916 38.7546
NCI-H1836 GDSC1 9.4243 15.4275 7.8352 38.7814
NCI-H1155 GDSC1 9.4559 17.6411 6.8374 40.953
NCI-H2009 GDSC1 9.4732 13.5408 8.6977 35.3564
NCI-H1688 GDSC1 9.5451 12.6235 9.1191 32.7991
NCI-H1563 GDSC1 9.636 11.9955 9.4151 30.5055
NCI-H1651 GDSC1 9.6561 14.8847 8.314 35.822
LC-2/ad GDSC1 9.6693 14.165 8.6434 34.3852
NCI-H1963 GDSC1 9.6869 12.9759 9.1449 31.7733
NCI-H650 GDSC1 9.716 11.054 9.6864 28.3088
NCI-H1648 GDSC1 9.7208 13.5403 8.9592 32.5605
DMS 114 GDSC1 9.7261 18.1099 6.8734 39.5603
EKVX GDSC1 9.7587 13.8842 8.8559 32.8536
NCI-H2228 GDSC1 9.8548 11.7975 9.7056 27.345
PaCa-3 GDSC1 10.0745 15.8873 8.2694 33.6789
Lu-65 GDSC1 10.0868 16.0188 8.2193 33.8122
LCLC-103H GDSC1 10.1015 19.418 6.5911 38.4621
HCC33 GDSC1 10.1384 18.0136 7.3106 36.5506
COLO 668 GDSC1 10.1933 26.1208 3.3618 42.5613
NCI-H647 GDSC1 10.2544 11.2771 10.2314 21.5383
NCI-H2110 GDSC1 10.333 11.9912 10.1768 21.4344
NCI-H838 GDSC1 10.3337 11.9175 10.1976 21.2908
SW1271 GDSC1 10.4919 11.8499 10.3874 19.104
HOP-62 GDSC1 10.4931 27.2184 3.0799 41.9544
ABC-1 GDSC1 10.5113 25.2112 4.0951 40.8621
NCI-H1703 GDSC1 10.528 15.5391 8.8745 28.5792
NCI-H1869 GDSC1 10.536 14.2812 9.4742 25.0795
Lu-134-A GDSC1 10.5438 12.8149 10.1211 20.6629
COR-L23 GDSC1 10.6839 13.3121 10.0599 20.3717
NCI-H345 GDSC1 10.7161 17.3441 8.1754 30.9274
NCI-H1666 GDSC1 10.7314 12.0933 10.5818 16.4211
HCC15 GDSC1 10.8499 13.7088 10.0506 19.6182
SHP-77 GDSC1 10.8681 26.6173 3.7064 40.2549
LC-1/sq GDSC1 10.8713 13.6612 10.0939 19.2036
NCI-H513 GDSC1 10.8953 14.9253 9.5208 23.0265
NCI-H1915 GDSC1 10.91 13.8324 10.0533 19.3095
NCI-H446 GDSC1 10.9674 11.8921 10.8954 12.9488
A-549 GDSC1 10.9985 11.9882 10.904 12.7126
NCI-H2347 GDSC1 11.0098 12.7935 10.6201 14.673
NCI-H460 GDSC1 11.0915 16.0401 9.1609 24.3398
BEN GDSC1 11.1038 21.6494 6.3881 34.9895
NCI-H2030 GDSC1 11.1359 12.3841 10.9194 11.8546
NCI-H1436 GDSC1 11.1536 16.8047 8.8401 25.8518
LXF 289 GDSC1 11.1933 15.3509 9.5931 21.1989
NCI-H510A GDSC1 11.2121 16.6337 8.9774 24.8537
NCI-H1355 GDSC1 11.2367 15.7022 9.4599 21.8718
NCI-H1993 GDSC1 11.2587 18.3528 8.1655 28.6245
PC-14 GDSC1 11.2683 12.6595 10.9456 10.99
SW1573 GDSC1 11.2714 20.4923 7.1109 32.4033
NCI-H847 GDSC1 11.2846 11.9438 11.2283 8.8836
NCI-H2171 GDSC1 11.2864 12.8508 10.8798 11.3915
LOU-NH91 GDSC1 11.3009 15.5941 9.5715 20.8719
NCI-H1693 GDSC1 11.3018 13.4629 10.6112 13.3516
NCI-H720 GDSC1 11.3062 19.3429 7.7141 30.2329
ChaGo-K-1 GDSC1 11.3233 14.036 10.3563 15.1896
DMS 79 GDSC1 11.3278 18.5124 8.1467 28.4225
NCI-H2085 GDSC1 11.3348 12.3992 11.1245 9.3434
NCI-H1876 GDSC1 11.35 12.6908 11.0158 10.0683
NCI-H2170 GDSC1 11.3671 18.3444 8.2648 27.7483
NCI-H1623 GDSC1 11.3775 13.4077 10.7106 12.254
IA-LM GDSC1 11.3781 17.0917 8.898 24.5838
SK-LU-1 GDSC1 11.387 12.1658 11.2701 8.0259
NCI-H2081 GDSC1 11.3967 18.6119 8.1574 28.0994
SBC-3 GDSC1 11.4146 12.1191 11.3164 7.5502
NCI-H69 GDSC1 11.4589 12.2385 11.32 7.2884
NCI-H596 GDSC1 11.493 14.1206 10.4728 13.5786
SK-MES-1 GDSC1 11.4932 12.22 11.3637 6.795
NCI-H2122 GDSC1 11.5193 19.1989 7.9707 28.3991
NCI-H2405 GDSC1 11.58 14.8356 10.198 15.2969
NCI-H322M GDSC1 11.6678 12.5595 11.3947 5.7138
EBC-1 GDSC1 11.6753 18.6508 8.3782 26.01
NCI-H2795 GDSC1 11.7023 13.4827 10.9779 8.8001
NCI-H2023 GDSC1 11.8485 13.0264 11.3348 5.4185
Lu-165 GDSC1 11.896 17.3414 9.2196 20.6741
Calu-3 GDSC1 11.96 13.0935 11.3972 4.5054
NCI-H2141 GDSC1 12.0328 22.4891 6.7599 30.7893
NCI-H727 GDSC1 12.0651 21.2261 7.4181 28.5269
NCI-H526 GDSC1 12.1343 25.317 5.4301 33.8266
COR-L303 GDSC1 12.1734 13.6504 11.2896 4.6266
NCI-H1435 GDSC1 12.1949 27.1779 4.5498 35.3544
RERF-LC-Sq1 GDSC1 12.2407 20.4164 7.9673 25.775
COR-L88 GDSC1 12.4501 24.9848 5.8554 31.9357
RERF-LC-KJ GDSC1 12.5365 20.4983 8.1653 23.9028
NCI-H226 GDSC1 12.5518 28.5637 4.15 35.1047
NCI-H1092 GDSC1 12.6546 15.9209 10.5287 9.016
NCI-H3255 GDSC1 12.6651 17.2502 9.8813 13.6741
NCI-H1048 GDSC1 12.7138 21.4739 7.8198 24.8217
Lu-135 GDSC1 12.7375 14.5215 11.2595 3.3169
NCI-H2818 GDSC1 12.8185 16.4846 10.3716 9.6973
NCI-H64 GDSC1 12.9242 17.3189 10.0399 11.7685
NCI-H2369 GDSC1 12.9428 14.9787 11.1747 3.4613
NCI-H1793 GDSC1 12.9677 19.0591 9.2156 16.9989
COR-L321 GDSC1 12.9998 21.0591 8.2495 22.0233
NCI-H2227 GDSC1 13 14.5958 11.3798 1.9583
NCI-H23 GDSC1 13.0786 21.8451 7.9201 23.2594
NCI-H1573 GDSC1 13.1371 18.92 9.41 15.2975
NCI-H2172 GDSC1 13.1831 19.0468 9.3815 15.3356
NCI-H1838 GDSC1 13.1916 23.5027 7.1843 25.8104
RERF-LC-MS GDSC1 13.24 14.8824 11.3826 1.561
NCI-H2869 GDSC1 13.2642 15.0821 11.3104 1.9557
LB647-SCLC GDSC1 13.2917 15.1641 11.2896 2.0392
NCI-H748 GDSC1 13.3229 20.7817 8.6313 19.1597
EMC-BAC-2 GDSC1 13.3429 15.6242 11.1167 3.054
NCI-H2373 GDSC1 13.3454 19.1293 9.4586 14.3821
HOP-92 GDSC1 13.3691 20.3215 8.892 17.6337
NCI-H1650 GDSC1 13.3948 23.3468 7.418 24.3598
NCI-H2595 GDSC1 13.3994 19.1185 9.5023 13.9545
NCI-H2135 GDSC1 13.4002 14.9469 11.4334 1.0781
HARA [Human squamous cell lung carcinoma] GDSC1 13.4022 19.7954 9.1739 15.9369
NCI-H209 GDSC1 13.4418 15.3426 11.291 1.8041
NCI-H1781 GDSC1 13.4435 14.8082 11.5072 0.6877
NCI-H2591 GDSC1 13.4478 17.4687 10.3297 8.2912
NCI-H2291 GDSC1 13.4794 15.5154 11.2372 2.0655
NCI-H2461 GDSC1 13.5425 16.4744 10.8504 4.4503
NCI-H441 GDSC1 13.6094 24.2969 7.1107 24.8911
NCI-H2804 GDSC1 13.6262 16.2067 11.0169 3.1922
SBC-1 GDSC1 13.7292 22.5735 8.0501 20.7888
NCI-H1568 GDSC1 13.8274 17.6922 10.4651 6.4693
IST-SL2 GDSC1 13.8329 15.8061 11.2888 1.3225
NCI-H2444 GDSC1 13.866 25.5675 6.6764 25.6795
EMC-BAC-1 GDSC1 13.8868 16.0833 11.2023 1.7063
NCI-H2803 GDSC1 14.013 15.4192 11.5093 0.3199
NCI-H2722 GDSC1 14.1389 15.6093 11.4891 0.319
HCC78 GDSC1 14.1978 15.6035 11.5126 0.2405
HCC827 GDSC1 14.2239 29.8575 4.8251 29.7681
IST-SL1 GDSC1 14.3915 16.1374 11.3965 0.4583
NCI-H2731 GDSC1 14.4075 16.1825 11.3864 0.4799
NCI-H2342 GDSC1 15.1246 31.9671 4.4601 28.6057
⏷ Show the Full List of 171 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC1 8.1817 12.3617 7.7215 47.8899
Cancer Drug Sensitivity Data Curated from 24 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KYSE-180 GDSC1 6.7785 11.5829 6.4046 60.6103
TE-15 GDSC1 7.7834 14.4347 6.5513 51.3191
KYSE-450 GDSC1 8.0432 10.2021 8.0076 49.0645
KYSE-510 GDSC1 8.6125 12.052 8.2824 43.1075
KYSE-520 GDSC1 9.262 12.0785 8.9835 35.377
KYSE-410 GDSC1 9.9967 13.5462 9.2465 29.3648
OE19 GDSC1 11.0251 22.2789 6.0058 36.1369
TE-6 GDSC1 11.1939 12.4931 10.9378 11.421
OE21 GDSC1 11.4188 15.7441 9.6034 20.1596
TE-11 GDSC1 11.4296 12.1092 11.336 7.3317
TE-8 GDSC1 11.4446 12.544 11.1774 8.4047
TE-9 GDSC1 11.4464 11.899 11.4157 6.6916
TE-10 GDSC1 11.5018 12.3575 11.3169 7.0917
KYSE-70 GDSC1 11.6161 12.2476 11.4824 5.3024
TE-1 GDSC1 11.6243 18.4924 8.4137 26.0416
TE-4 GDSC1 12.0447 16.704 9.6621 17.3042
TE-5 GDSC1 12.3394 21.3312 7.5907 26.9585
EC-GI-10 GDSC1 12.4409 24.7887 5.9458 31.7396
T.T GDSC1 13.0334 15.1216 11.1638 3.3443
KYSE-270 GDSC1 13.12 19.9314 8.8992 18.3424
COLO 680N GDSC1 14.0043 15.3608 11.5266 0.2789
OE33 GDSC1 14.3473 16.0722 11.403 0.4614
KYSE-140 GDSC1 14.5336 16.4482 11.3392 0.5573
KYSE-150 GDSC1 15.447 28.3568 6.459 22.5941
⏷ Show the Full List of 24 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A2780 GDSC1 5.2282 12.9517 4.3218 66.9786
ES-2 GDSC1 8.2557 11.287 8.0799 46.7567
Caov-3 GDSC1 8.5228 11.0188 8.4181 43.4524
OAW28 GDSC1 9.3626 12.5998 8.9295 34.9785
OV-90 GDSC1 9.7546 13.1583 9.1474 31.3482
TOV-112D GDSC1 10.0368 15.9219 8.2162 34.0862
RMG-I GDSC1 10.0451 12.4458 9.7214 26.129
OVCAR-8 GDSC1 10.7649 15.4084 9.164 25.8304
OVISE GDSC1 11.0587 14.1411 10.0533 18.6137
TYK-nu GDSC1 11.0749 13.6532 10.2996 16.7335
FU-OV-1 GDSC1 11.0842 12.0983 10.9645 11.8165
SK-OV-3 GDSC1 11.0922 15.135 9.605 21.5712
IGROV-1 GDSC1 11.1327 12.3238 10.9387 11.7337
OVTOKO GDSC1 11.2265 14.627 9.978 18.4002
EFO-27 GDSC1 11.3343 12.3762 11.1332 9.2828
TOV-21G GDSC1 11.3811 11.9849 11.3224 7.6953
OVCAR-5 GDSC1 11.4028 12.1251 11.3015 7.7189
Kuramochi GDSC1 11.5634 12.2804 11.4135 6.0736
EFO-21 GDSC1 11.8192 15.8468 9.9018 16.503
OVCAR-3 GDSC1 11.9307 23.4989 6.1699 32.7348
OAW42 GDSC1 12.2268 21.2213 7.5537 27.4772
DOV13 GDSC1 12.6193 14.4172 11.2325 3.7999
OVCAR-4 GDSC1 12.6584 29.1399 3.9489 35.1692
OVK18 GDSC1 13.329 14.8682 11.4319 1.169
JHOS-2 GDSC1 13.3598 15.0276 11.3814 1.4032
OV56 GDSC1 13.444 14.4578 11.6367 0.2296
OVKATE GDSC1 13.5343 19.7064 9.312 14.7405
OC 314 GDSC1 14.345 25.9406 6.8484 23.8785
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
KP-4 GDSC1 7.1319 11.6347 6.7771 57.7841
SUIT-2 GDSC1 7.5351 9.8641 7.5031 55.136
PSN1 GDSC1 7.5927 10.6375 7.4794 54.1654
MZ-PC-1 GDSC1 7.9935 12.5613 7.4546 49.7416
HuP-T4 GDSC1 8.5163 10.0598 8.506 43.1693
Panc 03.27 GDSC1 8.5335 10.9759 8.4365 43.2963
Panc 02.03 GDSC1 8.6525 12.4197 8.2165 42.964
BxPC-3 GDSC1 9.6993 11.4138 9.6182 28.845
HuP-T3 GDSC1 9.7114 12.27 9.4162 30.0368
Panc 10.05 GDSC1 9.8031 11.7784 9.654 27.9871
QGP-1 GDSC1 9.8132 18.3521 6.8394 39.2221
KP-3 GDSC1 10.2652 13.1389 9.6963 25.0647
Panc 08.13 GDSC1 10.3393 13.2252 9.7387 24.3829
HPAC GDSC1 10.3833 12.2881 10.1411 21.3939
YAPC GDSC1 10.4984 12.049 10.3409 19.3804
PL4 GDSC1 10.758 13.6259 9.9961 20.4549
PaTu 8902 GDSC1 10.7658 16.8381 8.4693 29.422
SU.86.86 GDSC1 11.1081 12.6019 10.803 12.8395
PaTu 8988t GDSC1 11.1392 16.8546 8.8024 26.1129
HPAF-II GDSC1 11.3221 12.3597 11.127 9.3907
KP-2 GDSC1 11.3482 11.8363 11.3223 7.8863
Capan-1 GDSC1 11.532 19.7016 7.7307 29.2971
DAN-G GDSC1 11.6846 25.3269 5.0495 35.9027
AsPC-1 GDSC1 12.1209 14.0238 11.0631 6.5762
Capan-2 GDSC1 12.5549 14.396 11.1997 4.212
MIA PaCa-2 GDSC1 13.0501 21.1447 8.2457 21.8855
Hs 766T GDSC1 13.146 18.8332 9.4592 14.9641
CFPAC-1 GDSC1 13.5494 15.08 11.448 0.8533
SW1990 GDSC1 13.6267 19.5658 9.4452 13.6747
Panc 04.03 GDSC1 17.2143 31.4973 6.1514 20.0172
⏷ Show the Full List of 30 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IST-Mes1 GDSC1 11.7654 12.7276 11.4073 5.1881
MSTO-211H GDSC1 12.3348 14.3149 11.0828 5.7353
NCI-H2452 GDSC1 12.9346 15.745 10.8098 6.1333
NCI-H28 GDSC1 13.3337 15.4175 11.2025 2.5145
NCI-H2052 GDSC1 13.4324 17.1286 10.4804 7.2711
MPP 89 GDSC1 13.5241 15.3153 11.3426 1.405
⏷ Show the Full List of 6 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 5 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LNCaP clone FGC GDSC1 10.8927 19.9373 7.0539 34.0367
PC-3 GDSC1 12.4562 20.562 8.0692 24.6008
VCaP GDSC1 12.7571 14.3139 11.3673 2.5074
DU145 GDSC1 12.9244 14.9058 11.1971 3.3437
22Rv1 GDSC1 13.7072 15.6797 11.2812 1.507
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC1 11.4375 21.163 6.9198 32.3652
Cancer Drug Sensitivity Data Curated from 56 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 792 GDSC1 0.5014 582.7053 -283.013 50.7042
MZ-MEL-7 GDSC1 6.6489 9.5955 6.599 64.6495
G-361 GDSC1 6.6755 9.659 6.6214 64.3071
LB2518-MEL GDSC1 6.8872 10.7341 6.7046 60.874
SK-MEL-30 GDSC1 7.5797 10.1999 7.5209 54.4956
WM115 GDSC1 7.6578 9.9952 7.6214 53.6722
CP66-MEL GDSC1 7.7413 11.9659 7.3554 52.1823
IST-MEL1 GDSC1 7.7472 11.5579 7.4665 52.2364
IPC-298 GDSC1 7.8523 11.0843 7.6829 51.2429
G-mel GDSC1 8.1945 11.0205 8.0642 47.3868
Mel JuSo GDSC1 8.2127 10.8207 8.1162 47.1205
A-431 GDSC1 8.2296 11.4622 8.014 47.1122
SH-4 GDSC1 8.3464 9.7272 8.3424 45.2601
IGR-1 GDSC1 8.4587 12.9208 7.8407 45.3573
RPMI-7951 GDSC1 8.5074 12.5566 8.0151 44.6315
SK-MEL-24 GDSC1 8.5584 11.3138 8.4028 43.1971
A101D GDSC1 8.6891 11.1675 8.5719 41.4972
WM1552C GDSC1 8.8085 10.9941 8.7285 39.8808
MeWo GDSC1 9.0221 21.0396 4.7909 45.3884
M14 GDSC1 9.0237 11.7725 8.8057 37.9257
IGR-37 GDSC1 9.2221 11.0027 9.1691 34.6173
COLO 679 GDSC1 9.3234 12.5469 8.9048 35.3626
WM793 GDSC1 9.3604 11.1438 9.2974 32.9558
WM35 GDSC1 9.4051 14.3733 8.2804 37.4621
HMV-II GDSC1 9.8634 11.4046 9.7966 26.7055
A2058 GDSC1 9.8695 12.9289 9.3581 29.4422
CP50-MEL-B GDSC1 9.8895 11.7577 9.7531 26.8305
LOX-IMVI GDSC1 9.8897 14.0584 8.9172 31.7769
HT-144 GDSC1 9.967 11.0773 9.9481 25.1039
WM278 GDSC1 9.9913 11.7925 9.8557 25.5573
SK-MEL-5 GDSC1 10.0448 23.398 4.5792 41.8153
A-375 GDSC1 10.087 15.8067 8.3196 33.4109
UACC-257 GDSC1 10.2463 12.5426 9.9053 23.766
Hs 938.T GDSC1 10.4581 15.2803 8.9301 28.6378
SK-MEL-3 GDSC1 10.5616 12.2942 10.3326 19.0849
RVH-421 GDSC1 10.6684 14.0277 9.7228 22.79
UACC-62 GDSC1 11.123 13.7164 10.3172 16.3802
SK-MEL-1 GDSC1 11.1697 15.2231 9.6339 21.0323
451Lu GDSC1 11.1864 18.7396 7.9093 29.9695
MZ-MEL-2 GDSC1 11.2998 21.1318 6.8166 33.1617
GAK GDSC1 11.3009 11.9856 11.2347 8.7464
MMAc-SF GDSC1 11.3237 15.9928 9.395 21.9066
VMRC-MELG GDSC1 11.3283 12.621 11.0242 10.1125
CHL-1 GDSC1 11.3325 12.3781 11.1305 9.3114
LB373-MEL-D GDSC1 11.373 11.8109 11.3537 7.5334
SK-MEL-28 GDSC1 11.4264 11.7504 11.419 6.7895
COLO 800 GDSC1 12.9587 27.3202 5.0995 32.2592
COLO 783 GDSC1 13.0405 14.7407 11.3385 2.1535
Mel Ho GDSC1 13.1454 14.6487 11.4331 1.4032
COLO 829 GDSC1 13.2247 15.4921 11.1084 3.3356
A-388 GDSC1 13.2364 17.8436 10.0067 11.098
Hs 940.T GDSC1 13.4436 15.7627 11.1115 2.9058
WT2-iPS GDSC1 13.8446 31.7393 3.5979 32.9989
SK-MEL-2 GDSC1 13.8581 23.71 7.5864 22.4059
DJM-1 GDSC1 14.0847 15.733 11.4239 0.5404
EquiPSC Line K2 GDSC1 10.9954 14.5826 9.7811 20.8257
⏷ Show the Full List of 56 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC1 4.8534 7.2796 4.8499 83.8212
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
G-401 GDSC1 6.0543 12.4522 5.3753 63.9165
SK-LMS-1 GDSC1 7.542 10.711 7.4136 54.6675
G-402 GDSC1 8.7105 15.0992 7.2494 44.4662
SK-UT-1 GDSC1 11.4798 12.0672 11.4046 6.5775
KYM-1 GDSC1 12.2841 21.9933 7.2148 28.5065
Rh30 GDSC1 12.4776 23.7477 6.4958 30.1563
EW-8 GDSC1 12.641 15.0696 10.9342 5.9862
SW982 GDSC1 12.7421 14.5259 11.2604 3.2998
VA-ES-BJ GDSC1 12.8624 15.8284 10.721 6.9827
Rh41 GDSC1 12.9855 16.8579 10.3087 9.6744
SW872 GDSC1 13.3944 15.5995 11.156 2.7061
A-204 GDSC1 13.5269 18.9642 9.6667 12.5557
MES-SA GDSC1 13.6357 14.7758 11.5958 0.2546
SW684 GDSC1 13.6385 20.3128 9.0908 15.7454
MFH-ino GDSC1 13.7591 20.7857 8.9463 16.2235
HT-1080 GDSC1 14.1006 19.8493 9.6296 11.303
Hs 633.T GDSC1 14.1108 20.6402 9.2597 13.507
GCT GDSC1 14.398 20.761 9.3924 12.0187
RD GDSC1 14.4859 21.1198 9.2801 12.4643
RKN GDSC1 14.924 28.3292 6.0994 24.8833
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 26 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HGC-27 GDSC1 7.4865 11.5826 7.1765 54.7259
SNU-5 GDSC1 9.6399 41.9077 -4.985 47.1706
Fu97 GDSC1 10.5117 17.6786 7.8225 33.2121
IM95 GDSC1 10.5172 21.1093 6.1371 37.7205
SNU-1 GDSC1 11.1407 15.7431 9.352 22.9719
SNU-16 GDSC1 11.3906 21.7825 6.5702 33.5077
RF-48 GDSC1 11.4699 16.0164 9.5137 20.5336
NUGC-3 GDSC1 11.5517 12.1693 11.4456 5.9016
TGBC11TKB GDSC1 11.5936 20.2772 7.496 29.9278
NCI-N87 GDSC1 11.7095 13.1902 11.1288 7.592
ECC10 GDSC1 11.7558 16.0583 9.742 17.8593
MKN1 GDSC1 11.8876 24.7274 5.5197 34.3683
MKN45 GDSC1 11.8919 21.9874 6.8933 30.8569
GCIY GDSC1 11.9145 19.3542 8.2287 25.7945
MKN28 GDSC1 12.2573 23.4121 6.4837 30.87
OCUM-1 GDSC1 12.4199 21.2255 7.7087 26.23
23132/87 GDSC1 12.5309 17.1683 9.8191 14.5387
RERF-GC-1B GDSC1 12.9761 15.6682 10.8737 5.5581
MKN7 GDSC1 13.1424 16.1178 10.7694 5.9092
NUGC-4 GDSC1 13.1657 15.3756 11.1266 3.3292
TMK-1 GDSC1 13.3729 20.7668 8.6758 18.7806
HSC-39 GDSC1 13.4637 15.0636 11.416 1.0947
Hs 746.T GDSC1 13.7707 15.3663 11.4328 0.7261
SCH GDSC1 14.1815 22.9347 8.2002 18.8774
AGS GDSC1 14.757 23.6806 8.2397 17.2415
SNG-M GDSC1 13.3925 14.7537 11.5062 0.7378
⏷ Show the Full List of 26 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
8305C GDSC1 11.6042 18.3355 8.4748 25.8297
TT GDSC1 12.2242 13.8579 11.2255 4.9667
BHT-101 GDSC1 12.3621 20.4125 8.068 24.9243
B-CPAP GDSC1 12.381 13.6309 11.4486 2.7972
ML-1 [Human leukemia] GDSC1 12.6489 14.2444 11.333 2.9911
HTC-C3 GDSC1 12.8256 14.6091 11.2734 3.02
CGTH-W-1 GDSC1 13.0842 17.1426 10.2398 9.8908
TT2609-C02 GDSC1 13.215 15.1679 11.2469 2.4365
CAL-62 GDSC1 13.232 19.7162 9.0885 16.9349
WRO GDSC1 13.2486 17.629 10.1189 10.2881
8505C GDSC1 13.2966 19.6404 9.1731 16.2506
K5 GDSC1 13.5114 19.0094 9.6341 12.8069
KMH-2 GDSC1 13.5905 25.4483 6.5261 26.8864
FTC-133 GDSC1 13.8483 19.4713 9.6422 11.8581
IHH-4 GDSC1 13.9054 22.1617 8.38 18.7605
ASH-3 GDSC1 14.0677 21.6502 8.7437 16.4834
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BICR 22 GDSC1 0.977 20.7447 -3.1929 68.2405
SCC-25 GDSC1 5.7235 11.1009 5.3686 68.1766
BB30-HNC GDSC1 8.0666 13.3231 7.2755 49.1386
BHY GDSC1 8.5092 13.2338 7.7845 45.0489
SCC-9 GDSC1 8.6375 17.3887 6.1505 46.1126
KOSC-2 GDSC1 9.6049 12.5364 9.2136 31.8941
SCC-15 GDSC1 10.4958 17.5639 7.8638 33.1379
PCI-04B GDSC1 10.5477 14.6188 9.3292 25.9177
LB771-HNC GDSC1 10.7979 19.9349 6.9705 34.6496
OSC-19 GDSC1 11.2401 13.1244 10.7088 12.8959
HO-1-N-1 GDSC1 11.3106 12.3705 11.1105 9.5691
HSC-3 GDSC1 11.3209 18.3543 8.2194 28.1365
PCI-06A GDSC1 11.3264 19.0484 7.8785 29.5264
JHU-011 GDSC1 11.3615 13.1932 10.7967 11.6687
SCC-4 GDSC1 11.3683 19.5992 7.6404 30.2619
HO-1-u-1 GDSC1 11.3736 12.5994 11.0803 9.4736
OSC-20 GDSC1 11.3862 12.409 11.1746 8.7164
BICR 78 GDSC1 11.4021 19.9239 7.5078 30.6058
PCI-38 GDSC1 11.4228 12.3877 11.2217 8.1864
Ca9-22 GDSC1 11.4377 18.2398 8.3785 26.9472
HSC-2 GDSC1 11.448 20.9952 7.0126 32.05
CAL-33 GDSC1 11.5872 12.567 11.3115 6.7178
NCI-H3118 GDSC1 11.6139 18.0707 8.6153 25.1013
CAL-27 GDSC1 11.7202 19.3637 8.0602 27.2583
Detroit 562 GDSC1 11.9982 24.1541 5.8987 33.1843
JHU-022 GDSC1 12.1268 13.6194 11.269 4.9387
SAS GDSC1 12.1364 24.168 6.0062 32.5016
FaDu GDSC1 12.4042 22.2276 7.1955 28.1824
PCI-30 GDSC1 12.6629 16.638 10.1821 11.5515
BB49-HNC GDSC1 13.0249 17.9865 9.786 13.2086
BICR 10 GDSC1 13.1587 16.2067 10.738 6.0964
PCI-15A GDSC1 13.3986 15.1235 11.3608 1.4665
SAT [Human HNSCC] GDSC1 13.8451 19.8635 9.4522 13.0459
DOK GDSC1 14.0079 16.5774 11.0574 2.3475
HSC-4 GDSC1 14.0762 27.1249 6.0651 27.0036
PE/CA-PJ15 GDSC1 14.249 25.0434 7.2184 22.7993
SKN-3 GDSC1 14.559 23.5099 8.1859 17.9784
KON GDSC1 15.096 29.8984 5.4555 26.2944
BICR 31 GDSC1 15.4444 23.9149 8.5817 14.0141
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
UM-UC-3 GDSC1 9.4795 11.5028 9.3634 31.7978
SW780 GDSC1 9.9886 14.4923 8.8273 31.6656
HT-1376 GDSC1 10.5473 12.1253 10.3714 18.8964
J82 GDSC1 11.4475 13.2419 10.8571 10.8201
KU-19-19 GDSC1 11.9353 34.577 0.6347 40.6006
RT-4 GDSC1 12.765 21.576 7.8094 24.7022
BFTC-905 GDSC1 12.9851 18.7568 9.3778 15.9603
CAL-29 GDSC1 13.0659 15.1023 11.1918 3.0842
639V GDSC1 13.0827 20.8666 8.4085 21.0069
5637 GDSC1 13.3413 15.701 11.0817 3.2888
T24 GDSC1 13.7708 15.4865 11.3868 0.9222
HT-1197 GDSC1 13.8168 16.2399 11.103 2.3575
SW1710 GDSC1 14.1574 21.1947 9.0254 14.7236
TCCSUP GDSC1 14.515 20.4251 9.6249 10.3549
647V GDSC1 14.7885 21.8365 9.1378 12.5622
RT-112 GDSC1 15.1721 26.0933 7.3627 20.0046
⏷ Show the Full List of 16 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SKG-IIIa GDSC1 -0.0969 32.7175 -9.6177 63.1053
C-33 A GDSC1 4.6885 21.9325 0.1137 60.0824
KGN GDSC1 5.4983 9.8127 5.3577 72.48
SW954 GDSC1 6.1197 9.3005 6.0696 69.707
SiHa GDSC1 6.4812 38.9597 -6.3361 52.4936
OMC-1 [Human cervical carcinoma] GDSC1 8.0802 13.5615 7.2032 49.0488
DoTc2 4510 GDSC1 8.5646 13.9245 7.582 44.9612
PA-1 GDSC1 8.5794 10.7236 8.5205 42.5956
HeLa GDSC1 9.2868 14.9565 7.9052 39.403
HT-3 GDSC1 9.3482 16.4103 7.3094 40.5501
SW962 GDSC1 9.6953 15.8567 7.9102 37.0123
JEG-3 GDSC1 10.0179 15.128 8.5677 32.7245
Ca Ski GDSC1 10.3588 17.2527 7.8873 33.6953
OVMIU GDSC1 10.457 12.8525 10.0141 21.8719
SiSo GDSC1 10.581 15.8614 8.7706 28.8502
MS751 GDSC1 11.0073 17.5082 8.3602 28.8353
NT2-D1 GDSC1 11.3502 12.3969 11.1417 9.1396
ME-180 GDSC1 11.3552 12.3441 11.1682 8.9212
NCC-IT GDSC1 11.3615 21.8225 6.5252 33.7283
HEC-1 GDSC1 11.7105 12.8496 11.2965 6.2815
C-4-I GDSC1 12.0745 13.4571 11.3087 4.8015
JAR GDSC1 12.2557 20.6702 7.8527 26.202
PEO1 GDSC1 12.4296 16.8822 9.8826 14.4383
BPH-1 GDSC1 12.4452 19.5788 8.5511 22.369
SW756 GDSC1 12.5338 14.8716 10.9547 6.1327
SKN GDSC1 12.7326 15.2309 10.9196 5.8459
HEY GDSC1 13.0586 15.2685 11.1119 3.6532
NEC8 GDSC1 13.1314 14.5103 11.4836 1.1377
JHOS-3 GDSC1 13.3496 15.7557 11.062 3.4043
UWB1.289 GDSC1 13.3631 17.5101 10.2539 9.0383
CAL-39 GDSC1 13.3832 16.3171 10.8272 4.9445
OV17R GDSC1 13.5533 17.4997 10.3835 7.6568
LB831-BLC GDSC1 13.6123 17.8045 10.2781 8.2438
OVCA433 GDSC1 13.6647 15.5793 11.3019 1.4493
DSH1 GDSC1 13.8264 15.3855 11.4486 0.6221
ACC-OV7 GDSC1 13.9585 16.0496 11.2492 1.382
OVCA420 GDSC1 13.9802 15.4194 11.4968 0.3695
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug

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